4AOKB

Conformational dynamics of aspartate alpha-decarboxylase active site revealed by protein-ligand complexes: 1-methyl-l-aspartate complex
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
98
structure length
98
Chain Sequence
CAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Dynamics of Aspartate Alpha Decarboxylase Active Site Revealed by Protein-Ligand Complexes
rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords ASPARTATE 1-DECARBOXYLASE BETA CHAIN
total genus 24
structure length 98
sequence length 98
chains with identical sequence E
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2012-03-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4aokB00
1AA6A 1E5VA 2VPWA 5FTMA 3GTQA 1EU1A 1Y1WA 4DMRA 4AAYA 2YU9A 4KODA 1E60A 2EEOB 5DYIA 5FTJA 2PJHB 1G8JA 1QDNA 4KLNA 1SFOA 1VC3B 1WCMA 3GTMA 2JIMA 1TMOA 1H0HA 3HU1A 3IR5A 3ML1A 5T5ID 1I3QA 3HU3A 1PYUB 1UHDA 4CRZA 1Y1VA 5C18A 2NVYA 1R7RA 1QCSA 1TWFA 3QC8A 3GTPA 4CS0A 3GTJA 1AW8B 1G8KA 4GA5A 1TWCA 5FTNA 2NAPA 4D7ZB 3O5AA 1Y5IA 1E32A 5B6CA 5EPPA 2JIRA 2Y0SA 1UHEA 2R92A 2DMRA 4AONB 1WLFA 2IV2X 1H5NA 4CRYG 4RV0A 2V3VA 1TWAA 5GLFA 2V45A 1DMSA 1PQEA 3HU2A 5DYGA 5FTKA 2WB1A 2VUMA 1IW7D 5C1BA 2JA7A 1Y4ZA 5T5MD 4KDIA 1PQHA 2VPZA 4KDLA 3TIWA 1DMRA 3GTKA 3OUGA 1R27A 1Q16A 2WAQA 1TWHA 1E61A 2NYAA 3QWZA 1FDOA 3PLXB 3GTGA 2E2HA 1KQGA 1K83A 3HKZA 2E2IA 4GA6A 1KQFA 3DMRA 3H0GA 2VPXA 2R93A 1TWGA 2JIPA 3IR6A 2PMZA 5FTLA 1SIWA 1S3SA 3QQ8A 3GTLA 2NVXA 2JA6A 3QQ7A 1PPYA 4AZDA 4AYBA 2R7ZA 2JIOA 1PT1A 2VPYA 2JIQA 1PQFA 2B63A 1I50A 1R9TA 2KI8A 1FDIA 4KO8A 3TM7B 2C45A 1PYQA 1PT0A 2E7ZA 4C2MA 1CZ5A 1CR5A 1OGYA 4AOKB 2JA5A 3GTOA 1E18A 1YLEA 3CF2A 3CQZA 4QIWA 3IR7A 3FKIA 1CZ4A
chains in the Genus database with same CATH superfamily
1AA6A 1E5VA 2A68D 2VPWA 2GAEA 5FTMA 1BW3A 3GTQA 1EU1A 1Y1WA 2G6GA 4DMRA 4AAYA 2YU9A 2HCZX 4KODA 1E60A 2EEOB 5DYIA 5FTJA 2PJHB 1G8JA 1QDNA 1OA7A 4KLNA 1SFOA 1VC3B 4FFTA 5GLXA 1WCMA 4JP6A 2JIMA 1TMOA 3GTMA 1H0HA 3HU1A 3IR5A 3ML1A 5T5ID 4ENGA 1I3QA 3HU3A 1PYUB 1UHDA 4CRZA 1Y1VA 2AE0X 2NVYA 1R7RA 5C18A 1OA9A 1QCSA 1TWFA 3QC8A 3SULA 3GTPA 4CS0A 1HD5A 3GTJA 1AW8B 1G8KA 4GA5A 1TWCA 5FTNA 2NAPA 3X2GA 3D30A 3O5AA 1ZC1A 1Y5IA 4D7ZB 1E32A 5B6CA 5EPPA 2JIRA 2Y0SA 1YNJD 3SUMA 1UHEA 2R92A 2DMRA 4AONB 1WLFA 2IV2X 1H5NA 2PJJA 4CRYG 4FERA 4RV0A 2V3VA 1TWAA 4JP7A 5GLFA 2V45A 1DMSA 1PQEA 4FG4A 3HU2A 4JCWA 5DYGA 5FTKA 2PNWA 2WB1A 2VUMA 1IW7D 3SUJA 1YNND 5C1BA 2JA7A 1Y4ZA 2A69D 5T5MD 4KDIA 1PQHA 2VPZA 4KDLA 3TIWA 1DMRA 3GTKA 3OUGA 1ZYRD 3M3GA 1R27A 1Q16A 1CZ4A 3X2PA 3ENGA 1TWHA 2WAQA 1E61A 3X2OA 2NYAA 3QWZA 1FDOA 3PLXB 2KQAA 2YUJA 3X2KA 3GTGA 1WC2A 2E2HA 1KQGA 3X2MA 1K83A 3HKZA 4FG2A 2E2IA 4GA6A 2CW0D 1KQFA 3DMRA 3H0GA 2PI8A 2VPXA 4ZM7A 2A6ED 2R93A 1TWGA 2JIPA 3IR6A 2PMZA 1N10A 5FTLA 2O5JD 2ENGA 1SIWA 1S3SA 5GLYA 3QQ8A 3GTLA 2NVXA 1L8FA 2JA6A 3QQ7A 1PPYA 4AZDA 4JJOA 4AYBA 3X2LA 2R7ZA 5H4UA 3X2HA 2JIOA 3SUKA 3X2JA 4L48A 1PT1A 2PICA 2VPYA 2JIQA 1PQFA 4JS7A 2BH0A 2B63A 1I50A 1R9TA 1BW4A 2KI8A 1SMYD 1FDIA 2G5DA 4KO8A 3TM7B 5GM9A 2C45A 1PYQA 1PT0A 2E7ZA 4C2MA 1CZ5A 2A6HD 3X2IA 1CR5A 1OGYA 4AOKB 2JA5A 3GTOA 1E18A 1YLEA 3CF2A 3CQZA 3X2NA 3CZBA 4AVRA 4QIWA 3IR7A 3FKIA 4NOHA 2BE5D
chains in the Genus database with same CATH topology
1AA6A 1E5VA 2A68D 2VPWA 2GAEA 5FTMA 3GTQA 1EU1A 1Y1WA 2G6GA 4DMRA 4AAYA 2YU9A 4KODA 1E60A 2EEOB 5DYIA 5FTJA 2PJHB 1G8JA 1QDNA 4KLNA 1SFOA 1VC3B 1WCMA 3GTMA 2JIMA 1TMOA 1H0HA 3HU1A 3IR5A 3ML1A 5T5ID 1I3QA 3HU3A 1PYUB 1UHDA 4CRZA 1Y1VA 2AE0X 2NVYA 1R7RA 5C18A 1QCSA 1TWFA 3QC8A 3GTPA 4CS0A 3GTJA 1AW8B 1G8KA 4GA5A 1TWCA 5FTNA 2NAPA 4D7ZB 3O5AA 1ZC1A 1Y5IA 1E32A 5B6CA 5EPPA 2JIRA 2Y0SA 1YNJD 1UHEA 2R92A 2DMRA 4AONB 1WLFA 2IV2X 1H5NA 2PJJA 4CRYG 4RV0A 2V3VA 1TWAA 5GLFA 2V45A 1DMSA 1PQEA 3HU2A 5DYGA 5FTKA 2PNWA 2WB1A 2VUMA 1IW7D 1YNND 5C1BA 2JA7A 1Y4ZA 2A69D 5T5MD 4KDIA 1PQHA 2VPZA 4KDLA 3TIWA 1DMRA 3GTKA 3OUGA 1ZYRD 1R27A 1Q16A 1CZ4A 1TWHA 2WAQA 1E61A 2NYAA 3QWZA 1FDOA 3PLXB 2YUJA 3GTGA 2E2HA 1KQGA 1K83A 3HKZA 2E2IA 4GA6A 2CW0D 1KQFA 3DMRA 3H0GA 2PI8A 2VPXA 2A6ED 2R93A 1TWGA 2JIPA 3IR6A 2PMZA 5FTLA 2O5JD 1SIWA 1S3SA 3QQ8A 3GTLA 2NVXA 2JA6A 3QQ7A 1PPYA 4AZDA 4AYBA 2R7ZA 2JIOA 1PT1A 2PICA 2VPYA 2JIQA 1PQFA 2B63A 1I50A 1R9TA 2KI8A 1SMYD 1FDIA 2G5DA 4KO8A 3TM7B 2C45A 1PYQA 1PT0A 2E7ZA 4C2MA 1CZ5A 2A6HD 1CR5A 1OGYA 4AOKB 2JA5A 3GTOA 1E18A 1YLEA 3CF2A 3CQZA 3CZBA 4QIWA 3IR7A 3FKIA 4NOHA 2BE5D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AA6 A;  1E5V A;  2VPW A;  5FTM A;  3GTQ A;  1EU1 A;  1Y1W A;  4DMR A;  4AAY A;  2YU9 A;  4KOD A;  1E60 A;  2EEO B;  5DYI A;  5FTJ A;  2PJH B;  1G8J A;  1QDN A;  4KLN A;  1SFO A;  1VC3 B;  1WCM A;  3GTM A;  2JIM A;  1TMO A;  1H0H A;  3HU1 A;  3IR5 A;  3ML1 A;  5T5I D;  1I3Q A;  3HU3 A;  1PYU B;  1UHD A;  4CRZ A;  1Y1V A;  5C18 A;  2NVY A;  1R7R A;  1QCS A;  1TWF A;  3QC8 A;  3GTP A;  4CS0 A;  3GTJ A;  1AW8 B;  1G8K A;  4GA5 A;  1TWC A;  5FTN A;  2NAP A;  4D7Z B;  3O5A A;  1Y5I A;  1E32 A;  5B6C A;  5EPP A;  2JIR A;  2Y0S A;  1UHE A;  2R92 A;  2DMR A;  4AON B;  1WLF A;  2IV2 X;  1H5N A;  4CRY G;  4RV0 A;  2V3V A;  1TWA A;  5GLF A;  2V45 A;  1DMS A;  1PQE A;  3HU2 A;  5DYG A;  5FTK A;  2WB1 A;  2VUM A;  1IW7 D;  5C1B A;  2JA7 A;  1Y4Z A;  5T5M D;  4KDI A;  1PQH A;  2VPZ A;  4KDL A;  3TIW A;  1DMR A;  3GTK A;  3OUG A;  1R27 A;  1Q16 A;  2WAQ A;  1TWH A;  1E61 A;  2NYA A;  3QWZ A;  1FDO A;  3PLX B;  3GTG A;  2E2H A;  1KQG A;  1K83 A;  3HKZ A;  2E2I A;  4GA6 A;  1KQF A;  3DMR A;  3H0G A;  2VPX A;  2R93 A;  1TWG A;  2JIP A;  3IR6 A;  2PMZ A;  5FTL A;  1SIW A;  1S3S A;  3QQ8 A;  3GTL A;  2NVX A;  2JA6 A;  3QQ7 A;  1PPY A;  4AZD A;  4AYB A;  2R7Z A;  2JIO A;  1PT1 A;  2VPY A;  2JIQ A;  1PQF A;  2B63 A;  1I50 A;  1R9T A;  2KI8 A;  1FDI A;  4KO8 A;  3TM7 B;  2C45 A;  1PYQ A;  1PT0 A;  2E7Z A;  4C2M A;  1CZ5 A;  1CR5 A;  1OGY A;  4AOK B;  2JA5 A;  3GTO A;  1E18 A;  1YLE A;  3CF2 A;  3CQZ A;  4QIW A;  3IR7 A;  3FKI A;  1CZ4 A; 
#chains in the Genus database with same CATH topology
 1AA6 A;  1E5V A;  2A68 D;  2VPW A;  2GAE A;  5FTM A;  1BW3 A;  3GTQ A;  1EU1 A;  1Y1W A;  2G6G A;  4DMR A;  4AAY A;  2YU9 A;  2HCZ X;  4KOD A;  1E60 A;  2EEO B;  5DYI A;  5FTJ A;  2PJH B;  1G8J A;  1QDN A;  1OA7 A;  4KLN A;  1SFO A;  1VC3 B;  4FFT A;  5GLX A;  1WCM A;  4JP6 A;  2JIM A;  1TMO A;  3GTM A;  1H0H A;  3HU1 A;  3IR5 A;  3ML1 A;  5T5I D;  4ENG A;  1I3Q A;  3HU3 A;  1PYU B;  1UHD A;  4CRZ A;  1Y1V A;  2AE0 X;  2NVY A;  1R7R A;  5C18 A;  1OA9 A;  1QCS A;  1TWF A;  3QC8 A;  3SUL A;  3GTP A;  4CS0 A;  1HD5 A;  3GTJ A;  1AW8 B;  1G8K A;  4GA5 A;  1TWC A;  5FTN A;  2NAP A;  3X2G A;  3D30 A;  3O5A A;  1ZC1 A;  1Y5I A;  4D7Z B;  1E32 A;  5B6C A;  5EPP A;  2JIR A;  2Y0S A;  1YNJ D;  3SUM A;  1UHE A;  2R92 A;  2DMR A;  4AON B;  1WLF A;  2IV2 X;  1H5N A;  2PJJ A;  4CRY G;  4FER A;  4RV0 A;  2V3V A;  1TWA A;  4JP7 A;  5GLF A;  2V45 A;  1DMS A;  1PQE A;  4FG4 A;  3HU2 A;  4JCW A;  5DYG A;  5FTK A;  2PNW A;  2WB1 A;  2VUM A;  1IW7 D;  3SUJ A;  1YNN D;  5C1B A;  2JA7 A;  1Y4Z A;  2A69 D;  5T5M D;  4KDI A;  1PQH A;  2VPZ A;  4KDL A;  3TIW A;  1DMR A;  3GTK A;  3OUG A;  1ZYR D;  3M3G A;  1R27 A;  1Q16 A;  1CZ4 A;  3X2P A;  3ENG A;  1TWH A;  2WAQ A;  1E61 A;  3X2O A;  2NYA A;  3QWZ A;  1FDO A;  3PLX B;  2KQA A;  2YUJ A;  3X2K A;  3GTG A;  1WC2 A;  2E2H A;  1KQG A;  3X2M A;  1K83 A;  3HKZ A;  4FG2 A;  2E2I A;  4GA6 A;  2CW0 D;  1KQF A;  3DMR A;  3H0G A;  2PI8 A;  2VPX A;  4ZM7 A;  2A6E D;  2R93 A;  1TWG A;  2JIP A;  3IR6 A;  2PMZ A;  1N10 A;  5FTL A;  2O5J D;  2ENG A;  1SIW A;  1S3S A;  5GLY A;  3QQ8 A;  3GTL A;  2NVX A;  1L8F A;  2JA6 A;  3QQ7 A;  1PPY A;  4AZD A;  4JJO A;  4AYB A;  3X2L A;  2R7Z A;  5H4U A;  3X2H A;  2JIO A;  3SUK A;  3X2J A;  4L48 A;  1PT1 A;  2PIC A;  2VPY A;  2JIQ A;  1PQF A;  4JS7 A;  2BH0 A;  2B63 A;  1I50 A;  1R9T A;  1BW4 A;  2KI8 A;  1SMY D;  1FDI A;  2G5D A;  4KO8 A;  3TM7 B;  5GM9 A;  2C45 A;  1PYQ A;  1PT0 A;  2E7Z A;  4C2M A;  1CZ5 A;  2A6H D;  3X2I A;  1CR5 A;  1OGY A;  4AOK B;  2JA5 A;  3GTO A;  1E18 A;  1YLE A;  3CF2 A;  3CQZ A;  3X2N A;  3CZB A;  4AVR A;  4QIW A;  3IR7 A;  3FKI A;  4NOH A;  2BE5 D; 
#chains in the Genus database with same CATH homology
 1AA6 A;  1E5V A;  2A68 D;  2VPW A;  2GAE A;  5FTM A;  3GTQ A;  1EU1 A;  1Y1W A;  2G6G A;  4DMR A;  4AAY A;  2YU9 A;  4KOD A;  1E60 A;  2EEO B;  5DYI A;  5FTJ A;  2PJH B;  1G8J A;  1QDN A;  4KLN A;  1SFO A;  1VC3 B;  1WCM A;  3GTM A;  2JIM A;  1TMO A;  1H0H A;  3HU1 A;  3IR5 A;  3ML1 A;  5T5I D;  1I3Q A;  3HU3 A;  1PYU B;  1UHD A;  4CRZ A;  1Y1V A;  2AE0 X;  2NVY A;  1R7R A;  5C18 A;  1QCS A;  1TWF A;  3QC8 A;  3GTP A;  4CS0 A;  3GTJ A;  1AW8 B;  1G8K A;  4GA5 A;  1TWC A;  5FTN A;  2NAP A;  4D7Z B;  3O5A A;  1ZC1 A;  1Y5I A;  1E32 A;  5B6C A;  5EPP A;  2JIR A;  2Y0S A;  1YNJ D;  1UHE A;  2R92 A;  2DMR A;  4AON B;  1WLF A;  2IV2 X;  1H5N A;  2PJJ A;  4CRY G;  4RV0 A;  2V3V A;  1TWA A;  5GLF A;  2V45 A;  1DMS A;  1PQE A;  3HU2 A;  5DYG A;  5FTK A;  2PNW A;  2WB1 A;  2VUM A;  1IW7 D;  1YNN D;  5C1B A;  2JA7 A;  1Y4Z A;  2A69 D;  5T5M D;  4KDI A;  1PQH A;  2VPZ A;  4KDL A;  3TIW A;  1DMR A;  3GTK A;  3OUG A;  1ZYR D;  1R27 A;  1Q16 A;  1CZ4 A;  1TWH A;  2WAQ A;  1E61 A;  2NYA A;  3QWZ A;  1FDO A;  3PLX B;  2YUJ A;  3GTG A;  2E2H A;  1KQG A;  1K83 A;  3HKZ A;  2E2I A;  4GA6 A;  2CW0 D;  1KQF A;  3DMR A;  3H0G A;  2PI8 A;  2VPX A;  2A6E D;  2R93 A;  1TWG A;  2JIP A;  3IR6 A;  2PMZ A;  5FTL A;  2O5J D;  1SIW A;  1S3S A;  3QQ8 A;  3GTL A;  2NVX A;  2JA6 A;  3QQ7 A;  1PPY A;  4AZD A;  4AYB A;  2R7Z A;  2JIO A;  1PT1 A;  2PIC A;  2VPY A;  2JIQ A;  1PQF A;  2B63 A;  1I50 A;  1R9T A;  2KI8 A;  1SMY D;  1FDI A;  2G5D A;  4KO8 A;  3TM7 B;  2C45 A;  1PYQ A;  1PT0 A;  2E7Z A;  4C2M A;  1CZ5 A;  2A6H D;  1CR5 A;  1OGY A;  4AOK B;  2JA5 A;  3GTO A;  1E18 A;  1YLE A;  3CF2 A;  3CQZ A;  3CZB A;  4QIW A;  3IR7 A;  3FKI A;  4NOH A;  2BE5 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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