3GISX

Crystal structure of na-free thrombin in complex with thrombomodulin
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
115
structure length
113
Chain Sequence
DPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQLFCNQTACPADCDPNASCECPEGYILDDGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSALAGQIGTDCD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Molecular basis of thrombomodulin activation of slow thrombin
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords Prothrombin
total genus 15
structure length 113
sequence length 115
chains with identical sequence Y, Z
ec nomenclature
pdb deposition date 2009-03-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3gisX01
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3gisX03
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3gisX02
3HO3A 2BQ7A 1FJSL 2Y7XB 1JV2B 1KLIL 2FLGA 1EQHA 1HCGB 2VWMK 1JBUL 3GCWE 1HJ7A 4MMXB 2RA0L 2W3IB 2P3TA 3ELAL 1PFXL 1MQ6L 1A3PA 2UWOB 1PGEA 2P93L 2Y81B 1IQGL 1N7DA 2W2OE 3NT1A 4Y79B 2WFXB 3KCGL 1K37A 1HREA 3V64C 3LC3B 4ISIL 1KLJL 2WPME 3C9AC 1G2LB 3RR3A 1F7MA 1F0RB 2BOXA 1WU1B 1LQDA 2BOHA 2GD4A 2VH6B 3BT2A 5CISA 3TK6B 1J9CL 3GCXE 1EBVA 2P26A 1SZBA 5E8DA 4JZDL 4COXA 2VJ3A 1EPIA 1LPGA 3R05A 1IQKL 5JVYA 5L30L 1IOEL 2BOKL 4YT7L 1XKAL 2W2NE 2CJIB 4Y7BB 2BO2A 2WPLE 2Y5FL 3LN1A 2MHPA 2WPIE 5I46L 1B9WA 5IKTA 5L2ZL 3KL6B 3TBDA 4AQTA 4LORA 4ZHAB 3QH0A 4Z0LA 5IKRA 3M37L 3IJEB 2XBYL 2W26B 3LAQA 1FE2A 3OLTA 4G1MB 4Z6AL 1NFWB 1Z6EL 3ZYGA 3OLUA 2ADXA 3N8YA 1RFNB 4LMFA 3TZIA 4YT6L 4ISHL 4Y7AB 1Q4GA 5EGMB 1DQBA 1Z6CA 1K36A 5COXA 3CA7A 1HAFA 2XBWL 2KB9A 3MQEA 3DEMA 1L3YA 1G1SA 1HT8A 3LTFB 1HZ8A 1XFEA 3NTGA 1YUFA 1IGZA 1QFKL 3TK5B 3PGHA 1NPEB 2EI8B 1EPHA 4D0EA 4Y6DB 4C16A 3K9XA 2PUQL 3HO4A 1IP0A 1DIYA 3LTGD 5JB8E 1P9JA 5KIRA 1YUKB 4Y71B 2I9AA 2NPRA 2Y5GL 1V3XB 3NTBA 4PH9A 4BXSA 5L2YL 1EGFA 5CKQA 4X8VL 3N8WA 4RS0A 3TH3L 2RHPA 2RNLA 4D0FA 4E1GA 1WHEA 3HPTA 2W2ME 3N8XA 3QCWA 2AYLA 3KQCL 5JBAE 2FZZL 4JZEL 4BTUA 3POYA 1NFUB 1MOXC 3N8VA 4BDWA 1CVWL 1U8CB 4X8TL 3M36L 1IOXA 4XBMA 2VVUL 1W8BL 4RRZA 2EI7B 2XC0L 1L5GB 4BXWA 1NFYB 3LC5B 1PRHA 4ZXXL 1MQ5L 2VVVL 2VWLL 2W86A 4O02B 5JBBE 1ZAQA 3FCSB 4JZFL 1UZQA 2EI6B 2WG4B 3SOVA 1ATBA 2WPHE 1ATAA 4M10A 4CUDA 1M1XB 3P5BL 3SW2A 2WFTA 2J38B 1EZQB 5F1AA 4CSYA 3Q7DA 2BZ6L 1YUGA 4YZUB 2WG3C 5CKNA 1APOA 4NGAL 2VWNL 2BQ6A 1FSBA 1IQNL 2PR3B 1COUA 1TOZA 3KQDL 1IJQA 4MMYB 4ZH8B 3F1SB 1G1TA 1CCFA 2OYUP 2BOUA 5KN5C 1HRFA 3TGFA 4RRWA 1N1IA 1CEJA 2XBXL 2Y80B 1YO8A 3HS6A 4RUTA 5K0HB 3KRKA 2J4IB 2Y7ZB 2XC4L 1CVUA 1FAXL 5IKVA 2P28B 1F0SB 2FLBL 3U73A 3MDLA 1HT5A 1LMJA 2BMGA 2MGRA 5IKQA 2XC5L 3EGFA 1HAEA 1CQEA 1IGXA 5JVZA 1URKA 2B7DL 4NG9L 2Q1JB 2D1JB 4CUFA 4XLWA 1KLOA 1ATDA 1NT0A 1DVAL 4RRYA 1IQJL 1X7AL 3SOQA 5JBCE 1XDTR 1OB1C 3NJPC 4X8UL 2F9BL 3IITB 1IQHL 2WPJE 1IQIL 4OTJA 1KSNB 2VH0B 1EPGA 1FF7A 3HS7A 1F7EA 3H5CB 4A7IA 3FBYA 5CKMA 4BTTA 3CENL 2J94B 4CUEA 3KQBL 3SOBB 2WPKE 1EMOA 3ZYIB 1AUTL 1IQLL 1TPGA 2P94L 2H9EL 1BF9A 2P3FL 4BTIA 1PXXA 2PHBB 2W2QE 1LPZA 1PTHA 2DDUA 4JYUL 5FDQA 2TGFA 4ZXYL 1P0SL 4O1ZA 3F6UL 4ZAEB 2J34B 2VWOL 1I0UA 2Y38A 2Y82B 2UWLB 5JB9E 4TGFA 4Y76B 3KK6A 4M11A 3LIWB 2Y5HL 1NQLB 3BT1A 2JKHL 3KQEL 1APQA 2M74A 2MGPA 2WYJB 1UZPA 2OYEP 4XL1A 2I9BA 2YGPA 3GISX 3N8YB 1HX2A 1DDXA 4JYVL 1CX2A 1JL9A 2FD6A 6COXA 2BQWA 3ENSA 1CCVA 1O5DL 3ZYJB 4D90A 1YGCL 2KL7A 5F19A 1IQFL 4Z0KB 1G1QA 2UWPB 3HO5A 4FM5A 2G00L 1EPJA 2YGOA 1ATEA 4OTYA 3V65B 2W3KB 1G2MB 1DX5I 3QMOA 2VVCK 3Q3KB 4X8SL 1FFMA 2WYGB 1EMNA 1C5MF 2J95B 2J2UB 3ASIA 1NFXB 2P3UA 2XBVL 1EAIC 1IVOC 1G1RA 1WHFA 5JW1A 1IQEL 3LN0A 3U7UG 3FFGL 1EQGA 2KV4A 2P3FN 3N8WB 1U67A 1KIGL 1ADXA 1UZKA 1GK5A 1NZIA 1W7XL 4NA9L 4BDXA 2FLRL 1FAKL 1XKBA 3N8ZA 4RRXA 3CS7L 1IQML 2P95L 3HS5A 4MMZB 2K2TA 2W2PE 1TLEA 2P16L 3BPSE 1LPKA 1UZJA 2K2SB 3CFWA
chains in the Genus database with same CATH superfamily
3HO3A 2BT8A 2BQ7A 1FJSL 2Y7XB 1JV2B 1KLIL 2FLGA 1EQHA 1HCGB 2VWMK 1JBUL 3GCWE 1HJ7A 4MMXB 2RA0L 2W3IB 2P3TA 3ELAL 1PFXL 1MQ6L 1A3PA 2UWOB 1PGEA 2P93L 2Y81B 1IQGL 1N7DA 2W2OE 3NT1A 4Y79B 2WFXB 3KCGL 1K37A 1HREA 3V64C 3LC3B 4ISIL 1KLJL 2WPME 3C9AC 1G2LB 3RR3A 1F7MA 1F0RB 2BOXA 1WU1B 1LQDA 3S6XA 2BOHA 2GD4A 2VH6B 3BT2A 5CISA 3TK6B 1J9CL 3GCXE 1EBVA 2P26A 1SZBA 5E8DA 4JZDL 4COXA 2VJ3A 1EPIA 1LPGA 3R05A 1IQKL 5JVYA 5L30L 1IOEL 2BOKL 4YT7L 1XKAL 2W2NE 2CJIB 2HOXA 4Y7BB 2BO2A 2WPLE 2Y5FL 3LN1A 2MHPA 2WPIE 5I46L 1B9WA 5IKTA 5L2ZL 3KL6B 3TBDA 4AQTA 4LORA 4ZHAB 3QH0A 4Z0LA 5IKRA 3M37L 3IJEB 2XBYL 2W26B 3LAQA 1FE2A 3OLTA 4G1MB 4Z6AL 1NFWB 1Z6EL 3ZYGA 3OLUA 2ADXA 3N8YA 1RFNB 4LMFA 3TZIA 4YT6L 4ISHL 4Y7AB 1Q4GA 2BT7A 5EGMB 1DQBA 1Z6CA 1K36A 5COXA 3CA7A 1HAFA 2XBWL 2KB9A 3MQEA 3DEMA 1L3YA 1G1SA 1HT8A 3LTFB 1HZ8A 1XFEA 3NTGA 1YUFA 1IGZA 1QFKL 3TK5B 3PGHA 1NPEB 2EI8B 1EPHA 4D0EA 4Y6DB 1V1HA 4C16A 3K9XA 2PUQL 3HO4A 1IP0A 1DIYA 3LTGD 5JB8E 1P9JA 5KIRA 1YUKB 4Y71B 2I9AA 2NPRA 2Y5GL 1V3XB 3NTBA 4PH9A 4BXSA 5L2YL 1EGFA 5CKQA 4X8VL 4GU3A 3N8WA 4RS0A 3TH3L 2RHPA 2RNLA 4D0FA 4E1GA 1WHEA 3HPTA 2W2ME 3N8XA 3QCWA 2AYLA 3KQCL 5JBAE 2FZZL 4JZEL 4BTUA 3POYA 1NFUB 1MOXC 3N8VA 4BDWA 1CVWL 1U8CB 4X8TL 3M36L 1IOXA 4XBMA 2YGQA 2VVUL 1W8BL 4RRZA 2EI7B 2XC0L 1L5GB 4BXWA 1NFYB 3LC5B 1PRHA 4ZXXL 1MQ5L 2VVVL 2VWLL 2W86A 4O02B 5JBBE 1ZAQA 3FCSB 4JZFL 1UZQA 2EI6B 2WG4B 3SOVA 1ATBA 2WPHE 1ATAA 1QIUA 4M10A 4CUDA 1M1XB 3P5BL 3SW2A 2WFTA 2J38B 1EZQB 5F1AA 4CSYA 3Q7DA 2BZ6L 1YUGA 4YZUB 2WG3C 5CKNA 1APOA 4NGAL 2VWNL 2BQ6A 1FSBA 1IQNL 2PR3B 2WZPP 1COUA 1TOZA 3KQDL 1IJQA 4MMYB 4ZH8B 3F1SB 1G1TA 1CCFA 2OYUP 2BOUA 5KN5C 1HRFA 3TGFA 4RRWA 1N1IA 1CEJA 2XBXL 2HORA 2Y80B 1YO8A 3HS6A 4RUTA 5K0HB 3KRKA 2J4IB 2Y7ZB 2XC4L 1CVUA 1FAXL 5IKVA 2P28B 1F0SB 2FLBL 3U73A 3MDLA 1HT5A 1LMJA 2BMGA 2MGRA 5IKQA 2XC5L 3EGFA 1HAEA 1CQEA 1IGXA 5JVZA 1URKA 2B7DL 2H9EC 4NG9L 2Q1JB 2D1JB 4CUFA 4XLWA 1KLOA 1LK9A 1ATDA 1NT0A 1DVAL 4RRYA 1IQJL 1X7AL 3SOQA 5JBCE 1XDTR 1OB1C 3NJPC 4X8UL 2F9BL 3IITB 1KKEA 2BSFA 1IQHL 2WPJE 1IQIL 4OTJA 1KSNB 2VH0B 1EPGA 1FF7A 3HS7A 1F7EA 3H5CB 4A7IA 3FBYA 5CKMA 4BTTA 3CENL 2J94B 4GU4A 4CUEA 3KQBL 3SOBB 2WPKE 1EMOA 4A94C 3ZYIB 1AUTL 1IQLL 1TPGA 2P94L 2H9EL 1BF9A 2P3FL 4BTIA 1PXXA 2PHBB 2W2QE 1LPZA 1PTHA 2DDUA 4JYUL 5FDQA 2TGFA 4ZXYL 1P0SL 4O1ZA 3F6UL 4ZAEB 2J34B 2VWOL 1I0UA 2Y38A 2Y82B 2UWLB 5JB9E 4TGFA 4Y76B 2JJLA 3KK6A 4M11A 3LIWB 2Y5HL 1NQLB 3BT1A 2JKHL 3KQEL 1APQA 2M74A 2MGPA 2WYJB 1UZPA 1V1IA 2OYEP 4XL1A 2I9BA 2YGPA 3GISX 3N8YB 1HX2A 1DDXA 4JYVL 1CX2A 1JL9A 2FD6A 6COXA 2BQWA 3ENSA 1CCVA 1O5DL 3ZYJB 4D90A 1YGCL 2KL7A 5F19A 1IQFL 4Z0KB 1G1QA 2UWPB 3HO5A 4FM5A 2G00L 1EPJA 2YGOA 1ATEA 2VRSA 4OTYA 3V65B 2W3KB 1G2MB 1DX5I 3QMOA 2VVCK 3Q3KB 4X8SL 1FFMA 2WYGB 1EMNA 1C5MF 2J95B 2J2UB 3ASIA 1NFXB 2P3UA 2XBVL 1EAIC 1IVOC 1G1RA 1WHFA 5JW1A 1IQEL 3LN0A 3U7UG 3FFGL 1EQGA 2KV4A 2P3FN 3N8WB 1U67A 1KIGL 1ADXA 1UZKA 1GK5A 1NZIA 1W7XL 4NA9L 4BDXA 2FLRL 1FAKL 1XKBA 3N8ZA 4RRXA 3CS7L 1IQML 2P95L 3HS5A 4MMZB 2K2TA 2KNIA 2W2PE 1TLEA 2P16L 1LMMA 3BPSE 1LPKA 1UZJA 2K2SB 3CFWA
chains in the Genus database with same CATH topology
3HO3A 2BQ7A 1FJSL 2Y7XB 1JV2B 1KLIL 2FLGA 1EQHA 1HCGB 2VWMK 1JBUL 3GCWE 1HJ7A 4MMXB 2RA0L 2W3IB 2P3TA 3ELAL 1PFXL 1MQ6L 1A3PA 2UWOB 1PGEA 2P93L 2Y81B 1IQGL 1N7DA 2W2OE 3NT1A 4Y79B 2WFXB 3KCGL 1K37A 1HREA 3V64C 3LC3B 4ISIL 1KLJL 2WPME 3C9AC 1G2LB 3RR3A 1F7MA 1F0RB 2BOXA 1WU1B 1LQDA 3S6XA 2BOHA 2GD4A 2VH6B 3BT2A 5CISA 3TK6B 1J9CL 3GCXE 1EBVA 2P26A 1SZBA 5E8DA 4JZDL 4COXA 2VJ3A 1EPIA 1LPGA 3R05A 1IQKL 5JVYA 5L30L 1IOEL 2BOKL 4YT7L 1XKAL 2W2NE 2CJIB 4Y7BB 2BO2A 2WPLE 2Y5FL 3LN1A 2MHPA 2WPIE 5I46L 1B9WA 5IKTA 5L2ZL 3KL6B 3TBDA 4AQTA 4LORA 4ZHAB 3QH0A 4Z0LA 5IKRA 3M37L 3IJEB 2XBYL 2W26B 3LAQA 1FE2A 3OLTA 4G1MB 4Z6AL 1NFWB 1Z6EL 3ZYGA 3OLUA 2ADXA 3N8YA 1RFNB 4LMFA 3TZIA 4YT6L 4ISHL 4Y7AB 1Q4GA 5EGMB 1DQBA 1Z6CA 1K36A 5COXA 3CA7A 1HAFA 2XBWL 2KB9A 3MQEA 3DEMA 1L3YA 1G1SA 1HT8A 3LTFB 1HZ8A 1XFEA 3NTGA 1YUFA 1IGZA 1QFKL 3TK5B 3PGHA 1NPEB 2EI8B 1EPHA 4D0EA 4Y6DB 4C16A 3K9XA 2PUQL 3HO4A 1IP0A 1DIYA 3LTGD 5JB8E 1P9JA 5KIRA 1YUKB 4Y71B 2I9AA 2NPRA 2Y5GL 1V3XB 3NTBA 4PH9A 4BXSA 5L2YL 1EGFA 5CKQA 4X8VL 3N8WA 4RS0A 3TH3L 2RHPA 2RNLA 4D0FA 4E1GA 1WHEA 3HPTA 2W2ME 3N8XA 3QCWA 2AYLA 3KQCL 5JBAE 2FZZL 4JZEL 4BTUA 3POYA 1NFUB 1MOXC 3N8VA 4BDWA 1CVWL 1U8CB 4X8TL 3M36L 1IOXA 4XBMA 2YGQA 2VVUL 1W8BL 4RRZA 2EI7B 2XC0L 1L5GB 4BXWA 1NFYB 3LC5B 1PRHA 4ZXXL 1MQ5L 2VVVL 2VWLL 2W86A 4O02B 5JBBE 1ZAQA 3FCSB 4JZFL 1UZQA 2EI6B 2WG4B 3SOVA 1ATBA 2WPHE 1ATAA 4M10A 4CUDA 1M1XB 3P5BL 3SW2A 2WFTA 2J38B 1EZQB 5F1AA 4CSYA 3Q7DA 2BZ6L 1YUGA 4YZUB 2WG3C 5CKNA 1APOA 4NGAL 2VWNL 2BQ6A 1FSBA 1IQNL 2PR3B 2WZPP 1COUA 1TOZA 3KQDL 1IJQA 4MMYB 4ZH8B 3F1SB 1G1TA 1CCFA 2OYUP 2BOUA 5KN5C 1HRFA 3TGFA 4RRWA 1N1IA 1CEJA 2XBXL 2Y80B 1YO8A 3HS6A 4RUTA 5K0HB 3KRKA 2J4IB 2Y7ZB 2XC4L 1CVUA 1FAXL 5IKVA 2P28B 1F0SB 2FLBL 3U73A 3MDLA 1HT5A 1LMJA 2BMGA 2MGRA 5IKQA 2XC5L 3EGFA 1HAEA 1CQEA 1IGXA 5JVZA 1URKA 2B7DL 2H9EC 4NG9L 2Q1JB 2D1JB 4CUFA 4XLWA 1KLOA 1ATDA 1NT0A 1DVAL 4RRYA 1IQJL 1X7AL 3SOQA 5JBCE 1XDTR 1OB1C 3NJPC 4X8UL 2F9BL 3IITB 1IQHL 2WPJE 1IQIL 4OTJA 1KSNB 2VH0B 1EPGA 1FF7A 3HS7A 1F7EA 3H5CB 4A7IA 3FBYA 5CKMA 4BTTA 3CENL 2J94B 4CUEA 3KQBL 3SOBB 2WPKE 1EMOA 4A94C 3ZYIB 1AUTL 1IQLL 1TPGA 2P94L 2H9EL 1BF9A 2P3FL 4BTIA 1PXXA 2PHBB 2W2QE 1LPZA 1PTHA 2DDUA 4JYUL 5FDQA 2TGFA 4ZXYL 1P0SL 4O1ZA 3F6UL 4ZAEB 2J34B 2VWOL 1I0UA 2Y38A 2Y82B 2UWLB 5JB9E 4TGFA 4Y76B 3KK6A 4M11A 3LIWB 2Y5HL 1NQLB 3BT1A 2JKHL 3KQEL 1APQA 2M74A 2MGPA 2WYJB 1UZPA 2OYEP 4XL1A 2I9BA 2YGPA 3GISX 3N8YB 1HX2A 1DDXA 4JYVL 1CX2A 1JL9A 2FD6A 6COXA 2BQWA 3ENSA 1CCVA 1O5DL 3ZYJB 4D90A 1YGCL 2KL7A 5F19A 1IQFL 4Z0KB 1G1QA 2UWPB 3HO5A 4FM5A 2G00L 1EPJA 2YGOA 1ATEA 4OTYA 3V65B 2W3KB 1G2MB 1DX5I 3QMOA 2VVCK 3Q3KB 4X8SL 1FFMA 2WYGB 1EMNA 1C5MF 2J95B 2J2UB 3ASIA 1NFXB 2P3UA 2XBVL 1EAIC 1IVOC 1G1RA 1WHFA 5JW1A 1IQEL 3LN0A 3U7UG 3FFGL 1EQGA 2KV4A 2P3FN 3N8WB 1U67A 1KIGL 1ADXA 1UZKA 1GK5A 1NZIA 1W7XL 4NA9L 4BDXA 2FLRL 1FAKL 1XKBA 3N8ZA 4RRXA 3CS7L 1IQML 2P95L 3HS5A 4MMZB 2K2TA 2KNIA 2W2PE 1TLEA 2P16L 1LMMA 3BPSE 1LPKA 1UZJA 2K2SB 3CFWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HO3 A;  2BQ7 A;  1FJS L;  2Y7X B;  1JV2 B;  1KLI L;  2FLG A;  1EQH A;  1HCG B;  2VWM K;  1JBU L;  3GCW E;  1HJ7 A;  4MMX B;  2RA0 L;  2W3I B;  2P3T A;  3ELA L;  1PFX L;  1MQ6 L;  1A3P A;  2UWO B;  1PGE A;  2P93 L;  2Y81 B;  1IQG L;  1N7D A;  2W2O E;  3NT1 A;  4Y79 B;  2WFX B;  3KCG L;  1K37 A;  1HRE A;  3V64 C;  3LC3 B;  4ISI L;  1KLJ L;  2WPM E;  3C9A C;  1G2L B;  3RR3 A;  1F7M A;  1F0R B;  2BOX A;  1WU1 B;  1LQD A;  2BOH A;  2GD4 A;  2VH6 B;  3BT2 A;  5CIS A;  3TK6 B;  1J9C L;  3GCX E;  1EBV A;  2P26 A;  1SZB A;  5E8D A;  4JZD L;  4COX A;  2VJ3 A;  1EPI A;  1LPG A;  3R05 A;  1IQK L;  5JVY A;  5L30 L;  1IOE L;  2BOK L;  4YT7 L;  1XKA L;  2W2N E;  2CJI B;  4Y7B B;  2BO2 A;  2WPL E;  2Y5F L;  3LN1 A;  2MHP A;  2WPI E;  5I46 L;  1B9W A;  5IKT A;  5L2Z L;  3KL6 B;  3TBD A;  4AQT A;  4LOR A;  4ZHA B;  3QH0 A;  4Z0L A;  5IKR A;  3M37 L;  3IJE B;  2XBY L;  2W26 B;  3LAQ A;  1FE2 A;  3OLT A;  4G1M B;  4Z6A L;  1NFW B;  1Z6E L;  3ZYG A;  3OLU A;  2ADX A;  3N8Y A;  1RFN B;  4LMF A;  3TZI A;  4YT6 L;  4ISH L;  4Y7A B;  1Q4G A;  5EGM B;  1DQB A;  1Z6C A;  1K36 A;  5COX A;  3CA7 A;  1HAF A;  2XBW L;  2KB9 A;  3MQE A;  3DEM A;  1L3Y A;  1G1S A;  1HT8 A;  3LTF B;  1HZ8 A;  1XFE A;  3NTG A;  1YUF A;  1IGZ A;  1QFK L;  3TK5 B;  3PGH A;  1NPE B;  2EI8 B;  1EPH A;  4D0E A;  4Y6D B;  4C16 A;  3K9X A;  2PUQ L;  3HO4 A;  1IP0 A;  1DIY A;  3LTG D;  5JB8 E;  1P9J A;  5KIR A;  1YUK B;  4Y71 B;  2I9A A;  2NPR A;  2Y5G L;  1V3X B;  3NTB A;  4PH9 A;  4BXS A;  5L2Y L;  1EGF A;  5CKQ A;  4X8V L;  3N8W A;  4RS0 A;  3TH3 L;  2RHP A;  2RNL A;  4D0F A;  4E1G A;  1WHE A;  3HPT A;  2W2M E;  3N8X A;  3QCW A;  2AYL A;  3KQC L;  5JBA E;  2FZZ L;  4JZE L;  4BTU A;  3POY A;  1NFU B;  1MOX C;  3N8V A;  4BDW A;  1CVW L;  1U8C B;  4X8T L;  3M36 L;  1IOX A;  4XBM A;  2VVU L;  1W8B L;  4RRZ A;  2EI7 B;  2XC0 L;  1L5G B;  4BXW A;  1NFY B;  3LC5 B;  1PRH A;  4ZXX L;  1MQ5 L;  2VVV L;  2VWL L;  2W86 A;  4O02 B;  5JBB E;  1ZAQ A;  3FCS B;  4JZF L;  1UZQ A;  2EI6 B;  2WG4 B;  3SOV A;  1ATB A;  2WPH E;  1ATA A;  4M10 A;  4CUD A;  1M1X B;  3P5B L;  3SW2 A;  2WFT A;  2J38 B;  1EZQ B;  5F1A A;  4CSY A;  3Q7D A;  2BZ6 L;  1YUG A;  4YZU B;  2WG3 C;  5CKN A;  1APO A;  4NGA L;  2VWN L;  2BQ6 A;  1FSB A;  1IQN L;  2PR3 B;  1COU A;  1TOZ A;  3KQD L;  1IJQ A;  4MMY B;  4ZH8 B;  3F1S B;  1G1T A;  1CCF A;  2OYU P;  2BOU A;  5KN5 C;  1HRF A;  3TGF A;  4RRW A;  1N1I A;  1CEJ A;  2XBX L;  2Y80 B;  1YO8 A;  3HS6 A;  4RUT A;  5K0H B;  3KRK A;  2J4I B;  2Y7Z B;  2XC4 L;  1CVU A;  1FAX L;  5IKV A;  2P28 B;  1F0S B;  2FLB L;  3U73 A;  3MDL A;  1HT5 A;  1LMJ A;  2BMG A;  2MGR A;  5IKQ A;  2XC5 L;  3EGF A;  1HAE A;  1CQE A;  1IGX A;  5JVZ A;  1URK A;  2B7D L;  4NG9 L;  2Q1J B;  2D1J B;  4CUF A;  4XLW A;  1KLO A;  1ATD A;  1NT0 A;  1DVA L;  4RRY A;  1IQJ L;  1X7A L;  3SOQ A;  5JBC E;  1XDT R;  1OB1 C;  3NJP C;  4X8U L;  2F9B L;  3IIT B;  1IQH L;  2WPJ E;  1IQI L;  4OTJ A;  1KSN B;  2VH0 B;  1EPG A;  1FF7 A;  3HS7 A;  1F7E A;  3H5C B;  4A7I A;  3FBY A;  5CKM A;  4BTT A;  3CEN L;  2J94 B;  4CUE A;  3KQB L;  3SOB B;  2WPK E;  1EMO A;  3ZYI B;  1AUT L;  1IQL L;  1TPG A;  2P94 L;  2H9E L;  1BF9 A;  2P3F L;  4BTI A;  1PXX A;  2PHB B;  2W2Q E;  1LPZ A;  1PTH A;  2DDU A;  4JYU L;  5FDQ A;  2TGF A;  4ZXY L;  1P0S L;  4O1Z A;  3F6U L;  4ZAE B;  2J34 B;  2VWO L;  1I0U A;  2Y38 A;  2Y82 B;  2UWL B;  5JB9 E;  4TGF A;  4Y76 B;  3KK6 A;  4M11 A;  3LIW B;  2Y5H L;  1NQL B;  3BT1 A;  2JKH L;  3KQE L;  1APQ A;  2M74 A;  2MGP A;  2WYJ B;  1UZP A;  2OYE P;  4XL1 A;  2I9B A;  2YGP A;  3GIS X;  3N8Y B;  1HX2 A;  1DDX A;  4JYV L;  1CX2 A;  1JL9 A;  2FD6 A;  6COX A;  2BQW A;  3ENS A;  1CCV A;  1O5D L;  3ZYJ B;  4D90 A;  1YGC L;  2KL7 A;  5F19 A;  1IQF L;  4Z0K B;  1G1Q A;  2UWP B;  3HO5 A;  4FM5 A;  2G00 L;  1EPJ A;  2YGO A;  1ATE A;  4OTY A;  3V65 B;  2W3K B;  1G2M B;  1DX5 I;  3QMO A;  2VVC K;  3Q3K B;  4X8S L;  1FFM A;  2WYG B;  1EMN A;  1C5M F;  2J95 B;  2J2U B;  3ASI A;  1NFX B;  2P3U A;  2XBV L;  1EAI C;  1IVO C;  1G1R A;  1WHF A;  5JW1 A;  1IQE L;  3LN0 A;  3U7U G;  3FFG L;  1EQG A;  2KV4 A;  2P3F N;  3N8W B;  1U67 A;  1KIG L;  1ADX A;  1UZK A;  1GK5 A;  1NZI A;  1W7X L;  4NA9 L;  4BDX A;  2FLR L;  1FAK L;  1XKB A;  3N8Z A;  4RRX A;  3CS7 L;  1IQM L;  2P95 L;  3HS5 A;  4MMZ B;  2K2T A;  2W2P E;  1TLE A;  2P16 L;  3BPS E;  1LPK A;  1UZJ A;  2K2S B;  3CFW A; 
#chains in the Genus database with same CATH topology
 3HO3 A;  2BT8 A;  2BQ7 A;  1FJS L;  2Y7X B;  1JV2 B;  1KLI L;  2FLG A;  1EQH A;  1HCG B;  2VWM K;  1JBU L;  3GCW E;  1HJ7 A;  4MMX B;  2RA0 L;  2W3I B;  2P3T A;  3ELA L;  1PFX L;  1MQ6 L;  1A3P A;  2UWO B;  1PGE A;  2P93 L;  2Y81 B;  1IQG L;  1N7D A;  2W2O E;  3NT1 A;  4Y79 B;  2WFX B;  3KCG L;  1K37 A;  1HRE A;  3V64 C;  3LC3 B;  4ISI L;  1KLJ L;  2WPM E;  3C9A C;  1G2L B;  3RR3 A;  1F7M A;  1F0R B;  2BOX A;  1WU1 B;  1LQD A;  3S6X A;  2BOH A;  2GD4 A;  2VH6 B;  3BT2 A;  5CIS A;  3TK6 B;  1J9C L;  3GCX E;  1EBV A;  2P26 A;  1SZB A;  5E8D A;  4JZD L;  4COX A;  2VJ3 A;  1EPI A;  1LPG A;  3R05 A;  1IQK L;  5JVY A;  5L30 L;  1IOE L;  2BOK L;  4YT7 L;  1XKA L;  2W2N E;  2CJI B;  2HOX A;  4Y7B B;  2BO2 A;  2WPL E;  2Y5F L;  3LN1 A;  2MHP A;  2WPI E;  5I46 L;  1B9W A;  5IKT A;  5L2Z L;  3KL6 B;  3TBD A;  4AQT A;  4LOR A;  4ZHA B;  3QH0 A;  4Z0L A;  5IKR A;  3M37 L;  3IJE B;  2XBY L;  2W26 B;  3LAQ A;  1FE2 A;  3OLT A;  4G1M B;  4Z6A L;  1NFW B;  1Z6E L;  3ZYG A;  3OLU A;  2ADX A;  3N8Y A;  1RFN B;  4LMF A;  3TZI A;  4YT6 L;  4ISH L;  4Y7A B;  1Q4G A;  2BT7 A;  5EGM B;  1DQB A;  1Z6C A;  1K36 A;  5COX A;  3CA7 A;  1HAF A;  2XBW L;  2KB9 A;  3MQE A;  3DEM A;  1L3Y A;  1G1S A;  1HT8 A;  3LTF B;  1HZ8 A;  1XFE A;  3NTG A;  1YUF A;  1IGZ A;  1QFK L;  3TK5 B;  3PGH A;  1NPE B;  2EI8 B;  1EPH A;  4D0E A;  4Y6D B;  1V1H A;  4C16 A;  3K9X A;  2PUQ L;  3HO4 A;  1IP0 A;  1DIY A;  3LTG D;  5JB8 E;  1P9J A;  5KIR A;  1YUK B;  4Y71 B;  2I9A A;  2NPR A;  2Y5G L;  1V3X B;  3NTB A;  4PH9 A;  4BXS A;  5L2Y L;  1EGF A;  5CKQ A;  4X8V L;  4GU3 A;  3N8W A;  4RS0 A;  3TH3 L;  2RHP A;  2RNL A;  4D0F A;  4E1G A;  1WHE A;  3HPT A;  2W2M E;  3N8X A;  3QCW A;  2AYL A;  3KQC L;  5JBA E;  2FZZ L;  4JZE L;  4BTU A;  3POY A;  1NFU B;  1MOX C;  3N8V A;  4BDW A;  1CVW L;  1U8C B;  4X8T L;  3M36 L;  1IOX A;  4XBM A;  2YGQ A;  2VVU L;  1W8B L;  4RRZ A;  2EI7 B;  2XC0 L;  1L5G B;  4BXW A;  1NFY B;  3LC5 B;  1PRH A;  4ZXX L;  1MQ5 L;  2VVV L;  2VWL L;  2W86 A;  4O02 B;  5JBB E;  1ZAQ A;  3FCS B;  4JZF L;  1UZQ A;  2EI6 B;  2WG4 B;  3SOV A;  1ATB A;  2WPH E;  1ATA A;  1QIU A;  4M10 A;  4CUD A;  1M1X B;  3P5B L;  3SW2 A;  2WFT A;  2J38 B;  1EZQ B;  5F1A A;  4CSY A;  3Q7D A;  2BZ6 L;  1YUG A;  4YZU B;  2WG3 C;  5CKN A;  1APO A;  4NGA L;  2VWN L;  2BQ6 A;  1FSB A;  1IQN L;  2PR3 B;  2WZP P;  1COU A;  1TOZ A;  3KQD L;  1IJQ A;  4MMY B;  4ZH8 B;  3F1S B;  1G1T A;  1CCF A;  2OYU P;  2BOU A;  5KN5 C;  1HRF A;  3TGF A;  4RRW A;  1N1I A;  1CEJ A;  2XBX L;  2HOR A;  2Y80 B;  1YO8 A;  3HS6 A;  4RUT A;  5K0H B;  3KRK A;  2J4I B;  2Y7Z B;  2XC4 L;  1CVU A;  1FAX L;  5IKV A;  2P28 B;  1F0S B;  2FLB L;  3U73 A;  3MDL A;  1HT5 A;  1LMJ A;  2BMG A;  2MGR A;  5IKQ A;  2XC5 L;  3EGF A;  1HAE A;  1CQE A;  1IGX A;  5JVZ A;  1URK A;  2B7D L;  2H9E C;  4NG9 L;  2Q1J B;  2D1J B;  4CUF A;  4XLW A;  1KLO A;  1LK9 A;  1ATD A;  1NT0 A;  1DVA L;  4RRY A;  1IQJ L;  1X7A L;  3SOQ A;  5JBC E;  1XDT R;  1OB1 C;  3NJP C;  4X8U L;  2F9B L;  3IIT B;  1KKE A;  2BSF A;  1IQH L;  2WPJ E;  1IQI L;  4OTJ A;  1KSN B;  2VH0 B;  1EPG A;  1FF7 A;  3HS7 A;  1F7E A;  3H5C B;  4A7I A;  3FBY A;  5CKM A;  4BTT A;  3CEN L;  2J94 B;  4GU4 A;  4CUE A;  3KQB L;  3SOB B;  2WPK E;  1EMO A;  4A94 C;  3ZYI B;  1AUT L;  1IQL L;  1TPG A;  2P94 L;  2H9E L;  1BF9 A;  2P3F L;  4BTI A;  1PXX A;  2PHB B;  2W2Q E;  1LPZ A;  1PTH A;  2DDU A;  4JYU L;  5FDQ A;  2TGF A;  4ZXY L;  1P0S L;  4O1Z A;  3F6U L;  4ZAE B;  2J34 B;  2VWO L;  1I0U A;  2Y38 A;  2Y82 B;  2UWL B;  5JB9 E;  4TGF A;  4Y76 B;  2JJL A;  3KK6 A;  4M11 A;  3LIW B;  2Y5H L;  1NQL B;  3BT1 A;  2JKH L;  3KQE L;  1APQ A;  2M74 A;  2MGP A;  2WYJ B;  1UZP A;  1V1I A;  2OYE P;  4XL1 A;  2I9B A;  2YGP A;  3GIS X;  3N8Y B;  1HX2 A;  1DDX A;  4JYV L;  1CX2 A;  1JL9 A;  2FD6 A;  6COX A;  2BQW A;  3ENS A;  1CCV A;  1O5D L;  3ZYJ B;  4D90 A;  1YGC L;  2KL7 A;  5F19 A;  1IQF L;  4Z0K B;  1G1Q A;  2UWP B;  3HO5 A;  4FM5 A;  2G00 L;  1EPJ A;  2YGO A;  1ATE A;  2VRS A;  4OTY A;  3V65 B;  2W3K B;  1G2M B;  1DX5 I;  3QMO A;  2VVC K;  3Q3K B;  4X8S L;  1FFM A;  2WYG B;  1EMN A;  1C5M F;  2J95 B;  2J2U B;  3ASI A;  1NFX B;  2P3U A;  2XBV L;  1EAI C;  1IVO C;  1G1R A;  1WHF A;  5JW1 A;  1IQE L;  3LN0 A;  3U7U G;  3FFG L;  1EQG A;  2KV4 A;  2P3F N;  3N8W B;  1U67 A;  1KIG L;  1ADX A;  1UZK A;  1GK5 A;  1NZI A;  1W7X L;  4NA9 L;  4BDX A;  2FLR L;  1FAK L;  1XKB A;  3N8Z A;  4RRX A;  3CS7 L;  1IQM L;  2P95 L;  3HS5 A;  4MMZ B;  2K2T A;  2KNI A;  2W2P E;  1TLE A;  2P16 L;  1LMM A;  3BPS E;  1LPK A;  1UZJ A;  2K2S B;  3CFW A; 
#chains in the Genus database with same CATH homology
 3HO3 A;  2BQ7 A;  1FJS L;  2Y7X B;  1JV2 B;  1KLI L;  2FLG A;  1EQH A;  1HCG B;  2VWM K;  1JBU L;  3GCW E;  1HJ7 A;  4MMX B;  2RA0 L;  2W3I B;  2P3T A;  3ELA L;  1PFX L;  1MQ6 L;  1A3P A;  2UWO B;  1PGE A;  2P93 L;  2Y81 B;  1IQG L;  1N7D A;  2W2O E;  3NT1 A;  4Y79 B;  2WFX B;  3KCG L;  1K37 A;  1HRE A;  3V64 C;  3LC3 B;  4ISI L;  1KLJ L;  2WPM E;  3C9A C;  1G2L B;  3RR3 A;  1F7M A;  1F0R B;  2BOX A;  1WU1 B;  1LQD A;  3S6X A;  2BOH A;  2GD4 A;  2VH6 B;  3BT2 A;  5CIS A;  3TK6 B;  1J9C L;  3GCX E;  1EBV A;  2P26 A;  1SZB A;  5E8D A;  4JZD L;  4COX A;  2VJ3 A;  1EPI A;  1LPG A;  3R05 A;  1IQK L;  5JVY A;  5L30 L;  1IOE L;  2BOK L;  4YT7 L;  1XKA L;  2W2N E;  2CJI B;  4Y7B B;  2BO2 A;  2WPL E;  2Y5F L;  3LN1 A;  2MHP A;  2WPI E;  5I46 L;  1B9W A;  5IKT A;  5L2Z L;  3KL6 B;  3TBD A;  4AQT A;  4LOR A;  4ZHA B;  3QH0 A;  4Z0L A;  5IKR A;  3M37 L;  3IJE B;  2XBY L;  2W26 B;  3LAQ A;  1FE2 A;  3OLT A;  4G1M B;  4Z6A L;  1NFW B;  1Z6E L;  3ZYG A;  3OLU A;  2ADX A;  3N8Y A;  1RFN B;  4LMF A;  3TZI A;  4YT6 L;  4ISH L;  4Y7A B;  1Q4G A;  5EGM B;  1DQB A;  1Z6C A;  1K36 A;  5COX A;  3CA7 A;  1HAF A;  2XBW L;  2KB9 A;  3MQE A;  3DEM A;  1L3Y A;  1G1S A;  1HT8 A;  3LTF B;  1HZ8 A;  1XFE A;  3NTG A;  1YUF A;  1IGZ A;  1QFK L;  3TK5 B;  3PGH A;  1NPE B;  2EI8 B;  1EPH A;  4D0E A;  4Y6D B;  4C16 A;  3K9X A;  2PUQ L;  3HO4 A;  1IP0 A;  1DIY A;  3LTG D;  5JB8 E;  1P9J A;  5KIR A;  1YUK B;  4Y71 B;  2I9A A;  2NPR A;  2Y5G L;  1V3X B;  3NTB A;  4PH9 A;  4BXS A;  5L2Y L;  1EGF A;  5CKQ A;  4X8V L;  3N8W A;  4RS0 A;  3TH3 L;  2RHP A;  2RNL A;  4D0F A;  4E1G A;  1WHE A;  3HPT A;  2W2M E;  3N8X A;  3QCW A;  2AYL A;  3KQC L;  5JBA E;  2FZZ L;  4JZE L;  4BTU A;  3POY A;  1NFU B;  1MOX C;  3N8V A;  4BDW A;  1CVW L;  1U8C B;  4X8T L;  3M36 L;  1IOX A;  4XBM A;  2YGQ A;  2VVU L;  1W8B L;  4RRZ A;  2EI7 B;  2XC0 L;  1L5G B;  4BXW A;  1NFY B;  3LC5 B;  1PRH A;  4ZXX L;  1MQ5 L;  2VVV L;  2VWL L;  2W86 A;  4O02 B;  5JBB E;  1ZAQ A;  3FCS B;  4JZF L;  1UZQ A;  2EI6 B;  2WG4 B;  3SOV A;  1ATB A;  2WPH E;  1ATA A;  4M10 A;  4CUD A;  1M1X B;  3P5B L;  3SW2 A;  2WFT A;  2J38 B;  1EZQ B;  5F1A A;  4CSY A;  3Q7D A;  2BZ6 L;  1YUG A;  4YZU B;  2WG3 C;  5CKN A;  1APO A;  4NGA L;  2VWN L;  2BQ6 A;  1FSB A;  1IQN L;  2PR3 B;  2WZP P;  1COU A;  1TOZ A;  3KQD L;  1IJQ A;  4MMY B;  4ZH8 B;  3F1S B;  1G1T A;  1CCF A;  2OYU P;  2BOU A;  5KN5 C;  1HRF A;  3TGF A;  4RRW A;  1N1I A;  1CEJ A;  2XBX L;  2Y80 B;  1YO8 A;  3HS6 A;  4RUT A;  5K0H B;  3KRK A;  2J4I B;  2Y7Z B;  2XC4 L;  1CVU A;  1FAX L;  5IKV A;  2P28 B;  1F0S B;  2FLB L;  3U73 A;  3MDL A;  1HT5 A;  1LMJ A;  2BMG A;  2MGR A;  5IKQ A;  2XC5 L;  3EGF A;  1HAE A;  1CQE A;  1IGX A;  5JVZ A;  1URK A;  2B7D L;  2H9E C;  4NG9 L;  2Q1J B;  2D1J B;  4CUF A;  4XLW A;  1KLO A;  1ATD A;  1NT0 A;  1DVA L;  4RRY A;  1IQJ L;  1X7A L;  3SOQ A;  5JBC E;  1XDT R;  1OB1 C;  3NJP C;  4X8U L;  2F9B L;  3IIT B;  1IQH L;  2WPJ E;  1IQI L;  4OTJ A;  1KSN B;  2VH0 B;  1EPG A;  1FF7 A;  3HS7 A;  1F7E A;  3H5C B;  4A7I A;  3FBY A;  5CKM A;  4BTT A;  3CEN L;  2J94 B;  4CUE A;  3KQB L;  3SOB B;  2WPK E;  1EMO A;  4A94 C;  3ZYI B;  1AUT L;  1IQL L;  1TPG A;  2P94 L;  2H9E L;  1BF9 A;  2P3F L;  4BTI A;  1PXX A;  2PHB B;  2W2Q E;  1LPZ A;  1PTH A;  2DDU A;  4JYU L;  5FDQ A;  2TGF A;  4ZXY L;  1P0S L;  4O1Z A;  3F6U L;  4ZAE B;  2J34 B;  2VWO L;  1I0U A;  2Y38 A;  2Y82 B;  2UWL B;  5JB9 E;  4TGF A;  4Y76 B;  3KK6 A;  4M11 A;  3LIW B;  2Y5H L;  1NQL B;  3BT1 A;  2JKH L;  3KQE L;  1APQ A;  2M74 A;  2MGP A;  2WYJ B;  1UZP A;  2OYE P;  4XL1 A;  2I9B A;  2YGP A;  3GIS X;  3N8Y B;  1HX2 A;  1DDX A;  4JYV L;  1CX2 A;  1JL9 A;  2FD6 A;  6COX A;  2BQW A;  3ENS A;  1CCV A;  1O5D L;  3ZYJ B;  4D90 A;  1YGC L;  2KL7 A;  5F19 A;  1IQF L;  4Z0K B;  1G1Q A;  2UWP B;  3HO5 A;  4FM5 A;  2G00 L;  1EPJ A;  2YGO A;  1ATE A;  4OTY A;  3V65 B;  2W3K B;  1G2M B;  1DX5 I;  3QMO A;  2VVC K;  3Q3K B;  4X8S L;  1FFM A;  2WYG B;  1EMN A;  1C5M F;  2J95 B;  2J2U B;  3ASI A;  1NFX B;  2P3U A;  2XBV L;  1EAI C;  1IVO C;  1G1R A;  1WHF A;  5JW1 A;  1IQE L;  3LN0 A;  3U7U G;  3FFG L;  1EQG A;  2KV4 A;  2P3F N;  3N8W B;  1U67 A;  1KIG L;  1ADX A;  1UZK A;  1GK5 A;  1NZI A;  1W7X L;  4NA9 L;  4BDX A;  2FLR L;  1FAK L;  1XKB A;  3N8Z A;  4RRX A;  3CS7 L;  1IQM L;  2P95 L;  3HS5 A;  4MMZ B;  2K2T A;  2KNI A;  2W2P E;  1TLE A;  2P16 L;  1LMM A;  3BPS E;  1LPK A;  1UZJ A;  2K2S B;  3CFW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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