4CS0A

Direct visualisation of strain-induced protein post-translational modification
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
127
structure length
126
Chain Sequence
SMIRTMLQGKLHRVKVTHADLHYEGACAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the Pand/Panz Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A.
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli k-12
molecule keywords ASPARTATE 1-DECARBOXYLASE
total genus 33
structure length 126
sequence length 127
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2014-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4cs0A00
1E60A 2C45A 4CS0A 1TWCA 3PLXB 1Q16A 2VPXA 1PYUB 2V45A 1KQGA 1G8JA 1CZ4A 1WCMA 5T5MD 2R93A 1TWHA 1AW8B 3CQZA 1R27A 3TIWA 1PPYA 1E61A 3HU1A 3QC8A 4KODA 2JA7A 2JIRA 1SFOA 2WAQA 2PMZA 2JIOA 3TM7B 1E18A 5C1BA 1KQFA 3GTMA 1E5VA 1YLEA 3QQ7A 4C2MA 2WB1A 1TWFA 1H5NA 1WLFA 4AOKB 5GLFA 3GTQA 3QQ8A 4KDIA 5T5ID 1PT1A 1OGYA 3IR6A 1FDOA 2NYAA 5B6CA 2JIMA 1I3QA 3GTJA 3HKZA 1TWAA 2VPWA 3OUGA 2PJHB 3FKIA 5FTLA 2NVYA 5FTMA 1DMSA 2YU9A 3GTOA 4QIWA 1Y5IA 4GA6A 3GTGA 1Y1WA 1QCSA 4DMRA 3CF2A 1EU1A 1R7RA 1S3SA 2VPYA 3H0GA 1E32A 2JA6A 3DMRA 3QWZA 3IR5A 1Y4ZA 1PT0A 1IW7D 2V3VA 1PQHA 2B63A 5FTJA 2R7ZA 2KI8A 3HU2A 1FDIA 3IR7A 1Y1VA 2NVXA 4GA5A 2DMRA 2JIPA 2JIQA 1CR5A 4RV0A 3HU3A 2Y0SA 2NAPA 1UHDA 1AA6A 1QDNA 4CRYG 1PQEA 2E2HA 2EEOB 2VPZA 5EPPA 1PQFA 2VUMA 1VC3B 1SIWA 3O5AA 2E2IA 5DYIA 4KLNA 2IV2X 1TWGA 4AONB 1K83A 4KO8A 2R92A 1DMRA 2JA5A 4AYBA 1PYQA 3GTPA 1UHEA 1TMOA 1CZ5A 3GTKA 5DYGA 1I50A 4D7ZB 1R9TA 5FTNA 5C18A 4AAYA 5FTKA 1G8KA 2E7ZA 4AZDA 3ML1A 1H0HA 4CRZA 3GTLA 4KDLA
chains in the Genus database with same CATH superfamily
1E60A 2C45A 4CS0A 1TWCA 3PLXB 1Q16A 2VPXA 1PYUB 4AVRA 2V45A 3X2PA 1KQGA 2BH0A 1G8JA 1CZ4A 1WCMA 5T5MD 2R93A 1TWHA 1AW8B 1YNJD 3CQZA 1R27A 3CZBA 3TIWA 1PPYA 1E61A 3HU1A 3QC8A 4KODA 1HD5A 1ZC1A 1YNND 4JCWA 2JA7A 2JIRA 4NOHA 1SFOA 2HCZX 2WAQA 2PMZA 2JIOA 1SMYD 1E18A 2A6ED 4FG4A 3TM7B 5C1BA 1KQFA 3GTMA 1E5VA 1YLEA 3QQ7A 3X2OA 4FERA 4C2MA 2O5JD 2WB1A 1TWFA 2A6HD 2GAEA 3M3GA 1H5NA 1WLFA 4AOKB 5GLFA 3GTQA 3QQ8A 2PJJA 4KDIA 5T5ID 5GM9A 3X2IA 1PT1A 1OA7A 1N10A 1OGYA 3IR6A 1FDOA 2NYAA 5GLXA 3X2LA 5H4UA 5B6CA 2JIMA 1I3QA 3GTJA 3HKZA 1TWAA 2VPWA 4JJOA 3X2KA 3OUGA 2PJHB 3D30A 3FKIA 5FTLA 5GLYA 2NVYA 5FTMA 1DMSA 2YU9A 3SUJA 3GTOA 4QIWA 3ENGA 1Y5IA 4JS7A 4GA6A 3GTGA 2PICA 1Y1WA 1QCSA 4DMRA 3CF2A 1EU1A 2A69D 4L48A 3X2NA 1R7RA 2G5DA 3SULA 1S3SA 2VPYA 3H0GA 2ENGA 1E32A 2PI8A 3DMRA 3QWZA 2JA6A 3IR5A 1Y4ZA 1PT0A 1IW7D 4FFTA 2V3VA 1PQHA 2B63A 5FTJA 2R7ZA 2CW0D 4JP6A 2KI8A 3HU2A 1FDIA 3IR7A 2KQAA 1Y1VA 1WC2A 2PNWA 2NVXA 4GA5A 2DMRA 2JIPA 2JIQA 2G6GA 2A68D 2YUJA 1CR5A 4RV0A 3HU3A 2Y0SA 2NAPA 1UHDA 1AA6A 1QDNA 4CRYG 1OA9A 1L8FA 1PQEA 4ZM7A 2E2HA 2EEOB 2VPZA 5EPPA 1PQFA 2VUMA 1VC3B 4JP7A 1SIWA 3O5AA 4FG2A 2E2IA 1BW4A 4ENGA 5DYIA 4KLNA 2IV2X 1TWGA 4AONB 1K83A 4KO8A 2R92A 1DMRA 2JA5A 4AYBA 1PYQA 2BE5D 3GTPA 3SUMA 1ZYRD 1UHEA 1TMOA 1BW3A 1CZ5A 3X2HA 3GTKA 5DYGA 1I50A 4D7ZB 2AE0X 1R9TA 5FTNA 5C18A 4AAYA 5FTKA 1G8KA 2E7ZA 3SUKA 4AZDA 3ML1A 1H0HA 3X2JA 4CRZA 3GTLA 4KDLA 3X2GA 3X2MA
chains in the Genus database with same CATH topology
1E60A 2C45A 4CS0A 1TWCA 3PLXB 1Q16A 2VPXA 1PYUB 2V45A 1KQGA 1G8JA 1CZ4A 1WCMA 5T5MD 2R93A 1TWHA 1AW8B 1YNJD 3CQZA 1R27A 3CZBA 3TIWA 1PPYA 1E61A 3HU1A 3QC8A 4KODA 1ZC1A 1YNND 2JA7A 2JIRA 4NOHA 1SFOA 2WAQA 2PMZA 2JIOA 1SMYD 1E18A 2A6ED 3TM7B 5C1BA 1KQFA 3GTMA 1E5VA 1YLEA 3QQ7A 4C2MA 2O5JD 2WB1A 1TWFA 2A6HD 2GAEA 1H5NA 1WLFA 4AOKB 5GLFA 3GTQA 3QQ8A 2PJJA 4KDIA 5T5ID 1PT1A 1OGYA 3IR6A 1FDOA 2NYAA 5B6CA 2JIMA 1I3QA 3GTJA 3HKZA 1TWAA 2VPWA 3OUGA 2PJHB 3FKIA 5FTLA 2NVYA 5FTMA 1DMSA 2YU9A 3GTOA 4QIWA 1Y5IA 4GA6A 3GTGA 2PICA 1Y1WA 1QCSA 4DMRA 3CF2A 1EU1A 2A69D 1R7RA 2G5DA 1S3SA 2VPYA 3H0GA 1E32A 2PI8A 3DMRA 3QWZA 2JA6A 3IR5A 1Y4ZA 1PT0A 1IW7D 2V3VA 1PQHA 2B63A 5FTJA 2R7ZA 2CW0D 2KI8A 3HU2A 1FDIA 3IR7A 1Y1VA 2PNWA 2NVXA 4GA5A 2DMRA 2JIPA 2JIQA 2G6GA 2A68D 2YUJA 1CR5A 4RV0A 3HU3A 2Y0SA 2NAPA 1UHDA 1AA6A 1QDNA 4CRYG 1PQEA 2E2HA 2EEOB 2VPZA 5EPPA 1PQFA 2VUMA 1VC3B 1SIWA 3O5AA 2E2IA 5DYIA 4KLNA 2IV2X 1TWGA 4AONB 1K83A 4KO8A 2R92A 1DMRA 2JA5A 4AYBA 1PYQA 2BE5D 3GTPA 1ZYRD 1UHEA 1TMOA 1CZ5A 3GTKA 5DYGA 1I50A 4D7ZB 2AE0X 1R9TA 5FTNA 5C18A 4AAYA 5FTKA 1G8KA 2E7ZA 4AZDA 3ML1A 1H0HA 4CRZA 3GTLA 4KDLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E60 A;  2C45 A;  4CS0 A;  1TWC A;  3PLX B;  1Q16 A;  2VPX A;  1PYU B;  2V45 A;  1KQG A;  1G8J A;  1CZ4 A;  1WCM A;  5T5M D;  2R93 A;  1TWH A;  1AW8 B;  3CQZ A;  1R27 A;  3TIW A;  1PPY A;  1E61 A;  3HU1 A;  3QC8 A;  4KOD A;  2JA7 A;  2JIR A;  1SFO A;  2WAQ A;  2PMZ A;  2JIO A;  3TM7 B;  1E18 A;  5C1B A;  1KQF A;  3GTM A;  1E5V A;  1YLE A;  3QQ7 A;  4C2M A;  2WB1 A;  1TWF A;  1H5N A;  1WLF A;  4AOK B;  5GLF A;  3GTQ A;  3QQ8 A;  4KDI A;  5T5I D;  1PT1 A;  1OGY A;  3IR6 A;  1FDO A;  2NYA A;  5B6C A;  2JIM A;  1I3Q A;  3GTJ A;  3HKZ A;  1TWA A;  2VPW A;  3OUG A;  2PJH B;  3FKI A;  5FTL A;  2NVY A;  5FTM A;  1DMS A;  2YU9 A;  3GTO A;  4QIW A;  1Y5I A;  4GA6 A;  3GTG A;  1Y1W A;  1QCS A;  4DMR A;  3CF2 A;  1EU1 A;  1R7R A;  1S3S A;  2VPY A;  3H0G A;  1E32 A;  2JA6 A;  3DMR A;  3QWZ A;  3IR5 A;  1Y4Z A;  1PT0 A;  1IW7 D;  2V3V A;  1PQH A;  2B63 A;  5FTJ A;  2R7Z A;  2KI8 A;  3HU2 A;  1FDI A;  3IR7 A;  1Y1V A;  2NVX A;  4GA5 A;  2DMR A;  2JIP A;  2JIQ A;  1CR5 A;  4RV0 A;  3HU3 A;  2Y0S A;  2NAP A;  1UHD A;  1AA6 A;  1QDN A;  4CRY G;  1PQE A;  2E2H A;  2EEO B;  2VPZ A;  5EPP A;  1PQF A;  2VUM A;  1VC3 B;  1SIW A;  3O5A A;  2E2I A;  5DYI A;  4KLN A;  2IV2 X;  1TWG A;  4AON B;  1K83 A;  4KO8 A;  2R92 A;  1DMR A;  2JA5 A;  4AYB A;  1PYQ A;  3GTP A;  1UHE A;  1TMO A;  1CZ5 A;  3GTK A;  5DYG A;  1I50 A;  4D7Z B;  1R9T A;  5FTN A;  5C18 A;  4AAY A;  5FTK A;  1G8K A;  2E7Z A;  4AZD A;  3ML1 A;  1H0H A;  4CRZ A;  3GTL A;  4KDL A; 
#chains in the Genus database with same CATH topology
 1E60 A;  2C45 A;  4CS0 A;  1TWC A;  3PLX B;  1Q16 A;  2VPX A;  1PYU B;  4AVR A;  2V45 A;  3X2P A;  1KQG A;  2BH0 A;  1G8J A;  1CZ4 A;  1WCM A;  5T5M D;  2R93 A;  1TWH A;  1AW8 B;  1YNJ D;  3CQZ A;  1R27 A;  3CZB A;  3TIW A;  1PPY A;  1E61 A;  3HU1 A;  3QC8 A;  4KOD A;  1HD5 A;  1ZC1 A;  1YNN D;  4JCW A;  2JA7 A;  2JIR A;  4NOH A;  1SFO A;  2HCZ X;  2WAQ A;  2PMZ A;  2JIO A;  1SMY D;  1E18 A;  2A6E D;  4FG4 A;  3TM7 B;  5C1B A;  1KQF A;  3GTM A;  1E5V A;  1YLE A;  3QQ7 A;  3X2O A;  4FER A;  4C2M A;  2O5J D;  2WB1 A;  1TWF A;  2A6H D;  2GAE A;  3M3G A;  1H5N A;  1WLF A;  4AOK B;  5GLF A;  3GTQ A;  3QQ8 A;  2PJJ A;  4KDI A;  5T5I D;  5GM9 A;  3X2I A;  1PT1 A;  1OA7 A;  1N10 A;  1OGY A;  3IR6 A;  1FDO A;  2NYA A;  5GLX A;  3X2L A;  5H4U A;  5B6C A;  2JIM A;  1I3Q A;  3GTJ A;  3HKZ A;  1TWA A;  2VPW A;  4JJO A;  3X2K A;  3OUG A;  2PJH B;  3D30 A;  3FKI A;  5FTL A;  5GLY A;  2NVY A;  5FTM A;  1DMS A;  2YU9 A;  3SUJ A;  3GTO A;  4QIW A;  3ENG A;  1Y5I A;  4JS7 A;  4GA6 A;  3GTG A;  2PIC A;  1Y1W A;  1QCS A;  4DMR A;  3CF2 A;  1EU1 A;  2A69 D;  4L48 A;  3X2N A;  1R7R A;  2G5D A;  3SUL A;  1S3S A;  2VPY A;  3H0G A;  2ENG A;  1E32 A;  2PI8 A;  3DMR A;  3QWZ A;  2JA6 A;  3IR5 A;  1Y4Z A;  1PT0 A;  1IW7 D;  4FFT A;  2V3V A;  1PQH A;  2B63 A;  5FTJ A;  2R7Z A;  2CW0 D;  4JP6 A;  2KI8 A;  3HU2 A;  1FDI A;  3IR7 A;  2KQA A;  1Y1V A;  1WC2 A;  2PNW A;  2NVX A;  4GA5 A;  2DMR A;  2JIP A;  2JIQ A;  2G6G A;  2A68 D;  2YUJ A;  1CR5 A;  4RV0 A;  3HU3 A;  2Y0S A;  2NAP A;  1UHD A;  1AA6 A;  1QDN A;  4CRY G;  1OA9 A;  1L8F A;  1PQE A;  4ZM7 A;  2E2H A;  2EEO B;  2VPZ A;  5EPP A;  1PQF A;  2VUM A;  1VC3 B;  4JP7 A;  1SIW A;  3O5A A;  4FG2 A;  2E2I A;  1BW4 A;  4ENG A;  5DYI A;  4KLN A;  2IV2 X;  1TWG A;  4AON B;  1K83 A;  4KO8 A;  2R92 A;  1DMR A;  2JA5 A;  4AYB A;  1PYQ A;  2BE5 D;  3GTP A;  3SUM A;  1ZYR D;  1UHE A;  1TMO A;  1BW3 A;  1CZ5 A;  3X2H A;  3GTK A;  5DYG A;  1I50 A;  4D7Z B;  2AE0 X;  1R9T A;  5FTN A;  5C18 A;  4AAY A;  5FTK A;  1G8K A;  2E7Z A;  3SUK A;  4AZD A;  3ML1 A;  1H0H A;  3X2J A;  4CRZ A;  3GTL A;  4KDL A;  3X2G A;  3X2M A; 
#chains in the Genus database with same CATH homology
 1E60 A;  2C45 A;  4CS0 A;  1TWC A;  3PLX B;  1Q16 A;  2VPX A;  1PYU B;  2V45 A;  1KQG A;  1G8J A;  1CZ4 A;  1WCM A;  5T5M D;  2R93 A;  1TWH A;  1AW8 B;  1YNJ D;  3CQZ A;  1R27 A;  3CZB A;  3TIW A;  1PPY A;  1E61 A;  3HU1 A;  3QC8 A;  4KOD A;  1ZC1 A;  1YNN D;  2JA7 A;  2JIR A;  4NOH A;  1SFO A;  2WAQ A;  2PMZ A;  2JIO A;  1SMY D;  1E18 A;  2A6E D;  3TM7 B;  5C1B A;  1KQF A;  3GTM A;  1E5V A;  1YLE A;  3QQ7 A;  4C2M A;  2O5J D;  2WB1 A;  1TWF A;  2A6H D;  2GAE A;  1H5N A;  1WLF A;  4AOK B;  5GLF A;  3GTQ A;  3QQ8 A;  2PJJ A;  4KDI A;  5T5I D;  1PT1 A;  1OGY A;  3IR6 A;  1FDO A;  2NYA A;  5B6C A;  2JIM A;  1I3Q A;  3GTJ A;  3HKZ A;  1TWA A;  2VPW A;  3OUG A;  2PJH B;  3FKI A;  5FTL A;  2NVY A;  5FTM A;  1DMS A;  2YU9 A;  3GTO A;  4QIW A;  1Y5I A;  4GA6 A;  3GTG A;  2PIC A;  1Y1W A;  1QCS A;  4DMR A;  3CF2 A;  1EU1 A;  2A69 D;  1R7R A;  2G5D A;  1S3S A;  2VPY A;  3H0G A;  1E32 A;  2PI8 A;  3DMR A;  3QWZ A;  2JA6 A;  3IR5 A;  1Y4Z A;  1PT0 A;  1IW7 D;  2V3V A;  1PQH A;  2B63 A;  5FTJ A;  2R7Z A;  2CW0 D;  2KI8 A;  3HU2 A;  1FDI A;  3IR7 A;  1Y1V A;  2PNW A;  2NVX A;  4GA5 A;  2DMR A;  2JIP A;  2JIQ A;  2G6G A;  2A68 D;  2YUJ A;  1CR5 A;  4RV0 A;  3HU3 A;  2Y0S A;  2NAP A;  1UHD A;  1AA6 A;  1QDN A;  4CRY G;  1PQE A;  2E2H A;  2EEO B;  2VPZ A;  5EPP A;  1PQF A;  2VUM A;  1VC3 B;  1SIW A;  3O5A A;  2E2I A;  5DYI A;  4KLN A;  2IV2 X;  1TWG A;  4AON B;  1K83 A;  4KO8 A;  2R92 A;  1DMR A;  2JA5 A;  4AYB A;  1PYQ A;  2BE5 D;  3GTP A;  1ZYR D;  1UHE A;  1TMO A;  1CZ5 A;  3GTK A;  5DYG A;  1I50 A;  4D7Z B;  2AE0 X;  1R9T A;  5FTN A;  5C18 A;  4AAY A;  5FTK A;  1G8K A;  2E7Z A;  4AZD A;  3ML1 A;  1H0H A;  4CRZ A;  3GTL A;  4KDL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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