4AONB

Conformational dynamics of aspartate alpha-decarboxylase active site revealed by protein-ligand complexes: 1-methyl-l-aspartate complex
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
97
structure length
97
Chain Sequence
CAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Dynamics of Aspartate Alpha Decarboxylase Active Site Revealed by Protein-Ligand Complexes
rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords ASPARTATE-ALPHA-DECARBOXYLASE BETA CHAIN
total genus 23
structure length 97
sequence length 97
chains with identical sequence E
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2012-03-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4aonB00
3QQ7A 4CRYG 4D7ZB 2YU9A 2VPYA 1Y5IA 4KODA 3GTMA 1Y1WA 1CR5A 2VUMA 3HU3A 3HU2A 3GTOA 4RV0A 1WLFA 5T5MD 1KQGA 1PYUB 1PYQA 5B6CA 2VPZA 1H5NA 1PQFA 5C1BA 5EPPA 2B63A 3TIWA 1FDIA 1UHDA 3FKIA 1TWFA 1CZ5A 1R7RA 1PQEA 3IR7A 1I3QA 3IR5A 3H0GA 3GTQA 3HU1A 1E5VA 1TWAA 2EEOB 5FTMA 4GA5A 1PPYA 4C2MA 1CZ4A 1G8KA 1QDNA 3ML1A 1SIWA 2VPWA 1DMRA 1E60A 1E61A 1Y4ZA 2PJHB 1TWHA 2Y0SA 3CF2A 4KLNA 5T5ID 5FTJA 3QWZA 2R7ZA 1OGYA 1R9TA 1TMOA 2E2HA 3QC8A 5GLFA 3DMRA 4CRZA 4KO8A 2JA6A 1R27A 4AONB 4AYBA 1PT1A 1S3SA 2V3VA 1Q16A 2V45A 2JIMA 2NAPA 1K83A 5FTKA 1AW8B 2R93A 2JA5A 2NVYA 3QQ8A 2E2IA 1YLEA 2WB1A 1I50A 4AAYA 5FTNA 3OUGA 4CS0A 3GTKA 1H0HA 1PT0A 3GTJA 2R92A 5FTLA 1DMSA 2WAQA 3TM7B 4AZDA 4QIWA 5DYIA 1AA6A 2VPXA 1EU1A 1G8JA 1E18A 3HKZA 3O5AA 2NYAA 4KDLA 1TWGA 2KI8A 3IR6A 2DMRA 1QCSA 4DMRA 2JIRA 2JIQA 1E32A 2JIOA 3CQZA 4AOKB 1KQFA 5DYGA 2E7ZA 2PMZA 1Y1VA 1IW7D 1UHEA 1TWCA 1VC3B 3GTGA 1PQHA 4KDIA 2C45A 3GTLA 2JIPA 1FDOA 3PLXB 2IV2X 1SFOA 3GTPA 1WCMA 4GA6A 2NVXA 2JA7A 5C18A
chains in the Genus database with same CATH superfamily
3QQ7A 4CRYG 5GM9A 3X2LA 1YNND 4D7ZB 2YU9A 2VPYA 1Y5IA 4KODA 1YNJD 3GTMA 1Y1WA 2CW0D 1CR5A 3CZBA 3HU3A 2HCZX 3HU2A 3SUMA 2VUMA 3GTOA 4RV0A 2BE5D 1WLFA 4L48A 5T5MD 1KQGA 1PYUB 1PYQA 5B6CA 1ZC1A 1N10A 2VPZA 1H5NA 1PQFA 5C1BA 4FG4A 5EPPA 2B63A 3TIWA 1FDIA 1OA9A 4NOHA 3X2KA 1UHDA 2KQAA 3FKIA 1TWFA 1BW3A 4JP7A 1CZ5A 4JJOA 1R7RA 1PQEA 3IR7A 3X2OA 4JS7A 3IR5A 4ZM7A 3H0GA 1I3QA 4FG2A 3GTQA 3HU1A 1E5VA 1TWAA 2EEOB 5FTMA 1SMYD 3X2IA 3X2PA 3SULA 4GA5A 3SUJA 1PPYA 4C2MA 1CZ4A 1HD5A 1G8KA 1QDNA 3ML1A 4AVRA 1SIWA 2VPWA 1DMRA 1E60A 1E61A 1Y4ZA 2PJHB 1TWHA 2Y0SA 3CF2A 2G6GA 4KLNA 5T5ID 5FTJA 3QWZA 3M3GA 2R7ZA 1BW4A 1OGYA 1R9TA 1TMOA 2E2HA 3QC8A 5GLFA 3DMRA 3ENGA 4CRZA 4JP6A 4KO8A 3X2MA 2JA6A 1R27A 4AONB 4AYBA 1PT1A 1S3SA 2V3VA 1Q16A 2BH0A 3X2NA 2V45A 2JIMA 2A69D 2NAPA 4FERA 3X2JA 1K83A 5FTKA 1AW8B 2R93A 2JA5A 2NVYA 3QQ8A 2E2IA 1YLEA 2WB1A 1I50A 4AAYA 5FTNA 3OUGA 4CS0A 3GTKA 1H0HA 1PT0A 3GTJA 2R92A 5FTLA 1DMSA 3SUKA 2WAQA 1L8FA 2ENGA 4ENGA 2AE0X 5H4UA 3TM7B 3D30A 4AZDA 4QIWA 5DYIA 1AA6A 2VPXA 5GLXA 1EU1A 1G8JA 2A6HD 1E18A 2YUJA 3HKZA 1WC2A 3O5AA 4JCWA 3X2GA 2NYAA 4KDLA 1TWGA 2KI8A 2PICA 3IR6A 1ZYRD 2A6ED 2DMRA 1QCSA 4DMRA 2JIRA 2JIQA 1E32A 2JIOA 3CQZA 4AOKB 4FFTA 2PNWA 5GLYA 1KQFA 5DYGA 2E7ZA 2PMZA 1Y1VA 3X2HA 2GAEA 1IW7D 1UHEA 1TWCA 2PI8A 1VC3B 2O5JD 3GTGA 1PQHA 4KDIA 2C45A 1OA7A 3GTLA 2JIPA 1FDOA 3PLXB 2IV2X 1SFOA 3GTPA 1WCMA 2A68D 4GA6A 2PJJA 2NVXA 2G5DA 2JA7A 5C18A
chains in the Genus database with same CATH topology
3QQ7A 4CRYG 1YNND 4D7ZB 2YU9A 2VPYA 1Y5IA 4KODA 1YNJD 3GTMA 1Y1WA 2CW0D 1CR5A 3CZBA 3HU3A 3HU2A 2VUMA 3GTOA 4RV0A 2BE5D 1WLFA 5T5MD 1KQGA 1PYUB 1PYQA 5B6CA 1ZC1A 2VPZA 1H5NA 1PQFA 5C1BA 5EPPA 2B63A 3TIWA 1FDIA 4NOHA 1UHDA 3FKIA 1TWFA 1CZ5A 1R7RA 1PQEA 3IR7A 1I3QA 3IR5A 3H0GA 3GTQA 3HU1A 1E5VA 1TWAA 2EEOB 5FTMA 1SMYD 4GA5A 1PPYA 4C2MA 1CZ4A 1G8KA 1QDNA 3ML1A 1SIWA 2VPWA 1DMRA 1E60A 1E61A 1Y4ZA 2PJHB 1TWHA 2Y0SA 3CF2A 2G6GA 4KLNA 5T5ID 5FTJA 3QWZA 2R7ZA 1OGYA 1R9TA 1TMOA 2E2HA 3QC8A 5GLFA 3DMRA 4CRZA 4KO8A 2JA6A 1R27A 4AONB 4AYBA 1PT1A 1S3SA 2V3VA 1Q16A 2V45A 2JIMA 2A69D 2NAPA 1K83A 5FTKA 1AW8B 2R93A 2JA5A 2NVYA 3QQ8A 2E2IA 1YLEA 2WB1A 1I50A 4AAYA 5FTNA 3OUGA 4CS0A 3GTKA 1H0HA 1PT0A 3GTJA 2R92A 5FTLA 1DMSA 2WAQA 2AE0X 3TM7B 4AZDA 4QIWA 5DYIA 1AA6A 2VPXA 1EU1A 1G8JA 2A6HD 1E18A 2YUJA 3HKZA 3O5AA 2NYAA 4KDLA 1TWGA 2KI8A 2PICA 3IR6A 1ZYRD 2A6ED 2DMRA 1QCSA 4DMRA 2JIRA 2JIQA 1E32A 2JIOA 3CQZA 4AOKB 2PNWA 1KQFA 5DYGA 2E7ZA 2PMZA 1Y1VA 2GAEA 1IW7D 1UHEA 1TWCA 2PI8A 1VC3B 2O5JD 3GTGA 1PQHA 4KDIA 2C45A 3GTLA 2JIPA 1FDOA 3PLXB 2IV2X 1SFOA 3GTPA 1WCMA 2A68D 4GA6A 2PJJA 2NVXA 2G5DA 2JA7A 5C18A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QQ7 A;  4CRY G;  4D7Z B;  2YU9 A;  2VPY A;  1Y5I A;  4KOD A;  3GTM A;  1Y1W A;  1CR5 A;  2VUM A;  3HU3 A;  3HU2 A;  3GTO A;  4RV0 A;  1WLF A;  5T5M D;  1KQG A;  1PYU B;  1PYQ A;  5B6C A;  2VPZ A;  1H5N A;  1PQF A;  5C1B A;  5EPP A;  2B63 A;  3TIW A;  1FDI A;  1UHD A;  3FKI A;  1TWF A;  1CZ5 A;  1R7R A;  1PQE A;  3IR7 A;  1I3Q A;  3IR5 A;  3H0G A;  3GTQ A;  3HU1 A;  1E5V A;  1TWA A;  2EEO B;  5FTM A;  4GA5 A;  1PPY A;  4C2M A;  1CZ4 A;  1G8K A;  1QDN A;  3ML1 A;  1SIW A;  2VPW A;  1DMR A;  1E60 A;  1E61 A;  1Y4Z A;  2PJH B;  1TWH A;  2Y0S A;  3CF2 A;  4KLN A;  5T5I D;  5FTJ A;  3QWZ A;  2R7Z A;  1OGY A;  1R9T A;  1TMO A;  2E2H A;  3QC8 A;  5GLF A;  3DMR A;  4CRZ A;  4KO8 A;  2JA6 A;  1R27 A;  4AON B;  4AYB A;  1PT1 A;  1S3S A;  2V3V A;  1Q16 A;  2V45 A;  2JIM A;  2NAP A;  1K83 A;  5FTK A;  1AW8 B;  2R93 A;  2JA5 A;  2NVY A;  3QQ8 A;  2E2I A;  1YLE A;  2WB1 A;  1I50 A;  4AAY A;  5FTN A;  3OUG A;  4CS0 A;  3GTK A;  1H0H A;  1PT0 A;  3GTJ A;  2R92 A;  5FTL A;  1DMS A;  2WAQ A;  3TM7 B;  4AZD A;  4QIW A;  5DYI A;  1AA6 A;  2VPX A;  1EU1 A;  1G8J A;  1E18 A;  3HKZ A;  3O5A A;  2NYA A;  4KDL A;  1TWG A;  2KI8 A;  3IR6 A;  2DMR A;  1QCS A;  4DMR A;  2JIR A;  2JIQ A;  1E32 A;  2JIO A;  3CQZ A;  4AOK B;  1KQF A;  5DYG A;  2E7Z A;  2PMZ A;  1Y1V A;  1IW7 D;  1UHE A;  1TWC A;  1VC3 B;  3GTG A;  1PQH A;  4KDI A;  2C45 A;  3GTL A;  2JIP A;  1FDO A;  3PLX B;  2IV2 X;  1SFO A;  3GTP A;  1WCM A;  4GA6 A;  2NVX A;  2JA7 A;  5C18 A; 
#chains in the Genus database with same CATH topology
 3QQ7 A;  4CRY G;  5GM9 A;  3X2L A;  1YNN D;  4D7Z B;  2YU9 A;  2VPY A;  1Y5I A;  4KOD A;  1YNJ D;  3GTM A;  1Y1W A;  2CW0 D;  1CR5 A;  3CZB A;  3HU3 A;  2HCZ X;  3HU2 A;  3SUM A;  2VUM A;  3GTO A;  4RV0 A;  2BE5 D;  1WLF A;  4L48 A;  5T5M D;  1KQG A;  1PYU B;  1PYQ A;  5B6C A;  1ZC1 A;  1N10 A;  2VPZ A;  1H5N A;  1PQF A;  5C1B A;  4FG4 A;  5EPP A;  2B63 A;  3TIW A;  1FDI A;  1OA9 A;  4NOH A;  3X2K A;  1UHD A;  2KQA A;  3FKI A;  1TWF A;  1BW3 A;  4JP7 A;  1CZ5 A;  4JJO A;  1R7R A;  1PQE A;  3IR7 A;  3X2O A;  4JS7 A;  3IR5 A;  4ZM7 A;  3H0G A;  1I3Q A;  4FG2 A;  3GTQ A;  3HU1 A;  1E5V A;  1TWA A;  2EEO B;  5FTM A;  1SMY D;  3X2I A;  3X2P A;  3SUL A;  4GA5 A;  3SUJ A;  1PPY A;  4C2M A;  1CZ4 A;  1HD5 A;  1G8K A;  1QDN A;  3ML1 A;  4AVR A;  1SIW A;  2VPW A;  1DMR A;  1E60 A;  1E61 A;  1Y4Z A;  2PJH B;  1TWH A;  2Y0S A;  3CF2 A;  2G6G A;  4KLN A;  5T5I D;  5FTJ A;  3QWZ A;  3M3G A;  2R7Z A;  1BW4 A;  1OGY A;  1R9T A;  1TMO A;  2E2H A;  3QC8 A;  5GLF A;  3DMR A;  3ENG A;  4CRZ A;  4JP6 A;  4KO8 A;  3X2M A;  2JA6 A;  1R27 A;  4AON B;  4AYB A;  1PT1 A;  1S3S A;  2V3V A;  1Q16 A;  2BH0 A;  3X2N A;  2V45 A;  2JIM A;  2A69 D;  2NAP A;  4FER A;  3X2J A;  1K83 A;  5FTK A;  1AW8 B;  2R93 A;  2JA5 A;  2NVY A;  3QQ8 A;  2E2I A;  1YLE A;  2WB1 A;  1I50 A;  4AAY A;  5FTN A;  3OUG A;  4CS0 A;  3GTK A;  1H0H A;  1PT0 A;  3GTJ A;  2R92 A;  5FTL A;  1DMS A;  3SUK A;  2WAQ A;  1L8F A;  2ENG A;  4ENG A;  2AE0 X;  5H4U A;  3TM7 B;  3D30 A;  4AZD A;  4QIW A;  5DYI A;  1AA6 A;  2VPX A;  5GLX A;  1EU1 A;  1G8J A;  2A6H D;  1E18 A;  2YUJ A;  3HKZ A;  1WC2 A;  3O5A A;  4JCW A;  3X2G A;  2NYA A;  4KDL A;  1TWG A;  2KI8 A;  2PIC A;  3IR6 A;  1ZYR D;  2A6E D;  2DMR A;  1QCS A;  4DMR A;  2JIR A;  2JIQ A;  1E32 A;  2JIO A;  3CQZ A;  4AOK B;  4FFT A;  2PNW A;  5GLY A;  1KQF A;  5DYG A;  2E7Z A;  2PMZ A;  1Y1V A;  3X2H A;  2GAE A;  1IW7 D;  1UHE A;  1TWC A;  2PI8 A;  1VC3 B;  2O5J D;  3GTG A;  1PQH A;  4KDI A;  2C45 A;  1OA7 A;  3GTL A;  2JIP A;  1FDO A;  3PLX B;  2IV2 X;  1SFO A;  3GTP A;  1WCM A;  2A68 D;  4GA6 A;  2PJJ A;  2NVX A;  2G5D A;  2JA7 A;  5C18 A; 
#chains in the Genus database with same CATH homology
 3QQ7 A;  4CRY G;  1YNN D;  4D7Z B;  2YU9 A;  2VPY A;  1Y5I A;  4KOD A;  1YNJ D;  3GTM A;  1Y1W A;  2CW0 D;  1CR5 A;  3CZB A;  3HU3 A;  3HU2 A;  2VUM A;  3GTO A;  4RV0 A;  2BE5 D;  1WLF A;  5T5M D;  1KQG A;  1PYU B;  1PYQ A;  5B6C A;  1ZC1 A;  2VPZ A;  1H5N A;  1PQF A;  5C1B A;  5EPP A;  2B63 A;  3TIW A;  1FDI A;  4NOH A;  1UHD A;  3FKI A;  1TWF A;  1CZ5 A;  1R7R A;  1PQE A;  3IR7 A;  1I3Q A;  3IR5 A;  3H0G A;  3GTQ A;  3HU1 A;  1E5V A;  1TWA A;  2EEO B;  5FTM A;  1SMY D;  4GA5 A;  1PPY A;  4C2M A;  1CZ4 A;  1G8K A;  1QDN A;  3ML1 A;  1SIW A;  2VPW A;  1DMR A;  1E60 A;  1E61 A;  1Y4Z A;  2PJH B;  1TWH A;  2Y0S A;  3CF2 A;  2G6G A;  4KLN A;  5T5I D;  5FTJ A;  3QWZ A;  2R7Z A;  1OGY A;  1R9T A;  1TMO A;  2E2H A;  3QC8 A;  5GLF A;  3DMR A;  4CRZ A;  4KO8 A;  2JA6 A;  1R27 A;  4AON B;  4AYB A;  1PT1 A;  1S3S A;  2V3V A;  1Q16 A;  2V45 A;  2JIM A;  2A69 D;  2NAP A;  1K83 A;  5FTK A;  1AW8 B;  2R93 A;  2JA5 A;  2NVY A;  3QQ8 A;  2E2I A;  1YLE A;  2WB1 A;  1I50 A;  4AAY A;  5FTN A;  3OUG A;  4CS0 A;  3GTK A;  1H0H A;  1PT0 A;  3GTJ A;  2R92 A;  5FTL A;  1DMS A;  2WAQ A;  2AE0 X;  3TM7 B;  4AZD A;  4QIW A;  5DYI A;  1AA6 A;  2VPX A;  1EU1 A;  1G8J A;  2A6H D;  1E18 A;  2YUJ A;  3HKZ A;  3O5A A;  2NYA A;  4KDL A;  1TWG A;  2KI8 A;  2PIC A;  3IR6 A;  1ZYR D;  2A6E D;  2DMR A;  1QCS A;  4DMR A;  2JIR A;  2JIQ A;  1E32 A;  2JIO A;  3CQZ A;  4AOK B;  2PNW A;  1KQF A;  5DYG A;  2E7Z A;  2PMZ A;  1Y1V A;  2GAE A;  1IW7 D;  1UHE A;  1TWC A;  2PI8 A;  1VC3 B;  2O5J D;  3GTG A;  1PQH A;  4KDI A;  2C45 A;  3GTL A;  2JIP A;  1FDO A;  3PLX B;  2IV2 X;  1SFO A;  3GTP A;  1WCM A;  2A68 D;  4GA6 A;  2PJJ A;  2NVX A;  2G5D A;  2JA7 A;  5C18 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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