3GCWE

Pcsk9:egfa(h306y)
Total Genus 6
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
41
structure length
41
Chain Sequence
MGTNECLDNNGGCSYVCNDLKIGYECLCPDGFQLVAQRRCE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Antagonism of Secreted PCSK9 Increases Low Density Lipoprotein Receptor Expression in HepG2 Cells.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Proprotein convertase subtilisin/kexin type 9
total genus 6
structure length 41
sequence length 41
ec nomenclature
pdb deposition date 2009-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF12662 cEGF Complement Clr-like EGF-like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3gcwE00
1NFXB 4Y7AB 2BQWA 3CS7L 1TOZA 1FE2A 1O5DL 1HJ7A 4D90A 3NTBA 1Z6EL 3HO4A 1UZQA 3HS6A 1IQEL 2EI7B 2W2PE 3SOBB 3IJEB 3FBYA 1YUKB 1IGXA 2Y82B 2XC0L 2MGPA 4RS0A 2JKHL 1FAXL 2K2TA 1DX5I 3TK6B 2MHPA 1EBVA 5CKQA 1G2LB 3TK5B 1NT0A 3TZIA 2VVUL 2BOXA 2P94L 3MQEA 1K36A 4BDWA 1YUGA 2WPME 4X8UL 1HAEA 4E1GA 5JBBE 1APOA 4MMYB 1JV2B 5F1AA 2Y5FL 4NG9L 1QFKL 1A3PA 1G1SA 1ATDA 3K9XA 3NT1A 1URKA 1CQEA 1IQML 1EPIA 2P16L 4Z6AL 5JVZA 1WU1B 3EGFA 1IJQA 1HX2A 2G00L 4OTYA 4Y76B 1LQDA 1IQFL 2Y80B 4Y71B 1YGCL 1G1RA 1K37A 3GCXE 3HPTA 3TGFA 5CKNA 3LAQA 1B9WA 3LC5B 3ELAL 4JZDL 5JBAE 3KRKA 1CVUA 1XKBA 1FFMA 1SZBA 2RHPA 5JW1A 1EAIC 2J34B 2AYLA 3NTGA 1COUA 2DDUA 1HT8A 4Y6DB 2I9BA 2BQ7A 2FD6A 1ATBA 3TH3L 2BQ6A 2UWLB 4M11A 1EMNA 3BT1A 3N8VA 2B7DL 2WPJE 1YUFA 1C5MF 2I9AA 2W3IB 1F0SB 4G1MB 1ATAA 5CKMA 5E8DA 1DQBA 1DDXA 2J95B 4BTUA 5I46L 1DVAL 1CEJA 4ZH8B 1EPHA 4NA9L 4BDXA 1UZKA 3ZYGA 1MQ5L 1DIYA 3ENSA 2VJ3A 3ZYJB 1BF9A 4CUEA 3R05A 3P5BL 2YGOA 1IQHL 1PTHA 2RNLA 2XC4L 1KLJL 2WG4B 1CX2A 5K0HB 5EGMB 5FDQA 2RA0L 3KQBL 4JZEL 4NGAL 2FLBL 2VWMK 2CJIB 4M10A 6COXA 4CUDA 4XLWA 2WFTA 4ZXXL 1J9CL 4BTIA 2BOHA 1EPGA 4ISHL 1L5GB 3LTGD 2P3TA 4O02B 3H5CB 4RRYA 2BOKL 1IP0A 1NQLB 3GCWE 5JBCE 1WHFA 1OB1C 1HREA 1F0RB 5CISA 2P3FL 1F7MA 1IOXA 2J2UB 4RUTA 2BOUA 3LC3B 1IOEL 4ZAEB 4MMZB 1IQLL 5JB8E 2KL7A 4Z0LA 5COXA 5L2ZL 5F19A 1W7XL 3KQEL 3KK6A 1RFNB 2KB9A 2XBXL 1N7DA 1NFYB 5L30L 2WG3C 2Y7ZB 1IQKL 1M1XB 5IKQA 1Z6CA 2PUQL 1XFEA 5IKTA 2OYUP 3POYA 2K2SB 1HCGB 4FM5A 3LN0A 1IGZA 2EI8B 4BTTA 2P26A 3SOVA 3DEMA 3HO5A 2WYGB 2WYJB 1GK5A 1FJSL 1EMOA 1YO8A 2XC5L 3CA7A 3CFWA 1PGEA 3PGHA 3F1SB 4Y7BB 3N8WB 5KIRA 3N8YA 2UWOB 3LIWB 2VWOL 2Y38A 2FLRL 3HS7A 1MQ6L 2Y5HL 1WHEA 4X8SL 3KL6B 1TPGA 4XBMA 3U73A 4A7IA 5IKVA 1PXXA 1HT5A 3OLTA 2XBWL 3QMOA 4JYUL 2W3KB 1IQGL 4X8VL 2WPLE 1AUTL 1JL9A 1LPKA 3QCWA 1EQHA 2VVVL 1W8BL 3KCGL 2P3UA 2H9EL 4YZUB 4ZHAB 1KLIL 3TBDA 2W2OE 4LORA 4OTJA 3NJPC 1NFWB 1CCVA 2P93L 4RRWA 2M74A 4C16A 3CENL 3U7UG 2VH6B 1APQA 2W26B 3IITB 2VH0B 1LPGA 2NPRA 2VVCK 3KQDL 1ADXA 2XBYL 3BPSE 3V64C 2VWLL 3ZYIB 1NZIA 4JYVL 3HS5A 2Y7XB 2KV4A 2UWPB 3N8YB 4CUFA 1NPEB 4Z0KB 5L2YL 1CCFA 3LTFB 2OYEP 1Q4GA 2W2ME 4BXSA 1L3YA 2Y81B 1U67A 4Y79B 1XDTR 1MOXC 1P0SL 4ZXYL 3FCSB 3M36L 5IKRA 2P3FN 4X8TL 3N8WA 3ASIA 1G1TA 2J94B 2MGRA 3FFGL 3GISX 3N8ZA 3SW2A 1HZ8A 5JVYA 1LPZA 2VWNL 2W2QE 3F6UL 1UZJA 4RRXA 3M37L 4D0EA 4YT7L 1IQNL 1NFUB 1IQIL 2P95L 1FSBA 2J38B 3V65B 1V3XB 2XBVL 1IVOC 1KIGL 3C9AC 2PHBB 3MDLA 2WPHE 2J4IB 2Y5GL 1ATEA 1HRFA 5KN5C 3KQCL 1ZAQA 1EPJA 3LN1A 2YGPA 3OLUA 1I0UA 2TGFA 2WPIE 1KSNB 4COXA 3BT2A 2ADXA 1HAFA 4LMFA 1EZQB 4JZFL 2WPKE 1UZPA 2D1JB 1XKAL 1IQJL 1U8CB 1G1QA 4MMXB 1G2MB 1PFXL 2BZ6L 3QH0A 1TLEA 2WFXB 2BMGA 1X7AL 1P9JA 4D0FA 2Q1JB 3N8XA 4PH9A 1FAKL 2BO2A 4O1ZA 4YT6L 5JB9E 2FLGA 1EGFA 4CSYA 2EI6B 1EQGA 3Q3KB 3SOQA 1N1IA 1CVWL 2W86A 4XL1A 2GD4A 2F9BL 2P28B 1JBUL 1F7EA 3HO3A 3RR3A 2FZZL 2W2NE 4ISIL 4RRZA 4TGFA 1FF7A 4AQTA 3Q7DA 1PRHA 4BXWA 1LMJA 1KLOA 2PR3B
chains in the Genus database with same CATH superfamily
1NFXB 4Y7AB 2BQWA 3CS7L 1TOZA 1FE2A 1O5DL 1HJ7A 4D90A 3NTBA 1Z6EL 3HO4A 1UZQA 3HS6A 1IQEL 2EI7B 2W2PE 3SOBB 3IJEB 3FBYA 1YUKB 1IGXA 2Y82B 2XC0L 2MGPA 4RS0A 2JKHL 1FAXL 2K2TA 1DX5I 3TK6B 2MHPA 1EBVA 5CKQA 1G2LB 3TK5B 1NT0A 3TZIA 2JJLA 2VVUL 2BOXA 2P94L 3MQEA 1K36A 4BDWA 1YUGA 2WPME 4X8UL 1HAEA 2WZPP 4E1GA 5JBBE 1APOA 4MMYB 1JV2B 5F1AA 2Y5FL 4NG9L 1QFKL 1A3PA 1G1SA 1ATDA 3K9XA 3NT1A 1URKA 1CQEA 1IQML 1EPIA 2P16L 4Z6AL 5JVZA 1WU1B 3EGFA 1IJQA 1HX2A 2G00L 4OTYA 4Y76B 1LQDA 1IQFL 2Y80B 4Y71B 1YGCL 1G1RA 1K37A 3GCXE 3HPTA 4GU3A 3TGFA 5CKNA 3LAQA 1B9WA 3LC5B 3ELAL 4JZDL 5JBAE 3KRKA 1CVUA 1XKBA 1FFMA 1SZBA 2RHPA 5JW1A 1EAIC 2J34B 2AYLA 2BT8A 3NTGA 1COUA 2DDUA 1HT8A 4Y6DB 2I9BA 2BQ7A 2FD6A 1ATBA 3TH3L 2BQ6A 2UWLB 4M11A 1EMNA 3BT1A 3N8VA 2B7DL 2WPJE 1YUFA 1C5MF 2I9AA 2W3IB 1F0SB 4G1MB 1ATAA 5CKMA 5E8DA 1DQBA 1DDXA 2J95B 4BTUA 5I46L 4A94C 1DVAL 1CEJA 4ZH8B 1EPHA 4NA9L 4BDXA 1UZKA 2HOXA 3ZYGA 1MQ5L 1DIYA 3ENSA 2VJ3A 3ZYJB 1BF9A 4CUEA 2VRSA 3R05A 3P5BL 2YGOA 1IQHL 1KKEA 1PTHA 2RNLA 2XC4L 1KLJL 2WG4B 1CX2A 5K0HB 5EGMB 5FDQA 2RA0L 3KQBL 4JZEL 2KNIA 4NGAL 2FLBL 2VWMK 2CJIB 4M10A 6COXA 4CUDA 4XLWA 2WFTA 4ZXXL 1J9CL 4BTIA 2BOHA 1EPGA 4ISHL 1L5GB 3LTGD 2P3TA 4O02B 3H5CB 4RRYA 2BOKL 1IP0A 1NQLB 3GCWE 5JBCE 1WHFA 1OB1C 1HREA 1F0RB 5CISA 2P3FL 1F7MA 1IOXA 2J2UB 4RUTA 2BOUA 3LC3B 1IOEL 4ZAEB 4MMZB 1IQLL 5JB8E 2KL7A 4Z0LA 5COXA 5L2ZL 5F19A 1W7XL 3KQEL 3KK6A 1RFNB 2KB9A 2XBXL 1N7DA 1NFYB 5L30L 2WG3C 2Y7ZB 1IQKL 1M1XB 5IKQA 1Z6CA 2PUQL 1XFEA 5IKTA 2OYUP 3POYA 2K2SB 1HCGB 4FM5A 3LN0A 1QIUA 1IGZA 2EI8B 4BTTA 2P26A 2YGQA 3SOVA 3DEMA 3HO5A 2WYGB 2WYJB 1GK5A 1FJSL 1EMOA 1YO8A 2XC5L 3CA7A 3CFWA 1PGEA 3PGHA 3F1SB 4Y7BB 3N8WB 5KIRA 3N8YA 2UWOB 3LIWB 2VWOL 2Y38A 2FLRL 4GU4A 3HS7A 1MQ6L 2Y5HL 1WHEA 4X8SL 3KL6B 1TPGA 4XBMA 3U73A 4A7IA 5IKVA 1PXXA 1HT5A 3OLTA 2XBWL 3QMOA 4JYUL 2W3KB 1IQGL 4X8VL 2WPLE 1AUTL 1JL9A 1LPKA 3QCWA 1EQHA 2VVVL 1W8BL 3KCGL 2P3UA 2H9EL 4YZUB 4ZHAB 1KLIL 3TBDA 2W2OE 4LORA 4OTJA 3NJPC 1NFWB 1CCVA 2P93L 4RRWA 2M74A 4C16A 3CENL 1V1HA 3U7UG 2VH6B 1APQA 2W26B 3IITB 2VH0B 1LPGA 2NPRA 2VVCK 3KQDL 1ADXA 2XBYL 3BPSE 3V64C 2VWLL 3ZYIB 1NZIA 4JYVL 3HS5A 1LMMA 2Y7XB 2KV4A 2UWPB 3N8YB 4CUFA 1NPEB 4Z0KB 5L2YL 1CCFA 3LTFB 2BT7A 2OYEP 1Q4GA 2W2ME 4BXSA 1L3YA 2Y81B 1U67A 4Y79B 1XDTR 1MOXC 1P0SL 4ZXYL 3FCSB 3M36L 5IKRA 2P3FN 4X8TL 3N8WA 3ASIA 1G1TA 2J94B 2MGRA 3FFGL 3GISX 3N8ZA 3SW2A 1HZ8A 5JVYA 1LPZA 2VWNL 2W2QE 3F6UL 1UZJA 4RRXA 3M37L 4D0EA 4YT7L 1IQNL 1NFUB 1IQIL 2P95L 1FSBA 2J38B 3V65B 1V3XB 2XBVL 1IVOC 1KIGL 3C9AC 2PHBB 3MDLA 2WPHE 2J4IB 2Y5GL 1ATEA 1HRFA 5KN5C 3KQCL 1ZAQA 1EPJA 1LK9A 3LN1A 2YGPA 3OLUA 1I0UA 2TGFA 2WPIE 1KSNB 4COXA 3BT2A 2ADXA 1HAFA 4LMFA 1EZQB 4JZFL 2HORA 2WPKE 1UZPA 2D1JB 2H9EC 1XKAL 1IQJL 1U8CB 1G1QA 4MMXB 1G2MB 1PFXL 2BZ6L 3QH0A 1TLEA 2WFXB 3S6XA 2BMGA 1X7AL 1P9JA 4D0FA 2Q1JB 3N8XA 4PH9A 1FAKL 2BO2A 4O1ZA 4YT6L 5JB9E 2FLGA 1EGFA 4CSYA 2EI6B 1EQGA 3Q3KB 3SOQA 1N1IA 1CVWL 2W86A 4XL1A 2GD4A 2F9BL 2BSFA 2P28B 1JBUL 1F7EA 1V1IA 3HO3A 3RR3A 2FZZL 2W2NE 4ISIL 4RRZA 4TGFA 1FF7A 4AQTA 3Q7DA 1PRHA 4BXWA 1LMJA 1KLOA 2PR3B
chains in the Genus database with same CATH topology
1NFXB 4Y7AB 2BQWA 3CS7L 1TOZA 1FE2A 1O5DL 1HJ7A 4D90A 3NTBA 1Z6EL 3HO4A 1UZQA 3HS6A 1IQEL 2EI7B 2W2PE 3SOBB 3IJEB 3FBYA 1YUKB 1IGXA 2Y82B 2XC0L 2MGPA 4RS0A 2JKHL 1FAXL 2K2TA 1DX5I 3TK6B 2MHPA 1EBVA 5CKQA 1G2LB 3TK5B 1NT0A 3TZIA 2VVUL 2BOXA 2P94L 3MQEA 1K36A 4BDWA 1YUGA 2WPME 4X8UL 1HAEA 2WZPP 4E1GA 5JBBE 1APOA 4MMYB 1JV2B 5F1AA 2Y5FL 4NG9L 1QFKL 1A3PA 1G1SA 1ATDA 3K9XA 3NT1A 1URKA 1CQEA 1IQML 1EPIA 2P16L 4Z6AL 5JVZA 1WU1B 3EGFA 1IJQA 1HX2A 2G00L 4OTYA 4Y76B 1LQDA 1IQFL 2Y80B 4Y71B 1YGCL 1G1RA 1K37A 3GCXE 3HPTA 3TGFA 5CKNA 3LAQA 1B9WA 3LC5B 3ELAL 4JZDL 5JBAE 3KRKA 1CVUA 1XKBA 1FFMA 1SZBA 2RHPA 5JW1A 1EAIC 2J34B 2AYLA 3NTGA 1COUA 2DDUA 1HT8A 4Y6DB 2I9BA 2BQ7A 2FD6A 1ATBA 3TH3L 2BQ6A 2UWLB 4M11A 1EMNA 3BT1A 3N8VA 2B7DL 2WPJE 1YUFA 1C5MF 2I9AA 2W3IB 1F0SB 4G1MB 1ATAA 5CKMA 5E8DA 1DQBA 1DDXA 2J95B 4BTUA 5I46L 4A94C 1DVAL 1CEJA 4ZH8B 1EPHA 4NA9L 4BDXA 1UZKA 3ZYGA 1MQ5L 1DIYA 3ENSA 2VJ3A 3ZYJB 1BF9A 4CUEA 3R05A 3P5BL 2YGOA 1IQHL 1PTHA 2RNLA 2XC4L 1KLJL 2WG4B 1CX2A 5K0HB 5EGMB 5FDQA 2RA0L 3KQBL 4JZEL 2KNIA 4NGAL 2FLBL 2VWMK 2CJIB 4M10A 6COXA 4CUDA 4XLWA 2WFTA 4ZXXL 1J9CL 4BTIA 2BOHA 1EPGA 4ISHL 1L5GB 3LTGD 2P3TA 4O02B 3H5CB 4RRYA 2BOKL 1IP0A 1NQLB 3GCWE 5JBCE 1WHFA 1OB1C 1HREA 1F0RB 5CISA 2P3FL 1F7MA 1IOXA 2J2UB 4RUTA 2BOUA 3LC3B 1IOEL 4ZAEB 4MMZB 1IQLL 5JB8E 2KL7A 4Z0LA 5COXA 5L2ZL 5F19A 1W7XL 3KQEL 3KK6A 1RFNB 2KB9A 2XBXL 1N7DA 1NFYB 5L30L 2WG3C 2Y7ZB 1IQKL 1M1XB 5IKQA 1Z6CA 2PUQL 1XFEA 5IKTA 2OYUP 3POYA 2K2SB 1HCGB 4FM5A 3LN0A 1IGZA 2EI8B 4BTTA 2P26A 2YGQA 3SOVA 3DEMA 3HO5A 2WYGB 2WYJB 1GK5A 1FJSL 1EMOA 1YO8A 2XC5L 3CA7A 3CFWA 1PGEA 3PGHA 3F1SB 4Y7BB 3N8WB 5KIRA 3N8YA 2UWOB 3LIWB 2VWOL 2Y38A 2FLRL 3HS7A 1MQ6L 2Y5HL 1WHEA 4X8SL 3KL6B 1TPGA 4XBMA 3U73A 4A7IA 5IKVA 1PXXA 1HT5A 3OLTA 2XBWL 3QMOA 4JYUL 2W3KB 1IQGL 4X8VL 2WPLE 1AUTL 1JL9A 1LPKA 3QCWA 1EQHA 2VVVL 1W8BL 3KCGL 2P3UA 2H9EL 4YZUB 4ZHAB 1KLIL 3TBDA 2W2OE 4LORA 4OTJA 3NJPC 1NFWB 1CCVA 2P93L 4RRWA 2M74A 4C16A 3CENL 3U7UG 2VH6B 1APQA 2W26B 3IITB 2VH0B 1LPGA 2NPRA 2VVCK 3KQDL 1ADXA 2XBYL 3BPSE 3V64C 2VWLL 3ZYIB 1NZIA 4JYVL 3HS5A 1LMMA 2Y7XB 2KV4A 2UWPB 3N8YB 4CUFA 1NPEB 4Z0KB 5L2YL 1CCFA 3LTFB 2OYEP 1Q4GA 2W2ME 4BXSA 1L3YA 2Y81B 1U67A 4Y79B 1XDTR 1MOXC 1P0SL 4ZXYL 3FCSB 3M36L 5IKRA 2P3FN 4X8TL 3N8WA 3ASIA 1G1TA 2J94B 2MGRA 3FFGL 3GISX 3N8ZA 3SW2A 1HZ8A 5JVYA 1LPZA 2VWNL 2W2QE 3F6UL 1UZJA 4RRXA 3M37L 4D0EA 4YT7L 1IQNL 1NFUB 1IQIL 2P95L 1FSBA 2J38B 3V65B 1V3XB 2XBVL 1IVOC 1KIGL 3C9AC 2PHBB 3MDLA 2WPHE 2J4IB 2Y5GL 1ATEA 1HRFA 5KN5C 3KQCL 1ZAQA 1EPJA 3LN1A 2YGPA 3OLUA 1I0UA 2TGFA 2WPIE 1KSNB 4COXA 3BT2A 2ADXA 1HAFA 4LMFA 1EZQB 4JZFL 2WPKE 1UZPA 2D1JB 2H9EC 1XKAL 1IQJL 1U8CB 1G1QA 4MMXB 1G2MB 1PFXL 2BZ6L 3QH0A 1TLEA 2WFXB 3S6XA 2BMGA 1X7AL 1P9JA 4D0FA 2Q1JB 3N8XA 4PH9A 1FAKL 2BO2A 4O1ZA 4YT6L 5JB9E 2FLGA 1EGFA 4CSYA 2EI6B 1EQGA 3Q3KB 3SOQA 1N1IA 1CVWL 2W86A 4XL1A 2GD4A 2F9BL 2P28B 1JBUL 1F7EA 3HO3A 3RR3A 2FZZL 2W2NE 4ISIL 4RRZA 4TGFA 1FF7A 4AQTA 3Q7DA 1PRHA 4BXWA 1LMJA 1KLOA 2PR3B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NFX B;  4Y7A B;  2BQW A;  3CS7 L;  1TOZ A;  1FE2 A;  1O5D L;  1HJ7 A;  4D90 A;  3NTB A;  1Z6E L;  3HO4 A;  1UZQ A;  3HS6 A;  1IQE L;  2EI7 B;  2W2P E;  3SOB B;  3IJE B;  3FBY A;  1YUK B;  1IGX A;  2Y82 B;  2XC0 L;  2MGP A;  4RS0 A;  2JKH L;  1FAX L;  2K2T A;  1DX5 I;  3TK6 B;  2MHP A;  1EBV A;  5CKQ A;  1G2L B;  3TK5 B;  1NT0 A;  3TZI A;  2VVU L;  2BOX A;  2P94 L;  3MQE A;  1K36 A;  4BDW A;  1YUG A;  2WPM E;  4X8U L;  1HAE A;  4E1G A;  5JBB E;  1APO A;  4MMY B;  1JV2 B;  5F1A A;  2Y5F L;  4NG9 L;  1QFK L;  1A3P A;  1G1S A;  1ATD A;  3K9X A;  3NT1 A;  1URK A;  1CQE A;  1IQM L;  1EPI A;  2P16 L;  4Z6A L;  5JVZ A;  1WU1 B;  3EGF A;  1IJQ A;  1HX2 A;  2G00 L;  4OTY A;  4Y76 B;  1LQD A;  1IQF L;  2Y80 B;  4Y71 B;  1YGC L;  1G1R A;  1K37 A;  3GCX E;  3HPT A;  3TGF A;  5CKN A;  3LAQ A;  1B9W A;  3LC5 B;  3ELA L;  4JZD L;  5JBA E;  3KRK A;  1CVU A;  1XKB A;  1FFM A;  1SZB A;  2RHP A;  5JW1 A;  1EAI C;  2J34 B;  2AYL A;  3NTG A;  1COU A;  2DDU A;  1HT8 A;  4Y6D B;  2I9B A;  2BQ7 A;  2FD6 A;  1ATB A;  3TH3 L;  2BQ6 A;  2UWL B;  4M11 A;  1EMN A;  3BT1 A;  3N8V A;  2B7D L;  2WPJ E;  1YUF A;  1C5M F;  2I9A A;  2W3I B;  1F0S B;  4G1M B;  1ATA A;  5CKM A;  5E8D A;  1DQB A;  1DDX A;  2J95 B;  4BTU A;  5I46 L;  1DVA L;  1CEJ A;  4ZH8 B;  1EPH A;  4NA9 L;  4BDX A;  1UZK A;  3ZYG A;  1MQ5 L;  1DIY A;  3ENS A;  2VJ3 A;  3ZYJ B;  1BF9 A;  4CUE A;  3R05 A;  3P5B L;  2YGO A;  1IQH L;  1PTH A;  2RNL A;  2XC4 L;  1KLJ L;  2WG4 B;  1CX2 A;  5K0H B;  5EGM B;  5FDQ A;  2RA0 L;  3KQB L;  4JZE L;  4NGA L;  2FLB L;  2VWM K;  2CJI B;  4M10 A;  6COX A;  4CUD A;  4XLW A;  2WFT A;  4ZXX L;  1J9C L;  4BTI A;  2BOH A;  1EPG A;  4ISH L;  1L5G B;  3LTG D;  2P3T A;  4O02 B;  3H5C B;  4RRY A;  2BOK L;  1IP0 A;  1NQL B;  3GCW E;  5JBC E;  1WHF A;  1OB1 C;  1HRE A;  1F0R B;  5CIS A;  2P3F L;  1F7M A;  1IOX A;  2J2U B;  4RUT A;  2BOU A;  3LC3 B;  1IOE L;  4ZAE B;  4MMZ B;  1IQL L;  5JB8 E;  2KL7 A;  4Z0L A;  5COX A;  5L2Z L;  5F19 A;  1W7X L;  3KQE L;  3KK6 A;  1RFN B;  2KB9 A;  2XBX L;  1N7D A;  1NFY B;  5L30 L;  2WG3 C;  2Y7Z B;  1IQK L;  1M1X B;  5IKQ A;  1Z6C A;  2PUQ L;  1XFE A;  5IKT A;  2OYU P;  3POY A;  2K2S B;  1HCG B;  4FM5 A;  3LN0 A;  1IGZ A;  2EI8 B;  4BTT A;  2P26 A;  3SOV A;  3DEM A;  3HO5 A;  2WYG B;  2WYJ B;  1GK5 A;  1FJS L;  1EMO A;  1YO8 A;  2XC5 L;  3CA7 A;  3CFW A;  1PGE A;  3PGH A;  3F1S B;  4Y7B B;  3N8W B;  5KIR A;  3N8Y A;  2UWO B;  3LIW B;  2VWO L;  2Y38 A;  2FLR L;  3HS7 A;  1MQ6 L;  2Y5H L;  1WHE A;  4X8S L;  3KL6 B;  1TPG A;  4XBM A;  3U73 A;  4A7I A;  5IKV A;  1PXX A;  1HT5 A;  3OLT A;  2XBW L;  3QMO A;  4JYU L;  2W3K B;  1IQG L;  4X8V L;  2WPL E;  1AUT L;  1JL9 A;  1LPK A;  3QCW A;  1EQH A;  2VVV L;  1W8B L;  3KCG L;  2P3U A;  2H9E L;  4YZU B;  4ZHA B;  1KLI L;  3TBD A;  2W2O E;  4LOR A;  4OTJ A;  3NJP C;  1NFW B;  1CCV A;  2P93 L;  4RRW A;  2M74 A;  4C16 A;  3CEN L;  3U7U G;  2VH6 B;  1APQ A;  2W26 B;  3IIT B;  2VH0 B;  1LPG A;  2NPR A;  2VVC K;  3KQD L;  1ADX A;  2XBY L;  3BPS E;  3V64 C;  2VWL L;  3ZYI B;  1NZI A;  4JYV L;  3HS5 A;  2Y7X B;  2KV4 A;  2UWP B;  3N8Y B;  4CUF A;  1NPE B;  4Z0K B;  5L2Y L;  1CCF A;  3LTF B;  2OYE P;  1Q4G A;  2W2M E;  4BXS A;  1L3Y A;  2Y81 B;  1U67 A;  4Y79 B;  1XDT R;  1MOX C;  1P0S L;  4ZXY L;  3FCS B;  3M36 L;  5IKR A;  2P3F N;  4X8T L;  3N8W A;  3ASI A;  1G1T A;  2J94 B;  2MGR A;  3FFG L;  3GIS X;  3N8Z A;  3SW2 A;  1HZ8 A;  5JVY A;  1LPZ A;  2VWN L;  2W2Q E;  3F6U L;  1UZJ A;  4RRX A;  3M37 L;  4D0E A;  4YT7 L;  1IQN L;  1NFU B;  1IQI L;  2P95 L;  1FSB A;  2J38 B;  3V65 B;  1V3X B;  2XBV L;  1IVO C;  1KIG L;  3C9A C;  2PHB B;  3MDL A;  2WPH E;  2J4I B;  2Y5G L;  1ATE A;  1HRF A;  5KN5 C;  3KQC L;  1ZAQ A;  1EPJ A;  3LN1 A;  2YGP A;  3OLU A;  1I0U A;  2TGF A;  2WPI E;  1KSN B;  4COX A;  3BT2 A;  2ADX A;  1HAF A;  4LMF A;  1EZQ B;  4JZF L;  2WPK E;  1UZP A;  2D1J B;  1XKA L;  1IQJ L;  1U8C B;  1G1Q A;  4MMX B;  1G2M B;  1PFX L;  2BZ6 L;  3QH0 A;  1TLE A;  2WFX B;  2BMG A;  1X7A L;  1P9J A;  4D0F A;  2Q1J B;  3N8X A;  4PH9 A;  1FAK L;  2BO2 A;  4O1Z A;  4YT6 L;  5JB9 E;  2FLG A;  1EGF A;  4CSY A;  2EI6 B;  1EQG A;  3Q3K B;  3SOQ A;  1N1I A;  1CVW L;  2W86 A;  4XL1 A;  2GD4 A;  2F9B L;  2P28 B;  1JBU L;  1F7E A;  3HO3 A;  3RR3 A;  2FZZ L;  2W2N E;  4ISI L;  4RRZ A;  4TGF A;  1FF7 A;  4AQT A;  3Q7D A;  1PRH A;  4BXW A;  1LMJ A;  1KLO A;  2PR3 B; 
#chains in the Genus database with same CATH topology
 1NFX B;  4Y7A B;  2BQW A;  3CS7 L;  1TOZ A;  1FE2 A;  1O5D L;  1HJ7 A;  4D90 A;  3NTB A;  1Z6E L;  3HO4 A;  1UZQ A;  3HS6 A;  1IQE L;  2EI7 B;  2W2P E;  3SOB B;  3IJE B;  3FBY A;  1YUK B;  1IGX A;  2Y82 B;  2XC0 L;  2MGP A;  4RS0 A;  2JKH L;  1FAX L;  2K2T A;  1DX5 I;  3TK6 B;  2MHP A;  1EBV A;  5CKQ A;  1G2L B;  3TK5 B;  1NT0 A;  3TZI A;  2JJL A;  2VVU L;  2BOX A;  2P94 L;  3MQE A;  1K36 A;  4BDW A;  1YUG A;  2WPM E;  4X8U L;  1HAE A;  2WZP P;  4E1G A;  5JBB E;  1APO A;  4MMY B;  1JV2 B;  5F1A A;  2Y5F L;  4NG9 L;  1QFK L;  1A3P A;  1G1S A;  1ATD A;  3K9X A;  3NT1 A;  1URK A;  1CQE A;  1IQM L;  1EPI A;  2P16 L;  4Z6A L;  5JVZ A;  1WU1 B;  3EGF A;  1IJQ A;  1HX2 A;  2G00 L;  4OTY A;  4Y76 B;  1LQD A;  1IQF L;  2Y80 B;  4Y71 B;  1YGC L;  1G1R A;  1K37 A;  3GCX E;  3HPT A;  4GU3 A;  3TGF A;  5CKN A;  3LAQ A;  1B9W A;  3LC5 B;  3ELA L;  4JZD L;  5JBA E;  3KRK A;  1CVU A;  1XKB A;  1FFM A;  1SZB A;  2RHP A;  5JW1 A;  1EAI C;  2J34 B;  2AYL A;  2BT8 A;  3NTG A;  1COU A;  2DDU A;  1HT8 A;  4Y6D B;  2I9B A;  2BQ7 A;  2FD6 A;  1ATB A;  3TH3 L;  2BQ6 A;  2UWL B;  4M11 A;  1EMN A;  3BT1 A;  3N8V A;  2B7D L;  2WPJ E;  1YUF A;  1C5M F;  2I9A A;  2W3I B;  1F0S B;  4G1M B;  1ATA A;  5CKM A;  5E8D A;  1DQB A;  1DDX A;  2J95 B;  4BTU A;  5I46 L;  4A94 C;  1DVA L;  1CEJ A;  4ZH8 B;  1EPH A;  4NA9 L;  4BDX A;  1UZK A;  2HOX A;  3ZYG A;  1MQ5 L;  1DIY A;  3ENS A;  2VJ3 A;  3ZYJ B;  1BF9 A;  4CUE A;  2VRS A;  3R05 A;  3P5B L;  2YGO A;  1IQH L;  1KKE A;  1PTH A;  2RNL A;  2XC4 L;  1KLJ L;  2WG4 B;  1CX2 A;  5K0H B;  5EGM B;  5FDQ A;  2RA0 L;  3KQB L;  4JZE L;  2KNI A;  4NGA L;  2FLB L;  2VWM K;  2CJI B;  4M10 A;  6COX A;  4CUD A;  4XLW A;  2WFT A;  4ZXX L;  1J9C L;  4BTI A;  2BOH A;  1EPG A;  4ISH L;  1L5G B;  3LTG D;  2P3T A;  4O02 B;  3H5C B;  4RRY A;  2BOK L;  1IP0 A;  1NQL B;  3GCW E;  5JBC E;  1WHF A;  1OB1 C;  1HRE A;  1F0R B;  5CIS A;  2P3F L;  1F7M A;  1IOX A;  2J2U B;  4RUT A;  2BOU A;  3LC3 B;  1IOE L;  4ZAE B;  4MMZ B;  1IQL L;  5JB8 E;  2KL7 A;  4Z0L A;  5COX A;  5L2Z L;  5F19 A;  1W7X L;  3KQE L;  3KK6 A;  1RFN B;  2KB9 A;  2XBX L;  1N7D A;  1NFY B;  5L30 L;  2WG3 C;  2Y7Z B;  1IQK L;  1M1X B;  5IKQ A;  1Z6C A;  2PUQ L;  1XFE A;  5IKT A;  2OYU P;  3POY A;  2K2S B;  1HCG B;  4FM5 A;  3LN0 A;  1QIU A;  1IGZ A;  2EI8 B;  4BTT A;  2P26 A;  2YGQ A;  3SOV A;  3DEM A;  3HO5 A;  2WYG B;  2WYJ B;  1GK5 A;  1FJS L;  1EMO A;  1YO8 A;  2XC5 L;  3CA7 A;  3CFW A;  1PGE A;  3PGH A;  3F1S B;  4Y7B B;  3N8W B;  5KIR A;  3N8Y A;  2UWO B;  3LIW B;  2VWO L;  2Y38 A;  2FLR L;  4GU4 A;  3HS7 A;  1MQ6 L;  2Y5H L;  1WHE A;  4X8S L;  3KL6 B;  1TPG A;  4XBM A;  3U73 A;  4A7I A;  5IKV A;  1PXX A;  1HT5 A;  3OLT A;  2XBW L;  3QMO A;  4JYU L;  2W3K B;  1IQG L;  4X8V L;  2WPL E;  1AUT L;  1JL9 A;  1LPK A;  3QCW A;  1EQH A;  2VVV L;  1W8B L;  3KCG L;  2P3U A;  2H9E L;  4YZU B;  4ZHA B;  1KLI L;  3TBD A;  2W2O E;  4LOR A;  4OTJ A;  3NJP C;  1NFW B;  1CCV A;  2P93 L;  4RRW A;  2M74 A;  4C16 A;  3CEN L;  1V1H A;  3U7U G;  2VH6 B;  1APQ A;  2W26 B;  3IIT B;  2VH0 B;  1LPG A;  2NPR A;  2VVC K;  3KQD L;  1ADX A;  2XBY L;  3BPS E;  3V64 C;  2VWL L;  3ZYI B;  1NZI A;  4JYV L;  3HS5 A;  1LMM A;  2Y7X B;  2KV4 A;  2UWP B;  3N8Y B;  4CUF A;  1NPE B;  4Z0K B;  5L2Y L;  1CCF A;  3LTF B;  2BT7 A;  2OYE P;  1Q4G A;  2W2M E;  4BXS A;  1L3Y A;  2Y81 B;  1U67 A;  4Y79 B;  1XDT R;  1MOX C;  1P0S L;  4ZXY L;  3FCS B;  3M36 L;  5IKR A;  2P3F N;  4X8T L;  3N8W A;  3ASI A;  1G1T A;  2J94 B;  2MGR A;  3FFG L;  3GIS X;  3N8Z A;  3SW2 A;  1HZ8 A;  5JVY A;  1LPZ A;  2VWN L;  2W2Q E;  3F6U L;  1UZJ A;  4RRX A;  3M37 L;  4D0E A;  4YT7 L;  1IQN L;  1NFU B;  1IQI L;  2P95 L;  1FSB A;  2J38 B;  3V65 B;  1V3X B;  2XBV L;  1IVO C;  1KIG L;  3C9A C;  2PHB B;  3MDL A;  2WPH E;  2J4I B;  2Y5G L;  1ATE A;  1HRF A;  5KN5 C;  3KQC L;  1ZAQ A;  1EPJ A;  1LK9 A;  3LN1 A;  2YGP A;  3OLU A;  1I0U A;  2TGF A;  2WPI E;  1KSN B;  4COX A;  3BT2 A;  2ADX A;  1HAF A;  4LMF A;  1EZQ B;  4JZF L;  2HOR A;  2WPK E;  1UZP A;  2D1J B;  2H9E C;  1XKA L;  1IQJ L;  1U8C B;  1G1Q A;  4MMX B;  1G2M B;  1PFX L;  2BZ6 L;  3QH0 A;  1TLE A;  2WFX B;  3S6X A;  2BMG A;  1X7A L;  1P9J A;  4D0F A;  2Q1J B;  3N8X A;  4PH9 A;  1FAK L;  2BO2 A;  4O1Z A;  4YT6 L;  5JB9 E;  2FLG A;  1EGF A;  4CSY A;  2EI6 B;  1EQG A;  3Q3K B;  3SOQ A;  1N1I A;  1CVW L;  2W86 A;  4XL1 A;  2GD4 A;  2F9B L;  2BSF A;  2P28 B;  1JBU L;  1F7E A;  1V1I A;  3HO3 A;  3RR3 A;  2FZZ L;  2W2N E;  4ISI L;  4RRZ A;  4TGF A;  1FF7 A;  4AQT A;  3Q7D A;  1PRH A;  4BXW A;  1LMJ A;  1KLO A;  2PR3 B; 
#chains in the Genus database with same CATH homology
 1NFX B;  4Y7A B;  2BQW A;  3CS7 L;  1TOZ A;  1FE2 A;  1O5D L;  1HJ7 A;  4D90 A;  3NTB A;  1Z6E L;  3HO4 A;  1UZQ A;  3HS6 A;  1IQE L;  2EI7 B;  2W2P E;  3SOB B;  3IJE B;  3FBY A;  1YUK B;  1IGX A;  2Y82 B;  2XC0 L;  2MGP A;  4RS0 A;  2JKH L;  1FAX L;  2K2T A;  1DX5 I;  3TK6 B;  2MHP A;  1EBV A;  5CKQ A;  1G2L B;  3TK5 B;  1NT0 A;  3TZI A;  2VVU L;  2BOX A;  2P94 L;  3MQE A;  1K36 A;  4BDW A;  1YUG A;  2WPM E;  4X8U L;  1HAE A;  2WZP P;  4E1G A;  5JBB E;  1APO A;  4MMY B;  1JV2 B;  5F1A A;  2Y5F L;  4NG9 L;  1QFK L;  1A3P A;  1G1S A;  1ATD A;  3K9X A;  3NT1 A;  1URK A;  1CQE A;  1IQM L;  1EPI A;  2P16 L;  4Z6A L;  5JVZ A;  1WU1 B;  3EGF A;  1IJQ A;  1HX2 A;  2G00 L;  4OTY A;  4Y76 B;  1LQD A;  1IQF L;  2Y80 B;  4Y71 B;  1YGC L;  1G1R A;  1K37 A;  3GCX E;  3HPT A;  3TGF A;  5CKN A;  3LAQ A;  1B9W A;  3LC5 B;  3ELA L;  4JZD L;  5JBA E;  3KRK A;  1CVU A;  1XKB A;  1FFM A;  1SZB A;  2RHP A;  5JW1 A;  1EAI C;  2J34 B;  2AYL A;  3NTG A;  1COU A;  2DDU A;  1HT8 A;  4Y6D B;  2I9B A;  2BQ7 A;  2FD6 A;  1ATB A;  3TH3 L;  2BQ6 A;  2UWL B;  4M11 A;  1EMN A;  3BT1 A;  3N8V A;  2B7D L;  2WPJ E;  1YUF A;  1C5M F;  2I9A A;  2W3I B;  1F0S B;  4G1M B;  1ATA A;  5CKM A;  5E8D A;  1DQB A;  1DDX A;  2J95 B;  4BTU A;  5I46 L;  4A94 C;  1DVA L;  1CEJ A;  4ZH8 B;  1EPH A;  4NA9 L;  4BDX A;  1UZK A;  3ZYG A;  1MQ5 L;  1DIY A;  3ENS A;  2VJ3 A;  3ZYJ B;  1BF9 A;  4CUE A;  3R05 A;  3P5B L;  2YGO A;  1IQH L;  1PTH A;  2RNL A;  2XC4 L;  1KLJ L;  2WG4 B;  1CX2 A;  5K0H B;  5EGM B;  5FDQ A;  2RA0 L;  3KQB L;  4JZE L;  2KNI A;  4NGA L;  2FLB L;  2VWM K;  2CJI B;  4M10 A;  6COX A;  4CUD A;  4XLW A;  2WFT A;  4ZXX L;  1J9C L;  4BTI A;  2BOH A;  1EPG A;  4ISH L;  1L5G B;  3LTG D;  2P3T A;  4O02 B;  3H5C B;  4RRY A;  2BOK L;  1IP0 A;  1NQL B;  3GCW E;  5JBC E;  1WHF A;  1OB1 C;  1HRE A;  1F0R B;  5CIS A;  2P3F L;  1F7M A;  1IOX A;  2J2U B;  4RUT A;  2BOU A;  3LC3 B;  1IOE L;  4ZAE B;  4MMZ B;  1IQL L;  5JB8 E;  2KL7 A;  4Z0L A;  5COX A;  5L2Z L;  5F19 A;  1W7X L;  3KQE L;  3KK6 A;  1RFN B;  2KB9 A;  2XBX L;  1N7D A;  1NFY B;  5L30 L;  2WG3 C;  2Y7Z B;  1IQK L;  1M1X B;  5IKQ A;  1Z6C A;  2PUQ L;  1XFE A;  5IKT A;  2OYU P;  3POY A;  2K2S B;  1HCG B;  4FM5 A;  3LN0 A;  1IGZ A;  2EI8 B;  4BTT A;  2P26 A;  2YGQ A;  3SOV A;  3DEM A;  3HO5 A;  2WYG B;  2WYJ B;  1GK5 A;  1FJS L;  1EMO A;  1YO8 A;  2XC5 L;  3CA7 A;  3CFW A;  1PGE A;  3PGH A;  3F1S B;  4Y7B B;  3N8W B;  5KIR A;  3N8Y A;  2UWO B;  3LIW B;  2VWO L;  2Y38 A;  2FLR L;  3HS7 A;  1MQ6 L;  2Y5H L;  1WHE A;  4X8S L;  3KL6 B;  1TPG A;  4XBM A;  3U73 A;  4A7I A;  5IKV A;  1PXX A;  1HT5 A;  3OLT A;  2XBW L;  3QMO A;  4JYU L;  2W3K B;  1IQG L;  4X8V L;  2WPL E;  1AUT L;  1JL9 A;  1LPK A;  3QCW A;  1EQH A;  2VVV L;  1W8B L;  3KCG L;  2P3U A;  2H9E L;  4YZU B;  4ZHA B;  1KLI L;  3TBD A;  2W2O E;  4LOR A;  4OTJ A;  3NJP C;  1NFW B;  1CCV A;  2P93 L;  4RRW A;  2M74 A;  4C16 A;  3CEN L;  3U7U G;  2VH6 B;  1APQ A;  2W26 B;  3IIT B;  2VH0 B;  1LPG A;  2NPR A;  2VVC K;  3KQD L;  1ADX A;  2XBY L;  3BPS E;  3V64 C;  2VWL L;  3ZYI B;  1NZI A;  4JYV L;  3HS5 A;  1LMM A;  2Y7X B;  2KV4 A;  2UWP B;  3N8Y B;  4CUF A;  1NPE B;  4Z0K B;  5L2Y L;  1CCF A;  3LTF B;  2OYE P;  1Q4G A;  2W2M E;  4BXS A;  1L3Y A;  2Y81 B;  1U67 A;  4Y79 B;  1XDT R;  1MOX C;  1P0S L;  4ZXY L;  3FCS B;  3M36 L;  5IKR A;  2P3F N;  4X8T L;  3N8W A;  3ASI A;  1G1T A;  2J94 B;  2MGR A;  3FFG L;  3GIS X;  3N8Z A;  3SW2 A;  1HZ8 A;  5JVY A;  1LPZ A;  2VWN L;  2W2Q E;  3F6U L;  1UZJ A;  4RRX A;  3M37 L;  4D0E A;  4YT7 L;  1IQN L;  1NFU B;  1IQI L;  2P95 L;  1FSB A;  2J38 B;  3V65 B;  1V3X B;  2XBV L;  1IVO C;  1KIG L;  3C9A C;  2PHB B;  3MDL A;  2WPH E;  2J4I B;  2Y5G L;  1ATE A;  1HRF A;  5KN5 C;  3KQC L;  1ZAQ A;  1EPJ A;  3LN1 A;  2YGP A;  3OLU A;  1I0U A;  2TGF A;  2WPI E;  1KSN B;  4COX A;  3BT2 A;  2ADX A;  1HAF A;  4LMF A;  1EZQ B;  4JZF L;  2WPK E;  1UZP A;  2D1J B;  2H9E C;  1XKA L;  1IQJ L;  1U8C B;  1G1Q A;  4MMX B;  1G2M B;  1PFX L;  2BZ6 L;  3QH0 A;  1TLE A;  2WFX B;  3S6X A;  2BMG A;  1X7A L;  1P9J A;  4D0F A;  2Q1J B;  3N8X A;  4PH9 A;  1FAK L;  2BO2 A;  4O1Z A;  4YT6 L;  5JB9 E;  2FLG A;  1EGF A;  4CSY A;  2EI6 B;  1EQG A;  3Q3K B;  3SOQ A;  1N1I A;  1CVW L;  2W86 A;  4XL1 A;  2GD4 A;  2F9B L;  2P28 B;  1JBU L;  1F7E A;  3HO3 A;  3RR3 A;  2FZZ L;  2W2N E;  4ISI L;  4RRZ A;  4TGF A;  1FF7 A;  4AQT A;  3Q7D A;  1PRH A;  4BXW A;  1LMJ A;  1KLO A;  2PR3 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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