3EBNA

A special dimerization of sars-cov main protease c-terminal domain due to domain-swapping
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
100
structure length
100
Chain Sequence
TTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title C-terminal domain of SARS-CoV main protease can form a 3D domain-swapped dimer
pubmed doi rcsb
molecule tags Hydrolase
source organism Sars coronavirus
molecule keywords Replicase polyprotein 1ab
total genus 24
structure length 100
sequence length 100
chains with identical sequence B, C, D
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2008-08-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1840.10 Mainly Alpha Orthogonal Bundle main proteinase (3clpro) structure, domain 3 main proteinase (3clpro) structure, domain 3 3ebnA00
4XFQA 3SNAA 3ATWA 4TWWA 2GX4A 4MDSA 1P9UA 2K7XA 2AMPA 2YNBA 3VB4A 1UJ1A 2Z3CA 2YNAA 4YLUA 2GTBA 2Z3DA 5EU8A 3VB5A 3TNSA 1Z1IA 3AW1A 3D23A 2AMDA 2GT8A 2QIQA 1UK2A 4YOJA 3F9HA 5B6OA 3E91A 3F9EA 4RSPA 2V6NA 4WMEA 3M3VA 3EBNA 5HYOA 2HOBA 2ZU4A 3SNCA 2Z9KA 1P9SA 3TNTA 2GZ7A 4ZUHA 3SN8A 3AVZA 2Z9JA 5C5OA 4YO9A 1LVOA 2AMQA 4WY3A 3SNBA 3F9FA 2D2DA 5C5NA 2GT7A 3TLOA 5C3NA 1UK4A 3EAJA 4TWYA 2Z94A 2C3SA 1UK3A 2OP9A 2VJ1A 1Q2WA 4WMFA 2ZU2A 2LIZA 2Q6FA 2A5IA 3D62A 2Z9LA 2A5KA 3EA9A 3VB7A 2H2ZA 2PWXA 2QCYA 2Z3EA 3EA8A 3TITA 3SNEA 2BX3A 4ZROA 2ALVA 3M3SA 2GZ9A 3M3TA 2Q6GA 5GWZA 4HI3A 2A5AA 3IWMA 2Q6DA 4WMDA 2ZU5A 3VB3A 1WOFA 3TIUA 2GZ8A 3EA7A 4YOIA 2Z9GA 3V3MA 3VB6A 2QC2A 4YOGA 2BX4A 1Z1JA 3AW0A 3F9GA 3FZDA 3SZNA 3SNDA 2DUCA 4F49A
chains in the Genus database with same CATH superfamily
4XFQA 3SNAA 3ATWA 4TWWA 2GX4A 4MDSA 1P9UA 2K7XA 2AMPA 2YNBA 3VB4A 1UJ1A 2Z3CA 2YNAA 4YLUA 2GTBA 2Z3DA 5EU8A 3VB5A 3TNSA 1Z1IA 3AW1A 3D23A 2AMDA 2GT8A 2QIQA 1UK2A 4YOJA 3F9HA 5B6OA 3E91A 3F9EA 4RSPA 2V6NA 4WMEA 3M3VA 3EBNA 5HYOA 2HOBA 2ZU4A 3SNCA 2Z9KA 1P9SA 3TNTA 2GZ7A 4ZUHA 3SN8A 3AVZA 2Z9JA 5C5OA 4YO9A 1LVOA 2AMQA 4WY3A 3SNBA 3F9FA 2D2DA 5C5NA 2GT7A 3TLOA 5C3NA 1UK4A 3EAJA 4TWYA 2Z94A 2C3SA 1UK3A 2OP9A 2VJ1A 1Q2WA 4WMFA 2ZU2A 2LIZA 2Q6FA 2A5IA 3D62A 2Z9LA 2A5KA 3EA9A 3VB7A 2H2ZA 2PWXA 2QCYA 2Z3EA 3EA8A 3TITA 3SNEA 2BX3A 4ZROA 2ALVA 3M3SA 2GZ9A 3M3TA 2Q6GA 5GWZA 4HI3A 2A5AA 3IWMA 2Q6DA 4WMDA 2ZU5A 3VB3A 1WOFA 3TIUA 2GZ8A 3EA7A 4YOIA 2Z9GA 3V3MA 3VB6A 2QC2A 4YOGA 2BX4A 1Z1JA 3AW0A 3F9GA 3FZDA 3SZNA 3SNDA 2DUCA 4F49A
chains in the Genus database with same CATH topology
4XFQA 3SNAA 3ATWA 4TWWA 2GX4A 4MDSA 1P9UA 2K7XA 2AMPA 2YNBA 3VB4A 1UJ1A 2Z3CA 2YNAA 4YLUA 2GTBA 2Z3DA 5EU8A 3VB5A 3TNSA 1Z1IA 3AW1A 3D23A 2AMDA 2GT8A 2QIQA 1UK2A 4YOJA 3F9HA 5B6OA 3E91A 3F9EA 4RSPA 2V6NA 4WMEA 3M3VA 3EBNA 5HYOA 2HOBA 2ZU4A 3SNCA 2Z9KA 1P9SA 3TNTA 2GZ7A 4ZUHA 3SN8A 3AVZA 2Z9JA 5C5OA 4YO9A 1LVOA 2AMQA 4WY3A 3SNBA 3F9FA 2D2DA 5C5NA 2GT7A 3TLOA 5C3NA 1UK4A 3EAJA 4TWYA 2Z94A 2C3SA 1UK3A 2OP9A 2VJ1A 1Q2WA 4WMFA 2ZU2A 2LIZA 2Q6FA 2A5IA 3D62A 2Z9LA 2A5KA 3EA9A 3VB7A 2H2ZA 2PWXA 2QCYA 2Z3EA 3EA8A 3TITA 3SNEA 2BX3A 4ZROA 2ALVA 3M3SA 2GZ9A 3M3TA 2Q6GA 5GWZA 4HI3A 2A5AA 3IWMA 2Q6DA 4WMDA 2ZU5A 3VB3A 1WOFA 3TIUA 2GZ8A 3EA7A 4YOIA 2Z9GA 3V3MA 3VB6A 2QC2A 4YOGA 2BX4A 1Z1JA 3AW0A 3F9GA 3FZDA 3SZNA 3SNDA 2DUCA 4F49A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XFQ A;  3SNA A;  3ATW A;  4TWW A;  2GX4 A;  4MDS A;  1P9U A;  2K7X A;  2AMP A;  2YNB A;  3VB4 A;  1UJ1 A;  2Z3C A;  2YNA A;  4YLU A;  2GTB A;  2Z3D A;  5EU8 A;  3VB5 A;  3TNS A;  1Z1I A;  3AW1 A;  3D23 A;  2AMD A;  2GT8 A;  2QIQ A;  1UK2 A;  4YOJ A;  3F9H A;  5B6O A;  3E91 A;  3F9E A;  4RSP A;  2V6N A;  4WME A;  3M3V A;  3EBN A;  5HYO A;  2HOB A;  2ZU4 A;  3SNC A;  2Z9K A;  1P9S A;  3TNT A;  2GZ7 A;  4ZUH A;  3SN8 A;  3AVZ A;  2Z9J A;  5C5O A;  4YO9 A;  1LVO A;  2AMQ A;  4WY3 A;  3SNB A;  3F9F A;  2D2D A;  5C5N A;  2GT7 A;  3TLO A;  5C3N A;  1UK4 A;  3EAJ A;  4TWY A;  2Z94 A;  2C3S A;  1UK3 A;  2OP9 A;  2VJ1 A;  1Q2W A;  4WMF A;  2ZU2 A;  2LIZ A;  2Q6F A;  2A5I A;  3D62 A;  2Z9L A;  2A5K A;  3EA9 A;  3VB7 A;  2H2Z A;  2PWX A;  2QCY A;  2Z3E A;  3EA8 A;  3TIT A;  3SNE A;  2BX3 A;  4ZRO A;  2ALV A;  3M3S A;  2GZ9 A;  3M3T A;  2Q6G A;  5GWZ A;  4HI3 A;  2A5A A;  3IWM A;  2Q6D A;  4WMD A;  2ZU5 A;  3VB3 A;  1WOF A;  3TIU A;  2GZ8 A;  3EA7 A;  4YOI A;  2Z9G A;  3V3M A;  3VB6 A;  2QC2 A;  4YOG A;  2BX4 A;  1Z1J A;  3AW0 A;  3F9G A;  3FZD A;  3SZN A;  3SND A;  2DUC A;  4F49 A; 
#chains in the Genus database with same CATH topology
 4XFQ A;  3SNA A;  3ATW A;  4TWW A;  2GX4 A;  4MDS A;  1P9U A;  2K7X A;  2AMP A;  2YNB A;  3VB4 A;  1UJ1 A;  2Z3C A;  2YNA A;  4YLU A;  2GTB A;  2Z3D A;  5EU8 A;  3VB5 A;  3TNS A;  1Z1I A;  3AW1 A;  3D23 A;  2AMD A;  2GT8 A;  2QIQ A;  1UK2 A;  4YOJ A;  3F9H A;  5B6O A;  3E91 A;  3F9E A;  4RSP A;  2V6N A;  4WME A;  3M3V A;  3EBN A;  5HYO A;  2HOB A;  2ZU4 A;  3SNC A;  2Z9K A;  1P9S A;  3TNT A;  2GZ7 A;  4ZUH A;  3SN8 A;  3AVZ A;  2Z9J A;  5C5O A;  4YO9 A;  1LVO A;  2AMQ A;  4WY3 A;  3SNB A;  3F9F A;  2D2D A;  5C5N A;  2GT7 A;  3TLO A;  5C3N A;  1UK4 A;  3EAJ A;  4TWY A;  2Z94 A;  2C3S A;  1UK3 A;  2OP9 A;  2VJ1 A;  1Q2W A;  4WMF A;  2ZU2 A;  2LIZ A;  2Q6F A;  2A5I A;  3D62 A;  2Z9L A;  2A5K A;  3EA9 A;  3VB7 A;  2H2Z A;  2PWX A;  2QCY A;  2Z3E A;  3EA8 A;  3TIT A;  3SNE A;  2BX3 A;  4ZRO A;  2ALV A;  3M3S A;  2GZ9 A;  3M3T A;  2Q6G A;  5GWZ A;  4HI3 A;  2A5A A;  3IWM A;  2Q6D A;  4WMD A;  2ZU5 A;  3VB3 A;  1WOF A;  3TIU A;  2GZ8 A;  3EA7 A;  4YOI A;  2Z9G A;  3V3M A;  3VB6 A;  2QC2 A;  4YOG A;  2BX4 A;  1Z1J A;  3AW0 A;  3F9G A;  3FZD A;  3SZN A;  3SND A;  2DUC A;  4F49 A; 
#chains in the Genus database with same CATH homology
 4XFQ A;  3SNA A;  3ATW A;  4TWW A;  2GX4 A;  4MDS A;  1P9U A;  2K7X A;  2AMP A;  2YNB A;  3VB4 A;  1UJ1 A;  2Z3C A;  2YNA A;  4YLU A;  2GTB A;  2Z3D A;  5EU8 A;  3VB5 A;  3TNS A;  1Z1I A;  3AW1 A;  3D23 A;  2AMD A;  2GT8 A;  2QIQ A;  1UK2 A;  4YOJ A;  3F9H A;  5B6O A;  3E91 A;  3F9E A;  4RSP A;  2V6N A;  4WME A;  3M3V A;  3EBN A;  5HYO A;  2HOB A;  2ZU4 A;  3SNC A;  2Z9K A;  1P9S A;  3TNT A;  2GZ7 A;  4ZUH A;  3SN8 A;  3AVZ A;  2Z9J A;  5C5O A;  4YO9 A;  1LVO A;  2AMQ A;  4WY3 A;  3SNB A;  3F9F A;  2D2D A;  5C5N A;  2GT7 A;  3TLO A;  5C3N A;  1UK4 A;  3EAJ A;  4TWY A;  2Z94 A;  2C3S A;  1UK3 A;  2OP9 A;  2VJ1 A;  1Q2W A;  4WMF A;  2ZU2 A;  2LIZ A;  2Q6F A;  2A5I A;  3D62 A;  2Z9L A;  2A5K A;  3EA9 A;  3VB7 A;  2H2Z A;  2PWX A;  2QCY A;  2Z3E A;  3EA8 A;  3TIT A;  3SNE A;  2BX3 A;  4ZRO A;  2ALV A;  3M3S A;  2GZ9 A;  3M3T A;  2Q6G A;  5GWZ A;  4HI3 A;  2A5A A;  3IWM A;  2Q6D A;  4WMD A;  2ZU5 A;  3VB3 A;  1WOF A;  3TIU A;  2GZ8 A;  3EA7 A;  4YOI A;  2Z9G A;  3V3M A;  3VB6 A;  2QC2 A;  4YOG A;  2BX4 A;  1Z1J A;  3AW0 A;  3F9G A;  3FZD A;  3SZN A;  3SND A;  2DUC A;  4F49 A; 
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similar chains in the Genus database (?% sequence similarity)
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