3CS7L

Factor xa in complex with the inhibitor 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin-7(4h)-one
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Achieving structural diversity using the perpendicular conformation of alpha-substituted phenylcyclopropanes to mimic the bioactive conformation of ortho-substituted biphenyl P4 moieties: discovery of novel, highly potent inhibitors of Factor Xa.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Coagulation factor X
total genus 13
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2008-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3cs7L00
1IQHL 3OLUA 1IGZA 3POYA 4JZEL 2FZZL 1FJSL 1EGFA 1IQIL 2P3FL 4O02B 1EZQB 2BQ6A 3BPSE 5L2YL 2XC5L 3M36L 2G00L 1WHFA 4Y6DB 3GCWE 3LAQA 1CCFA 3HO3A 1G2LB 5L2ZL 2XBYL 2FLBL 2P93L 4ZH8B 1GK5A 2VJ3A 2AYLA 2Q1JB 2VVCK 2BMGA 3TBDA 1IP0A 4YT7L 2NPRA 4CSYA 1HT5A 2UWLB 4ZAEB 5JBAE 3N8ZA 4BTUA 2Y5HL 5JVYA 3DEMA 2W2QE 3CS7L 4JYUL 3C9AC 5KN5C 1CCVA 1EBVA 3NT1A 3N8XA 3ASIA 2K2TA 4RUTA 2VWOL 1EPIA 3TGFA 4ISIL 1ZAQA 3Q7DA 4X8UL 2WPKE 4JZDL 1CEJA 2P3TA 1IJQA 2W3IB 2W2OE 4RRWA 2K2SB 4RS0A 4O1ZA 5CKQA 2TGFA 1P0SL 3V65B 2WPLE 1LMJA 4MMZB 4LMFA 2FD6A 3P5BL 3F1SB 1XFEA 2DDUA 4BTIA 1DIYA 4D0FA 2RA0L 1HT8A 1HAEA 1PRHA 1FSBA 4NGAL 5JBBE 2VWNL 1SZBA 1NFYB 1IVOC 5K0HB 2XBWL 1AUTL 1MQ6L 1WHEA 2M74A 5JVZA 1CVUA 1PFXL 2BOUA 3ZYJB 3RR3A 1P9JA 4CUDA 2OYUP 1NPEB 2W3KB 1KLOA 3Q3KB 4OTJA 3ENSA 4JZFL 2W26B 2P26A 1FF7A 1NFXB 2PHBB 2VH0B 1IQLL 2BQ7A 4XBMA 1LPGA 2UWOB 5E8DA 5IKRA 3FBYA 1IQFL 5IKTA 1DX5I 1IOEL 5IKVA 1EMNA 1G1RA 1N7DA 3KCGL 3NJPC 3HS7A 4BXSA 1F0SB 1EAIC 1G1TA 1EQHA 2J2UB 1G1QA 4OTYA 4ZXXL 2FLGA 3NTGA 1NFWB 6COXA 3R05A 3PGHA 1FFMA 1EMOA 4YT6L 1Z6CA 2VH6B 3N8VA 1FAXL 1APOA 2Y38A 1IQGL 1HCGB 1HZ8A 4D90A 4ZHAB 1KLJL 1EPGA 2J34B 1F0RB 1JV2B 2WFTA 3ELAL 2OYEP 1K36A 1JBUL 3FFGL 1RFNB 4LORA 4A7IA 5CKNA 1HRFA 1XKAL 2W2NE 3KQEL 3LTGD 2WFXB 1YGCL 1UZQA 1C5MF 1W8BL 3CENL 2BZ6L 4G1MB 3ZYIB 1DDXA 4M11A 5F19A 4X8VL 2D1JB 5JW1A 4XL1A 1I0UA 4BXWA 3KK6A 3KQBL 1EPJA 4Z0LA 3HS5A 3BT2A 2I9AA 1CVWL 2WG4B 1LPKA 1UZPA 2EI6B 4E1GA 1WU1B 2F9BL 2H9EL 3CFWA 1B9WA 1ATDA 1LPZA 2VWLL 1HAFA 1TOZA 4CUEA 3LN1A 3H5CB 1UZKA 1OB1C 5FDQA 1N1IA 2W2ME 1V3XB 1MQ5L 1TPGA 3GISX 1IQML 2UWPB 2MHPA 2B7DL 1NT0A 3N8YA 1A3PA 2VVVL 2P95L 3GCXE 2Y5GL 1MOXC 4Y71B 3MQEA 2BOHA 3TK6B 4RRYA 1Q4GA 4AQTA 1DVAL 1NFUB 1M1XB 1U8CB 3QCWA 2VWMK 1L3YA 2Y5FL 1W7XL 3QMOA 3IITB 3KQDL 2KB9A 2J38B 1KLIL 3FCSB 3M37L 1IQJL 2EI7B 2P16L 2WYJB 2Y7ZB 3ZYGA 1YUKB 3KRKA 2XBXL 3SOBB 3KQCL 2ADXA 4JYVL 4TGFA 4XLWA 1EQGA 3U7UG 1ATEA 1ATBA 1TLEA 2BQWA 3MDLA 1F7MA 4MMXB 2Y82B 2RHPA 4NG9L 1BF9A 3HPTA 5JB8E 4BDXA 4Y76B 1Z6EL 2BOXA 3LTFB 2W86A 2Y81B 1HJ7A 2WPME 1NQLB 2Y7XB 2MGPA 3IJEB 2BO2A 4FM5A 3U73A 4BDWA 2KV4A 1EPHA 3TZIA 3EGFA 1IOXA 2J95B 3TH3L 4ISHL 1PTHA 2PUQL 4X8SL 4Z6AL 1O5DL 1KSNB 3HS6A 3HO5A 3N8WA 2XC0L 1IQKL 4CUFA 4ZXYL 3LC5B 2GD4A 4COXA 2KL7A 3NTBA 2J94B 2J4IB 4NA9L 1X7AL 4Y7BB 2FLRL 2CJIB 2XC4L 2Y80B 1G1SA 1PXXA 4RRZA 2YGOA 2P3FN 3LC3B 4C16A 3HO4A 2YGPA 4YZUB 3N8WB 1XDTR 1APQA 2P94L 4PH9A 3LIWB 2BOKL 1K37A 2EI8B 2WYGB 4D0EA 1ADXA 2WG3C 3LN0A 1CX2A 1KIGL 1HX2A 5KIRA 5L30L 1QFKL 2P28B 5IKQA 1F7EA 3CA7A 1G2MB 3OLTA 5CKMA 2PR3B 1PGEA 1YUFA 1J9CL 2MGRA 2VVUL 1LQDA 1URKA 5CISA 1U67A 1COUA 2XBVL 1XKBA 1FE2A 3QH0A 4M10A 1NZIA 5F1AA 3F6UL 1IQEL 2WPJE 1ATAA 2P3UA 1JL9A 4Y7AB 1L5GB 5EGMB 5JB9E 3KL6B 4X8TL 3TK5B 3K9XA 5I46L 4MMYB 1UZJA 2I9BA 1YUGA 1IQNL 1CQEA 4Z0KB 4BTTA 3SW2A 1FAKL 3SOVA 3BT1A 5JBCE 2RNLA 2JKHL 3N8YB 2WPIE 2W2PE 3SOQA 1YO8A 1DQBA 5COXA 1HREA 2WPHE 1IGXA 4Y79B 4RRXA 3V64C
chains in the Genus database with same CATH superfamily
1IQHL 3OLUA 1IGZA 3POYA 4JZEL 2FZZL 1FJSL 1EGFA 1IQIL 2P3FL 4O02B 1EZQB 2BQ6A 3BPSE 2BSFA 5L2YL 2XC5L 3M36L 2HORA 2G00L 1WHFA 4Y6DB 3GCWE 3LAQA 1CCFA 3HO3A 1G2LB 5L2ZL 2XBYL 2FLBL 2P93L 4ZH8B 1GK5A 2VJ3A 2AYLA 2Q1JB 2VVCK 2BMGA 3TBDA 1IP0A 4YT7L 2NPRA 4CSYA 1HT5A 2H9EC 2UWLB 4ZAEB 5JBAE 3N8ZA 4BTUA 2Y5HL 5JVYA 3DEMA 2W2QE 3CS7L 4JYUL 3C9AC 5KN5C 1CCVA 1EBVA 3NT1A 3N8XA 1V1HA 2K2TA 3ASIA 4RUTA 2VWOL 1EPIA 3TGFA 4ISIL 1ZAQA 3Q7DA 4X8UL 2WPKE 4JZDL 1CEJA 2P3TA 1IJQA 2W3IB 2W2OE 4RRWA 2K2SB 4RS0A 4O1ZA 5CKQA 2TGFA 1P0SL 3V65B 2WPLE 1LMJA 4MMZB 4LMFA 2FD6A 3P5BL 3F1SB 1LMMA 1XFEA 2DDUA 4BTIA 1DIYA 2YGQA 4D0FA 2RA0L 1HT8A 1HAEA 1PRHA 1FSBA 4NGAL 5JBBE 2VWNL 1SZBA 1NFYB 1IVOC 5K0HB 2XBWL 1AUTL 1MQ6L 1WHEA 2M74A 5JVZA 1CVUA 1PFXL 2BOUA 3ZYJB 3RR3A 1P9JA 4CUDA 2OYUP 4GU3A 1NPEB 2W3KB 1KLOA 3Q3KB 4OTJA 3ENSA 4JZFL 1V1IA 2W26B 2P26A 1FF7A 1NFXB 2PHBB 2VH0B 1IQLL 2BQ7A 4XBMA 1LPGA 2UWOB 5E8DA 5IKRA 3FBYA 1IQFL 5IKTA 1DX5I 1IOEL 5IKVA 1EMNA 1G1RA 1N7DA 3KCGL 3NJPC 4A94C 3HS7A 4BXSA 1F0SB 1EAIC 1G1TA 1EQHA 2J2UB 1G1QA 4OTYA 4ZXXL 2FLGA 3NTGA 1NFWB 6COXA 3R05A 3PGHA 1FFMA 1EMOA 4YT6L 1Z6CA 2VH6B 3N8VA 1FAXL 1APOA 2KNIA 2Y38A 1IQGL 1HCGB 1HZ8A 4D90A 4ZHAB 1KLJL 1EPGA 2J34B 1F0RB 1JV2B 2WFTA 2VRSA 3ELAL 2OYEP 1K36A 1JBUL 3FFGL 1RFNB 4LORA 4A7IA 5CKNA 1HRFA 1XKAL 2HOXA 2W2NE 3KQEL 3LTGD 2WFXB 1YGCL 1UZQA 1C5MF 1W8BL 3CENL 2BZ6L 4G1MB 3ZYIB 1DDXA 4M11A 5F19A 4X8VL 2D1JB 5JW1A 4XL1A 1I0UA 4BXWA 3KK6A 3KQBL 1EPJA 4Z0LA 3HS5A 3BT2A 2I9AA 1CVWL 2WG4B 1LPKA 2BT8A 1UZPA 2EI6B 4E1GA 1WU1B 2F9BL 2H9EL 3CFWA 1B9WA 1ATDA 1LPZA 2VWLL 1HAFA 1TOZA 4CUEA 3LN1A 3H5CB 1UZKA 1OB1C 5FDQA 2WZPP 1N1IA 2W2ME 1V3XB 1MQ5L 1TPGA 3GISX 1IQML 2UWPB 2MHPA 2B7DL 1NT0A 3N8YA 1A3PA 2VVVL 2P95L 3GCXE 2Y5GL 1MOXC 4Y71B 3MQEA 2BOHA 3TK6B 4RRYA 1Q4GA 3S6XA 4AQTA 1DVAL 1NFUB 1M1XB 1U8CB 3QCWA 2VWMK 1L3YA 2Y5FL 1W7XL 3QMOA 4GU4A 3IITB 3KQDL 2KB9A 2J38B 1KLIL 3FCSB 3M37L 1IQJL 2EI7B 2P16L 2WYJB 2Y7ZB 3ZYGA 1YUKB 3KRKA 2XBXL 3SOBB 3KQCL 2ADXA 4JYVL 4TGFA 4XLWA 1EQGA 3U7UG 1ATEA 1ATBA 1TLEA 2BQWA 3MDLA 1F7MA 4MMXB 2Y82B 2RHPA 4NG9L 1BF9A 3HPTA 5JB8E 4BDXA 4Y76B 1Z6EL 2BOXA 3LTFB 2W86A 2Y81B 1HJ7A 2WPME 1NQLB 2Y7XB 2MGPA 3IJEB 2BO2A 4FM5A 3U73A 4BDWA 2KV4A 1EPHA 3TZIA 3EGFA 1IOXA 2J95B 3TH3L 4ISHL 1PTHA 2PUQL 4X8SL 4Z6AL 1O5DL 1KSNB 3HS6A 3HO5A 3N8WA 2XC0L 1IQKL 1QIUA 4CUFA 4ZXYL 3LC5B 1KKEA 2GD4A 2JJLA 4COXA 2KL7A 3NTBA 2J94B 2J4IB 4NA9L 1X7AL 4Y7BB 2FLRL 2CJIB 2XC4L 2Y80B 1G1SA 1PXXA 4RRZA 2YGOA 2P3FN 3LC3B 4C16A 3HO4A 2YGPA 4YZUB 3N8WB 1XDTR 1APQA 2P94L 4PH9A 3LIWB 2BOKL 1K37A 2EI8B 2WYGB 4D0EA 1ADXA 2WG3C 3LN0A 1CX2A 1KIGL 1HX2A 5KIRA 5L30L 1QFKL 2BT7A 2P28B 5IKQA 1F7EA 3CA7A 1G2MB 3OLTA 5CKMA 2PR3B 1PGEA 1YUFA 1J9CL 2MGRA 2VVUL 1LQDA 1URKA 5CISA 1U67A 1COUA 2XBVL 1XKBA 1FE2A 3QH0A 4M10A 1NZIA 5F1AA 3F6UL 1IQEL 2WPJE 1ATAA 2P3UA 1JL9A 4Y7AB 1L5GB 5EGMB 5JB9E 3KL6B 4X8TL 3TK5B 3K9XA 5I46L 4MMYB 1UZJA 2I9BA 1YUGA 1IQNL 1CQEA 4Z0KB 4BTTA 3SW2A 1FAKL 1LK9A 3SOVA 3BT1A 5JBCE 2RNLA 2JKHL 3N8YB 2WPIE 2W2PE 3SOQA 1YO8A 1DQBA 5COXA 1HREA 2WPHE 1IGXA 4Y79B 4RRXA 3V64C
chains in the Genus database with same CATH topology
1IQHL 3OLUA 1IGZA 3POYA 4JZEL 2FZZL 1FJSL 1EGFA 1IQIL 2P3FL 4O02B 1EZQB 2BQ6A 3BPSE 5L2YL 2XC5L 3M36L 2G00L 1WHFA 4Y6DB 3GCWE 3LAQA 1CCFA 3HO3A 1G2LB 5L2ZL 2XBYL 2FLBL 2P93L 4ZH8B 1GK5A 2VJ3A 2AYLA 2Q1JB 2VVCK 2BMGA 3TBDA 1IP0A 4YT7L 2NPRA 4CSYA 1HT5A 2H9EC 2UWLB 4ZAEB 5JBAE 3N8ZA 4BTUA 2Y5HL 5JVYA 3DEMA 2W2QE 3CS7L 4JYUL 3C9AC 5KN5C 1CCVA 1EBVA 3NT1A 3N8XA 3ASIA 2K2TA 4RUTA 2VWOL 1EPIA 3TGFA 4ISIL 1ZAQA 3Q7DA 4X8UL 2WPKE 4JZDL 1CEJA 2P3TA 1IJQA 2W3IB 2W2OE 4RRWA 2K2SB 4RS0A 4O1ZA 5CKQA 2TGFA 1P0SL 3V65B 2WPLE 1LMJA 4MMZB 4LMFA 2FD6A 3P5BL 3F1SB 1LMMA 1XFEA 2DDUA 4BTIA 1DIYA 2YGQA 4D0FA 2RA0L 1HT8A 1HAEA 1PRHA 1FSBA 4NGAL 5JBBE 2VWNL 1SZBA 1NFYB 1IVOC 5K0HB 2XBWL 1AUTL 1MQ6L 1WHEA 2M74A 5JVZA 1CVUA 1PFXL 2BOUA 3ZYJB 3RR3A 1P9JA 4CUDA 2OYUP 1NPEB 2W3KB 1KLOA 3Q3KB 4OTJA 3ENSA 4JZFL 2W26B 2P26A 1FF7A 1NFXB 2PHBB 2VH0B 1IQLL 2BQ7A 4XBMA 1LPGA 2UWOB 5E8DA 5IKRA 3FBYA 1IQFL 5IKTA 1DX5I 1IOEL 5IKVA 1EMNA 1G1RA 1N7DA 3KCGL 3NJPC 4A94C 3HS7A 4BXSA 1F0SB 1EAIC 1G1TA 1EQHA 2J2UB 1G1QA 4OTYA 4ZXXL 2FLGA 3NTGA 1NFWB 6COXA 3R05A 3PGHA 1FFMA 1EMOA 4YT6L 1Z6CA 2VH6B 3N8VA 1FAXL 1APOA 2KNIA 2Y38A 1IQGL 1HCGB 1HZ8A 4D90A 4ZHAB 1KLJL 1EPGA 2J34B 1F0RB 1JV2B 2WFTA 3ELAL 2OYEP 1K36A 1JBUL 3FFGL 1RFNB 4LORA 4A7IA 5CKNA 1HRFA 1XKAL 2W2NE 3KQEL 3LTGD 2WFXB 1YGCL 1UZQA 1C5MF 1W8BL 3CENL 2BZ6L 4G1MB 3ZYIB 1DDXA 4M11A 5F19A 4X8VL 2D1JB 5JW1A 4XL1A 1I0UA 4BXWA 3KK6A 3KQBL 1EPJA 4Z0LA 3HS5A 3BT2A 2I9AA 1CVWL 2WG4B 1LPKA 1UZPA 2EI6B 4E1GA 1WU1B 2F9BL 2H9EL 3CFWA 1B9WA 1ATDA 1LPZA 2VWLL 1HAFA 1TOZA 4CUEA 3LN1A 3H5CB 1UZKA 1OB1C 5FDQA 2WZPP 1N1IA 2W2ME 1V3XB 1MQ5L 1TPGA 3GISX 1IQML 2UWPB 2MHPA 2B7DL 1NT0A 3N8YA 1A3PA 2VVVL 2P95L 3GCXE 2Y5GL 1MOXC 4Y71B 3MQEA 2BOHA 3TK6B 4RRYA 1Q4GA 3S6XA 4AQTA 1DVAL 1NFUB 1M1XB 1U8CB 3QCWA 2VWMK 1L3YA 2Y5FL 1W7XL 3QMOA 3IITB 3KQDL 2KB9A 2J38B 1KLIL 3FCSB 3M37L 1IQJL 2EI7B 2P16L 2WYJB 2Y7ZB 3ZYGA 1YUKB 3KRKA 2XBXL 3SOBB 3KQCL 2ADXA 4JYVL 4TGFA 4XLWA 1EQGA 3U7UG 1ATEA 1ATBA 1TLEA 2BQWA 3MDLA 1F7MA 4MMXB 2Y82B 2RHPA 4NG9L 1BF9A 3HPTA 5JB8E 4BDXA 4Y76B 1Z6EL 2BOXA 3LTFB 2W86A 2Y81B 1HJ7A 2WPME 1NQLB 2Y7XB 2MGPA 3IJEB 2BO2A 4FM5A 3U73A 4BDWA 2KV4A 1EPHA 3TZIA 3EGFA 1IOXA 2J95B 3TH3L 4ISHL 1PTHA 2PUQL 4X8SL 4Z6AL 1O5DL 1KSNB 3HS6A 3HO5A 3N8WA 2XC0L 1IQKL 4CUFA 4ZXYL 3LC5B 2GD4A 4COXA 2KL7A 3NTBA 2J94B 2J4IB 4NA9L 1X7AL 4Y7BB 2FLRL 2CJIB 2XC4L 2Y80B 1G1SA 1PXXA 4RRZA 2YGOA 2P3FN 3LC3B 4C16A 3HO4A 2YGPA 4YZUB 3N8WB 1XDTR 1APQA 2P94L 4PH9A 3LIWB 2BOKL 1K37A 2EI8B 2WYGB 4D0EA 1ADXA 2WG3C 3LN0A 1CX2A 1KIGL 1HX2A 5KIRA 5L30L 1QFKL 2P28B 5IKQA 1F7EA 3CA7A 1G2MB 3OLTA 5CKMA 2PR3B 1PGEA 1YUFA 1J9CL 2MGRA 2VVUL 1LQDA 1URKA 5CISA 1U67A 1COUA 2XBVL 1XKBA 1FE2A 3QH0A 4M10A 1NZIA 5F1AA 3F6UL 1IQEL 2WPJE 1ATAA 2P3UA 1JL9A 4Y7AB 1L5GB 5EGMB 5JB9E 3KL6B 4X8TL 3TK5B 3K9XA 5I46L 4MMYB 1UZJA 2I9BA 1YUGA 1IQNL 1CQEA 4Z0KB 4BTTA 3SW2A 1FAKL 3SOVA 3BT1A 5JBCE 2RNLA 2JKHL 3N8YB 2WPIE 2W2PE 3SOQA 1YO8A 1DQBA 5COXA 1HREA 2WPHE 1IGXA 4Y79B 4RRXA 3V64C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IQH L;  3OLU A;  1IGZ A;  3POY A;  4JZE L;  2FZZ L;  1FJS L;  1EGF A;  1IQI L;  2P3F L;  4O02 B;  1EZQ B;  2BQ6 A;  3BPS E;  5L2Y L;  2XC5 L;  3M36 L;  2G00 L;  1WHF A;  4Y6D B;  3GCW E;  3LAQ A;  1CCF A;  3HO3 A;  1G2L B;  5L2Z L;  2XBY L;  2FLB L;  2P93 L;  4ZH8 B;  1GK5 A;  2VJ3 A;  2AYL A;  2Q1J B;  2VVC K;  2BMG A;  3TBD A;  1IP0 A;  4YT7 L;  2NPR A;  4CSY A;  1HT5 A;  2UWL B;  4ZAE B;  5JBA E;  3N8Z A;  4BTU A;  2Y5H L;  5JVY A;  3DEM A;  2W2Q E;  3CS7 L;  4JYU L;  3C9A C;  5KN5 C;  1CCV A;  1EBV A;  3NT1 A;  3N8X A;  3ASI A;  2K2T A;  4RUT A;  2VWO L;  1EPI A;  3TGF A;  4ISI L;  1ZAQ A;  3Q7D A;  4X8U L;  2WPK E;  4JZD L;  1CEJ A;  2P3T A;  1IJQ A;  2W3I B;  2W2O E;  4RRW A;  2K2S B;  4RS0 A;  4O1Z A;  5CKQ A;  2TGF A;  1P0S L;  3V65 B;  2WPL E;  1LMJ A;  4MMZ B;  4LMF A;  2FD6 A;  3P5B L;  3F1S B;  1XFE A;  2DDU A;  4BTI A;  1DIY A;  4D0F A;  2RA0 L;  1HT8 A;  1HAE A;  1PRH A;  1FSB A;  4NGA L;  5JBB E;  2VWN L;  1SZB A;  1NFY B;  1IVO C;  5K0H B;  2XBW L;  1AUT L;  1MQ6 L;  1WHE A;  2M74 A;  5JVZ A;  1CVU A;  1PFX L;  2BOU A;  3ZYJ B;  3RR3 A;  1P9J A;  4CUD A;  2OYU P;  1NPE B;  2W3K B;  1KLO A;  3Q3K B;  4OTJ A;  3ENS A;  4JZF L;  2W26 B;  2P26 A;  1FF7 A;  1NFX B;  2PHB B;  2VH0 B;  1IQL L;  2BQ7 A;  4XBM A;  1LPG A;  2UWO B;  5E8D A;  5IKR A;  3FBY A;  1IQF L;  5IKT A;  1DX5 I;  1IOE L;  5IKV A;  1EMN A;  1G1R A;  1N7D A;  3KCG L;  3NJP C;  3HS7 A;  4BXS A;  1F0S B;  1EAI C;  1G1T A;  1EQH A;  2J2U B;  1G1Q A;  4OTY A;  4ZXX L;  2FLG A;  3NTG A;  1NFW B;  6COX A;  3R05 A;  3PGH A;  1FFM A;  1EMO A;  4YT6 L;  1Z6C A;  2VH6 B;  3N8V A;  1FAX L;  1APO A;  2Y38 A;  1IQG L;  1HCG B;  1HZ8 A;  4D90 A;  4ZHA B;  1KLJ L;  1EPG A;  2J34 B;  1F0R B;  1JV2 B;  2WFT A;  3ELA L;  2OYE P;  1K36 A;  1JBU L;  3FFG L;  1RFN B;  4LOR A;  4A7I A;  5CKN A;  1HRF A;  1XKA L;  2W2N E;  3KQE L;  3LTG D;  2WFX B;  1YGC L;  1UZQ A;  1C5M F;  1W8B L;  3CEN L;  2BZ6 L;  4G1M B;  3ZYI B;  1DDX A;  4M11 A;  5F19 A;  4X8V L;  2D1J B;  5JW1 A;  4XL1 A;  1I0U A;  4BXW A;  3KK6 A;  3KQB L;  1EPJ A;  4Z0L A;  3HS5 A;  3BT2 A;  2I9A A;  1CVW L;  2WG4 B;  1LPK A;  1UZP A;  2EI6 B;  4E1G A;  1WU1 B;  2F9B L;  2H9E L;  3CFW A;  1B9W A;  1ATD A;  1LPZ A;  2VWL L;  1HAF A;  1TOZ A;  4CUE A;  3LN1 A;  3H5C B;  1UZK A;  1OB1 C;  5FDQ A;  1N1I A;  2W2M E;  1V3X B;  1MQ5 L;  1TPG A;  3GIS X;  1IQM L;  2UWP B;  2MHP A;  2B7D L;  1NT0 A;  3N8Y A;  1A3P A;  2VVV L;  2P95 L;  3GCX E;  2Y5G L;  1MOX C;  4Y71 B;  3MQE A;  2BOH A;  3TK6 B;  4RRY A;  1Q4G A;  4AQT A;  1DVA L;  1NFU B;  1M1X B;  1U8C B;  3QCW A;  2VWM K;  1L3Y A;  2Y5F L;  1W7X L;  3QMO A;  3IIT B;  3KQD L;  2KB9 A;  2J38 B;  1KLI L;  3FCS B;  3M37 L;  1IQJ L;  2EI7 B;  2P16 L;  2WYJ B;  2Y7Z B;  3ZYG A;  1YUK B;  3KRK A;  2XBX L;  3SOB B;  3KQC L;  2ADX A;  4JYV L;  4TGF A;  4XLW A;  1EQG A;  3U7U G;  1ATE A;  1ATB A;  1TLE A;  2BQW A;  3MDL A;  1F7M A;  4MMX B;  2Y82 B;  2RHP A;  4NG9 L;  1BF9 A;  3HPT A;  5JB8 E;  4BDX A;  4Y76 B;  1Z6E L;  2BOX A;  3LTF B;  2W86 A;  2Y81 B;  1HJ7 A;  2WPM E;  1NQL B;  2Y7X B;  2MGP A;  3IJE B;  2BO2 A;  4FM5 A;  3U73 A;  4BDW A;  2KV4 A;  1EPH A;  3TZI A;  3EGF A;  1IOX A;  2J95 B;  3TH3 L;  4ISH L;  1PTH A;  2PUQ L;  4X8S L;  4Z6A L;  1O5D L;  1KSN B;  3HS6 A;  3HO5 A;  3N8W A;  2XC0 L;  1IQK L;  4CUF A;  4ZXY L;  3LC5 B;  2GD4 A;  4COX A;  2KL7 A;  3NTB A;  2J94 B;  2J4I B;  4NA9 L;  1X7A L;  4Y7B B;  2FLR L;  2CJI B;  2XC4 L;  2Y80 B;  1G1S A;  1PXX A;  4RRZ A;  2YGO A;  2P3F N;  3LC3 B;  4C16 A;  3HO4 A;  2YGP A;  4YZU B;  3N8W B;  1XDT R;  1APQ A;  2P94 L;  4PH9 A;  3LIW B;  2BOK L;  1K37 A;  2EI8 B;  2WYG B;  4D0E A;  1ADX A;  2WG3 C;  3LN0 A;  1CX2 A;  1KIG L;  1HX2 A;  5KIR A;  5L30 L;  1QFK L;  2P28 B;  5IKQ A;  1F7E A;  3CA7 A;  1G2M B;  3OLT A;  5CKM A;  2PR3 B;  1PGE A;  1YUF A;  1J9C L;  2MGR A;  2VVU L;  1LQD A;  1URK A;  5CIS A;  1U67 A;  1COU A;  2XBV L;  1XKB A;  1FE2 A;  3QH0 A;  4M10 A;  1NZI A;  5F1A A;  3F6U L;  1IQE L;  2WPJ E;  1ATA A;  2P3U A;  1JL9 A;  4Y7A B;  1L5G B;  5EGM B;  5JB9 E;  3KL6 B;  4X8T L;  3TK5 B;  3K9X A;  5I46 L;  4MMY B;  1UZJ A;  2I9B A;  1YUG A;  1IQN L;  1CQE A;  4Z0K B;  4BTT A;  3SW2 A;  1FAK L;  3SOV A;  3BT1 A;  5JBC E;  2RNL A;  2JKH L;  3N8Y B;  2WPI E;  2W2P E;  3SOQ A;  1YO8 A;  1DQB A;  5COX A;  1HRE A;  2WPH E;  1IGX A;  4Y79 B;  4RRX A;  3V64 C; 
#chains in the Genus database with same CATH topology
 1IQH L;  3OLU A;  1IGZ A;  3POY A;  4JZE L;  2FZZ L;  1FJS L;  1EGF A;  1IQI L;  2P3F L;  4O02 B;  1EZQ B;  2BQ6 A;  3BPS E;  2BSF A;  5L2Y L;  2XC5 L;  3M36 L;  2HOR A;  2G00 L;  1WHF A;  4Y6D B;  3GCW E;  3LAQ A;  1CCF A;  3HO3 A;  1G2L B;  5L2Z L;  2XBY L;  2FLB L;  2P93 L;  4ZH8 B;  1GK5 A;  2VJ3 A;  2AYL A;  2Q1J B;  2VVC K;  2BMG A;  3TBD A;  1IP0 A;  4YT7 L;  2NPR A;  4CSY A;  1HT5 A;  2H9E C;  2UWL B;  4ZAE B;  5JBA E;  3N8Z A;  4BTU A;  2Y5H L;  5JVY A;  3DEM A;  2W2Q E;  3CS7 L;  4JYU L;  3C9A C;  5KN5 C;  1CCV A;  1EBV A;  3NT1 A;  3N8X A;  1V1H A;  2K2T A;  3ASI A;  4RUT A;  2VWO L;  1EPI A;  3TGF A;  4ISI L;  1ZAQ A;  3Q7D A;  4X8U L;  2WPK E;  4JZD L;  1CEJ A;  2P3T A;  1IJQ A;  2W3I B;  2W2O E;  4RRW A;  2K2S B;  4RS0 A;  4O1Z A;  5CKQ A;  2TGF A;  1P0S L;  3V65 B;  2WPL E;  1LMJ A;  4MMZ B;  4LMF A;  2FD6 A;  3P5B L;  3F1S B;  1LMM A;  1XFE A;  2DDU A;  4BTI A;  1DIY A;  2YGQ A;  4D0F A;  2RA0 L;  1HT8 A;  1HAE A;  1PRH A;  1FSB A;  4NGA L;  5JBB E;  2VWN L;  1SZB A;  1NFY B;  1IVO C;  5K0H B;  2XBW L;  1AUT L;  1MQ6 L;  1WHE A;  2M74 A;  5JVZ A;  1CVU A;  1PFX L;  2BOU A;  3ZYJ B;  3RR3 A;  1P9J A;  4CUD A;  2OYU P;  4GU3 A;  1NPE B;  2W3K B;  1KLO A;  3Q3K B;  4OTJ A;  3ENS A;  4JZF L;  1V1I A;  2W26 B;  2P26 A;  1FF7 A;  1NFX B;  2PHB B;  2VH0 B;  1IQL L;  2BQ7 A;  4XBM A;  1LPG A;  2UWO B;  5E8D A;  5IKR A;  3FBY A;  1IQF L;  5IKT A;  1DX5 I;  1IOE L;  5IKV A;  1EMN A;  1G1R A;  1N7D A;  3KCG L;  3NJP C;  4A94 C;  3HS7 A;  4BXS A;  1F0S B;  1EAI C;  1G1T A;  1EQH A;  2J2U B;  1G1Q A;  4OTY A;  4ZXX L;  2FLG A;  3NTG A;  1NFW B;  6COX A;  3R05 A;  3PGH A;  1FFM A;  1EMO A;  4YT6 L;  1Z6C A;  2VH6 B;  3N8V A;  1FAX L;  1APO A;  2KNI A;  2Y38 A;  1IQG L;  1HCG B;  1HZ8 A;  4D90 A;  4ZHA B;  1KLJ L;  1EPG A;  2J34 B;  1F0R B;  1JV2 B;  2WFT A;  2VRS A;  3ELA L;  2OYE P;  1K36 A;  1JBU L;  3FFG L;  1RFN B;  4LOR A;  4A7I A;  5CKN A;  1HRF A;  1XKA L;  2HOX A;  2W2N E;  3KQE L;  3LTG D;  2WFX B;  1YGC L;  1UZQ A;  1C5M F;  1W8B L;  3CEN L;  2BZ6 L;  4G1M B;  3ZYI B;  1DDX A;  4M11 A;  5F19 A;  4X8V L;  2D1J B;  5JW1 A;  4XL1 A;  1I0U A;  4BXW A;  3KK6 A;  3KQB L;  1EPJ A;  4Z0L A;  3HS5 A;  3BT2 A;  2I9A A;  1CVW L;  2WG4 B;  1LPK A;  2BT8 A;  1UZP A;  2EI6 B;  4E1G A;  1WU1 B;  2F9B L;  2H9E L;  3CFW A;  1B9W A;  1ATD A;  1LPZ A;  2VWL L;  1HAF A;  1TOZ A;  4CUE A;  3LN1 A;  3H5C B;  1UZK A;  1OB1 C;  5FDQ A;  2WZP P;  1N1I A;  2W2M E;  1V3X B;  1MQ5 L;  1TPG A;  3GIS X;  1IQM L;  2UWP B;  2MHP A;  2B7D L;  1NT0 A;  3N8Y A;  1A3P A;  2VVV L;  2P95 L;  3GCX E;  2Y5G L;  1MOX C;  4Y71 B;  3MQE A;  2BOH A;  3TK6 B;  4RRY A;  1Q4G A;  3S6X A;  4AQT A;  1DVA L;  1NFU B;  1M1X B;  1U8C B;  3QCW A;  2VWM K;  1L3Y A;  2Y5F L;  1W7X L;  3QMO A;  4GU4 A;  3IIT B;  3KQD L;  2KB9 A;  2J38 B;  1KLI L;  3FCS B;  3M37 L;  1IQJ L;  2EI7 B;  2P16 L;  2WYJ B;  2Y7Z B;  3ZYG A;  1YUK B;  3KRK A;  2XBX L;  3SOB B;  3KQC L;  2ADX A;  4JYV L;  4TGF A;  4XLW A;  1EQG A;  3U7U G;  1ATE A;  1ATB A;  1TLE A;  2BQW A;  3MDL A;  1F7M A;  4MMX B;  2Y82 B;  2RHP A;  4NG9 L;  1BF9 A;  3HPT A;  5JB8 E;  4BDX A;  4Y76 B;  1Z6E L;  2BOX A;  3LTF B;  2W86 A;  2Y81 B;  1HJ7 A;  2WPM E;  1NQL B;  2Y7X B;  2MGP A;  3IJE B;  2BO2 A;  4FM5 A;  3U73 A;  4BDW A;  2KV4 A;  1EPH A;  3TZI A;  3EGF A;  1IOX A;  2J95 B;  3TH3 L;  4ISH L;  1PTH A;  2PUQ L;  4X8S L;  4Z6A L;  1O5D L;  1KSN B;  3HS6 A;  3HO5 A;  3N8W A;  2XC0 L;  1IQK L;  1QIU A;  4CUF A;  4ZXY L;  3LC5 B;  1KKE A;  2GD4 A;  2JJL A;  4COX A;  2KL7 A;  3NTB A;  2J94 B;  2J4I B;  4NA9 L;  1X7A L;  4Y7B B;  2FLR L;  2CJI B;  2XC4 L;  2Y80 B;  1G1S A;  1PXX A;  4RRZ A;  2YGO A;  2P3F N;  3LC3 B;  4C16 A;  3HO4 A;  2YGP A;  4YZU B;  3N8W B;  1XDT R;  1APQ A;  2P94 L;  4PH9 A;  3LIW B;  2BOK L;  1K37 A;  2EI8 B;  2WYG B;  4D0E A;  1ADX A;  2WG3 C;  3LN0 A;  1CX2 A;  1KIG L;  1HX2 A;  5KIR A;  5L30 L;  1QFK L;  2BT7 A;  2P28 B;  5IKQ A;  1F7E A;  3CA7 A;  1G2M B;  3OLT A;  5CKM A;  2PR3 B;  1PGE A;  1YUF A;  1J9C L;  2MGR A;  2VVU L;  1LQD A;  1URK A;  5CIS A;  1U67 A;  1COU A;  2XBV L;  1XKB A;  1FE2 A;  3QH0 A;  4M10 A;  1NZI A;  5F1A A;  3F6U L;  1IQE L;  2WPJ E;  1ATA A;  2P3U A;  1JL9 A;  4Y7A B;  1L5G B;  5EGM B;  5JB9 E;  3KL6 B;  4X8T L;  3TK5 B;  3K9X A;  5I46 L;  4MMY B;  1UZJ A;  2I9B A;  1YUG A;  1IQN L;  1CQE A;  4Z0K B;  4BTT A;  3SW2 A;  1FAK L;  1LK9 A;  3SOV A;  3BT1 A;  5JBC E;  2RNL A;  2JKH L;  3N8Y B;  2WPI E;  2W2P E;  3SOQ A;  1YO8 A;  1DQB A;  5COX A;  1HRE A;  2WPH E;  1IGX A;  4Y79 B;  4RRX A;  3V64 C; 
#chains in the Genus database with same CATH homology
 1IQH L;  3OLU A;  1IGZ A;  3POY A;  4JZE L;  2FZZ L;  1FJS L;  1EGF A;  1IQI L;  2P3F L;  4O02 B;  1EZQ B;  2BQ6 A;  3BPS E;  5L2Y L;  2XC5 L;  3M36 L;  2G00 L;  1WHF A;  4Y6D B;  3GCW E;  3LAQ A;  1CCF A;  3HO3 A;  1G2L B;  5L2Z L;  2XBY L;  2FLB L;  2P93 L;  4ZH8 B;  1GK5 A;  2VJ3 A;  2AYL A;  2Q1J B;  2VVC K;  2BMG A;  3TBD A;  1IP0 A;  4YT7 L;  2NPR A;  4CSY A;  1HT5 A;  2H9E C;  2UWL B;  4ZAE B;  5JBA E;  3N8Z A;  4BTU A;  2Y5H L;  5JVY A;  3DEM A;  2W2Q E;  3CS7 L;  4JYU L;  3C9A C;  5KN5 C;  1CCV A;  1EBV A;  3NT1 A;  3N8X A;  3ASI A;  2K2T A;  4RUT A;  2VWO L;  1EPI A;  3TGF A;  4ISI L;  1ZAQ A;  3Q7D A;  4X8U L;  2WPK E;  4JZD L;  1CEJ A;  2P3T A;  1IJQ A;  2W3I B;  2W2O E;  4RRW A;  2K2S B;  4RS0 A;  4O1Z A;  5CKQ A;  2TGF A;  1P0S L;  3V65 B;  2WPL E;  1LMJ A;  4MMZ B;  4LMF A;  2FD6 A;  3P5B L;  3F1S B;  1LMM A;  1XFE A;  2DDU A;  4BTI A;  1DIY A;  2YGQ A;  4D0F A;  2RA0 L;  1HT8 A;  1HAE A;  1PRH A;  1FSB A;  4NGA L;  5JBB E;  2VWN L;  1SZB A;  1NFY B;  1IVO C;  5K0H B;  2XBW L;  1AUT L;  1MQ6 L;  1WHE A;  2M74 A;  5JVZ A;  1CVU A;  1PFX L;  2BOU A;  3ZYJ B;  3RR3 A;  1P9J A;  4CUD A;  2OYU P;  1NPE B;  2W3K B;  1KLO A;  3Q3K B;  4OTJ A;  3ENS A;  4JZF L;  2W26 B;  2P26 A;  1FF7 A;  1NFX B;  2PHB B;  2VH0 B;  1IQL L;  2BQ7 A;  4XBM A;  1LPG A;  2UWO B;  5E8D A;  5IKR A;  3FBY A;  1IQF L;  5IKT A;  1DX5 I;  1IOE L;  5IKV A;  1EMN A;  1G1R A;  1N7D A;  3KCG L;  3NJP C;  4A94 C;  3HS7 A;  4BXS A;  1F0S B;  1EAI C;  1G1T A;  1EQH A;  2J2U B;  1G1Q A;  4OTY A;  4ZXX L;  2FLG A;  3NTG A;  1NFW B;  6COX A;  3R05 A;  3PGH A;  1FFM A;  1EMO A;  4YT6 L;  1Z6C A;  2VH6 B;  3N8V A;  1FAX L;  1APO A;  2KNI A;  2Y38 A;  1IQG L;  1HCG B;  1HZ8 A;  4D90 A;  4ZHA B;  1KLJ L;  1EPG A;  2J34 B;  1F0R B;  1JV2 B;  2WFT A;  3ELA L;  2OYE P;  1K36 A;  1JBU L;  3FFG L;  1RFN B;  4LOR A;  4A7I A;  5CKN A;  1HRF A;  1XKA L;  2W2N E;  3KQE L;  3LTG D;  2WFX B;  1YGC L;  1UZQ A;  1C5M F;  1W8B L;  3CEN L;  2BZ6 L;  4G1M B;  3ZYI B;  1DDX A;  4M11 A;  5F19 A;  4X8V L;  2D1J B;  5JW1 A;  4XL1 A;  1I0U A;  4BXW A;  3KK6 A;  3KQB L;  1EPJ A;  4Z0L A;  3HS5 A;  3BT2 A;  2I9A A;  1CVW L;  2WG4 B;  1LPK A;  1UZP A;  2EI6 B;  4E1G A;  1WU1 B;  2F9B L;  2H9E L;  3CFW A;  1B9W A;  1ATD A;  1LPZ A;  2VWL L;  1HAF A;  1TOZ A;  4CUE A;  3LN1 A;  3H5C B;  1UZK A;  1OB1 C;  5FDQ A;  2WZP P;  1N1I A;  2W2M E;  1V3X B;  1MQ5 L;  1TPG A;  3GIS X;  1IQM L;  2UWP B;  2MHP A;  2B7D L;  1NT0 A;  3N8Y A;  1A3P A;  2VVV L;  2P95 L;  3GCX E;  2Y5G L;  1MOX C;  4Y71 B;  3MQE A;  2BOH A;  3TK6 B;  4RRY A;  1Q4G A;  3S6X A;  4AQT A;  1DVA L;  1NFU B;  1M1X B;  1U8C B;  3QCW A;  2VWM K;  1L3Y A;  2Y5F L;  1W7X L;  3QMO A;  3IIT B;  3KQD L;  2KB9 A;  2J38 B;  1KLI L;  3FCS B;  3M37 L;  1IQJ L;  2EI7 B;  2P16 L;  2WYJ B;  2Y7Z B;  3ZYG A;  1YUK B;  3KRK A;  2XBX L;  3SOB B;  3KQC L;  2ADX A;  4JYV L;  4TGF A;  4XLW A;  1EQG A;  3U7U G;  1ATE A;  1ATB A;  1TLE A;  2BQW A;  3MDL A;  1F7M A;  4MMX B;  2Y82 B;  2RHP A;  4NG9 L;  1BF9 A;  3HPT A;  5JB8 E;  4BDX A;  4Y76 B;  1Z6E L;  2BOX A;  3LTF B;  2W86 A;  2Y81 B;  1HJ7 A;  2WPM E;  1NQL B;  2Y7X B;  2MGP A;  3IJE B;  2BO2 A;  4FM5 A;  3U73 A;  4BDW A;  2KV4 A;  1EPH A;  3TZI A;  3EGF A;  1IOX A;  2J95 B;  3TH3 L;  4ISH L;  1PTH A;  2PUQ L;  4X8S L;  4Z6A L;  1O5D L;  1KSN B;  3HS6 A;  3HO5 A;  3N8W A;  2XC0 L;  1IQK L;  4CUF A;  4ZXY L;  3LC5 B;  2GD4 A;  4COX A;  2KL7 A;  3NTB A;  2J94 B;  2J4I B;  4NA9 L;  1X7A L;  4Y7B B;  2FLR L;  2CJI B;  2XC4 L;  2Y80 B;  1G1S A;  1PXX A;  4RRZ A;  2YGO A;  2P3F N;  3LC3 B;  4C16 A;  3HO4 A;  2YGP A;  4YZU B;  3N8W B;  1XDT R;  1APQ A;  2P94 L;  4PH9 A;  3LIW B;  2BOK L;  1K37 A;  2EI8 B;  2WYG B;  4D0E A;  1ADX A;  2WG3 C;  3LN0 A;  1CX2 A;  1KIG L;  1HX2 A;  5KIR A;  5L30 L;  1QFK L;  2P28 B;  5IKQ A;  1F7E A;  3CA7 A;  1G2M B;  3OLT A;  5CKM A;  2PR3 B;  1PGE A;  1YUF A;  1J9C L;  2MGR A;  2VVU L;  1LQD A;  1URK A;  5CIS A;  1U67 A;  1COU A;  2XBV L;  1XKB A;  1FE2 A;  3QH0 A;  4M10 A;  1NZI A;  5F1A A;  3F6U L;  1IQE L;  2WPJ E;  1ATA A;  2P3U A;  1JL9 A;  4Y7A B;  1L5G B;  5EGM B;  5JB9 E;  3KL6 B;  4X8T L;  3TK5 B;  3K9X A;  5I46 L;  4MMY B;  1UZJ A;  2I9B A;  1YUG A;  1IQN L;  1CQE A;  4Z0K B;  4BTT A;  3SW2 A;  1FAK L;  3SOV A;  3BT1 A;  5JBC E;  2RNL A;  2JKH L;  3N8Y B;  2WPI E;  2W2P E;  3SOQ A;  1YO8 A;  1DQB A;  5COX A;  1HRE A;  2WPH E;  1IGX A;  4Y79 B;  4RRX A;  3V64 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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