3GISX

Crystal structure of na-free thrombin in complex with thrombomodulin
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
115
structure length
113
Chain Sequence
DPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQLFCNQTACPADCDPNASCECPEGYILDDGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSALAGQIGTDCD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Blood clotting
source organism Homo sapiens
publication title Molecular basis of thrombomodulin activation of slow thrombin
pubmed doi rcsb
molecule keywords Prothrombin
total genus 15
structure length 113
sequence length 115
chains with identical sequence Y, Z
ec nomenclature
pdb deposition date 2009-03-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3gisX01
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3gisX03
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3gisX02
4Z0KB 4E1GA 3ENSA 3TBDA 2BOKL 2I9BA 2KL7A 4BDWA 1FSBA 4X8SL 1MQ5L 3BT2A 1EQHA 4AQTA 2VH6B 4Z0LA 2Q1JB 3KQBL 3ZYJB 1UZPA 1L5GB 4X8UL 2Y80B 3TH3L 1ATEA 4RRWA 1IQKL 3M36L 3HO4A 4BDXA 2YGOA 3OLTA 1IOXA 1IQEL 4LORA 3GISX 4ZXXL 4Y71B 1GK5A 3NT1A 2P3FN 3HS6A 2J95B 1LMJA 2G00L 2RA0L 4O02B 1FAKL 4ZHAB 1EZQB 3K9XA 2OYUP 2WYJB 1YUFA 1G2LB 2AYLA 4Y76B 4CSYA 2VVCK 2JKHL 2P94L 3NJPC 4MMXB 4D0EA 2WFTA 5JB8E 3LN1A 5IKTA 1EPGA 3TK6B 1IQFL 1DX5I 3KCGL 1XFEA 1XDTR 2WYGB 2ADXA 2WPME 2BZ6L 5COXA 2CJIB 2XC4L 4ISHL 3R05A 1IQIL 5CKMA 5KN5C 5JVZA 1XKBA 1DIYA 1FE2A 1JV2B 1CCVA 4JYVL 4BTTA 2VVVL 3GCXE 4CUEA 4Z6AL 1CVUA 5I46L 2J34B 2W86A 2BQWA 2Y38A 3FFGL 3MQEA 4RRXA 5K0HB 2D1JB 4CUFA 4MMYB 1WU1B 2P3UA 2WPIE 1KLOA 4X8TL 2PR3B 1UZKA 2GD4A 1LPZA 3N8XA 5IKVA 2XBWL 4JZEL 2UWLB 1PFXL 4XL1A 1EGFA 2RNLA 2W2QE 1AUTL 1COUA 1IQHL 1IQLL 1KLJL 1NPEB 2VJ3A 2EI8B 3HS5A 1IQGL 4LMFA 1PRHA 4Y6DB 2NPRA 4RUTA 3C9AC 3KQDL 1Z6EL 1P9JA 3KQEL 3M37L 1KLIL 3RR3A 3QMOA 1EMNA 2VH0B 2Y7XB 2P16L 1FJSL 5F1AA 3V65B 1PGEA 3SOBB 1IQNL 5CKQA 1DQBA 2DDUA 4COXA 1M1XB 3GCWE 2P95L 2Y7ZB 1HX2A 3LC5B 2WPLE 2P3TA 1I0UA 1NT0A 2P93L 4OTYA 2VWMK 2PUQL 3V64C 1NFUB 5JBBE 3TZIA 4ZXYL 2WG4B 4BTIA 2YGPA 3CS7L 4NG9L 3NTGA 4RRYA 3POYA 2P28B 3KL6B 2VWOL 1TLEA 3BPSE 4M10A 3HPTA 3PGHA 4FM5A 4MMZB 1G1SA 3OLUA 4XLWA 5IKRA 1URKA 1NFWB 4M11A 4Y79B 2J4IB 1YO8A 2BOHA 1G2MB 1HREA 1F7EA 2WPJE 3IITB 1LPGA 3ELAL 4NA9L 5E8DA 4YT7L 1C5MF 3F1SB 1HCGB 2Y81B 1UZQA 3KRKA 4YZUB 3ZYIB 1MQ6L 2P26A 3N8YB 2OYEP 4JZDL 2EI7B 1W8BL 2VWLL 4Y7AB 2BOXA 1APOA 4JYUL 2W2ME 3P5BL 2W2NE 2XBXL 1F7MA 1WHEA 2K2SB 2Y5FL 3BT1A 1UZJA 2B7DL 2WPKE 1F0SB 4BTUA 5JBCE 3FCSB 3Q7DA 3CENL 1NZIA 1YGCL 4Y7BB 2W3KB 1K37A 1WHFA 2Y5GL 3ZYGA 3U7UG 3HS7A 2W26B 5JVYA 2MGPA 2Y82B 3LTGD 1EPIA 2BOUA 2KB9A 2RHPA 3LIWB 1FF7A 1U67A 5L2ZL 1CQEA 1IGXA 1Q4GA 4G1MB 3LAQA 2XBVL 1JL9A 5CKNA 1EPHA 2BO2A 4BXSA 3EGFA 2MGRA 4TGFA 1JBUL 1HT5A 4ZAEB 5FDQA 1CVWL 1EBVA 1ADXA 3HO5A 2H9EL 1U8CB 1CEJA 5IKQA 1W7XL 3FBYA 2EI6B 3LN0A 4YT6L 2BQ7A 3N8ZA 1L3YA 4OTJA 3CFWA 3QCWA 4X8VL 1CCFA 4D90A 1SZBA 4ISIL 4O1ZA 2J94B 1LPKA 4XBMA 1FFMA 2FLGA 1EPJA 4CUDA 3N8YA 2TGFA 5L30L 5CISA 1NFYB 3KK6A 1V3XB 3F6UL 2P3FL 2W2PE 1F0RB 5L2YL 1B9WA 2FZZL 2J38B 1HAEA 1MOXC 3KQCL 1TPGA 2WG3C 1IQJL 2VWNL 3IJEB 1IGZA 2Y5HL 5F19A 4RS0A 1HZ8A 5EGMB 2XC0L 3LC3B 1HAFA 3SOQA 1IP0A 2BMGA 1BF9A 2W3IB 3NTBA 1IVOC 1TOZA 2UWPB 1A3PA 2F9BL 1IOEL 4ZH8B 2FLRL 3H5CB 1K36A 6COXA 1IJQA 2FLBL 1Z6CA 4A7IA 2VVUL 2XBYL 1DVAL 3TK5B 1IQML 3SW2A 5JBAE 4NGAL 1OB1C 4D0FA 2WPHE 1ATAA 4JZFL 1G1TA 1FAXL 3N8VA 5JW1A 1YUKB 3N8WA 1N7DA 2WFXB 1PXXA 1RFNB 1DDXA 1APQA 2J2UB 1XKAL 4BXWA 2K2TA 2M74A 1X7AL 2XC5L 2FD6A 1ZAQA 2BQ6A 4RRZA 1ATBA 2I9AA 1LQDA 1J9CL 3DEMA 5KIRA 1HT8A 2PHBB 1O5DL 1KSNB 2UWOB 1HRFA 4PH9A 3N8WB 1HJ7A 1EAIC 1G1QA 3QH0A 1EMOA 1ATDA 1NFXB 1PTHA 3HO3A 3MDLA 2KV4A 5JB9E 3ASIA 1CX2A 1YUGA 1EQGA 1N1IA 3Q3KB 1NQLB 2W2OE 1KIGL 3CA7A 3LTFB 4C16A 2MHPA 3U73A 3TGFA 3SOVA 1P0SL 1QFKL 1G1RA
chains in the Genus database with same CATH superfamily
4Z0KB 4E1GA 3ENSA 3TBDA 2BOKL 2I9BA 2KL7A 4BDWA 1FSBA 4X8SL 2HOXA 1MQ5L 3BT2A 1EQHA 4AQTA 2VH6B 4Z0LA 2Q1JB 3KQBL 3ZYJB 4A94C 1UZPA 1L5GB 4X8UL 2Y80B 3TH3L 1ATEA 4RRWA 1IQKL 3M36L 3HO4A 2WZPP 4BDXA 2YGOA 2VRSA 3OLTA 1IOXA 1IQEL 4LORA 3GISX 4ZXXL 4Y71B 1GK5A 3NT1A 2P3FN 3HS6A 2J95B 1LMJA 2G00L 2RA0L 4O02B 1FAKL 4ZHAB 1EZQB 3K9XA 2OYUP 2WYJB 1YUFA 1G2LB 2AYLA 4Y76B 4CSYA 2VVCK 2JKHL 2P94L 3NJPC 4MMXB 4D0EA 2WFTA 5JB8E 3LN1A 5IKTA 1EPGA 3TK6B 1IQFL 1DX5I 3KCGL 1XFEA 1XDTR 2WYGB 2ADXA 2WPME 2BZ6L 5COXA 2CJIB 2XC4L 4ISHL 3R05A 1IQIL 5CKMA 5KN5C 5JVZA 1XKBA 1DIYA 3S6XA 1FE2A 1JV2B 1CCVA 4JYVL 4BTTA 2VVVL 3GCXE 4CUEA 4Z6AL 1CVUA 5I46L 2J34B 2W86A 2BQWA 2Y38A 1V1HA 3FFGL 3MQEA 4RRXA 5K0HB 2D1JB 4CUFA 1LMMA 4MMYB 1WU1B 2P3UA 2WPIE 1KLOA 4X8TL 2PR3B 1UZKA 2GD4A 1LPZA 3N8XA 5IKVA 2XBWL 4JZEL 2UWLB 1PFXL 4XL1A 1EGFA 2RNLA 2W2QE 1AUTL 1COUA 1IQHL 1IQLL 1KLJL 1NPEB 2VJ3A 2EI8B 3HS5A 1IQGL 4LMFA 1PRHA 4Y6DB 2NPRA 4RUTA 3C9AC 3KQDL 1Z6EL 1P9JA 3KQEL 3M37L 1KLIL 3RR3A 3QMOA 1EMNA 2VH0B 2Y7XB 2P16L 1FJSL 5F1AA 3V65B 1PGEA 3SOBB 1IQNL 5CKQA 1DQBA 2DDUA 4COXA 1M1XB 3GCWE 2P95L 2Y7ZB 1HX2A 3LC5B 4GU4A 2WPLE 2P3TA 1I0UA 1NT0A 2P93L 4OTYA 2VWMK 2PUQL 3V64C 1NFUB 5JBBE 3TZIA 4ZXYL 2WG4B 4BTIA 2YGPA 3CS7L 4NG9L 3NTGA 4RRYA 3POYA 2P28B 2BSFA 3KL6B 2VWOL 1TLEA 3BPSE 4M10A 3HPTA 3PGHA 4FM5A 4MMZB 1G1SA 3OLUA 4XLWA 1QIUA 5IKRA 1URKA 1NFWB 4M11A 4Y79B 2J4IB 1YO8A 2BOHA 1G2MB 1HREA 1F7EA 2WPJE 3IITB 1LPGA 3ELAL 4NA9L 5E8DA 4GU3A 4YT7L 1C5MF 3F1SB 1HCGB 2Y81B 1UZQA 3KRKA 4YZUB 3ZYIB 1MQ6L 2P26A 3N8YB 2OYEP 4JZDL 2EI7B 1W8BL 2VWLL 4Y7AB 2BOXA 1APOA 4JYUL 2W2ME 3P5BL 2W2NE 2XBXL 1F7MA 1WHEA 2K2SB 2Y5FL 3BT1A 1UZJA 2B7DL 2WPKE 1F0SB 4BTUA 5JBCE 3FCSB 3Q7DA 3CENL 1NZIA 1YGCL 4Y7BB 2W3KB 1K37A 1WHFA 2Y5GL 3ZYGA 3U7UG 3HS7A 2W26B 5JVYA 2MGPA 2Y82B 3LTGD 1EPIA 2BOUA 2KB9A 2RHPA 3LIWB 1FF7A 1U67A 5L2ZL 1CQEA 1IGXA 1Q4GA 4G1MB 3LAQA 2XBVL 1JL9A 5CKNA 1EPHA 2BO2A 4BXSA 3EGFA 2MGRA 4TGFA 1JBUL 1HT5A 4ZAEB 5FDQA 1CVWL 1EBVA 1ADXA 3HO5A 2H9EL 1U8CB 1CEJA 5IKQA 1W7XL 3FBYA 2EI6B 3LN0A 4YT6L 2BQ7A 3N8ZA 1L3YA 4OTJA 3CFWA 3QCWA 4X8VL 1CCFA 4D90A 1SZBA 4ISIL 4O1ZA 2J94B 1LPKA 4XBMA 1FFMA 2FLGA 1EPJA 4CUDA 3N8YA 2TGFA 5L30L 5CISA 1NFYB 3KK6A 1V3XB 3F6UL 2P3FL 2HORA 2W2PE 1F0RB 5L2YL 1B9WA 2FZZL 2J38B 1HAEA 1MOXC 3KQCL 1TPGA 2WG3C 1IQJL 2VWNL 3IJEB 1IGZA 1V1IA 2Y5HL 5F19A 4RS0A 1HZ8A 5EGMB 2XC0L 3LC3B 1HAFA 3SOQA 1IP0A 2BMGA 1BF9A 2W3IB 3NTBA 1IVOC 1TOZA 2UWPB 1A3PA 2F9BL 1IOEL 4ZH8B 2FLRL 2YGQA 3H5CB 1K36A 6COXA 1IJQA 2FLBL 1Z6CA 4A7IA 2VVUL 2XBYL 1DVAL 3TK5B 1IQML 3SW2A 5JBAE 4NGAL 1OB1C 4D0FA 2WPHE 1ATAA 4JZFL 1G1TA 1FAXL 3N8VA 2H9EC 5JW1A 1YUKB 3N8WA 1N7DA 2WFXB 1PXXA 2JJLA 1RFNB 1DDXA 1APQA 2J2UB 1XKAL 4BXWA 2K2TA 2M74A 1X7AL 2XC5L 1KKEA 2FD6A 1ZAQA 2BQ6A 4RRZA 1ATBA 2I9AA 2KNIA 1LQDA 1J9CL 3DEMA 5KIRA 1HT8A 2PHBB 1O5DL 1KSNB 2UWOB 1HRFA 4PH9A 3N8WB 1HJ7A 1EAIC 1G1QA 1LK9A 3QH0A 1EMOA 2BT7A 1NFXB 1PTHA 3HO3A 3MDLA 1ATDA 2KV4A 5JB9E 3ASIA 1CX2A 1YUGA 1EQGA 1N1IA 3Q3KB 1NQLB 2W2OE 1KIGL 3CA7A 3LTFB 4C16A 2MHPA 3U73A 2BT8A 3TGFA 3SOVA 1P0SL 1QFKL 1G1RA
chains in the Genus database with same CATH topology
4Z0KB 4E1GA 3ENSA 3TBDA 2BOKL 2I9BA 2KL7A 4BDWA 1FSBA 4X8SL 1MQ5L 3BT2A 1EQHA 4AQTA 2VH6B 4Z0LA 2Q1JB 3KQBL 3ZYJB 4A94C 1UZPA 1L5GB 4X8UL 2Y80B 3TH3L 1ATEA 4RRWA 1IQKL 3M36L 3HO4A 2WZPP 4BDXA 2YGOA 3OLTA 1IOXA 1IQEL 4LORA 3GISX 4ZXXL 4Y71B 1GK5A 3NT1A 2P3FN 3HS6A 2J95B 1LMJA 2G00L 2RA0L 4O02B 1FAKL 4ZHAB 1EZQB 3K9XA 2OYUP 2WYJB 1YUFA 1G2LB 2AYLA 4Y76B 4CSYA 2VVCK 2JKHL 2P94L 3NJPC 4MMXB 4D0EA 2WFTA 5JB8E 3LN1A 5IKTA 1EPGA 3TK6B 1IQFL 1DX5I 3KCGL 1XFEA 1XDTR 2WYGB 2ADXA 2WPME 2BZ6L 5COXA 2CJIB 2XC4L 4ISHL 3R05A 1IQIL 5CKMA 5KN5C 5JVZA 1XKBA 1DIYA 3S6XA 1FE2A 1JV2B 1CCVA 4JYVL 4BTTA 2VVVL 3GCXE 4CUEA 4Z6AL 1CVUA 5I46L 2J34B 2W86A 2BQWA 2Y38A 3FFGL 3MQEA 4RRXA 5K0HB 2D1JB 4CUFA 1LMMA 4MMYB 1WU1B 2P3UA 2WPIE 1KLOA 4X8TL 2PR3B 1UZKA 2GD4A 1LPZA 3N8XA 5IKVA 2XBWL 4JZEL 2UWLB 1PFXL 4XL1A 1EGFA 2RNLA 2W2QE 1AUTL 1COUA 1IQHL 1IQLL 1KLJL 1NPEB 2VJ3A 2EI8B 3HS5A 1IQGL 4LMFA 1PRHA 4Y6DB 2NPRA 4RUTA 3C9AC 3KQDL 1Z6EL 1P9JA 3KQEL 3M37L 1KLIL 3RR3A 3QMOA 1EMNA 2VH0B 2Y7XB 2P16L 1FJSL 5F1AA 3V65B 1PGEA 3SOBB 1IQNL 5CKQA 1DQBA 2DDUA 4COXA 1M1XB 3GCWE 2P95L 2Y7ZB 1HX2A 3LC5B 2WPLE 2P3TA 1I0UA 1NT0A 2P93L 4OTYA 2VWMK 2PUQL 3V64C 1NFUB 5JBBE 3TZIA 4ZXYL 2WG4B 4BTIA 2YGPA 3CS7L 4NG9L 3NTGA 4RRYA 3POYA 2P28B 3KL6B 2VWOL 1TLEA 3BPSE 4M10A 3HPTA 3PGHA 4FM5A 4MMZB 1G1SA 3OLUA 4XLWA 5IKRA 1URKA 1NFWB 4M11A 4Y79B 2J4IB 1YO8A 2BOHA 1G2MB 1HREA 1F7EA 2WPJE 3IITB 1LPGA 3ELAL 4NA9L 5E8DA 4YT7L 1C5MF 3F1SB 1HCGB 2Y81B 1UZQA 3KRKA 4YZUB 3ZYIB 1MQ6L 2P26A 3N8YB 2OYEP 4JZDL 2EI7B 1W8BL 2VWLL 4Y7AB 2BOXA 1APOA 4JYUL 2W2ME 3P5BL 2W2NE 2XBXL 1F7MA 1WHEA 2K2SB 2Y5FL 3BT1A 1UZJA 2B7DL 2WPKE 1F0SB 4BTUA 5JBCE 3FCSB 3Q7DA 3CENL 1NZIA 1YGCL 4Y7BB 2W3KB 1K37A 1WHFA 2Y5GL 3ZYGA 3U7UG 3HS7A 2W26B 5JVYA 2MGPA 2Y82B 3LTGD 1EPIA 2BOUA 2KB9A 2RHPA 3LIWB 1FF7A 1U67A 5L2ZL 1CQEA 1IGXA 1Q4GA 4G1MB 3LAQA 2XBVL 1JL9A 5CKNA 1EPHA 2BO2A 4BXSA 3EGFA 2MGRA 4TGFA 1JBUL 1HT5A 4ZAEB 5FDQA 1CVWL 1EBVA 1ADXA 3HO5A 2H9EL 1U8CB 1CEJA 5IKQA 1W7XL 3FBYA 2EI6B 3LN0A 4YT6L 2BQ7A 3N8ZA 1L3YA 4OTJA 3CFWA 3QCWA 4X8VL 1CCFA 4D90A 1SZBA 4ISIL 4O1ZA 2J94B 1LPKA 4XBMA 1FFMA 2FLGA 1EPJA 4CUDA 3N8YA 2TGFA 5L30L 5CISA 1NFYB 3KK6A 1V3XB 3F6UL 2P3FL 2W2PE 1F0RB 5L2YL 1B9WA 2FZZL 2J38B 1HAEA 1MOXC 3KQCL 1TPGA 2WG3C 1IQJL 2VWNL 3IJEB 1IGZA 2Y5HL 5F19A 4RS0A 1HZ8A 5EGMB 2XC0L 3LC3B 1HAFA 3SOQA 1IP0A 2BMGA 1BF9A 2W3IB 3NTBA 1IVOC 1TOZA 2UWPB 1A3PA 2F9BL 1IOEL 4ZH8B 2FLRL 2YGQA 3H5CB 1K36A 6COXA 1IJQA 2FLBL 1Z6CA 4A7IA 2VVUL 2XBYL 1DVAL 3TK5B 1IQML 3SW2A 5JBAE 4NGAL 1OB1C 4D0FA 2WPHE 1ATAA 4JZFL 1G1TA 1FAXL 3N8VA 2H9EC 5JW1A 1YUKB 3N8WA 1N7DA 2WFXB 1PXXA 1RFNB 1DDXA 1APQA 2J2UB 1XKAL 4BXWA 2K2TA 2M74A 1X7AL 2XC5L 2FD6A 1ZAQA 2BQ6A 4RRZA 1ATBA 2I9AA 2KNIA 1LQDA 1J9CL 3DEMA 5KIRA 1HT8A 2PHBB 1O5DL 1KSNB 2UWOB 1HRFA 4PH9A 3N8WB 1HJ7A 1EAIC 1G1QA 3QH0A 1EMOA 1ATDA 1NFXB 1PTHA 3HO3A 3MDLA 2KV4A 5JB9E 3ASIA 1CX2A 1YUGA 1EQGA 1N1IA 3Q3KB 1NQLB 2W2OE 1KIGL 3CA7A 3LTFB 4C16A 2MHPA 3U73A 3TGFA 3SOVA 1P0SL 1QFKL 1G1RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z0K B;  4E1G A;  3ENS A;  3TBD A;  2BOK L;  2I9B A;  2KL7 A;  4BDW A;  1FSB A;  4X8S L;  1MQ5 L;  3BT2 A;  1EQH A;  4AQT A;  2VH6 B;  4Z0L A;  2Q1J B;  3KQB L;  3ZYJ B;  1UZP A;  1L5G B;  4X8U L;  2Y80 B;  3TH3 L;  1ATE A;  4RRW A;  1IQK L;  3M36 L;  3HO4 A;  4BDX A;  2YGO A;  3OLT A;  1IOX A;  1IQE L;  4LOR A;  3GIS X;  4ZXX L;  4Y71 B;  1GK5 A;  3NT1 A;  2P3F N;  3HS6 A;  2J95 B;  1LMJ A;  2G00 L;  2RA0 L;  4O02 B;  1FAK L;  4ZHA B;  1EZQ B;  3K9X A;  2OYU P;  2WYJ B;  1YUF A;  1G2L B;  2AYL A;  4Y76 B;  4CSY A;  2VVC K;  2JKH L;  2P94 L;  3NJP C;  4MMX B;  4D0E A;  2WFT A;  5JB8 E;  3LN1 A;  5IKT A;  1EPG A;  3TK6 B;  1IQF L;  1DX5 I;  3KCG L;  1XFE A;  1XDT R;  2WYG B;  2ADX A;  2WPM E;  2BZ6 L;  5COX A;  2CJI B;  2XC4 L;  4ISH L;  3R05 A;  1IQI L;  5CKM A;  5KN5 C;  5JVZ A;  1XKB A;  1DIY A;  1FE2 A;  1JV2 B;  1CCV A;  4JYV L;  4BTT A;  2VVV L;  3GCX E;  4CUE A;  4Z6A L;  1CVU A;  5I46 L;  2J34 B;  2W86 A;  2BQW A;  2Y38 A;  3FFG L;  3MQE A;  4RRX A;  5K0H B;  2D1J B;  4CUF A;  4MMY B;  1WU1 B;  2P3U A;  2WPI E;  1KLO A;  4X8T L;  2PR3 B;  1UZK A;  2GD4 A;  1LPZ A;  3N8X A;  5IKV A;  2XBW L;  4JZE L;  2UWL B;  1PFX L;  4XL1 A;  1EGF A;  2RNL A;  2W2Q E;  1AUT L;  1COU A;  1IQH L;  1IQL L;  1KLJ L;  1NPE B;  2VJ3 A;  2EI8 B;  3HS5 A;  1IQG L;  4LMF A;  1PRH A;  4Y6D B;  2NPR A;  4RUT A;  3C9A C;  3KQD L;  1Z6E L;  1P9J A;  3KQE L;  3M37 L;  1KLI L;  3RR3 A;  3QMO A;  1EMN A;  2VH0 B;  2Y7X B;  2P16 L;  1FJS L;  5F1A A;  3V65 B;  1PGE A;  3SOB B;  1IQN L;  5CKQ A;  1DQB A;  2DDU A;  4COX A;  1M1X B;  3GCW E;  2P95 L;  2Y7Z B;  1HX2 A;  3LC5 B;  2WPL E;  2P3T A;  1I0U A;  1NT0 A;  2P93 L;  4OTY A;  2VWM K;  2PUQ L;  3V64 C;  1NFU B;  5JBB E;  3TZI A;  4ZXY L;  2WG4 B;  4BTI A;  2YGP A;  3CS7 L;  4NG9 L;  3NTG A;  4RRY A;  3POY A;  2P28 B;  3KL6 B;  2VWO L;  1TLE A;  3BPS E;  4M10 A;  3HPT A;  3PGH A;  4FM5 A;  4MMZ B;  1G1S A;  3OLU A;  4XLW A;  5IKR A;  1URK A;  1NFW B;  4M11 A;  4Y79 B;  2J4I B;  1YO8 A;  2BOH A;  1G2M B;  1HRE A;  1F7E A;  2WPJ E;  3IIT B;  1LPG A;  3ELA L;  4NA9 L;  5E8D A;  4YT7 L;  1C5M F;  3F1S B;  1HCG B;  2Y81 B;  1UZQ A;  3KRK A;  4YZU B;  3ZYI B;  1MQ6 L;  2P26 A;  3N8Y B;  2OYE P;  4JZD L;  2EI7 B;  1W8B L;  2VWL L;  4Y7A B;  2BOX A;  1APO A;  4JYU L;  2W2M E;  3P5B L;  2W2N E;  2XBX L;  1F7M A;  1WHE A;  2K2S B;  2Y5F L;  3BT1 A;  1UZJ A;  2B7D L;  2WPK E;  1F0S B;  4BTU A;  5JBC E;  3FCS B;  3Q7D A;  3CEN L;  1NZI A;  1YGC L;  4Y7B B;  2W3K B;  1K37 A;  1WHF A;  2Y5G L;  3ZYG A;  3U7U G;  3HS7 A;  2W26 B;  5JVY A;  2MGP A;  2Y82 B;  3LTG D;  1EPI A;  2BOU A;  2KB9 A;  2RHP A;  3LIW B;  1FF7 A;  1U67 A;  5L2Z L;  1CQE A;  1IGX A;  1Q4G A;  4G1M B;  3LAQ A;  2XBV L;  1JL9 A;  5CKN A;  1EPH A;  2BO2 A;  4BXS A;  3EGF A;  2MGR A;  4TGF A;  1JBU L;  1HT5 A;  4ZAE B;  5FDQ A;  1CVW L;  1EBV A;  1ADX A;  3HO5 A;  2H9E L;  1U8C B;  1CEJ A;  5IKQ A;  1W7X L;  3FBY A;  2EI6 B;  3LN0 A;  4YT6 L;  2BQ7 A;  3N8Z A;  1L3Y A;  4OTJ A;  3CFW A;  3QCW A;  4X8V L;  1CCF A;  4D90 A;  1SZB A;  4ISI L;  4O1Z A;  2J94 B;  1LPK A;  4XBM A;  1FFM A;  2FLG A;  1EPJ A;  4CUD A;  3N8Y A;  2TGF A;  5L30 L;  5CIS A;  1NFY B;  3KK6 A;  1V3X B;  3F6U L;  2P3F L;  2W2P E;  1F0R B;  5L2Y L;  1B9W A;  2FZZ L;  2J38 B;  1HAE A;  1MOX C;  3KQC L;  1TPG A;  2WG3 C;  1IQJ L;  2VWN L;  3IJE B;  1IGZ A;  2Y5H L;  5F19 A;  4RS0 A;  1HZ8 A;  5EGM B;  2XC0 L;  3LC3 B;  1HAF A;  3SOQ A;  1IP0 A;  2BMG A;  1BF9 A;  2W3I B;  3NTB A;  1IVO C;  1TOZ A;  2UWP B;  1A3P A;  2F9B L;  1IOE L;  4ZH8 B;  2FLR L;  3H5C B;  1K36 A;  6COX A;  1IJQ A;  2FLB L;  1Z6C A;  4A7I A;  2VVU L;  2XBY L;  1DVA L;  3TK5 B;  1IQM L;  3SW2 A;  5JBA E;  4NGA L;  1OB1 C;  4D0F A;  2WPH E;  1ATA A;  4JZF L;  1G1T A;  1FAX L;  3N8V A;  5JW1 A;  1YUK B;  3N8W A;  1N7D A;  2WFX B;  1PXX A;  1RFN B;  1DDX A;  1APQ A;  2J2U B;  1XKA L;  4BXW A;  2K2T A;  2M74 A;  1X7A L;  2XC5 L;  2FD6 A;  1ZAQ A;  2BQ6 A;  4RRZ A;  1ATB A;  2I9A A;  1LQD A;  1J9C L;  3DEM A;  5KIR A;  1HT8 A;  2PHB B;  1O5D L;  1KSN B;  2UWO B;  1HRF A;  4PH9 A;  3N8W B;  1HJ7 A;  1EAI C;  1G1Q A;  3QH0 A;  1EMO A;  1ATD A;  1NFX B;  1PTH A;  3HO3 A;  3MDL A;  2KV4 A;  5JB9 E;  3ASI A;  1CX2 A;  1YUG A;  1EQG A;  1N1I A;  3Q3K B;  1NQL B;  2W2O E;  1KIG L;  3CA7 A;  3LTF B;  4C16 A;  2MHP A;  3U73 A;  3TGF A;  3SOV A;  1P0S L;  1QFK L;  1G1R A; 
#chains in the Genus database with same CATH topology
 4Z0K B;  4E1G A;  3ENS A;  3TBD A;  2BOK L;  2I9B A;  2KL7 A;  4BDW A;  1FSB A;  4X8S L;  2HOX A;  1MQ5 L;  3BT2 A;  1EQH A;  4AQT A;  2VH6 B;  4Z0L A;  2Q1J B;  3KQB L;  3ZYJ B;  4A94 C;  1UZP A;  1L5G B;  4X8U L;  2Y80 B;  3TH3 L;  1ATE A;  4RRW A;  1IQK L;  3M36 L;  3HO4 A;  2WZP P;  4BDX A;  2YGO A;  2VRS A;  3OLT A;  1IOX A;  1IQE L;  4LOR A;  3GIS X;  4ZXX L;  4Y71 B;  1GK5 A;  3NT1 A;  2P3F N;  3HS6 A;  2J95 B;  1LMJ A;  2G00 L;  2RA0 L;  4O02 B;  1FAK L;  4ZHA B;  1EZQ B;  3K9X A;  2OYU P;  2WYJ B;  1YUF A;  1G2L B;  2AYL A;  4Y76 B;  4CSY A;  2VVC K;  2JKH L;  2P94 L;  3NJP C;  4MMX B;  4D0E A;  2WFT A;  5JB8 E;  3LN1 A;  5IKT A;  1EPG A;  3TK6 B;  1IQF L;  1DX5 I;  3KCG L;  1XFE A;  1XDT R;  2WYG B;  2ADX A;  2WPM E;  2BZ6 L;  5COX A;  2CJI B;  2XC4 L;  4ISH L;  3R05 A;  1IQI L;  5CKM A;  5KN5 C;  5JVZ A;  1XKB A;  1DIY A;  3S6X A;  1FE2 A;  1JV2 B;  1CCV A;  4JYV L;  4BTT A;  2VVV L;  3GCX E;  4CUE A;  4Z6A L;  1CVU A;  5I46 L;  2J34 B;  2W86 A;  2BQW A;  2Y38 A;  1V1H A;  3FFG L;  3MQE A;  4RRX A;  5K0H B;  2D1J B;  4CUF A;  1LMM A;  4MMY B;  1WU1 B;  2P3U A;  2WPI E;  1KLO A;  4X8T L;  2PR3 B;  1UZK A;  2GD4 A;  1LPZ A;  3N8X A;  5IKV A;  2XBW L;  4JZE L;  2UWL B;  1PFX L;  4XL1 A;  1EGF A;  2RNL A;  2W2Q E;  1AUT L;  1COU A;  1IQH L;  1IQL L;  1KLJ L;  1NPE B;  2VJ3 A;  2EI8 B;  3HS5 A;  1IQG L;  4LMF A;  1PRH A;  4Y6D B;  2NPR A;  4RUT A;  3C9A C;  3KQD L;  1Z6E L;  1P9J A;  3KQE L;  3M37 L;  1KLI L;  3RR3 A;  3QMO A;  1EMN A;  2VH0 B;  2Y7X B;  2P16 L;  1FJS L;  5F1A A;  3V65 B;  1PGE A;  3SOB B;  1IQN L;  5CKQ A;  1DQB A;  2DDU A;  4COX A;  1M1X B;  3GCW E;  2P95 L;  2Y7Z B;  1HX2 A;  3LC5 B;  4GU4 A;  2WPL E;  2P3T A;  1I0U A;  1NT0 A;  2P93 L;  4OTY A;  2VWM K;  2PUQ L;  3V64 C;  1NFU B;  5JBB E;  3TZI A;  4ZXY L;  2WG4 B;  4BTI A;  2YGP A;  3CS7 L;  4NG9 L;  3NTG A;  4RRY A;  3POY A;  2P28 B;  2BSF A;  3KL6 B;  2VWO L;  1TLE A;  3BPS E;  4M10 A;  3HPT A;  3PGH A;  4FM5 A;  4MMZ B;  1G1S A;  3OLU A;  4XLW A;  1QIU A;  5IKR A;  1URK A;  1NFW B;  4M11 A;  4Y79 B;  2J4I B;  1YO8 A;  2BOH A;  1G2M B;  1HRE A;  1F7E A;  2WPJ E;  3IIT B;  1LPG A;  3ELA L;  4NA9 L;  5E8D A;  4GU3 A;  4YT7 L;  1C5M F;  3F1S B;  1HCG B;  2Y81 B;  1UZQ A;  3KRK A;  4YZU B;  3ZYI B;  1MQ6 L;  2P26 A;  3N8Y B;  2OYE P;  4JZD L;  2EI7 B;  1W8B L;  2VWL L;  4Y7A B;  2BOX A;  1APO A;  4JYU L;  2W2M E;  3P5B L;  2W2N E;  2XBX L;  1F7M A;  1WHE A;  2K2S B;  2Y5F L;  3BT1 A;  1UZJ A;  2B7D L;  2WPK E;  1F0S B;  4BTU A;  5JBC E;  3FCS B;  3Q7D A;  3CEN L;  1NZI A;  1YGC L;  4Y7B B;  2W3K B;  1K37 A;  1WHF A;  2Y5G L;  3ZYG A;  3U7U G;  3HS7 A;  2W26 B;  5JVY A;  2MGP A;  2Y82 B;  3LTG D;  1EPI A;  2BOU A;  2KB9 A;  2RHP A;  3LIW B;  1FF7 A;  1U67 A;  5L2Z L;  1CQE A;  1IGX A;  1Q4G A;  4G1M B;  3LAQ A;  2XBV L;  1JL9 A;  5CKN A;  1EPH A;  2BO2 A;  4BXS A;  3EGF A;  2MGR A;  4TGF A;  1JBU L;  1HT5 A;  4ZAE B;  5FDQ A;  1CVW L;  1EBV A;  1ADX A;  3HO5 A;  2H9E L;  1U8C B;  1CEJ A;  5IKQ A;  1W7X L;  3FBY A;  2EI6 B;  3LN0 A;  4YT6 L;  2BQ7 A;  3N8Z A;  1L3Y A;  4OTJ A;  3CFW A;  3QCW A;  4X8V L;  1CCF A;  4D90 A;  1SZB A;  4ISI L;  4O1Z A;  2J94 B;  1LPK A;  4XBM A;  1FFM A;  2FLG A;  1EPJ A;  4CUD A;  3N8Y A;  2TGF A;  5L30 L;  5CIS A;  1NFY B;  3KK6 A;  1V3X B;  3F6U L;  2P3F L;  2HOR A;  2W2P E;  1F0R B;  5L2Y L;  1B9W A;  2FZZ L;  2J38 B;  1HAE A;  1MOX C;  3KQC L;  1TPG A;  2WG3 C;  1IQJ L;  2VWN L;  3IJE B;  1IGZ A;  1V1I A;  2Y5H L;  5F19 A;  4RS0 A;  1HZ8 A;  5EGM B;  2XC0 L;  3LC3 B;  1HAF A;  3SOQ A;  1IP0 A;  2BMG A;  1BF9 A;  2W3I B;  3NTB A;  1IVO C;  1TOZ A;  2UWP B;  1A3P A;  2F9B L;  1IOE L;  4ZH8 B;  2FLR L;  2YGQ A;  3H5C B;  1K36 A;  6COX A;  1IJQ A;  2FLB L;  1Z6C A;  4A7I A;  2VVU L;  2XBY L;  1DVA L;  3TK5 B;  1IQM L;  3SW2 A;  5JBA E;  4NGA L;  1OB1 C;  4D0F A;  2WPH E;  1ATA A;  4JZF L;  1G1T A;  1FAX L;  3N8V A;  2H9E C;  5JW1 A;  1YUK B;  3N8W A;  1N7D A;  2WFX B;  1PXX A;  2JJL A;  1RFN B;  1DDX A;  1APQ A;  2J2U B;  1XKA L;  4BXW A;  2K2T A;  2M74 A;  1X7A L;  2XC5 L;  1KKE A;  2FD6 A;  1ZAQ A;  2BQ6 A;  4RRZ A;  1ATB A;  2I9A A;  2KNI A;  1LQD A;  1J9C L;  3DEM A;  5KIR A;  1HT8 A;  2PHB B;  1O5D L;  1KSN B;  2UWO B;  1HRF A;  4PH9 A;  3N8W B;  1HJ7 A;  1EAI C;  1G1Q A;  1LK9 A;  3QH0 A;  1EMO A;  2BT7 A;  1NFX B;  1PTH A;  3HO3 A;  3MDL A;  1ATD A;  2KV4 A;  5JB9 E;  3ASI A;  1CX2 A;  1YUG A;  1EQG A;  1N1I A;  3Q3K B;  1NQL B;  2W2O E;  1KIG L;  3CA7 A;  3LTF B;  4C16 A;  2MHP A;  3U73 A;  2BT8 A;  3TGF A;  3SOV A;  1P0S L;  1QFK L;  1G1R A; 
#chains in the Genus database with same CATH homology
 4Z0K B;  4E1G A;  3ENS A;  3TBD A;  2BOK L;  2I9B A;  2KL7 A;  4BDW A;  1FSB A;  4X8S L;  1MQ5 L;  3BT2 A;  1EQH A;  4AQT A;  2VH6 B;  4Z0L A;  2Q1J B;  3KQB L;  3ZYJ B;  4A94 C;  1UZP A;  1L5G B;  4X8U L;  2Y80 B;  3TH3 L;  1ATE A;  4RRW A;  1IQK L;  3M36 L;  3HO4 A;  2WZP P;  4BDX A;  2YGO A;  3OLT A;  1IOX A;  1IQE L;  4LOR A;  3GIS X;  4ZXX L;  4Y71 B;  1GK5 A;  3NT1 A;  2P3F N;  3HS6 A;  2J95 B;  1LMJ A;  2G00 L;  2RA0 L;  4O02 B;  1FAK L;  4ZHA B;  1EZQ B;  3K9X A;  2OYU P;  2WYJ B;  1YUF A;  1G2L B;  2AYL A;  4Y76 B;  4CSY A;  2VVC K;  2JKH L;  2P94 L;  3NJP C;  4MMX B;  4D0E A;  2WFT A;  5JB8 E;  3LN1 A;  5IKT A;  1EPG A;  3TK6 B;  1IQF L;  1DX5 I;  3KCG L;  1XFE A;  1XDT R;  2WYG B;  2ADX A;  2WPM E;  2BZ6 L;  5COX A;  2CJI B;  2XC4 L;  4ISH L;  3R05 A;  1IQI L;  5CKM A;  5KN5 C;  5JVZ A;  1XKB A;  1DIY A;  3S6X A;  1FE2 A;  1JV2 B;  1CCV A;  4JYV L;  4BTT A;  2VVV L;  3GCX E;  4CUE A;  4Z6A L;  1CVU A;  5I46 L;  2J34 B;  2W86 A;  2BQW A;  2Y38 A;  3FFG L;  3MQE A;  4RRX A;  5K0H B;  2D1J B;  4CUF A;  1LMM A;  4MMY B;  1WU1 B;  2P3U A;  2WPI E;  1KLO A;  4X8T L;  2PR3 B;  1UZK A;  2GD4 A;  1LPZ A;  3N8X A;  5IKV A;  2XBW L;  4JZE L;  2UWL B;  1PFX L;  4XL1 A;  1EGF A;  2RNL A;  2W2Q E;  1AUT L;  1COU A;  1IQH L;  1IQL L;  1KLJ L;  1NPE B;  2VJ3 A;  2EI8 B;  3HS5 A;  1IQG L;  4LMF A;  1PRH A;  4Y6D B;  2NPR A;  4RUT A;  3C9A C;  3KQD L;  1Z6E L;  1P9J A;  3KQE L;  3M37 L;  1KLI L;  3RR3 A;  3QMO A;  1EMN A;  2VH0 B;  2Y7X B;  2P16 L;  1FJS L;  5F1A A;  3V65 B;  1PGE A;  3SOB B;  1IQN L;  5CKQ A;  1DQB A;  2DDU A;  4COX A;  1M1X B;  3GCW E;  2P95 L;  2Y7Z B;  1HX2 A;  3LC5 B;  2WPL E;  2P3T A;  1I0U A;  1NT0 A;  2P93 L;  4OTY A;  2VWM K;  2PUQ L;  3V64 C;  1NFU B;  5JBB E;  3TZI A;  4ZXY L;  2WG4 B;  4BTI A;  2YGP A;  3CS7 L;  4NG9 L;  3NTG A;  4RRY A;  3POY A;  2P28 B;  3KL6 B;  2VWO L;  1TLE A;  3BPS E;  4M10 A;  3HPT A;  3PGH A;  4FM5 A;  4MMZ B;  1G1S A;  3OLU A;  4XLW A;  5IKR A;  1URK A;  1NFW B;  4M11 A;  4Y79 B;  2J4I B;  1YO8 A;  2BOH A;  1G2M B;  1HRE A;  1F7E A;  2WPJ E;  3IIT B;  1LPG A;  3ELA L;  4NA9 L;  5E8D A;  4YT7 L;  1C5M F;  3F1S B;  1HCG B;  2Y81 B;  1UZQ A;  3KRK A;  4YZU B;  3ZYI B;  1MQ6 L;  2P26 A;  3N8Y B;  2OYE P;  4JZD L;  2EI7 B;  1W8B L;  2VWL L;  4Y7A B;  2BOX A;  1APO A;  4JYU L;  2W2M E;  3P5B L;  2W2N E;  2XBX L;  1F7M A;  1WHE A;  2K2S B;  2Y5F L;  3BT1 A;  1UZJ A;  2B7D L;  2WPK E;  1F0S B;  4BTU A;  5JBC E;  3FCS B;  3Q7D A;  3CEN L;  1NZI A;  1YGC L;  4Y7B B;  2W3K B;  1K37 A;  1WHF A;  2Y5G L;  3ZYG A;  3U7U G;  3HS7 A;  2W26 B;  5JVY A;  2MGP A;  2Y82 B;  3LTG D;  1EPI A;  2BOU A;  2KB9 A;  2RHP A;  3LIW B;  1FF7 A;  1U67 A;  5L2Z L;  1CQE A;  1IGX A;  1Q4G A;  4G1M B;  3LAQ A;  2XBV L;  1JL9 A;  5CKN A;  1EPH A;  2BO2 A;  4BXS A;  3EGF A;  2MGR A;  4TGF A;  1JBU L;  1HT5 A;  4ZAE B;  5FDQ A;  1CVW L;  1EBV A;  1ADX A;  3HO5 A;  2H9E L;  1U8C B;  1CEJ A;  5IKQ A;  1W7X L;  3FBY A;  2EI6 B;  3LN0 A;  4YT6 L;  2BQ7 A;  3N8Z A;  1L3Y A;  4OTJ A;  3CFW A;  3QCW A;  4X8V L;  1CCF A;  4D90 A;  1SZB A;  4ISI L;  4O1Z A;  2J94 B;  1LPK A;  4XBM A;  1FFM A;  2FLG A;  1EPJ A;  4CUD A;  3N8Y A;  2TGF A;  5L30 L;  5CIS A;  1NFY B;  3KK6 A;  1V3X B;  3F6U L;  2P3F L;  2W2P E;  1F0R B;  5L2Y L;  1B9W A;  2FZZ L;  2J38 B;  1HAE A;  1MOX C;  3KQC L;  1TPG A;  2WG3 C;  1IQJ L;  2VWN L;  3IJE B;  1IGZ A;  2Y5H L;  5F19 A;  4RS0 A;  1HZ8 A;  5EGM B;  2XC0 L;  3LC3 B;  1HAF A;  3SOQ A;  1IP0 A;  2BMG A;  1BF9 A;  2W3I B;  3NTB A;  1IVO C;  1TOZ A;  2UWP B;  1A3P A;  2F9B L;  1IOE L;  4ZH8 B;  2FLR L;  2YGQ A;  3H5C B;  1K36 A;  6COX A;  1IJQ A;  2FLB L;  1Z6C A;  4A7I A;  2VVU L;  2XBY L;  1DVA L;  3TK5 B;  1IQM L;  3SW2 A;  5JBA E;  4NGA L;  1OB1 C;  4D0F A;  2WPH E;  1ATA A;  4JZF L;  1G1T A;  1FAX L;  3N8V A;  2H9E C;  5JW1 A;  1YUK B;  3N8W A;  1N7D A;  2WFX B;  1PXX A;  1RFN B;  1DDX A;  1APQ A;  2J2U B;  1XKA L;  4BXW A;  2K2T A;  2M74 A;  1X7A L;  2XC5 L;  2FD6 A;  1ZAQ A;  2BQ6 A;  4RRZ A;  1ATB A;  2I9A A;  2KNI A;  1LQD A;  1J9C L;  3DEM A;  5KIR A;  1HT8 A;  2PHB B;  1O5D L;  1KSN B;  2UWO B;  1HRF A;  4PH9 A;  3N8W B;  1HJ7 A;  1EAI C;  1G1Q A;  3QH0 A;  1EMO A;  1ATD A;  1NFX B;  1PTH A;  3HO3 A;  3MDL A;  2KV4 A;  5JB9 E;  3ASI A;  1CX2 A;  1YUG A;  1EQG A;  1N1I A;  3Q3K B;  1NQL B;  2W2O E;  1KIG L;  3CA7 A;  3LTF B;  4C16 A;  2MHP A;  3U73 A;  3TGF A;  3SOV A;  1P0S L;  1QFK L;  1G1R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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