3EBNA

A special dimerization of sars-cov main protease c-terminal domain due to domain-swapping
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
100
structure length
100
Chain Sequence
TTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title C-terminal domain of SARS-CoV main protease can form a 3D domain-swapped dimer
pubmed doi rcsb
molecule tags Hydrolase
source organism Sars coronavirus
molecule keywords Replicase polyprotein 1ab
total genus 24
structure length 100
sequence length 100
chains with identical sequence B, C, D
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2008-08-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1840.10 Mainly Alpha Orthogonal Bundle main proteinase (3clpro) structure, domain 3 main proteinase (3clpro) structure, domain 3 3ebnA00
2YNBA 1UJ1A 3EBNA 5HYOA 3EA8A 3TNSA 2PWXA 4RSPA 4MDSA 3F9GA 2A5IA 2V6NA 2Q6DA 3VB7A 3SNBA 2K7XA 4TWWA 2A5AA 3VB6A 2YNAA 2A5KA 2Z94A 4TWYA 3IWMA 2C3SA 2Z9LA 3EA9A 4WY3A 3M3TA 3F9EA 1UK4A 3SNAA 2Z9JA 1WOFA 3SNDA 1LVOA 1Z1IA 2QIQA 2ZU4A 3AW1A 2ZU5A 3TLOA 3TNTA 3V3MA 4WMDA 3VB3A 4WMFA 2GZ9A 1P9UA 4YOGA 5GWZA 2DUCA 4YOIA 2OP9A 4YOJA 2Z9GA 2BX4A 2GX4A 2GZ7A 3VB5A 3F9FA 4F49A 2LIZA 3EAJA 4YLUA 2Q6GA 3VB4A 3SN8A 2BX3A 3AW0A 2Z3EA 2VJ1A 5C3NA 3SNEA 2ALVA 2HOBA 4YO9A 3F9HA 2GT8A 3D23A 2GZ8A 2QC2A 3FZDA 2AMQA 2Z9KA 1UK3A 1P9SA 2Z3DA 2AMPA 4WMEA 2ZU2A 3AVZA 1Q2WA 2GTBA 5B6OA 5C5NA 3SNCA 2Z3CA 2AMDA 3TIUA 1UK2A 3E91A 1Z1JA 2GT7A 3EA7A 2QCYA 3M3VA 3SZNA 4ZUHA 2D2DA 3D62A 4HI3A 4ZROA 4XFQA 5EU8A 2H2ZA 3ATWA 3TITA 2Q6FA 5C5OA 3M3SA
chains in the Genus database with same CATH superfamily
2YNBA 1UJ1A 3EBNA 5HYOA 3EA8A 3TNSA 2PWXA 4RSPA 4MDSA 3F9GA 2A5IA 2V6NA 2Q6DA 3VB7A 3SNBA 2K7XA 4TWWA 2A5AA 3VB6A 2YNAA 2A5KA 2Z94A 4TWYA 3IWMA 2C3SA 2Z9LA 3EA9A 4WY3A 3M3TA 3F9EA 1UK4A 3SNAA 2Z9JA 1WOFA 3SNDA 1LVOA 1Z1IA 2QIQA 2ZU4A 3AW1A 2ZU5A 3TLOA 3TNTA 3V3MA 4WMDA 3VB3A 4WMFA 2GZ9A 1P9UA 4YOGA 5GWZA 2DUCA 4YOIA 2OP9A 4YOJA 2Z9GA 2BX4A 2GX4A 2GZ7A 3VB5A 3F9FA 4F49A 2LIZA 3EAJA 4YLUA 2Q6GA 3VB4A 3SN8A 2BX3A 3AW0A 2Z3EA 2VJ1A 5C3NA 3SNEA 2ALVA 2HOBA 4YO9A 3F9HA 2GT8A 3D23A 2GZ8A 2QC2A 3FZDA 2AMQA 2Z9KA 1UK3A 1P9SA 2Z3DA 2AMPA 4WMEA 2ZU2A 3AVZA 1Q2WA 2GTBA 5B6OA 5C5NA 3SNCA 2Z3CA 2AMDA 3TIUA 1UK2A 3E91A 1Z1JA 2GT7A 3EA7A 2QCYA 3M3VA 3SZNA 4ZUHA 2D2DA 3D62A 4HI3A 4ZROA 4XFQA 5EU8A 2H2ZA 3ATWA 3TITA 2Q6FA 5C5OA 3M3SA
chains in the Genus database with same CATH topology
2YNBA 1UJ1A 3EBNA 5HYOA 3EA8A 3TNSA 2PWXA 4RSPA 4MDSA 3F9GA 2A5IA 2V6NA 2Q6DA 3VB7A 3SNBA 2K7XA 4TWWA 2A5AA 3VB6A 2YNAA 2A5KA 2Z94A 4TWYA 3IWMA 2C3SA 2Z9LA 3EA9A 4WY3A 3M3TA 3F9EA 1UK4A 3SNAA 2Z9JA 1WOFA 3SNDA 1LVOA 1Z1IA 2QIQA 2ZU4A 3AW1A 2ZU5A 3TLOA 3TNTA 3V3MA 4WMDA 3VB3A 4WMFA 2GZ9A 1P9UA 4YOGA 5GWZA 2DUCA 4YOIA 2OP9A 4YOJA 2Z9GA 2BX4A 2GX4A 2GZ7A 3VB5A 3F9FA 4F49A 2LIZA 3EAJA 4YLUA 2Q6GA 3VB4A 3SN8A 2BX3A 3AW0A 2Z3EA 2VJ1A 5C3NA 3SNEA 2ALVA 2HOBA 4YO9A 3F9HA 2GT8A 3D23A 2GZ8A 2QC2A 3FZDA 2AMQA 2Z9KA 1UK3A 1P9SA 2Z3DA 2AMPA 4WMEA 2ZU2A 3AVZA 1Q2WA 2GTBA 5B6OA 5C5NA 3SNCA 2Z3CA 2AMDA 3TIUA 1UK2A 3E91A 1Z1JA 2GT7A 3EA7A 2QCYA 3M3VA 3SZNA 4ZUHA 2D2DA 3D62A 4HI3A 4ZROA 4XFQA 5EU8A 2H2ZA 3ATWA 3TITA 2Q6FA 5C5OA 3M3SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YNB A;  1UJ1 A;  3EBN A;  5HYO A;  3EA8 A;  3TNS A;  2PWX A;  4RSP A;  4MDS A;  3F9G A;  2A5I A;  2V6N A;  2Q6D A;  3VB7 A;  3SNB A;  2K7X A;  4TWW A;  2A5A A;  3VB6 A;  2YNA A;  2A5K A;  2Z94 A;  4TWY A;  3IWM A;  2C3S A;  2Z9L A;  3EA9 A;  4WY3 A;  3M3T A;  3F9E A;  1UK4 A;  3SNA A;  2Z9J A;  1WOF A;  3SND A;  1LVO A;  1Z1I A;  2QIQ A;  2ZU4 A;  3AW1 A;  2ZU5 A;  3TLO A;  3TNT A;  3V3M A;  4WMD A;  3VB3 A;  4WMF A;  2GZ9 A;  1P9U A;  4YOG A;  5GWZ A;  2DUC A;  4YOI A;  2OP9 A;  4YOJ A;  2Z9G A;  2BX4 A;  2GX4 A;  2GZ7 A;  3VB5 A;  3F9F A;  4F49 A;  2LIZ A;  3EAJ A;  4YLU A;  2Q6G A;  3VB4 A;  3SN8 A;  2BX3 A;  3AW0 A;  2Z3E A;  2VJ1 A;  5C3N A;  3SNE A;  2ALV A;  2HOB A;  4YO9 A;  3F9H A;  2GT8 A;  3D23 A;  2GZ8 A;  2QC2 A;  3FZD A;  2AMQ A;  2Z9K A;  1UK3 A;  1P9S A;  2Z3D A;  2AMP A;  4WME A;  2ZU2 A;  3AVZ A;  1Q2W A;  2GTB A;  5B6O A;  5C5N A;  3SNC A;  2Z3C A;  2AMD A;  3TIU A;  1UK2 A;  3E91 A;  1Z1J A;  2GT7 A;  3EA7 A;  2QCY A;  3M3V A;  3SZN A;  4ZUH A;  2D2D A;  3D62 A;  4HI3 A;  4ZRO A;  4XFQ A;  5EU8 A;  2H2Z A;  3ATW A;  3TIT A;  2Q6F A;  5C5O A;  3M3S A; 
#chains in the Genus database with same CATH topology
 2YNB A;  1UJ1 A;  3EBN A;  5HYO A;  3EA8 A;  3TNS A;  2PWX A;  4RSP A;  4MDS A;  3F9G A;  2A5I A;  2V6N A;  2Q6D A;  3VB7 A;  3SNB A;  2K7X A;  4TWW A;  2A5A A;  3VB6 A;  2YNA A;  2A5K A;  2Z94 A;  4TWY A;  3IWM A;  2C3S A;  2Z9L A;  3EA9 A;  4WY3 A;  3M3T A;  3F9E A;  1UK4 A;  3SNA A;  2Z9J A;  1WOF A;  3SND A;  1LVO A;  1Z1I A;  2QIQ A;  2ZU4 A;  3AW1 A;  2ZU5 A;  3TLO A;  3TNT A;  3V3M A;  4WMD A;  3VB3 A;  4WMF A;  2GZ9 A;  1P9U A;  4YOG A;  5GWZ A;  2DUC A;  4YOI A;  2OP9 A;  4YOJ A;  2Z9G A;  2BX4 A;  2GX4 A;  2GZ7 A;  3VB5 A;  3F9F A;  4F49 A;  2LIZ A;  3EAJ A;  4YLU A;  2Q6G A;  3VB4 A;  3SN8 A;  2BX3 A;  3AW0 A;  2Z3E A;  2VJ1 A;  5C3N A;  3SNE A;  2ALV A;  2HOB A;  4YO9 A;  3F9H A;  2GT8 A;  3D23 A;  2GZ8 A;  2QC2 A;  3FZD A;  2AMQ A;  2Z9K A;  1UK3 A;  1P9S A;  2Z3D A;  2AMP A;  4WME A;  2ZU2 A;  3AVZ A;  1Q2W A;  2GTB A;  5B6O A;  5C5N A;  3SNC A;  2Z3C A;  2AMD A;  3TIU A;  1UK2 A;  3E91 A;  1Z1J A;  2GT7 A;  3EA7 A;  2QCY A;  3M3V A;  3SZN A;  4ZUH A;  2D2D A;  3D62 A;  4HI3 A;  4ZRO A;  4XFQ A;  5EU8 A;  2H2Z A;  3ATW A;  3TIT A;  2Q6F A;  5C5O A;  3M3S A; 
#chains in the Genus database with same CATH homology
 2YNB A;  1UJ1 A;  3EBN A;  5HYO A;  3EA8 A;  3TNS A;  2PWX A;  4RSP A;  4MDS A;  3F9G A;  2A5I A;  2V6N A;  2Q6D A;  3VB7 A;  3SNB A;  2K7X A;  4TWW A;  2A5A A;  3VB6 A;  2YNA A;  2A5K A;  2Z94 A;  4TWY A;  3IWM A;  2C3S A;  2Z9L A;  3EA9 A;  4WY3 A;  3M3T A;  3F9E A;  1UK4 A;  3SNA A;  2Z9J A;  1WOF A;  3SND A;  1LVO A;  1Z1I A;  2QIQ A;  2ZU4 A;  3AW1 A;  2ZU5 A;  3TLO A;  3TNT A;  3V3M A;  4WMD A;  3VB3 A;  4WMF A;  2GZ9 A;  1P9U A;  4YOG A;  5GWZ A;  2DUC A;  4YOI A;  2OP9 A;  4YOJ A;  2Z9G A;  2BX4 A;  2GX4 A;  2GZ7 A;  3VB5 A;  3F9F A;  4F49 A;  2LIZ A;  3EAJ A;  4YLU A;  2Q6G A;  3VB4 A;  3SN8 A;  2BX3 A;  3AW0 A;  2Z3E A;  2VJ1 A;  5C3N A;  3SNE A;  2ALV A;  2HOB A;  4YO9 A;  3F9H A;  2GT8 A;  3D23 A;  2GZ8 A;  2QC2 A;  3FZD A;  2AMQ A;  2Z9K A;  1UK3 A;  1P9S A;  2Z3D A;  2AMP A;  4WME A;  2ZU2 A;  3AVZ A;  1Q2W A;  2GTB A;  5B6O A;  5C5N A;  3SNC A;  2Z3C A;  2AMD A;  3TIU A;  1UK2 A;  3E91 A;  1Z1J A;  2GT7 A;  3EA7 A;  2QCY A;  3M3V A;  3SZN A;  4ZUH A;  2D2D A;  3D62 A;  4HI3 A;  4ZRO A;  4XFQ A;  5EU8 A;  2H2Z A;  3ATW A;  3TIT A;  2Q6F A;  5C5O A;  3M3S A; 
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similar chains in the Genus database (?% sequence similarity)
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