3GCXE

Pcsk9:egfa (ph 7.4)
Total Genus 7
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
41
structure length
41
Chain Sequence
MGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Antagonism of Secreted PCSK9 Increases Low Density Lipoprotein Receptor Expression in HepG2 Cells.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Proprotein convertase subtilisin/kexin type 9
total genus 7
structure length 41
sequence length 41
ec nomenclature
pdb deposition date 2009-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF12662 cEGF Complement Clr-like EGF-like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3gcxE00
3LC3B 2GD4A 5JB9E 2W2PE 2Y7XB 1C5MF 1CCVA 2Y5GL 1ZAQA 5KIRA 4ZXYL 1KLJL 1EPJA 2VWLL 3HO3A 3GCWE 1IQEL 4Y7AB 3KQEL 3TBDA 2ADXA 2BQ6A 4BDXA 1KLOA 1IQFL 1XKBA 2XBVL 4RRZA 1KLIL 1BF9A 1MQ6L 2P3UA 3KQDL 4D0FA 1F0RB 4M11A 2P28B 4MMYB 5IKRA 1EMNA 2W86A 3KL6B 4PH9A 3H5CB 1U8CB 4CUFA 1WHFA 4BXWA 2UWLB 3RR3A 1HT8A 2J94B 1EMOA 2CJIB 3SOQA 4CUEA 2XC4L 1URKA 3NT1A 3EGFA 3HS7A 1IQML 4XLWA 1FAKL 2MGRA 2XBYL 3FFGL 4RUTA 3POYA 3LC5B 3F1SB 3LN1A 1WHEA 4D0EA 3ENSA 5COXA 1LMJA 1IQIL 1FJSL 3P5BL 3TK6B 2J38B 1F0SB 4BTIA 4M10A 3ZYIB 2MGPA 3N8XA 3SOVA 1AUTL 1IQLL 2EI7B 3FCSB 5JVZA 1YUGA 2W2ME 4A7IA 2FLGA 3KCGL 5L30L 1HRFA 1EQHA 1UZJA 4RS0A 1FSBA 2VJ3A 2FLBL 4OTYA 3LN0A 4MMZB 2WYGB 2Y7ZB 2KL7A 4X8SL 2W3KB 1EQGA 1LPKA 2WG4B 2J4IB 4O1ZA 1Q4GA 4X8TL 2Y5FL 3OLTA 3IITB 1FFMA 3BT2A 4JZDL 2PHBB 2Y81B 3BPSE 3GISX 4Z6AL 3KQCL 1XKAL 3U73A 2VH6B 5CKNA 4D90A 3K9XA 1TPGA 1DDXA 4LORA 2P3FL 1EPIA 3HO5A 2BQ7A 3U7UG 1PXXA 1L5GB 1NT0A 2W2QE 4C16A 1NQLB 2FD6A 5JBCE 1DVAL 3HS6A 5F19A 2I9AA 1SZBA 3ASIA 1YGCL 2W26B 2Y38A 1XDTR 1A3PA 1NFYB 3KRKA 1HZ8A 2J2UB 3ZYJB 1L3YA 2VVUL 4O02B 1G2MB 1G1TA 5IKTA 4Z0LA 2W2NE 1KSNB 2W2OE 1HAEA 4YZUB 1EPHA 1NFUB 1JV2B 3SW2A 3SOBB 1G1QA 1IOEL 2EI6B 2Y80B 1JL9A 2B7DL 1IJQA 1DX5I 4BXSA 1X7AL 2MHPA 4CSYA 5JB8E 5I46L 2JKHL 3CENL 3M37L 5L2YL 2VWMK 1G1SA 3NTGA 4Y7BB 1CVWL 3IJEB 1NPEB 3CS7L 5JW1A 1QFKL 2YGPA 6COXA 1ATAA 1CEJA 2D1JB 2RHPA 4RRWA 1N1IA 4AQTA 2P26A 1J9CL 2VVCK 4YT6L 1LQDA 1MOXC 3HS5A 2WFTA 4Y76B 4ZAEB 3MDLA 4X8VL 1PFXL 1FF7A 3TGFA 2UWOB 1IGZA 3HPTA 2J95B 4COXA 3R05A 2OYEP 3DEMA 2K2SB 2UWPB 5JBAE 4JYVL 4JZEL 1IOXA 2WFXB 1CX2A 1W7XL 1ATDA 1APOA 1LPZA 1JBUL 3C9AC 3N8YB 1IQKL 1WU1B 1TOZA 5F1AA 3LIWB 5L2ZL 1F7MA 4Z0KB 2NPRA 1W8BL 3ZYGA 3V65B 2P3FN 2YGOA 1UZPA 1ADXA 1IQJL 1IQGL 4ZHAB 2BZ6L 4XL1A 2VWOL 3OLUA 2PUQL 4JZFL 2TGFA 2G00L 3NJPC 3M36L 3PGHA 5K0HB 4TGFA 4YT7L 1HAFA 2OYUP 3KQBL 4RRXA 1IQHL 3QCWA 2Y5HL 4NG9L 1NZIA 2WPHE 1RFNB 2XBXL 1LPGA 3N8ZA 1KIGL 3F6UL 2WPIE 1IP0A 1ATEA 1Z6CA 2PR3B 4LMFA 3MQEA 3N8YA 1UZKA 2BOKL 1P0SL 1EGFA 2WG3C 2M74A 3LTFB 1IQNL 2XC5L 1NFXB 3KK6A 2AYLA 3V64C 2BOUA 1HREA 4MMXB 1IVOC 4OTJA 5E8DA 3ELAL 1B9WA 4X8UL 1YUFA 2P94L 5KN5C 4ISHL 2KB9A 4FM5A 1HT5A 1G1RA 3N8WB 2XBWL 3Q3KB 4ZH8B 1PGEA 2I9BA 2WPJE 2RNLA 1U67A 1CVUA 1F7EA 5IKQA 3Q7DA 1UZQA 2H9EL 4ISIL 2WPME 1NFWB 4RRYA 5CISA 1V3XB 3TZIA 2DDUA 3LTGD 2RA0L 3NTBA 4BTUA 2P16L 1CCFA 1PRHA 2FZZL 1FE2A 3QH0A 1YO8A 1TLEA 1DQBA 3GCXE 3CFWA 3LAQA 5JVYA 1P9JA 1IGXA 3BT1A 1Z6EL 4Y79B 2WPKE 1M1XB 1K37A 2BOXA 1I0UA 1OB1C 1G2LB 5JBBE 4ZXXL 1APQA 3FBYA 3N8WA 5EGMB 1YUKB 3N8VA 2W3IB 2WYJB 4CUDA 5CKQA 2P3TA 2BMGA 2WPLE 1MQ5L 2J34B 4NGAL 2BOHA 1EPGA 2K2TA 2KV4A 4Y71B 2EI8B 1ATBA 1HJ7A 4NA9L 4BDWA 2VH0B 1HX2A 2F9BL 1HCGB 2BO2A 2P93L 1GK5A 4G1MB 4BTTA 4Y6DB 1EAIC 4XBMA 2VVVL 2VWNL 2XC0L 2FLRL 1K36A 1PTHA 2BQWA 1FAXL 5FDQA 1EBVA 1CQEA 1COUA 3TK5B 1DIYA 2Q1JB 2P95L 4E1GA 1N7DA 2Y82B 3CA7A 5CKMA 5IKVA 3HO4A 1O5DL 1EZQB 1XFEA 3TH3L 4JYUL 3QMOA
chains in the Genus database with same CATH superfamily
3LC3B 2GD4A 5JB9E 2W2PE 2Y7XB 1C5MF 2BT7A 1CCVA 2Y5GL 1ZAQA 5KIRA 4ZXYL 1KLJL 1EPJA 2VWLL 3HO3A 2H9EC 3GCWE 1IQEL 4Y7AB 3KQEL 3TBDA 2ADXA 2BQ6A 4BDXA 1KLOA 1IQFL 1XKBA 2XBVL 4RRZA 1KLIL 1BF9A 1MQ6L 2P3UA 3KQDL 4D0FA 1F0RB 4M11A 2P28B 4MMYB 5IKRA 1EMNA 2W86A 3KL6B 4PH9A 3H5CB 2WZPP 1U8CB 4CUFA 1WHFA 4BXWA 2UWLB 3RR3A 1HT8A 2J94B 1EMOA 2CJIB 3SOQA 4CUEA 2XC4L 1URKA 3NT1A 3EGFA 3HS7A 1IQML 4XLWA 1FAKL 2MGRA 2XBYL 3FFGL 4RUTA 3POYA 3LC5B 3F1SB 3LN1A 1WHEA 4D0EA 3ENSA 5COXA 1LMJA 1IQIL 1FJSL 3P5BL 3TK6B 2J38B 1F0SB 4BTIA 4M10A 3ZYIB 2MGPA 3N8XA 3SOVA 1AUTL 1IQLL 2EI7B 3FCSB 5JVZA 1YUGA 2W2ME 4A7IA 2FLGA 3KCGL 5L30L 1HRFA 1EQHA 1UZJA 4RS0A 1FSBA 2VJ3A 2FLBL 4OTYA 3LN0A 4MMZB 2WYGB 2Y7ZB 2KL7A 4X8SL 2W3KB 1EQGA 1LPKA 2WG4B 2J4IB 4O1ZA 1Q4GA 4X8TL 2Y5FL 3OLTA 3IITB 1FFMA 3BT2A 2HOXA 4JZDL 2PHBB 2Y81B 3BPSE 3GISX 4Z6AL 3KQCL 1XKAL 3U73A 2VH6B 5CKNA 4D90A 3K9XA 1TPGA 1DDXA 4LORA 2P3FL 1EPIA 3HO5A 2BQ7A 3U7UG 1PXXA 4GU3A 1L5GB 1NT0A 2W2QE 4C16A 1NQLB 2FD6A 5JBCE 1DVAL 3HS6A 5F19A 2I9AA 1SZBA 3ASIA 1YGCL 2W26B 2Y38A 1XDTR 1A3PA 1NFYB 3KRKA 1HZ8A 2J2UB 3ZYJB 1L3YA 2VVUL 4O02B 1G2MB 1G1TA 5IKTA 1QIUA 4Z0LA 1LK9A 2W2NE 1KSNB 2W2OE 1HAEA 4YZUB 1EPHA 1NFUB 1JV2B 3SW2A 3SOBB 1G1QA 1IOEL 2EI6B 2Y80B 1JL9A 2B7DL 1IJQA 1DX5I 4BXSA 1X7AL 2MHPA 4CSYA 5JB8E 5I46L 2VRSA 2JKHL 3CENL 2YGQA 3M37L 1V1IA 5L2YL 2VWMK 1G1SA 3NTGA 4Y7BB 1CVWL 3IJEB 1NPEB 3CS7L 5JW1A 1QFKL 2YGPA 6COXA 1ATAA 1CEJA 2D1JB 2RHPA 4RRWA 1N1IA 4AQTA 2P26A 1J9CL 2VVCK 4YT6L 1LQDA 1MOXC 3HS5A 2WFTA 4Y76B 4ZAEB 3MDLA 4X8VL 1PFXL 1FF7A 4GU4A 3TGFA 2UWOB 1IGZA 3HPTA 2J95B 4COXA 3R05A 2OYEP 3DEMA 2K2SB 2UWPB 5JBAE 4JYVL 4JZEL 2HORA 1IOXA 3S6XA 2WFXB 1CX2A 1W7XL 2JJLA 1ATDA 1APOA 1LPZA 1JBUL 3C9AC 3N8YB 1IQKL 1WU1B 1TOZA 5F1AA 3LIWB 5L2ZL 1F7MA 4Z0KB 2NPRA 1W8BL 3ZYGA 3V65B 2P3FN 2YGOA 1UZPA 2BT8A 1ADXA 1IQJL 1IQGL 4ZHAB 2BZ6L 4XL1A 2VWOL 3OLUA 4A94C 2PUQL 4JZFL 2TGFA 2G00L 3NJPC 3M36L 3PGHA 5K0HB 4TGFA 4YT7L 1HAFA 2OYUP 2KNIA 3KQBL 4RRXA 1IQHL 3QCWA 2Y5HL 4NG9L 1NZIA 2WPHE 1RFNB 2XBXL 1LPGA 2BSFA 3N8ZA 1KIGL 3F6UL 2WPIE 1IP0A 1ATEA 1Z6CA 2PR3B 4LMFA 3MQEA 3N8YA 1UZKA 2BOKL 1P0SL 1EGFA 2WG3C 2M74A 3LTFB 1IQNL 2XC5L 1NFXB 3KK6A 2AYLA 3V64C 2BOUA 1HREA 4MMXB 1IVOC 4OTJA 5E8DA 3ELAL 1B9WA 4X8UL 1YUFA 2P94L 5KN5C 4ISHL 2KB9A 4FM5A 1HT5A 1G1RA 3N8WB 2XBWL 3Q3KB 4ZH8B 1PGEA 2I9BA 2WPJE 2RNLA 1U67A 1CVUA 1F7EA 5IKQA 3Q7DA 1UZQA 2H9EL 4ISIL 2WPME 1NFWB 4RRYA 5CISA 1V3XB 3TZIA 2DDUA 3LTGD 2RA0L 3NTBA 4BTUA 2P16L 1CCFA 1PRHA 2FZZL 1FE2A 3QH0A 1YO8A 1TLEA 1DQBA 3GCXE 3CFWA 3LAQA 5JVYA 1P9JA 1IGXA 3BT1A 1Z6EL 4Y79B 2WPKE 1M1XB 1K37A 2BOXA 1I0UA 1OB1C 1G2LB 5JBBE 4ZXXL 1APQA 3FBYA 3N8WA 5EGMB 1YUKB 3N8VA 1V1HA 2W3IB 2WYJB 4CUDA 5CKQA 2P3TA 2BMGA 2WPLE 1MQ5L 2J34B 4NGAL 2BOHA 1EPGA 2K2TA 2KV4A 4Y71B 2EI8B 1ATBA 1HJ7A 4NA9L 4BDWA 2VH0B 1HX2A 2F9BL 1LMMA 1HCGB 2BO2A 2P93L 1GK5A 4G1MB 4BTTA 4Y6DB 1EAIC 4XBMA 2VVVL 2VWNL 2XC0L 2FLRL 1KKEA 1K36A 1PTHA 2BQWA 1FAXL 5FDQA 1EBVA 1CQEA 1COUA 3TK5B 1DIYA 2Q1JB 2P95L 4E1GA 1N7DA 2Y82B 3CA7A 5CKMA 5IKVA 3HO4A 1O5DL 1EZQB 1XFEA 3TH3L 4JYUL 3QMOA
chains in the Genus database with same CATH topology
3LC3B 2GD4A 5JB9E 2W2PE 2Y7XB 1C5MF 1CCVA 2Y5GL 1ZAQA 5KIRA 4ZXYL 1KLJL 1EPJA 2VWLL 3HO3A 2H9EC 3GCWE 1IQEL 4Y7AB 3KQEL 3TBDA 2ADXA 2BQ6A 4BDXA 1KLOA 1IQFL 1XKBA 2XBVL 4RRZA 1KLIL 1BF9A 1MQ6L 2P3UA 3KQDL 4D0FA 1F0RB 4M11A 2P28B 4MMYB 5IKRA 1EMNA 2W86A 3KL6B 4PH9A 3H5CB 2WZPP 1U8CB 4CUFA 1WHFA 4BXWA 2UWLB 3RR3A 1HT8A 2J94B 1EMOA 2CJIB 3SOQA 4CUEA 2XC4L 1URKA 3NT1A 3EGFA 3HS7A 1IQML 4XLWA 1FAKL 2MGRA 2XBYL 3FFGL 4RUTA 3POYA 3LC5B 3F1SB 3LN1A 1WHEA 4D0EA 3ENSA 5COXA 1LMJA 1IQIL 1FJSL 3P5BL 3TK6B 2J38B 1F0SB 4BTIA 4M10A 3ZYIB 2MGPA 3N8XA 3SOVA 1AUTL 1IQLL 2EI7B 3FCSB 5JVZA 1YUGA 2W2ME 4A7IA 2FLGA 3KCGL 5L30L 1HRFA 1EQHA 1UZJA 4RS0A 1FSBA 2VJ3A 2FLBL 4OTYA 3LN0A 4MMZB 2WYGB 2Y7ZB 2KL7A 4X8SL 2W3KB 1EQGA 1LPKA 2WG4B 2J4IB 4O1ZA 1Q4GA 4X8TL 2Y5FL 3OLTA 3IITB 1FFMA 3BT2A 4JZDL 2PHBB 2Y81B 3BPSE 3GISX 4Z6AL 3KQCL 1XKAL 3U73A 2VH6B 5CKNA 4D90A 3K9XA 1TPGA 1DDXA 4LORA 2P3FL 1EPIA 3HO5A 2BQ7A 3U7UG 1PXXA 1L5GB 1NT0A 2W2QE 4C16A 1NQLB 2FD6A 5JBCE 1DVAL 3HS6A 5F19A 2I9AA 1SZBA 3ASIA 1YGCL 2W26B 2Y38A 1XDTR 1A3PA 1NFYB 3KRKA 1HZ8A 2J2UB 3ZYJB 1L3YA 2VVUL 4O02B 1G2MB 1G1TA 5IKTA 4Z0LA 2W2NE 1KSNB 2W2OE 1HAEA 4YZUB 1EPHA 1NFUB 1JV2B 3SW2A 3SOBB 1G1QA 1IOEL 2EI6B 2Y80B 1JL9A 2B7DL 1IJQA 1DX5I 4BXSA 1X7AL 2MHPA 4CSYA 5JB8E 5I46L 2JKHL 3CENL 2YGQA 3M37L 5L2YL 2VWMK 1G1SA 3NTGA 4Y7BB 1CVWL 3IJEB 1NPEB 3CS7L 5JW1A 1QFKL 2YGPA 6COXA 1ATAA 1CEJA 2D1JB 2RHPA 4RRWA 1N1IA 4AQTA 2P26A 1J9CL 2VVCK 4YT6L 1LQDA 1MOXC 3HS5A 2WFTA 4Y76B 4ZAEB 3MDLA 4X8VL 1PFXL 1FF7A 3TGFA 2UWOB 1IGZA 3HPTA 2J95B 4COXA 3R05A 2OYEP 3DEMA 2K2SB 2UWPB 5JBAE 4JYVL 4JZEL 1IOXA 3S6XA 2WFXB 1CX2A 1W7XL 1ATDA 1APOA 1LPZA 1JBUL 3C9AC 3N8YB 1IQKL 1WU1B 1TOZA 5F1AA 3LIWB 5L2ZL 1F7MA 4Z0KB 2NPRA 1W8BL 3ZYGA 3V65B 2P3FN 2YGOA 1UZPA 1ADXA 1IQJL 1IQGL 4ZHAB 2BZ6L 4XL1A 2VWOL 3OLUA 4A94C 2PUQL 4JZFL 2TGFA 2G00L 3NJPC 3M36L 3PGHA 5K0HB 4TGFA 4YT7L 1HAFA 2OYUP 2KNIA 3KQBL 4RRXA 1IQHL 3QCWA 2Y5HL 4NG9L 1NZIA 2WPHE 1RFNB 2XBXL 1LPGA 3N8ZA 1KIGL 3F6UL 2WPIE 1IP0A 1ATEA 1Z6CA 2PR3B 4LMFA 3MQEA 3N8YA 1UZKA 2BOKL 1P0SL 1EGFA 2WG3C 2M74A 3LTFB 1IQNL 2XC5L 1NFXB 3KK6A 2AYLA 3V64C 2BOUA 1HREA 4MMXB 1IVOC 4OTJA 5E8DA 3ELAL 1B9WA 4X8UL 1YUFA 2P94L 5KN5C 4ISHL 2KB9A 4FM5A 1HT5A 1G1RA 3N8WB 2XBWL 3Q3KB 4ZH8B 1PGEA 2I9BA 2WPJE 2RNLA 1U67A 1CVUA 1F7EA 5IKQA 3Q7DA 1UZQA 2H9EL 4ISIL 2WPME 1NFWB 4RRYA 5CISA 1V3XB 3TZIA 2DDUA 3LTGD 2RA0L 3NTBA 4BTUA 2P16L 1CCFA 1PRHA 2FZZL 1FE2A 3QH0A 1YO8A 1TLEA 1DQBA 3GCXE 3CFWA 3LAQA 5JVYA 1P9JA 1IGXA 3BT1A 1Z6EL 4Y79B 2WPKE 1M1XB 1K37A 2BOXA 1I0UA 1OB1C 1G2LB 5JBBE 4ZXXL 1APQA 3FBYA 3N8WA 5EGMB 1YUKB 3N8VA 2W3IB 2WYJB 4CUDA 5CKQA 2P3TA 2BMGA 2WPLE 1MQ5L 2J34B 4NGAL 2BOHA 1EPGA 2K2TA 2KV4A 4Y71B 2EI8B 1ATBA 1HJ7A 4NA9L 4BDWA 2VH0B 1HX2A 2F9BL 1LMMA 1HCGB 2BO2A 2P93L 1GK5A 4G1MB 4BTTA 4Y6DB 1EAIC 4XBMA 2VVVL 2VWNL 2XC0L 2FLRL 1K36A 1PTHA 2BQWA 1FAXL 5FDQA 1EBVA 1CQEA 1COUA 3TK5B 1DIYA 2Q1JB 2P95L 4E1GA 1N7DA 2Y82B 3CA7A 5CKMA 5IKVA 3HO4A 1O5DL 1EZQB 1XFEA 3TH3L 4JYUL 3QMOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LC3 B;  2GD4 A;  5JB9 E;  2W2P E;  2Y7X B;  1C5M F;  1CCV A;  2Y5G L;  1ZAQ A;  5KIR A;  4ZXY L;  1KLJ L;  1EPJ A;  2VWL L;  3HO3 A;  3GCW E;  1IQE L;  4Y7A B;  3KQE L;  3TBD A;  2ADX A;  2BQ6 A;  4BDX A;  1KLO A;  1IQF L;  1XKB A;  2XBV L;  4RRZ A;  1KLI L;  1BF9 A;  1MQ6 L;  2P3U A;  3KQD L;  4D0F A;  1F0R B;  4M11 A;  2P28 B;  4MMY B;  5IKR A;  1EMN A;  2W86 A;  3KL6 B;  4PH9 A;  3H5C B;  1U8C B;  4CUF A;  1WHF A;  4BXW A;  2UWL B;  3RR3 A;  1HT8 A;  2J94 B;  1EMO A;  2CJI B;  3SOQ A;  4CUE A;  2XC4 L;  1URK A;  3NT1 A;  3EGF A;  3HS7 A;  1IQM L;  4XLW A;  1FAK L;  2MGR A;  2XBY L;  3FFG L;  4RUT A;  3POY A;  3LC5 B;  3F1S B;  3LN1 A;  1WHE A;  4D0E A;  3ENS A;  5COX A;  1LMJ A;  1IQI L;  1FJS L;  3P5B L;  3TK6 B;  2J38 B;  1F0S B;  4BTI A;  4M10 A;  3ZYI B;  2MGP A;  3N8X A;  3SOV A;  1AUT L;  1IQL L;  2EI7 B;  3FCS B;  5JVZ A;  1YUG A;  2W2M E;  4A7I A;  2FLG A;  3KCG L;  5L30 L;  1HRF A;  1EQH A;  1UZJ A;  4RS0 A;  1FSB A;  2VJ3 A;  2FLB L;  4OTY A;  3LN0 A;  4MMZ B;  2WYG B;  2Y7Z B;  2KL7 A;  4X8S L;  2W3K B;  1EQG A;  1LPK A;  2WG4 B;  2J4I B;  4O1Z A;  1Q4G A;  4X8T L;  2Y5F L;  3OLT A;  3IIT B;  1FFM A;  3BT2 A;  4JZD L;  2PHB B;  2Y81 B;  3BPS E;  3GIS X;  4Z6A L;  3KQC L;  1XKA L;  3U73 A;  2VH6 B;  5CKN A;  4D90 A;  3K9X A;  1TPG A;  1DDX A;  4LOR A;  2P3F L;  1EPI A;  3HO5 A;  2BQ7 A;  3U7U G;  1PXX A;  1L5G B;  1NT0 A;  2W2Q E;  4C16 A;  1NQL B;  2FD6 A;  5JBC E;  1DVA L;  3HS6 A;  5F19 A;  2I9A A;  1SZB A;  3ASI A;  1YGC L;  2W26 B;  2Y38 A;  1XDT R;  1A3P A;  1NFY B;  3KRK A;  1HZ8 A;  2J2U B;  3ZYJ B;  1L3Y A;  2VVU L;  4O02 B;  1G2M B;  1G1T A;  5IKT A;  4Z0L A;  2W2N E;  1KSN B;  2W2O E;  1HAE A;  4YZU B;  1EPH A;  1NFU B;  1JV2 B;  3SW2 A;  3SOB B;  1G1Q A;  1IOE L;  2EI6 B;  2Y80 B;  1JL9 A;  2B7D L;  1IJQ A;  1DX5 I;  4BXS A;  1X7A L;  2MHP A;  4CSY A;  5JB8 E;  5I46 L;  2JKH L;  3CEN L;  3M37 L;  5L2Y L;  2VWM K;  1G1S A;  3NTG A;  4Y7B B;  1CVW L;  3IJE B;  1NPE B;  3CS7 L;  5JW1 A;  1QFK L;  2YGP A;  6COX A;  1ATA A;  1CEJ A;  2D1J B;  2RHP A;  4RRW A;  1N1I A;  4AQT A;  2P26 A;  1J9C L;  2VVC K;  4YT6 L;  1LQD A;  1MOX C;  3HS5 A;  2WFT A;  4Y76 B;  4ZAE B;  3MDL A;  4X8V L;  1PFX L;  1FF7 A;  3TGF A;  2UWO B;  1IGZ A;  3HPT A;  2J95 B;  4COX A;  3R05 A;  2OYE P;  3DEM A;  2K2S B;  2UWP B;  5JBA E;  4JYV L;  4JZE L;  1IOX A;  2WFX B;  1CX2 A;  1W7X L;  1ATD A;  1APO A;  1LPZ A;  1JBU L;  3C9A C;  3N8Y B;  1IQK L;  1WU1 B;  1TOZ A;  5F1A A;  3LIW B;  5L2Z L;  1F7M A;  4Z0K B;  2NPR A;  1W8B L;  3ZYG A;  3V65 B;  2P3F N;  2YGO A;  1UZP A;  1ADX A;  1IQJ L;  1IQG L;  4ZHA B;  2BZ6 L;  4XL1 A;  2VWO L;  3OLU A;  2PUQ L;  4JZF L;  2TGF A;  2G00 L;  3NJP C;  3M36 L;  3PGH A;  5K0H B;  4TGF A;  4YT7 L;  1HAF A;  2OYU P;  3KQB L;  4RRX A;  1IQH L;  3QCW A;  2Y5H L;  4NG9 L;  1NZI A;  2WPH E;  1RFN B;  2XBX L;  1LPG A;  3N8Z A;  1KIG L;  3F6U L;  2WPI E;  1IP0 A;  1ATE A;  1Z6C A;  2PR3 B;  4LMF A;  3MQE A;  3N8Y A;  1UZK A;  2BOK L;  1P0S L;  1EGF A;  2WG3 C;  2M74 A;  3LTF B;  1IQN L;  2XC5 L;  1NFX B;  3KK6 A;  2AYL A;  3V64 C;  2BOU A;  1HRE A;  4MMX B;  1IVO C;  4OTJ A;  5E8D A;  3ELA L;  1B9W A;  4X8U L;  1YUF A;  2P94 L;  5KN5 C;  4ISH L;  2KB9 A;  4FM5 A;  1HT5 A;  1G1R A;  3N8W B;  2XBW L;  3Q3K B;  4ZH8 B;  1PGE A;  2I9B A;  2WPJ E;  2RNL A;  1U67 A;  1CVU A;  1F7E A;  5IKQ A;  3Q7D A;  1UZQ A;  2H9E L;  4ISI L;  2WPM E;  1NFW B;  4RRY A;  5CIS A;  1V3X B;  3TZI A;  2DDU A;  3LTG D;  2RA0 L;  3NTB A;  4BTU A;  2P16 L;  1CCF A;  1PRH A;  2FZZ L;  1FE2 A;  3QH0 A;  1YO8 A;  1TLE A;  1DQB A;  3GCX E;  3CFW A;  3LAQ A;  5JVY A;  1P9J A;  1IGX A;  3BT1 A;  1Z6E L;  4Y79 B;  2WPK E;  1M1X B;  1K37 A;  2BOX A;  1I0U A;  1OB1 C;  1G2L B;  5JBB E;  4ZXX L;  1APQ A;  3FBY A;  3N8W A;  5EGM B;  1YUK B;  3N8V A;  2W3I B;  2WYJ B;  4CUD A;  5CKQ A;  2P3T A;  2BMG A;  2WPL E;  1MQ5 L;  2J34 B;  4NGA L;  2BOH A;  1EPG A;  2K2T A;  2KV4 A;  4Y71 B;  2EI8 B;  1ATB A;  1HJ7 A;  4NA9 L;  4BDW A;  2VH0 B;  1HX2 A;  2F9B L;  1HCG B;  2BO2 A;  2P93 L;  1GK5 A;  4G1M B;  4BTT A;  4Y6D B;  1EAI C;  4XBM A;  2VVV L;  2VWN L;  2XC0 L;  2FLR L;  1K36 A;  1PTH A;  2BQW A;  1FAX L;  5FDQ A;  1EBV A;  1CQE A;  1COU A;  3TK5 B;  1DIY A;  2Q1J B;  2P95 L;  4E1G A;  1N7D A;  2Y82 B;  3CA7 A;  5CKM A;  5IKV A;  3HO4 A;  1O5D L;  1EZQ B;  1XFE A;  3TH3 L;  4JYU L;  3QMO A; 
#chains in the Genus database with same CATH topology
 3LC3 B;  2GD4 A;  5JB9 E;  2W2P E;  2Y7X B;  1C5M F;  2BT7 A;  1CCV A;  2Y5G L;  1ZAQ A;  5KIR A;  4ZXY L;  1KLJ L;  1EPJ A;  2VWL L;  3HO3 A;  2H9E C;  3GCW E;  1IQE L;  4Y7A B;  3KQE L;  3TBD A;  2ADX A;  2BQ6 A;  4BDX A;  1KLO A;  1IQF L;  1XKB A;  2XBV L;  4RRZ A;  1KLI L;  1BF9 A;  1MQ6 L;  2P3U A;  3KQD L;  4D0F A;  1F0R B;  4M11 A;  2P28 B;  4MMY B;  5IKR A;  1EMN A;  2W86 A;  3KL6 B;  4PH9 A;  3H5C B;  2WZP P;  1U8C B;  4CUF A;  1WHF A;  4BXW A;  2UWL B;  3RR3 A;  1HT8 A;  2J94 B;  1EMO A;  2CJI B;  3SOQ A;  4CUE A;  2XC4 L;  1URK A;  3NT1 A;  3EGF A;  3HS7 A;  1IQM L;  4XLW A;  1FAK L;  2MGR A;  2XBY L;  3FFG L;  4RUT A;  3POY A;  3LC5 B;  3F1S B;  3LN1 A;  1WHE A;  4D0E A;  3ENS A;  5COX A;  1LMJ A;  1IQI L;  1FJS L;  3P5B L;  3TK6 B;  2J38 B;  1F0S B;  4BTI A;  4M10 A;  3ZYI B;  2MGP A;  3N8X A;  3SOV A;  1AUT L;  1IQL L;  2EI7 B;  3FCS B;  5JVZ A;  1YUG A;  2W2M E;  4A7I A;  2FLG A;  3KCG L;  5L30 L;  1HRF A;  1EQH A;  1UZJ A;  4RS0 A;  1FSB A;  2VJ3 A;  2FLB L;  4OTY A;  3LN0 A;  4MMZ B;  2WYG B;  2Y7Z B;  2KL7 A;  4X8S L;  2W3K B;  1EQG A;  1LPK A;  2WG4 B;  2J4I B;  4O1Z A;  1Q4G A;  4X8T L;  2Y5F L;  3OLT A;  3IIT B;  1FFM A;  3BT2 A;  2HOX A;  4JZD L;  2PHB B;  2Y81 B;  3BPS E;  3GIS X;  4Z6A L;  3KQC L;  1XKA L;  3U73 A;  2VH6 B;  5CKN A;  4D90 A;  3K9X A;  1TPG A;  1DDX A;  4LOR A;  2P3F L;  1EPI A;  3HO5 A;  2BQ7 A;  3U7U G;  1PXX A;  4GU3 A;  1L5G B;  1NT0 A;  2W2Q E;  4C16 A;  1NQL B;  2FD6 A;  5JBC E;  1DVA L;  3HS6 A;  5F19 A;  2I9A A;  1SZB A;  3ASI A;  1YGC L;  2W26 B;  2Y38 A;  1XDT R;  1A3P A;  1NFY B;  3KRK A;  1HZ8 A;  2J2U B;  3ZYJ B;  1L3Y A;  2VVU L;  4O02 B;  1G2M B;  1G1T A;  5IKT A;  1QIU A;  4Z0L A;  1LK9 A;  2W2N E;  1KSN B;  2W2O E;  1HAE A;  4YZU B;  1EPH A;  1NFU B;  1JV2 B;  3SW2 A;  3SOB B;  1G1Q A;  1IOE L;  2EI6 B;  2Y80 B;  1JL9 A;  2B7D L;  1IJQ A;  1DX5 I;  4BXS A;  1X7A L;  2MHP A;  4CSY A;  5JB8 E;  5I46 L;  2VRS A;  2JKH L;  3CEN L;  2YGQ A;  3M37 L;  1V1I A;  5L2Y L;  2VWM K;  1G1S A;  3NTG A;  4Y7B B;  1CVW L;  3IJE B;  1NPE B;  3CS7 L;  5JW1 A;  1QFK L;  2YGP A;  6COX A;  1ATA A;  1CEJ A;  2D1J B;  2RHP A;  4RRW A;  1N1I A;  4AQT A;  2P26 A;  1J9C L;  2VVC K;  4YT6 L;  1LQD A;  1MOX C;  3HS5 A;  2WFT A;  4Y76 B;  4ZAE B;  3MDL A;  4X8V L;  1PFX L;  1FF7 A;  4GU4 A;  3TGF A;  2UWO B;  1IGZ A;  3HPT A;  2J95 B;  4COX A;  3R05 A;  2OYE P;  3DEM A;  2K2S B;  2UWP B;  5JBA E;  4JYV L;  4JZE L;  2HOR A;  1IOX A;  3S6X A;  2WFX B;  1CX2 A;  1W7X L;  2JJL A;  1ATD A;  1APO A;  1LPZ A;  1JBU L;  3C9A C;  3N8Y B;  1IQK L;  1WU1 B;  1TOZ A;  5F1A A;  3LIW B;  5L2Z L;  1F7M A;  4Z0K B;  2NPR A;  1W8B L;  3ZYG A;  3V65 B;  2P3F N;  2YGO A;  1UZP A;  2BT8 A;  1ADX A;  1IQJ L;  1IQG L;  4ZHA B;  2BZ6 L;  4XL1 A;  2VWO L;  3OLU A;  4A94 C;  2PUQ L;  4JZF L;  2TGF A;  2G00 L;  3NJP C;  3M36 L;  3PGH A;  5K0H B;  4TGF A;  4YT7 L;  1HAF A;  2OYU P;  2KNI A;  3KQB L;  4RRX A;  1IQH L;  3QCW A;  2Y5H L;  4NG9 L;  1NZI A;  2WPH E;  1RFN B;  2XBX L;  1LPG A;  2BSF A;  3N8Z A;  1KIG L;  3F6U L;  2WPI E;  1IP0 A;  1ATE A;  1Z6C A;  2PR3 B;  4LMF A;  3MQE A;  3N8Y A;  1UZK A;  2BOK L;  1P0S L;  1EGF A;  2WG3 C;  2M74 A;  3LTF B;  1IQN L;  2XC5 L;  1NFX B;  3KK6 A;  2AYL A;  3V64 C;  2BOU A;  1HRE A;  4MMX B;  1IVO C;  4OTJ A;  5E8D A;  3ELA L;  1B9W A;  4X8U L;  1YUF A;  2P94 L;  5KN5 C;  4ISH L;  2KB9 A;  4FM5 A;  1HT5 A;  1G1R A;  3N8W B;  2XBW L;  3Q3K B;  4ZH8 B;  1PGE A;  2I9B A;  2WPJ E;  2RNL A;  1U67 A;  1CVU A;  1F7E A;  5IKQ A;  3Q7D A;  1UZQ A;  2H9E L;  4ISI L;  2WPM E;  1NFW B;  4RRY A;  5CIS A;  1V3X B;  3TZI A;  2DDU A;  3LTG D;  2RA0 L;  3NTB A;  4BTU A;  2P16 L;  1CCF A;  1PRH A;  2FZZ L;  1FE2 A;  3QH0 A;  1YO8 A;  1TLE A;  1DQB A;  3GCX E;  3CFW A;  3LAQ A;  5JVY A;  1P9J A;  1IGX A;  3BT1 A;  1Z6E L;  4Y79 B;  2WPK E;  1M1X B;  1K37 A;  2BOX A;  1I0U A;  1OB1 C;  1G2L B;  5JBB E;  4ZXX L;  1APQ A;  3FBY A;  3N8W A;  5EGM B;  1YUK B;  3N8V A;  1V1H A;  2W3I B;  2WYJ B;  4CUD A;  5CKQ A;  2P3T A;  2BMG A;  2WPL E;  1MQ5 L;  2J34 B;  4NGA L;  2BOH A;  1EPG A;  2K2T A;  2KV4 A;  4Y71 B;  2EI8 B;  1ATB A;  1HJ7 A;  4NA9 L;  4BDW A;  2VH0 B;  1HX2 A;  2F9B L;  1LMM A;  1HCG B;  2BO2 A;  2P93 L;  1GK5 A;  4G1M B;  4BTT A;  4Y6D B;  1EAI C;  4XBM A;  2VVV L;  2VWN L;  2XC0 L;  2FLR L;  1KKE A;  1K36 A;  1PTH A;  2BQW A;  1FAX L;  5FDQ A;  1EBV A;  1CQE A;  1COU A;  3TK5 B;  1DIY A;  2Q1J B;  2P95 L;  4E1G A;  1N7D A;  2Y82 B;  3CA7 A;  5CKM A;  5IKV A;  3HO4 A;  1O5D L;  1EZQ B;  1XFE A;  3TH3 L;  4JYU L;  3QMO A; 
#chains in the Genus database with same CATH homology
 3LC3 B;  2GD4 A;  5JB9 E;  2W2P E;  2Y7X B;  1C5M F;  1CCV A;  2Y5G L;  1ZAQ A;  5KIR A;  4ZXY L;  1KLJ L;  1EPJ A;  2VWL L;  3HO3 A;  2H9E C;  3GCW E;  1IQE L;  4Y7A B;  3KQE L;  3TBD A;  2ADX A;  2BQ6 A;  4BDX A;  1KLO A;  1IQF L;  1XKB A;  2XBV L;  4RRZ A;  1KLI L;  1BF9 A;  1MQ6 L;  2P3U A;  3KQD L;  4D0F A;  1F0R B;  4M11 A;  2P28 B;  4MMY B;  5IKR A;  1EMN A;  2W86 A;  3KL6 B;  4PH9 A;  3H5C B;  2WZP P;  1U8C B;  4CUF A;  1WHF A;  4BXW A;  2UWL B;  3RR3 A;  1HT8 A;  2J94 B;  1EMO A;  2CJI B;  3SOQ A;  4CUE A;  2XC4 L;  1URK A;  3NT1 A;  3EGF A;  3HS7 A;  1IQM L;  4XLW A;  1FAK L;  2MGR A;  2XBY L;  3FFG L;  4RUT A;  3POY A;  3LC5 B;  3F1S B;  3LN1 A;  1WHE A;  4D0E A;  3ENS A;  5COX A;  1LMJ A;  1IQI L;  1FJS L;  3P5B L;  3TK6 B;  2J38 B;  1F0S B;  4BTI A;  4M10 A;  3ZYI B;  2MGP A;  3N8X A;  3SOV A;  1AUT L;  1IQL L;  2EI7 B;  3FCS B;  5JVZ A;  1YUG A;  2W2M E;  4A7I A;  2FLG A;  3KCG L;  5L30 L;  1HRF A;  1EQH A;  1UZJ A;  4RS0 A;  1FSB A;  2VJ3 A;  2FLB L;  4OTY A;  3LN0 A;  4MMZ B;  2WYG B;  2Y7Z B;  2KL7 A;  4X8S L;  2W3K B;  1EQG A;  1LPK A;  2WG4 B;  2J4I B;  4O1Z A;  1Q4G A;  4X8T L;  2Y5F L;  3OLT A;  3IIT B;  1FFM A;  3BT2 A;  4JZD L;  2PHB B;  2Y81 B;  3BPS E;  3GIS X;  4Z6A L;  3KQC L;  1XKA L;  3U73 A;  2VH6 B;  5CKN A;  4D90 A;  3K9X A;  1TPG A;  1DDX A;  4LOR A;  2P3F L;  1EPI A;  3HO5 A;  2BQ7 A;  3U7U G;  1PXX A;  1L5G B;  1NT0 A;  2W2Q E;  4C16 A;  1NQL B;  2FD6 A;  5JBC E;  1DVA L;  3HS6 A;  5F19 A;  2I9A A;  1SZB A;  3ASI A;  1YGC L;  2W26 B;  2Y38 A;  1XDT R;  1A3P A;  1NFY B;  3KRK A;  1HZ8 A;  2J2U B;  3ZYJ B;  1L3Y A;  2VVU L;  4O02 B;  1G2M B;  1G1T A;  5IKT A;  4Z0L A;  2W2N E;  1KSN B;  2W2O E;  1HAE A;  4YZU B;  1EPH A;  1NFU B;  1JV2 B;  3SW2 A;  3SOB B;  1G1Q A;  1IOE L;  2EI6 B;  2Y80 B;  1JL9 A;  2B7D L;  1IJQ A;  1DX5 I;  4BXS A;  1X7A L;  2MHP A;  4CSY A;  5JB8 E;  5I46 L;  2JKH L;  3CEN L;  2YGQ A;  3M37 L;  5L2Y L;  2VWM K;  1G1S A;  3NTG A;  4Y7B B;  1CVW L;  3IJE B;  1NPE B;  3CS7 L;  5JW1 A;  1QFK L;  2YGP A;  6COX A;  1ATA A;  1CEJ A;  2D1J B;  2RHP A;  4RRW A;  1N1I A;  4AQT A;  2P26 A;  1J9C L;  2VVC K;  4YT6 L;  1LQD A;  1MOX C;  3HS5 A;  2WFT A;  4Y76 B;  4ZAE B;  3MDL A;  4X8V L;  1PFX L;  1FF7 A;  3TGF A;  2UWO B;  1IGZ A;  3HPT A;  2J95 B;  4COX A;  3R05 A;  2OYE P;  3DEM A;  2K2S B;  2UWP B;  5JBA E;  4JYV L;  4JZE L;  1IOX A;  3S6X A;  2WFX B;  1CX2 A;  1W7X L;  1ATD A;  1APO A;  1LPZ A;  1JBU L;  3C9A C;  3N8Y B;  1IQK L;  1WU1 B;  1TOZ A;  5F1A A;  3LIW B;  5L2Z L;  1F7M A;  4Z0K B;  2NPR A;  1W8B L;  3ZYG A;  3V65 B;  2P3F N;  2YGO A;  1UZP A;  1ADX A;  1IQJ L;  1IQG L;  4ZHA B;  2BZ6 L;  4XL1 A;  2VWO L;  3OLU A;  4A94 C;  2PUQ L;  4JZF L;  2TGF A;  2G00 L;  3NJP C;  3M36 L;  3PGH A;  5K0H B;  4TGF A;  4YT7 L;  1HAF A;  2OYU P;  2KNI A;  3KQB L;  4RRX A;  1IQH L;  3QCW A;  2Y5H L;  4NG9 L;  1NZI A;  2WPH E;  1RFN B;  2XBX L;  1LPG A;  3N8Z A;  1KIG L;  3F6U L;  2WPI E;  1IP0 A;  1ATE A;  1Z6C A;  2PR3 B;  4LMF A;  3MQE A;  3N8Y A;  1UZK A;  2BOK L;  1P0S L;  1EGF A;  2WG3 C;  2M74 A;  3LTF B;  1IQN L;  2XC5 L;  1NFX B;  3KK6 A;  2AYL A;  3V64 C;  2BOU A;  1HRE A;  4MMX B;  1IVO C;  4OTJ A;  5E8D A;  3ELA L;  1B9W A;  4X8U L;  1YUF A;  2P94 L;  5KN5 C;  4ISH L;  2KB9 A;  4FM5 A;  1HT5 A;  1G1R A;  3N8W B;  2XBW L;  3Q3K B;  4ZH8 B;  1PGE A;  2I9B A;  2WPJ E;  2RNL A;  1U67 A;  1CVU A;  1F7E A;  5IKQ A;  3Q7D A;  1UZQ A;  2H9E L;  4ISI L;  2WPM E;  1NFW B;  4RRY A;  5CIS A;  1V3X B;  3TZI A;  2DDU A;  3LTG D;  2RA0 L;  3NTB A;  4BTU A;  2P16 L;  1CCF A;  1PRH A;  2FZZ L;  1FE2 A;  3QH0 A;  1YO8 A;  1TLE A;  1DQB A;  3GCX E;  3CFW A;  3LAQ A;  5JVY A;  1P9J A;  1IGX A;  3BT1 A;  1Z6E L;  4Y79 B;  2WPK E;  1M1X B;  1K37 A;  2BOX A;  1I0U A;  1OB1 C;  1G2L B;  5JBB E;  4ZXX L;  1APQ A;  3FBY A;  3N8W A;  5EGM B;  1YUK B;  3N8V A;  2W3I B;  2WYJ B;  4CUD A;  5CKQ A;  2P3T A;  2BMG A;  2WPL E;  1MQ5 L;  2J34 B;  4NGA L;  2BOH A;  1EPG A;  2K2T A;  2KV4 A;  4Y71 B;  2EI8 B;  1ATB A;  1HJ7 A;  4NA9 L;  4BDW A;  2VH0 B;  1HX2 A;  2F9B L;  1LMM A;  1HCG B;  2BO2 A;  2P93 L;  1GK5 A;  4G1M B;  4BTT A;  4Y6D B;  1EAI C;  4XBM A;  2VVV L;  2VWN L;  2XC0 L;  2FLR L;  1K36 A;  1PTH A;  2BQW A;  1FAX L;  5FDQ A;  1EBV A;  1CQE A;  1COU A;  3TK5 B;  1DIY A;  2Q1J B;  2P95 L;  4E1G A;  1N7D A;  2Y82 B;  3CA7 A;  5CKM A;  5IKV A;  3HO4 A;  1O5D L;  1EZQ B;  1XFE A;  3TH3 L;  4JYU L;  3QMO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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