3TH3L

Mg2+ is required for optimal folding of the gamma-carboxyglutamic acid (gla) domains of vitamin k-dependent clotting factors at physiological ca2+
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
96
structure length
96
Chain Sequence
GDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla) Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+
rcsb
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Coagulation factor VII light chain
total genus 17
structure length 96
sequence length 96
ec nomenclature ec 3.4.21.21: Coagulation factor VIIa.
pdb deposition date 2011-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF00008 EGF EGF-like domain
L PF00594 Gla Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3th3L02
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3th3L01
3KK6A 1NZIA 3POYA 2BZ6L 4OTJA 1IQFL 1COUA 1TOZA 4O1ZA 2FD6A 1CCFA 5JW1A 2Y7ZB 1HAEA 1EPHA 3N8VA 2FLGA 3KL6B 3HO5A 1N1IA 2CJIB 2VWOL 2BOHA 3LC3B 2XBVL 3TZIA 1G2LB 4LMFA 1IQML 6COXA 4M10A 1L3YA 2DDUA 1RFNB 5L2ZL 4Y71B 4X8VL 4OTYA 3RR3A 2J4IB 1IQKL 1YGCL 2J38B 2MGRA 2WPHE 2W2OE 2BQWA 3SOQA 1DIYA 1MOXC 2Y38A 2WPIE 2FLRL 2WYJB 1UZQA 2EI6B 1J9CL 2PR3B 2W3KB 1UZKA 3KRKA 4ZH8B 1HREA 4G1MB 1APQA 3SOVA 3LN1A 3QCWA 2TGFA 1CCVA 2W2PE 4BTIA 4XLWA 4E1GA 1IQGL 1FFMA 2W26B 1JBUL 2AYLA 2WG4B 3ENSA 2WFXB 5KIRA 3KQBL 4JYVL 3CS7L 1ADXA 4ISIL 3V64C 1TLEA 1HZ8A 1B9WA 3HS5A 1EPGA 3FFGL 4BXSA 4JYUL 1HRFA 3GCWE 2WFTA 2RNLA 1LPGA 5IKRA 2BQ6A 1FF7A 1PFXL 4JZFL 5FDQA 1IQNL 4CSYA 2PHBB 4BTTA 2ADXA 4BDXA 3N8YB 2EI8B 2P3UA 2BQ7A 3MQEA 2Y5HL 1LMJA 5IKTA 1LPKA 2Y81B 2XBXL 1OB1C 3R05A 1G1SA 1APOA 5IKVA 1IQIL 1EAIC 5JBBE 3TH3L 1PTHA 2WPLE 3LC5B 1YUGA 4Y76B 4M11A 2VVVL 3CFWA 1JV2B 5CISA 2WPME 4ZXXL 2Y5GL 1F7EA 1EPIA 4D90A 4Z6AL 1DDXA 4ZXYL 1HT8A 1G1QA 1IVOC 3OLUA 5L2YL 2P95L 4RS0A 5CKNA 3EGFA 4ISHL 3M37L 3KQEL 1G1RA 1HAFA 4ZHAB 3NJPC 1KIGL 1YO8A 4COXA 2WG3C 2BOKL 1XKBA 4AQTA 2J34B 2VH6B 5CKQA 4CUDA 1KSNB 1F0RB 2P3FL 1Z6CA 4RUTA 1I0UA 4NA9L 1DX5I 3SW2A 1CVUA 3F6UL 3GISX 2RHPA 3NTBA 1W7XL 3FCSB 1WU1B 2XBYL 1IQEL 4ZAEB 2YGPA 1DVAL 4PH9A 2KV4A 5L30L 3NT1A 3NTGA 1LQDA 2M74A 5KN5C 2Y7XB 1DQBA 1NFYB 1O5DL 4YZUB 2PUQL 3TBDA 1FSBA 4XL1A 3Q7DA 1ATDA 4YT6L 5E8DA 4RRYA 4NG9L 1EMNA 1YUFA 4X8SL 1KLJL 4BXWA 3U7UG 3IJEB 4FM5A 3TK6B 2W2NE 4JZDL 1AUTL 1XKAL 3N8ZA 4RRXA 5F19A 1FJSL 2P28B 5JB8E 1CQEA 2W3IB 1QFKL 2P3TA 1HJ7A 4Y79B 2VJ3A 1PRHA 4C16A 5JVYA 2WYGB 1IP0A 2BO2A 2Y80B 1HT5A 3HS7A 3IITB 2Y5FL 3HO4A 2JKHL 1SZBA 1U67A 1NFWB 3HS6A 1NFXB 1UZPA 1EBVA 3N8XA 3C9AC 1X7AL 3ZYJB 2BOXA 3ZYIB 2W2ME 4Z0LA 1UZJA 3PGHA 5JBAE 2G00L 2J94B 1N7DA 1XDTR 4BTUA 3CA7A 1NFUB 1P0SL 2BMGA 2P26A 1PGEA 1IOEL 1Q4GA 1K36A 1P9JA 2WPKE 3BT2A 1M1XB 2VVUL 1URKA 1XFEA 1IQJL 4Y6DB 2D1JB 3HPTA 1CVWL 3OLTA 2P94L 3M36L 5JVZA 4MMZB 1HX2A 1V3XB 1W8BL 3N8YA 5IKQA 4Z0KB 4YT7L 1KLOA 3BT1A 4MMXB 4Y7AB 2VH0B 3KQDL 1IGXA 1IQLL 3BPSE 3DEMA 1NT0A 1EQHA 1NPEB 1MQ5L 2KL7A 1ATEA 2I9BA 3HO3A 4O02B 4XBMA 2RA0L 1EMOA 2B7DL 4A7IA 3QMOA 3SOBB 2VWNL 1GK5A 2NPRA 1WHFA 2BOUA 4MMYB 3MDLA 1MQ6L 4Y7BB 2EI7B 1IOXA 2VWMK 3LTGD 1TPGA 1KLIL 1F0SB 2GD4A 4TGFA 4D0FA 4X8UL 2YGOA 5JB9E 3TGFA 2F9BL 1C5MF 1ATBA 1WHEA 4RRWA 5K0HB 3LN0A 2UWLB 3F1SB 4JZEL 3QH0A 3LIWB 1ATAA 2KB9A 1IQHL 1K37A 2FLBL 2VWLL 4CUEA 2W2QE 2Y82B 3GCXE 1IJQA 1EPJA 3ELAL 1YUKB 2XC0L 2OYUP 5JBCE 1F7MA 1PXXA 4RRZA 2FZZL 3N8WB 3U73A 2MGPA 2H9EL 1EZQB 2P16L 2P3FN 3ZYGA 1JL9A 3LAQA 4NGAL 1ZAQA 2K2TA 3P5BL 2XC5L 2J95B 2Q1JB 5F1AA 1IGZA 2UWPB 1G2MB 2J2UB 2MHPA 2P93L 1A3PA 3H5CB 1BF9A 3FBYA 2XBWL 1FE2A 1LPZA 1HCGB 5CKMA 1CEJA 5EGMB 3CENL 1Z6EL 2VVCK 3KCGL 1EQGA 2K2SB 2UWOB 4LORA 4BDWA 1EGFA 1G1TA 1NQLB 3K9XA 5COXA 5I46L 3LTFB 1FAKL 1L5GB 3ASIA 3Q3KB 4D0EA 2OYEP 3KQCL 1CX2A 2XC4L 3TK5B 3V65B 3N8WA 1FAXL 2W86A 4X8TL 2WPJE 4CUFA 1U8CB 2I9AA
chains in the Genus database with same CATH superfamily
3KK6A 2YGQA 1NZIA 3POYA 2BZ6L 4OTJA 1IQFL 1COUA 1TOZA 4O1ZA 2FD6A 1CCFA 5JW1A 2Y7ZB 1HAEA 1EPHA 3N8VA 2FLGA 3KL6B 3HO5A 1N1IA 2CJIB 2HORA 2VWOL 2BOHA 3LC3B 2XBVL 3TZIA 1G2LB 4LMFA 1IQML 6COXA 4M10A 1L3YA 2DDUA 1RFNB 5L2ZL 4Y71B 4X8VL 4OTYA 3RR3A 2J4IB 1IQKL 1YGCL 2J38B 2MGRA 2WPHE 2W2OE 2BQWA 3SOQA 1DIYA 1MOXC 2Y38A 2WPIE 2FLRL 2WYJB 1UZQA 2EI6B 1J9CL 2PR3B 2W3KB 1UZKA 3KRKA 4ZH8B 1HREA 2H9EC 4G1MB 1APQA 3SOVA 3LN1A 3QCWA 2TGFA 1CCVA 2W2PE 4BTIA 4XLWA 4E1GA 1IQGL 1FFMA 2W26B 1JBUL 2AYLA 2WG4B 3ENSA 2WFXB 5KIRA 3KQBL 4JYVL 3CS7L 1V1HA 1ADXA 4ISIL 3V64C 2HOXA 1TLEA 1HZ8A 1B9WA 3HS5A 1EPGA 3FFGL 4BXSA 4JYUL 1HRFA 3GCWE 2WFTA 2RNLA 1LPGA 5IKRA 2BQ6A 1FF7A 1PFXL 4JZFL 5FDQA 1IQNL 4CSYA 2PHBB 4BTTA 2ADXA 4BDXA 2EI8B 2P3UA 3N8YB 2BQ7A 3MQEA 2Y5HL 1LMJA 5IKTA 1LPKA 2Y81B 4A94C 2XBXL 1OB1C 3R05A 1G1SA 1APOA 5IKVA 1IQIL 1EAIC 5JBBE 3TH3L 1PTHA 2WPLE 3LC5B 1YUGA 4Y76B 4M11A 2VVVL 3CFWA 1JV2B 5CISA 2WPME 4ZXXL 2Y5GL 1F7EA 1EPIA 4D90A 4Z6AL 1DDXA 4ZXYL 1HT8A 1G1QA 1IVOC 3OLUA 5L2YL 2P95L 4RS0A 5CKNA 3EGFA 4ISHL 3M37L 3KQEL 1G1RA 1HAFA 4ZHAB 3NJPC 3S6XA 1KIGL 1YO8A 4COXA 2WG3C 2BOKL 1LMMA 1XKBA 4AQTA 2J34B 2VH6B 5CKQA 4CUDA 1KSNB 1F0RB 2P3FL 1Z6CA 4RUTA 1I0UA 4NA9L 1DX5I 3SW2A 1CVUA 3F6UL 3GISX 2RHPA 2VRSA 3NTBA 1W7XL 3FCSB 1WU1B 2XBYL 2JJLA 1IQEL 4ZAEB 2YGPA 2BSFA 1DVAL 4PH9A 2KV4A 5L30L 3NT1A 3NTGA 1LQDA 2M74A 5KN5C 2Y7XB 1DQBA 1NFYB 1O5DL 4YZUB 2PUQL 3TBDA 1FSBA 4XL1A 3Q7DA 1ATDA 4YT6L 5E8DA 4RRYA 4NG9L 1EMNA 1YUFA 4X8SL 1KLJL 4BXWA 3U7UG 3IJEB 4FM5A 3TK6B 2W2NE 4JZDL 1AUTL 1XKAL 3N8ZA 4RRXA 5F19A 1FJSL 2P28B 5JB8E 1CQEA 2W3IB 1QFKL 2P3TA 1HJ7A 4Y79B 2VJ3A 1PRHA 4C16A 5JVYA 2WYGB 1IP0A 2BO2A 2Y80B 1HT5A 3HS7A 3IITB 2Y5FL 3HO4A 2JKHL 1SZBA 1U67A 1NFWB 3HS6A 1NFXB 1UZPA 1EBVA 3N8XA 3C9AC 1X7AL 3ZYJB 4GU3A 2BOXA 3ZYIB 2W2ME 4Z0LA 1UZJA 3PGHA 5JBAE 2G00L 2J94B 1N7DA 1XDTR 4BTUA 3CA7A 1NFUB 1P0SL 2BMGA 2P26A 1PGEA 1IOEL 1Q4GA 1K36A 1P9JA 2WPKE 3BT2A 1M1XB 2VVUL 1URKA 1XFEA 1IQJL 4Y6DB 2D1JB 3HPTA 1CVWL 3OLTA 2P94L 3M36L 5JVZA 4MMZB 1HX2A 1V3XB 1W8BL 3N8YA 5IKQA 4Z0KB 4YT7L 1KLOA 3BT1A 4GU4A 4MMXB 4Y7AB 2VH0B 3KQDL 1IGXA 1IQLL 3BPSE 3DEMA 1NT0A 1EQHA 1NPEB 1MQ5L 2KL7A 1ATEA 2I9BA 3HO3A 4O02B 4XBMA 2RA0L 1EMOA 2B7DL 1QIUA 4A7IA 3QMOA 3SOBB 2VWNL 1GK5A 2NPRA 1WHFA 2BOUA 4MMYB 3MDLA 1MQ6L 4Y7BB 2EI7B 1IOXA 2VWMK 2BT8A 3LTGD 1TPGA 1KLIL 1F0SB 2GD4A 4TGFA 4D0FA 4X8UL 2YGOA 5JB9E 3TGFA 2F9BL 1C5MF 1ATBA 1WHEA 4RRWA 5K0HB 3LN0A 2UWLB 3F1SB 4JZEL 3QH0A 3LIWB 1ATAA 2KB9A 1IQHL 1K37A 2FLBL 2VWLL 4CUEA 2W2QE 2Y82B 2KNIA 3GCXE 1IJQA 1EPJA 3ELAL 1YUKB 2XC0L 2OYUP 5JBCE 1F7MA 1PXXA 4RRZA 2FZZL 3N8WB 1LK9A 3U73A 2MGPA 2H9EL 1EZQB 2P16L 2P3FN 3ZYGA 1V1IA 1JL9A 3LAQA 4NGAL 1ZAQA 2K2TA 3P5BL 2XC5L 2J95B 2Q1JB 5F1AA 1IGZA 2UWPB 1G2MB 2J2UB 2MHPA 2P93L 1A3PA 2BT7A 3H5CB 1BF9A 3FBYA 2XBWL 1FE2A 1LPZA 1HCGB 5CKMA 1CEJA 2WZPP 5EGMB 3CENL 1Z6EL 2VVCK 3KCGL 1EQGA 2K2SB 2UWOB 4LORA 4BDWA 1EGFA 1G1TA 1NQLB 3K9XA 5COXA 5I46L 3LTFB 1FAKL 1L5GB 3ASIA 3Q3KB 4D0EA 2OYEP 3KQCL 1CX2A 2XC4L 3TK5B 1KKEA 3V65B 3N8WA 1FAXL 2W86A 4X8TL 2WPJE 4CUFA 1U8CB 2I9AA
chains in the Genus database with same CATH topology
3KK6A 2YGQA 1NZIA 3POYA 2BZ6L 4OTJA 1IQFL 1COUA 1TOZA 4O1ZA 2FD6A 1CCFA 5JW1A 2Y7ZB 1HAEA 1EPHA 3N8VA 2FLGA 3KL6B 3HO5A 1N1IA 2CJIB 2VWOL 2BOHA 3LC3B 2XBVL 3TZIA 1G2LB 4LMFA 1IQML 6COXA 4M10A 1L3YA 2DDUA 1RFNB 5L2ZL 4Y71B 4X8VL 4OTYA 3RR3A 2J4IB 1IQKL 1YGCL 2J38B 2MGRA 2WPHE 2W2OE 2BQWA 3SOQA 1DIYA 1MOXC 2Y38A 2WPIE 2FLRL 2WYJB 1UZQA 2EI6B 1J9CL 2PR3B 2W3KB 1UZKA 3KRKA 4ZH8B 1HREA 2H9EC 4G1MB 1APQA 3SOVA 3LN1A 3QCWA 2TGFA 1CCVA 2W2PE 4BTIA 4XLWA 4E1GA 1IQGL 1FFMA 2W26B 1JBUL 2AYLA 2WG4B 3ENSA 2WFXB 5KIRA 3KQBL 4JYVL 3CS7L 1ADXA 4ISIL 3V64C 1TLEA 1HZ8A 1B9WA 3HS5A 1EPGA 3FFGL 4BXSA 4JYUL 1HRFA 3GCWE 2WFTA 2RNLA 1LPGA 5IKRA 2BQ6A 1FF7A 1PFXL 4JZFL 5FDQA 1IQNL 4CSYA 2PHBB 4BTTA 2ADXA 4BDXA 2EI8B 2P3UA 3N8YB 2BQ7A 3MQEA 2Y5HL 1LMJA 5IKTA 1LPKA 2Y81B 4A94C 2XBXL 1OB1C 3R05A 1G1SA 1APOA 5IKVA 1IQIL 1EAIC 5JBBE 3TH3L 1PTHA 2WPLE 3LC5B 1YUGA 4Y76B 4M11A 2VVVL 3CFWA 1JV2B 5CISA 2WPME 4ZXXL 2Y5GL 1F7EA 1EPIA 4D90A 4Z6AL 1DDXA 4ZXYL 1HT8A 1G1QA 1IVOC 3OLUA 5L2YL 2P95L 4RS0A 5CKNA 3EGFA 4ISHL 3M37L 3KQEL 1G1RA 1HAFA 4ZHAB 3NJPC 3S6XA 1KIGL 1YO8A 4COXA 2WG3C 2BOKL 1LMMA 1XKBA 4AQTA 2J34B 2VH6B 5CKQA 4CUDA 1KSNB 1F0RB 2P3FL 1Z6CA 4RUTA 1I0UA 4NA9L 1DX5I 3SW2A 1CVUA 3F6UL 3GISX 2RHPA 3NTBA 1W7XL 3FCSB 1WU1B 2XBYL 1IQEL 4ZAEB 2YGPA 1DVAL 4PH9A 2KV4A 5L30L 3NT1A 3NTGA 1LQDA 2M74A 5KN5C 2Y7XB 1DQBA 1NFYB 1O5DL 4YZUB 2PUQL 3TBDA 1FSBA 4XL1A 3Q7DA 1ATDA 4YT6L 5E8DA 4RRYA 4NG9L 1EMNA 1YUFA 4X8SL 1KLJL 4BXWA 3U7UG 3IJEB 4FM5A 3TK6B 2W2NE 4JZDL 1AUTL 1XKAL 3N8ZA 4RRXA 5F19A 1FJSL 2P28B 5JB8E 1CQEA 2W3IB 1QFKL 2P3TA 1HJ7A 4Y79B 2VJ3A 1PRHA 4C16A 5JVYA 2WYGB 1IP0A 2BO2A 2Y80B 1HT5A 3HS7A 3IITB 2Y5FL 3HO4A 2JKHL 1SZBA 1U67A 1NFWB 3HS6A 1NFXB 1UZPA 1EBVA 3N8XA 3C9AC 1X7AL 3ZYJB 2BOXA 3ZYIB 2W2ME 4Z0LA 1UZJA 3PGHA 5JBAE 2G00L 2J94B 1N7DA 1XDTR 4BTUA 3CA7A 1NFUB 1P0SL 2BMGA 2P26A 1PGEA 1IOEL 1Q4GA 1K36A 1P9JA 2WPKE 3BT2A 1M1XB 2VVUL 1URKA 1XFEA 1IQJL 4Y6DB 2D1JB 3HPTA 1CVWL 3OLTA 2P94L 3M36L 5JVZA 4MMZB 1HX2A 1V3XB 1W8BL 3N8YA 5IKQA 4Z0KB 4YT7L 1KLOA 3BT1A 4MMXB 4Y7AB 2VH0B 3KQDL 1IGXA 1IQLL 3BPSE 3DEMA 1NT0A 1EQHA 1NPEB 1MQ5L 2KL7A 1ATEA 2I9BA 3HO3A 4O02B 4XBMA 2RA0L 1EMOA 2B7DL 4A7IA 3QMOA 3SOBB 2VWNL 1GK5A 2NPRA 1WHFA 2BOUA 4MMYB 3MDLA 1MQ6L 4Y7BB 2EI7B 1IOXA 2VWMK 3LTGD 1TPGA 1KLIL 1F0SB 2GD4A 4TGFA 4D0FA 4X8UL 2YGOA 5JB9E 3TGFA 2F9BL 1C5MF 1ATBA 1WHEA 4RRWA 5K0HB 3LN0A 2UWLB 3F1SB 4JZEL 3QH0A 3LIWB 1ATAA 2KB9A 1IQHL 1K37A 2FLBL 2VWLL 4CUEA 2W2QE 2Y82B 2KNIA 3GCXE 1IJQA 1EPJA 3ELAL 1YUKB 2XC0L 2OYUP 5JBCE 1F7MA 1PXXA 4RRZA 2FZZL 3N8WB 3U73A 2MGPA 2H9EL 1EZQB 2P16L 2P3FN 3ZYGA 1JL9A 3LAQA 4NGAL 1ZAQA 2K2TA 3P5BL 2XC5L 2J95B 2Q1JB 5F1AA 1IGZA 2UWPB 1G2MB 2J2UB 2MHPA 2P93L 1A3PA 3H5CB 1BF9A 3FBYA 2XBWL 1FE2A 1LPZA 1HCGB 5CKMA 1CEJA 2WZPP 5EGMB 3CENL 1Z6EL 2VVCK 3KCGL 1EQGA 2K2SB 2UWOB 4LORA 4BDWA 1EGFA 1G1TA 1NQLB 3K9XA 5COXA 5I46L 3LTFB 1FAKL 1L5GB 3ASIA 3Q3KB 4D0EA 2OYEP 3KQCL 1CX2A 2XC4L 3TK5B 3V65B 3N8WA 1FAXL 2W86A 4X8TL 2WPJE 4CUFA 1U8CB 2I9AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KK6 A;  1NZI A;  3POY A;  2BZ6 L;  4OTJ A;  1IQF L;  1COU A;  1TOZ A;  4O1Z A;  2FD6 A;  1CCF A;  5JW1 A;  2Y7Z B;  1HAE A;  1EPH A;  3N8V A;  2FLG A;  3KL6 B;  3HO5 A;  1N1I A;  2CJI B;  2VWO L;  2BOH A;  3LC3 B;  2XBV L;  3TZI A;  1G2L B;  4LMF A;  1IQM L;  6COX A;  4M10 A;  1L3Y A;  2DDU A;  1RFN B;  5L2Z L;  4Y71 B;  4X8V L;  4OTY A;  3RR3 A;  2J4I B;  1IQK L;  1YGC L;  2J38 B;  2MGR A;  2WPH E;  2W2O E;  2BQW A;  3SOQ A;  1DIY A;  1MOX C;  2Y38 A;  2WPI E;  2FLR L;  2WYJ B;  1UZQ A;  2EI6 B;  1J9C L;  2PR3 B;  2W3K B;  1UZK A;  3KRK A;  4ZH8 B;  1HRE A;  4G1M B;  1APQ A;  3SOV A;  3LN1 A;  3QCW A;  2TGF A;  1CCV A;  2W2P E;  4BTI A;  4XLW A;  4E1G A;  1IQG L;  1FFM A;  2W26 B;  1JBU L;  2AYL A;  2WG4 B;  3ENS A;  2WFX B;  5KIR A;  3KQB L;  4JYV L;  3CS7 L;  1ADX A;  4ISI L;  3V64 C;  1TLE A;  1HZ8 A;  1B9W A;  3HS5 A;  1EPG A;  3FFG L;  4BXS A;  4JYU L;  1HRF A;  3GCW E;  2WFT A;  2RNL A;  1LPG A;  5IKR A;  2BQ6 A;  1FF7 A;  1PFX L;  4JZF L;  5FDQ A;  1IQN L;  4CSY A;  2PHB B;  4BTT A;  2ADX A;  4BDX A;  3N8Y B;  2EI8 B;  2P3U A;  2BQ7 A;  3MQE A;  2Y5H L;  1LMJ A;  5IKT A;  1LPK A;  2Y81 B;  2XBX L;  1OB1 C;  3R05 A;  1G1S A;  1APO A;  5IKV A;  1IQI L;  1EAI C;  5JBB E;  3TH3 L;  1PTH A;  2WPL E;  3LC5 B;  1YUG A;  4Y76 B;  4M11 A;  2VVV L;  3CFW A;  1JV2 B;  5CIS A;  2WPM E;  4ZXX L;  2Y5G L;  1F7E A;  1EPI A;  4D90 A;  4Z6A L;  1DDX A;  4ZXY L;  1HT8 A;  1G1Q A;  1IVO C;  3OLU A;  5L2Y L;  2P95 L;  4RS0 A;  5CKN A;  3EGF A;  4ISH L;  3M37 L;  3KQE L;  1G1R A;  1HAF A;  4ZHA B;  3NJP C;  1KIG L;  1YO8 A;  4COX A;  2WG3 C;  2BOK L;  1XKB A;  4AQT A;  2J34 B;  2VH6 B;  5CKQ A;  4CUD A;  1KSN B;  1F0R B;  2P3F L;  1Z6C A;  4RUT A;  1I0U A;  4NA9 L;  1DX5 I;  3SW2 A;  1CVU A;  3F6U L;  3GIS X;  2RHP A;  3NTB A;  1W7X L;  3FCS B;  1WU1 B;  2XBY L;  1IQE L;  4ZAE B;  2YGP A;  1DVA L;  4PH9 A;  2KV4 A;  5L30 L;  3NT1 A;  3NTG A;  1LQD A;  2M74 A;  5KN5 C;  2Y7X B;  1DQB A;  1NFY B;  1O5D L;  4YZU B;  2PUQ L;  3TBD A;  1FSB A;  4XL1 A;  3Q7D A;  1ATD A;  4YT6 L;  5E8D A;  4RRY A;  4NG9 L;  1EMN A;  1YUF A;  4X8S L;  1KLJ L;  4BXW A;  3U7U G;  3IJE B;  4FM5 A;  3TK6 B;  2W2N E;  4JZD L;  1AUT L;  1XKA L;  3N8Z A;  4RRX A;  5F19 A;  1FJS L;  2P28 B;  5JB8 E;  1CQE A;  2W3I B;  1QFK L;  2P3T A;  1HJ7 A;  4Y79 B;  2VJ3 A;  1PRH A;  4C16 A;  5JVY A;  2WYG B;  1IP0 A;  2BO2 A;  2Y80 B;  1HT5 A;  3HS7 A;  3IIT B;  2Y5F L;  3HO4 A;  2JKH L;  1SZB A;  1U67 A;  1NFW B;  3HS6 A;  1NFX B;  1UZP A;  1EBV A;  3N8X A;  3C9A C;  1X7A L;  3ZYJ B;  2BOX A;  3ZYI B;  2W2M E;  4Z0L A;  1UZJ A;  3PGH A;  5JBA E;  2G00 L;  2J94 B;  1N7D A;  1XDT R;  4BTU A;  3CA7 A;  1NFU B;  1P0S L;  2BMG A;  2P26 A;  1PGE A;  1IOE L;  1Q4G A;  1K36 A;  1P9J A;  2WPK E;  3BT2 A;  1M1X B;  2VVU L;  1URK A;  1XFE A;  1IQJ L;  4Y6D B;  2D1J B;  3HPT A;  1CVW L;  3OLT A;  2P94 L;  3M36 L;  5JVZ A;  4MMZ B;  1HX2 A;  1V3X B;  1W8B L;  3N8Y A;  5IKQ A;  4Z0K B;  4YT7 L;  1KLO A;  3BT1 A;  4MMX B;  4Y7A B;  2VH0 B;  3KQD L;  1IGX A;  1IQL L;  3BPS E;  3DEM A;  1NT0 A;  1EQH A;  1NPE B;  1MQ5 L;  2KL7 A;  1ATE A;  2I9B A;  3HO3 A;  4O02 B;  4XBM A;  2RA0 L;  1EMO A;  2B7D L;  4A7I A;  3QMO A;  3SOB B;  2VWN L;  1GK5 A;  2NPR A;  1WHF A;  2BOU A;  4MMY B;  3MDL A;  1MQ6 L;  4Y7B B;  2EI7 B;  1IOX A;  2VWM K;  3LTG D;  1TPG A;  1KLI L;  1F0S B;  2GD4 A;  4TGF A;  4D0F A;  4X8U L;  2YGO A;  5JB9 E;  3TGF A;  2F9B L;  1C5M F;  1ATB A;  1WHE A;  4RRW A;  5K0H B;  3LN0 A;  2UWL B;  3F1S B;  4JZE L;  3QH0 A;  3LIW B;  1ATA A;  2KB9 A;  1IQH L;  1K37 A;  2FLB L;  2VWL L;  4CUE A;  2W2Q E;  2Y82 B;  3GCX E;  1IJQ A;  1EPJ A;  3ELA L;  1YUK B;  2XC0 L;  2OYU P;  5JBC E;  1F7M A;  1PXX A;  4RRZ A;  2FZZ L;  3N8W B;  3U73 A;  2MGP A;  2H9E L;  1EZQ B;  2P16 L;  2P3F N;  3ZYG A;  1JL9 A;  3LAQ A;  4NGA L;  1ZAQ A;  2K2T A;  3P5B L;  2XC5 L;  2J95 B;  2Q1J B;  5F1A A;  1IGZ A;  2UWP B;  1G2M B;  2J2U B;  2MHP A;  2P93 L;  1A3P A;  3H5C B;  1BF9 A;  3FBY A;  2XBW L;  1FE2 A;  1LPZ A;  1HCG B;  5CKM A;  1CEJ A;  5EGM B;  3CEN L;  1Z6E L;  2VVC K;  3KCG L;  1EQG A;  2K2S B;  2UWO B;  4LOR A;  4BDW A;  1EGF A;  1G1T A;  1NQL B;  3K9X A;  5COX A;  5I46 L;  3LTF B;  1FAK L;  1L5G B;  3ASI A;  3Q3K B;  4D0E A;  2OYE P;  3KQC L;  1CX2 A;  2XC4 L;  3TK5 B;  3V65 B;  3N8W A;  1FAX L;  2W86 A;  4X8T L;  2WPJ E;  4CUF A;  1U8C B;  2I9A A; 
#chains in the Genus database with same CATH topology
 3KK6 A;  2YGQ A;  1NZI A;  3POY A;  2BZ6 L;  4OTJ A;  1IQF L;  1COU A;  1TOZ A;  4O1Z A;  2FD6 A;  1CCF A;  5JW1 A;  2Y7Z B;  1HAE A;  1EPH A;  3N8V A;  2FLG A;  3KL6 B;  3HO5 A;  1N1I A;  2CJI B;  2HOR A;  2VWO L;  2BOH A;  3LC3 B;  2XBV L;  3TZI A;  1G2L B;  4LMF A;  1IQM L;  6COX A;  4M10 A;  1L3Y A;  2DDU A;  1RFN B;  5L2Z L;  4Y71 B;  4X8V L;  4OTY A;  3RR3 A;  2J4I B;  1IQK L;  1YGC L;  2J38 B;  2MGR A;  2WPH E;  2W2O E;  2BQW A;  3SOQ A;  1DIY A;  1MOX C;  2Y38 A;  2WPI E;  2FLR L;  2WYJ B;  1UZQ A;  2EI6 B;  1J9C L;  2PR3 B;  2W3K B;  1UZK A;  3KRK A;  4ZH8 B;  1HRE A;  2H9E C;  4G1M B;  1APQ A;  3SOV A;  3LN1 A;  3QCW A;  2TGF A;  1CCV A;  2W2P E;  4BTI A;  4XLW A;  4E1G A;  1IQG L;  1FFM A;  2W26 B;  1JBU L;  2AYL A;  2WG4 B;  3ENS A;  2WFX B;  5KIR A;  3KQB L;  4JYV L;  3CS7 L;  1V1H A;  1ADX A;  4ISI L;  3V64 C;  2HOX A;  1TLE A;  1HZ8 A;  1B9W A;  3HS5 A;  1EPG A;  3FFG L;  4BXS A;  4JYU L;  1HRF A;  3GCW E;  2WFT A;  2RNL A;  1LPG A;  5IKR A;  2BQ6 A;  1FF7 A;  1PFX L;  4JZF L;  5FDQ A;  1IQN L;  4CSY A;  2PHB B;  4BTT A;  2ADX A;  4BDX A;  2EI8 B;  2P3U A;  3N8Y B;  2BQ7 A;  3MQE A;  2Y5H L;  1LMJ A;  5IKT A;  1LPK A;  2Y81 B;  4A94 C;  2XBX L;  1OB1 C;  3R05 A;  1G1S A;  1APO A;  5IKV A;  1IQI L;  1EAI C;  5JBB E;  3TH3 L;  1PTH A;  2WPL E;  3LC5 B;  1YUG A;  4Y76 B;  4M11 A;  2VVV L;  3CFW A;  1JV2 B;  5CIS A;  2WPM E;  4ZXX L;  2Y5G L;  1F7E A;  1EPI A;  4D90 A;  4Z6A L;  1DDX A;  4ZXY L;  1HT8 A;  1G1Q A;  1IVO C;  3OLU A;  5L2Y L;  2P95 L;  4RS0 A;  5CKN A;  3EGF A;  4ISH L;  3M37 L;  3KQE L;  1G1R A;  1HAF A;  4ZHA B;  3NJP C;  3S6X A;  1KIG L;  1YO8 A;  4COX A;  2WG3 C;  2BOK L;  1LMM A;  1XKB A;  4AQT A;  2J34 B;  2VH6 B;  5CKQ A;  4CUD A;  1KSN B;  1F0R B;  2P3F L;  1Z6C A;  4RUT A;  1I0U A;  4NA9 L;  1DX5 I;  3SW2 A;  1CVU A;  3F6U L;  3GIS X;  2RHP A;  2VRS A;  3NTB A;  1W7X L;  3FCS B;  1WU1 B;  2XBY L;  2JJL A;  1IQE L;  4ZAE B;  2YGP A;  2BSF A;  1DVA L;  4PH9 A;  2KV4 A;  5L30 L;  3NT1 A;  3NTG A;  1LQD A;  2M74 A;  5KN5 C;  2Y7X B;  1DQB A;  1NFY B;  1O5D L;  4YZU B;  2PUQ L;  3TBD A;  1FSB A;  4XL1 A;  3Q7D A;  1ATD A;  4YT6 L;  5E8D A;  4RRY A;  4NG9 L;  1EMN A;  1YUF A;  4X8S L;  1KLJ L;  4BXW A;  3U7U G;  3IJE B;  4FM5 A;  3TK6 B;  2W2N E;  4JZD L;  1AUT L;  1XKA L;  3N8Z A;  4RRX A;  5F19 A;  1FJS L;  2P28 B;  5JB8 E;  1CQE A;  2W3I B;  1QFK L;  2P3T A;  1HJ7 A;  4Y79 B;  2VJ3 A;  1PRH A;  4C16 A;  5JVY A;  2WYG B;  1IP0 A;  2BO2 A;  2Y80 B;  1HT5 A;  3HS7 A;  3IIT B;  2Y5F L;  3HO4 A;  2JKH L;  1SZB A;  1U67 A;  1NFW B;  3HS6 A;  1NFX B;  1UZP A;  1EBV A;  3N8X A;  3C9A C;  1X7A L;  3ZYJ B;  4GU3 A;  2BOX A;  3ZYI B;  2W2M E;  4Z0L A;  1UZJ A;  3PGH A;  5JBA E;  2G00 L;  2J94 B;  1N7D A;  1XDT R;  4BTU A;  3CA7 A;  1NFU B;  1P0S L;  2BMG A;  2P26 A;  1PGE A;  1IOE L;  1Q4G A;  1K36 A;  1P9J A;  2WPK E;  3BT2 A;  1M1X B;  2VVU L;  1URK A;  1XFE A;  1IQJ L;  4Y6D B;  2D1J B;  3HPT A;  1CVW L;  3OLT A;  2P94 L;  3M36 L;  5JVZ A;  4MMZ B;  1HX2 A;  1V3X B;  1W8B L;  3N8Y A;  5IKQ A;  4Z0K B;  4YT7 L;  1KLO A;  3BT1 A;  4GU4 A;  4MMX B;  4Y7A B;  2VH0 B;  3KQD L;  1IGX A;  1IQL L;  3BPS E;  3DEM A;  1NT0 A;  1EQH A;  1NPE B;  1MQ5 L;  2KL7 A;  1ATE A;  2I9B A;  3HO3 A;  4O02 B;  4XBM A;  2RA0 L;  1EMO A;  2B7D L;  1QIU A;  4A7I A;  3QMO A;  3SOB B;  2VWN L;  1GK5 A;  2NPR A;  1WHF A;  2BOU A;  4MMY B;  3MDL A;  1MQ6 L;  4Y7B B;  2EI7 B;  1IOX A;  2VWM K;  2BT8 A;  3LTG D;  1TPG A;  1KLI L;  1F0S B;  2GD4 A;  4TGF A;  4D0F A;  4X8U L;  2YGO A;  5JB9 E;  3TGF A;  2F9B L;  1C5M F;  1ATB A;  1WHE A;  4RRW A;  5K0H B;  3LN0 A;  2UWL B;  3F1S B;  4JZE L;  3QH0 A;  3LIW B;  1ATA A;  2KB9 A;  1IQH L;  1K37 A;  2FLB L;  2VWL L;  4CUE A;  2W2Q E;  2Y82 B;  2KNI A;  3GCX E;  1IJQ A;  1EPJ A;  3ELA L;  1YUK B;  2XC0 L;  2OYU P;  5JBC E;  1F7M A;  1PXX A;  4RRZ A;  2FZZ L;  3N8W B;  1LK9 A;  3U73 A;  2MGP A;  2H9E L;  1EZQ B;  2P16 L;  2P3F N;  3ZYG A;  1V1I A;  1JL9 A;  3LAQ A;  4NGA L;  1ZAQ A;  2K2T A;  3P5B L;  2XC5 L;  2J95 B;  2Q1J B;  5F1A A;  1IGZ A;  2UWP B;  1G2M B;  2J2U B;  2MHP A;  2P93 L;  1A3P A;  2BT7 A;  3H5C B;  1BF9 A;  3FBY A;  2XBW L;  1FE2 A;  1LPZ A;  1HCG B;  5CKM A;  1CEJ A;  2WZP P;  5EGM B;  3CEN L;  1Z6E L;  2VVC K;  3KCG L;  1EQG A;  2K2S B;  2UWO B;  4LOR A;  4BDW A;  1EGF A;  1G1T A;  1NQL B;  3K9X A;  5COX A;  5I46 L;  3LTF B;  1FAK L;  1L5G B;  3ASI A;  3Q3K B;  4D0E A;  2OYE P;  3KQC L;  1CX2 A;  2XC4 L;  3TK5 B;  1KKE A;  3V65 B;  3N8W A;  1FAX L;  2W86 A;  4X8T L;  2WPJ E;  4CUF A;  1U8C B;  2I9A A; 
#chains in the Genus database with same CATH homology
 3KK6 A;  2YGQ A;  1NZI A;  3POY A;  2BZ6 L;  4OTJ A;  1IQF L;  1COU A;  1TOZ A;  4O1Z A;  2FD6 A;  1CCF A;  5JW1 A;  2Y7Z B;  1HAE A;  1EPH A;  3N8V A;  2FLG A;  3KL6 B;  3HO5 A;  1N1I A;  2CJI B;  2VWO L;  2BOH A;  3LC3 B;  2XBV L;  3TZI A;  1G2L B;  4LMF A;  1IQM L;  6COX A;  4M10 A;  1L3Y A;  2DDU A;  1RFN B;  5L2Z L;  4Y71 B;  4X8V L;  4OTY A;  3RR3 A;  2J4I B;  1IQK L;  1YGC L;  2J38 B;  2MGR A;  2WPH E;  2W2O E;  2BQW A;  3SOQ A;  1DIY A;  1MOX C;  2Y38 A;  2WPI E;  2FLR L;  2WYJ B;  1UZQ A;  2EI6 B;  1J9C L;  2PR3 B;  2W3K B;  1UZK A;  3KRK A;  4ZH8 B;  1HRE A;  2H9E C;  4G1M B;  1APQ A;  3SOV A;  3LN1 A;  3QCW A;  2TGF A;  1CCV A;  2W2P E;  4BTI A;  4XLW A;  4E1G A;  1IQG L;  1FFM A;  2W26 B;  1JBU L;  2AYL A;  2WG4 B;  3ENS A;  2WFX B;  5KIR A;  3KQB L;  4JYV L;  3CS7 L;  1ADX A;  4ISI L;  3V64 C;  1TLE A;  1HZ8 A;  1B9W A;  3HS5 A;  1EPG A;  3FFG L;  4BXS A;  4JYU L;  1HRF A;  3GCW E;  2WFT A;  2RNL A;  1LPG A;  5IKR A;  2BQ6 A;  1FF7 A;  1PFX L;  4JZF L;  5FDQ A;  1IQN L;  4CSY A;  2PHB B;  4BTT A;  2ADX A;  4BDX A;  2EI8 B;  2P3U A;  3N8Y B;  2BQ7 A;  3MQE A;  2Y5H L;  1LMJ A;  5IKT A;  1LPK A;  2Y81 B;  4A94 C;  2XBX L;  1OB1 C;  3R05 A;  1G1S A;  1APO A;  5IKV A;  1IQI L;  1EAI C;  5JBB E;  3TH3 L;  1PTH A;  2WPL E;  3LC5 B;  1YUG A;  4Y76 B;  4M11 A;  2VVV L;  3CFW A;  1JV2 B;  5CIS A;  2WPM E;  4ZXX L;  2Y5G L;  1F7E A;  1EPI A;  4D90 A;  4Z6A L;  1DDX A;  4ZXY L;  1HT8 A;  1G1Q A;  1IVO C;  3OLU A;  5L2Y L;  2P95 L;  4RS0 A;  5CKN A;  3EGF A;  4ISH L;  3M37 L;  3KQE L;  1G1R A;  1HAF A;  4ZHA B;  3NJP C;  3S6X A;  1KIG L;  1YO8 A;  4COX A;  2WG3 C;  2BOK L;  1LMM A;  1XKB A;  4AQT A;  2J34 B;  2VH6 B;  5CKQ A;  4CUD A;  1KSN B;  1F0R B;  2P3F L;  1Z6C A;  4RUT A;  1I0U A;  4NA9 L;  1DX5 I;  3SW2 A;  1CVU A;  3F6U L;  3GIS X;  2RHP A;  3NTB A;  1W7X L;  3FCS B;  1WU1 B;  2XBY L;  1IQE L;  4ZAE B;  2YGP A;  1DVA L;  4PH9 A;  2KV4 A;  5L30 L;  3NT1 A;  3NTG A;  1LQD A;  2M74 A;  5KN5 C;  2Y7X B;  1DQB A;  1NFY B;  1O5D L;  4YZU B;  2PUQ L;  3TBD A;  1FSB A;  4XL1 A;  3Q7D A;  1ATD A;  4YT6 L;  5E8D A;  4RRY A;  4NG9 L;  1EMN A;  1YUF A;  4X8S L;  1KLJ L;  4BXW A;  3U7U G;  3IJE B;  4FM5 A;  3TK6 B;  2W2N E;  4JZD L;  1AUT L;  1XKA L;  3N8Z A;  4RRX A;  5F19 A;  1FJS L;  2P28 B;  5JB8 E;  1CQE A;  2W3I B;  1QFK L;  2P3T A;  1HJ7 A;  4Y79 B;  2VJ3 A;  1PRH A;  4C16 A;  5JVY A;  2WYG B;  1IP0 A;  2BO2 A;  2Y80 B;  1HT5 A;  3HS7 A;  3IIT B;  2Y5F L;  3HO4 A;  2JKH L;  1SZB A;  1U67 A;  1NFW B;  3HS6 A;  1NFX B;  1UZP A;  1EBV A;  3N8X A;  3C9A C;  1X7A L;  3ZYJ B;  2BOX A;  3ZYI B;  2W2M E;  4Z0L A;  1UZJ A;  3PGH A;  5JBA E;  2G00 L;  2J94 B;  1N7D A;  1XDT R;  4BTU A;  3CA7 A;  1NFU B;  1P0S L;  2BMG A;  2P26 A;  1PGE A;  1IOE L;  1Q4G A;  1K36 A;  1P9J A;  2WPK E;  3BT2 A;  1M1X B;  2VVU L;  1URK A;  1XFE A;  1IQJ L;  4Y6D B;  2D1J B;  3HPT A;  1CVW L;  3OLT A;  2P94 L;  3M36 L;  5JVZ A;  4MMZ B;  1HX2 A;  1V3X B;  1W8B L;  3N8Y A;  5IKQ A;  4Z0K B;  4YT7 L;  1KLO A;  3BT1 A;  4MMX B;  4Y7A B;  2VH0 B;  3KQD L;  1IGX A;  1IQL L;  3BPS E;  3DEM A;  1NT0 A;  1EQH A;  1NPE B;  1MQ5 L;  2KL7 A;  1ATE A;  2I9B A;  3HO3 A;  4O02 B;  4XBM A;  2RA0 L;  1EMO A;  2B7D L;  4A7I A;  3QMO A;  3SOB B;  2VWN L;  1GK5 A;  2NPR A;  1WHF A;  2BOU A;  4MMY B;  3MDL A;  1MQ6 L;  4Y7B B;  2EI7 B;  1IOX A;  2VWM K;  3LTG D;  1TPG A;  1KLI L;  1F0S B;  2GD4 A;  4TGF A;  4D0F A;  4X8U L;  2YGO A;  5JB9 E;  3TGF A;  2F9B L;  1C5M F;  1ATB A;  1WHE A;  4RRW A;  5K0H B;  3LN0 A;  2UWL B;  3F1S B;  4JZE L;  3QH0 A;  3LIW B;  1ATA A;  2KB9 A;  1IQH L;  1K37 A;  2FLB L;  2VWL L;  4CUE A;  2W2Q E;  2Y82 B;  2KNI A;  3GCX E;  1IJQ A;  1EPJ A;  3ELA L;  1YUK B;  2XC0 L;  2OYU P;  5JBC E;  1F7M A;  1PXX A;  4RRZ A;  2FZZ L;  3N8W B;  3U73 A;  2MGP A;  2H9E L;  1EZQ B;  2P16 L;  2P3F N;  3ZYG A;  1JL9 A;  3LAQ A;  4NGA L;  1ZAQ A;  2K2T A;  3P5B L;  2XC5 L;  2J95 B;  2Q1J B;  5F1A A;  1IGZ A;  2UWP B;  1G2M B;  2J2U B;  2MHP A;  2P93 L;  1A3P A;  3H5C B;  1BF9 A;  3FBY A;  2XBW L;  1FE2 A;  1LPZ A;  1HCG B;  5CKM A;  1CEJ A;  2WZP P;  5EGM B;  3CEN L;  1Z6E L;  2VVC K;  3KCG L;  1EQG A;  2K2S B;  2UWO B;  4LOR A;  4BDW A;  1EGF A;  1G1T A;  1NQL B;  3K9X A;  5COX A;  5I46 L;  3LTF B;  1FAK L;  1L5G B;  3ASI A;  3Q3K B;  4D0E A;  2OYE P;  3KQC L;  1CX2 A;  2XC4 L;  3TK5 B;  3V65 B;  3N8W A;  1FAX L;  2W86 A;  4X8T L;  2WPJ E;  4CUF A;  1U8C B;  2I9A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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