3NJPC

The extracellular and transmembrane domain interfaces in epidermal growth factor receptor signaling
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
47
structure length
47
Chain Sequence
ECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWWE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural evidence for loose linkage between ligand binding and kinase activation in the epidermal growth factor receptor.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Epidermal growth factor receptor
total genus 7
structure length 47
sequence length 47
chains with identical sequence D
ec nomenclature
pdb deposition date 2010-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00008 EGF EGF-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3njpC00
2BOHA 3CFWA 1NFXB 2VVUL 3SOQA 2BMGA 3FCSB 1GK5A 3HPTA 2VWNL 5COXA 2FLBL 1V3XB 3N8VA 2ADXA 3HS6A 1HT8A 3TZIA 4D0EA 3LN0A 3C9AC 4CUFA 1DVAL 1HAEA 1F0SB 2YGPA 2VVVL 2VH6B 4Y6DB 3BPSE 5IKVA 1NFYB 1IQLL 4NGAL 1CVUA 1C5MF 1SZBA 1EBVA 1FSBA 1WHFA 5JB9E 2FLRL 2RA0L 3PGHA 3CS7L 5L2YL 2P95L 3M37L 2W2ME 2BOUA 3LN1A 2MHPA 4ISHL 1Z6EL 2KV4A 4JZFL 2WPKE 3GCXE 5JBAE 1F0RB 2J38B 1IOXA 2WPLE 2P3FL 3U73A 3MQEA 1PTHA 1ATEA 3V65B 3ELAL 3FBYA 1FF7A 4NG9L 3TH3L 3NTGA 2B7DL 3QCWA 5F19A 2XC0L 1IQKL 4ZXYL 2M74A 3POYA 1B9WA 2WPHE 1IQJL 2GD4A 5FDQA 3IITB 4X8VL 4OTYA 2I9BA 1TLEA 1IGZA 4JZDL 1UZJA 3M36L 4O02B 3BT2A 1MQ6L 1P0SL 1ZAQA 1APQA 1URKA 2P93L 2VWOL 4FM5A 1X7AL 5I46L 4RRZA 1G2MB 3LC5B 1J9CL 4JYVL 4Y71B 3RR3A 2P3UA 4MMYB 4ZH8B 5IKRA 2DDUA 1EPIA 4PH9A 4Y7BB 1K37A 2P16L 3F1SB 2W2PE 4D0FA 1YO8A 1FAXL 2W3IB 1O5DL 1WU1B 2NPRA 1JL9A 4Z0KB 2VH0B 2Y38A 1HREA 3DEMA 3KQDL 1OB1C 3TK6B 2WFXB 1IQHL 4X8UL 4BXSA 1HRFA 1UZPA 2WPIE 5CISA 1MQ5L 2XBXL 5L30L 1N7DA 1JV2B 3EGFA 1LPGA 4AQTA 2Q1JB 1IQEL 1G1SA 1KLJL 3FFGL 1QFKL 3SOVA 2KB9A 1PRHA 3HS5A 3KQBL 2VWLL 2P94L 3V64C 1COUA 1NQLB 1MOXC 4M10A 3ASIA 1XDTR 3ZYJB 1IP0A 2P28B 1A3PA 1UZQA 1I0UA 2F9BL 1NFWB 2WG4B 1APOA 2BQ6A 4D90A 2BOXA 1HT5A 1K36A 1CCVA 1YUKB 1IVOC 3QMOA 2WG3C 1PGEA 3OLTA 1IQIL 1EQHA 6COXA 1EMNA 1LPZA 3H5CB 1XKBA 2KL7A 4Z0LA 1EGFA 5KIRA 1RFNB 2Y5FL 2VWMK 2P3FN 2PUQL 2J2UB 2TGFA 2WFTA 5JW1A 3KQCL 1KIGL 4LORA 3R05A 1IJQA 1HX2A 1AUTL 4BTUA 3HS7A 3CENL 1HAFA 4NA9L 4BXWA 1JBUL 4RRXA 4MMXB 1F7MA 1LQDA 1NT0A 4TGFA 1CVWL 2Y7ZB 4BDXA 2OYEP 1TPGA 1PFXL 3Q3KB 4ZHAB 4RS0A 1IQFL 1W8BL 2J95B 1ATBA 1U67A 2FZZL 1WHEA 2H9EL 5E8DA 2K2TA 1EAIC 4Y79B 4CUDA 3LIWB 3TGFA 3N8WB 3HO5A 4M11A 1IGXA 3U7UG 2J34B 1TOZA 5CKMA 5JBBE 4G1MB 1FAKL 3NJPC 1DX5I 1DQBA 2Y7XB 2CJIB 2MGPA 5K0HB 1PXXA 2Y80B 2W86A 4Z6AL 3KL6B 2XC5L 4C16A 1UZKA 2W26B 2AYLA 2UWPB 3LAQA 1NFUB 4JYUL 1XKAL 3P5BL 5JVYA 1IOEL 1LMJA 1EPGA 1LPKA 1FFMA 1CCFA 1CEJA 3N8YB 2YGOA 5JVZA 1N1IA 3TBDA 5EGMB 2RNLA 4ZXXL 4COXA 2BOKL 3LTGD 3OLUA 1DIYA 1KLIL 3LTFB 1IQNL 4A7IA 1G1RA 2RHPA 2WYJB 3SW2A 5CKNA 2W3KB 2I9AA 2FLGA 1EPJA 1DDXA 3NTBA 1CX2A 2JKHL 4CSYA 3ZYIB 1YGCL 3N8YA 1U8CB 3SOBB 1Z6CA 3CA7A 4XLWA 2XC4L 1M1XB 2WPME 2OYUP 5IKQA 3ZYGA 4E1GA 1KSNB 1YUFA 1BF9A 1HJ7A 2EI7B 2XBWL 1NZIA 4RUTA 3KK6A 2XBVL 4YZUB 4BTTA 5KN5C 1L3YA 1F7EA 2PHBB 2WPJE 4XL1A 1Q4GA 2Y82B 1ATDA 2Y5HL 4ISIL 3HO3A 4Y76B 1CQEA 4BTIA 2BZ6L 3QH0A 4XBMA 2P26A 3HO4A 2EI8B 1P9JA 3KCGL 1G2LB 1G1TA 4RRWA 3F6UL 3IJEB 4JZEL 3ENSA 4YT7L 2P3TA 1ATAA 1G1QA 4O1ZA 5JBCE 2K2SB 1FJSL 2J4IB 1EMOA 3MDLA 4X8SL 1NPEB 2BQWA 2Y5GL 1KLOA 1YUGA 4X8TL 2XBYL 1IQML 2VJ3A 4YT6L 2FD6A 4MMZB 2MGRA 4ZAEB 2PR3B 1XFEA 1IQGL 1EQGA 1ADXA 2W2OE 3N8ZA 2EI6B 3GCWE 3TK5B 3K9XA 5F1AA 4BDWA 3KQEL 2WYGB 1EPHA 3Q7DA 1W7XL 2G00L 3N8WA 2W2QE 1L5GB 2UWLB 1EZQB 1HZ8A 4Y7AB 2BQ7A 2BO2A 2D1JB 2W2NE 4OTJA 5IKTA 5JB8E 2J94B 3NT1A 5CKQA 1HCGB 4CUEA 3LC3B 4RRYA 3GISX 3KRKA 4LMFA 2UWOB 3BT1A 3N8XA 5L2ZL 2VVCK 1FE2A 2Y81B
chains in the Genus database with same CATH superfamily
2BOHA 3CFWA 1NFXB 2VVUL 3SOQA 2BMGA 3FCSB 1GK5A 3HPTA 2VWNL 5COXA 2FLBL 1V3XB 3N8VA 2ADXA 3HS6A 1HT8A 3TZIA 4D0EA 3LN0A 3C9AC 4CUFA 1DVAL 1HAEA 1F0SB 2YGPA 2VVVL 2VH6B 4Y6DB 3BPSE 5IKVA 1NFYB 1IQLL 4A94C 4NGAL 1CVUA 1C5MF 1SZBA 1EBVA 1FSBA 1WHFA 5JB9E 2FLRL 2RA0L 3PGHA 3CS7L 5L2YL 2P95L 3M37L 2W2ME 2BOUA 3LN1A 2MHPA 4ISHL 1Z6EL 2KV4A 4JZFL 2WPKE 3GCXE 5JBAE 1F0RB 2J38B 1IOXA 2WPLE 2P3FL 3U73A 3MQEA 1PTHA 1ATEA 3V65B 3ELAL 3FBYA 1FF7A 4NG9L 3TH3L 3NTGA 2B7DL 3QCWA 2BSFA 5F19A 2XC0L 1IQKL 4ZXYL 2M74A 3POYA 1B9WA 2WPHE 1IQJL 2GD4A 5FDQA 3IITB 4X8VL 4OTYA 2I9BA 1TLEA 1IGZA 4JZDL 1UZJA 3M36L 4O02B 3BT2A 1MQ6L 1P0SL 1ZAQA 1APQA 1URKA 2P93L 2VWOL 4FM5A 1X7AL 5I46L 4RRZA 1G2MB 3LC5B 1J9CL 4JYVL 4Y71B 3RR3A 2P3UA 4MMYB 4ZH8B 5IKRA 2YGQA 2DDUA 1EPIA 4PH9A 4Y7BB 1K37A 2P16L 3F1SB 2W2PE 4D0FA 1YO8A 1FAXL 2W3IB 1O5DL 1WU1B 2NPRA 1JL9A 4Z0KB 2VH0B 2Y38A 1HREA 3DEMA 3KQDL 2H9EC 1OB1C 1QIUA 3TK6B 2WFXB 1IQHL 4X8UL 4BXSA 1HRFA 1UZPA 2VRSA 2WPIE 5CISA 1MQ5L 2XBXL 5L30L 1N7DA 1JV2B 3EGFA 1LPGA 4AQTA 2Q1JB 1IQEL 1G1SA 1KLJL 3FFGL 1QFKL 3SOVA 2KB9A 1PRHA 3HS5A 3KQBL 2VWLL 2P94L 3V64C 1COUA 1NQLB 1MOXC 4M10A 3ASIA 1XDTR 3ZYJB 1IP0A 2P28B 1A3PA 1UZQA 1I0UA 2F9BL 1NFWB 2WG4B 1APOA 2BQ6A 4D90A 2BOXA 1HT5A 1K36A 1CCVA 1YUKB 1IVOC 3QMOA 2WG3C 1PGEA 3OLTA 1IQIL 1EQHA 6COXA 1EMNA 1LPZA 3H5CB 1XKBA 2KL7A 4Z0LA 1EGFA 5KIRA 1RFNB 2Y5FL 2VWMK 2P3FN 2PUQL 2J2UB 2TGFA 2WFTA 5JW1A 3KQCL 1KIGL 4LORA 3R05A 1IJQA 1HX2A 1AUTL 4BTUA 3HS7A 3CENL 1HAFA 4NA9L 4BXWA 1JBUL 2WZPP 2HOXA 4RRXA 4MMXB 1F7MA 1LQDA 1NT0A 4TGFA 1CVWL 2Y7ZB 4BDXA 2OYEP 2JJLA 1TPGA 1PFXL 3Q3KB 4ZHAB 4RS0A 1IQFL 1W8BL 2J95B 1ATBA 1U67A 2FZZL 1WHEA 2H9EL 5E8DA 2K2TA 1EAIC 4Y79B 4CUDA 3LIWB 3TGFA 3N8WB 3HO5A 4M11A 1IGXA 3U7UG 2J34B 1TOZA 5CKMA 2KNIA 5JBBE 4G1MB 1FAKL 3NJPC 1DX5I 1DQBA 2Y7XB 2CJIB 2MGPA 5K0HB 1PXXA 2Y80B 2W86A 4Z6AL 3KL6B 2XC5L 4C16A 1UZKA 2W26B 2AYLA 2UWPB 3LAQA 1NFUB 4JYUL 1XKAL 3P5BL 5JVYA 1IOEL 1LMJA 1EPGA 1LPKA 1FFMA 1CCFA 1CEJA 3N8YB 2YGOA 5JVZA 1N1IA 3TBDA 5EGMB 2RNLA 4ZXXL 4COXA 2BOKL 3LTGD 3OLUA 1DIYA 1KLIL 3LTFB 1IQNL 4A7IA 1G1RA 2RHPA 2WYJB 3SW2A 5CKNA 2W3KB 2I9AA 2FLGA 1EPJA 1DDXA 3NTBA 1CX2A 2JKHL 4CSYA 3ZYIB 1YGCL 3N8YA 1U8CB 3SOBB 1Z6CA 3CA7A 4XLWA 2XC4L 1M1XB 2WPME 2OYUP 5IKQA 3ZYGA 4E1GA 1KSNB 1YUFA 1BF9A 1HJ7A 2EI7B 2XBWL 1NZIA 4RUTA 3KK6A 2XBVL 4YZUB 4BTTA 5KN5C 1L3YA 1F7EA 2PHBB 2WPJE 4XL1A 1Q4GA 2Y82B 1ATDA 2Y5HL 4ISIL 3HO3A 4Y76B 1CQEA 4BTIA 2BZ6L 3QH0A 4XBMA 2P26A 3HO4A 2EI8B 1P9JA 3KCGL 1G2LB 1G1TA 4RRWA 3S6XA 2BT7A 3F6UL 3IJEB 4JZEL 3ENSA 4YT7L 2P3TA 1ATAA 1G1QA 1LMMA 4O1ZA 5JBCE 2K2SB 1FJSL 2J4IB 1EMOA 3MDLA 4X8SL 1NPEB 2BQWA 2Y5GL 1KLOA 1YUGA 4X8TL 2XBYL 1IQML 2VJ3A 4YT6L 2FD6A 4MMZB 2MGRA 4ZAEB 1V1IA 2PR3B 1XFEA 1IQGL 1KKEA 1EQGA 1ADXA 2W2OE 3N8ZA 2EI6B 3GCWE 2HORA 3TK5B 3K9XA 5F1AA 4BDWA 1LK9A 3KQEL 4GU3A 2WYGB 4GU4A 1EPHA 2BT8A 3Q7DA 1W7XL 2G00L 3N8WA 2W2QE 1L5GB 2UWLB 1EZQB 1HZ8A 4Y7AB 2BQ7A 2BO2A 2D1JB 2W2NE 4OTJA 5IKTA 5JB8E 2J94B 3NT1A 5CKQA 1HCGB 4CUEA 3LC3B 4RRYA 3GISX 3KRKA 4LMFA 2UWOB 3BT1A 3N8XA 5L2ZL 1V1HA 2VVCK 1FE2A 2Y81B
chains in the Genus database with same CATH topology
2BOHA 3CFWA 1NFXB 2VVUL 3SOQA 2BMGA 3FCSB 1GK5A 3HPTA 2VWNL 5COXA 2FLBL 1V3XB 3N8VA 2ADXA 3HS6A 1HT8A 3TZIA 4D0EA 3LN0A 3C9AC 4CUFA 1DVAL 1HAEA 1F0SB 2YGPA 2VVVL 2VH6B 4Y6DB 3BPSE 5IKVA 1NFYB 1IQLL 4A94C 4NGAL 1CVUA 1C5MF 1SZBA 1EBVA 1FSBA 1WHFA 5JB9E 2FLRL 2RA0L 3PGHA 3CS7L 5L2YL 2P95L 3M37L 2W2ME 2BOUA 3LN1A 2MHPA 4ISHL 1Z6EL 2KV4A 4JZFL 2WPKE 3GCXE 5JBAE 1F0RB 2J38B 1IOXA 2WPLE 2P3FL 3U73A 3MQEA 1PTHA 1ATEA 3V65B 3ELAL 3FBYA 1FF7A 4NG9L 3TH3L 3NTGA 2B7DL 3QCWA 5F19A 2XC0L 1IQKL 4ZXYL 2M74A 3POYA 1B9WA 2WPHE 1IQJL 2GD4A 5FDQA 3IITB 4X8VL 4OTYA 2I9BA 1TLEA 1IGZA 4JZDL 1UZJA 3M36L 4O02B 3BT2A 1MQ6L 1P0SL 1ZAQA 1APQA 1URKA 2P93L 2VWOL 4FM5A 1X7AL 5I46L 4RRZA 1G2MB 3LC5B 1J9CL 4JYVL 4Y71B 3RR3A 2P3UA 4MMYB 4ZH8B 5IKRA 2YGQA 2DDUA 1EPIA 4PH9A 4Y7BB 1K37A 2P16L 3F1SB 2W2PE 4D0FA 1YO8A 1FAXL 2W3IB 1O5DL 1WU1B 2NPRA 1JL9A 4Z0KB 2VH0B 2Y38A 1HREA 3DEMA 3KQDL 2H9EC 1OB1C 3TK6B 2WFXB 1IQHL 4X8UL 4BXSA 1HRFA 1UZPA 2WPIE 5CISA 1MQ5L 2XBXL 5L30L 1N7DA 1JV2B 3EGFA 1LPGA 4AQTA 2Q1JB 1IQEL 1G1SA 1KLJL 3FFGL 1QFKL 3SOVA 2KB9A 1PRHA 3HS5A 3KQBL 2VWLL 2P94L 3V64C 1COUA 1NQLB 1MOXC 4M10A 3ASIA 1XDTR 3ZYJB 1IP0A 2P28B 1A3PA 1UZQA 1I0UA 2F9BL 1NFWB 2WG4B 1APOA 2BQ6A 4D90A 2BOXA 1HT5A 1K36A 1CCVA 1YUKB 1IVOC 3QMOA 2WG3C 1PGEA 3OLTA 1IQIL 1EQHA 6COXA 1EMNA 1LPZA 3H5CB 1XKBA 2KL7A 4Z0LA 1EGFA 5KIRA 1RFNB 2Y5FL 2VWMK 2P3FN 2PUQL 2J2UB 2TGFA 2WFTA 5JW1A 3KQCL 1KIGL 4LORA 3R05A 1IJQA 1HX2A 1AUTL 4BTUA 3HS7A 3CENL 1HAFA 4NA9L 4BXWA 1JBUL 2WZPP 4RRXA 4MMXB 1F7MA 1LQDA 1NT0A 4TGFA 1CVWL 2Y7ZB 4BDXA 2OYEP 1TPGA 1PFXL 3Q3KB 4ZHAB 4RS0A 1IQFL 1W8BL 2J95B 1ATBA 1U67A 2FZZL 1WHEA 2H9EL 5E8DA 2K2TA 1EAIC 4Y79B 4CUDA 3LIWB 3TGFA 3N8WB 3HO5A 4M11A 1IGXA 3U7UG 2J34B 1TOZA 5CKMA 2KNIA 5JBBE 4G1MB 1FAKL 3NJPC 1DX5I 1DQBA 2Y7XB 2CJIB 2MGPA 5K0HB 1PXXA 2Y80B 2W86A 4Z6AL 3KL6B 2XC5L 4C16A 1UZKA 2W26B 2AYLA 2UWPB 3LAQA 1NFUB 4JYUL 1XKAL 3P5BL 5JVYA 1IOEL 1LMJA 1EPGA 1LPKA 1FFMA 1CCFA 1CEJA 3N8YB 2YGOA 5JVZA 1N1IA 3TBDA 5EGMB 2RNLA 4ZXXL 4COXA 2BOKL 3LTGD 3OLUA 1DIYA 1KLIL 3LTFB 1IQNL 4A7IA 1G1RA 2RHPA 2WYJB 3SW2A 5CKNA 2W3KB 2I9AA 2FLGA 1EPJA 1DDXA 3NTBA 1CX2A 2JKHL 4CSYA 3ZYIB 1YGCL 3N8YA 1U8CB 3SOBB 1Z6CA 3CA7A 4XLWA 2XC4L 1M1XB 2WPME 2OYUP 5IKQA 3ZYGA 4E1GA 1KSNB 1YUFA 1BF9A 1HJ7A 2EI7B 2XBWL 1NZIA 4RUTA 3KK6A 2XBVL 4YZUB 4BTTA 5KN5C 1L3YA 1F7EA 2PHBB 2WPJE 4XL1A 1Q4GA 2Y82B 1ATDA 2Y5HL 4ISIL 3HO3A 4Y76B 1CQEA 4BTIA 2BZ6L 3QH0A 4XBMA 2P26A 3HO4A 2EI8B 1P9JA 3KCGL 1G2LB 1G1TA 4RRWA 3S6XA 3F6UL 3IJEB 4JZEL 3ENSA 4YT7L 2P3TA 1ATAA 1G1QA 1LMMA 4O1ZA 5JBCE 2K2SB 1FJSL 2J4IB 1EMOA 3MDLA 4X8SL 1NPEB 2BQWA 2Y5GL 1KLOA 1YUGA 4X8TL 2XBYL 1IQML 2VJ3A 4YT6L 2FD6A 4MMZB 2MGRA 4ZAEB 2PR3B 1XFEA 1IQGL 1EQGA 1ADXA 2W2OE 3N8ZA 2EI6B 3GCWE 3TK5B 3K9XA 5F1AA 4BDWA 3KQEL 2WYGB 1EPHA 3Q7DA 1W7XL 2G00L 3N8WA 2W2QE 1L5GB 2UWLB 1EZQB 1HZ8A 4Y7AB 2BQ7A 2BO2A 2D1JB 2W2NE 4OTJA 5IKTA 5JB8E 2J94B 3NT1A 5CKQA 1HCGB 4CUEA 3LC3B 4RRYA 3GISX 3KRKA 4LMFA 2UWOB 3BT1A 3N8XA 5L2ZL 2VVCK 1FE2A 2Y81B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BOH A;  3CFW A;  1NFX B;  2VVU L;  3SOQ A;  2BMG A;  3FCS B;  1GK5 A;  3HPT A;  2VWN L;  5COX A;  2FLB L;  1V3X B;  3N8V A;  2ADX A;  3HS6 A;  1HT8 A;  3TZI A;  4D0E A;  3LN0 A;  3C9A C;  4CUF A;  1DVA L;  1HAE A;  1F0S B;  2YGP A;  2VVV L;  2VH6 B;  4Y6D B;  3BPS E;  5IKV A;  1NFY B;  1IQL L;  4NGA L;  1CVU A;  1C5M F;  1SZB A;  1EBV A;  1FSB A;  1WHF A;  5JB9 E;  2FLR L;  2RA0 L;  3PGH A;  3CS7 L;  5L2Y L;  2P95 L;  3M37 L;  2W2M E;  2BOU A;  3LN1 A;  2MHP A;  4ISH L;  1Z6E L;  2KV4 A;  4JZF L;  2WPK E;  3GCX E;  5JBA E;  1F0R B;  2J38 B;  1IOX A;  2WPL E;  2P3F L;  3U73 A;  3MQE A;  1PTH A;  1ATE A;  3V65 B;  3ELA L;  3FBY A;  1FF7 A;  4NG9 L;  3TH3 L;  3NTG A;  2B7D L;  3QCW A;  5F19 A;  2XC0 L;  1IQK L;  4ZXY L;  2M74 A;  3POY A;  1B9W A;  2WPH E;  1IQJ L;  2GD4 A;  5FDQ A;  3IIT B;  4X8V L;  4OTY A;  2I9B A;  1TLE A;  1IGZ A;  4JZD L;  1UZJ A;  3M36 L;  4O02 B;  3BT2 A;  1MQ6 L;  1P0S L;  1ZAQ A;  1APQ A;  1URK A;  2P93 L;  2VWO L;  4FM5 A;  1X7A L;  5I46 L;  4RRZ A;  1G2M B;  3LC5 B;  1J9C L;  4JYV L;  4Y71 B;  3RR3 A;  2P3U A;  4MMY B;  4ZH8 B;  5IKR A;  2DDU A;  1EPI A;  4PH9 A;  4Y7B B;  1K37 A;  2P16 L;  3F1S B;  2W2P E;  4D0F A;  1YO8 A;  1FAX L;  2W3I B;  1O5D L;  1WU1 B;  2NPR A;  1JL9 A;  4Z0K B;  2VH0 B;  2Y38 A;  1HRE A;  3DEM A;  3KQD L;  1OB1 C;  3TK6 B;  2WFX B;  1IQH L;  4X8U L;  4BXS A;  1HRF A;  1UZP A;  2WPI E;  5CIS A;  1MQ5 L;  2XBX L;  5L30 L;  1N7D A;  1JV2 B;  3EGF A;  1LPG A;  4AQT A;  2Q1J B;  1IQE L;  1G1S A;  1KLJ L;  3FFG L;  1QFK L;  3SOV A;  2KB9 A;  1PRH A;  3HS5 A;  3KQB L;  2VWL L;  2P94 L;  3V64 C;  1COU A;  1NQL B;  1MOX C;  4M10 A;  3ASI A;  1XDT R;  3ZYJ B;  1IP0 A;  2P28 B;  1A3P A;  1UZQ A;  1I0U A;  2F9B L;  1NFW B;  2WG4 B;  1APO A;  2BQ6 A;  4D90 A;  2BOX A;  1HT5 A;  1K36 A;  1CCV A;  1YUK B;  1IVO C;  3QMO A;  2WG3 C;  1PGE A;  3OLT A;  1IQI L;  1EQH A;  6COX A;  1EMN A;  1LPZ A;  3H5C B;  1XKB A;  2KL7 A;  4Z0L A;  1EGF A;  5KIR A;  1RFN B;  2Y5F L;  2VWM K;  2P3F N;  2PUQ L;  2J2U B;  2TGF A;  2WFT A;  5JW1 A;  3KQC L;  1KIG L;  4LOR A;  3R05 A;  1IJQ A;  1HX2 A;  1AUT L;  4BTU A;  3HS7 A;  3CEN L;  1HAF A;  4NA9 L;  4BXW A;  1JBU L;  4RRX A;  4MMX B;  1F7M A;  1LQD A;  1NT0 A;  4TGF A;  1CVW L;  2Y7Z B;  4BDX A;  2OYE P;  1TPG A;  1PFX L;  3Q3K B;  4ZHA B;  4RS0 A;  1IQF L;  1W8B L;  2J95 B;  1ATB A;  1U67 A;  2FZZ L;  1WHE A;  2H9E L;  5E8D A;  2K2T A;  1EAI C;  4Y79 B;  4CUD A;  3LIW B;  3TGF A;  3N8W B;  3HO5 A;  4M11 A;  1IGX A;  3U7U G;  2J34 B;  1TOZ A;  5CKM A;  5JBB E;  4G1M B;  1FAK L;  3NJP C;  1DX5 I;  1DQB A;  2Y7X B;  2CJI B;  2MGP A;  5K0H B;  1PXX A;  2Y80 B;  2W86 A;  4Z6A L;  3KL6 B;  2XC5 L;  4C16 A;  1UZK A;  2W26 B;  2AYL A;  2UWP B;  3LAQ A;  1NFU B;  4JYU L;  1XKA L;  3P5B L;  5JVY A;  1IOE L;  1LMJ A;  1EPG A;  1LPK A;  1FFM A;  1CCF A;  1CEJ A;  3N8Y B;  2YGO A;  5JVZ A;  1N1I A;  3TBD A;  5EGM B;  2RNL A;  4ZXX L;  4COX A;  2BOK L;  3LTG D;  3OLU A;  1DIY A;  1KLI L;  3LTF B;  1IQN L;  4A7I A;  1G1R A;  2RHP A;  2WYJ B;  3SW2 A;  5CKN A;  2W3K B;  2I9A A;  2FLG A;  1EPJ A;  1DDX A;  3NTB A;  1CX2 A;  2JKH L;  4CSY A;  3ZYI B;  1YGC L;  3N8Y A;  1U8C B;  3SOB B;  1Z6C A;  3CA7 A;  4XLW A;  2XC4 L;  1M1X B;  2WPM E;  2OYU P;  5IKQ A;  3ZYG A;  4E1G A;  1KSN B;  1YUF A;  1BF9 A;  1HJ7 A;  2EI7 B;  2XBW L;  1NZI A;  4RUT A;  3KK6 A;  2XBV L;  4YZU B;  4BTT A;  5KN5 C;  1L3Y A;  1F7E A;  2PHB B;  2WPJ E;  4XL1 A;  1Q4G A;  2Y82 B;  1ATD A;  2Y5H L;  4ISI L;  3HO3 A;  4Y76 B;  1CQE A;  4BTI A;  2BZ6 L;  3QH0 A;  4XBM A;  2P26 A;  3HO4 A;  2EI8 B;  1P9J A;  3KCG L;  1G2L B;  1G1T A;  4RRW A;  3F6U L;  3IJE B;  4JZE L;  3ENS A;  4YT7 L;  2P3T A;  1ATA A;  1G1Q A;  4O1Z A;  5JBC E;  2K2S B;  1FJS L;  2J4I B;  1EMO A;  3MDL A;  4X8S L;  1NPE B;  2BQW A;  2Y5G L;  1KLO A;  1YUG A;  4X8T L;  2XBY L;  1IQM L;  2VJ3 A;  4YT6 L;  2FD6 A;  4MMZ B;  2MGR A;  4ZAE B;  2PR3 B;  1XFE A;  1IQG L;  1EQG A;  1ADX A;  2W2O E;  3N8Z A;  2EI6 B;  3GCW E;  3TK5 B;  3K9X A;  5F1A A;  4BDW A;  3KQE L;  2WYG B;  1EPH A;  3Q7D A;  1W7X L;  2G00 L;  3N8W A;  2W2Q E;  1L5G B;  2UWL B;  1EZQ B;  1HZ8 A;  4Y7A B;  2BQ7 A;  2BO2 A;  2D1J B;  2W2N E;  4OTJ A;  5IKT A;  5JB8 E;  2J94 B;  3NT1 A;  5CKQ A;  1HCG B;  4CUE A;  3LC3 B;  4RRY A;  3GIS X;  3KRK A;  4LMF A;  2UWO B;  3BT1 A;  3N8X A;  5L2Z L;  2VVC K;  1FE2 A;  2Y81 B; 
#chains in the Genus database with same CATH topology
 2BOH A;  3CFW A;  1NFX B;  2VVU L;  3SOQ A;  2BMG A;  3FCS B;  1GK5 A;  3HPT A;  2VWN L;  5COX A;  2FLB L;  1V3X B;  3N8V A;  2ADX A;  3HS6 A;  1HT8 A;  3TZI A;  4D0E A;  3LN0 A;  3C9A C;  4CUF A;  1DVA L;  1HAE A;  1F0S B;  2YGP A;  2VVV L;  2VH6 B;  4Y6D B;  3BPS E;  5IKV A;  1NFY B;  1IQL L;  4A94 C;  4NGA L;  1CVU A;  1C5M F;  1SZB A;  1EBV A;  1FSB A;  1WHF A;  5JB9 E;  2FLR L;  2RA0 L;  3PGH A;  3CS7 L;  5L2Y L;  2P95 L;  3M37 L;  2W2M E;  2BOU A;  3LN1 A;  2MHP A;  4ISH L;  1Z6E L;  2KV4 A;  4JZF L;  2WPK E;  3GCX E;  5JBA E;  1F0R B;  2J38 B;  1IOX A;  2WPL E;  2P3F L;  3U73 A;  3MQE A;  1PTH A;  1ATE A;  3V65 B;  3ELA L;  3FBY A;  1FF7 A;  4NG9 L;  3TH3 L;  3NTG A;  2B7D L;  3QCW A;  2BSF A;  5F19 A;  2XC0 L;  1IQK L;  4ZXY L;  2M74 A;  3POY A;  1B9W A;  2WPH E;  1IQJ L;  2GD4 A;  5FDQ A;  3IIT B;  4X8V L;  4OTY A;  2I9B A;  1TLE A;  1IGZ A;  4JZD L;  1UZJ A;  3M36 L;  4O02 B;  3BT2 A;  1MQ6 L;  1P0S L;  1ZAQ A;  1APQ A;  1URK A;  2P93 L;  2VWO L;  4FM5 A;  1X7A L;  5I46 L;  4RRZ A;  1G2M B;  3LC5 B;  1J9C L;  4JYV L;  4Y71 B;  3RR3 A;  2P3U A;  4MMY B;  4ZH8 B;  5IKR A;  2YGQ A;  2DDU A;  1EPI A;  4PH9 A;  4Y7B B;  1K37 A;  2P16 L;  3F1S B;  2W2P E;  4D0F A;  1YO8 A;  1FAX L;  2W3I B;  1O5D L;  1WU1 B;  2NPR A;  1JL9 A;  4Z0K B;  2VH0 B;  2Y38 A;  1HRE A;  3DEM A;  3KQD L;  2H9E C;  1OB1 C;  1QIU A;  3TK6 B;  2WFX B;  1IQH L;  4X8U L;  4BXS A;  1HRF A;  1UZP A;  2VRS A;  2WPI E;  5CIS A;  1MQ5 L;  2XBX L;  5L30 L;  1N7D A;  1JV2 B;  3EGF A;  1LPG A;  4AQT A;  2Q1J B;  1IQE L;  1G1S A;  1KLJ L;  3FFG L;  1QFK L;  3SOV A;  2KB9 A;  1PRH A;  3HS5 A;  3KQB L;  2VWL L;  2P94 L;  3V64 C;  1COU A;  1NQL B;  1MOX C;  4M10 A;  3ASI A;  1XDT R;  3ZYJ B;  1IP0 A;  2P28 B;  1A3P A;  1UZQ A;  1I0U A;  2F9B L;  1NFW B;  2WG4 B;  1APO A;  2BQ6 A;  4D90 A;  2BOX A;  1HT5 A;  1K36 A;  1CCV A;  1YUK B;  1IVO C;  3QMO A;  2WG3 C;  1PGE A;  3OLT A;  1IQI L;  1EQH A;  6COX A;  1EMN A;  1LPZ A;  3H5C B;  1XKB A;  2KL7 A;  4Z0L A;  1EGF A;  5KIR A;  1RFN B;  2Y5F L;  2VWM K;  2P3F N;  2PUQ L;  2J2U B;  2TGF A;  2WFT A;  5JW1 A;  3KQC L;  1KIG L;  4LOR A;  3R05 A;  1IJQ A;  1HX2 A;  1AUT L;  4BTU A;  3HS7 A;  3CEN L;  1HAF A;  4NA9 L;  4BXW A;  1JBU L;  2WZP P;  2HOX A;  4RRX A;  4MMX B;  1F7M A;  1LQD A;  1NT0 A;  4TGF A;  1CVW L;  2Y7Z B;  4BDX A;  2OYE P;  2JJL A;  1TPG A;  1PFX L;  3Q3K B;  4ZHA B;  4RS0 A;  1IQF L;  1W8B L;  2J95 B;  1ATB A;  1U67 A;  2FZZ L;  1WHE A;  2H9E L;  5E8D A;  2K2T A;  1EAI C;  4Y79 B;  4CUD A;  3LIW B;  3TGF A;  3N8W B;  3HO5 A;  4M11 A;  1IGX A;  3U7U G;  2J34 B;  1TOZ A;  5CKM A;  2KNI A;  5JBB E;  4G1M B;  1FAK L;  3NJP C;  1DX5 I;  1DQB A;  2Y7X B;  2CJI B;  2MGP A;  5K0H B;  1PXX A;  2Y80 B;  2W86 A;  4Z6A L;  3KL6 B;  2XC5 L;  4C16 A;  1UZK A;  2W26 B;  2AYL A;  2UWP B;  3LAQ A;  1NFU B;  4JYU L;  1XKA L;  3P5B L;  5JVY A;  1IOE L;  1LMJ A;  1EPG A;  1LPK A;  1FFM A;  1CCF A;  1CEJ A;  3N8Y B;  2YGO A;  5JVZ A;  1N1I A;  3TBD A;  5EGM B;  2RNL A;  4ZXX L;  4COX A;  2BOK L;  3LTG D;  3OLU A;  1DIY A;  1KLI L;  3LTF B;  1IQN L;  4A7I A;  1G1R A;  2RHP A;  2WYJ B;  3SW2 A;  5CKN A;  2W3K B;  2I9A A;  2FLG A;  1EPJ A;  1DDX A;  3NTB A;  1CX2 A;  2JKH L;  4CSY A;  3ZYI B;  1YGC L;  3N8Y A;  1U8C B;  3SOB B;  1Z6C A;  3CA7 A;  4XLW A;  2XC4 L;  1M1X B;  2WPM E;  2OYU P;  5IKQ A;  3ZYG A;  4E1G A;  1KSN B;  1YUF A;  1BF9 A;  1HJ7 A;  2EI7 B;  2XBW L;  1NZI A;  4RUT A;  3KK6 A;  2XBV L;  4YZU B;  4BTT A;  5KN5 C;  1L3Y A;  1F7E A;  2PHB B;  2WPJ E;  4XL1 A;  1Q4G A;  2Y82 B;  1ATD A;  2Y5H L;  4ISI L;  3HO3 A;  4Y76 B;  1CQE A;  4BTI A;  2BZ6 L;  3QH0 A;  4XBM A;  2P26 A;  3HO4 A;  2EI8 B;  1P9J A;  3KCG L;  1G2L B;  1G1T A;  4RRW A;  3S6X A;  2BT7 A;  3F6U L;  3IJE B;  4JZE L;  3ENS A;  4YT7 L;  2P3T A;  1ATA A;  1G1Q A;  1LMM A;  4O1Z A;  5JBC E;  2K2S B;  1FJS L;  2J4I B;  1EMO A;  3MDL A;  4X8S L;  1NPE B;  2BQW A;  2Y5G L;  1KLO A;  1YUG A;  4X8T L;  2XBY L;  1IQM L;  2VJ3 A;  4YT6 L;  2FD6 A;  4MMZ B;  2MGR A;  4ZAE B;  1V1I A;  2PR3 B;  1XFE A;  1IQG L;  1KKE A;  1EQG A;  1ADX A;  2W2O E;  3N8Z A;  2EI6 B;  3GCW E;  2HOR A;  3TK5 B;  3K9X A;  5F1A A;  4BDW A;  1LK9 A;  3KQE L;  4GU3 A;  2WYG B;  4GU4 A;  1EPH A;  2BT8 A;  3Q7D A;  1W7X L;  2G00 L;  3N8W A;  2W2Q E;  1L5G B;  2UWL B;  1EZQ B;  1HZ8 A;  4Y7A B;  2BQ7 A;  2BO2 A;  2D1J B;  2W2N E;  4OTJ A;  5IKT A;  5JB8 E;  2J94 B;  3NT1 A;  5CKQ A;  1HCG B;  4CUE A;  3LC3 B;  4RRY A;  3GIS X;  3KRK A;  4LMF A;  2UWO B;  3BT1 A;  3N8X A;  5L2Z L;  1V1H A;  2VVC K;  1FE2 A;  2Y81 B; 
#chains in the Genus database with same CATH homology
 2BOH A;  3CFW A;  1NFX B;  2VVU L;  3SOQ A;  2BMG A;  3FCS B;  1GK5 A;  3HPT A;  2VWN L;  5COX A;  2FLB L;  1V3X B;  3N8V A;  2ADX A;  3HS6 A;  1HT8 A;  3TZI A;  4D0E A;  3LN0 A;  3C9A C;  4CUF A;  1DVA L;  1HAE A;  1F0S B;  2YGP A;  2VVV L;  2VH6 B;  4Y6D B;  3BPS E;  5IKV A;  1NFY B;  1IQL L;  4A94 C;  4NGA L;  1CVU A;  1C5M F;  1SZB A;  1EBV A;  1FSB A;  1WHF A;  5JB9 E;  2FLR L;  2RA0 L;  3PGH A;  3CS7 L;  5L2Y L;  2P95 L;  3M37 L;  2W2M E;  2BOU A;  3LN1 A;  2MHP A;  4ISH L;  1Z6E L;  2KV4 A;  4JZF L;  2WPK E;  3GCX E;  5JBA E;  1F0R B;  2J38 B;  1IOX A;  2WPL E;  2P3F L;  3U73 A;  3MQE A;  1PTH A;  1ATE A;  3V65 B;  3ELA L;  3FBY A;  1FF7 A;  4NG9 L;  3TH3 L;  3NTG A;  2B7D L;  3QCW A;  5F19 A;  2XC0 L;  1IQK L;  4ZXY L;  2M74 A;  3POY A;  1B9W A;  2WPH E;  1IQJ L;  2GD4 A;  5FDQ A;  3IIT B;  4X8V L;  4OTY A;  2I9B A;  1TLE A;  1IGZ A;  4JZD L;  1UZJ A;  3M36 L;  4O02 B;  3BT2 A;  1MQ6 L;  1P0S L;  1ZAQ A;  1APQ A;  1URK A;  2P93 L;  2VWO L;  4FM5 A;  1X7A L;  5I46 L;  4RRZ A;  1G2M B;  3LC5 B;  1J9C L;  4JYV L;  4Y71 B;  3RR3 A;  2P3U A;  4MMY B;  4ZH8 B;  5IKR A;  2YGQ A;  2DDU A;  1EPI A;  4PH9 A;  4Y7B B;  1K37 A;  2P16 L;  3F1S B;  2W2P E;  4D0F A;  1YO8 A;  1FAX L;  2W3I B;  1O5D L;  1WU1 B;  2NPR A;  1JL9 A;  4Z0K B;  2VH0 B;  2Y38 A;  1HRE A;  3DEM A;  3KQD L;  2H9E C;  1OB1 C;  3TK6 B;  2WFX B;  1IQH L;  4X8U L;  4BXS A;  1HRF A;  1UZP A;  2WPI E;  5CIS A;  1MQ5 L;  2XBX L;  5L30 L;  1N7D A;  1JV2 B;  3EGF A;  1LPG A;  4AQT A;  2Q1J B;  1IQE L;  1G1S A;  1KLJ L;  3FFG L;  1QFK L;  3SOV A;  2KB9 A;  1PRH A;  3HS5 A;  3KQB L;  2VWL L;  2P94 L;  3V64 C;  1COU A;  1NQL B;  1MOX C;  4M10 A;  3ASI A;  1XDT R;  3ZYJ B;  1IP0 A;  2P28 B;  1A3P A;  1UZQ A;  1I0U A;  2F9B L;  1NFW B;  2WG4 B;  1APO A;  2BQ6 A;  4D90 A;  2BOX A;  1HT5 A;  1K36 A;  1CCV A;  1YUK B;  1IVO C;  3QMO A;  2WG3 C;  1PGE A;  3OLT A;  1IQI L;  1EQH A;  6COX A;  1EMN A;  1LPZ A;  3H5C B;  1XKB A;  2KL7 A;  4Z0L A;  1EGF A;  5KIR A;  1RFN B;  2Y5F L;  2VWM K;  2P3F N;  2PUQ L;  2J2U B;  2TGF A;  2WFT A;  5JW1 A;  3KQC L;  1KIG L;  4LOR A;  3R05 A;  1IJQ A;  1HX2 A;  1AUT L;  4BTU A;  3HS7 A;  3CEN L;  1HAF A;  4NA9 L;  4BXW A;  1JBU L;  2WZP P;  4RRX A;  4MMX B;  1F7M A;  1LQD A;  1NT0 A;  4TGF A;  1CVW L;  2Y7Z B;  4BDX A;  2OYE P;  1TPG A;  1PFX L;  3Q3K B;  4ZHA B;  4RS0 A;  1IQF L;  1W8B L;  2J95 B;  1ATB A;  1U67 A;  2FZZ L;  1WHE A;  2H9E L;  5E8D A;  2K2T A;  1EAI C;  4Y79 B;  4CUD A;  3LIW B;  3TGF A;  3N8W B;  3HO5 A;  4M11 A;  1IGX A;  3U7U G;  2J34 B;  1TOZ A;  5CKM A;  2KNI A;  5JBB E;  4G1M B;  1FAK L;  3NJP C;  1DX5 I;  1DQB A;  2Y7X B;  2CJI B;  2MGP A;  5K0H B;  1PXX A;  2Y80 B;  2W86 A;  4Z6A L;  3KL6 B;  2XC5 L;  4C16 A;  1UZK A;  2W26 B;  2AYL A;  2UWP B;  3LAQ A;  1NFU B;  4JYU L;  1XKA L;  3P5B L;  5JVY A;  1IOE L;  1LMJ A;  1EPG A;  1LPK A;  1FFM A;  1CCF A;  1CEJ A;  3N8Y B;  2YGO A;  5JVZ A;  1N1I A;  3TBD A;  5EGM B;  2RNL A;  4ZXX L;  4COX A;  2BOK L;  3LTG D;  3OLU A;  1DIY A;  1KLI L;  3LTF B;  1IQN L;  4A7I A;  1G1R A;  2RHP A;  2WYJ B;  3SW2 A;  5CKN A;  2W3K B;  2I9A A;  2FLG A;  1EPJ A;  1DDX A;  3NTB A;  1CX2 A;  2JKH L;  4CSY A;  3ZYI B;  1YGC L;  3N8Y A;  1U8C B;  3SOB B;  1Z6C A;  3CA7 A;  4XLW A;  2XC4 L;  1M1X B;  2WPM E;  2OYU P;  5IKQ A;  3ZYG A;  4E1G A;  1KSN B;  1YUF A;  1BF9 A;  1HJ7 A;  2EI7 B;  2XBW L;  1NZI A;  4RUT A;  3KK6 A;  2XBV L;  4YZU B;  4BTT A;  5KN5 C;  1L3Y A;  1F7E A;  2PHB B;  2WPJ E;  4XL1 A;  1Q4G A;  2Y82 B;  1ATD A;  2Y5H L;  4ISI L;  3HO3 A;  4Y76 B;  1CQE A;  4BTI A;  2BZ6 L;  3QH0 A;  4XBM A;  2P26 A;  3HO4 A;  2EI8 B;  1P9J A;  3KCG L;  1G2L B;  1G1T A;  4RRW A;  3S6X A;  3F6U L;  3IJE B;  4JZE L;  3ENS A;  4YT7 L;  2P3T A;  1ATA A;  1G1Q A;  1LMM A;  4O1Z A;  5JBC E;  2K2S B;  1FJS L;  2J4I B;  1EMO A;  3MDL A;  4X8S L;  1NPE B;  2BQW A;  2Y5G L;  1KLO A;  1YUG A;  4X8T L;  2XBY L;  1IQM L;  2VJ3 A;  4YT6 L;  2FD6 A;  4MMZ B;  2MGR A;  4ZAE B;  2PR3 B;  1XFE A;  1IQG L;  1EQG A;  1ADX A;  2W2O E;  3N8Z A;  2EI6 B;  3GCW E;  3TK5 B;  3K9X A;  5F1A A;  4BDW A;  3KQE L;  2WYG B;  1EPH A;  3Q7D A;  1W7X L;  2G00 L;  3N8W A;  2W2Q E;  1L5G B;  2UWL B;  1EZQ B;  1HZ8 A;  4Y7A B;  2BQ7 A;  2BO2 A;  2D1J B;  2W2N E;  4OTJ A;  5IKT A;  5JB8 E;  2J94 B;  3NT1 A;  5CKQ A;  1HCG B;  4CUE A;  3LC3 B;  4RRY A;  3GIS X;  3KRK A;  4LMF A;  2UWO B;  3BT1 A;  3N8X A;  5L2Z L;  2VVC K;  1FE2 A;  2Y81 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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