3M37L

Factor xa in complex with the inhibitor 1-[2-(aminomethyl)phenyl]-n-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3-(trifluoromethyl)-1h-pyrazole-5-carboxamide (dpc602)
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
publication title Discovery of 1-(2-Aminomethylphenyl)-3-trifluoromethyl-N-[3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-1H-pyrazole-5-carboxyamide (DPC602), a Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor.
pubmed rcsb
molecule keywords Coagulation factor X
total genus 13
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2010-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3m37L00
2Y5HL 1L3YA 1IGZA 2W2QE 1HAFA 1GK5A 5CKNA 1IQJL 4JYUL 4RUTA 2Y82B 2BOUA 3LAQA 4D0FA 3N8VA 2W2NE 5CISA 1BF9A 5E8DA 1APQA 1PXXA 2BOKL 4X8VL 2BQ7A 2Y38A 2W2PE 2XC0L 2PHBB 1NFXB 3NT1A 2WPJE 2B7DL 2YGPA 3U73A 2J94B 1FF7A 4YT6L 4AQTA 3GCXE 1G2MB 3V65B 3HPTA 3F1SB 1CX2A 2TGFA 3F6UL 2UWOB 1IGXA 1UZKA 5CKQA 2EI6B 3KQCL 1EZQB 1LQDA 1IQFL 3LIWB 3SW2A 1Z6EL 1JV2B 2P3UA 1HCGB 1PFXL 3MQEA 2WPLE 1DDXA 1EPHA 5JW1A 1EPIA 1COUA 4TGFA 3NTBA 1UZPA 2PR3B 3CS7L 3KCGL 1QFKL 1Z6CA 3QCWA 1SZBA 4M10A 1CCVA 5L2ZL 3EGFA 4ISHL 4G1MB 1IQGL 4BXSA 1HJ7A 2FD6A 1IQIL 5L2YL 1PGEA 2F9BL 1MQ5L 4JZFL 2EI8B 4Z0LA 2BMGA 1W8BL 3GISX 5CKMA 3QH0A 1TPGA 2XBVL 3C9AC 2P26A 2NPRA 1V3XB 3V64C 1PRHA 3NJPC 4X8UL 3N8YA 5JBCE 1ATBA 2WYGB 4RRWA 2KB9A 1X7AL 2MGRA 2P3FN 1P0SL 4YZUB 1TLEA 2Y7ZB 4D90A 4BXWA 2YGOA 4OTJA 1IQNL 3GCWE 1IOXA 1Q4GA 3N8WB 4OTYA 4XBMA 4JYVL 2Q1JB 5JBBE 3QMOA 2BZ6L 4JZEL 4NG9L 1KLOA 1HREA 1APOA 1DIYA 1KIGL 1NPEB 1HRFA 2W86A 5JVZA 5L30L 1G1RA 3R05A 1HZ8A 1DX5I 1PTHA 2ADXA 2P3FL 5IKTA 3TGFA 1B9WA 4MMZB 1LPZA 3HO3A 3FBYA 3Q7DA 2W3IB 3IJEB 5I46L 3SOQA 4LMFA 3HS6A 2FLBL 4O02B 3KL6B 2Y5FL 4RS0A 1A3PA 2VJ3A 4Z0KB 1UZQA 2WPKE 5KN5C 2Y80B 1XDTR 1U67A 3KQEL 4MMXB 2VVCK 2Y7XB 2J2UB 3CENL 6COXA 4A7IA 1IQLL 1NT0A 2RA0L 1YUFA 1HT8A 4RRXA 1FFMA 1N1IA 1NFYB 1XFEA 2H9EL 2P95L 2FZZL 3ASIA 2FLRL 1HT5A 1K37A 2K2TA 3FFGL 1ATAA 1J9CL 4M11A 5JB9E 5IKRA 3TBDA 2Y81B 2WPIE 4ZHAB 5IKVA 1L5GB 2I9BA 1YGCL 3LC3B 1URKA 1EMNA 5F1AA 2P94L 1MQ6L 3N8XA 2W3KB 1EAIC 2M74A 4ISIL 4Y6DB 2BOXA 2RHPA 2WG3C 1IQKL 1IQEL 4Y7AB 3MDLA 3KRKA 4BDXA 2VVUL 1IQML 2RNLA 2OYUP 2J38B 1NFWB 3LN0A 1EQHA 4ZXXL 3BT1A 4ZXYL 1DVAL 4NGAL 2J34B 4ZAEB 1KLJL 3P5BL 1KSNB 1CCFA 4FM5A 2PUQL 1EMOA 1G2LB 3CFWA 3N8WA 3K9XA 1FAKL 1WHFA 3LC5B 5F19A 4Y71B 3KQDL 3LTGD 1WHEA 2BOHA 1I0UA 1K36A 2J4IB 4RRYA 2XC5L 5COXA 2DDUA 1FAXL 3LN1A 3ZYGA 3KK6A 5K0HB 1FSBA 3ENSA 3ZYIB 1W7XL 2CJIB 3M36L 2VWLL 3TH3L 1XKBA 3HS7A 4RRZA 1CQEA 1F0RB 3FCSB 3ELAL 3U7UG 1P9JA 1XKAL 1M1XB 1JBUL 2BO2A 1IP0A 1AUTL 1IQHL 2VWMK 2Y5GL 4PH9A 4NA9L 1IVOC 2VH0B 1FJSL 1HAEA 4YT7L 2G00L 2P16L 4Z6AL 1RFNB 2W26B 1YUGA 1IOEL 2GD4A 2WPME 2XC4L 2P3TA 1JL9A 3HS5A 5EGMB 4BDWA 4BTUA 3TZIA 2WG4B 3OLTA 1F7MA 2XBXL 1HX2A 2VH6B 1EQGA 3TK5B 1F7EA 1LPGA 3DEMA 1LPKA 2BQ6A 4CUFA 3IITB 4CUDA 1MOXC 3PGHA 3POYA 5JB8E 2WFXB 3H5CB 1NZIA 1DQBA 3RR3A 1G1QA 3KQBL 1ATEA 3LTFB 1FE2A 1EPJA 2P28B 2MHPA 1NQLB 2UWPB 1C5MF 1OB1C 5JBAE 2WYJB 2XBYL 1N7DA 1EBVA 1ZAQA 3OLUA 4D0EA 5JVYA 3HO5A 1CVWL 4Y76B 2VWOL 2W2ME 2J95B 1NFUB 1LMJA 1YUKB 2VVVL 4ZH8B 4BTTA 2XBWL 4C16A 2K2SB 4JZDL 3NTGA 4O1ZA 3BT2A 3HO4A 2I9AA 2VWNL 2W2OE 3SOBB 1ADXA 4XLWA 4X8SL 4X8TL 2D1JB 4CUEA 1U8CB 1G1SA 1G1TA 2UWLB 1IJQA 1WU1B 2KL7A 3Q3KB 3N8ZA 5KIRA 3TK6B 2WFTA 1ATDA 1EPGA 1EGFA 5FDQA 4Y7BB 5IKQA 3CA7A 3M37L 4BTIA 4COXA 2MGPA 1TOZA 3N8YB 2FLGA 4MMYB 3ZYJB 1CEJA 2OYEP 1KLIL 2P93L 2WPHE 4E1GA 2BQWA 4LORA 1F0SB 4Y79B 1UZJA 2AYLA 1YO8A 3BPSE 4CSYA 4XL1A 1CVUA 2JKHL 3SOVA 2EI7B 1O5DL 2KV4A
chains in the Genus database with same CATH superfamily
2Y5HL 1L3YA 1IGZA 2W2QE 1HAFA 1GK5A 5CKNA 1IQJL 3S6XA 4JYUL 4RUTA 2Y82B 2BOUA 3LAQA 4D0FA 3N8VA 2W2NE 5CISA 1BF9A 5E8DA 1APQA 1PXXA 2BOKL 4X8VL 2BQ7A 2Y38A 2W2PE 2XC0L 2PHBB 1NFXB 3NT1A 2WPJE 2B7DL 2YGPA 3U73A 2J94B 1FF7A 4YT6L 4AQTA 3GCXE 1G2MB 3V65B 3HPTA 3F1SB 2BSFA 1CX2A 2TGFA 3F6UL 2UWOB 1IGXA 1UZKA 5CKQA 2EI6B 3KQCL 1EZQB 1LQDA 1IQFL 3LIWB 3SW2A 1Z6EL 1JV2B 2P3UA 1HCGB 1PFXL 3MQEA 2WPLE 1DDXA 1EPHA 5JW1A 1EPIA 1COUA 4TGFA 3NTBA 1UZPA 2PR3B 3CS7L 3KCGL 1QFKL 1Z6CA 3QCWA 1SZBA 4M10A 1CCVA 5L2ZL 3EGFA 4ISHL 4G1MB 1IQGL 4BXSA 1HJ7A 2FD6A 1IQIL 5L2YL 1PGEA 2F9BL 1MQ5L 4JZFL 2EI8B 4Z0LA 1V1HA 2BMGA 1W8BL 3GISX 5CKMA 3QH0A 1TPGA 2XBVL 3C9AC 2P26A 2NPRA 1V3XB 3V64C 1PRHA 3NJPC 4X8UL 3N8YA 5JBCE 1ATBA 2WYGB 4RRWA 2KB9A 1X7AL 2MGRA 2P3FN 1P0SL 4YZUB 1TLEA 2HORA 2Y7ZB 4D90A 4BXWA 2YGOA 4OTJA 1IQNL 3GCWE 1IOXA 1Q4GA 3N8WB 4OTYA 4XBMA 4JYVL 2Q1JB 5JBBE 3QMOA 2BZ6L 4JZEL 4NG9L 1KLOA 1HREA 1APOA 1DIYA 1KIGL 1NPEB 2KNIA 1HRFA 2W86A 5JVZA 5L30L 1G1RA 3R05A 1HZ8A 1DX5I 1PTHA 2ADXA 2P3FL 5IKTA 3TGFA 1B9WA 4MMZB 1LPZA 3HO3A 3FBYA 3Q7DA 2W3IB 3IJEB 5I46L 3SOQA 4LMFA 3HS6A 2FLBL 4O02B 3KL6B 2Y5FL 4RS0A 1A3PA 2VJ3A 4Z0KB 1UZQA 2WPKE 5KN5C 2Y80B 1XDTR 1U67A 3KQEL 4MMXB 2VVCK 2Y7XB 2J2UB 3CENL 6COXA 4A7IA 1IQLL 1NT0A 2RA0L 1YUFA 1HT8A 4GU4A 4RRXA 1FFMA 1N1IA 1NFYB 1XFEA 1QIUA 2H9EL 2P95L 2FZZL 3ASIA 2FLRL 1HT5A 1K37A 2K2TA 3FFGL 1ATAA 1J9CL 4GU3A 4M11A 5JB9E 5IKRA 3TBDA 2Y81B 2WPIE 4ZHAB 5IKVA 1L5GB 2I9BA 1YGCL 3LC3B 1URKA 1EMNA 5F1AA 2P94L 1MQ6L 3N8XA 2W3KB 1EAIC 2M74A 4ISIL 4Y6DB 2BOXA 2RHPA 2WG3C 1IQKL 1IQEL 4Y7AB 3MDLA 3KRKA 4BDXA 2VVUL 1IQML 2RNLA 2OYUP 2J38B 1NFWB 3LN0A 1EQHA 4ZXXL 3BT1A 4ZXYL 1DVAL 4NGAL 2J34B 4ZAEB 1KLJL 3P5BL 1KSNB 1CCFA 4FM5A 2PUQL 1EMOA 1G2LB 3CFWA 3N8WA 3K9XA 1FAKL 1WHFA 3LC5B 5F19A 4Y71B 3KQDL 3LTGD 1WHEA 2BOHA 1I0UA 1K36A 2J4IB 4RRYA 2XC5L 5COXA 2DDUA 1FAXL 3LN1A 3ZYGA 3KK6A 5K0HB 1FSBA 3ENSA 3ZYIB 1W7XL 2CJIB 3M36L 2VWLL 3TH3L 1XKBA 3HS7A 4RRZA 1CQEA 1F0RB 3FCSB 3ELAL 2YGQA 3U7UG 1P9JA 1XKAL 1M1XB 1JBUL 2BO2A 1IP0A 2BT8A 1AUTL 1IQHL 2VWMK 2Y5GL 4PH9A 4NA9L 1IVOC 2VH0B 1FJSL 1HAEA 4YT7L 2G00L 2P16L 4Z6AL 1RFNB 2W26B 2WZPP 1YUGA 1IOEL 2GD4A 2HOXA 2WPME 2XC4L 2P3TA 1JL9A 3HS5A 5EGMB 4BDWA 4BTUA 3TZIA 2WG4B 3OLTA 1F7MA 2XBXL 1HX2A 2VH6B 1EQGA 3TK5B 1F7EA 1LPGA 3DEMA 1LPKA 2BQ6A 4CUFA 3IITB 4CUDA 1MOXC 3PGHA 3POYA 5JB8E 2WFXB 3H5CB 1NZIA 1DQBA 3RR3A 1G1QA 3KQBL 1ATEA 3LTFB 1FE2A 1EPJA 2P28B 2MHPA 1NQLB 2UWPB 1C5MF 1OB1C 5JBAE 2WYJB 2XBYL 1N7DA 1KKEA 1EBVA 1V1IA 1ZAQA 3OLUA 4D0EA 5JVYA 2JJLA 3HO5A 1CVWL 4Y76B 2VWOL 2W2ME 2J95B 1NFUB 2H9EC 1LMJA 1YUKB 2VVVL 4ZH8B 4BTTA 2XBWL 4C16A 2K2SB 4JZDL 3NTGA 4O1ZA 3BT2A 3HO4A 2I9AA 2VWNL 2W2OE 3SOBB 1ADXA 4XLWA 4X8SL 4X8TL 2D1JB 4CUEA 1U8CB 1G1SA 2VRSA 1G1TA 2UWLB 1IJQA 1WU1B 2KL7A 3Q3KB 3N8ZA 5KIRA 3TK6B 2WFTA 1ATDA 1EPGA 1EGFA 5FDQA 4Y7BB 5IKQA 3CA7A 3M37L 4BTIA 4COXA 2MGPA 1TOZA 3N8YB 2FLGA 4MMYB 3ZYJB 1CEJA 2OYEP 1KLIL 2P93L 2WPHE 4E1GA 2BQWA 1LMMA 4LORA 1F0SB 4Y79B 1UZJA 2AYLA 1YO8A 3BPSE 4CSYA 4XL1A 1LK9A 1CVUA 4A94C 2BT7A 2JKHL 3SOVA 2EI7B 1O5DL 2KV4A
chains in the Genus database with same CATH topology
2Y5HL 1L3YA 1IGZA 2W2QE 1HAFA 1GK5A 5CKNA 1IQJL 3S6XA 4JYUL 4RUTA 2Y82B 2BOUA 3LAQA 4D0FA 3N8VA 2W2NE 5CISA 1BF9A 5E8DA 1APQA 1PXXA 2BOKL 4X8VL 2BQ7A 2Y38A 2W2PE 2XC0L 2PHBB 1NFXB 3NT1A 2WPJE 2B7DL 2YGPA 3U73A 2J94B 1FF7A 4YT6L 4AQTA 3GCXE 1G2MB 3V65B 3HPTA 3F1SB 1CX2A 2TGFA 3F6UL 2UWOB 1IGXA 1UZKA 5CKQA 2EI6B 3KQCL 1EZQB 1LQDA 1IQFL 3LIWB 3SW2A 1Z6EL 1JV2B 2P3UA 1HCGB 1PFXL 3MQEA 2WPLE 1DDXA 1EPHA 5JW1A 1EPIA 1COUA 4TGFA 3NTBA 1UZPA 2PR3B 3CS7L 3KCGL 1QFKL 1Z6CA 3QCWA 1SZBA 4M10A 1CCVA 5L2ZL 3EGFA 4ISHL 4G1MB 1IQGL 4BXSA 1HJ7A 2FD6A 1IQIL 5L2YL 1PGEA 2F9BL 1MQ5L 4JZFL 2EI8B 4Z0LA 2BMGA 1W8BL 3GISX 5CKMA 3QH0A 1TPGA 2XBVL 3C9AC 2P26A 2NPRA 1V3XB 3V64C 1PRHA 3NJPC 4X8UL 3N8YA 5JBCE 1ATBA 2WYGB 4RRWA 2KB9A 1X7AL 2MGRA 2P3FN 1P0SL 4YZUB 1TLEA 2Y7ZB 4D90A 4BXWA 2YGOA 4OTJA 1IQNL 3GCWE 1IOXA 1Q4GA 3N8WB 4OTYA 4XBMA 4JYVL 2Q1JB 5JBBE 3QMOA 2BZ6L 4JZEL 4NG9L 1KLOA 1HREA 1APOA 1DIYA 1KIGL 1NPEB 2KNIA 1HRFA 2W86A 5JVZA 5L30L 1G1RA 3R05A 1HZ8A 1DX5I 1PTHA 2ADXA 2P3FL 5IKTA 3TGFA 1B9WA 4MMZB 1LPZA 3HO3A 3FBYA 3Q7DA 2W3IB 3IJEB 5I46L 3SOQA 4LMFA 3HS6A 2FLBL 4O02B 3KL6B 2Y5FL 4RS0A 1A3PA 2VJ3A 4Z0KB 1UZQA 2WPKE 5KN5C 2Y80B 1XDTR 1U67A 3KQEL 4MMXB 2VVCK 2Y7XB 2J2UB 3CENL 6COXA 4A7IA 1IQLL 1NT0A 2RA0L 1YUFA 1HT8A 4RRXA 1FFMA 1N1IA 1NFYB 1XFEA 2H9EL 2P95L 2FZZL 3ASIA 2FLRL 1HT5A 1K37A 2K2TA 3FFGL 1ATAA 1J9CL 4M11A 5JB9E 5IKRA 3TBDA 2Y81B 2WPIE 4ZHAB 5IKVA 1L5GB 2I9BA 1YGCL 3LC3B 1URKA 1EMNA 5F1AA 2P94L 1MQ6L 3N8XA 2W3KB 1EAIC 2M74A 4ISIL 4Y6DB 2BOXA 2RHPA 2WG3C 1IQKL 1IQEL 4Y7AB 3MDLA 3KRKA 4BDXA 2VVUL 1IQML 2RNLA 2OYUP 2J38B 1NFWB 3LN0A 1EQHA 4ZXXL 3BT1A 4ZXYL 1DVAL 4NGAL 2J34B 4ZAEB 1KLJL 3P5BL 1KSNB 1CCFA 4FM5A 2PUQL 1EMOA 1G2LB 3CFWA 3N8WA 3K9XA 1FAKL 1WHFA 3LC5B 5F19A 4Y71B 3KQDL 3LTGD 1WHEA 2BOHA 1I0UA 1K36A 2J4IB 4RRYA 2XC5L 5COXA 2DDUA 1FAXL 3LN1A 3ZYGA 3KK6A 5K0HB 1FSBA 3ENSA 3ZYIB 1W7XL 2CJIB 3M36L 2VWLL 3TH3L 1XKBA 3HS7A 4RRZA 1CQEA 1F0RB 3FCSB 3ELAL 2YGQA 3U7UG 1P9JA 1XKAL 1M1XB 1JBUL 2BO2A 1IP0A 1AUTL 1IQHL 2VWMK 2Y5GL 4PH9A 4NA9L 1IVOC 2VH0B 1FJSL 1HAEA 4YT7L 2G00L 2P16L 4Z6AL 1RFNB 2W26B 2WZPP 1YUGA 1IOEL 2GD4A 2WPME 2XC4L 2P3TA 1JL9A 3HS5A 5EGMB 4BDWA 4BTUA 3TZIA 2WG4B 3OLTA 1F7MA 2XBXL 1HX2A 2VH6B 1EQGA 3TK5B 1F7EA 1LPGA 3DEMA 1LPKA 2BQ6A 4CUFA 3IITB 4CUDA 1MOXC 3PGHA 3POYA 5JB8E 2WFXB 3H5CB 1NZIA 1DQBA 3RR3A 1G1QA 3KQBL 1ATEA 3LTFB 1FE2A 1EPJA 2P28B 2MHPA 1NQLB 2UWPB 1C5MF 1OB1C 5JBAE 2WYJB 2XBYL 1N7DA 1EBVA 1ZAQA 3OLUA 4D0EA 5JVYA 3HO5A 1CVWL 4Y76B 2VWOL 2W2ME 2J95B 1NFUB 2H9EC 1LMJA 1YUKB 2VVVL 4ZH8B 4BTTA 2XBWL 4C16A 2K2SB 4JZDL 3NTGA 4O1ZA 3BT2A 3HO4A 2I9AA 2VWNL 2W2OE 3SOBB 1ADXA 4XLWA 4X8SL 4X8TL 2D1JB 4CUEA 1U8CB 1G1SA 1G1TA 2UWLB 1IJQA 1WU1B 2KL7A 3Q3KB 3N8ZA 5KIRA 3TK6B 2WFTA 1ATDA 1EPGA 1EGFA 5FDQA 4Y7BB 5IKQA 3CA7A 3M37L 4BTIA 4COXA 2MGPA 1TOZA 3N8YB 2FLGA 4MMYB 3ZYJB 1CEJA 2OYEP 1KLIL 2P93L 2WPHE 4E1GA 2BQWA 1LMMA 4LORA 1F0SB 4Y79B 1UZJA 2AYLA 1YO8A 3BPSE 4CSYA 4XL1A 1CVUA 4A94C 2JKHL 3SOVA 2EI7B 1O5DL 2KV4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y5H L;  1L3Y A;  1IGZ A;  2W2Q E;  1HAF A;  1GK5 A;  5CKN A;  1IQJ L;  4JYU L;  4RUT A;  2Y82 B;  2BOU A;  3LAQ A;  4D0F A;  3N8V A;  2W2N E;  5CIS A;  1BF9 A;  5E8D A;  1APQ A;  1PXX A;  2BOK L;  4X8V L;  2BQ7 A;  2Y38 A;  2W2P E;  2XC0 L;  2PHB B;  1NFX B;  3NT1 A;  2WPJ E;  2B7D L;  2YGP A;  3U73 A;  2J94 B;  1FF7 A;  4YT6 L;  4AQT A;  3GCX E;  1G2M B;  3V65 B;  3HPT A;  3F1S B;  1CX2 A;  2TGF A;  3F6U L;  2UWO B;  1IGX A;  1UZK A;  5CKQ A;  2EI6 B;  3KQC L;  1EZQ B;  1LQD A;  1IQF L;  3LIW B;  3SW2 A;  1Z6E L;  1JV2 B;  2P3U A;  1HCG B;  1PFX L;  3MQE A;  2WPL E;  1DDX A;  1EPH A;  5JW1 A;  1EPI A;  1COU A;  4TGF A;  3NTB A;  1UZP A;  2PR3 B;  3CS7 L;  3KCG L;  1QFK L;  1Z6C A;  3QCW A;  1SZB A;  4M10 A;  1CCV A;  5L2Z L;  3EGF A;  4ISH L;  4G1M B;  1IQG L;  4BXS A;  1HJ7 A;  2FD6 A;  1IQI L;  5L2Y L;  1PGE A;  2F9B L;  1MQ5 L;  4JZF L;  2EI8 B;  4Z0L A;  2BMG A;  1W8B L;  3GIS X;  5CKM A;  3QH0 A;  1TPG A;  2XBV L;  3C9A C;  2P26 A;  2NPR A;  1V3X B;  3V64 C;  1PRH A;  3NJP C;  4X8U L;  3N8Y A;  5JBC E;  1ATB A;  2WYG B;  4RRW A;  2KB9 A;  1X7A L;  2MGR A;  2P3F N;  1P0S L;  4YZU B;  1TLE A;  2Y7Z B;  4D90 A;  4BXW A;  2YGO A;  4OTJ A;  1IQN L;  3GCW E;  1IOX A;  1Q4G A;  3N8W B;  4OTY A;  4XBM A;  4JYV L;  2Q1J B;  5JBB E;  3QMO A;  2BZ6 L;  4JZE L;  4NG9 L;  1KLO A;  1HRE A;  1APO A;  1DIY A;  1KIG L;  1NPE B;  1HRF A;  2W86 A;  5JVZ A;  5L30 L;  1G1R A;  3R05 A;  1HZ8 A;  1DX5 I;  1PTH A;  2ADX A;  2P3F L;  5IKT A;  3TGF A;  1B9W A;  4MMZ B;  1LPZ A;  3HO3 A;  3FBY A;  3Q7D A;  2W3I B;  3IJE B;  5I46 L;  3SOQ A;  4LMF A;  3HS6 A;  2FLB L;  4O02 B;  3KL6 B;  2Y5F L;  4RS0 A;  1A3P A;  2VJ3 A;  4Z0K B;  1UZQ A;  2WPK E;  5KN5 C;  2Y80 B;  1XDT R;  1U67 A;  3KQE L;  4MMX B;  2VVC K;  2Y7X B;  2J2U B;  3CEN L;  6COX A;  4A7I A;  1IQL L;  1NT0 A;  2RA0 L;  1YUF A;  1HT8 A;  4RRX A;  1FFM A;  1N1I A;  1NFY B;  1XFE A;  2H9E L;  2P95 L;  2FZZ L;  3ASI A;  2FLR L;  1HT5 A;  1K37 A;  2K2T A;  3FFG L;  1ATA A;  1J9C L;  4M11 A;  5JB9 E;  5IKR A;  3TBD A;  2Y81 B;  2WPI E;  4ZHA B;  5IKV A;  1L5G B;  2I9B A;  1YGC L;  3LC3 B;  1URK A;  1EMN A;  5F1A A;  2P94 L;  1MQ6 L;  3N8X A;  2W3K B;  1EAI C;  2M74 A;  4ISI L;  4Y6D B;  2BOX A;  2RHP A;  2WG3 C;  1IQK L;  1IQE L;  4Y7A B;  3MDL A;  3KRK A;  4BDX A;  2VVU L;  1IQM L;  2RNL A;  2OYU P;  2J38 B;  1NFW B;  3LN0 A;  1EQH A;  4ZXX L;  3BT1 A;  4ZXY L;  1DVA L;  4NGA L;  2J34 B;  4ZAE B;  1KLJ L;  3P5B L;  1KSN B;  1CCF A;  4FM5 A;  2PUQ L;  1EMO A;  1G2L B;  3CFW A;  3N8W A;  3K9X A;  1FAK L;  1WHF A;  3LC5 B;  5F19 A;  4Y71 B;  3KQD L;  3LTG D;  1WHE A;  2BOH A;  1I0U A;  1K36 A;  2J4I B;  4RRY A;  2XC5 L;  5COX A;  2DDU A;  1FAX L;  3LN1 A;  3ZYG A;  3KK6 A;  5K0H B;  1FSB A;  3ENS A;  3ZYI B;  1W7X L;  2CJI B;  3M36 L;  2VWL L;  3TH3 L;  1XKB A;  3HS7 A;  4RRZ A;  1CQE A;  1F0R B;  3FCS B;  3ELA L;  3U7U G;  1P9J A;  1XKA L;  1M1X B;  1JBU L;  2BO2 A;  1IP0 A;  1AUT L;  1IQH L;  2VWM K;  2Y5G L;  4PH9 A;  4NA9 L;  1IVO C;  2VH0 B;  1FJS L;  1HAE A;  4YT7 L;  2G00 L;  2P16 L;  4Z6A L;  1RFN B;  2W26 B;  1YUG A;  1IOE L;  2GD4 A;  2WPM E;  2XC4 L;  2P3T A;  1JL9 A;  3HS5 A;  5EGM B;  4BDW A;  4BTU A;  3TZI A;  2WG4 B;  3OLT A;  1F7M A;  2XBX L;  1HX2 A;  2VH6 B;  1EQG A;  3TK5 B;  1F7E A;  1LPG A;  3DEM A;  1LPK A;  2BQ6 A;  4CUF A;  3IIT B;  4CUD A;  1MOX C;  3PGH A;  3POY A;  5JB8 E;  2WFX B;  3H5C B;  1NZI A;  1DQB A;  3RR3 A;  1G1Q A;  3KQB L;  1ATE A;  3LTF B;  1FE2 A;  1EPJ A;  2P28 B;  2MHP A;  1NQL B;  2UWP B;  1C5M F;  1OB1 C;  5JBA E;  2WYJ B;  2XBY L;  1N7D A;  1EBV A;  1ZAQ A;  3OLU A;  4D0E A;  5JVY A;  3HO5 A;  1CVW L;  4Y76 B;  2VWO L;  2W2M E;  2J95 B;  1NFU B;  1LMJ A;  1YUK B;  2VVV L;  4ZH8 B;  4BTT A;  2XBW L;  4C16 A;  2K2S B;  4JZD L;  3NTG A;  4O1Z A;  3BT2 A;  3HO4 A;  2I9A A;  2VWN L;  2W2O E;  3SOB B;  1ADX A;  4XLW A;  4X8S L;  4X8T L;  2D1J B;  4CUE A;  1U8C B;  1G1S A;  1G1T A;  2UWL B;  1IJQ A;  1WU1 B;  2KL7 A;  3Q3K B;  3N8Z A;  5KIR A;  3TK6 B;  2WFT A;  1ATD A;  1EPG A;  1EGF A;  5FDQ A;  4Y7B B;  5IKQ A;  3CA7 A;  3M37 L;  4BTI A;  4COX A;  2MGP A;  1TOZ A;  3N8Y B;  2FLG A;  4MMY B;  3ZYJ B;  1CEJ A;  2OYE P;  1KLI L;  2P93 L;  2WPH E;  4E1G A;  2BQW A;  4LOR A;  1F0S B;  4Y79 B;  1UZJ A;  2AYL A;  1YO8 A;  3BPS E;  4CSY A;  4XL1 A;  1CVU A;  2JKH L;  3SOV A;  2EI7 B;  1O5D L;  2KV4 A; 
#chains in the Genus database with same CATH topology
 2Y5H L;  1L3Y A;  1IGZ A;  2W2Q E;  1HAF A;  1GK5 A;  5CKN A;  1IQJ L;  3S6X A;  4JYU L;  4RUT A;  2Y82 B;  2BOU A;  3LAQ A;  4D0F A;  3N8V A;  2W2N E;  5CIS A;  1BF9 A;  5E8D A;  1APQ A;  1PXX A;  2BOK L;  4X8V L;  2BQ7 A;  2Y38 A;  2W2P E;  2XC0 L;  2PHB B;  1NFX B;  3NT1 A;  2WPJ E;  2B7D L;  2YGP A;  3U73 A;  2J94 B;  1FF7 A;  4YT6 L;  4AQT A;  3GCX E;  1G2M B;  3V65 B;  3HPT A;  3F1S B;  2BSF A;  1CX2 A;  2TGF A;  3F6U L;  2UWO B;  1IGX A;  1UZK A;  5CKQ A;  2EI6 B;  3KQC L;  1EZQ B;  1LQD A;  1IQF L;  3LIW B;  3SW2 A;  1Z6E L;  1JV2 B;  2P3U A;  1HCG B;  1PFX L;  3MQE A;  2WPL E;  1DDX A;  1EPH A;  5JW1 A;  1EPI A;  1COU A;  4TGF A;  3NTB A;  1UZP A;  2PR3 B;  3CS7 L;  3KCG L;  1QFK L;  1Z6C A;  3QCW A;  1SZB A;  4M10 A;  1CCV A;  5L2Z L;  3EGF A;  4ISH L;  4G1M B;  1IQG L;  4BXS A;  1HJ7 A;  2FD6 A;  1IQI L;  5L2Y L;  1PGE A;  2F9B L;  1MQ5 L;  4JZF L;  2EI8 B;  4Z0L A;  1V1H A;  2BMG A;  1W8B L;  3GIS X;  5CKM A;  3QH0 A;  1TPG A;  2XBV L;  3C9A C;  2P26 A;  2NPR A;  1V3X B;  3V64 C;  1PRH A;  3NJP C;  4X8U L;  3N8Y A;  5JBC E;  1ATB A;  2WYG B;  4RRW A;  2KB9 A;  1X7A L;  2MGR A;  2P3F N;  1P0S L;  4YZU B;  1TLE A;  2HOR A;  2Y7Z B;  4D90 A;  4BXW A;  2YGO A;  4OTJ A;  1IQN L;  3GCW E;  1IOX A;  1Q4G A;  3N8W B;  4OTY A;  4XBM A;  4JYV L;  2Q1J B;  5JBB E;  3QMO A;  2BZ6 L;  4JZE L;  4NG9 L;  1KLO A;  1HRE A;  1APO A;  1DIY A;  1KIG L;  1NPE B;  2KNI A;  1HRF A;  2W86 A;  5JVZ A;  5L30 L;  1G1R A;  3R05 A;  1HZ8 A;  1DX5 I;  1PTH A;  2ADX A;  2P3F L;  5IKT A;  3TGF A;  1B9W A;  4MMZ B;  1LPZ A;  3HO3 A;  3FBY A;  3Q7D A;  2W3I B;  3IJE B;  5I46 L;  3SOQ A;  4LMF A;  3HS6 A;  2FLB L;  4O02 B;  3KL6 B;  2Y5F L;  4RS0 A;  1A3P A;  2VJ3 A;  4Z0K B;  1UZQ A;  2WPK E;  5KN5 C;  2Y80 B;  1XDT R;  1U67 A;  3KQE L;  4MMX B;  2VVC K;  2Y7X B;  2J2U B;  3CEN L;  6COX A;  4A7I A;  1IQL L;  1NT0 A;  2RA0 L;  1YUF A;  1HT8 A;  4GU4 A;  4RRX A;  1FFM A;  1N1I A;  1NFY B;  1XFE A;  1QIU A;  2H9E L;  2P95 L;  2FZZ L;  3ASI A;  2FLR L;  1HT5 A;  1K37 A;  2K2T A;  3FFG L;  1ATA A;  1J9C L;  4GU3 A;  4M11 A;  5JB9 E;  5IKR A;  3TBD A;  2Y81 B;  2WPI E;  4ZHA B;  5IKV A;  1L5G B;  2I9B A;  1YGC L;  3LC3 B;  1URK A;  1EMN A;  5F1A A;  2P94 L;  1MQ6 L;  3N8X A;  2W3K B;  1EAI C;  2M74 A;  4ISI L;  4Y6D B;  2BOX A;  2RHP A;  2WG3 C;  1IQK L;  1IQE L;  4Y7A B;  3MDL A;  3KRK A;  4BDX A;  2VVU L;  1IQM L;  2RNL A;  2OYU P;  2J38 B;  1NFW B;  3LN0 A;  1EQH A;  4ZXX L;  3BT1 A;  4ZXY L;  1DVA L;  4NGA L;  2J34 B;  4ZAE B;  1KLJ L;  3P5B L;  1KSN B;  1CCF A;  4FM5 A;  2PUQ L;  1EMO A;  1G2L B;  3CFW A;  3N8W A;  3K9X A;  1FAK L;  1WHF A;  3LC5 B;  5F19 A;  4Y71 B;  3KQD L;  3LTG D;  1WHE A;  2BOH A;  1I0U A;  1K36 A;  2J4I B;  4RRY A;  2XC5 L;  5COX A;  2DDU A;  1FAX L;  3LN1 A;  3ZYG A;  3KK6 A;  5K0H B;  1FSB A;  3ENS A;  3ZYI B;  1W7X L;  2CJI B;  3M36 L;  2VWL L;  3TH3 L;  1XKB A;  3HS7 A;  4RRZ A;  1CQE A;  1F0R B;  3FCS B;  3ELA L;  2YGQ A;  3U7U G;  1P9J A;  1XKA L;  1M1X B;  1JBU L;  2BO2 A;  1IP0 A;  2BT8 A;  1AUT L;  1IQH L;  2VWM K;  2Y5G L;  4PH9 A;  4NA9 L;  1IVO C;  2VH0 B;  1FJS L;  1HAE A;  4YT7 L;  2G00 L;  2P16 L;  4Z6A L;  1RFN B;  2W26 B;  2WZP P;  1YUG A;  1IOE L;  2GD4 A;  2HOX A;  2WPM E;  2XC4 L;  2P3T A;  1JL9 A;  3HS5 A;  5EGM B;  4BDW A;  4BTU A;  3TZI A;  2WG4 B;  3OLT A;  1F7M A;  2XBX L;  1HX2 A;  2VH6 B;  1EQG A;  3TK5 B;  1F7E A;  1LPG A;  3DEM A;  1LPK A;  2BQ6 A;  4CUF A;  3IIT B;  4CUD A;  1MOX C;  3PGH A;  3POY A;  5JB8 E;  2WFX B;  3H5C B;  1NZI A;  1DQB A;  3RR3 A;  1G1Q A;  3KQB L;  1ATE A;  3LTF B;  1FE2 A;  1EPJ A;  2P28 B;  2MHP A;  1NQL B;  2UWP B;  1C5M F;  1OB1 C;  5JBA E;  2WYJ B;  2XBY L;  1N7D A;  1KKE A;  1EBV A;  1V1I A;  1ZAQ A;  3OLU A;  4D0E A;  5JVY A;  2JJL A;  3HO5 A;  1CVW L;  4Y76 B;  2VWO L;  2W2M E;  2J95 B;  1NFU B;  2H9E C;  1LMJ A;  1YUK B;  2VVV L;  4ZH8 B;  4BTT A;  2XBW L;  4C16 A;  2K2S B;  4JZD L;  3NTG A;  4O1Z A;  3BT2 A;  3HO4 A;  2I9A A;  2VWN L;  2W2O E;  3SOB B;  1ADX A;  4XLW A;  4X8S L;  4X8T L;  2D1J B;  4CUE A;  1U8C B;  1G1S A;  2VRS A;  1G1T A;  2UWL B;  1IJQ A;  1WU1 B;  2KL7 A;  3Q3K B;  3N8Z A;  5KIR A;  3TK6 B;  2WFT A;  1ATD A;  1EPG A;  1EGF A;  5FDQ A;  4Y7B B;  5IKQ A;  3CA7 A;  3M37 L;  4BTI A;  4COX A;  2MGP A;  1TOZ A;  3N8Y B;  2FLG A;  4MMY B;  3ZYJ B;  1CEJ A;  2OYE P;  1KLI L;  2P93 L;  2WPH E;  4E1G A;  2BQW A;  1LMM A;  4LOR A;  1F0S B;  4Y79 B;  1UZJ A;  2AYL A;  1YO8 A;  3BPS E;  4CSY A;  4XL1 A;  1LK9 A;  1CVU A;  4A94 C;  2BT7 A;  2JKH L;  3SOV A;  2EI7 B;  1O5D L;  2KV4 A; 
#chains in the Genus database with same CATH homology
 2Y5H L;  1L3Y A;  1IGZ A;  2W2Q E;  1HAF A;  1GK5 A;  5CKN A;  1IQJ L;  3S6X A;  4JYU L;  4RUT A;  2Y82 B;  2BOU A;  3LAQ A;  4D0F A;  3N8V A;  2W2N E;  5CIS A;  1BF9 A;  5E8D A;  1APQ A;  1PXX A;  2BOK L;  4X8V L;  2BQ7 A;  2Y38 A;  2W2P E;  2XC0 L;  2PHB B;  1NFX B;  3NT1 A;  2WPJ E;  2B7D L;  2YGP A;  3U73 A;  2J94 B;  1FF7 A;  4YT6 L;  4AQT A;  3GCX E;  1G2M B;  3V65 B;  3HPT A;  3F1S B;  1CX2 A;  2TGF A;  3F6U L;  2UWO B;  1IGX A;  1UZK A;  5CKQ A;  2EI6 B;  3KQC L;  1EZQ B;  1LQD A;  1IQF L;  3LIW B;  3SW2 A;  1Z6E L;  1JV2 B;  2P3U A;  1HCG B;  1PFX L;  3MQE A;  2WPL E;  1DDX A;  1EPH A;  5JW1 A;  1EPI A;  1COU A;  4TGF A;  3NTB A;  1UZP A;  2PR3 B;  3CS7 L;  3KCG L;  1QFK L;  1Z6C A;  3QCW A;  1SZB A;  4M10 A;  1CCV A;  5L2Z L;  3EGF A;  4ISH L;  4G1M B;  1IQG L;  4BXS A;  1HJ7 A;  2FD6 A;  1IQI L;  5L2Y L;  1PGE A;  2F9B L;  1MQ5 L;  4JZF L;  2EI8 B;  4Z0L A;  2BMG A;  1W8B L;  3GIS X;  5CKM A;  3QH0 A;  1TPG A;  2XBV L;  3C9A C;  2P26 A;  2NPR A;  1V3X B;  3V64 C;  1PRH A;  3NJP C;  4X8U L;  3N8Y A;  5JBC E;  1ATB A;  2WYG B;  4RRW A;  2KB9 A;  1X7A L;  2MGR A;  2P3F N;  1P0S L;  4YZU B;  1TLE A;  2Y7Z B;  4D90 A;  4BXW A;  2YGO A;  4OTJ A;  1IQN L;  3GCW E;  1IOX A;  1Q4G A;  3N8W B;  4OTY A;  4XBM A;  4JYV L;  2Q1J B;  5JBB E;  3QMO A;  2BZ6 L;  4JZE L;  4NG9 L;  1KLO A;  1HRE A;  1APO A;  1DIY A;  1KIG L;  1NPE B;  2KNI A;  1HRF A;  2W86 A;  5JVZ A;  5L30 L;  1G1R A;  3R05 A;  1HZ8 A;  1DX5 I;  1PTH A;  2ADX A;  2P3F L;  5IKT A;  3TGF A;  1B9W A;  4MMZ B;  1LPZ A;  3HO3 A;  3FBY A;  3Q7D A;  2W3I B;  3IJE B;  5I46 L;  3SOQ A;  4LMF A;  3HS6 A;  2FLB L;  4O02 B;  3KL6 B;  2Y5F L;  4RS0 A;  1A3P A;  2VJ3 A;  4Z0K B;  1UZQ A;  2WPK E;  5KN5 C;  2Y80 B;  1XDT R;  1U67 A;  3KQE L;  4MMX B;  2VVC K;  2Y7X B;  2J2U B;  3CEN L;  6COX A;  4A7I A;  1IQL L;  1NT0 A;  2RA0 L;  1YUF A;  1HT8 A;  4RRX A;  1FFM A;  1N1I A;  1NFY B;  1XFE A;  2H9E L;  2P95 L;  2FZZ L;  3ASI A;  2FLR L;  1HT5 A;  1K37 A;  2K2T A;  3FFG L;  1ATA A;  1J9C L;  4M11 A;  5JB9 E;  5IKR A;  3TBD A;  2Y81 B;  2WPI E;  4ZHA B;  5IKV A;  1L5G B;  2I9B A;  1YGC L;  3LC3 B;  1URK A;  1EMN A;  5F1A A;  2P94 L;  1MQ6 L;  3N8X A;  2W3K B;  1EAI C;  2M74 A;  4ISI L;  4Y6D B;  2BOX A;  2RHP A;  2WG3 C;  1IQK L;  1IQE L;  4Y7A B;  3MDL A;  3KRK A;  4BDX A;  2VVU L;  1IQM L;  2RNL A;  2OYU P;  2J38 B;  1NFW B;  3LN0 A;  1EQH A;  4ZXX L;  3BT1 A;  4ZXY L;  1DVA L;  4NGA L;  2J34 B;  4ZAE B;  1KLJ L;  3P5B L;  1KSN B;  1CCF A;  4FM5 A;  2PUQ L;  1EMO A;  1G2L B;  3CFW A;  3N8W A;  3K9X A;  1FAK L;  1WHF A;  3LC5 B;  5F19 A;  4Y71 B;  3KQD L;  3LTG D;  1WHE A;  2BOH A;  1I0U A;  1K36 A;  2J4I B;  4RRY A;  2XC5 L;  5COX A;  2DDU A;  1FAX L;  3LN1 A;  3ZYG A;  3KK6 A;  5K0H B;  1FSB A;  3ENS A;  3ZYI B;  1W7X L;  2CJI B;  3M36 L;  2VWL L;  3TH3 L;  1XKB A;  3HS7 A;  4RRZ A;  1CQE A;  1F0R B;  3FCS B;  3ELA L;  2YGQ A;  3U7U G;  1P9J A;  1XKA L;  1M1X B;  1JBU L;  2BO2 A;  1IP0 A;  1AUT L;  1IQH L;  2VWM K;  2Y5G L;  4PH9 A;  4NA9 L;  1IVO C;  2VH0 B;  1FJS L;  1HAE A;  4YT7 L;  2G00 L;  2P16 L;  4Z6A L;  1RFN B;  2W26 B;  2WZP P;  1YUG A;  1IOE L;  2GD4 A;  2WPM E;  2XC4 L;  2P3T A;  1JL9 A;  3HS5 A;  5EGM B;  4BDW A;  4BTU A;  3TZI A;  2WG4 B;  3OLT A;  1F7M A;  2XBX L;  1HX2 A;  2VH6 B;  1EQG A;  3TK5 B;  1F7E A;  1LPG A;  3DEM A;  1LPK A;  2BQ6 A;  4CUF A;  3IIT B;  4CUD A;  1MOX C;  3PGH A;  3POY A;  5JB8 E;  2WFX B;  3H5C B;  1NZI A;  1DQB A;  3RR3 A;  1G1Q A;  3KQB L;  1ATE A;  3LTF B;  1FE2 A;  1EPJ A;  2P28 B;  2MHP A;  1NQL B;  2UWP B;  1C5M F;  1OB1 C;  5JBA E;  2WYJ B;  2XBY L;  1N7D A;  1EBV A;  1ZAQ A;  3OLU A;  4D0E A;  5JVY A;  3HO5 A;  1CVW L;  4Y76 B;  2VWO L;  2W2M E;  2J95 B;  1NFU B;  2H9E C;  1LMJ A;  1YUK B;  2VVV L;  4ZH8 B;  4BTT A;  2XBW L;  4C16 A;  2K2S B;  4JZD L;  3NTG A;  4O1Z A;  3BT2 A;  3HO4 A;  2I9A A;  2VWN L;  2W2O E;  3SOB B;  1ADX A;  4XLW A;  4X8S L;  4X8T L;  2D1J B;  4CUE A;  1U8C B;  1G1S A;  1G1T A;  2UWL B;  1IJQ A;  1WU1 B;  2KL7 A;  3Q3K B;  3N8Z A;  5KIR A;  3TK6 B;  2WFT A;  1ATD A;  1EPG A;  1EGF A;  5FDQ A;  4Y7B B;  5IKQ A;  3CA7 A;  3M37 L;  4BTI A;  4COX A;  2MGP A;  1TOZ A;  3N8Y B;  2FLG A;  4MMY B;  3ZYJ B;  1CEJ A;  2OYE P;  1KLI L;  2P93 L;  2WPH E;  4E1G A;  2BQW A;  1LMM A;  4LOR A;  1F0S B;  4Y79 B;  1UZJ A;  2AYL A;  1YO8 A;  3BPS E;  4CSY A;  4XL1 A;  1CVU A;  4A94 C;  2JKH L;  3SOV A;  2EI7 B;  1O5D L;  2KV4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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