4AONB

Conformational dynamics of aspartate alpha-decarboxylase active site revealed by protein-ligand complexes: 1-methyl-l-aspartate complex
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
97
structure length
97
Chain Sequence
CAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Escherichia coli
publication title Conformational Dynamics of Aspartate Alpha Decarboxylase Active Site Revealed by Protein-Ligand Complexes
rcsb
molecule keywords ASPARTATE-ALPHA-DECARBOXYLASE BETA CHAIN
total genus 23
structure length 97
sequence length 97
chains with identical sequence E
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2012-03-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4aonB00
1PQHA 2E2HA 4KODA 4CRZA 3GTMA 4C2MA 4QIWA 2NYAA 1S3SA 2R92A 1KQGA 2NVYA 5B6CA 3GTGA 2JA7A 1K83A 1FDIA 2WB1A 1R27A 5T5ID 2NAPA 3HU2A 4AYBA 1IW7D 1PT0A 1FDOA 2VPWA 2VPXA 1G8KA 2JIPA 1WCMA 1I3QA 2E2IA 5FTNA 1QCSA 1PT1A 2JIOA 4AAYA 1PQFA 1E18A 1KQFA 3H0GA 2IV2X 2JIMA 2PJHB 2EEOB 1H0HA 1CZ5A 1AA6A 1I50A 5FTLA 3DMRA 3GTQA 1EU1A 3TIWA 2DMRA 3QC8A 1WLFA 5C18A 1E60A 3HU3A 3TM7B 1E32A 3O5AA 1DMSA 3IR6A 4GA6A 2Y0SA 5DYGA 1Y1VA 3GTJA 1R9TA 1TWGA 2JA5A 2JA6A 2YU9A 1DMRA 1E61A 1Y5IA 5FTKA 3GTLA 4RV0A 1TMOA 1OGYA 2VPZA 1R7RA 4D7ZB 1CR5A 2R93A 2PMZA 5GLFA 1YLEA 1TWFA 4DMRA 4GA5A 4CRYG 3QQ8A 1AW8B 2JIRA 5C1BA 1PYQA 1Y1WA 3IR7A 2V45A 1E5VA 1H5NA 2KI8A 4KDIA 1Q16A 1G8JA 3CF2A 4KO8A 2V3VA 5FTMA 3GTKA 4KLNA 1SFOA 1SIWA 5DYIA 5FTJA 3GTOA 1PQEA 3HU1A 1PPYA 1PYUB 4AONB 2VPYA 2NVXA 2WAQA 1UHDA 2B63A 4AZDA 1TWCA 3OUGA 1QDNA 2E7ZA 3FKIA 1VC3B 1UHEA 3HKZA 3ML1A 5T5MD 1TWHA 3IR5A 3QWZA 4KDLA 5EPPA 3QQ7A 3PLXB 2VUMA 1Y4ZA 2C45A 2R7ZA 3CQZA 2JIQA 1TWAA 4CS0A 4AOKB 1CZ4A 3GTPA
chains in the Genus database with same CATH superfamily
1PQHA 2E2HA 4KODA 4CRZA 1OA7A 3GTMA 4C2MA 4QIWA 2NYAA 1S3SA 4FERA 1KQGA 3ENGA 2R92A 2NVYA 5B6CA 3GTGA 2JA7A 1K83A 2HCZX 1FDIA 2WB1A 1R27A 2AE0X 5T5ID 2NAPA 3HU2A 3SULA 4AYBA 1IW7D 1PT0A 1FDOA 2VPWA 2VPXA 1G8KA 2JIPA 1WCMA 2G6GA 3X2IA 3CZBA 1I3QA 3X2OA 5FTNA 1QCSA 2YUJA 1PT1A 2E2IA 2JIOA 4AAYA 1PQFA 4FG2A 1E18A 1KQFA 3H0GA 2IV2X 2JIMA 2PJHB 2EEOB 1H0HA 4FG4A 1CZ5A 1AA6A 2A6ED 3X2NA 1I50A 5FTLA 3DMRA 3X2HA 4AVRA 3X2MA 3GTQA 1EU1A 3TIWA 2DMRA 2A68D 3QC8A 1SMYD 1WLFA 5C18A 1E60A 3HU3A 2ENGA 3X2LA 3TM7B 1E32A 3SUKA 3O5AA 1DMSA 3M3GA 3IR6A 2Y0SA 4GA6A 5DYGA 1ZC1A 1Y1VA 1BW3A 3GTJA 1L8FA 1R9TA 1TWGA 4JS7A 4JJOA 2JA5A 2JA6A 2YU9A 1DMRA 1E61A 1Y5IA 5FTKA 3GTLA 4RV0A 1TMOA 1OGYA 2VPZA 1R7RA 4JCWA 1CR5A 4D7ZB 5GLYA 4ZM7A 2GAEA 5H4UA 2R93A 2PMZA 5GLFA 1YLEA 4JP7A 1TWFA 3X2KA 3D30A 4DMRA 4GA5A 4CRYG 3QQ8A 1AW8B 3X2JA 2JIRA 5C1BA 4JP6A 2PNWA 1PYQA 2BE5D 4ENGA 1WC2A 1Y1WA 3IR7A 1YNJD 2V45A 1E5VA 4FFTA 1H5NA 5GM9A 2KI8A 4KDIA 1Q16A 4NOHA 1G8JA 1N10A 3CF2A 4KO8A 2V3VA 5FTMA 3GTKA 4KLNA 2O5JD 1SFOA 1SIWA 5DYIA 5FTJA 3GTOA 1PQEA 3HU1A 1PPYA 1PYUB 2BH0A 4AONB 2VPYA 3SUMA 2PJJA 1OA9A 2G5DA 3SUJA 2WAQA 2NVXA 2PICA 1UHDA 1YNND 5GLXA 2B63A 4AZDA 1TWCA 3OUGA 1QDNA 2E7ZA 3FKIA 1VC3B 1UHEA 3HKZA 3ML1A 5T5MD 1ZYRD 2A6HD 2PI8A 1TWHA 3IR5A 3QWZA 1HD5A 4KDLA 3QQ7A 5EPPA 3PLXB 4L48A 2KQAA 3X2PA 2A69D 2VUMA 1BW4A 1Y4ZA 2CW0D 2C45A 2R7ZA 3CQZA 2JIQA 1TWAA 4CS0A 4AOKB 1CZ4A 3GTPA 3X2GA
chains in the Genus database with same CATH topology
1PQHA 2E2HA 4KODA 4CRZA 3GTMA 4C2MA 4QIWA 2NYAA 1S3SA 2R92A 1KQGA 2NVYA 5B6CA 3GTGA 2JA7A 1K83A 1FDIA 2WB1A 1R27A 2AE0X 5T5ID 2NAPA 3HU2A 4AYBA 1IW7D 1PT0A 1FDOA 2VPWA 2VPXA 1G8KA 2JIPA 1WCMA 2G6GA 3CZBA 1I3QA 2E2IA 5FTNA 1QCSA 2YUJA 1PT1A 2JIOA 4AAYA 1PQFA 1E18A 1KQFA 3H0GA 2IV2X 2JIMA 2PJHB 2EEOB 1H0HA 1CZ5A 1AA6A 2A6ED 1I50A 5FTLA 3DMRA 3GTQA 1EU1A 3TIWA 2DMRA 2A68D 3QC8A 1SMYD 1WLFA 5C18A 1E60A 3HU3A 3TM7B 1E32A 3O5AA 1DMSA 3IR6A 4GA6A 2Y0SA 5DYGA 1ZC1A 1Y1VA 3GTJA 1R9TA 1TWGA 2JA5A 2JA6A 2YU9A 1DMRA 1E61A 1Y5IA 5FTKA 3GTLA 4RV0A 1TMOA 1OGYA 2VPZA 1R7RA 4D7ZB 1CR5A 2GAEA 2R93A 2PMZA 5GLFA 1YLEA 1TWFA 4DMRA 4GA5A 4CRYG 3QQ8A 1AW8B 2JIRA 5C1BA 2PNWA 1PYQA 2BE5D 1Y1WA 3IR7A 1YNJD 2V45A 1E5VA 1H5NA 2KI8A 4KDIA 1Q16A 4NOHA 1G8JA 3CF2A 4KO8A 2V3VA 5FTMA 3GTKA 4KLNA 2O5JD 1SFOA 1SIWA 5DYIA 5FTJA 3GTOA 1PQEA 3HU1A 1PPYA 1PYUB 4AONB 2VPYA 2PJJA 2G5DA 2NVXA 2WAQA 2PICA 1UHDA 1YNND 2B63A 4AZDA 1TWCA 3OUGA 1QDNA 2E7ZA 3FKIA 1VC3B 1UHEA 3HKZA 3ML1A 5T5MD 1ZYRD 2A6HD 2PI8A 1TWHA 3IR5A 3QWZA 4KDLA 5EPPA 3QQ7A 3PLXB 2A69D 2VUMA 1Y4ZA 2CW0D 2C45A 2R7ZA 3CQZA 2JIQA 1TWAA 4CS0A 4AOKB 1CZ4A 3GTPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PQH A;  2E2H A;  4KOD A;  4CRZ A;  3GTM A;  4C2M A;  4QIW A;  2NYA A;  1S3S A;  2R92 A;  1KQG A;  2NVY A;  5B6C A;  3GTG A;  2JA7 A;  1K83 A;  1FDI A;  2WB1 A;  1R27 A;  5T5I D;  2NAP A;  3HU2 A;  4AYB A;  1IW7 D;  1PT0 A;  1FDO A;  2VPW A;  2VPX A;  1G8K A;  2JIP A;  1WCM A;  1I3Q A;  2E2I A;  5FTN A;  1QCS A;  1PT1 A;  2JIO A;  4AAY A;  1PQF A;  1E18 A;  1KQF A;  3H0G A;  2IV2 X;  2JIM A;  2PJH B;  2EEO B;  1H0H A;  1CZ5 A;  1AA6 A;  1I50 A;  5FTL A;  3DMR A;  3GTQ A;  1EU1 A;  3TIW A;  2DMR A;  3QC8 A;  1WLF A;  5C18 A;  1E60 A;  3HU3 A;  3TM7 B;  1E32 A;  3O5A A;  1DMS A;  3IR6 A;  4GA6 A;  2Y0S A;  5DYG A;  1Y1V A;  3GTJ A;  1R9T A;  1TWG A;  2JA5 A;  2JA6 A;  2YU9 A;  1DMR A;  1E61 A;  1Y5I A;  5FTK A;  3GTL A;  4RV0 A;  1TMO A;  1OGY A;  2VPZ A;  1R7R A;  4D7Z B;  1CR5 A;  2R93 A;  2PMZ A;  5GLF A;  1YLE A;  1TWF A;  4DMR A;  4GA5 A;  4CRY G;  3QQ8 A;  1AW8 B;  2JIR A;  5C1B A;  1PYQ A;  1Y1W A;  3IR7 A;  2V45 A;  1E5V A;  1H5N A;  2KI8 A;  4KDI A;  1Q16 A;  1G8J A;  3CF2 A;  4KO8 A;  2V3V A;  5FTM A;  3GTK A;  4KLN A;  1SFO A;  1SIW A;  5DYI A;  5FTJ A;  3GTO A;  1PQE A;  3HU1 A;  1PPY A;  1PYU B;  4AON B;  2VPY A;  2NVX A;  2WAQ A;  1UHD A;  2B63 A;  4AZD A;  1TWC A;  3OUG A;  1QDN A;  2E7Z A;  3FKI A;  1VC3 B;  1UHE A;  3HKZ A;  3ML1 A;  5T5M D;  1TWH A;  3IR5 A;  3QWZ A;  4KDL A;  5EPP A;  3QQ7 A;  3PLX B;  2VUM A;  1Y4Z A;  2C45 A;  2R7Z A;  3CQZ A;  2JIQ A;  1TWA A;  4CS0 A;  4AOK B;  1CZ4 A;  3GTP A; 
#chains in the Genus database with same CATH topology
 1PQH A;  2E2H A;  4KOD A;  4CRZ A;  1OA7 A;  3GTM A;  4C2M A;  4QIW A;  2NYA A;  1S3S A;  4FER A;  1KQG A;  3ENG A;  2R92 A;  2NVY A;  5B6C A;  3GTG A;  2JA7 A;  1K83 A;  2HCZ X;  1FDI A;  2WB1 A;  1R27 A;  2AE0 X;  5T5I D;  2NAP A;  3HU2 A;  3SUL A;  4AYB A;  1IW7 D;  1PT0 A;  1FDO A;  2VPW A;  2VPX A;  1G8K A;  2JIP A;  1WCM A;  2G6G A;  3X2I A;  3CZB A;  1I3Q A;  3X2O A;  5FTN A;  1QCS A;  2YUJ A;  1PT1 A;  2E2I A;  2JIO A;  4AAY A;  1PQF A;  4FG2 A;  1E18 A;  1KQF A;  3H0G A;  2IV2 X;  2JIM A;  2PJH B;  2EEO B;  1H0H A;  4FG4 A;  1CZ5 A;  1AA6 A;  2A6E D;  3X2N A;  1I50 A;  5FTL A;  3DMR A;  3X2H A;  4AVR A;  3X2M A;  3GTQ A;  1EU1 A;  3TIW A;  2DMR A;  2A68 D;  3QC8 A;  1SMY D;  1WLF A;  5C18 A;  1E60 A;  3HU3 A;  2ENG A;  3X2L A;  3TM7 B;  1E32 A;  3SUK A;  3O5A A;  1DMS A;  3M3G A;  3IR6 A;  2Y0S A;  4GA6 A;  5DYG A;  1ZC1 A;  1Y1V A;  1BW3 A;  3GTJ A;  1L8F A;  1R9T A;  1TWG A;  4JS7 A;  4JJO A;  2JA5 A;  2JA6 A;  2YU9 A;  1DMR A;  1E61 A;  1Y5I A;  5FTK A;  3GTL A;  4RV0 A;  1TMO A;  1OGY A;  2VPZ A;  1R7R A;  4JCW A;  1CR5 A;  4D7Z B;  5GLY A;  4ZM7 A;  2GAE A;  5H4U A;  2R93 A;  2PMZ A;  5GLF A;  1YLE A;  4JP7 A;  1TWF A;  3X2K A;  3D30 A;  4DMR A;  4GA5 A;  4CRY G;  3QQ8 A;  1AW8 B;  3X2J A;  2JIR A;  5C1B A;  4JP6 A;  2PNW A;  1PYQ A;  2BE5 D;  4ENG A;  1WC2 A;  1Y1W A;  3IR7 A;  1YNJ D;  2V45 A;  1E5V A;  4FFT A;  1H5N A;  5GM9 A;  2KI8 A;  4KDI A;  1Q16 A;  4NOH A;  1G8J A;  1N10 A;  3CF2 A;  4KO8 A;  2V3V A;  5FTM A;  3GTK A;  4KLN A;  2O5J D;  1SFO A;  1SIW A;  5DYI A;  5FTJ A;  3GTO A;  1PQE A;  3HU1 A;  1PPY A;  1PYU B;  2BH0 A;  4AON B;  2VPY A;  3SUM A;  2PJJ A;  1OA9 A;  2G5D A;  3SUJ A;  2WAQ A;  2NVX A;  2PIC A;  1UHD A;  1YNN D;  5GLX A;  2B63 A;  4AZD A;  1TWC A;  3OUG A;  1QDN A;  2E7Z A;  3FKI A;  1VC3 B;  1UHE A;  3HKZ A;  3ML1 A;  5T5M D;  1ZYR D;  2A6H D;  2PI8 A;  1TWH A;  3IR5 A;  3QWZ A;  1HD5 A;  4KDL A;  3QQ7 A;  5EPP A;  3PLX B;  4L48 A;  2KQA A;  3X2P A;  2A69 D;  2VUM A;  1BW4 A;  1Y4Z A;  2CW0 D;  2C45 A;  2R7Z A;  3CQZ A;  2JIQ A;  1TWA A;  4CS0 A;  4AOK B;  1CZ4 A;  3GTP A;  3X2G A; 
#chains in the Genus database with same CATH homology
 1PQH A;  2E2H A;  4KOD A;  4CRZ A;  3GTM A;  4C2M A;  4QIW A;  2NYA A;  1S3S A;  2R92 A;  1KQG A;  2NVY A;  5B6C A;  3GTG A;  2JA7 A;  1K83 A;  1FDI A;  2WB1 A;  1R27 A;  2AE0 X;  5T5I D;  2NAP A;  3HU2 A;  4AYB A;  1IW7 D;  1PT0 A;  1FDO A;  2VPW A;  2VPX A;  1G8K A;  2JIP A;  1WCM A;  2G6G A;  3CZB A;  1I3Q A;  2E2I A;  5FTN A;  1QCS A;  2YUJ A;  1PT1 A;  2JIO A;  4AAY A;  1PQF A;  1E18 A;  1KQF A;  3H0G A;  2IV2 X;  2JIM A;  2PJH B;  2EEO B;  1H0H A;  1CZ5 A;  1AA6 A;  2A6E D;  1I50 A;  5FTL A;  3DMR A;  3GTQ A;  1EU1 A;  3TIW A;  2DMR A;  2A68 D;  3QC8 A;  1SMY D;  1WLF A;  5C18 A;  1E60 A;  3HU3 A;  3TM7 B;  1E32 A;  3O5A A;  1DMS A;  3IR6 A;  4GA6 A;  2Y0S A;  5DYG A;  1ZC1 A;  1Y1V A;  3GTJ A;  1R9T A;  1TWG A;  2JA5 A;  2JA6 A;  2YU9 A;  1DMR A;  1E61 A;  1Y5I A;  5FTK A;  3GTL A;  4RV0 A;  1TMO A;  1OGY A;  2VPZ A;  1R7R A;  4D7Z B;  1CR5 A;  2GAE A;  2R93 A;  2PMZ A;  5GLF A;  1YLE A;  1TWF A;  4DMR A;  4GA5 A;  4CRY G;  3QQ8 A;  1AW8 B;  2JIR A;  5C1B A;  2PNW A;  1PYQ A;  2BE5 D;  1Y1W A;  3IR7 A;  1YNJ D;  2V45 A;  1E5V A;  1H5N A;  2KI8 A;  4KDI A;  1Q16 A;  4NOH A;  1G8J A;  3CF2 A;  4KO8 A;  2V3V A;  5FTM A;  3GTK A;  4KLN A;  2O5J D;  1SFO A;  1SIW A;  5DYI A;  5FTJ A;  3GTO A;  1PQE A;  3HU1 A;  1PPY A;  1PYU B;  4AON B;  2VPY A;  2PJJ A;  2G5D A;  2NVX A;  2WAQ A;  2PIC A;  1UHD A;  1YNN D;  2B63 A;  4AZD A;  1TWC A;  3OUG A;  1QDN A;  2E7Z A;  3FKI A;  1VC3 B;  1UHE A;  3HKZ A;  3ML1 A;  5T5M D;  1ZYR D;  2A6H D;  2PI8 A;  1TWH A;  3IR5 A;  3QWZ A;  4KDL A;  5EPP A;  3QQ7 A;  3PLX B;  2A69 D;  2VUM A;  1Y4Z A;  2CW0 D;  2C45 A;  2R7Z A;  3CQZ A;  2JIQ A;  1TWA A;  4CS0 A;  4AOK B;  1CZ4 A;  3GTP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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