4CS0 | Genus

Total Genus 33

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	33
sequence length	127
structure length	126
Chain Sequence	SMIRTMLQGKLHRVKVTHADLHYEGACAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lyase
source organism	Escherichia coli k-12
publication title	The Structure of the Pand/Panz Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A. pubmed doi rcsb
molecule keywords	ASPARTATE 1-DECARBOXYLASE
total genus	33
structure length	126
sequence length	127
ec nomenclature	ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date	2014-03-02

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02261	Asp_decarbox	Aspartate decarboxylase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.40.40.20	Mainly Beta	Beta Barrel	Barwin-like endoglucanases	Barwin-like endoglucanases	4cs0A00

2VPWA 2V3VA 2R7ZA 1UHDA 2E7ZA 2JA7A 1Y4ZA 1IW7D 1WLFA 1Y1VA 3IR6A 1CZ5A 4CRZA 3GTGA 1G8KA 1TMOA 1QCSA 1DMRA 1TWCA 2KI8A 1PYUB 4KO8A 4CS0A 2R93A 5DYGA 2EEOB 4AYBA 4AZDA 3HKZA 1AA6A 3GTKA 5FTMA 4CRYG 4GA6A 1SIWA 5T5ID 1QDNA 2JIRA 1FDOA 5C1BA 4C2MA 2NYAA 3GTLA 3GTOA 2JA6A 1TWFA 1Q16A 2WB1A 1TWHA 3TIWA 5FTJA 5FTNA 3H0GA 1PQEA 2IV2X 3IR5A 2JIPA 4QIWA 2DMRA 3CQZA 3HU3A 3QQ7A 1FDIA 4AONB 1PQFA 1R27A 4GA5A 1OGYA 2NVYA 2JIOA 3O5AA 5FTKA 4D7ZB 2Y0SA 1PYQA 1VC3B 3GTQA 2NAPA 1E32A 1G8JA 1KQGA 3ML1A 4KDLA 4AAYA 4KDIA 5DYIA 1H0HA 2C45A 1PT1A 3HU2A 3QQ8A 1UHEA 1E5VA 5T5MD 1PT0A 5EPPA 2PMZA 3GTMA 1KQFA 1SFOA 3PLXB 1H5NA 1CZ4A 2NVXA 2JA5A 2B63A 1I50A 2E2IA 3TM7B 2V45A 2E2HA 3DMRA 2R92A 1S3SA 4AOKB 1I3QA 3HU1A 5B6CA 2JIQA 1K83A 2VPXA 1TWGA 4RV0A 4DMRA 1E61A 3GTJA 1PPYA 2VUMA 5GLFA 3GTPA 1Y1WA 1Y5IA 2VPZA 2PJHB 2VPYA 1PQHA 1YLEA 4KLNA 1DMSA 5FTLA 1E18A 3CF2A 1E60A 3QC8A 1TWAA 3FKIA 3IR7A 4KODA 2WAQA 1EU1A 3OUGA 3QWZA 1R9TA 2JIMA 1AW8B 1CR5A 1R7RA 1WCMA 2YU9A 5C18A
chains in the Genus database with same CATH superfamily

2VPWA 1BW3A 2V3VA 2R7ZA 4ZM7A 1UHDA 2E7ZA 2JA7A 2KQAA 1Y4ZA 1IW7D 1WLFA 1Y1VA 3IR6A 1CZ5A 4CRZA 1L8FA 4L48A 3GTGA 1SMYD 1G8KA 1TMOA 1QCSA 1DMRA 1TWCA 1YNND 2A6ED 2KI8A 1PYUB 4KO8A 4CS0A 2R93A 5DYGA 5GLYA 2EEOB 4NOHA 4AYBA 4AZDA 3HKZA 1AA6A 3GTKA 2ENGA 5FTMA 5H4UA 4CRYG 2A6HD 1SIWA 4GA6A 5T5ID 2PNWA 1QDNA 2JIRA 1FDOA 4AVRA 4C2MA 5C1BA 2AE0X 2NYAA 3GTLA 3GTOA 2JA6A 1TWFA 4JJOA 2BE5D 1Q16A 2WB1A 1TWHA 3TIWA 5FTJA 5FTNA 2HCZX 3H0GA 1PQEA 2IV2X 2O5JD 3IR5A 3X2IA 2JIPA 4QIWA 2G5DA 3SULA 2DMRA 3CQZA 3HU3A 3QQ7A 1FDIA 4AONB 1PQFA 1R27A 4GA5A 2GAEA 1OGYA 2NVYA 2A69D 2JIOA 3O5AA 5FTKA 4D7ZB 2Y0SA 3X2NA 1PYQA 1VC3B 3GTQA 2PJJA 2NAPA 4JS7A 1E32A 3X2PA 1G8JA 3X2OA 1KQGA 3ML1A 4KDLA 5GLXA 3X2JA 2PICA 3X2KA 3X2HA 4AAYA 4KDIA 5DYIA 4FG4A 1H0HA 2C45A 1PT1A 3HU2A 3QQ8A 1UHEA 3X2MA 1OA9A 1E5VA 4JCWA 5T5MD 1PT0A 4FG2A 2PMZA 5EPPA 3GTMA 1KQFA 3CZBA 2BH0A 1SFOA 3PLXB 1H5NA 1CZ4A 3X2LA 1OA7A 1WC2A 2NVXA 2JA5A 2B63A 4ENGA 1I50A 2E2IA 3TM7B 2V45A 2E2HA 3DMRA 2R92A 1ZYRD 1S3SA 3X2GA 4AOKB 1I3QA 3HU1A 5B6CA 4JP7A 1BW4A 2JIQA 1K83A 2VPXA 1TWGA 2G6GA 1N10A 4RV0A 4DMRA 1E61A 3GTJA 1HD5A 1PPYA 2VUMA 5GM9A 2CW0D 5GLFA 3D30A 3GTPA 1Y1WA 1Y5IA 3M3GA 2VPZA 2PJHB 2VPYA 3ENGA 4FFTA 2YUJA 1PQHA 3SUKA 1YLEA 3SUJA 2PI8A 4KLNA 1DMSA 5FTLA 4FERA 1E18A 3CF2A 3SUMA 1E60A 3QC8A 1TWAA 3FKIA 1ZC1A 3IR7A 4KODA 2WAQA 1EU1A 3OUGA 1YNJD 3QWZA 1R9TA 2JIMA 1AW8B 2A68D 1CR5A 1R7RA 1WCMA 2YU9A 4JP6A 5C18A
chains in the Genus database with same CATH topology

2VPWA 2V3VA 2R7ZA 1UHDA 2E7ZA 2JA7A 1Y4ZA 1IW7D 1WLFA 1Y1VA 3IR6A 1CZ5A 4CRZA 3GTGA 1SMYD 1G8KA 1TMOA 1QCSA 1DMRA 1TWCA 1YNND 2A6ED 2KI8A 1PYUB 4KO8A 4CS0A 2R93A 5DYGA 2EEOB 4NOHA 4AYBA 4AZDA 3HKZA 1AA6A 3GTKA 5FTMA 4CRYG 2A6HD 1SIWA 4GA6A 5T5ID 2PNWA 1QDNA 2JIRA 1FDOA 5C1BA 4C2MA 2NYAA 2AE0X 3GTLA 3GTOA 2JA6A 1TWFA 2BE5D 1Q16A 2WB1A 1TWHA 3TIWA 5FTJA 5FTNA 3H0GA 1PQEA 2IV2X 2O5JD 3IR5A 2JIPA 4QIWA 2G5DA 2DMRA 3CQZA 3HU3A 3QQ7A 1FDIA 4AONB 1PQFA 1R27A 4GA5A 2GAEA 1OGYA 2NVYA 2A69D 2JIOA 3O5AA 5FTKA 4D7ZB 2Y0SA 1PYQA 1VC3B 3GTQA 2PJJA 2NAPA 1E32A 1G8JA 1KQGA 3ML1A 4KDLA 4AAYA 2PICA 4KDIA 5DYIA 1H0HA 2C45A 1PT1A 3HU2A 3QQ8A 1UHEA 1E5VA 5T5MD 1PT0A 5EPPA 2PMZA 3GTMA 1KQFA 3CZBA 1SFOA 3PLXB 1H5NA 1CZ4A 2NVXA 2JA5A 2B63A 1I50A 2E2IA 3TM7B 2V45A 2E2HA 3DMRA 2R92A 1ZYRD 1S3SA 4AOKB 1I3QA 3HU1A 5B6CA 2JIQA 1K83A 2VPXA 1TWGA 2G6GA 4RV0A 4DMRA 1E61A 3GTJA 1PPYA 2VUMA 2CW0D 5GLFA 3GTPA 1Y1WA 1Y5IA 2VPZA 2PJHB 2VPYA 2YUJA 1PQHA 1YLEA 2PI8A 4KLNA 1DMSA 5FTLA 1E18A 3CF2A 1E60A 3QC8A 1TWAA 3FKIA 1ZC1A 3IR7A 4KODA 2WAQA 1EU1A 3OUGA 1YNJD 3QWZA 1R9TA 2JIMA 1AW8B 2A68D 1CR5A 1R7RA 1WCMA 2YU9A 5C18A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2VPW A;  2V3V A;  2R7Z A;  1UHD A;  2E7Z A;  2JA7 A;  1Y4Z A;  1IW7 D;  1WLF A;  1Y1V A;  3IR6 A;  1CZ5 A;  4CRZ A;  3GTG A;  1G8K A;  1TMO A;  1QCS A;  1DMR A;  1TWC A;  2KI8 A;  1PYU B;  4KO8 A;  4CS0 A;  2R93 A;  5DYG A;  2EEO B;  4AYB A;  4AZD A;  3HKZ A;  1AA6 A;  3GTK A;  5FTM A;  4CRY G;  4GA6 A;  1SIW A;  5T5I D;  1QDN A;  2JIR A;  1FDO A;  5C1B A;  4C2M A;  2NYA A;  3GTL A;  3GTO A;  2JA6 A;  1TWF A;  1Q16 A;  2WB1 A;  1TWH A;  3TIW A;  5FTJ A;  5FTN A;  3H0G A;  1PQE A;  2IV2 X;  3IR5 A;  2JIP A;  4QIW A;  2DMR A;  3CQZ A;  3HU3 A;  3QQ7 A;  1FDI A;  4AON B;  1PQF A;  1R27 A;  4GA5 A;  1OGY A;  2NVY A;  2JIO A;  3O5A A;  5FTK A;  4D7Z B;  2Y0S A;  1PYQ A;  1VC3 B;  3GTQ A;  2NAP A;  1E32 A;  1G8J A;  1KQG A;  3ML1 A;  4KDL A;  4AAY A;  4KDI A;  5DYI A;  1H0H A;  2C45 A;  1PT1 A;  3HU2 A;  3QQ8 A;  1UHE A;  1E5V A;  5T5M D;  1PT0 A;  5EPP A;  2PMZ A;  3GTM A;  1KQF A;  1SFO A;  3PLX B;  1H5N A;  1CZ4 A;  2NVX A;  2JA5 A;  2B63 A;  1I50 A;  2E2I A;  3TM7 B;  2V45 A;  2E2H A;  3DMR A;  2R92 A;  1S3S A;  4AOK B;  1I3Q A;  3HU1 A;  5B6C A;  2JIQ A;  1K83 A;  2VPX A;  1TWG A;  4RV0 A;  4DMR A;  1E61 A;  3GTJ A;  1PPY A;  2VUM A;  5GLF A;  3GTP A;  1Y1W A;  1Y5I A;  2VPZ A;  2PJH B;  2VPY A;  1PQH A;  1YLE A;  4KLN A;  1DMS A;  5FTL A;  1E18 A;  3CF2 A;  1E60 A;  3QC8 A;  1TWA A;  3FKI A;  3IR7 A;  4KOD A;  2WAQ A;  1EU1 A;  3OUG A;  3QWZ A;  1R9T A;  2JIM A;  1AW8 B;  1CR5 A;  1R7R A;  1WCM A;  2YU9 A;  5C18 A; 
#chains in the Genus database with same CATH topology
 2VPW A;  1BW3 A;  2V3V A;  2R7Z A;  4ZM7 A;  1UHD A;  2E7Z A;  2JA7 A;  2KQA A;  1Y4Z A;  1IW7 D;  1WLF A;  1Y1V A;  3IR6 A;  1CZ5 A;  4CRZ A;  1L8F A;  4L48 A;  3GTG A;  1SMY D;  1G8K A;  1TMO A;  1QCS A;  1DMR A;  1TWC A;  1YNN D;  2A6E D;  2KI8 A;  1PYU B;  4KO8 A;  4CS0 A;  2R93 A;  5DYG A;  5GLY A;  2EEO B;  4NOH A;  4AYB A;  4AZD A;  3HKZ A;  1AA6 A;  3GTK A;  2ENG A;  5FTM A;  5H4U A;  4CRY G;  2A6H D;  1SIW A;  4GA6 A;  5T5I D;  2PNW A;  1QDN A;  2JIR A;  1FDO A;  4AVR A;  4C2M A;  5C1B A;  2AE0 X;  2NYA A;  3GTL A;  3GTO A;  2JA6 A;  1TWF A;  4JJO A;  2BE5 D;  1Q16 A;  2WB1 A;  1TWH A;  3TIW A;  5FTJ A;  5FTN A;  2HCZ X;  3H0G A;  1PQE A;  2IV2 X;  2O5J D;  3IR5 A;  3X2I A;  2JIP A;  4QIW A;  2G5D A;  3SUL A;  2DMR A;  3CQZ A;  3HU3 A;  3QQ7 A;  1FDI A;  4AON B;  1PQF A;  1R27 A;  4GA5 A;  2GAE A;  1OGY A;  2NVY A;  2A69 D;  2JIO A;  3O5A A;  5FTK A;  4D7Z B;  2Y0S A;  3X2N A;  1PYQ A;  1VC3 B;  3GTQ A;  2PJJ A;  2NAP A;  4JS7 A;  1E32 A;  3X2P A;  1G8J A;  3X2O A;  1KQG A;  3ML1 A;  4KDL A;  5GLX A;  3X2J A;  2PIC A;  3X2K A;  3X2H A;  4AAY A;  4KDI A;  5DYI A;  4FG4 A;  1H0H A;  2C45 A;  1PT1 A;  3HU2 A;  3QQ8 A;  1UHE A;  3X2M A;  1OA9 A;  1E5V A;  4JCW A;  5T5M D;  1PT0 A;  4FG2 A;  2PMZ A;  5EPP A;  3GTM A;  1KQF A;  3CZB A;  2BH0 A;  1SFO A;  3PLX B;  1H5N A;  1CZ4 A;  3X2L A;  1OA7 A;  1WC2 A;  2NVX A;  2JA5 A;  2B63 A;  4ENG A;  1I50 A;  2E2I A;  3TM7 B;  2V45 A;  2E2H A;  3DMR A;  2R92 A;  1ZYR D;  1S3S A;  3X2G A;  4AOK B;  1I3Q A;  3HU1 A;  5B6C A;  4JP7 A;  1BW4 A;  2JIQ A;  1K83 A;  2VPX A;  1TWG A;  2G6G A;  1N10 A;  4RV0 A;  4DMR A;  1E61 A;  3GTJ A;  1HD5 A;  1PPY A;  2VUM A;  5GM9 A;  2CW0 D;  5GLF A;  3D30 A;  3GTP A;  1Y1W A;  1Y5I A;  3M3G A;  2VPZ A;  2PJH B;  2VPY A;  3ENG A;  4FFT A;  2YUJ A;  1PQH A;  3SUK A;  1YLE A;  3SUJ A;  2PI8 A;  4KLN A;  1DMS A;  5FTL A;  4FER A;  1E18 A;  3CF2 A;  3SUM A;  1E60 A;  3QC8 A;  1TWA A;  3FKI A;  1ZC1 A;  3IR7 A;  4KOD A;  2WAQ A;  1EU1 A;  3OUG A;  1YNJ D;  3QWZ A;  1R9T A;  2JIM A;  1AW8 B;  2A68 D;  1CR5 A;  1R7R A;  1WCM A;  2YU9 A;  4JP6 A;  5C18 A; 
#chains in the Genus database with same CATH homology
 2VPW A;  2V3V A;  2R7Z A;  1UHD A;  2E7Z A;  2JA7 A;  1Y4Z A;  1IW7 D;  1WLF A;  1Y1V A;  3IR6 A;  1CZ5 A;  4CRZ A;  3GTG A;  1SMY D;  1G8K A;  1TMO A;  1QCS A;  1DMR A;  1TWC A;  1YNN D;  2A6E D;  2KI8 A;  1PYU B;  4KO8 A;  4CS0 A;  2R93 A;  5DYG A;  2EEO B;  4NOH A;  4AYB A;  4AZD A;  3HKZ A;  1AA6 A;  3GTK A;  5FTM A;  4CRY G;  2A6H D;  1SIW A;  4GA6 A;  5T5I D;  2PNW A;  1QDN A;  2JIR A;  1FDO A;  5C1B A;  4C2M A;  2NYA A;  2AE0 X;  3GTL A;  3GTO A;  2JA6 A;  1TWF A;  2BE5 D;  1Q16 A;  2WB1 A;  1TWH A;  3TIW A;  5FTJ A;  5FTN A;  3H0G A;  1PQE A;  2IV2 X;  2O5J D;  3IR5 A;  2JIP A;  4QIW A;  2G5D A;  2DMR A;  3CQZ A;  3HU3 A;  3QQ7 A;  1FDI A;  4AON B;  1PQF A;  1R27 A;  4GA5 A;  2GAE A;  1OGY A;  2NVY A;  2A69 D;  2JIO A;  3O5A A;  5FTK A;  4D7Z B;  2Y0S A;  1PYQ A;  1VC3 B;  3GTQ A;  2PJJ A;  2NAP A;  1E32 A;  1G8J A;  1KQG A;  3ML1 A;  4KDL A;  4AAY A;  2PIC A;  4KDI A;  5DYI A;  1H0H A;  2C45 A;  1PT1 A;  3HU2 A;  3QQ8 A;  1UHE A;  1E5V A;  5T5M D;  1PT0 A;  5EPP A;  2PMZ A;  3GTM A;  1KQF A;  3CZB A;  1SFO A;  3PLX B;  1H5N A;  1CZ4 A;  2NVX A;  2JA5 A;  2B63 A;  1I50 A;  2E2I A;  3TM7 B;  2V45 A;  2E2H A;  3DMR A;  2R92 A;  1ZYR D;  1S3S A;  4AOK B;  1I3Q A;  3HU1 A;  5B6C A;  2JIQ A;  1K83 A;  2VPX A;  1TWG A;  2G6G A;  4RV0 A;  4DMR A;  1E61 A;  3GTJ A;  1PPY A;  2VUM A;  2CW0 D;  5GLF A;  3GTP A;  1Y1W A;  1Y5I A;  2VPZ A;  2PJH B;  2VPY A;  2YUJ A;  1PQH A;  1YLE A;  2PI8 A;  4KLN A;  1DMS A;  5FTL A;  1E18 A;  3CF2 A;  1E60 A;  3QC8 A;  1TWA A;  3FKI A;  1ZC1 A;  3IR7 A;  4KOD A;  2WAQ A;  1EU1 A;  3OUG A;  1YNJ D;  3QWZ A;  1R9T A;  2JIM A;  1AW8 B;  2A68 D;  1CR5 A;  1R7R A;  1WCM A;  2YU9 A;  5C18 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4CS0A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations