3Q3KB

Factor xa in complex with a phenylenediamine derivative
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
52
structure length
52
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design, synthesis and SAR of novel ethylenediamine and phenylenediamine derivatives as factor Xa inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Activated factor Xa heavy chain
total genus 12
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2010-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3q3kB00
1HREA 4PH9A 5E8DA 2BO2A 2YGOA 2P93L 2VWMK 3HS5A 3CFWA 2Y5GL 4Y6DB 1GK5A 2EI8B 2KL7A 4ZHAB 1HCGB 1DIYA 1HT8A 3HO5A 1K36A 4C16A 2UWLB 1ATBA 5I46L 4MMXB 1KIGL 2Y5HL 3CS7L 1F7MA 2W2NE 4O1ZA 4LORA 2W26B 4D0EA 2YGPA 1OB1C 4BTUA 1JBUL 3POYA 4BTIA 1IQML 5FDQA 1B9WA 1HAEA 3MDLA 1AUTL 5JB9E 5IKVA 2VVVL 2BQ7A 2F9BL 2WPIE 2RHPA 3FCSB 1A3PA 2D1JB 1CEJA 3HS6A 3RR3A 2Y80B 2FLBL 2BZ6L 3LC5B 3KCGL 3ZYJB 1DX5I 4AQTA 1J9CL 3N8ZA 1EZQB 3KQCL 2J4IB 3BPSE 2CJIB 3KL6B 2Y5FL 1FAXL 3N8WA 1MQ5L 3NT1A 4BXSA 1P9JA 1EBVA 3H5CB 2J2UB 1EPHA 3FBYA 3KRKA 1EMOA 1ZAQA 3V64C 1G1TA 4M11A 1Z6EL 2TGFA 1UZJA 2W2OE 1G2LB 1FF7A 1NFWB 1PFXL 1X7AL 2P3FL 1HJ7A 3R05A 1IGZA 2I9BA 1IQKL 2VH6B 1IQIL 2P3UA 1EPJA 1PRHA 1KLOA 3N8WB 1NFYB 2EI7B 5L2ZL 1L5GB 1IQLL 2OYUP 2WFTA 1JV2B 3MQEA 2MGPA 1G2MB 2AYLA 3ZYIB 2Q1JB 4Y79B 3LTGD 1G1RA 1NFXB 4Z0KB 1IQEL 2P95L 4X8VL 3TK5B 1CQEA 1Q4GA 6COXA 1FJSL 4NGAL 3GISX 1HZ8A 1CVWL 4CSYA 3TZIA 1EPGA 1WHEA 3HO3A 1KLJL 1IOEL 1YO8A 2WG4B 4ZAEB 1EQGA 4RRYA 1WHFA 1KSNB 1ATEA 2FLRL 1O5DL 1HT5A 1U67A 2MHPA 3NJPC 2BOHA 4CUFA 1COUA 2W3IB 4NA9L 1DVAL 4MMZB 1EQHA 1NPEB 4LMFA 2WPHE 4O02B 5KIRA 2VWNL 3LN1A 2WPKE 5L30L 2NPRA 2P94L 2P3TA 4RRXA 1DQBA 2VH0B 3TK6B 4A7IA 5JVYA 1F0RB 3M37L 3IITB 3C9AC 5JW1A 1TPGA 3HS7A 3CENL 2VWOL 1ADXA 1EAIC 4RS0A 2UWOB 4Y7BB 4BDWA 3U73A 5COXA 2W86A 3BT2A 2FLGA 3N8VA 4CUEA 3DEMA 2Y7XB 2W3KB 1LPZA 3TGFA 5F1AA 2P16L 1TLEA 1IVOC 4BTTA 4X8TL 3OLUA 2WG3C 2J34B 3Q3KB 3M36L 2P3FN 3PGHA 1IQNL 4COXA 3SOBB 1JL9A 3CA7A 1Z6CA 2OYEP 1QFKL 2VWLL 2P26A 4G1MB 1TOZA 5CKNA 2RNLA 4OTYA 2Y7ZB 3OLTA 2Y38A 2DDUA 4M10A 2VVUL 1YUGA 1LQDA 5CISA 3LC3B 3NTBA 1F0SB 3N8YA 2J94B 5JB8E 2M74A 1NT0A 3LTFB 2XC4L 3F6UL 1PXXA 5IKRA 2G00L 1PGEA 3KQDL 1IP0A 4XBMA 2WPLE 1IQHL 2XBWL 1UZPA 3SOVA 2BQ6A 1EMNA 3U7UG 2J38B 1CVUA 4D90A 3Q7DA 2XBXL 5JBBE 1MQ6L 1P0SL 1W7XL 1M1XB 2MGRA 3K9XA 3HPTA 3LN0A 3TH3L 5IKTA 1IQFL 2KB9A 3P5BL 1ATDA 2EI6B 3N8YB 3LAQA 2PR3B 2BOXA 1FAKL 1N7DA 2BOKL 1L3YA 1IGXA 2UWPB 2XBVL 3SW2A 2PHBB 2W2QE 1UZQA 2XC0L 2B7DL 1IJQA 2RA0L 4D0FA 3QH0A 1CCFA 1CX2A 1IOXA 3QCWA 4FM5A 1U8CB 3ASIA 1LPGA 1CCVA 1YUFA 1W8BL 1EPIA 2WYGB 1FE2A 1HRFA 1WU1B 3EGFA 1XKAL 1EGFA 5EGMB 2K2TA 1XDTR 3SOQA 1HX2A 4JYVL 4ZXXL 5L2YL 3NTGA 4RUTA 4ZH8B 2XBYL 4XL1A 1MOXC 5F19A 5K0HB 1IQJL 4YZUB 4ISHL 2FD6A 5JBAE 3F1SB 4RRZA 4Z0LA 1F7EA 2BQWA 4JZFL 1C5MF 1BF9A 2WPJE 4X8SL 4TGFA 1FSBA 2PUQL 4ISIL 4Y7AB 2P28B 3KK6A 4BXWA 2I9AA 2W2PE 1NQLB 1UZKA 1V3XB 2WYJB 2BOUA 2WFXB 3LIWB 3V65B 5CKMA 5IKQA 2Y82B 3GCWE 5KN5C 3IJEB 2KV4A 1RFNB 3BT1A 3HO4A 1LMJA 1NZIA 1YUKB 1URKA 2W2ME 1K37A 2H9EL 1FFMA 2ADXA 2FZZL 3ENSA 1HAFA 3QMOA 2Y81B 1I0UA 1XKBA 4NG9L 3TBDA 3KQEL 2BMGA 1PTHA 1ATAA 1LPKA 3GCXE 1G1QA 1IQGL 3ELAL 3N8XA 4JYUL 4Y76B 2VJ3A 4ZXYL 2JKHL 4OTJA 3ZYGA 1YGCL 2K2SB 2VVCK 5JVZA 2XC5L 4BDXA 4CUDA 3KQBL 1APQA 3FFGL 5JBCE 4RRWA 4Y71B 4MMYB 4YT6L 4E1GA 4JZDL 2WPME 4JZEL 1NFUB 1DDXA 1APOA 4X8UL 4Z6AL 1KLIL 1SZBA 5CKQA 1N1IA 2J95B 2GD4A 1G1SA 4YT7L 1XFEA 4XLWA
chains in the Genus database with same CATH superfamily
1HREA 4PH9A 5E8DA 2BO2A 2YGOA 2P93L 2VWMK 3HS5A 3CFWA 2Y5GL 4Y6DB 1GK5A 2EI8B 2KL7A 4ZHAB 1HCGB 1DIYA 1HT8A 2KNIA 3HO5A 1K36A 4C16A 2UWLB 1ATBA 5I46L 4MMXB 1KIGL 2Y5HL 3CS7L 1F7MA 2W2NE 4O1ZA 4LORA 2W26B 4D0EA 2YGPA 1OB1C 4BTUA 1JBUL 3POYA 4BTIA 1IQML 5FDQA 1B9WA 1HAEA 3MDLA 1AUTL 2HOXA 5JB9E 5IKVA 2VVVL 2BQ7A 2F9BL 2WPIE 2WZPP 2RHPA 3FCSB 1A3PA 2D1JB 1CEJA 3HS6A 3RR3A 2Y80B 2FLBL 2BZ6L 3LC5B 3KCGL 3ZYJB 1DX5I 4AQTA 1J9CL 3N8ZA 1EZQB 3KQCL 3BPSE 2J4IB 2CJIB 3KL6B 2Y5FL 1FAXL 3N8WA 1MQ5L 3NT1A 4BXSA 1P9JA 1EBVA 3H5CB 2J2UB 1EPHA 3FBYA 3KRKA 1EMOA 1ZAQA 3V64C 1G1TA 4M11A 1Z6EL 2TGFA 1UZJA 2W2OE 1G2LB 1FF7A 1NFWB 1PFXL 1X7AL 2P3FL 1HJ7A 3R05A 1IGZA 2I9BA 1IQKL 1V1IA 2VH6B 1IQIL 2P3UA 1EPJA 1PRHA 3S6XA 1KLOA 3N8WB 1NFYB 2EI7B 5L2ZL 1L5GB 1IQLL 2OYUP 2WFTA 1JV2B 3MQEA 2MGPA 1G2MB 2AYLA 3ZYIB 2Q1JB 4Y79B 3LTGD 1G1RA 1NFXB 4Z0KB 1IQEL 2P95L 4X8VL 3TK5B 1CQEA 1Q4GA 6COXA 1FJSL 4NGAL 3GISX 1HZ8A 1CVWL 4CSYA 3TZIA 1EPGA 1WHEA 3HO3A 1KLJL 1IOEL 1YO8A 2WG4B 4ZAEB 1EQGA 4RRYA 1WHFA 1KSNB 1ATEA 2FLRL 1O5DL 1HT5A 1U67A 2MHPA 3NJPC 2BOHA 4CUFA 1COUA 1V1HA 2JJLA 2W3IB 4NA9L 1DVAL 4MMZB 1EQHA 1NPEB 4LMFA 2WPHE 4O02B 5KIRA 2VWNL 3LN1A 2WPKE 5L30L 2NPRA 2P94L 2P3TA 4GU3A 4RRXA 1DQBA 2VH0B 3TK6B 4A7IA 5JVYA 1F0RB 3M37L 3IITB 3C9AC 5JW1A 1TPGA 3HS7A 3CENL 2VWOL 1LK9A 1ADXA 1EAIC 4RS0A 2UWOB 4Y7BB 4BDWA 3U73A 5COXA 2W86A 3BT2A 2FLGA 3N8VA 4CUEA 3DEMA 2Y7XB 2BT7A 2W3KB 1LPZA 3TGFA 5F1AA 2P16L 1TLEA 1IVOC 4BTTA 4X8TL 3OLUA 2WG3C 2J34B 3Q3KB 3M36L 2P3FN 3PGHA 1IQNL 4COXA 3SOBB 1JL9A 3CA7A 1Z6CA 2OYEP 1QFKL 2VWLL 2P26A 4G1MB 1TOZA 5CKNA 2VRSA 2RNLA 4OTYA 2Y7ZB 3OLTA 4A94C 2Y38A 2DDUA 4M10A 4GU4A 1KKEA 1YUGA 2VVUL 1LQDA 5CISA 3LC3B 3NTBA 1F0SB 3N8YA 2J94B 5JB8E 2M74A 2HORA 1NT0A 3LTFB 2XC4L 3F6UL 1PXXA 5IKRA 2G00L 1PGEA 3KQDL 1IP0A 4XBMA 2WPLE 1IQHL 2XBWL 1UZPA 3SOVA 2BQ6A 1EMNA 3U7UG 2J38B 1CVUA 4D90A 3Q7DA 2XBXL 5JBBE 1MQ6L 1P0SL 1W7XL 1M1XB 2MGRA 3K9XA 3HPTA 3LN0A 3TH3L 5IKTA 1IQFL 2KB9A 3P5BL 1ATDA 2EI6B 3N8YB 3LAQA 2PR3B 2BOXA 1FAKL 1N7DA 2BOKL 2H9EC 1L3YA 1IGXA 2UWPB 2XBVL 3SW2A 2PHBB 2W2QE 1UZQA 2XC0L 2B7DL 1IJQA 2RA0L 4D0FA 3QH0A 1CCFA 1CX2A 1IOXA 3QCWA 4FM5A 1U8CB 3ASIA 1LPGA 1CCVA 1YUFA 1W8BL 1EPIA 2WYGB 1FE2A 1HRFA 1WU1B 3EGFA 1XKAL 1EGFA 5EGMB 2K2TA 1XDTR 3SOQA 1HX2A 4JYVL 4ZXXL 5L2YL 3NTGA 4RUTA 4ZH8B 2XBYL 4XL1A 1MOXC 5F19A 5K0HB 1IQJL 2BT8A 4YZUB 4ISHL 2FD6A 5JBAE 3F1SB 4RRZA 4Z0LA 1F7EA 2BQWA 4JZFL 1C5MF 1BF9A 2WPJE 4X8SL 4TGFA 1FSBA 2PUQL 4ISIL 4Y7AB 2P28B 3KK6A 4BXWA 2I9AA 2W2PE 1NQLB 1UZKA 1V3XB 2WYJB 2BOUA 2WFXB 3LIWB 3V65B 5CKMA 5IKQA 2Y82B 2YGQA 3GCWE 5KN5C 3IJEB 2KV4A 1RFNB 3BT1A 3HO4A 1LMJA 1NZIA 1QIUA 1YUKB 1URKA 2W2ME 2BSFA 1K37A 2H9EL 1FFMA 2ADXA 2FZZL 3ENSA 1HAFA 3QMOA 2Y81B 1I0UA 1XKBA 4NG9L 3TBDA 3KQEL 2BMGA 1PTHA 1ATAA 1LPKA 3GCXE 1G1QA 1IQGL 3ELAL 3N8XA 4JYUL 4Y76B 2VJ3A 4ZXYL 2JKHL 4OTJA 3ZYGA 1YGCL 2K2SB 2VVCK 5JVZA 2XC5L 4BDXA 4CUDA 3KQBL 1APQA 3FFGL 5JBCE 4RRWA 4Y71B 4MMYB 4YT6L 4E1GA 4JZDL 2WPME 4JZEL 1NFUB 1DDXA 1APOA 4X8UL 4Z6AL 1KLIL 1SZBA 5CKQA 1N1IA 1LMMA 2J95B 2GD4A 1G1SA 4YT7L 1XFEA 4XLWA
chains in the Genus database with same CATH topology
1HREA 4PH9A 5E8DA 2BO2A 2YGOA 2P93L 2VWMK 3HS5A 3CFWA 2Y5GL 4Y6DB 1GK5A 2EI8B 2KL7A 4ZHAB 1HCGB 1DIYA 1HT8A 2KNIA 3HO5A 1K36A 4C16A 2UWLB 1ATBA 5I46L 4MMXB 1KIGL 2Y5HL 3CS7L 1F7MA 2W2NE 4O1ZA 4LORA 2W26B 4D0EA 2YGPA 1OB1C 4BTUA 1JBUL 3POYA 4BTIA 1IQML 5FDQA 1B9WA 1HAEA 3MDLA 1AUTL 5JB9E 5IKVA 2VVVL 2BQ7A 2F9BL 2WPIE 2WZPP 2RHPA 3FCSB 1A3PA 2D1JB 1CEJA 3HS6A 3RR3A 2Y80B 2FLBL 2BZ6L 3LC5B 3KCGL 3ZYJB 1DX5I 4AQTA 1J9CL 3N8ZA 1EZQB 3KQCL 2J4IB 3BPSE 2CJIB 3KL6B 2Y5FL 1FAXL 3N8WA 1MQ5L 3NT1A 4BXSA 1P9JA 1EBVA 3H5CB 2J2UB 1EPHA 3FBYA 3KRKA 1EMOA 1ZAQA 3V64C 1G1TA 4M11A 1Z6EL 2TGFA 1UZJA 2W2OE 1G2LB 1FF7A 1NFWB 1PFXL 1X7AL 2P3FL 1HJ7A 3R05A 1IGZA 2I9BA 1IQKL 2VH6B 1IQIL 2P3UA 1EPJA 1PRHA 3S6XA 1KLOA 3N8WB 1NFYB 2EI7B 5L2ZL 1L5GB 1IQLL 2OYUP 2WFTA 1JV2B 3MQEA 2MGPA 1G2MB 2AYLA 3ZYIB 2Q1JB 4Y79B 3LTGD 1G1RA 1NFXB 4Z0KB 1IQEL 2P95L 4X8VL 3TK5B 1CQEA 1Q4GA 6COXA 1FJSL 4NGAL 3GISX 1HZ8A 1CVWL 4CSYA 3TZIA 1EPGA 1WHEA 3HO3A 1KLJL 1IOEL 1YO8A 2WG4B 4ZAEB 1EQGA 4RRYA 1WHFA 1KSNB 1ATEA 2FLRL 1O5DL 1HT5A 1U67A 2MHPA 3NJPC 2BOHA 4CUFA 1COUA 2W3IB 4NA9L 1DVAL 4MMZB 1EQHA 1NPEB 4LMFA 2WPHE 4O02B 5KIRA 2VWNL 3LN1A 2WPKE 5L30L 2NPRA 2P94L 2P3TA 4RRXA 1DQBA 2VH0B 3TK6B 4A7IA 5JVYA 1F0RB 3M37L 3IITB 3C9AC 5JW1A 1TPGA 3HS7A 3CENL 2VWOL 1ADXA 1EAIC 4RS0A 2UWOB 4Y7BB 4BDWA 3U73A 5COXA 2W86A 3BT2A 2FLGA 3N8VA 4CUEA 3DEMA 2Y7XB 2W3KB 1LPZA 3TGFA 5F1AA 2P16L 1TLEA 1IVOC 4BTTA 4X8TL 3OLUA 2WG3C 2J34B 3Q3KB 3M36L 2P3FN 3PGHA 1IQNL 4COXA 3SOBB 1JL9A 3CA7A 1Z6CA 2OYEP 1QFKL 2VWLL 2P26A 4G1MB 1TOZA 5CKNA 2RNLA 4OTYA 2Y7ZB 3OLTA 4A94C 2Y38A 2DDUA 4M10A 2VVUL 1YUGA 1LQDA 5CISA 3LC3B 3NTBA 1F0SB 3N8YA 2J94B 5JB8E 2M74A 1NT0A 3LTFB 2XC4L 3F6UL 1PXXA 5IKRA 2G00L 1PGEA 3KQDL 1IP0A 4XBMA 2WPLE 1IQHL 2XBWL 1UZPA 3SOVA 2BQ6A 1EMNA 3U7UG 2J38B 1CVUA 4D90A 3Q7DA 2XBXL 5JBBE 1MQ6L 1P0SL 1W7XL 1M1XB 2MGRA 3K9XA 3HPTA 3LN0A 3TH3L 5IKTA 1IQFL 2KB9A 3P5BL 1ATDA 2EI6B 3N8YB 3LAQA 2PR3B 2BOXA 1FAKL 1N7DA 2BOKL 2H9EC 1L3YA 1IGXA 2UWPB 2XBVL 3SW2A 2PHBB 2W2QE 1UZQA 2XC0L 2B7DL 1IJQA 2RA0L 4D0FA 3QH0A 1CCFA 1CX2A 1IOXA 3QCWA 4FM5A 1U8CB 3ASIA 1LPGA 1CCVA 1YUFA 1W8BL 1EPIA 2WYGB 1FE2A 1HRFA 1WU1B 3EGFA 1XKAL 1EGFA 5EGMB 2K2TA 1XDTR 3SOQA 1HX2A 4JYVL 4ZXXL 5L2YL 3NTGA 4RUTA 4ZH8B 2XBYL 4XL1A 1MOXC 5F19A 5K0HB 1IQJL 4YZUB 4ISHL 2FD6A 5JBAE 3F1SB 4RRZA 4Z0LA 1F7EA 2BQWA 4JZFL 1C5MF 1BF9A 2WPJE 4X8SL 4TGFA 1FSBA 2PUQL 4ISIL 4Y7AB 2P28B 3KK6A 4BXWA 2I9AA 2W2PE 1NQLB 1UZKA 1V3XB 2WYJB 2BOUA 2WFXB 3LIWB 3V65B 5CKMA 5IKQA 2Y82B 2YGQA 3GCWE 5KN5C 3IJEB 2KV4A 1RFNB 3BT1A 3HO4A 1LMJA 1NZIA 1YUKB 1URKA 2W2ME 1K37A 2H9EL 1FFMA 2ADXA 2FZZL 3ENSA 1HAFA 3QMOA 2Y81B 1I0UA 1XKBA 4NG9L 3TBDA 3KQEL 2BMGA 1PTHA 1ATAA 1LPKA 3GCXE 1G1QA 1IQGL 3ELAL 3N8XA 4JYUL 4Y76B 2VJ3A 4ZXYL 2JKHL 4OTJA 3ZYGA 1YGCL 2K2SB 2VVCK 5JVZA 2XC5L 4BDXA 4CUDA 3KQBL 1APQA 3FFGL 5JBCE 4RRWA 4Y71B 4MMYB 4YT6L 4E1GA 4JZDL 2WPME 4JZEL 1NFUB 1DDXA 1APOA 4X8UL 4Z6AL 1KLIL 1SZBA 5CKQA 1N1IA 1LMMA 2J95B 2GD4A 1G1SA 4YT7L 1XFEA 4XLWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HRE A;  4PH9 A;  5E8D A;  2BO2 A;  2YGO A;  2P93 L;  2VWM K;  3HS5 A;  3CFW A;  2Y5G L;  4Y6D B;  1GK5 A;  2EI8 B;  2KL7 A;  4ZHA B;  1HCG B;  1DIY A;  1HT8 A;  3HO5 A;  1K36 A;  4C16 A;  2UWL B;  1ATB A;  5I46 L;  4MMX B;  1KIG L;  2Y5H L;  3CS7 L;  1F7M A;  2W2N E;  4O1Z A;  4LOR A;  2W26 B;  4D0E A;  2YGP A;  1OB1 C;  4BTU A;  1JBU L;  3POY A;  4BTI A;  1IQM L;  5FDQ A;  1B9W A;  1HAE A;  3MDL A;  1AUT L;  5JB9 E;  5IKV A;  2VVV L;  2BQ7 A;  2F9B L;  2WPI E;  2RHP A;  3FCS B;  1A3P A;  2D1J B;  1CEJ A;  3HS6 A;  3RR3 A;  2Y80 B;  2FLB L;  2BZ6 L;  3LC5 B;  3KCG L;  3ZYJ B;  1DX5 I;  4AQT A;  1J9C L;  3N8Z A;  1EZQ B;  3KQC L;  2J4I B;  3BPS E;  2CJI B;  3KL6 B;  2Y5F L;  1FAX L;  3N8W A;  1MQ5 L;  3NT1 A;  4BXS A;  1P9J A;  1EBV A;  3H5C B;  2J2U B;  1EPH A;  3FBY A;  3KRK A;  1EMO A;  1ZAQ A;  3V64 C;  1G1T A;  4M11 A;  1Z6E L;  2TGF A;  1UZJ A;  2W2O E;  1G2L B;  1FF7 A;  1NFW B;  1PFX L;  1X7A L;  2P3F L;  1HJ7 A;  3R05 A;  1IGZ A;  2I9B A;  1IQK L;  2VH6 B;  1IQI L;  2P3U A;  1EPJ A;  1PRH A;  1KLO A;  3N8W B;  1NFY B;  2EI7 B;  5L2Z L;  1L5G B;  1IQL L;  2OYU P;  2WFT A;  1JV2 B;  3MQE A;  2MGP A;  1G2M B;  2AYL A;  3ZYI B;  2Q1J B;  4Y79 B;  3LTG D;  1G1R A;  1NFX B;  4Z0K B;  1IQE L;  2P95 L;  4X8V L;  3TK5 B;  1CQE A;  1Q4G A;  6COX A;  1FJS L;  4NGA L;  3GIS X;  1HZ8 A;  1CVW L;  4CSY A;  3TZI A;  1EPG A;  1WHE A;  3HO3 A;  1KLJ L;  1IOE L;  1YO8 A;  2WG4 B;  4ZAE B;  1EQG A;  4RRY A;  1WHF A;  1KSN B;  1ATE A;  2FLR L;  1O5D L;  1HT5 A;  1U67 A;  2MHP A;  3NJP C;  2BOH A;  4CUF A;  1COU A;  2W3I B;  4NA9 L;  1DVA L;  4MMZ B;  1EQH A;  1NPE B;  4LMF A;  2WPH E;  4O02 B;  5KIR A;  2VWN L;  3LN1 A;  2WPK E;  5L30 L;  2NPR A;  2P94 L;  2P3T A;  4RRX A;  1DQB A;  2VH0 B;  3TK6 B;  4A7I A;  5JVY A;  1F0R B;  3M37 L;  3IIT B;  3C9A C;  5JW1 A;  1TPG A;  3HS7 A;  3CEN L;  2VWO L;  1ADX A;  1EAI C;  4RS0 A;  2UWO B;  4Y7B B;  4BDW A;  3U73 A;  5COX A;  2W86 A;  3BT2 A;  2FLG A;  3N8V A;  4CUE A;  3DEM A;  2Y7X B;  2W3K B;  1LPZ A;  3TGF A;  5F1A A;  2P16 L;  1TLE A;  1IVO C;  4BTT A;  4X8T L;  3OLU A;  2WG3 C;  2J34 B;  3Q3K B;  3M36 L;  2P3F N;  3PGH A;  1IQN L;  4COX A;  3SOB B;  1JL9 A;  3CA7 A;  1Z6C A;  2OYE P;  1QFK L;  2VWL L;  2P26 A;  4G1M B;  1TOZ A;  5CKN A;  2RNL A;  4OTY A;  2Y7Z B;  3OLT A;  2Y38 A;  2DDU A;  4M10 A;  2VVU L;  1YUG A;  1LQD A;  5CIS A;  3LC3 B;  3NTB A;  1F0S B;  3N8Y A;  2J94 B;  5JB8 E;  2M74 A;  1NT0 A;  3LTF B;  2XC4 L;  3F6U L;  1PXX A;  5IKR A;  2G00 L;  1PGE A;  3KQD L;  1IP0 A;  4XBM A;  2WPL E;  1IQH L;  2XBW L;  1UZP A;  3SOV A;  2BQ6 A;  1EMN A;  3U7U G;  2J38 B;  1CVU A;  4D90 A;  3Q7D A;  2XBX L;  5JBB E;  1MQ6 L;  1P0S L;  1W7X L;  1M1X B;  2MGR A;  3K9X A;  3HPT A;  3LN0 A;  3TH3 L;  5IKT A;  1IQF L;  2KB9 A;  3P5B L;  1ATD A;  2EI6 B;  3N8Y B;  3LAQ A;  2PR3 B;  2BOX A;  1FAK L;  1N7D A;  2BOK L;  1L3Y A;  1IGX A;  2UWP B;  2XBV L;  3SW2 A;  2PHB B;  2W2Q E;  1UZQ A;  2XC0 L;  2B7D L;  1IJQ A;  2RA0 L;  4D0F A;  3QH0 A;  1CCF A;  1CX2 A;  1IOX A;  3QCW A;  4FM5 A;  1U8C B;  3ASI A;  1LPG A;  1CCV A;  1YUF A;  1W8B L;  1EPI A;  2WYG B;  1FE2 A;  1HRF A;  1WU1 B;  3EGF A;  1XKA L;  1EGF A;  5EGM B;  2K2T A;  1XDT R;  3SOQ A;  1HX2 A;  4JYV L;  4ZXX L;  5L2Y L;  3NTG A;  4RUT A;  4ZH8 B;  2XBY L;  4XL1 A;  1MOX C;  5F19 A;  5K0H B;  1IQJ L;  4YZU B;  4ISH L;  2FD6 A;  5JBA E;  3F1S B;  4RRZ A;  4Z0L A;  1F7E A;  2BQW A;  4JZF L;  1C5M F;  1BF9 A;  2WPJ E;  4X8S L;  4TGF A;  1FSB A;  2PUQ L;  4ISI L;  4Y7A B;  2P28 B;  3KK6 A;  4BXW A;  2I9A A;  2W2P E;  1NQL B;  1UZK A;  1V3X B;  2WYJ B;  2BOU A;  2WFX B;  3LIW B;  3V65 B;  5CKM A;  5IKQ A;  2Y82 B;  3GCW E;  5KN5 C;  3IJE B;  2KV4 A;  1RFN B;  3BT1 A;  3HO4 A;  1LMJ A;  1NZI A;  1YUK B;  1URK A;  2W2M E;  1K37 A;  2H9E L;  1FFM A;  2ADX A;  2FZZ L;  3ENS A;  1HAF A;  3QMO A;  2Y81 B;  1I0U A;  1XKB A;  4NG9 L;  3TBD A;  3KQE L;  2BMG A;  1PTH A;  1ATA A;  1LPK A;  3GCX E;  1G1Q A;  1IQG L;  3ELA L;  3N8X A;  4JYU L;  4Y76 B;  2VJ3 A;  4ZXY L;  2JKH L;  4OTJ A;  3ZYG A;  1YGC L;  2K2S B;  2VVC K;  5JVZ A;  2XC5 L;  4BDX A;  4CUD A;  3KQB L;  1APQ A;  3FFG L;  5JBC E;  4RRW A;  4Y71 B;  4MMY B;  4YT6 L;  4E1G A;  4JZD L;  2WPM E;  4JZE L;  1NFU B;  1DDX A;  1APO A;  4X8U L;  4Z6A L;  1KLI L;  1SZB A;  5CKQ A;  1N1I A;  2J95 B;  2GD4 A;  1G1S A;  4YT7 L;  1XFE A;  4XLW A; 
#chains in the Genus database with same CATH topology
 1HRE A;  4PH9 A;  5E8D A;  2BO2 A;  2YGO A;  2P93 L;  2VWM K;  3HS5 A;  3CFW A;  2Y5G L;  4Y6D B;  1GK5 A;  2EI8 B;  2KL7 A;  4ZHA B;  1HCG B;  1DIY A;  1HT8 A;  2KNI A;  3HO5 A;  1K36 A;  4C16 A;  2UWL B;  1ATB A;  5I46 L;  4MMX B;  1KIG L;  2Y5H L;  3CS7 L;  1F7M A;  2W2N E;  4O1Z A;  4LOR A;  2W26 B;  4D0E A;  2YGP A;  1OB1 C;  4BTU A;  1JBU L;  3POY A;  4BTI A;  1IQM L;  5FDQ A;  1B9W A;  1HAE A;  3MDL A;  1AUT L;  2HOX A;  5JB9 E;  5IKV A;  2VVV L;  2BQ7 A;  2F9B L;  2WPI E;  2WZP P;  2RHP A;  3FCS B;  1A3P A;  2D1J B;  1CEJ A;  3HS6 A;  3RR3 A;  2Y80 B;  2FLB L;  2BZ6 L;  3LC5 B;  3KCG L;  3ZYJ B;  1DX5 I;  4AQT A;  1J9C L;  3N8Z A;  1EZQ B;  3KQC L;  3BPS E;  2J4I B;  2CJI B;  3KL6 B;  2Y5F L;  1FAX L;  3N8W A;  1MQ5 L;  3NT1 A;  4BXS A;  1P9J A;  1EBV A;  3H5C B;  2J2U B;  1EPH A;  3FBY A;  3KRK A;  1EMO A;  1ZAQ A;  3V64 C;  1G1T A;  4M11 A;  1Z6E L;  2TGF A;  1UZJ A;  2W2O E;  1G2L B;  1FF7 A;  1NFW B;  1PFX L;  1X7A L;  2P3F L;  1HJ7 A;  3R05 A;  1IGZ A;  2I9B A;  1IQK L;  1V1I A;  2VH6 B;  1IQI L;  2P3U A;  1EPJ A;  1PRH A;  3S6X A;  1KLO A;  3N8W B;  1NFY B;  2EI7 B;  5L2Z L;  1L5G B;  1IQL L;  2OYU P;  2WFT A;  1JV2 B;  3MQE A;  2MGP A;  1G2M B;  2AYL A;  3ZYI B;  2Q1J B;  4Y79 B;  3LTG D;  1G1R A;  1NFX B;  4Z0K B;  1IQE L;  2P95 L;  4X8V L;  3TK5 B;  1CQE A;  1Q4G A;  6COX A;  1FJS L;  4NGA L;  3GIS X;  1HZ8 A;  1CVW L;  4CSY A;  3TZI A;  1EPG A;  1WHE A;  3HO3 A;  1KLJ L;  1IOE L;  1YO8 A;  2WG4 B;  4ZAE B;  1EQG A;  4RRY A;  1WHF A;  1KSN B;  1ATE A;  2FLR L;  1O5D L;  1HT5 A;  1U67 A;  2MHP A;  3NJP C;  2BOH A;  4CUF A;  1COU A;  1V1H A;  2JJL A;  2W3I B;  4NA9 L;  1DVA L;  4MMZ B;  1EQH A;  1NPE B;  4LMF A;  2WPH E;  4O02 B;  5KIR A;  2VWN L;  3LN1 A;  2WPK E;  5L30 L;  2NPR A;  2P94 L;  2P3T A;  4GU3 A;  4RRX A;  1DQB A;  2VH0 B;  3TK6 B;  4A7I A;  5JVY A;  1F0R B;  3M37 L;  3IIT B;  3C9A C;  5JW1 A;  1TPG A;  3HS7 A;  3CEN L;  2VWO L;  1LK9 A;  1ADX A;  1EAI C;  4RS0 A;  2UWO B;  4Y7B B;  4BDW A;  3U73 A;  5COX A;  2W86 A;  3BT2 A;  2FLG A;  3N8V A;  4CUE A;  3DEM A;  2Y7X B;  2BT7 A;  2W3K B;  1LPZ A;  3TGF A;  5F1A A;  2P16 L;  1TLE A;  1IVO C;  4BTT A;  4X8T L;  3OLU A;  2WG3 C;  2J34 B;  3Q3K B;  3M36 L;  2P3F N;  3PGH A;  1IQN L;  4COX A;  3SOB B;  1JL9 A;  3CA7 A;  1Z6C A;  2OYE P;  1QFK L;  2VWL L;  2P26 A;  4G1M B;  1TOZ A;  5CKN A;  2VRS A;  2RNL A;  4OTY A;  2Y7Z B;  3OLT A;  4A94 C;  2Y38 A;  2DDU A;  4M10 A;  4GU4 A;  1KKE A;  1YUG A;  2VVU L;  1LQD A;  5CIS A;  3LC3 B;  3NTB A;  1F0S B;  3N8Y A;  2J94 B;  5JB8 E;  2M74 A;  2HOR A;  1NT0 A;  3LTF B;  2XC4 L;  3F6U L;  1PXX A;  5IKR A;  2G00 L;  1PGE A;  3KQD L;  1IP0 A;  4XBM A;  2WPL E;  1IQH L;  2XBW L;  1UZP A;  3SOV A;  2BQ6 A;  1EMN A;  3U7U G;  2J38 B;  1CVU A;  4D90 A;  3Q7D A;  2XBX L;  5JBB E;  1MQ6 L;  1P0S L;  1W7X L;  1M1X B;  2MGR A;  3K9X A;  3HPT A;  3LN0 A;  3TH3 L;  5IKT A;  1IQF L;  2KB9 A;  3P5B L;  1ATD A;  2EI6 B;  3N8Y B;  3LAQ A;  2PR3 B;  2BOX A;  1FAK L;  1N7D A;  2BOK L;  2H9E C;  1L3Y A;  1IGX A;  2UWP B;  2XBV L;  3SW2 A;  2PHB B;  2W2Q E;  1UZQ A;  2XC0 L;  2B7D L;  1IJQ A;  2RA0 L;  4D0F A;  3QH0 A;  1CCF A;  1CX2 A;  1IOX A;  3QCW A;  4FM5 A;  1U8C B;  3ASI A;  1LPG A;  1CCV A;  1YUF A;  1W8B L;  1EPI A;  2WYG B;  1FE2 A;  1HRF A;  1WU1 B;  3EGF A;  1XKA L;  1EGF A;  5EGM B;  2K2T A;  1XDT R;  3SOQ A;  1HX2 A;  4JYV L;  4ZXX L;  5L2Y L;  3NTG A;  4RUT A;  4ZH8 B;  2XBY L;  4XL1 A;  1MOX C;  5F19 A;  5K0H B;  1IQJ L;  2BT8 A;  4YZU B;  4ISH L;  2FD6 A;  5JBA E;  3F1S B;  4RRZ A;  4Z0L A;  1F7E A;  2BQW A;  4JZF L;  1C5M F;  1BF9 A;  2WPJ E;  4X8S L;  4TGF A;  1FSB A;  2PUQ L;  4ISI L;  4Y7A B;  2P28 B;  3KK6 A;  4BXW A;  2I9A A;  2W2P E;  1NQL B;  1UZK A;  1V3X B;  2WYJ B;  2BOU A;  2WFX B;  3LIW B;  3V65 B;  5CKM A;  5IKQ A;  2Y82 B;  2YGQ A;  3GCW E;  5KN5 C;  3IJE B;  2KV4 A;  1RFN B;  3BT1 A;  3HO4 A;  1LMJ A;  1NZI A;  1QIU A;  1YUK B;  1URK A;  2W2M E;  2BSF A;  1K37 A;  2H9E L;  1FFM A;  2ADX A;  2FZZ L;  3ENS A;  1HAF A;  3QMO A;  2Y81 B;  1I0U A;  1XKB A;  4NG9 L;  3TBD A;  3KQE L;  2BMG A;  1PTH A;  1ATA A;  1LPK A;  3GCX E;  1G1Q A;  1IQG L;  3ELA L;  3N8X A;  4JYU L;  4Y76 B;  2VJ3 A;  4ZXY L;  2JKH L;  4OTJ A;  3ZYG A;  1YGC L;  2K2S B;  2VVC K;  5JVZ A;  2XC5 L;  4BDX A;  4CUD A;  3KQB L;  1APQ A;  3FFG L;  5JBC E;  4RRW A;  4Y71 B;  4MMY B;  4YT6 L;  4E1G A;  4JZD L;  2WPM E;  4JZE L;  1NFU B;  1DDX A;  1APO A;  4X8U L;  4Z6A L;  1KLI L;  1SZB A;  5CKQ A;  1N1I A;  1LMM A;  2J95 B;  2GD4 A;  1G1S A;  4YT7 L;  1XFE A;  4XLW A; 
#chains in the Genus database with same CATH homology
 1HRE A;  4PH9 A;  5E8D A;  2BO2 A;  2YGO A;  2P93 L;  2VWM K;  3HS5 A;  3CFW A;  2Y5G L;  4Y6D B;  1GK5 A;  2EI8 B;  2KL7 A;  4ZHA B;  1HCG B;  1DIY A;  1HT8 A;  2KNI A;  3HO5 A;  1K36 A;  4C16 A;  2UWL B;  1ATB A;  5I46 L;  4MMX B;  1KIG L;  2Y5H L;  3CS7 L;  1F7M A;  2W2N E;  4O1Z A;  4LOR A;  2W26 B;  4D0E A;  2YGP A;  1OB1 C;  4BTU A;  1JBU L;  3POY A;  4BTI A;  1IQM L;  5FDQ A;  1B9W A;  1HAE A;  3MDL A;  1AUT L;  5JB9 E;  5IKV A;  2VVV L;  2BQ7 A;  2F9B L;  2WPI E;  2WZP P;  2RHP A;  3FCS B;  1A3P A;  2D1J B;  1CEJ A;  3HS6 A;  3RR3 A;  2Y80 B;  2FLB L;  2BZ6 L;  3LC5 B;  3KCG L;  3ZYJ B;  1DX5 I;  4AQT A;  1J9C L;  3N8Z A;  1EZQ B;  3KQC L;  2J4I B;  3BPS E;  2CJI B;  3KL6 B;  2Y5F L;  1FAX L;  3N8W A;  1MQ5 L;  3NT1 A;  4BXS A;  1P9J A;  1EBV A;  3H5C B;  2J2U B;  1EPH A;  3FBY A;  3KRK A;  1EMO A;  1ZAQ A;  3V64 C;  1G1T A;  4M11 A;  1Z6E L;  2TGF A;  1UZJ A;  2W2O E;  1G2L B;  1FF7 A;  1NFW B;  1PFX L;  1X7A L;  2P3F L;  1HJ7 A;  3R05 A;  1IGZ A;  2I9B A;  1IQK L;  2VH6 B;  1IQI L;  2P3U A;  1EPJ A;  1PRH A;  3S6X A;  1KLO A;  3N8W B;  1NFY B;  2EI7 B;  5L2Z L;  1L5G B;  1IQL L;  2OYU P;  2WFT A;  1JV2 B;  3MQE A;  2MGP A;  1G2M B;  2AYL A;  3ZYI B;  2Q1J B;  4Y79 B;  3LTG D;  1G1R A;  1NFX B;  4Z0K B;  1IQE L;  2P95 L;  4X8V L;  3TK5 B;  1CQE A;  1Q4G A;  6COX A;  1FJS L;  4NGA L;  3GIS X;  1HZ8 A;  1CVW L;  4CSY A;  3TZI A;  1EPG A;  1WHE A;  3HO3 A;  1KLJ L;  1IOE L;  1YO8 A;  2WG4 B;  4ZAE B;  1EQG A;  4RRY A;  1WHF A;  1KSN B;  1ATE A;  2FLR L;  1O5D L;  1HT5 A;  1U67 A;  2MHP A;  3NJP C;  2BOH A;  4CUF A;  1COU A;  2W3I B;  4NA9 L;  1DVA L;  4MMZ B;  1EQH A;  1NPE B;  4LMF A;  2WPH E;  4O02 B;  5KIR A;  2VWN L;  3LN1 A;  2WPK E;  5L30 L;  2NPR A;  2P94 L;  2P3T A;  4RRX A;  1DQB A;  2VH0 B;  3TK6 B;  4A7I A;  5JVY A;  1F0R B;  3M37 L;  3IIT B;  3C9A C;  5JW1 A;  1TPG A;  3HS7 A;  3CEN L;  2VWO L;  1ADX A;  1EAI C;  4RS0 A;  2UWO B;  4Y7B B;  4BDW A;  3U73 A;  5COX A;  2W86 A;  3BT2 A;  2FLG A;  3N8V A;  4CUE A;  3DEM A;  2Y7X B;  2W3K B;  1LPZ A;  3TGF A;  5F1A A;  2P16 L;  1TLE A;  1IVO C;  4BTT A;  4X8T L;  3OLU A;  2WG3 C;  2J34 B;  3Q3K B;  3M36 L;  2P3F N;  3PGH A;  1IQN L;  4COX A;  3SOB B;  1JL9 A;  3CA7 A;  1Z6C A;  2OYE P;  1QFK L;  2VWL L;  2P26 A;  4G1M B;  1TOZ A;  5CKN A;  2RNL A;  4OTY A;  2Y7Z B;  3OLT A;  4A94 C;  2Y38 A;  2DDU A;  4M10 A;  2VVU L;  1YUG A;  1LQD A;  5CIS A;  3LC3 B;  3NTB A;  1F0S B;  3N8Y A;  2J94 B;  5JB8 E;  2M74 A;  1NT0 A;  3LTF B;  2XC4 L;  3F6U L;  1PXX A;  5IKR A;  2G00 L;  1PGE A;  3KQD L;  1IP0 A;  4XBM A;  2WPL E;  1IQH L;  2XBW L;  1UZP A;  3SOV A;  2BQ6 A;  1EMN A;  3U7U G;  2J38 B;  1CVU A;  4D90 A;  3Q7D A;  2XBX L;  5JBB E;  1MQ6 L;  1P0S L;  1W7X L;  1M1X B;  2MGR A;  3K9X A;  3HPT A;  3LN0 A;  3TH3 L;  5IKT A;  1IQF L;  2KB9 A;  3P5B L;  1ATD A;  2EI6 B;  3N8Y B;  3LAQ A;  2PR3 B;  2BOX A;  1FAK L;  1N7D A;  2BOK L;  2H9E C;  1L3Y A;  1IGX A;  2UWP B;  2XBV L;  3SW2 A;  2PHB B;  2W2Q E;  1UZQ A;  2XC0 L;  2B7D L;  1IJQ A;  2RA0 L;  4D0F A;  3QH0 A;  1CCF A;  1CX2 A;  1IOX A;  3QCW A;  4FM5 A;  1U8C B;  3ASI A;  1LPG A;  1CCV A;  1YUF A;  1W8B L;  1EPI A;  2WYG B;  1FE2 A;  1HRF A;  1WU1 B;  3EGF A;  1XKA L;  1EGF A;  5EGM B;  2K2T A;  1XDT R;  3SOQ A;  1HX2 A;  4JYV L;  4ZXX L;  5L2Y L;  3NTG A;  4RUT A;  4ZH8 B;  2XBY L;  4XL1 A;  1MOX C;  5F19 A;  5K0H B;  1IQJ L;  4YZU B;  4ISH L;  2FD6 A;  5JBA E;  3F1S B;  4RRZ A;  4Z0L A;  1F7E A;  2BQW A;  4JZF L;  1C5M F;  1BF9 A;  2WPJ E;  4X8S L;  4TGF A;  1FSB A;  2PUQ L;  4ISI L;  4Y7A B;  2P28 B;  3KK6 A;  4BXW A;  2I9A A;  2W2P E;  1NQL B;  1UZK A;  1V3X B;  2WYJ B;  2BOU A;  2WFX B;  3LIW B;  3V65 B;  5CKM A;  5IKQ A;  2Y82 B;  2YGQ A;  3GCW E;  5KN5 C;  3IJE B;  2KV4 A;  1RFN B;  3BT1 A;  3HO4 A;  1LMJ A;  1NZI A;  1YUK B;  1URK A;  2W2M E;  1K37 A;  2H9E L;  1FFM A;  2ADX A;  2FZZ L;  3ENS A;  1HAF A;  3QMO A;  2Y81 B;  1I0U A;  1XKB A;  4NG9 L;  3TBD A;  3KQE L;  2BMG A;  1PTH A;  1ATA A;  1LPK A;  3GCX E;  1G1Q A;  1IQG L;  3ELA L;  3N8X A;  4JYU L;  4Y76 B;  2VJ3 A;  4ZXY L;  2JKH L;  4OTJ A;  3ZYG A;  1YGC L;  2K2S B;  2VVC K;  5JVZ A;  2XC5 L;  4BDX A;  4CUD A;  3KQB L;  1APQ A;  3FFG L;  5JBC E;  4RRW A;  4Y71 B;  4MMY B;  4YT6 L;  4E1G A;  4JZD L;  2WPM E;  4JZE L;  1NFU B;  1DDX A;  1APO A;  4X8U L;  4Z6A L;  1KLI L;  1SZB A;  5CKQ A;  1N1I A;  1LMM A;  2J95 B;  2GD4 A;  1G1S A;  4YT7 L;  1XFE A;  4XLW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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