2Y82B

Structure and property based design of factor xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine p4 motifs
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
52
structure length
52
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Aminoindane and Phenylpyrrolidine P4 Motifs.
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords ACTIVATED FACTOR XA HEAVY CHAIN
total genus 13
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2011-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00008 EGF EGF-like domain
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2y82B00
1LMJA 1F7EA 2VWNL 5CKQA 5EGMB 1NFXB 3DEMA 1IGZA 2XC4L 1N7DA 4YT6L 1IQKL 1LPGA 4C16A 4ZHAB 3IITB 4RRZA 1LPZA 2CJIB 4BTIA 1NT0A 2W2QE 3KK6A 4M10A 4Y6DB 2W2PE 4ISHL 3TZIA 1EMNA 1LPKA 1XKAL 1JL9A 3HO4A 1ZAQA 1TLEA 1G2MB 2WPLE 2Y7ZB 2XBVL 6COXA 2W3KB 1KLJL 1P9JA 3N8XA 4XLWA 4COXA 2XBYL 5KIRA 4Z6AL 3GISX 4Y79B 2BOHA 4OTYA 3Q7DA 1PTHA 1PXXA 3N8WA 1ATBA 2GD4A 1Q4GA 1F0SB 2KB9A 1SZBA 2FLBL 1KIGL 4OTJA 2J38B 1U67A 3LIWB 3F6UL 1CX2A 2AYLA 5JBAE 3P5BL 2WPKE 2J94B 1C5MF 1TOZA 2VWOL 3TGFA 4MMZB 3LC3B 4ZXYL 1F7MA 2YGOA 1IQIL 3F1SB 4Y7BB 2J4IB 3LC5B 3MQEA 3BPSE 1EPGA 5JW1A 1ATDA 3CENL 2FLRL 2Y82B 1NFUB 4NGAL 4ZAEB 2VVVL 2Y7XB 2FD6A 1G1RA 1JBUL 2EI8B 4BTTA 1EAIC 2UWPB 3GCWE 3KQDL 4BXSA 1CVWL 1G1TA 2VVUL 1QFKL 3V64C 2FLGA 1OB1C 2K2TA 2Y38A 4BTUA 2F9BL 2WPIE 2P3TA 5CKNA 1ADXA 2OYUP 5CISA 3N8ZA 2VJ3A 1G2LB 1FFMA 1FAKL 1U8CB 2WFTA 3SW2A 4X8UL 4JZDL 3EGFA 1EPJA 4D0EA 4RS0A 1HAEA 2BQWA 5IKQA 3HO5A 1GK5A 2BZ6L 2G00L 3KL6B 3BT2A 4FM5A 3NJPC 3CS7L 1DVAL 1FF7A 3KQBL 1IJQA 2P3FL 2MGPA 4Y71B 3H5CB 1ATAA 2D1JB 2VWLL 1Z6CA 3ENSA 3R05A 5COXA 1MQ6L 4D0FA 2VWMK 2WFXB 4LMFA 3M36L 1IOXA 1NPEB 3TK5B 1BF9A 1KLIL 4BXWA 3N8YA 1KLOA 4RUTA 1CCFA 4BDWA 4JYUL 3TK6B 1APQA 5JBCE 1YUFA 4JZFL 1EQGA 5L2ZL 2UWOB 2PHBB 2PUQL 5E8DA 5IKTA 1HCGB 1FSBA 1P0SL 2Y80B 5CKMA 2ADXA 2RHPA 3K9XA 3ELAL 3U7UG 5L30L 1W7XL 2VVCK 1EPHA 2W86A 5K0HB 3N8VA 1O5DL 1G1QA 2WYJB 1YO8A 1XKBA 3KQEL 2XBWL 1HREA 5KN5C 2I9BA 1TPGA 3GCXE 4BDXA 1MQ5L 4RRYA 2WPJE 1X7AL 4ZH8B 1YGCL 3HS5A 1CVUA 2MHPA 4YT7L 3NTGA 2JKHL 2M74A 1IQLL 4PH9A 1EZQB 2W3IB 1IVOC 1URKA 5JVYA 2FZZL 1HX2A 4TGFA 4AQTA 5JVZA 3PGHA 2WPHE 1J9CL 1NFWB 1CQEA 4YZUB 1K37A 2BOKL 1L3YA 2BQ7A 4MMXB 4G1MB 1XFEA 3POYA 2EI6B 1B9WA 4M11A 2P3FN 1WHEA 1DIYA 1EMOA 3ZYIB 1EQHA 2VH0B 3N8WB 3KRKA 5IKRA 3RR3A 2Y81B 4Y76B 1IOEL 1PFXL 1G1SA 1M1XB 2WPME 2P95L 2WYGB 3U73A 5JB9E 2J2UB 1YUKB 2VH6B 2P94L 1UZQA 3V65B 1IGXA 4XL1A 3TH3L 3HS7A 1UZJA 3OLTA 1HT5A 2BMGA 2UWLB 4CSYA 3ASIA 2XC0L 1ATEA 2Y5GL 2J34B 3KCGL 1IQJL 1WU1B 1NZIA 1PRHA 2H9EL 4NA9L 2BQ6A 4CUFA 4Y7AB 3QCWA 3IJEB 2P28B 1EGFA 2WG4B 2I9AA 1COUA 4A7IA 1APOA 3LAQA 1HT8A 3FCSB 2W26B 3BT1A 3SOVA 1HZ8A 2J95B 1L5GB 2BO2A 2P26A 5IKVA 1CEJA 1RFNB 1IQML 1IQGL 1PGEA 2W2NE 1JV2B 2YGPA 4X8VL 1UZKA 2Y5FL 2MGRA 1DDXA 2PR3B 2KV4A 2P93L 2P3UA 5FDQA 3QH0A 1EBVA 2XC5L 3ZYJB 5I46L 2BOXA 4MMYB 4JZEL 1CCVA 3LN0A 3SOQA 3CFWA 4X8SL 1DQBA 1Z6EL 4X8TL 5F19A 4RRWA 1V3XB 1F0RB 1YUGA 1NFYB 4XBMA 4Z0LA 1WHFA 3M37L 3CA7A 2BOUA 1FE2A 2P16L 4O02B 4CUDA 3HS6A 4O1ZA 5JB8E 4Z0KB 1N1IA 3FFGL 1HAFA 1IQEL 1LQDA 2WG3C 1KSNB 2RA0L 1FJSL 3ZYGA 4D90A 3MDLA 3HPTA 1W8BL 1FAXL 2W2ME 3NT1A 4LORA 3SOBB 3NTBA 1A3PA 3N8YB 2DDUA 2Y5HL 5JBBE 3TBDA 2XBXL 1NQLB 1IQNL 1IQHL 1MOXC 3KQCL 1HRFA 3OLUA 2Q1JB 1K36A 4ISIL 1XDTR 3QMOA 2K2SB 3LN1A 2W2OE 2EI7B 1EPIA 1DX5I 2OYEP 3LTFB 4JYVL 2B7DL 5F1AA 4ZXXL 1UZPA 4E1GA 2RNLA 4CUEA 1HJ7A 1I0UA 2TGFA 2NPRA 1AUTL 1IQFL 3FBYA 5L2YL 3C9AC 4NG9L 3Q3KB 2KL7A 3HO3A 3LTGD 4RRXA 1IP0A
chains in the Genus database with same CATH superfamily
1LMJA 1F7EA 2VWNL 5CKQA 5EGMB 1NFXB 3DEMA 1IGZA 2XC4L 1N7DA 4YT6L 1IQKL 1LPGA 4C16A 4ZHAB 3IITB 4RRZA 1LPZA 2CJIB 4BTIA 1NT0A 2W2QE 3KK6A 4M10A 4Y6DB 2W2PE 4ISHL 3TZIA 1EMNA 1LPKA 1XKAL 1JL9A 3HO4A 1ZAQA 1TLEA 1G2MB 2WPLE 2Y7ZB 2XBVL 6COXA 2W3KB 1KLJL 1P9JA 3N8XA 4XLWA 4COXA 2XBYL 5KIRA 4Z6AL 3GISX 4Y79B 2BOHA 4OTYA 3Q7DA 1PTHA 1PXXA 3N8WA 1ATBA 2GD4A 1Q4GA 1F0SB 2KB9A 2HOXA 1SZBA 2FLBL 1KIGL 4OTJA 2J38B 1U67A 3LIWB 3F6UL 1CX2A 2AYLA 2KNIA 5JBAE 3P5BL 2WPKE 2J94B 1C5MF 1TOZA 2VWOL 3TGFA 4MMZB 3LC3B 4ZXYL 1F7MA 2YGOA 1IQIL 3S6XA 3F1SB 4Y7BB 2J4IB 3LC5B 3MQEA 3BPSE 1EPGA 5JW1A 1ATDA 3CENL 2HORA 2FLRL 2Y82B 1QIUA 1NFUB 4NGAL 4ZAEB 4A94C 2VVVL 2Y7XB 2FD6A 1G1RA 1JBUL 2EI8B 4BTTA 1EAIC 2UWPB 3GCWE 3KQDL 4BXSA 1CVWL 1G1TA 2VVUL 1QFKL 3V64C 2FLGA 1OB1C 2K2TA 2Y38A 4BTUA 2F9BL 2WPIE 2P3TA 5CKNA 1ADXA 2OYUP 5CISA 3N8ZA 2VJ3A 1G2LB 1FFMA 1FAKL 1U8CB 2WFTA 3SW2A 4X8UL 4JZDL 3EGFA 1EPJA 4D0EA 4RS0A 1HAEA 2BT7A 2BQWA 5IKQA 3HO5A 1GK5A 2BZ6L 2G00L 3KL6B 3BT2A 4FM5A 3NJPC 3CS7L 1DVAL 1FF7A 3KQBL 1IJQA 2P3FL 2MGPA 4Y71B 3H5CB 1ATAA 2D1JB 2VWLL 1Z6CA 3ENSA 3R05A 5COXA 1MQ6L 4D0FA 2VWMK 2WFXB 4LMFA 3M36L 1IOXA 1NPEB 3TK5B 1BF9A 1KLIL 4BXWA 3N8YA 1KLOA 4RUTA 1CCFA 2H9EC 4BDWA 4JYUL 3TK6B 1APQA 5JBCE 1YUFA 4JZFL 1EQGA 5L2ZL 2UWOB 2PHBB 2PUQL 5E8DA 5IKTA 1HCGB 1FSBA 1P0SL 2Y80B 5CKMA 1KKEA 2ADXA 2RHPA 3K9XA 3ELAL 3U7UG 5L30L 1W7XL 2VVCK 1EPHA 2W86A 5K0HB 3N8VA 1O5DL 1G1QA 2WYJB 1YO8A 1XKBA 3KQEL 2XBWL 1HREA 5KN5C 2I9BA 2BT8A 1TPGA 3GCXE 4BDXA 1MQ5L 4RRYA 2WPJE 1X7AL 4ZH8B 1YGCL 3HS5A 1CVUA 2MHPA 4YT7L 2JJLA 3NTGA 2JKHL 2M74A 1IQLL 4PH9A 2WZPP 1EZQB 2W3IB 1IVOC 1URKA 5JVYA 2FZZL 1HX2A 4TGFA 4AQTA 5JVZA 3PGHA 2WPHE 1J9CL 1NFWB 1CQEA 4YZUB 1K37A 2BOKL 1L3YA 2BQ7A 4MMXB 4G1MB 1XFEA 3POYA 2EI6B 1B9WA 4M11A 2P3FN 1WHEA 1DIYA 1EMOA 3ZYIB 1EQHA 2VH0B 3N8WB 3KRKA 5IKRA 3RR3A 2Y81B 4Y76B 1IOEL 1PFXL 1G1SA 1M1XB 2WPME 2P95L 2WYGB 3U73A 5JB9E 2J2UB 1YUKB 2VH6B 2P94L 1UZQA 3V65B 1IGXA 4XL1A 3TH3L 3HS7A 1UZJA 1LMMA 3OLTA 1HT5A 2BMGA 2UWLB 4CSYA 3ASIA 2XC0L 1ATEA 2Y5GL 2J34B 3KCGL 1IQJL 1LK9A 4GU3A 1WU1B 1NZIA 1PRHA 2H9EL 4NA9L 2BQ6A 4CUFA 4Y7AB 1V1IA 3QCWA 3IJEB 2P28B 1EGFA 2WG4B 2I9AA 1COUA 4A7IA 1APOA 3LAQA 1HT8A 3FCSB 2W26B 3BT1A 3SOVA 1V1HA 2BSFA 1HZ8A 2J95B 1L5GB 2BO2A 2P26A 5IKVA 1CEJA 1RFNB 1IQML 1IQGL 1PGEA 2W2NE 1JV2B 2YGPA 4X8VL 1UZKA 2Y5FL 2MGRA 1DDXA 2PR3B 2KV4A 2P93L 2P3UA 5FDQA 3QH0A 1EBVA 2XC5L 3ZYJB 5I46L 2BOXA 4MMYB 4JZEL 1CCVA 3LN0A 3SOQA 3CFWA 4X8SL 1DQBA 1Z6EL 4X8TL 5F19A 4RRWA 1V3XB 1F0RB 1YUGA 1NFYB 2YGQA 4XBMA 4Z0LA 1WHFA 3M37L 3CA7A 2BOUA 1FE2A 2P16L 4O02B 4CUDA 3HS6A 4O1ZA 5JB8E 4Z0KB 1N1IA 3FFGL 1HAFA 1IQEL 1LQDA 2WG3C 1KSNB 2RA0L 1FJSL 3ZYGA 4D90A 3MDLA 3HPTA 1W8BL 1FAXL 2W2ME 3NT1A 4LORA 3SOBB 3NTBA 1A3PA 3N8YB 2DDUA 2Y5HL 5JBBE 3TBDA 2XBXL 1NQLB 1IQNL 1IQHL 1MOXC 3KQCL 1HRFA 3OLUA 2Q1JB 1K36A 4ISIL 1XDTR 3QMOA 2K2SB 3LN1A 2W2OE 2EI7B 1EPIA 1DX5I 4GU4A 2OYEP 3LTFB 4JYVL 2B7DL 5F1AA 4ZXXL 2VRSA 1UZPA 4E1GA 2RNLA 4CUEA 1HJ7A 1I0UA 2TGFA 2NPRA 1AUTL 1IQFL 3FBYA 5L2YL 3C9AC 4NG9L 3Q3KB 2KL7A 3HO3A 3LTGD 4RRXA 1IP0A
chains in the Genus database with same CATH topology
1LMJA 1F7EA 2VWNL 5CKQA 5EGMB 1NFXB 3DEMA 1IGZA 2XC4L 1N7DA 4YT6L 1IQKL 1LPGA 4C16A 4ZHAB 3IITB 4RRZA 1LPZA 2CJIB 4BTIA 1NT0A 2W2QE 3KK6A 4M10A 4Y6DB 2W2PE 4ISHL 3TZIA 1EMNA 1LPKA 1XKAL 1JL9A 3HO4A 1ZAQA 1TLEA 1G2MB 2WPLE 2Y7ZB 2XBVL 6COXA 2W3KB 1KLJL 1P9JA 3N8XA 4XLWA 4COXA 2XBYL 5KIRA 4Z6AL 3GISX 4Y79B 2BOHA 4OTYA 3Q7DA 1PTHA 1PXXA 3N8WA 1ATBA 2GD4A 1Q4GA 1F0SB 2KB9A 1SZBA 2FLBL 1KIGL 4OTJA 2J38B 1U67A 3LIWB 3F6UL 1CX2A 2AYLA 2KNIA 5JBAE 3P5BL 2WPKE 2J94B 1C5MF 1TOZA 2VWOL 3TGFA 4MMZB 3LC3B 4ZXYL 1F7MA 2YGOA 1IQIL 3S6XA 3F1SB 4Y7BB 2J4IB 3LC5B 3MQEA 3BPSE 1EPGA 5JW1A 1ATDA 3CENL 2FLRL 2Y82B 1NFUB 4NGAL 4ZAEB 4A94C 2VVVL 2Y7XB 2FD6A 1G1RA 1JBUL 2EI8B 4BTTA 1EAIC 2UWPB 3GCWE 3KQDL 4BXSA 1CVWL 1G1TA 2VVUL 1QFKL 3V64C 2FLGA 1OB1C 2K2TA 2Y38A 4BTUA 2F9BL 2WPIE 2P3TA 5CKNA 1ADXA 2OYUP 5CISA 3N8ZA 2VJ3A 1G2LB 1FFMA 1FAKL 1U8CB 2WFTA 3SW2A 4X8UL 4JZDL 3EGFA 1EPJA 4D0EA 4RS0A 1HAEA 2BQWA 5IKQA 3HO5A 1GK5A 2BZ6L 2G00L 3KL6B 3BT2A 4FM5A 3NJPC 3CS7L 1DVAL 1FF7A 3KQBL 1IJQA 2P3FL 2MGPA 4Y71B 3H5CB 1ATAA 2D1JB 2VWLL 1Z6CA 3ENSA 3R05A 5COXA 1MQ6L 4D0FA 2VWMK 2WFXB 4LMFA 3M36L 1IOXA 1NPEB 3TK5B 1BF9A 1KLIL 4BXWA 3N8YA 1KLOA 4RUTA 1CCFA 2H9EC 4BDWA 4JYUL 3TK6B 1APQA 5JBCE 1YUFA 4JZFL 1EQGA 5L2ZL 2UWOB 2PHBB 2PUQL 5E8DA 5IKTA 1HCGB 1FSBA 1P0SL 2Y80B 5CKMA 2ADXA 2RHPA 3K9XA 3ELAL 3U7UG 5L30L 1W7XL 2VVCK 1EPHA 2W86A 5K0HB 3N8VA 1O5DL 1G1QA 2WYJB 1YO8A 1XKBA 3KQEL 2XBWL 1HREA 5KN5C 2I9BA 1TPGA 3GCXE 4BDXA 1MQ5L 4RRYA 2WPJE 1X7AL 4ZH8B 1YGCL 3HS5A 1CVUA 2MHPA 4YT7L 3NTGA 2JKHL 2M74A 1IQLL 4PH9A 2WZPP 1EZQB 2W3IB 1IVOC 1URKA 5JVYA 2FZZL 1HX2A 4TGFA 4AQTA 5JVZA 3PGHA 2WPHE 1J9CL 1NFWB 1CQEA 4YZUB 1K37A 2BOKL 1L3YA 2BQ7A 4MMXB 4G1MB 1XFEA 3POYA 2EI6B 1B9WA 4M11A 2P3FN 1WHEA 1DIYA 1EMOA 3ZYIB 1EQHA 2VH0B 3N8WB 3KRKA 5IKRA 3RR3A 2Y81B 4Y76B 1IOEL 1PFXL 1G1SA 1M1XB 2WPME 2P95L 2WYGB 3U73A 5JB9E 2J2UB 1YUKB 2VH6B 2P94L 1UZQA 3V65B 1IGXA 4XL1A 3TH3L 3HS7A 1UZJA 1LMMA 3OLTA 1HT5A 2BMGA 2UWLB 4CSYA 3ASIA 2XC0L 1ATEA 2Y5GL 2J34B 3KCGL 1IQJL 1WU1B 1NZIA 1PRHA 2H9EL 4NA9L 2BQ6A 4CUFA 4Y7AB 3QCWA 3IJEB 2P28B 1EGFA 2WG4B 2I9AA 1COUA 4A7IA 1APOA 3LAQA 1HT8A 3FCSB 2W26B 3BT1A 3SOVA 1HZ8A 2J95B 1L5GB 2BO2A 2P26A 5IKVA 1CEJA 1RFNB 1IQML 1IQGL 1PGEA 2W2NE 1JV2B 2YGPA 4X8VL 1UZKA 2Y5FL 2MGRA 1DDXA 2PR3B 2KV4A 2P93L 2P3UA 5FDQA 3QH0A 1EBVA 2XC5L 3ZYJB 5I46L 2BOXA 4MMYB 4JZEL 1CCVA 3LN0A 3SOQA 3CFWA 4X8SL 1DQBA 1Z6EL 4X8TL 5F19A 4RRWA 1V3XB 1F0RB 1YUGA 1NFYB 2YGQA 4XBMA 4Z0LA 1WHFA 3M37L 3CA7A 2BOUA 1FE2A 2P16L 4O02B 4CUDA 3HS6A 4O1ZA 5JB8E 4Z0KB 1N1IA 3FFGL 1HAFA 1IQEL 1LQDA 2WG3C 1KSNB 2RA0L 1FJSL 3ZYGA 4D90A 3MDLA 3HPTA 1W8BL 1FAXL 2W2ME 3NT1A 4LORA 3SOBB 3NTBA 1A3PA 3N8YB 2DDUA 2Y5HL 5JBBE 3TBDA 2XBXL 1NQLB 1IQNL 1IQHL 1MOXC 3KQCL 1HRFA 3OLUA 2Q1JB 1K36A 4ISIL 1XDTR 3QMOA 2K2SB 3LN1A 2W2OE 2EI7B 1EPIA 1DX5I 2OYEP 3LTFB 4JYVL 2B7DL 5F1AA 4ZXXL 1UZPA 4E1GA 2RNLA 4CUEA 1HJ7A 1I0UA 2TGFA 2NPRA 1AUTL 1IQFL 3FBYA 5L2YL 3C9AC 4NG9L 3Q3KB 2KL7A 3HO3A 3LTGD 4RRXA 1IP0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LMJ A;  1F7E A;  2VWN L;  5CKQ A;  5EGM B;  1NFX B;  3DEM A;  1IGZ A;  2XC4 L;  1N7D A;  4YT6 L;  1IQK L;  1LPG A;  4C16 A;  4ZHA B;  3IIT B;  4RRZ A;  1LPZ A;  2CJI B;  4BTI A;  1NT0 A;  2W2Q E;  3KK6 A;  4M10 A;  4Y6D B;  2W2P E;  4ISH L;  3TZI A;  1EMN A;  1LPK A;  1XKA L;  1JL9 A;  3HO4 A;  1ZAQ A;  1TLE A;  1G2M B;  2WPL E;  2Y7Z B;  2XBV L;  6COX A;  2W3K B;  1KLJ L;  1P9J A;  3N8X A;  4XLW A;  4COX A;  2XBY L;  5KIR A;  4Z6A L;  3GIS X;  4Y79 B;  2BOH A;  4OTY A;  3Q7D A;  1PTH A;  1PXX A;  3N8W A;  1ATB A;  2GD4 A;  1Q4G A;  1F0S B;  2KB9 A;  1SZB A;  2FLB L;  1KIG L;  4OTJ A;  2J38 B;  1U67 A;  3LIW B;  3F6U L;  1CX2 A;  2AYL A;  5JBA E;  3P5B L;  2WPK E;  2J94 B;  1C5M F;  1TOZ A;  2VWO L;  3TGF A;  4MMZ B;  3LC3 B;  4ZXY L;  1F7M A;  2YGO A;  1IQI L;  3F1S B;  4Y7B B;  2J4I B;  3LC5 B;  3MQE A;  3BPS E;  1EPG A;  5JW1 A;  1ATD A;  3CEN L;  2FLR L;  2Y82 B;  1NFU B;  4NGA L;  4ZAE B;  2VVV L;  2Y7X B;  2FD6 A;  1G1R A;  1JBU L;  2EI8 B;  4BTT A;  1EAI C;  2UWP B;  3GCW E;  3KQD L;  4BXS A;  1CVW L;  1G1T A;  2VVU L;  1QFK L;  3V64 C;  2FLG A;  1OB1 C;  2K2T A;  2Y38 A;  4BTU A;  2F9B L;  2WPI E;  2P3T A;  5CKN A;  1ADX A;  2OYU P;  5CIS A;  3N8Z A;  2VJ3 A;  1G2L B;  1FFM A;  1FAK L;  1U8C B;  2WFT A;  3SW2 A;  4X8U L;  4JZD L;  3EGF A;  1EPJ A;  4D0E A;  4RS0 A;  1HAE A;  2BQW A;  5IKQ A;  3HO5 A;  1GK5 A;  2BZ6 L;  2G00 L;  3KL6 B;  3BT2 A;  4FM5 A;  3NJP C;  3CS7 L;  1DVA L;  1FF7 A;  3KQB L;  1IJQ A;  2P3F L;  2MGP A;  4Y71 B;  3H5C B;  1ATA A;  2D1J B;  2VWL L;  1Z6C A;  3ENS A;  3R05 A;  5COX A;  1MQ6 L;  4D0F A;  2VWM K;  2WFX B;  4LMF A;  3M36 L;  1IOX A;  1NPE B;  3TK5 B;  1BF9 A;  1KLI L;  4BXW A;  3N8Y A;  1KLO A;  4RUT A;  1CCF A;  4BDW A;  4JYU L;  3TK6 B;  1APQ A;  5JBC E;  1YUF A;  4JZF L;  1EQG A;  5L2Z L;  2UWO B;  2PHB B;  2PUQ L;  5E8D A;  5IKT A;  1HCG B;  1FSB A;  1P0S L;  2Y80 B;  5CKM A;  2ADX A;  2RHP A;  3K9X A;  3ELA L;  3U7U G;  5L30 L;  1W7X L;  2VVC K;  1EPH A;  2W86 A;  5K0H B;  3N8V A;  1O5D L;  1G1Q A;  2WYJ B;  1YO8 A;  1XKB A;  3KQE L;  2XBW L;  1HRE A;  5KN5 C;  2I9B A;  1TPG A;  3GCX E;  4BDX A;  1MQ5 L;  4RRY A;  2WPJ E;  1X7A L;  4ZH8 B;  1YGC L;  3HS5 A;  1CVU A;  2MHP A;  4YT7 L;  3NTG A;  2JKH L;  2M74 A;  1IQL L;  4PH9 A;  1EZQ B;  2W3I B;  1IVO C;  1URK A;  5JVY A;  2FZZ L;  1HX2 A;  4TGF A;  4AQT A;  5JVZ A;  3PGH A;  2WPH E;  1J9C L;  1NFW B;  1CQE A;  4YZU B;  1K37 A;  2BOK L;  1L3Y A;  2BQ7 A;  4MMX B;  4G1M B;  1XFE A;  3POY A;  2EI6 B;  1B9W A;  4M11 A;  2P3F N;  1WHE A;  1DIY A;  1EMO A;  3ZYI B;  1EQH A;  2VH0 B;  3N8W B;  3KRK A;  5IKR A;  3RR3 A;  2Y81 B;  4Y76 B;  1IOE L;  1PFX L;  1G1S A;  1M1X B;  2WPM E;  2P95 L;  2WYG B;  3U73 A;  5JB9 E;  2J2U B;  1YUK B;  2VH6 B;  2P94 L;  1UZQ A;  3V65 B;  1IGX A;  4XL1 A;  3TH3 L;  3HS7 A;  1UZJ A;  3OLT A;  1HT5 A;  2BMG A;  2UWL B;  4CSY A;  3ASI A;  2XC0 L;  1ATE A;  2Y5G L;  2J34 B;  3KCG L;  1IQJ L;  1WU1 B;  1NZI A;  1PRH A;  2H9E L;  4NA9 L;  2BQ6 A;  4CUF A;  4Y7A B;  3QCW A;  3IJE B;  2P28 B;  1EGF A;  2WG4 B;  2I9A A;  1COU A;  4A7I A;  1APO A;  3LAQ A;  1HT8 A;  3FCS B;  2W26 B;  3BT1 A;  3SOV A;  1HZ8 A;  2J95 B;  1L5G B;  2BO2 A;  2P26 A;  5IKV A;  1CEJ A;  1RFN B;  1IQM L;  1IQG L;  1PGE A;  2W2N E;  1JV2 B;  2YGP A;  4X8V L;  1UZK A;  2Y5F L;  2MGR A;  1DDX A;  2PR3 B;  2KV4 A;  2P93 L;  2P3U A;  5FDQ A;  3QH0 A;  1EBV A;  2XC5 L;  3ZYJ B;  5I46 L;  2BOX A;  4MMY B;  4JZE L;  1CCV A;  3LN0 A;  3SOQ A;  3CFW A;  4X8S L;  1DQB A;  1Z6E L;  4X8T L;  5F19 A;  4RRW A;  1V3X B;  1F0R B;  1YUG A;  1NFY B;  4XBM A;  4Z0L A;  1WHF A;  3M37 L;  3CA7 A;  2BOU A;  1FE2 A;  2P16 L;  4O02 B;  4CUD A;  3HS6 A;  4O1Z A;  5JB8 E;  4Z0K B;  1N1I A;  3FFG L;  1HAF A;  1IQE L;  1LQD A;  2WG3 C;  1KSN B;  2RA0 L;  1FJS L;  3ZYG A;  4D90 A;  3MDL A;  3HPT A;  1W8B L;  1FAX L;  2W2M E;  3NT1 A;  4LOR A;  3SOB B;  3NTB A;  1A3P A;  3N8Y B;  2DDU A;  2Y5H L;  5JBB E;  3TBD A;  2XBX L;  1NQL B;  1IQN L;  1IQH L;  1MOX C;  3KQC L;  1HRF A;  3OLU A;  2Q1J B;  1K36 A;  4ISI L;  1XDT R;  3QMO A;  2K2S B;  3LN1 A;  2W2O E;  2EI7 B;  1EPI A;  1DX5 I;  2OYE P;  3LTF B;  4JYV L;  2B7D L;  5F1A A;  4ZXX L;  1UZP A;  4E1G A;  2RNL A;  4CUE A;  1HJ7 A;  1I0U A;  2TGF A;  2NPR A;  1AUT L;  1IQF L;  3FBY A;  5L2Y L;  3C9A C;  4NG9 L;  3Q3K B;  2KL7 A;  3HO3 A;  3LTG D;  4RRX A;  1IP0 A; 
#chains in the Genus database with same CATH topology
 1LMJ A;  1F7E A;  2VWN L;  5CKQ A;  5EGM B;  1NFX B;  3DEM A;  1IGZ A;  2XC4 L;  1N7D A;  4YT6 L;  1IQK L;  1LPG A;  4C16 A;  4ZHA B;  3IIT B;  4RRZ A;  1LPZ A;  2CJI B;  4BTI A;  1NT0 A;  2W2Q E;  3KK6 A;  4M10 A;  4Y6D B;  2W2P E;  4ISH L;  3TZI A;  1EMN A;  1LPK A;  1XKA L;  1JL9 A;  3HO4 A;  1ZAQ A;  1TLE A;  1G2M B;  2WPL E;  2Y7Z B;  2XBV L;  6COX A;  2W3K B;  1KLJ L;  1P9J A;  3N8X A;  4XLW A;  4COX A;  2XBY L;  5KIR A;  4Z6A L;  3GIS X;  4Y79 B;  2BOH A;  4OTY A;  3Q7D A;  1PTH A;  1PXX A;  3N8W A;  1ATB A;  2GD4 A;  1Q4G A;  1F0S B;  2KB9 A;  2HOX A;  1SZB A;  2FLB L;  1KIG L;  4OTJ A;  2J38 B;  1U67 A;  3LIW B;  3F6U L;  1CX2 A;  2AYL A;  2KNI A;  5JBA E;  3P5B L;  2WPK E;  2J94 B;  1C5M F;  1TOZ A;  2VWO L;  3TGF A;  4MMZ B;  3LC3 B;  4ZXY L;  1F7M A;  2YGO A;  1IQI L;  3S6X A;  3F1S B;  4Y7B B;  2J4I B;  3LC5 B;  3MQE A;  3BPS E;  1EPG A;  5JW1 A;  1ATD A;  3CEN L;  2HOR A;  2FLR L;  2Y82 B;  1QIU A;  1NFU B;  4NGA L;  4ZAE B;  4A94 C;  2VVV L;  2Y7X B;  2FD6 A;  1G1R A;  1JBU L;  2EI8 B;  4BTT A;  1EAI C;  2UWP B;  3GCW E;  3KQD L;  4BXS A;  1CVW L;  1G1T A;  2VVU L;  1QFK L;  3V64 C;  2FLG A;  1OB1 C;  2K2T A;  2Y38 A;  4BTU A;  2F9B L;  2WPI E;  2P3T A;  5CKN A;  1ADX A;  2OYU P;  5CIS A;  3N8Z A;  2VJ3 A;  1G2L B;  1FFM A;  1FAK L;  1U8C B;  2WFT A;  3SW2 A;  4X8U L;  4JZD L;  3EGF A;  1EPJ A;  4D0E A;  4RS0 A;  1HAE A;  2BT7 A;  2BQW A;  5IKQ A;  3HO5 A;  1GK5 A;  2BZ6 L;  2G00 L;  3KL6 B;  3BT2 A;  4FM5 A;  3NJP C;  3CS7 L;  1DVA L;  1FF7 A;  3KQB L;  1IJQ A;  2P3F L;  2MGP A;  4Y71 B;  3H5C B;  1ATA A;  2D1J B;  2VWL L;  1Z6C A;  3ENS A;  3R05 A;  5COX A;  1MQ6 L;  4D0F A;  2VWM K;  2WFX B;  4LMF A;  3M36 L;  1IOX A;  1NPE B;  3TK5 B;  1BF9 A;  1KLI L;  4BXW A;  3N8Y A;  1KLO A;  4RUT A;  1CCF A;  2H9E C;  4BDW A;  4JYU L;  3TK6 B;  1APQ A;  5JBC E;  1YUF A;  4JZF L;  1EQG A;  5L2Z L;  2UWO B;  2PHB B;  2PUQ L;  5E8D A;  5IKT A;  1HCG B;  1FSB A;  1P0S L;  2Y80 B;  5CKM A;  1KKE A;  2ADX A;  2RHP A;  3K9X A;  3ELA L;  3U7U G;  5L30 L;  1W7X L;  2VVC K;  1EPH A;  2W86 A;  5K0H B;  3N8V A;  1O5D L;  1G1Q A;  2WYJ B;  1YO8 A;  1XKB A;  3KQE L;  2XBW L;  1HRE A;  5KN5 C;  2I9B A;  2BT8 A;  1TPG A;  3GCX E;  4BDX A;  1MQ5 L;  4RRY A;  2WPJ E;  1X7A L;  4ZH8 B;  1YGC L;  3HS5 A;  1CVU A;  2MHP A;  4YT7 L;  2JJL A;  3NTG A;  2JKH L;  2M74 A;  1IQL L;  4PH9 A;  2WZP P;  1EZQ B;  2W3I B;  1IVO C;  1URK A;  5JVY A;  2FZZ L;  1HX2 A;  4TGF A;  4AQT A;  5JVZ A;  3PGH A;  2WPH E;  1J9C L;  1NFW B;  1CQE A;  4YZU B;  1K37 A;  2BOK L;  1L3Y A;  2BQ7 A;  4MMX B;  4G1M B;  1XFE A;  3POY A;  2EI6 B;  1B9W A;  4M11 A;  2P3F N;  1WHE A;  1DIY A;  1EMO A;  3ZYI B;  1EQH A;  2VH0 B;  3N8W B;  3KRK A;  5IKR A;  3RR3 A;  2Y81 B;  4Y76 B;  1IOE L;  1PFX L;  1G1S A;  1M1X B;  2WPM E;  2P95 L;  2WYG B;  3U73 A;  5JB9 E;  2J2U B;  1YUK B;  2VH6 B;  2P94 L;  1UZQ A;  3V65 B;  1IGX A;  4XL1 A;  3TH3 L;  3HS7 A;  1UZJ A;  1LMM A;  3OLT A;  1HT5 A;  2BMG A;  2UWL B;  4CSY A;  3ASI A;  2XC0 L;  1ATE A;  2Y5G L;  2J34 B;  3KCG L;  1IQJ L;  1LK9 A;  4GU3 A;  1WU1 B;  1NZI A;  1PRH A;  2H9E L;  4NA9 L;  2BQ6 A;  4CUF A;  4Y7A B;  1V1I A;  3QCW A;  3IJE B;  2P28 B;  1EGF A;  2WG4 B;  2I9A A;  1COU A;  4A7I A;  1APO A;  3LAQ A;  1HT8 A;  3FCS B;  2W26 B;  3BT1 A;  3SOV A;  1V1H A;  2BSF A;  1HZ8 A;  2J95 B;  1L5G B;  2BO2 A;  2P26 A;  5IKV A;  1CEJ A;  1RFN B;  1IQM L;  1IQG L;  1PGE A;  2W2N E;  1JV2 B;  2YGP A;  4X8V L;  1UZK A;  2Y5F L;  2MGR A;  1DDX A;  2PR3 B;  2KV4 A;  2P93 L;  2P3U A;  5FDQ A;  3QH0 A;  1EBV A;  2XC5 L;  3ZYJ B;  5I46 L;  2BOX A;  4MMY B;  4JZE L;  1CCV A;  3LN0 A;  3SOQ A;  3CFW A;  4X8S L;  1DQB A;  1Z6E L;  4X8T L;  5F19 A;  4RRW A;  1V3X B;  1F0R B;  1YUG A;  1NFY B;  2YGQ A;  4XBM A;  4Z0L A;  1WHF A;  3M37 L;  3CA7 A;  2BOU A;  1FE2 A;  2P16 L;  4O02 B;  4CUD A;  3HS6 A;  4O1Z A;  5JB8 E;  4Z0K B;  1N1I A;  3FFG L;  1HAF A;  1IQE L;  1LQD A;  2WG3 C;  1KSN B;  2RA0 L;  1FJS L;  3ZYG A;  4D90 A;  3MDL A;  3HPT A;  1W8B L;  1FAX L;  2W2M E;  3NT1 A;  4LOR A;  3SOB B;  3NTB A;  1A3P A;  3N8Y B;  2DDU A;  2Y5H L;  5JBB E;  3TBD A;  2XBX L;  1NQL B;  1IQN L;  1IQH L;  1MOX C;  3KQC L;  1HRF A;  3OLU A;  2Q1J B;  1K36 A;  4ISI L;  1XDT R;  3QMO A;  2K2S B;  3LN1 A;  2W2O E;  2EI7 B;  1EPI A;  1DX5 I;  4GU4 A;  2OYE P;  3LTF B;  4JYV L;  2B7D L;  5F1A A;  4ZXX L;  2VRS A;  1UZP A;  4E1G A;  2RNL A;  4CUE A;  1HJ7 A;  1I0U A;  2TGF A;  2NPR A;  1AUT L;  1IQF L;  3FBY A;  5L2Y L;  3C9A C;  4NG9 L;  3Q3K B;  2KL7 A;  3HO3 A;  3LTG D;  4RRX A;  1IP0 A; 
#chains in the Genus database with same CATH homology
 1LMJ A;  1F7E A;  2VWN L;  5CKQ A;  5EGM B;  1NFX B;  3DEM A;  1IGZ A;  2XC4 L;  1N7D A;  4YT6 L;  1IQK L;  1LPG A;  4C16 A;  4ZHA B;  3IIT B;  4RRZ A;  1LPZ A;  2CJI B;  4BTI A;  1NT0 A;  2W2Q E;  3KK6 A;  4M10 A;  4Y6D B;  2W2P E;  4ISH L;  3TZI A;  1EMN A;  1LPK A;  1XKA L;  1JL9 A;  3HO4 A;  1ZAQ A;  1TLE A;  1G2M B;  2WPL E;  2Y7Z B;  2XBV L;  6COX A;  2W3K B;  1KLJ L;  1P9J A;  3N8X A;  4XLW A;  4COX A;  2XBY L;  5KIR A;  4Z6A L;  3GIS X;  4Y79 B;  2BOH A;  4OTY A;  3Q7D A;  1PTH A;  1PXX A;  3N8W A;  1ATB A;  2GD4 A;  1Q4G A;  1F0S B;  2KB9 A;  1SZB A;  2FLB L;  1KIG L;  4OTJ A;  2J38 B;  1U67 A;  3LIW B;  3F6U L;  1CX2 A;  2AYL A;  2KNI A;  5JBA E;  3P5B L;  2WPK E;  2J94 B;  1C5M F;  1TOZ A;  2VWO L;  3TGF A;  4MMZ B;  3LC3 B;  4ZXY L;  1F7M A;  2YGO A;  1IQI L;  3S6X A;  3F1S B;  4Y7B B;  2J4I B;  3LC5 B;  3MQE A;  3BPS E;  1EPG A;  5JW1 A;  1ATD A;  3CEN L;  2FLR L;  2Y82 B;  1NFU B;  4NGA L;  4ZAE B;  4A94 C;  2VVV L;  2Y7X B;  2FD6 A;  1G1R A;  1JBU L;  2EI8 B;  4BTT A;  1EAI C;  2UWP B;  3GCW E;  3KQD L;  4BXS A;  1CVW L;  1G1T A;  2VVU L;  1QFK L;  3V64 C;  2FLG A;  1OB1 C;  2K2T A;  2Y38 A;  4BTU A;  2F9B L;  2WPI E;  2P3T A;  5CKN A;  1ADX A;  2OYU P;  5CIS A;  3N8Z A;  2VJ3 A;  1G2L B;  1FFM A;  1FAK L;  1U8C B;  2WFT A;  3SW2 A;  4X8U L;  4JZD L;  3EGF A;  1EPJ A;  4D0E A;  4RS0 A;  1HAE A;  2BQW A;  5IKQ A;  3HO5 A;  1GK5 A;  2BZ6 L;  2G00 L;  3KL6 B;  3BT2 A;  4FM5 A;  3NJP C;  3CS7 L;  1DVA L;  1FF7 A;  3KQB L;  1IJQ A;  2P3F L;  2MGP A;  4Y71 B;  3H5C B;  1ATA A;  2D1J B;  2VWL L;  1Z6C A;  3ENS A;  3R05 A;  5COX A;  1MQ6 L;  4D0F A;  2VWM K;  2WFX B;  4LMF A;  3M36 L;  1IOX A;  1NPE B;  3TK5 B;  1BF9 A;  1KLI L;  4BXW A;  3N8Y A;  1KLO A;  4RUT A;  1CCF A;  2H9E C;  4BDW A;  4JYU L;  3TK6 B;  1APQ A;  5JBC E;  1YUF A;  4JZF L;  1EQG A;  5L2Z L;  2UWO B;  2PHB B;  2PUQ L;  5E8D A;  5IKT A;  1HCG B;  1FSB A;  1P0S L;  2Y80 B;  5CKM A;  2ADX A;  2RHP A;  3K9X A;  3ELA L;  3U7U G;  5L30 L;  1W7X L;  2VVC K;  1EPH A;  2W86 A;  5K0H B;  3N8V A;  1O5D L;  1G1Q A;  2WYJ B;  1YO8 A;  1XKB A;  3KQE L;  2XBW L;  1HRE A;  5KN5 C;  2I9B A;  1TPG A;  3GCX E;  4BDX A;  1MQ5 L;  4RRY A;  2WPJ E;  1X7A L;  4ZH8 B;  1YGC L;  3HS5 A;  1CVU A;  2MHP A;  4YT7 L;  3NTG A;  2JKH L;  2M74 A;  1IQL L;  4PH9 A;  2WZP P;  1EZQ B;  2W3I B;  1IVO C;  1URK A;  5JVY A;  2FZZ L;  1HX2 A;  4TGF A;  4AQT A;  5JVZ A;  3PGH A;  2WPH E;  1J9C L;  1NFW B;  1CQE A;  4YZU B;  1K37 A;  2BOK L;  1L3Y A;  2BQ7 A;  4MMX B;  4G1M B;  1XFE A;  3POY A;  2EI6 B;  1B9W A;  4M11 A;  2P3F N;  1WHE A;  1DIY A;  1EMO A;  3ZYI B;  1EQH A;  2VH0 B;  3N8W B;  3KRK A;  5IKR A;  3RR3 A;  2Y81 B;  4Y76 B;  1IOE L;  1PFX L;  1G1S A;  1M1X B;  2WPM E;  2P95 L;  2WYG B;  3U73 A;  5JB9 E;  2J2U B;  1YUK B;  2VH6 B;  2P94 L;  1UZQ A;  3V65 B;  1IGX A;  4XL1 A;  3TH3 L;  3HS7 A;  1UZJ A;  1LMM A;  3OLT A;  1HT5 A;  2BMG A;  2UWL B;  4CSY A;  3ASI A;  2XC0 L;  1ATE A;  2Y5G L;  2J34 B;  3KCG L;  1IQJ L;  1WU1 B;  1NZI A;  1PRH A;  2H9E L;  4NA9 L;  2BQ6 A;  4CUF A;  4Y7A B;  3QCW A;  3IJE B;  2P28 B;  1EGF A;  2WG4 B;  2I9A A;  1COU A;  4A7I A;  1APO A;  3LAQ A;  1HT8 A;  3FCS B;  2W26 B;  3BT1 A;  3SOV A;  1HZ8 A;  2J95 B;  1L5G B;  2BO2 A;  2P26 A;  5IKV A;  1CEJ A;  1RFN B;  1IQM L;  1IQG L;  1PGE A;  2W2N E;  1JV2 B;  2YGP A;  4X8V L;  1UZK A;  2Y5F L;  2MGR A;  1DDX A;  2PR3 B;  2KV4 A;  2P93 L;  2P3U A;  5FDQ A;  3QH0 A;  1EBV A;  2XC5 L;  3ZYJ B;  5I46 L;  2BOX A;  4MMY B;  4JZE L;  1CCV A;  3LN0 A;  3SOQ A;  3CFW A;  4X8S L;  1DQB A;  1Z6E L;  4X8T L;  5F19 A;  4RRW A;  1V3X B;  1F0R B;  1YUG A;  1NFY B;  2YGQ A;  4XBM A;  4Z0L A;  1WHF A;  3M37 L;  3CA7 A;  2BOU A;  1FE2 A;  2P16 L;  4O02 B;  4CUD A;  3HS6 A;  4O1Z A;  5JB8 E;  4Z0K B;  1N1I A;  3FFG L;  1HAF A;  1IQE L;  1LQD A;  2WG3 C;  1KSN B;  2RA0 L;  1FJS L;  3ZYG A;  4D90 A;  3MDL A;  3HPT A;  1W8B L;  1FAX L;  2W2M E;  3NT1 A;  4LOR A;  3SOB B;  3NTB A;  1A3P A;  3N8Y B;  2DDU A;  2Y5H L;  5JBB E;  3TBD A;  2XBX L;  1NQL B;  1IQN L;  1IQH L;  1MOX C;  3KQC L;  1HRF A;  3OLU A;  2Q1J B;  1K36 A;  4ISI L;  1XDT R;  3QMO A;  2K2S B;  3LN1 A;  2W2O E;  2EI7 B;  1EPI A;  1DX5 I;  2OYE P;  3LTF B;  4JYV L;  2B7D L;  5F1A A;  4ZXX L;  1UZP A;  4E1G A;  2RNL A;  4CUE A;  1HJ7 A;  1I0U A;  2TGF A;  2NPR A;  1AUT L;  1IQF L;  3FBY A;  5L2Y L;  3C9A C;  4NG9 L;  3Q3K B;  2KL7 A;  3HO3 A;  3LTG D;  4RRX A;  1IP0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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