3F6UL

Crystal structure of human activated protein c (apc) complexed with ppack
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
98
structure length
98
Chain Sequence
QCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
publication title Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC).
pubmed doi rcsb
molecule keywords Vitamin K-dependent protein C heavy chain
total genus 15
structure length 98
sequence length 98
ec nomenclature ec 3.4.21.69: Protein C (activated).
pdb deposition date 2008-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF00008 EGF EGF-like domain
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3f6uL02
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3f6uL01
2XC0L 2W2QE 4COXA 2Y5HL 4BDWA 3SOBB 4BDXA 3LC3B 3RR3A 1G1SA 4JZFL 4Y76B 2WG4B 3POYA 4MMYB 1JL9A 3FCSB 2VVVL 2UWPB 1IVOC 2GD4A 2Y38A 2BOXA 5I46L 1G1RA 4G1MB 1XKBA 3N8WB 1P0SL 4JZDL 2BOUA 3KQDL 5JBAE 1ATBA 2TGFA 5JVZA 1EQGA 3CS7L 3ENSA 3U7UG 3HPTA 1NFWB 2WPLE 3QCWA 1X7AL 1CCVA 4X8VL 4O02B 1EPGA 1U67A 2XBYL 2W2NE 1PRHA 1L5GB 1I0UA 2FD6A 4XBMA 1MQ6L 2VVUL 4RRZA 3EGFA 3SOQA 2WPME 1EAIC 3KCGL 1J9CL 1ATDA 2NPRA 1YUKB 2VH0B 2WYJB 1CEJA 3KL6B 1ZAQA 1EMOA 3CENL 5IKRA 3BPSE 4ZXXL 4NA9L 1FFMA 3N8WA 3MDLA 3FBYA 2P95L 2BZ6L 1HX2A 3NT1A 3ZYIB 1HREA 1G2LB 2YGPA 4ZAEB 4CUEA 1SZBA 4PH9A 1TPGA 1COUA 1IQML 2WYGB 1B9WA 3IJEB 1IQEL 2W3IB 1HAFA 3NJPC 1IQLL 2XBWL 3N8XA 4Z0LA 3HO5A 1JV2B 4YT6L 1IOEL 3HO4A 1OB1C 3CFWA 3H5CB 3LN1A 2RNLA 5L2YL 1UZKA 3TBDA 5CKMA 1QFKL 4A7IA 4M11A 4BTUA 1NFXB 3GCXE 5IKQA 1P9JA 2WPKE 2UWLB 2PUQL 4Y79B 4ZH8B 2W2PE 2PR3B 1LPZA 4RUTA 1HAEA 2XBXL 2WFTA 4ZXYL 3ELAL 3SW2A 1IJQA 1CQEA 1DX5I 1NPEB 4D0FA 2YGOA 2MHPA 3LIWB 4O1ZA 1IQFL 4M10A 2KL7A 1F7EA 1IQKL 1APQA 1EPHA 4RRWA 5JBBE 1YO8A 3IITB 1G1TA 3TGFA 1MOXC 2MGRA 3GISX 1CX2A 3BT1A 1EPIA 1WHFA 2OYEP 2DDUA 3NTGA 2BOKL 1CVUA 1KSNB 3N8VA 1G1QA 5FDQA 3P5BL 1CVWL 1PTHA 1HT8A 3TH3L 5KIRA 3FFGL 2W3KB 3TZIA 2XC5L 2M74A 5JW1A 4X8SL 3TK6B 2VWMK 3DEMA 1LPKA 2D1JB 1WHEA 2Q1JB 1FE2A 6COXA 2Y5GL 2VH6B 2VJ3A 3PGHA 1M1XB 2VVCK 3TK5B 1F0SB 5COXA 1FAXL 2J2UB 1YGCL 1NFUB 1NZIA 2K2SB 3U73A 1IGXA 2BQ6A 2J95B 2W2OE 4XL1A 1LMJA 2G00L 3KK6A 1KIGL 1YUGA 1HJ7A 4C16A 1IP0A 1XDTR 2BMGA 2W86A 4ISHL 2W2ME 1FF7A 3Q3KB 3F6UL 2FLBL 2B7DL 2J94B 1K37A 1G2MB 1KLJL 3LTFB 1PXXA 4BTTA 2EI8B 5L2ZL 4BXSA 1DIYA 3HS7A 1NQLB 2WPJE 5F1AA 2ADXA 3F1SB 2K2TA 4RRXA 4E1GA 1MQ5L 4D90A 1W7XL 4NGAL 1FJSL 3KQEL 2EI6B 1ATAA 1EBVA 1UZJA 2FLRL 4RS0A 5L30L 3HS6A 2Y80B 4Z0KB 2BOHA 4RRYA 3QH0A 1N7DA 1C5MF 4BTIA 3HS5A 1TOZA 2VWOL 1LQDA 2P16L 3KQCL 4ISIL 2P93L 3K9XA 4LMFA 1FAKL 1L3YA 2F9BL 2AYLA 1IQGL 2JKHL 2XBVL 2Y7ZB 2MGPA 4YZUB 2P26A 5EGMB 4D0EA 3LTGD 3OLTA 3GCWE 3LC5B 4Z6AL 4Y7BB 1ADXA 2Y81B 3V64C 4JZEL 1V3XB 1IQHL 2J34B 2BO2A 2P3TA 2VWNL 1IQIL 5IKVA 2WFXB 3M36L 1GK5A 4BXWA 1HRFA 3V65B 2J38B 2XC4L 3SOVA 1KLOA 1APOA 2RHPA 1ATEA 2P28B 1KLIL 4JYUL 4LORA 5JBCE 1NT0A 1UZPA 4OTJA 1N1IA 5CISA 5JVYA 1EQHA 3C9AC 1PGEA 4FM5A 1F7MA 2RA0L 2KV4A 4TGFA 1NFYB 1RFNB 5CKQA 4CSYA 2EI7B 1DQBA 1FSBA 1WU1B 3CA7A 5CKNA 3N8YA 1TLEA 3LN0A 5JB9E 2J4IB 2CJIB 4OTYA 3ZYJB 2UWOB 3N8ZA 2FLGA 2OYUP 1IOXA 1EGFA 1DDXA 5JB8E 1Z6EL 1HT5A 2Y5FL 1DVAL 4X8TL 1URKA 1XKAL 3MQEA 4CUFA 2FZZL 1O5DL 2W26B 1YUFA 3HO3A 3OLUA 5KN5C 2Y82B 1W8BL 1EZQB 1JBUL 1CCFA 1BF9A 2I9AA 1IQJL 1LPGA 1IGZA 2P3FN 4Y6DB 3ASIA 2WG3C 3M37L 1UZQA 1K36A 5K0HB 2H9EL 1A3PA 2P3UA 4X8UL 3NTBA 4JYVL 3KRKA 1XFEA 3LAQA 4XLWA 3KQBL 1EPJA 4MMXB 2VWLL 1HCGB 1HZ8A 5E8DA 5IKTA 1Z6CA 2KB9A 2WPHE 4ZHAB 4AQTA 2BQWA 2WPIE 2Y7XB 3QMOA 3N8YB 4MMZB 5F19A 4Y71B 2BQ7A 4Y7AB 1Q4GA 4NG9L 1AUTL 1F0RB 1IQNL 2P3FL 2PHBB 4CUDA 2I9BA 3R05A 3ZYGA 1EMNA 4YT7L 3BT2A 3Q7DA 1PFXL 1U8CB 2P94L
chains in the Genus database with same CATH superfamily
2XC0L 2W2QE 4COXA 2Y5HL 4BDWA 3SOBB 4BDXA 3LC3B 3RR3A 1G1SA 4JZFL 4Y76B 2WG4B 3POYA 4MMYB 1JL9A 3FCSB 2VVVL 2UWPB 1IVOC 2GD4A 2Y38A 2BOXA 5I46L 1G1RA 4G1MB 1XKBA 3N8WB 1P0SL 4JZDL 2BOUA 3KQDL 5JBAE 1ATBA 2TGFA 5JVZA 1EQGA 3CS7L 3ENSA 3U7UG 3HPTA 1NFWB 2WPLE 3QCWA 1X7AL 1CCVA 4X8VL 4O02B 1EPGA 1U67A 1V1IA 2XBYL 2W2NE 1PRHA 1L5GB 1I0UA 2FD6A 4XBMA 1MQ6L 2VVUL 4RRZA 3EGFA 3SOQA 4GU3A 2WPME 1EAIC 3KCGL 1J9CL 1ATDA 2NPRA 1YUKB 2VH0B 2WYJB 1CEJA 3KL6B 1ZAQA 1EMOA 3CENL 5IKRA 3BPSE 4ZXXL 4NA9L 1FFMA 3N8WA 3MDLA 3FBYA 2P95L 2BZ6L 1HX2A 3NT1A 3ZYIB 1HREA 1G2LB 2YGPA 4ZAEB 4CUEA 1SZBA 4PH9A 1TPGA 1COUA 1IQML 2WYGB 2HORA 1B9WA 1LMMA 3IJEB 1IQEL 2W3IB 1HAFA 3NJPC 1IQLL 2XBWL 3N8XA 4Z0LA 3HO5A 4GU4A 1JV2B 4YT6L 1IOEL 2JJLA 3HO4A 1OB1C 3CFWA 3H5CB 3LN1A 2RNLA 5L2YL 1UZKA 3TBDA 5CKMA 1QFKL 2BT7A 4M11A 4A7IA 4BTUA 1NFXB 3GCXE 5IKQA 1P9JA 2WPKE 2WZPP 2UWLB 2PUQL 4Y79B 4ZH8B 2W2PE 2PR3B 1LPZA 4RUTA 1HAEA 2XBXL 2WFTA 4ZXYL 3ELAL 3SW2A 1IJQA 1CQEA 1DX5I 1NPEB 4D0FA 2YGOA 2MHPA 3LIWB 4O1ZA 1IQFL 4M10A 2KL7A 1F7EA 1IQKL 1APQA 1EPHA 4RRWA 5JBBE 1YO8A 3IITB 1G1TA 3TGFA 1MOXC 2MGRA 3GISX 1CX2A 3BT1A 1EPIA 1WHFA 2OYEP 2DDUA 3NTGA 2BOKL 1CVUA 1KSNB 3N8VA 1G1QA 5FDQA 3P5BL 1CVWL 1PTHA 1HT8A 3TH3L 5KIRA 3FFGL 2W3KB 3TZIA 2XC5L 2M74A 5JW1A 4X8SL 3TK6B 2VWMK 3DEMA 1LPKA 2D1JB 1WHEA 2Q1JB 1FE2A 6COXA 2Y5GL 2VH6B 2VJ3A 3PGHA 1M1XB 2VVCK 3TK5B 1F0SB 5COXA 1FAXL 2J2UB 1YGCL 1NFUB 1NZIA 2K2SB 3U73A 1IGXA 2BQ6A 2J95B 2W2OE 4XL1A 1LMJA 2G00L 3KK6A 1KIGL 1YUGA 1HJ7A 4C16A 1IP0A 1XDTR 2BMGA 2W86A 4ISHL 2W2ME 1FF7A 3Q3KB 3F6UL 2FLBL 2B7DL 2J94B 1K37A 1G2MB 1KLJL 3LTFB 1PXXA 4BTTA 2EI8B 5L2ZL 4BXSA 1DIYA 3HS7A 1NQLB 2WPJE 5F1AA 2ADXA 3F1SB 2K2TA 4RRXA 4E1GA 1MQ5L 4D90A 1W7XL 4NGAL 1FJSL 3KQEL 2EI6B 4A94C 1ATAA 1EBVA 1UZJA 2FLRL 4RS0A 5L30L 3HS6A 2Y80B 4Z0KB 2BOHA 4RRYA 3QH0A 1N7DA 1C5MF 4BTIA 2HOXA 3HS5A 1TOZA 2VWOL 1LQDA 1LK9A 2H9EC 2P16L 3KQCL 4ISIL 2P93L 3K9XA 4LMFA 1FAKL 1L3YA 2F9BL 2AYLA 1IQGL 2YGQA 2JKHL 2XBVL 2Y7ZB 2MGPA 4YZUB 2P26A 5EGMB 4D0EA 3LTGD 3OLTA 3GCWE 3LC5B 4Z6AL 4Y7BB 1ADXA 2Y81B 3V64C 4JZEL 1V3XB 1IQHL 2J34B 2BO2A 2P3TA 2VWNL 1IQIL 5IKVA 2WFXB 3M36L 1GK5A 4BXWA 1HRFA 3V65B 2J38B 2XC4L 3SOVA 1KLOA 1APOA 2RHPA 1ATEA 2P28B 1KLIL 4JYUL 4LORA 5JBCE 1NT0A 1UZPA 4OTJA 1N1IA 5CISA 5JVYA 1EQHA 3C9AC 1PGEA 4FM5A 1F7MA 2RA0L 2KV4A 4TGFA 1NFYB 1RFNB 5CKQA 4CSYA 2EI7B 1DQBA 1FSBA 1WU1B 3CA7A 5CKNA 3N8YA 1TLEA 3LN0A 5JB9E 2J4IB 2CJIB 4OTYA 3ZYJB 2UWOB 3N8ZA 2FLGA 2KNIA 2OYUP 1IOXA 1EGFA 1DDXA 5JB8E 1Z6EL 1HT5A 2Y5FL 1DVAL 4X8TL 1URKA 1XKAL 3MQEA 4CUFA 2FZZL 1O5DL 2W26B 1YUFA 3HO3A 3OLUA 5KN5C 2Y82B 1W8BL 1EZQB 1JBUL 1CCFA 1BF9A 2I9AA 1IQJL 1LPGA 1IGZA 2P3FN 4Y6DB 3ASIA 2WG3C 3M37L 2BT8A 1UZQA 1K36A 5K0HB 2H9EL 3S6XA 1KKEA 1A3PA 2P3UA 4X8UL 3NTBA 4JYVL 3KRKA 1XFEA 3LAQA 2BSFA 4XLWA 3KQBL 1EPJA 4MMXB 2VWLL 1HCGB 1HZ8A 5E8DA 5IKTA 1Z6CA 2KB9A 2WPHE 4ZHAB 4AQTA 2BQWA 2WPIE 2Y7XB 3QMOA 3N8YB 1V1HA 4MMZB 5F19A 2VRSA 4Y71B 2BQ7A 4Y7AB 1Q4GA 1QIUA 4NG9L 1AUTL 1F0RB 1IQNL 2P3FL 2PHBB 4CUDA 2I9BA 3R05A 3ZYGA 1EMNA 4YT7L 3BT2A 3Q7DA 1PFXL 1U8CB 2P94L
chains in the Genus database with same CATH topology
2XC0L 2W2QE 4COXA 2Y5HL 4BDWA 3SOBB 4BDXA 3LC3B 3RR3A 1G1SA 4JZFL 4Y76B 2WG4B 3POYA 4MMYB 1JL9A 3FCSB 2VVVL 2UWPB 1IVOC 2GD4A 2Y38A 2BOXA 5I46L 1G1RA 4G1MB 1XKBA 3N8WB 1P0SL 4JZDL 2BOUA 3KQDL 5JBAE 1ATBA 2TGFA 5JVZA 1EQGA 3CS7L 3ENSA 3U7UG 3HPTA 1NFWB 2WPLE 3QCWA 1X7AL 1CCVA 4X8VL 4O02B 1EPGA 1U67A 2XBYL 2W2NE 1PRHA 1L5GB 1I0UA 2FD6A 4XBMA 1MQ6L 2VVUL 4RRZA 3EGFA 3SOQA 2WPME 1EAIC 3KCGL 1J9CL 1ATDA 2NPRA 1YUKB 2VH0B 2WYJB 1CEJA 3KL6B 1ZAQA 1EMOA 3CENL 5IKRA 3BPSE 4ZXXL 4NA9L 1FFMA 3N8WA 3MDLA 3FBYA 2P95L 2BZ6L 1HX2A 3NT1A 3ZYIB 1HREA 1G2LB 2YGPA 4ZAEB 4CUEA 1SZBA 4PH9A 1TPGA 1COUA 1IQML 2WYGB 1B9WA 1LMMA 3IJEB 1IQEL 2W3IB 1HAFA 3NJPC 1IQLL 2XBWL 3N8XA 4Z0LA 3HO5A 1JV2B 4YT6L 1IOEL 3HO4A 1OB1C 3CFWA 3H5CB 3LN1A 2RNLA 5L2YL 1UZKA 3TBDA 5CKMA 1QFKL 4A7IA 4M11A 4BTUA 1NFXB 3GCXE 5IKQA 1P9JA 2WPKE 2WZPP 2UWLB 2PUQL 4Y79B 4ZH8B 2W2PE 2PR3B 1LPZA 4RUTA 1HAEA 2XBXL 2WFTA 4ZXYL 3ELAL 3SW2A 1IJQA 1CQEA 1DX5I 1NPEB 4D0FA 2YGOA 2MHPA 3LIWB 4O1ZA 1IQFL 4M10A 2KL7A 1F7EA 1IQKL 1APQA 1EPHA 4RRWA 5JBBE 1YO8A 3IITB 1G1TA 3TGFA 1MOXC 2MGRA 3GISX 1CX2A 3BT1A 1EPIA 1WHFA 2OYEP 2DDUA 3NTGA 2BOKL 1CVUA 1KSNB 3N8VA 1G1QA 5FDQA 3P5BL 1CVWL 1PTHA 1HT8A 3TH3L 5KIRA 3FFGL 2W3KB 3TZIA 2XC5L 2M74A 5JW1A 4X8SL 3TK6B 2VWMK 3DEMA 1LPKA 2D1JB 1WHEA 2Q1JB 1FE2A 6COXA 2Y5GL 2VH6B 2VJ3A 3PGHA 1M1XB 2VVCK 3TK5B 1F0SB 5COXA 1FAXL 2J2UB 1YGCL 1NFUB 1NZIA 2K2SB 3U73A 1IGXA 2BQ6A 2J95B 2W2OE 4XL1A 1LMJA 2G00L 3KK6A 1KIGL 1YUGA 1HJ7A 4C16A 1IP0A 1XDTR 2BMGA 2W86A 4ISHL 2W2ME 1FF7A 3Q3KB 3F6UL 2FLBL 2B7DL 2J94B 1K37A 1G2MB 1KLJL 3LTFB 1PXXA 4BTTA 2EI8B 5L2ZL 4BXSA 1DIYA 3HS7A 1NQLB 2WPJE 5F1AA 2ADXA 3F1SB 2K2TA 4RRXA 4E1GA 1MQ5L 4D90A 1W7XL 4NGAL 1FJSL 3KQEL 2EI6B 4A94C 1ATAA 1EBVA 1UZJA 2FLRL 4RS0A 5L30L 3HS6A 2Y80B 4Z0KB 2BOHA 4RRYA 3QH0A 1N7DA 1C5MF 4BTIA 3HS5A 1TOZA 2VWOL 1LQDA 2H9EC 2P16L 3KQCL 4ISIL 2P93L 3K9XA 4LMFA 1FAKL 1L3YA 2F9BL 2AYLA 1IQGL 2YGQA 2JKHL 2XBVL 2Y7ZB 2MGPA 4YZUB 2P26A 5EGMB 4D0EA 3LTGD 3OLTA 3GCWE 3LC5B 4Z6AL 4Y7BB 1ADXA 2Y81B 3V64C 4JZEL 1V3XB 1IQHL 2J34B 2BO2A 2P3TA 2VWNL 1IQIL 5IKVA 2WFXB 3M36L 1GK5A 4BXWA 1HRFA 3V65B 2J38B 2XC4L 3SOVA 1KLOA 1APOA 2RHPA 1ATEA 2P28B 1KLIL 4JYUL 4LORA 5JBCE 1NT0A 1UZPA 4OTJA 1N1IA 5CISA 5JVYA 1EQHA 3C9AC 1PGEA 4FM5A 1F7MA 2RA0L 2KV4A 4TGFA 1NFYB 1RFNB 5CKQA 4CSYA 2EI7B 1DQBA 1FSBA 1WU1B 3CA7A 5CKNA 3N8YA 1TLEA 3LN0A 5JB9E 2J4IB 2CJIB 4OTYA 3ZYJB 2UWOB 3N8ZA 2FLGA 2KNIA 2OYUP 1IOXA 1EGFA 1DDXA 5JB8E 1Z6EL 1HT5A 2Y5FL 1DVAL 4X8TL 1URKA 1XKAL 3MQEA 4CUFA 2FZZL 1O5DL 2W26B 1YUFA 3HO3A 3OLUA 5KN5C 2Y82B 1W8BL 1EZQB 1JBUL 1CCFA 1BF9A 2I9AA 1IQJL 1LPGA 1IGZA 2P3FN 4Y6DB 3ASIA 2WG3C 3M37L 1UZQA 1K36A 5K0HB 2H9EL 3S6XA 1A3PA 2P3UA 4X8UL 3NTBA 4JYVL 3KRKA 1XFEA 3LAQA 4XLWA 3KQBL 1EPJA 4MMXB 2VWLL 1HCGB 1HZ8A 5E8DA 5IKTA 1Z6CA 2KB9A 2WPHE 4ZHAB 4AQTA 2BQWA 2WPIE 2Y7XB 3QMOA 3N8YB 4MMZB 5F19A 4Y71B 2BQ7A 4Y7AB 1Q4GA 4NG9L 1AUTL 1F0RB 1IQNL 2P3FL 2PHBB 4CUDA 2I9BA 3R05A 3ZYGA 1EMNA 4YT7L 3BT2A 3Q7DA 1PFXL 1U8CB 2P94L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XC0 L;  2W2Q E;  4COX A;  2Y5H L;  4BDW A;  3SOB B;  4BDX A;  3LC3 B;  3RR3 A;  1G1S A;  4JZF L;  4Y76 B;  2WG4 B;  3POY A;  4MMY B;  1JL9 A;  3FCS B;  2VVV L;  2UWP B;  1IVO C;  2GD4 A;  2Y38 A;  2BOX A;  5I46 L;  1G1R A;  4G1M B;  1XKB A;  3N8W B;  1P0S L;  4JZD L;  2BOU A;  3KQD L;  5JBA E;  1ATB A;  2TGF A;  5JVZ A;  1EQG A;  3CS7 L;  3ENS A;  3U7U G;  3HPT A;  1NFW B;  2WPL E;  3QCW A;  1X7A L;  1CCV A;  4X8V L;  4O02 B;  1EPG A;  1U67 A;  2XBY L;  2W2N E;  1PRH A;  1L5G B;  1I0U A;  2FD6 A;  4XBM A;  1MQ6 L;  2VVU L;  4RRZ A;  3EGF A;  3SOQ A;  2WPM E;  1EAI C;  3KCG L;  1J9C L;  1ATD A;  2NPR A;  1YUK B;  2VH0 B;  2WYJ B;  1CEJ A;  3KL6 B;  1ZAQ A;  1EMO A;  3CEN L;  5IKR A;  3BPS E;  4ZXX L;  4NA9 L;  1FFM A;  3N8W A;  3MDL A;  3FBY A;  2P95 L;  2BZ6 L;  1HX2 A;  3NT1 A;  3ZYI B;  1HRE A;  1G2L B;  2YGP A;  4ZAE B;  4CUE A;  1SZB A;  4PH9 A;  1TPG A;  1COU A;  1IQM L;  2WYG B;  1B9W A;  3IJE B;  1IQE L;  2W3I B;  1HAF A;  3NJP C;  1IQL L;  2XBW L;  3N8X A;  4Z0L A;  3HO5 A;  1JV2 B;  4YT6 L;  1IOE L;  3HO4 A;  1OB1 C;  3CFW A;  3H5C B;  3LN1 A;  2RNL A;  5L2Y L;  1UZK A;  3TBD A;  5CKM A;  1QFK L;  4A7I A;  4M11 A;  4BTU A;  1NFX B;  3GCX E;  5IKQ A;  1P9J A;  2WPK E;  2UWL B;  2PUQ L;  4Y79 B;  4ZH8 B;  2W2P E;  2PR3 B;  1LPZ A;  4RUT A;  1HAE A;  2XBX L;  2WFT A;  4ZXY L;  3ELA L;  3SW2 A;  1IJQ A;  1CQE A;  1DX5 I;  1NPE B;  4D0F A;  2YGO A;  2MHP A;  3LIW B;  4O1Z A;  1IQF L;  4M10 A;  2KL7 A;  1F7E A;  1IQK L;  1APQ A;  1EPH A;  4RRW A;  5JBB E;  1YO8 A;  3IIT B;  1G1T A;  3TGF A;  1MOX C;  2MGR A;  3GIS X;  1CX2 A;  3BT1 A;  1EPI A;  1WHF A;  2OYE P;  2DDU A;  3NTG A;  2BOK L;  1CVU A;  1KSN B;  3N8V A;  1G1Q A;  5FDQ A;  3P5B L;  1CVW L;  1PTH A;  1HT8 A;  3TH3 L;  5KIR A;  3FFG L;  2W3K B;  3TZI A;  2XC5 L;  2M74 A;  5JW1 A;  4X8S L;  3TK6 B;  2VWM K;  3DEM A;  1LPK A;  2D1J B;  1WHE A;  2Q1J B;  1FE2 A;  6COX A;  2Y5G L;  2VH6 B;  2VJ3 A;  3PGH A;  1M1X B;  2VVC K;  3TK5 B;  1F0S B;  5COX A;  1FAX L;  2J2U B;  1YGC L;  1NFU B;  1NZI A;  2K2S B;  3U73 A;  1IGX A;  2BQ6 A;  2J95 B;  2W2O E;  4XL1 A;  1LMJ A;  2G00 L;  3KK6 A;  1KIG L;  1YUG A;  1HJ7 A;  4C16 A;  1IP0 A;  1XDT R;  2BMG A;  2W86 A;  4ISH L;  2W2M E;  1FF7 A;  3Q3K B;  3F6U L;  2FLB L;  2B7D L;  2J94 B;  1K37 A;  1G2M B;  1KLJ L;  3LTF B;  1PXX A;  4BTT A;  2EI8 B;  5L2Z L;  4BXS A;  1DIY A;  3HS7 A;  1NQL B;  2WPJ E;  5F1A A;  2ADX A;  3F1S B;  2K2T A;  4RRX A;  4E1G A;  1MQ5 L;  4D90 A;  1W7X L;  4NGA L;  1FJS L;  3KQE L;  2EI6 B;  1ATA A;  1EBV A;  1UZJ A;  2FLR L;  4RS0 A;  5L30 L;  3HS6 A;  2Y80 B;  4Z0K B;  2BOH A;  4RRY A;  3QH0 A;  1N7D A;  1C5M F;  4BTI A;  3HS5 A;  1TOZ A;  2VWO L;  1LQD A;  2P16 L;  3KQC L;  4ISI L;  2P93 L;  3K9X A;  4LMF A;  1FAK L;  1L3Y A;  2F9B L;  2AYL A;  1IQG L;  2JKH L;  2XBV L;  2Y7Z B;  2MGP A;  4YZU B;  2P26 A;  5EGM B;  4D0E A;  3LTG D;  3OLT A;  3GCW E;  3LC5 B;  4Z6A L;  4Y7B B;  1ADX A;  2Y81 B;  3V64 C;  4JZE L;  1V3X B;  1IQH L;  2J34 B;  2BO2 A;  2P3T A;  2VWN L;  1IQI L;  5IKV A;  2WFX B;  3M36 L;  1GK5 A;  4BXW A;  1HRF A;  3V65 B;  2J38 B;  2XC4 L;  3SOV A;  1KLO A;  1APO A;  2RHP A;  1ATE A;  2P28 B;  1KLI L;  4JYU L;  4LOR A;  5JBC E;  1NT0 A;  1UZP A;  4OTJ A;  1N1I A;  5CIS A;  5JVY A;  1EQH A;  3C9A C;  1PGE A;  4FM5 A;  1F7M A;  2RA0 L;  2KV4 A;  4TGF A;  1NFY B;  1RFN B;  5CKQ A;  4CSY A;  2EI7 B;  1DQB A;  1FSB A;  1WU1 B;  3CA7 A;  5CKN A;  3N8Y A;  1TLE A;  3LN0 A;  5JB9 E;  2J4I B;  2CJI B;  4OTY A;  3ZYJ B;  2UWO B;  3N8Z A;  2FLG A;  2OYU P;  1IOX A;  1EGF A;  1DDX A;  5JB8 E;  1Z6E L;  1HT5 A;  2Y5F L;  1DVA L;  4X8T L;  1URK A;  1XKA L;  3MQE A;  4CUF A;  2FZZ L;  1O5D L;  2W26 B;  1YUF A;  3HO3 A;  3OLU A;  5KN5 C;  2Y82 B;  1W8B L;  1EZQ B;  1JBU L;  1CCF A;  1BF9 A;  2I9A A;  1IQJ L;  1LPG A;  1IGZ A;  2P3F N;  4Y6D B;  3ASI A;  2WG3 C;  3M37 L;  1UZQ A;  1K36 A;  5K0H B;  2H9E L;  1A3P A;  2P3U A;  4X8U L;  3NTB A;  4JYV L;  3KRK A;  1XFE A;  3LAQ A;  4XLW A;  3KQB L;  1EPJ A;  4MMX B;  2VWL L;  1HCG B;  1HZ8 A;  5E8D A;  5IKT A;  1Z6C A;  2KB9 A;  2WPH E;  4ZHA B;  4AQT A;  2BQW A;  2WPI E;  2Y7X B;  3QMO A;  3N8Y B;  4MMZ B;  5F19 A;  4Y71 B;  2BQ7 A;  4Y7A B;  1Q4G A;  4NG9 L;  1AUT L;  1F0R B;  1IQN L;  2P3F L;  2PHB B;  4CUD A;  2I9B A;  3R05 A;  3ZYG A;  1EMN A;  4YT7 L;  3BT2 A;  3Q7D A;  1PFX L;  1U8C B;  2P94 L; 
#chains in the Genus database with same CATH topology
 2XC0 L;  2W2Q E;  4COX A;  2Y5H L;  4BDW A;  3SOB B;  4BDX A;  3LC3 B;  3RR3 A;  1G1S A;  4JZF L;  4Y76 B;  2WG4 B;  3POY A;  4MMY B;  1JL9 A;  3FCS B;  2VVV L;  2UWP B;  1IVO C;  2GD4 A;  2Y38 A;  2BOX A;  5I46 L;  1G1R A;  4G1M B;  1XKB A;  3N8W B;  1P0S L;  4JZD L;  2BOU A;  3KQD L;  5JBA E;  1ATB A;  2TGF A;  5JVZ A;  1EQG A;  3CS7 L;  3ENS A;  3U7U G;  3HPT A;  1NFW B;  2WPL E;  3QCW A;  1X7A L;  1CCV A;  4X8V L;  4O02 B;  1EPG A;  1U67 A;  1V1I A;  2XBY L;  2W2N E;  1PRH A;  1L5G B;  1I0U A;  2FD6 A;  4XBM A;  1MQ6 L;  2VVU L;  4RRZ A;  3EGF A;  3SOQ A;  4GU3 A;  2WPM E;  1EAI C;  3KCG L;  1J9C L;  1ATD A;  2NPR A;  1YUK B;  2VH0 B;  2WYJ B;  1CEJ A;  3KL6 B;  1ZAQ A;  1EMO A;  3CEN L;  5IKR A;  3BPS E;  4ZXX L;  4NA9 L;  1FFM A;  3N8W A;  3MDL A;  3FBY A;  2P95 L;  2BZ6 L;  1HX2 A;  3NT1 A;  3ZYI B;  1HRE A;  1G2L B;  2YGP A;  4ZAE B;  4CUE A;  1SZB A;  4PH9 A;  1TPG A;  1COU A;  1IQM L;  2WYG B;  2HOR A;  1B9W A;  1LMM A;  3IJE B;  1IQE L;  2W3I B;  1HAF A;  3NJP C;  1IQL L;  2XBW L;  3N8X A;  4Z0L A;  3HO5 A;  4GU4 A;  1JV2 B;  4YT6 L;  1IOE L;  2JJL A;  3HO4 A;  1OB1 C;  3CFW A;  3H5C B;  3LN1 A;  2RNL A;  5L2Y L;  1UZK A;  3TBD A;  5CKM A;  1QFK L;  2BT7 A;  4M11 A;  4A7I A;  4BTU A;  1NFX B;  3GCX E;  5IKQ A;  1P9J A;  2WPK E;  2WZP P;  2UWL B;  2PUQ L;  4Y79 B;  4ZH8 B;  2W2P E;  2PR3 B;  1LPZ A;  4RUT A;  1HAE A;  2XBX L;  2WFT A;  4ZXY L;  3ELA L;  3SW2 A;  1IJQ A;  1CQE A;  1DX5 I;  1NPE B;  4D0F A;  2YGO A;  2MHP A;  3LIW B;  4O1Z A;  1IQF L;  4M10 A;  2KL7 A;  1F7E A;  1IQK L;  1APQ A;  1EPH A;  4RRW A;  5JBB E;  1YO8 A;  3IIT B;  1G1T A;  3TGF A;  1MOX C;  2MGR A;  3GIS X;  1CX2 A;  3BT1 A;  1EPI A;  1WHF A;  2OYE P;  2DDU A;  3NTG A;  2BOK L;  1CVU A;  1KSN B;  3N8V A;  1G1Q A;  5FDQ A;  3P5B L;  1CVW L;  1PTH A;  1HT8 A;  3TH3 L;  5KIR A;  3FFG L;  2W3K B;  3TZI A;  2XC5 L;  2M74 A;  5JW1 A;  4X8S L;  3TK6 B;  2VWM K;  3DEM A;  1LPK A;  2D1J B;  1WHE A;  2Q1J B;  1FE2 A;  6COX A;  2Y5G L;  2VH6 B;  2VJ3 A;  3PGH A;  1M1X B;  2VVC K;  3TK5 B;  1F0S B;  5COX A;  1FAX L;  2J2U B;  1YGC L;  1NFU B;  1NZI A;  2K2S B;  3U73 A;  1IGX A;  2BQ6 A;  2J95 B;  2W2O E;  4XL1 A;  1LMJ A;  2G00 L;  3KK6 A;  1KIG L;  1YUG A;  1HJ7 A;  4C16 A;  1IP0 A;  1XDT R;  2BMG A;  2W86 A;  4ISH L;  2W2M E;  1FF7 A;  3Q3K B;  3F6U L;  2FLB L;  2B7D L;  2J94 B;  1K37 A;  1G2M B;  1KLJ L;  3LTF B;  1PXX A;  4BTT A;  2EI8 B;  5L2Z L;  4BXS A;  1DIY A;  3HS7 A;  1NQL B;  2WPJ E;  5F1A A;  2ADX A;  3F1S B;  2K2T A;  4RRX A;  4E1G A;  1MQ5 L;  4D90 A;  1W7X L;  4NGA L;  1FJS L;  3KQE L;  2EI6 B;  4A94 C;  1ATA A;  1EBV A;  1UZJ A;  2FLR L;  4RS0 A;  5L30 L;  3HS6 A;  2Y80 B;  4Z0K B;  2BOH A;  4RRY A;  3QH0 A;  1N7D A;  1C5M F;  4BTI A;  2HOX A;  3HS5 A;  1TOZ A;  2VWO L;  1LQD A;  1LK9 A;  2H9E C;  2P16 L;  3KQC L;  4ISI L;  2P93 L;  3K9X A;  4LMF A;  1FAK L;  1L3Y A;  2F9B L;  2AYL A;  1IQG L;  2YGQ A;  2JKH L;  2XBV L;  2Y7Z B;  2MGP A;  4YZU B;  2P26 A;  5EGM B;  4D0E A;  3LTG D;  3OLT A;  3GCW E;  3LC5 B;  4Z6A L;  4Y7B B;  1ADX A;  2Y81 B;  3V64 C;  4JZE L;  1V3X B;  1IQH L;  2J34 B;  2BO2 A;  2P3T A;  2VWN L;  1IQI L;  5IKV A;  2WFX B;  3M36 L;  1GK5 A;  4BXW A;  1HRF A;  3V65 B;  2J38 B;  2XC4 L;  3SOV A;  1KLO A;  1APO A;  2RHP A;  1ATE A;  2P28 B;  1KLI L;  4JYU L;  4LOR A;  5JBC E;  1NT0 A;  1UZP A;  4OTJ A;  1N1I A;  5CIS A;  5JVY A;  1EQH A;  3C9A C;  1PGE A;  4FM5 A;  1F7M A;  2RA0 L;  2KV4 A;  4TGF A;  1NFY B;  1RFN B;  5CKQ A;  4CSY A;  2EI7 B;  1DQB A;  1FSB A;  1WU1 B;  3CA7 A;  5CKN A;  3N8Y A;  1TLE A;  3LN0 A;  5JB9 E;  2J4I B;  2CJI B;  4OTY A;  3ZYJ B;  2UWO B;  3N8Z A;  2FLG A;  2KNI A;  2OYU P;  1IOX A;  1EGF A;  1DDX A;  5JB8 E;  1Z6E L;  1HT5 A;  2Y5F L;  1DVA L;  4X8T L;  1URK A;  1XKA L;  3MQE A;  4CUF A;  2FZZ L;  1O5D L;  2W26 B;  1YUF A;  3HO3 A;  3OLU A;  5KN5 C;  2Y82 B;  1W8B L;  1EZQ B;  1JBU L;  1CCF A;  1BF9 A;  2I9A A;  1IQJ L;  1LPG A;  1IGZ A;  2P3F N;  4Y6D B;  3ASI A;  2WG3 C;  3M37 L;  2BT8 A;  1UZQ A;  1K36 A;  5K0H B;  2H9E L;  3S6X A;  1KKE A;  1A3P A;  2P3U A;  4X8U L;  3NTB A;  4JYV L;  3KRK A;  1XFE A;  3LAQ A;  2BSF A;  4XLW A;  3KQB L;  1EPJ A;  4MMX B;  2VWL L;  1HCG B;  1HZ8 A;  5E8D A;  5IKT A;  1Z6C A;  2KB9 A;  2WPH E;  4ZHA B;  4AQT A;  2BQW A;  2WPI E;  2Y7X B;  3QMO A;  3N8Y B;  1V1H A;  4MMZ B;  5F19 A;  2VRS A;  4Y71 B;  2BQ7 A;  4Y7A B;  1Q4G A;  1QIU A;  4NG9 L;  1AUT L;  1F0R B;  1IQN L;  2P3F L;  2PHB B;  4CUD A;  2I9B A;  3R05 A;  3ZYG A;  1EMN A;  4YT7 L;  3BT2 A;  3Q7D A;  1PFX L;  1U8C B;  2P94 L; 
#chains in the Genus database with same CATH homology
 2XC0 L;  2W2Q E;  4COX A;  2Y5H L;  4BDW A;  3SOB B;  4BDX A;  3LC3 B;  3RR3 A;  1G1S A;  4JZF L;  4Y76 B;  2WG4 B;  3POY A;  4MMY B;  1JL9 A;  3FCS B;  2VVV L;  2UWP B;  1IVO C;  2GD4 A;  2Y38 A;  2BOX A;  5I46 L;  1G1R A;  4G1M B;  1XKB A;  3N8W B;  1P0S L;  4JZD L;  2BOU A;  3KQD L;  5JBA E;  1ATB A;  2TGF A;  5JVZ A;  1EQG A;  3CS7 L;  3ENS A;  3U7U G;  3HPT A;  1NFW B;  2WPL E;  3QCW A;  1X7A L;  1CCV A;  4X8V L;  4O02 B;  1EPG A;  1U67 A;  2XBY L;  2W2N E;  1PRH A;  1L5G B;  1I0U A;  2FD6 A;  4XBM A;  1MQ6 L;  2VVU L;  4RRZ A;  3EGF A;  3SOQ A;  2WPM E;  1EAI C;  3KCG L;  1J9C L;  1ATD A;  2NPR A;  1YUK B;  2VH0 B;  2WYJ B;  1CEJ A;  3KL6 B;  1ZAQ A;  1EMO A;  3CEN L;  5IKR A;  3BPS E;  4ZXX L;  4NA9 L;  1FFM A;  3N8W A;  3MDL A;  3FBY A;  2P95 L;  2BZ6 L;  1HX2 A;  3NT1 A;  3ZYI B;  1HRE A;  1G2L B;  2YGP A;  4ZAE B;  4CUE A;  1SZB A;  4PH9 A;  1TPG A;  1COU A;  1IQM L;  2WYG B;  1B9W A;  1LMM A;  3IJE B;  1IQE L;  2W3I B;  1HAF A;  3NJP C;  1IQL L;  2XBW L;  3N8X A;  4Z0L A;  3HO5 A;  1JV2 B;  4YT6 L;  1IOE L;  3HO4 A;  1OB1 C;  3CFW A;  3H5C B;  3LN1 A;  2RNL A;  5L2Y L;  1UZK A;  3TBD A;  5CKM A;  1QFK L;  4A7I A;  4M11 A;  4BTU A;  1NFX B;  3GCX E;  5IKQ A;  1P9J A;  2WPK E;  2WZP P;  2UWL B;  2PUQ L;  4Y79 B;  4ZH8 B;  2W2P E;  2PR3 B;  1LPZ A;  4RUT A;  1HAE A;  2XBX L;  2WFT A;  4ZXY L;  3ELA L;  3SW2 A;  1IJQ A;  1CQE A;  1DX5 I;  1NPE B;  4D0F A;  2YGO A;  2MHP A;  3LIW B;  4O1Z A;  1IQF L;  4M10 A;  2KL7 A;  1F7E A;  1IQK L;  1APQ A;  1EPH A;  4RRW A;  5JBB E;  1YO8 A;  3IIT B;  1G1T A;  3TGF A;  1MOX C;  2MGR A;  3GIS X;  1CX2 A;  3BT1 A;  1EPI A;  1WHF A;  2OYE P;  2DDU A;  3NTG A;  2BOK L;  1CVU A;  1KSN B;  3N8V A;  1G1Q A;  5FDQ A;  3P5B L;  1CVW L;  1PTH A;  1HT8 A;  3TH3 L;  5KIR A;  3FFG L;  2W3K B;  3TZI A;  2XC5 L;  2M74 A;  5JW1 A;  4X8S L;  3TK6 B;  2VWM K;  3DEM A;  1LPK A;  2D1J B;  1WHE A;  2Q1J B;  1FE2 A;  6COX A;  2Y5G L;  2VH6 B;  2VJ3 A;  3PGH A;  1M1X B;  2VVC K;  3TK5 B;  1F0S B;  5COX A;  1FAX L;  2J2U B;  1YGC L;  1NFU B;  1NZI A;  2K2S B;  3U73 A;  1IGX A;  2BQ6 A;  2J95 B;  2W2O E;  4XL1 A;  1LMJ A;  2G00 L;  3KK6 A;  1KIG L;  1YUG A;  1HJ7 A;  4C16 A;  1IP0 A;  1XDT R;  2BMG A;  2W86 A;  4ISH L;  2W2M E;  1FF7 A;  3Q3K B;  3F6U L;  2FLB L;  2B7D L;  2J94 B;  1K37 A;  1G2M B;  1KLJ L;  3LTF B;  1PXX A;  4BTT A;  2EI8 B;  5L2Z L;  4BXS A;  1DIY A;  3HS7 A;  1NQL B;  2WPJ E;  5F1A A;  2ADX A;  3F1S B;  2K2T A;  4RRX A;  4E1G A;  1MQ5 L;  4D90 A;  1W7X L;  4NGA L;  1FJS L;  3KQE L;  2EI6 B;  4A94 C;  1ATA A;  1EBV A;  1UZJ A;  2FLR L;  4RS0 A;  5L30 L;  3HS6 A;  2Y80 B;  4Z0K B;  2BOH A;  4RRY A;  3QH0 A;  1N7D A;  1C5M F;  4BTI A;  3HS5 A;  1TOZ A;  2VWO L;  1LQD A;  2H9E C;  2P16 L;  3KQC L;  4ISI L;  2P93 L;  3K9X A;  4LMF A;  1FAK L;  1L3Y A;  2F9B L;  2AYL A;  1IQG L;  2YGQ A;  2JKH L;  2XBV L;  2Y7Z B;  2MGP A;  4YZU B;  2P26 A;  5EGM B;  4D0E A;  3LTG D;  3OLT A;  3GCW E;  3LC5 B;  4Z6A L;  4Y7B B;  1ADX A;  2Y81 B;  3V64 C;  4JZE L;  1V3X B;  1IQH L;  2J34 B;  2BO2 A;  2P3T A;  2VWN L;  1IQI L;  5IKV A;  2WFX B;  3M36 L;  1GK5 A;  4BXW A;  1HRF A;  3V65 B;  2J38 B;  2XC4 L;  3SOV A;  1KLO A;  1APO A;  2RHP A;  1ATE A;  2P28 B;  1KLI L;  4JYU L;  4LOR A;  5JBC E;  1NT0 A;  1UZP A;  4OTJ A;  1N1I A;  5CIS A;  5JVY A;  1EQH A;  3C9A C;  1PGE A;  4FM5 A;  1F7M A;  2RA0 L;  2KV4 A;  4TGF A;  1NFY B;  1RFN B;  5CKQ A;  4CSY A;  2EI7 B;  1DQB A;  1FSB A;  1WU1 B;  3CA7 A;  5CKN A;  3N8Y A;  1TLE A;  3LN0 A;  5JB9 E;  2J4I B;  2CJI B;  4OTY A;  3ZYJ B;  2UWO B;  3N8Z A;  2FLG A;  2KNI A;  2OYU P;  1IOX A;  1EGF A;  1DDX A;  5JB8 E;  1Z6E L;  1HT5 A;  2Y5F L;  1DVA L;  4X8T L;  1URK A;  1XKA L;  3MQE A;  4CUF A;  2FZZ L;  1O5D L;  2W26 B;  1YUF A;  3HO3 A;  3OLU A;  5KN5 C;  2Y82 B;  1W8B L;  1EZQ B;  1JBU L;  1CCF A;  1BF9 A;  2I9A A;  1IQJ L;  1LPG A;  1IGZ A;  2P3F N;  4Y6D B;  3ASI A;  2WG3 C;  3M37 L;  1UZQ A;  1K36 A;  5K0H B;  2H9E L;  3S6X A;  1A3P A;  2P3U A;  4X8U L;  3NTB A;  4JYV L;  3KRK A;  1XFE A;  3LAQ A;  4XLW A;  3KQB L;  1EPJ A;  4MMX B;  2VWL L;  1HCG B;  1HZ8 A;  5E8D A;  5IKT A;  1Z6C A;  2KB9 A;  2WPH E;  4ZHA B;  4AQT A;  2BQW A;  2WPI E;  2Y7X B;  3QMO A;  3N8Y B;  4MMZ B;  5F19 A;  4Y71 B;  2BQ7 A;  4Y7A B;  1Q4G A;  4NG9 L;  1AUT L;  1F0R B;  1IQN L;  2P3F L;  2PHB B;  4CUD A;  2I9B A;  3R05 A;  3ZYG A;  1EMN A;  4YT7 L;  3BT2 A;  3Q7D A;  1PFX L;  1U8C B;  2P94 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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