3GCWE

Pcsk9:egfa(h306y)
Total Genus 6
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
41
structure length
41
Chain Sequence
MGTNECLDNNGGCSYVCNDLKIGYECLCPDGFQLVAQRRCE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Antagonism of Secreted PCSK9 Increases Low Density Lipoprotein Receptor Expression in HepG2 Cells.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Proprotein convertase subtilisin/kexin type 9
total genus 6
structure length 41
sequence length 41
ec nomenclature
pdb deposition date 2009-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF12662 cEGF Complement Clr-like EGF-like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3gcwE00
1G2MB 5CKMA 1C5MF 1CVWL 2Y80B 2W3KB 4D0EA 3CFWA 5CISA 1G1QA 1LPKA 5KN5C 5CKQA 1NFUB 3HO3A 3N8VA 2W2NE 5L2ZL 3TH3L 5K0HB 2XBYL 1F0SB 1PRHA 1IQHL 3MQEA 2J2UB 4OTJA 3OLUA 3N8WB 4ZAEB 2Y38A 1IOXA 2P3FL 1KSNB 2Q1JB 2BQ6A 1HCGB 2UWPB 3HPTA 1URKA 1IP0A 2W2ME 1ATBA 3GCXE 2VVCK 1DDXA 5JVZA 3M37L 1WU1B 1JBUL 4BXSA 4CUEA 3FCSB 4OTYA 1LQDA 4YZUB 2WG3C 2Y82B 3K9XA 1EQHA 3KL6B 3FBYA 5JBCE 2K2TA 1FSBA 1FJSL 5E8DA 1IJQA 2P3UA 4Y6DB 1HAEA 2CJIB 1UZPA 2OYUP 1HX2A 3TK5B 5IKVA 3LC5B 1PGEA 2RHPA 3U73A 3NJPC 2XBXL 6COXA 5KIRA 2P28B 1WHFA 1K36A 2MGRA 2J95B 1Z6EL 2KL7A 1FAKL 4BTUA 2XC4L 2YGOA 1PXXA 5IKTA 1EPHA 3LAQA 2BZ6L 1IQFL 2XC0L 3F6UL 2P95L 4E1GA 2W3IB 2Y81B 4G1MB 4LORA 4RRZA 1EPIA 1F7MA 1O5DL 4MMXB 1YUGA 2WG4B 1CCFA 1NQLB 1ATDA 4NG9L 4BDWA 3IITB 1KIGL 5JBAE 2D1JB 2VWLL 3N8ZA 2P94L 2WPLE 4RRYA 3ZYIB 4ZH8B 1UZQA 4BTIA 3Q3KB 1CQEA 2BO2A 5CKNA 1AUTL 2Y5HL 3RR3A 1XFEA 2W2QE 5FDQA 2W2OE 1BF9A 2M74A 2P3TA 4FM5A 1SZBA 1DIYA 1W7XL 2PUQL 3KQDL 3F1SB 1OB1C 1APOA 1RFNB 2VVVL 1TLEA 1JL9A 3IJEB 1APQA 3KRKA 4JYVL 1NFWB 3QH0A 1W8BL 1G2LB 2P16L 1G1SA 2H9EL 3HS5A 1EZQB 1N7DA 3SOQA 1NT0A 3V65B 5JW1A 1XKBA 2NPRA 1K37A 2W2PE 3SOBB 1FAXL 1NPEB 2MHPA 1NFYB 5JBBE 2VJ3A 1MQ5L 4Z0LA 1YO8A 4JYUL 3LN1A 3LTFB 1HREA 3KK6A 2EI8B 3POYA 2Y7XB 1P9JA 1EBVA 1I0UA 2FD6A 1IGZA 1FE2A 4D90A 4ZHAB 4Y76B 5IKQA 4Z0KB 1YGCL 4ISHL 2P3FN 2P93L 1UZKA 1U67A 3HO4A 2K2SB 1JV2B 2WPJE 4C16A 2GD4A 4NGAL 3N8YA 2AYLA 1HRFA 2J4IB 2I9BA 4XLWA 1IQGL 1IQEL 4YT7L 3MDLA 1F0RB 4AQTA 4BTTA 2VWNL 4JZFL 3ZYGA 1J9CL 4RRWA 4M11A 2PHBB 3SOVA 2XC5L 4M10A 1IQLL 3OLTA 3TBDA 2WPME 5I46L 3GISX 4X8SL 3NT1A 1EPGA 3M36L 2J94B 2JKHL 1MOXC 1IOEL 3C9AC 3BPSE 3KQBL 4NA9L 1XDTR 2J38B 3HS7A 2FLBL 2VVUL 1HZ8A 1DX5I 2VH0B 2WPKE 2OYEP 2DDUA 1F7EA 3EGFA 2WFXB 1LPZA 2KB9A 1YUFA 1TPGA 3BT2A 1FFMA 5F19A 3U7UG 1EQGA 3N8WA 2UWLB 4XL1A 2VH6B 2Y7ZB 1V3XB 2ADXA 4ISIL 1ZAQA 1EMOA 2XBWL 3NTGA 1IVOC 2WPIE 1KLOA 2WYJB 4MMYB 3LC3B 1G1RA 3FFGL 3GCWE 2WYGB 3V64C 1ATEA 1NFXB 3HS6A 1EAIC 2FLRL 1HAFA 1M1XB 1CCVA 3CA7A 2KV4A 1HJ7A 3BT1A 4JZDL 1YUKB 1B9WA 4COXA 4Z6AL 1IQNL 2TGFA 4ZXYL 4BXWA 1G1TA 4CUDA 3PGHA 2BQ7A 1KLJL 5JVYA 2BOKL 1UZJA 2W26B 2J34B 5L30L 3Q7DA 3ENSA 2B7DL 1CVUA 2MGPA 2VWOL 4RUTA 2EI7B 3NTBA 1COUA 5COXA 1FF7A 1DVAL 2RA0L 1IGXA 1NZIA 1Z6CA 3DEMA 2P26A 4X8TL 3N8XA 4ZXXL 2FZZL 2G00L 4A7IA 1CEJA 2BQWA 4Y79B 2YGPA 1DQBA 2I9AA 3ASIA 2BOXA 1MQ6L 2BOHA 3TK6B 3KQCL 2EI6B 3CENL 2WPHE 4O02B 2F9BL 2BMGA 3QCWA 1Q4GA 4MMZB 1EMNA 2WFTA 1TOZA 1IQJL 1IQKL 2BOUA 3LN0A 5JB9E 3KCGL 3SW2A 1PFXL 3R05A 4X8UL 1U8CB 2FLGA 4CSYA 3HO5A 1EGFA 4RRXA 1L3YA 1ADXA 3LIWB 4JZEL 5EGMB 2Y5GL 2VWMK 3QMOA 1GK5A 1N1IA 1HT5A 3P5BL 2UWOB 1IQML 4XBMA 1LPGA 4Y7AB 3TZIA 1QFKL 4CUFA 1A3PA 4PH9A 1IQIL 2PR3B 1KLIL 2RNLA 3H5CB 4Y7BB 2W86A 2XBVL 1L5GB 3TGFA 4YT6L 3LTGD 1LMJA 1ATAA 3KQEL 4RS0A 1CX2A 5L2YL 3CS7L 4Y71B 4TGFA 1HT8A 3N8YB 4O1ZA 1WHEA 4D0FA 1X7AL 1P0SL 4BDXA 1XKAL 5JB8E 5IKRA 3ZYJB 1PTHA 1EPJA 3ELAL 2Y5FL 5F1AA 4X8VL 4LMFA
chains in the Genus database with same CATH superfamily
1G2MB 5CKMA 1C5MF 1CVWL 2Y80B 2W3KB 4D0EA 3CFWA 5CISA 1G1QA 1LPKA 5KN5C 5CKQA 1NFUB 3HO3A 3N8VA 2W2NE 5L2ZL 3TH3L 5K0HB 2XBYL 1F0SB 1PRHA 1IQHL 3MQEA 2J2UB 4OTJA 3OLUA 3N8WB 4ZAEB 2Y38A 1IOXA 2P3FL 1KSNB 1V1HA 2Q1JB 2BQ6A 1HCGB 2UWPB 3HPTA 1URKA 1IP0A 2W2ME 1ATBA 3GCXE 2VVCK 1DDXA 5JVZA 3M37L 1WU1B 1JBUL 4BXSA 4CUEA 3FCSB 4OTYA 1LQDA 4YZUB 2WG3C 2Y82B 3K9XA 4A94C 1EQHA 3KL6B 3FBYA 5JBCE 1LK9A 2K2TA 1FSBA 1FJSL 5E8DA 1IJQA 2P3UA 4Y6DB 1HAEA 2CJIB 1UZPA 2OYUP 1HX2A 1KKEA 3TK5B 5IKVA 3S6XA 2YGQA 3LC5B 1PGEA 2RHPA 3U73A 3NJPC 2XBXL 6COXA 5KIRA 2P28B 1WHFA 1K36A 2MGRA 2J95B 1Z6EL 2KL7A 1FAKL 4BTUA 2XC4L 2YGOA 1PXXA 5IKTA 1EPHA 3LAQA 2BZ6L 1IQFL 2XC0L 3F6UL 2P95L 4E1GA 2W3IB 2Y81B 4G1MB 4LORA 4RRZA 1EPIA 1F7MA 1O5DL 4MMXB 1YUGA 2WG4B 1CCFA 1NQLB 1ATDA 4NG9L 4BDWA 3IITB 1KIGL 5JBAE 2D1JB 2VWLL 3N8ZA 2P94L 2WPLE 4RRYA 3ZYIB 4ZH8B 1UZQA 4BTIA 3Q3KB 1CQEA 2BO2A 5CKNA 1AUTL 2Y5HL 3RR3A 1XFEA 2W2QE 5FDQA 2W2OE 1BF9A 2M74A 2P3TA 4FM5A 1SZBA 1DIYA 1W7XL 2PUQL 3KQDL 3F1SB 1OB1C 1LMMA 1APOA 2VRSA 1RFNB 2VVVL 1TLEA 4GU3A 1JL9A 3IJEB 1APQA 3KRKA 4JYVL 1NFWB 3QH0A 1W8BL 1G2LB 2P16L 1G1SA 2H9EL 1QIUA 3HS5A 1EZQB 1N7DA 3SOQA 1NT0A 3V65B 5JW1A 1XKBA 2NPRA 1K37A 2W2PE 3SOBB 1FAXL 1NPEB 2MHPA 1NFYB 5JBBE 2VJ3A 1MQ5L 4Z0LA 1YO8A 4JYUL 3LN1A 3LTFB 1HREA 3KK6A 2EI8B 3POYA 2Y7XB 1P9JA 2BT8A 1EBVA 1I0UA 2BT7A 2FD6A 1IGZA 1FE2A 4D90A 4ZHAB 4Y76B 5IKQA 4Z0KB 1YGCL 4ISHL 2P3FN 2P93L 1UZKA 1U67A 2BSFA 2K2SB 3HO4A 1JV2B 2WPJE 4C16A 2GD4A 4NGAL 3N8YA 2WZPP 2AYLA 1HRFA 2J4IB 2I9BA 4XLWA 1IQGL 1IQEL 4YT7L 3MDLA 1F0RB 4AQTA 4BTTA 2VWNL 4JZFL 3ZYGA 1J9CL 4RRWA 4M11A 2PHBB 3SOVA 2XC5L 4M10A 1IQLL 3OLTA 3TBDA 2WPME 5I46L 3GISX 4X8SL 3NT1A 1EPGA 3M36L 2J94B 2JKHL 1MOXC 1IOEL 3C9AC 3BPSE 3KQBL 4NA9L 1XDTR 2J38B 3HS7A 2FLBL 2VVUL 1HZ8A 1DX5I 2VH0B 2WPKE 2OYEP 2DDUA 1F7EA 3EGFA 2WFXB 1LPZA 2KB9A 1YUFA 1TPGA 3BT2A 1FFMA 5F19A 3U7UG 1EQGA 3N8WA 2UWLB 4XL1A 2VH6B 2Y7ZB 1V3XB 2ADXA 4ISIL 1ZAQA 1EMOA 2XBWL 3NTGA 1IVOC 2WPIE 1KLOA 2WYJB 4MMYB 3LC3B 1G1RA 3FFGL 3GCWE 2WYGB 3V64C 1ATEA 1NFXB 3HS6A 1EAIC 2FLRL 1HAFA 1M1XB 1CCVA 2HOXA 3CA7A 2KV4A 1HJ7A 2JJLA 3BT1A 4JZDL 1YUKB 1B9WA 4COXA 4Z6AL 1IQNL 2TGFA 4ZXYL 4BXWA 1G1TA 4CUDA 3PGHA 2BQ7A 1KLJL 5JVYA 2BOKL 1UZJA 2W26B 2J34B 5L30L 3Q7DA 3ENSA 2B7DL 1CVUA 2MGPA 2VWOL 4RUTA 2EI7B 2HORA 3NTBA 1COUA 5COXA 1FF7A 1DVAL 2RA0L 1IGXA 1NZIA 1Z6CA 3DEMA 2P26A 4X8TL 3N8XA 4ZXXL 2FZZL 2G00L 4A7IA 1CEJA 2BQWA 4Y79B 2YGPA 1DQBA 2I9AA 3ASIA 2BOXA 1MQ6L 2BOHA 3TK6B 3KQCL 2EI6B 3CENL 2WPHE 4GU4A 4O02B 2F9BL 2BMGA 3QCWA 1Q4GA 4MMZB 1EMNA 2WFTA 1TOZA 1IQJL 1IQKL 2BOUA 3LN0A 5JB9E 3KCGL 3SW2A 1PFXL 3R05A 4X8UL 1U8CB 2FLGA 4CSYA 3HO5A 1EGFA 4RRXA 1L3YA 1ADXA 3LIWB 4JZEL 5EGMB 2Y5GL 2VWMK 3QMOA 1GK5A 1N1IA 1HT5A 3P5BL 2UWOB 1IQML 4XBMA 1LPGA 4Y7AB 3TZIA 1QFKL 4CUFA 1A3PA 4PH9A 1IQIL 2PR3B 1KLIL 2RNLA 3H5CB 2H9EC 4Y7BB 2W86A 2XBVL 1L5GB 3TGFA 4YT6L 3LTGD 1LMJA 1ATAA 3KQEL 4RS0A 1CX2A 5L2YL 3CS7L 4Y71B 1V1IA 2KNIA 4TGFA 1HT8A 3N8YB 4O1ZA 1WHEA 4D0FA 1X7AL 1P0SL 4BDXA 1XKAL 5JB8E 5IKRA 3ZYJB 1PTHA 1EPJA 3ELAL 2Y5FL 5F1AA 4X8VL 4LMFA
chains in the Genus database with same CATH topology
1G2MB 5CKMA 1C5MF 1CVWL 2Y80B 2W3KB 4D0EA 3CFWA 5CISA 1G1QA 1LPKA 5KN5C 5CKQA 1NFUB 3HO3A 3N8VA 2W2NE 5L2ZL 3TH3L 5K0HB 2XBYL 1F0SB 1PRHA 1IQHL 3MQEA 2J2UB 4OTJA 3OLUA 3N8WB 4ZAEB 2Y38A 1IOXA 2P3FL 1KSNB 2Q1JB 2BQ6A 1HCGB 2UWPB 3HPTA 1URKA 1IP0A 2W2ME 1ATBA 3GCXE 2VVCK 1DDXA 5JVZA 3M37L 1WU1B 1JBUL 4BXSA 4CUEA 3FCSB 4OTYA 1LQDA 4YZUB 2WG3C 2Y82B 3K9XA 4A94C 1EQHA 3KL6B 3FBYA 5JBCE 2K2TA 1FSBA 1FJSL 5E8DA 1IJQA 2P3UA 4Y6DB 1HAEA 2CJIB 1UZPA 2OYUP 1HX2A 3TK5B 5IKVA 3S6XA 2YGQA 3LC5B 1PGEA 2RHPA 3U73A 3NJPC 2XBXL 6COXA 5KIRA 2P28B 1WHFA 1K36A 2MGRA 2J95B 1Z6EL 2KL7A 1FAKL 4BTUA 2XC4L 2YGOA 1PXXA 5IKTA 1EPHA 3LAQA 2BZ6L 1IQFL 2XC0L 3F6UL 2P95L 4E1GA 2W3IB 2Y81B 4G1MB 4LORA 4RRZA 1EPIA 1F7MA 1O5DL 4MMXB 1YUGA 2WG4B 1CCFA 1NQLB 1ATDA 4NG9L 4BDWA 3IITB 1KIGL 5JBAE 2D1JB 2VWLL 3N8ZA 2P94L 2WPLE 4RRYA 3ZYIB 4ZH8B 1UZQA 4BTIA 3Q3KB 1CQEA 2BO2A 5CKNA 1AUTL 2Y5HL 3RR3A 1XFEA 2W2QE 5FDQA 2W2OE 1BF9A 2M74A 2P3TA 4FM5A 1SZBA 1DIYA 1W7XL 2PUQL 3KQDL 3F1SB 1OB1C 1LMMA 1APOA 1RFNB 2VVVL 1TLEA 1JL9A 3IJEB 1APQA 3KRKA 4JYVL 1NFWB 3QH0A 1W8BL 1G2LB 2P16L 1G1SA 2H9EL 3HS5A 1EZQB 1N7DA 3SOQA 1NT0A 3V65B 5JW1A 1XKBA 2NPRA 1K37A 2W2PE 3SOBB 1FAXL 1NPEB 2MHPA 1NFYB 5JBBE 2VJ3A 1MQ5L 4Z0LA 1YO8A 4JYUL 3LN1A 3LTFB 1HREA 3KK6A 2EI8B 3POYA 2Y7XB 1P9JA 1EBVA 1I0UA 2FD6A 1IGZA 1FE2A 4D90A 4ZHAB 4Y76B 5IKQA 4Z0KB 1YGCL 4ISHL 2P3FN 2P93L 1UZKA 1U67A 3HO4A 2K2SB 1JV2B 2WPJE 4C16A 2GD4A 4NGAL 3N8YA 2WZPP 2AYLA 1HRFA 2J4IB 2I9BA 4XLWA 1IQGL 1IQEL 4YT7L 3MDLA 1F0RB 4AQTA 4BTTA 2VWNL 4JZFL 3ZYGA 1J9CL 4RRWA 4M11A 2PHBB 3SOVA 2XC5L 4M10A 1IQLL 3OLTA 3TBDA 2WPME 5I46L 3GISX 4X8SL 3NT1A 1EPGA 3M36L 2J94B 2JKHL 1MOXC 1IOEL 3C9AC 3BPSE 3KQBL 4NA9L 1XDTR 2J38B 3HS7A 2FLBL 2VVUL 1HZ8A 1DX5I 2VH0B 2WPKE 2OYEP 2DDUA 1F7EA 3EGFA 2WFXB 1LPZA 2KB9A 1YUFA 1TPGA 3BT2A 1FFMA 5F19A 3U7UG 1EQGA 3N8WA 2UWLB 4XL1A 2VH6B 2Y7ZB 1V3XB 2ADXA 4ISIL 1ZAQA 1EMOA 2XBWL 3NTGA 1IVOC 2WPIE 1KLOA 2WYJB 4MMYB 3LC3B 1G1RA 3FFGL 3GCWE 2WYGB 3V64C 1ATEA 1NFXB 3HS6A 1EAIC 2FLRL 1HAFA 1M1XB 1CCVA 3CA7A 2KV4A 1HJ7A 3BT1A 4JZDL 1YUKB 1B9WA 4COXA 4Z6AL 1IQNL 2TGFA 4ZXYL 4BXWA 1G1TA 4CUDA 3PGHA 2BQ7A 1KLJL 5JVYA 2BOKL 1UZJA 2W26B 2J34B 5L30L 3Q7DA 3ENSA 2B7DL 1CVUA 2MGPA 2VWOL 4RUTA 2EI7B 3NTBA 1COUA 5COXA 1FF7A 1DVAL 2RA0L 1IGXA 1NZIA 1Z6CA 3DEMA 2P26A 4X8TL 3N8XA 4ZXXL 2FZZL 2G00L 4A7IA 1CEJA 2BQWA 4Y79B 2YGPA 1DQBA 2I9AA 3ASIA 2BOXA 1MQ6L 2BOHA 3TK6B 3KQCL 2EI6B 3CENL 2WPHE 4O02B 2F9BL 2BMGA 3QCWA 1Q4GA 4MMZB 1EMNA 2WFTA 1TOZA 1IQJL 1IQKL 2BOUA 3LN0A 5JB9E 3KCGL 3SW2A 1PFXL 3R05A 4X8UL 1U8CB 2FLGA 4CSYA 3HO5A 1EGFA 4RRXA 1L3YA 1ADXA 3LIWB 4JZEL 5EGMB 2Y5GL 2VWMK 3QMOA 1GK5A 1N1IA 1HT5A 3P5BL 2UWOB 1IQML 4XBMA 1LPGA 4Y7AB 3TZIA 1QFKL 4CUFA 1A3PA 4PH9A 1IQIL 2PR3B 1KLIL 2RNLA 3H5CB 2H9EC 4Y7BB 2W86A 2XBVL 1L5GB 3TGFA 4YT6L 3LTGD 1LMJA 1ATAA 3KQEL 4RS0A 1CX2A 5L2YL 3CS7L 4Y71B 2KNIA 4TGFA 1HT8A 3N8YB 4O1ZA 1WHEA 4D0FA 1X7AL 1P0SL 4BDXA 1XKAL 5JB8E 5IKRA 3ZYJB 1PTHA 1EPJA 3ELAL 2Y5FL 5F1AA 4X8VL 4LMFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1G2M B;  5CKM A;  1C5M F;  1CVW L;  2Y80 B;  2W3K B;  4D0E A;  3CFW A;  5CIS A;  1G1Q A;  1LPK A;  5KN5 C;  5CKQ A;  1NFU B;  3HO3 A;  3N8V A;  2W2N E;  5L2Z L;  3TH3 L;  5K0H B;  2XBY L;  1F0S B;  1PRH A;  1IQH L;  3MQE A;  2J2U B;  4OTJ A;  3OLU A;  3N8W B;  4ZAE B;  2Y38 A;  1IOX A;  2P3F L;  1KSN B;  2Q1J B;  2BQ6 A;  1HCG B;  2UWP B;  3HPT A;  1URK A;  1IP0 A;  2W2M E;  1ATB A;  3GCX E;  2VVC K;  1DDX A;  5JVZ A;  3M37 L;  1WU1 B;  1JBU L;  4BXS A;  4CUE A;  3FCS B;  4OTY A;  1LQD A;  4YZU B;  2WG3 C;  2Y82 B;  3K9X A;  1EQH A;  3KL6 B;  3FBY A;  5JBC E;  2K2T A;  1FSB A;  1FJS L;  5E8D A;  1IJQ A;  2P3U A;  4Y6D B;  1HAE A;  2CJI B;  1UZP A;  2OYU P;  1HX2 A;  3TK5 B;  5IKV A;  3LC5 B;  1PGE A;  2RHP A;  3U73 A;  3NJP C;  2XBX L;  6COX A;  5KIR A;  2P28 B;  1WHF A;  1K36 A;  2MGR A;  2J95 B;  1Z6E L;  2KL7 A;  1FAK L;  4BTU A;  2XC4 L;  2YGO A;  1PXX A;  5IKT A;  1EPH A;  3LAQ A;  2BZ6 L;  1IQF L;  2XC0 L;  3F6U L;  2P95 L;  4E1G A;  2W3I B;  2Y81 B;  4G1M B;  4LOR A;  4RRZ A;  1EPI A;  1F7M A;  1O5D L;  4MMX B;  1YUG A;  2WG4 B;  1CCF A;  1NQL B;  1ATD A;  4NG9 L;  4BDW A;  3IIT B;  1KIG L;  5JBA E;  2D1J B;  2VWL L;  3N8Z A;  2P94 L;  2WPL E;  4RRY A;  3ZYI B;  4ZH8 B;  1UZQ A;  4BTI A;  3Q3K B;  1CQE A;  2BO2 A;  5CKN A;  1AUT L;  2Y5H L;  3RR3 A;  1XFE A;  2W2Q E;  5FDQ A;  2W2O E;  1BF9 A;  2M74 A;  2P3T A;  4FM5 A;  1SZB A;  1DIY A;  1W7X L;  2PUQ L;  3KQD L;  3F1S B;  1OB1 C;  1APO A;  1RFN B;  2VVV L;  1TLE A;  1JL9 A;  3IJE B;  1APQ A;  3KRK A;  4JYV L;  1NFW B;  3QH0 A;  1W8B L;  1G2L B;  2P16 L;  1G1S A;  2H9E L;  3HS5 A;  1EZQ B;  1N7D A;  3SOQ A;  1NT0 A;  3V65 B;  5JW1 A;  1XKB A;  2NPR A;  1K37 A;  2W2P E;  3SOB B;  1FAX L;  1NPE B;  2MHP A;  1NFY B;  5JBB E;  2VJ3 A;  1MQ5 L;  4Z0L A;  1YO8 A;  4JYU L;  3LN1 A;  3LTF B;  1HRE A;  3KK6 A;  2EI8 B;  3POY A;  2Y7X B;  1P9J A;  1EBV A;  1I0U A;  2FD6 A;  1IGZ A;  1FE2 A;  4D90 A;  4ZHA B;  4Y76 B;  5IKQ A;  4Z0K B;  1YGC L;  4ISH L;  2P3F N;  2P93 L;  1UZK A;  1U67 A;  3HO4 A;  2K2S B;  1JV2 B;  2WPJ E;  4C16 A;  2GD4 A;  4NGA L;  3N8Y A;  2AYL A;  1HRF A;  2J4I B;  2I9B A;  4XLW A;  1IQG L;  1IQE L;  4YT7 L;  3MDL A;  1F0R B;  4AQT A;  4BTT A;  2VWN L;  4JZF L;  3ZYG A;  1J9C L;  4RRW A;  4M11 A;  2PHB B;  3SOV A;  2XC5 L;  4M10 A;  1IQL L;  3OLT A;  3TBD A;  2WPM E;  5I46 L;  3GIS X;  4X8S L;  3NT1 A;  1EPG A;  3M36 L;  2J94 B;  2JKH L;  1MOX C;  1IOE L;  3C9A C;  3BPS E;  3KQB L;  4NA9 L;  1XDT R;  2J38 B;  3HS7 A;  2FLB L;  2VVU L;  1HZ8 A;  1DX5 I;  2VH0 B;  2WPK E;  2OYE P;  2DDU A;  1F7E A;  3EGF A;  2WFX B;  1LPZ A;  2KB9 A;  1YUF A;  1TPG A;  3BT2 A;  1FFM A;  5F19 A;  3U7U G;  1EQG A;  3N8W A;  2UWL B;  4XL1 A;  2VH6 B;  2Y7Z B;  1V3X B;  2ADX A;  4ISI L;  1ZAQ A;  1EMO A;  2XBW L;  3NTG A;  1IVO C;  2WPI E;  1KLO A;  2WYJ B;  4MMY B;  3LC3 B;  1G1R A;  3FFG L;  3GCW E;  2WYG B;  3V64 C;  1ATE A;  1NFX B;  3HS6 A;  1EAI C;  2FLR L;  1HAF A;  1M1X B;  1CCV A;  3CA7 A;  2KV4 A;  1HJ7 A;  3BT1 A;  4JZD L;  1YUK B;  1B9W A;  4COX A;  4Z6A L;  1IQN L;  2TGF A;  4ZXY L;  4BXW A;  1G1T A;  4CUD A;  3PGH A;  2BQ7 A;  1KLJ L;  5JVY A;  2BOK L;  1UZJ A;  2W26 B;  2J34 B;  5L30 L;  3Q7D A;  3ENS A;  2B7D L;  1CVU A;  2MGP A;  2VWO L;  4RUT A;  2EI7 B;  3NTB A;  1COU A;  5COX A;  1FF7 A;  1DVA L;  2RA0 L;  1IGX A;  1NZI A;  1Z6C A;  3DEM A;  2P26 A;  4X8T L;  3N8X A;  4ZXX L;  2FZZ L;  2G00 L;  4A7I A;  1CEJ A;  2BQW A;  4Y79 B;  2YGP A;  1DQB A;  2I9A A;  3ASI A;  2BOX A;  1MQ6 L;  2BOH A;  3TK6 B;  3KQC L;  2EI6 B;  3CEN L;  2WPH E;  4O02 B;  2F9B L;  2BMG A;  3QCW A;  1Q4G A;  4MMZ B;  1EMN A;  2WFT A;  1TOZ A;  1IQJ L;  1IQK L;  2BOU A;  3LN0 A;  5JB9 E;  3KCG L;  3SW2 A;  1PFX L;  3R05 A;  4X8U L;  1U8C B;  2FLG A;  4CSY A;  3HO5 A;  1EGF A;  4RRX A;  1L3Y A;  1ADX A;  3LIW B;  4JZE L;  5EGM B;  2Y5G L;  2VWM K;  3QMO A;  1GK5 A;  1N1I A;  1HT5 A;  3P5B L;  2UWO B;  1IQM L;  4XBM A;  1LPG A;  4Y7A B;  3TZI A;  1QFK L;  4CUF A;  1A3P A;  4PH9 A;  1IQI L;  2PR3 B;  1KLI L;  2RNL A;  3H5C B;  4Y7B B;  2W86 A;  2XBV L;  1L5G B;  3TGF A;  4YT6 L;  3LTG D;  1LMJ A;  1ATA A;  3KQE L;  4RS0 A;  1CX2 A;  5L2Y L;  3CS7 L;  4Y71 B;  4TGF A;  1HT8 A;  3N8Y B;  4O1Z A;  1WHE A;  4D0F A;  1X7A L;  1P0S L;  4BDX A;  1XKA L;  5JB8 E;  5IKR A;  3ZYJ B;  1PTH A;  1EPJ A;  3ELA L;  2Y5F L;  5F1A A;  4X8V L;  4LMF A; 
#chains in the Genus database with same CATH topology
 1G2M B;  5CKM A;  1C5M F;  1CVW L;  2Y80 B;  2W3K B;  4D0E A;  3CFW A;  5CIS A;  1G1Q A;  1LPK A;  5KN5 C;  5CKQ A;  1NFU B;  3HO3 A;  3N8V A;  2W2N E;  5L2Z L;  3TH3 L;  5K0H B;  2XBY L;  1F0S B;  1PRH A;  1IQH L;  3MQE A;  2J2U B;  4OTJ A;  3OLU A;  3N8W B;  4ZAE B;  2Y38 A;  1IOX A;  2P3F L;  1KSN B;  1V1H A;  2Q1J B;  2BQ6 A;  1HCG B;  2UWP B;  3HPT A;  1URK A;  1IP0 A;  2W2M E;  1ATB A;  3GCX E;  2VVC K;  1DDX A;  5JVZ A;  3M37 L;  1WU1 B;  1JBU L;  4BXS A;  4CUE A;  3FCS B;  4OTY A;  1LQD A;  4YZU B;  2WG3 C;  2Y82 B;  3K9X A;  4A94 C;  1EQH A;  3KL6 B;  3FBY A;  5JBC E;  1LK9 A;  2K2T A;  1FSB A;  1FJS L;  5E8D A;  1IJQ A;  2P3U A;  4Y6D B;  1HAE A;  2CJI B;  1UZP A;  2OYU P;  1HX2 A;  1KKE A;  3TK5 B;  5IKV A;  3S6X A;  2YGQ A;  3LC5 B;  1PGE A;  2RHP A;  3U73 A;  3NJP C;  2XBX L;  6COX A;  5KIR A;  2P28 B;  1WHF A;  1K36 A;  2MGR A;  2J95 B;  1Z6E L;  2KL7 A;  1FAK L;  4BTU A;  2XC4 L;  2YGO A;  1PXX A;  5IKT A;  1EPH A;  3LAQ A;  2BZ6 L;  1IQF L;  2XC0 L;  3F6U L;  2P95 L;  4E1G A;  2W3I B;  2Y81 B;  4G1M B;  4LOR A;  4RRZ A;  1EPI A;  1F7M A;  1O5D L;  4MMX B;  1YUG A;  2WG4 B;  1CCF A;  1NQL B;  1ATD A;  4NG9 L;  4BDW A;  3IIT B;  1KIG L;  5JBA E;  2D1J B;  2VWL L;  3N8Z A;  2P94 L;  2WPL E;  4RRY A;  3ZYI B;  4ZH8 B;  1UZQ A;  4BTI A;  3Q3K B;  1CQE A;  2BO2 A;  5CKN A;  1AUT L;  2Y5H L;  3RR3 A;  1XFE A;  2W2Q E;  5FDQ A;  2W2O E;  1BF9 A;  2M74 A;  2P3T A;  4FM5 A;  1SZB A;  1DIY A;  1W7X L;  2PUQ L;  3KQD L;  3F1S B;  1OB1 C;  1LMM A;  1APO A;  2VRS A;  1RFN B;  2VVV L;  1TLE A;  4GU3 A;  1JL9 A;  3IJE B;  1APQ A;  3KRK A;  4JYV L;  1NFW B;  3QH0 A;  1W8B L;  1G2L B;  2P16 L;  1G1S A;  2H9E L;  1QIU A;  3HS5 A;  1EZQ B;  1N7D A;  3SOQ A;  1NT0 A;  3V65 B;  5JW1 A;  1XKB A;  2NPR A;  1K37 A;  2W2P E;  3SOB B;  1FAX L;  1NPE B;  2MHP A;  1NFY B;  5JBB E;  2VJ3 A;  1MQ5 L;  4Z0L A;  1YO8 A;  4JYU L;  3LN1 A;  3LTF B;  1HRE A;  3KK6 A;  2EI8 B;  3POY A;  2Y7X B;  1P9J A;  2BT8 A;  1EBV A;  1I0U A;  2BT7 A;  2FD6 A;  1IGZ A;  1FE2 A;  4D90 A;  4ZHA B;  4Y76 B;  5IKQ A;  4Z0K B;  1YGC L;  4ISH L;  2P3F N;  2P93 L;  1UZK A;  1U67 A;  2BSF A;  2K2S B;  3HO4 A;  1JV2 B;  2WPJ E;  4C16 A;  2GD4 A;  4NGA L;  3N8Y A;  2WZP P;  2AYL A;  1HRF A;  2J4I B;  2I9B A;  4XLW A;  1IQG L;  1IQE L;  4YT7 L;  3MDL A;  1F0R B;  4AQT A;  4BTT A;  2VWN L;  4JZF L;  3ZYG A;  1J9C L;  4RRW A;  4M11 A;  2PHB B;  3SOV A;  2XC5 L;  4M10 A;  1IQL L;  3OLT A;  3TBD A;  2WPM E;  5I46 L;  3GIS X;  4X8S L;  3NT1 A;  1EPG A;  3M36 L;  2J94 B;  2JKH L;  1MOX C;  1IOE L;  3C9A C;  3BPS E;  3KQB L;  4NA9 L;  1XDT R;  2J38 B;  3HS7 A;  2FLB L;  2VVU L;  1HZ8 A;  1DX5 I;  2VH0 B;  2WPK E;  2OYE P;  2DDU A;  1F7E A;  3EGF A;  2WFX B;  1LPZ A;  2KB9 A;  1YUF A;  1TPG A;  3BT2 A;  1FFM A;  5F19 A;  3U7U G;  1EQG A;  3N8W A;  2UWL B;  4XL1 A;  2VH6 B;  2Y7Z B;  1V3X B;  2ADX A;  4ISI L;  1ZAQ A;  1EMO A;  2XBW L;  3NTG A;  1IVO C;  2WPI E;  1KLO A;  2WYJ B;  4MMY B;  3LC3 B;  1G1R A;  3FFG L;  3GCW E;  2WYG B;  3V64 C;  1ATE A;  1NFX B;  3HS6 A;  1EAI C;  2FLR L;  1HAF A;  1M1X B;  1CCV A;  2HOX A;  3CA7 A;  2KV4 A;  1HJ7 A;  2JJL A;  3BT1 A;  4JZD L;  1YUK B;  1B9W A;  4COX A;  4Z6A L;  1IQN L;  2TGF A;  4ZXY L;  4BXW A;  1G1T A;  4CUD A;  3PGH A;  2BQ7 A;  1KLJ L;  5JVY A;  2BOK L;  1UZJ A;  2W26 B;  2J34 B;  5L30 L;  3Q7D A;  3ENS A;  2B7D L;  1CVU A;  2MGP A;  2VWO L;  4RUT A;  2EI7 B;  2HOR A;  3NTB A;  1COU A;  5COX A;  1FF7 A;  1DVA L;  2RA0 L;  1IGX A;  1NZI A;  1Z6C A;  3DEM A;  2P26 A;  4X8T L;  3N8X A;  4ZXX L;  2FZZ L;  2G00 L;  4A7I A;  1CEJ A;  2BQW A;  4Y79 B;  2YGP A;  1DQB A;  2I9A A;  3ASI A;  2BOX A;  1MQ6 L;  2BOH A;  3TK6 B;  3KQC L;  2EI6 B;  3CEN L;  2WPH E;  4GU4 A;  4O02 B;  2F9B L;  2BMG A;  3QCW A;  1Q4G A;  4MMZ B;  1EMN A;  2WFT A;  1TOZ A;  1IQJ L;  1IQK L;  2BOU A;  3LN0 A;  5JB9 E;  3KCG L;  3SW2 A;  1PFX L;  3R05 A;  4X8U L;  1U8C B;  2FLG A;  4CSY A;  3HO5 A;  1EGF A;  4RRX A;  1L3Y A;  1ADX A;  3LIW B;  4JZE L;  5EGM B;  2Y5G L;  2VWM K;  3QMO A;  1GK5 A;  1N1I A;  1HT5 A;  3P5B L;  2UWO B;  1IQM L;  4XBM A;  1LPG A;  4Y7A B;  3TZI A;  1QFK L;  4CUF A;  1A3P A;  4PH9 A;  1IQI L;  2PR3 B;  1KLI L;  2RNL A;  3H5C B;  2H9E C;  4Y7B B;  2W86 A;  2XBV L;  1L5G B;  3TGF A;  4YT6 L;  3LTG D;  1LMJ A;  1ATA A;  3KQE L;  4RS0 A;  1CX2 A;  5L2Y L;  3CS7 L;  4Y71 B;  1V1I A;  2KNI A;  4TGF A;  1HT8 A;  3N8Y B;  4O1Z A;  1WHE A;  4D0F A;  1X7A L;  1P0S L;  4BDX A;  1XKA L;  5JB8 E;  5IKR A;  3ZYJ B;  1PTH A;  1EPJ A;  3ELA L;  2Y5F L;  5F1A A;  4X8V L;  4LMF A; 
#chains in the Genus database with same CATH homology
 1G2M B;  5CKM A;  1C5M F;  1CVW L;  2Y80 B;  2W3K B;  4D0E A;  3CFW A;  5CIS A;  1G1Q A;  1LPK A;  5KN5 C;  5CKQ A;  1NFU B;  3HO3 A;  3N8V A;  2W2N E;  5L2Z L;  3TH3 L;  5K0H B;  2XBY L;  1F0S B;  1PRH A;  1IQH L;  3MQE A;  2J2U B;  4OTJ A;  3OLU A;  3N8W B;  4ZAE B;  2Y38 A;  1IOX A;  2P3F L;  1KSN B;  2Q1J B;  2BQ6 A;  1HCG B;  2UWP B;  3HPT A;  1URK A;  1IP0 A;  2W2M E;  1ATB A;  3GCX E;  2VVC K;  1DDX A;  5JVZ A;  3M37 L;  1WU1 B;  1JBU L;  4BXS A;  4CUE A;  3FCS B;  4OTY A;  1LQD A;  4YZU B;  2WG3 C;  2Y82 B;  3K9X A;  4A94 C;  1EQH A;  3KL6 B;  3FBY A;  5JBC E;  2K2T A;  1FSB A;  1FJS L;  5E8D A;  1IJQ A;  2P3U A;  4Y6D B;  1HAE A;  2CJI B;  1UZP A;  2OYU P;  1HX2 A;  3TK5 B;  5IKV A;  3S6X A;  2YGQ A;  3LC5 B;  1PGE A;  2RHP A;  3U73 A;  3NJP C;  2XBX L;  6COX A;  5KIR A;  2P28 B;  1WHF A;  1K36 A;  2MGR A;  2J95 B;  1Z6E L;  2KL7 A;  1FAK L;  4BTU A;  2XC4 L;  2YGO A;  1PXX A;  5IKT A;  1EPH A;  3LAQ A;  2BZ6 L;  1IQF L;  2XC0 L;  3F6U L;  2P95 L;  4E1G A;  2W3I B;  2Y81 B;  4G1M B;  4LOR A;  4RRZ A;  1EPI A;  1F7M A;  1O5D L;  4MMX B;  1YUG A;  2WG4 B;  1CCF A;  1NQL B;  1ATD A;  4NG9 L;  4BDW A;  3IIT B;  1KIG L;  5JBA E;  2D1J B;  2VWL L;  3N8Z A;  2P94 L;  2WPL E;  4RRY A;  3ZYI B;  4ZH8 B;  1UZQ A;  4BTI A;  3Q3K B;  1CQE A;  2BO2 A;  5CKN A;  1AUT L;  2Y5H L;  3RR3 A;  1XFE A;  2W2Q E;  5FDQ A;  2W2O E;  1BF9 A;  2M74 A;  2P3T A;  4FM5 A;  1SZB A;  1DIY A;  1W7X L;  2PUQ L;  3KQD L;  3F1S B;  1OB1 C;  1LMM A;  1APO A;  1RFN B;  2VVV L;  1TLE A;  1JL9 A;  3IJE B;  1APQ A;  3KRK A;  4JYV L;  1NFW B;  3QH0 A;  1W8B L;  1G2L B;  2P16 L;  1G1S A;  2H9E L;  3HS5 A;  1EZQ B;  1N7D A;  3SOQ A;  1NT0 A;  3V65 B;  5JW1 A;  1XKB A;  2NPR A;  1K37 A;  2W2P E;  3SOB B;  1FAX L;  1NPE B;  2MHP A;  1NFY B;  5JBB E;  2VJ3 A;  1MQ5 L;  4Z0L A;  1YO8 A;  4JYU L;  3LN1 A;  3LTF B;  1HRE A;  3KK6 A;  2EI8 B;  3POY A;  2Y7X B;  1P9J A;  1EBV A;  1I0U A;  2FD6 A;  1IGZ A;  1FE2 A;  4D90 A;  4ZHA B;  4Y76 B;  5IKQ A;  4Z0K B;  1YGC L;  4ISH L;  2P3F N;  2P93 L;  1UZK A;  1U67 A;  3HO4 A;  2K2S B;  1JV2 B;  2WPJ E;  4C16 A;  2GD4 A;  4NGA L;  3N8Y A;  2WZP P;  2AYL A;  1HRF A;  2J4I B;  2I9B A;  4XLW A;  1IQG L;  1IQE L;  4YT7 L;  3MDL A;  1F0R B;  4AQT A;  4BTT A;  2VWN L;  4JZF L;  3ZYG A;  1J9C L;  4RRW A;  4M11 A;  2PHB B;  3SOV A;  2XC5 L;  4M10 A;  1IQL L;  3OLT A;  3TBD A;  2WPM E;  5I46 L;  3GIS X;  4X8S L;  3NT1 A;  1EPG A;  3M36 L;  2J94 B;  2JKH L;  1MOX C;  1IOE L;  3C9A C;  3BPS E;  3KQB L;  4NA9 L;  1XDT R;  2J38 B;  3HS7 A;  2FLB L;  2VVU L;  1HZ8 A;  1DX5 I;  2VH0 B;  2WPK E;  2OYE P;  2DDU A;  1F7E A;  3EGF A;  2WFX B;  1LPZ A;  2KB9 A;  1YUF A;  1TPG A;  3BT2 A;  1FFM A;  5F19 A;  3U7U G;  1EQG A;  3N8W A;  2UWL B;  4XL1 A;  2VH6 B;  2Y7Z B;  1V3X B;  2ADX A;  4ISI L;  1ZAQ A;  1EMO A;  2XBW L;  3NTG A;  1IVO C;  2WPI E;  1KLO A;  2WYJ B;  4MMY B;  3LC3 B;  1G1R A;  3FFG L;  3GCW E;  2WYG B;  3V64 C;  1ATE A;  1NFX B;  3HS6 A;  1EAI C;  2FLR L;  1HAF A;  1M1X B;  1CCV A;  3CA7 A;  2KV4 A;  1HJ7 A;  3BT1 A;  4JZD L;  1YUK B;  1B9W A;  4COX A;  4Z6A L;  1IQN L;  2TGF A;  4ZXY L;  4BXW A;  1G1T A;  4CUD A;  3PGH A;  2BQ7 A;  1KLJ L;  5JVY A;  2BOK L;  1UZJ A;  2W26 B;  2J34 B;  5L30 L;  3Q7D A;  3ENS A;  2B7D L;  1CVU A;  2MGP A;  2VWO L;  4RUT A;  2EI7 B;  3NTB A;  1COU A;  5COX A;  1FF7 A;  1DVA L;  2RA0 L;  1IGX A;  1NZI A;  1Z6C A;  3DEM A;  2P26 A;  4X8T L;  3N8X A;  4ZXX L;  2FZZ L;  2G00 L;  4A7I A;  1CEJ A;  2BQW A;  4Y79 B;  2YGP A;  1DQB A;  2I9A A;  3ASI A;  2BOX A;  1MQ6 L;  2BOH A;  3TK6 B;  3KQC L;  2EI6 B;  3CEN L;  2WPH E;  4O02 B;  2F9B L;  2BMG A;  3QCW A;  1Q4G A;  4MMZ B;  1EMN A;  2WFT A;  1TOZ A;  1IQJ L;  1IQK L;  2BOU A;  3LN0 A;  5JB9 E;  3KCG L;  3SW2 A;  1PFX L;  3R05 A;  4X8U L;  1U8C B;  2FLG A;  4CSY A;  3HO5 A;  1EGF A;  4RRX A;  1L3Y A;  1ADX A;  3LIW B;  4JZE L;  5EGM B;  2Y5G L;  2VWM K;  3QMO A;  1GK5 A;  1N1I A;  1HT5 A;  3P5B L;  2UWO B;  1IQM L;  4XBM A;  1LPG A;  4Y7A B;  3TZI A;  1QFK L;  4CUF A;  1A3P A;  4PH9 A;  1IQI L;  2PR3 B;  1KLI L;  2RNL A;  3H5C B;  2H9E C;  4Y7B B;  2W86 A;  2XBV L;  1L5G B;  3TGF A;  4YT6 L;  3LTG D;  1LMJ A;  1ATA A;  3KQE L;  4RS0 A;  1CX2 A;  5L2Y L;  3CS7 L;  4Y71 B;  2KNI A;  4TGF A;  1HT8 A;  3N8Y B;  4O1Z A;  1WHE A;  4D0F A;  1X7A L;  1P0S L;  4BDX A;  1XKA L;  5JB8 E;  5IKR A;  3ZYJ B;  1PTH A;  1EPJ A;  3ELA L;  2Y5F L;  5F1A A;  4X8V L;  4LMF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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