4NA9L

Factor viia in complex with the inhibitor 3'-amino-5'-[(2s,4r)-6-carbamimidoyl-4-phenyl-1,2,3,4-tetrahydroquinolin-2-yl]biphenyl-2-carboxylic acid
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
55
structure length
55
Chain Sequence
ICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Tetrahydroquinoline Derivatives as Potent and Selective Factor XIa Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Coagulation factor VII heavy chain
total genus 12
structure length 55
sequence length 55
ec nomenclature ec 3.4.21.21: Coagulation factor VIIa.
pdb deposition date 2013-10-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 4na9L00
1CVUA 4X8VL 1GK5A 3LTFB 1HAFA 1FSBA 5JB9E 1YUFA 4RRXA 1F0SB 2VH6B 3CS7L 1ATDA 2UWOB 2MHPA 4BXSA 4X8TL 4Y7AB 2P3UA 4AQTA 1TPGA 4BDWA 1G2LB 1CVWL 5I46L 1LPZA 1SZBA 2Y82B 2EI6B 3LC3B 4Y76B 4BTIA 2Q1JB 3KQDL 2FZZL 2OYEP 1WU1B 1DX5I 1HZ8A 3ENSA 2WPLE 1PTHA 1DVAL 1PXXA 1MQ6L 3HPTA 3KK6A 5JBAE 1NFUB 2KB9A 1PGEA 1HAEA 1OB1C 3NJPC 3KL6B 3ASIA 2WPIE 1HT5A 2BZ6L 2P28B 2K2SB 3KRKA 2VWNL 2XC4L 4G1MB 5JB8E 2WPJE 1YUKB 4ZXYL 3R05A 2RNLA 2Y5GL 4ISIL 1G1SA 3BPSE 5E8DA 2EI8B 1EQGA 1N7DA 1YO8A 2BQ7A 1FJSL 4MMXB 4CSYA 2J2UB 3OLTA 4XBMA 3RR3A 4CUEA 4COXA 1NZIA 4LORA 4OTYA 1UZKA 1Z6EL 2FLRL 4RRZA 1EMNA 3F1SB 1CCVA 2P93L 1EGFA 1IQEL 2VVCK 2I9AA 5CKQA 4JZFL 1IQIL 1EZQB 5F19A 4LMFA 1CQEA 1DIYA 4D90A 1ADXA 3TK5B 2WPKE 3HO4A 4BTTA 4RS0A 2W2QE 1B9WA 3C9AC 1W7XL 3ELAL 3POYA 4E1GA 2W86A 2BO2A 5JBBE 1AUTL 2PUQL 2GD4A 1IGXA 4X8UL 1P0SL 3CENL 2W2ME 3TZIA 3U73A 3OLUA 2Y7ZB 3FCSB 4TGFA 2Y5FL 3ZYGA 2H9EL 1NFYB 3N8XA 3MDLA 1G1RA 1WHFA 1DQBA 3LAQA 5IKQA 2RHPA 1C5MF 4FM5A 3N8VA 5CISA 4Z0KB 1LPGA 3MQEA 3SOBB 3TH3L 3NTGA 2W26B 2K2TA 3FFGL 1EQHA 2FLGA 2VH0B 3HS6A 3PGHA 2VWMK 5JVYA 6COXA 4NG9L 1JL9A 1NFWB 4O1ZA 1UZJA 1XFEA 2WFXB 2W2NE 1IOEL 3HS5A 1WHEA 3QCWA 2VWOL 1CEJA 1JBUL 1YGCL 1KLIL 1APQA 2CJIB 1EMOA 2XBXL 2BOUA 1IJQA 2VVVL 4ZXXL 1G1QA 2XBVL 4RRWA 2UWLB 3U7UG 2BQ6A 3TK6B 4CUFA 4M11A 4O02B 3FBYA 3V64C 1KLOA 1IQFL 2J38B 4MMZB 1QFKL 2JKHL 4X8SL 5FDQA 2VJ3A 2KV4A 5IKTA 1L3YA 1L5GB 5CKNA 1KSNB 1KLJL 2VWLL 3N8WA 2MGRA 3QMOA 5IKRA 3GISX 2PHBB 1COUA 2W3IB 3CA7A 3CFWA 2J94B 2Y81B 1ATEA 4PH9A 4CUDA 1V3XB 1UZPA 1ATBA 3Q3KB 1IQHL 3BT1A 1U67A 2P94L 4A7IA 1FE2A 3DEMA 1LQDA 2AYLA 1ZAQA 3LN0A 5K0HB 2P3TA 3N8YB 2YGPA 4BDXA 4YT7L 1NPEB 4YT6L 3N8ZA 4Y6DB 1PFXL 2DDUA 2Y5HL 1IVOC 5L30L 2D1JB 2WG4B 1UZQA 1IOXA 1XKAL 1IQLL 2I9BA 1LMJA 1DDXA 2P3FL 4JZDL 2M74A 1JV2B 3ZYIB 1U8CB 1KIGL 3N8YA 3QH0A 3LTGD 2XBYL 2WPME 5COXA 2YGOA 1G1TA 1P9JA 4NGAL 3LIWB 4Y71B 2B7DL 3TBDA 1ATAA 1HREA 1EPHA 2WYJB 4JYUL 1PRHA 2FLBL 3NT1A 3F6UL 1K36A 5JW1A 5EGMB 4OTJA 1K37A 4XL1A 4JYVL 3KQCL 3ZYJB 2W2OE 1EBVA 1IP0A 1Q4GA 4BXWA 3V65B 1M1XB 3NTBA 4Z0LA 4MMYB 4Z6AL 2BMGA 1IQGL 2PR3B 2W2PE 3SOVA 2Y38A 2WFTA 1A3PA 1EAIC 1G2MB 1YUGA 3M37L 3HS7A 1HCGB 3N8WB 1TOZA 4ZH8B 2MGPA 4D0FA 1HJ7A 1LPKA 4YZUB 5L2YL 1IGZA 2KL7A 1MQ5L 2RA0L 3P5BL 1MOXC 1TLEA 1HRFA 5KIRA 1N1IA 1O5DL 4M10A 1EPJA 5JBCE 2VVUL 2WG3C 1NFXB 2Y80B 3TGFA 3K9XA 3KCGL 1CX2A 1W8BL 3GCWE 2UWPB 1BF9A 2W3KB 2XC0L 2J95B 3HO3A 5CKMA 2ADXA 1FF7A 1EPGA 2J34B 2P95L 2J4IB 3H5CB 2EI7B 4D0EA 2FD6A 1NQLB 4Y7BB 3GCXE 1NT0A 1Z6CA 2F9BL 5F1AA 3IJEB 1F7EA 4ISHL 4ZHAB 3SW2A 2TGFA 5KN5C 3M36L 2P3FN 1FAKL 2P16L 2BOKL 1F7MA 1XDTR 1HX2A 2XBWL 2OYUP 1IQKL 4Y79B 1FFMA 1FAXL 2BOXA 3Q7DA 1XKBA 5IKVA 5L2ZL 4C16A 4JZEL 2Y7XB 4RUTA 3KQEL 1APOA 1URKA 1IQJL 3BT2A 1F0RB 3LC5B 1EPIA 3HO5A 2P26A 1I0UA 1J9CL 1IQNL 2G00L 4XLWA 3EGFA 1CCFA 2XC5L 4RRYA 5JVZA 2WPHE 1IQML 2BQWA 2BOHA 2WYGB 4BTUA 2NPRA 3LN1A 4ZAEB 1RFNB 4NA9L 1X7AL 3KQBL 3IITB 3SOQA 1HT8A
chains in the Genus database with same CATH superfamily
1CVUA 4X8VL 1GK5A 3LTFB 1HAFA 1FSBA 5JB9E 1YUFA 4RRXA 1F0SB 2VH6B 3CS7L 1ATDA 2UWOB 2MHPA 4BXSA 4X8TL 4Y7AB 2P3UA 4AQTA 1TPGA 4BDWA 1G2LB 1CVWL 5I46L 1LPZA 1SZBA 2Y82B 2EI6B 3LC3B 4Y76B 4BTIA 2Q1JB 3KQDL 2FZZL 2OYEP 1WU1B 2BT8A 2JJLA 1DX5I 1HZ8A 3ENSA 2WPLE 1PTHA 1DVAL 1PXXA 1MQ6L 3HPTA 3KK6A 5JBAE 1NFUB 2KB9A 1PGEA 1HAEA 1OB1C 3NJPC 3KL6B 3ASIA 2WPIE 1HT5A 2BZ6L 2P28B 2K2SB 3KRKA 2VWNL 2XC4L 4G1MB 5JB8E 2WPJE 1YUKB 4ZXYL 1V1HA 3R05A 2RNLA 2Y5GL 4ISIL 1G1SA 3BPSE 5E8DA 2EI8B 1EQGA 1N7DA 1YO8A 2BQ7A 1FJSL 4MMXB 4CSYA 2J2UB 3OLTA 4XBMA 3RR3A 4CUEA 4COXA 1NZIA 4LORA 4OTYA 1UZKA 1Z6EL 2YGQA 2FLRL 4RRZA 1EMNA 3F1SB 1CCVA 2P93L 1EGFA 1IQEL 2VVCK 2I9AA 5CKQA 4JZFL 1IQIL 1EZQB 5F19A 4LMFA 1CQEA 1DIYA 4D90A 1ADXA 3TK5B 2WPKE 3HO4A 4BTTA 4RS0A 2W2QE 1B9WA 3C9AC 1W7XL 3ELAL 3POYA 4E1GA 2W86A 2BO2A 5JBBE 1AUTL 2PUQL 2GD4A 1IGXA 4X8UL 1P0SL 3CENL 2W2ME 2KNIA 3TZIA 3U73A 3OLUA 2Y7ZB 3FCSB 4TGFA 2Y5FL 3ZYGA 2H9EL 1NFYB 3N8XA 3MDLA 1G1RA 1WHFA 1DQBA 3LAQA 5IKQA 2RHPA 1C5MF 4FM5A 3N8VA 5CISA 4Z0KB 1LPGA 3MQEA 3SOBB 3TH3L 3NTGA 2WZPP 2W26B 2K2TA 3FFGL 1EQHA 2FLGA 2VH0B 3HS6A 3PGHA 2VWMK 5JVYA 6COXA 4NG9L 1JL9A 1NFWB 4O1ZA 1UZJA 1XFEA 2WFXB 2W2NE 1IOEL 3HS5A 1WHEA 3QCWA 2VWOL 1CEJA 1JBUL 1YGCL 1KLIL 1APQA 2CJIB 1EMOA 2XBXL 2BOUA 1IJQA 2VVVL 4ZXXL 1G1QA 2XBVL 4RRWA 2UWLB 3U7UG 2BQ6A 3TK6B 4CUFA 4M11A 4O02B 3FBYA 3V64C 1KLOA 1IQFL 2J38B 4MMZB 1QFKL 2JKHL 4X8SL 5FDQA 2VJ3A 2KV4A 5IKTA 1L3YA 1L5GB 5CKNA 1KSNB 1KLJL 2VWLL 3N8WA 2MGRA 3QMOA 5IKRA 3GISX 2PHBB 1COUA 2W3IB 3CA7A 3CFWA 2J94B 2Y81B 1ATEA 4PH9A 4CUDA 1V3XB 1UZPA 1ATBA 4GU3A 3Q3KB 1IQHL 2H9EC 3BT1A 1U67A 2P94L 4A7IA 1FE2A 3DEMA 1LQDA 2AYLA 1ZAQA 3LN0A 5K0HB 2P3TA 3N8YB 2YGPA 4BDXA 2HORA 4YT7L 1NPEB 1QIUA 4YT6L 3N8ZA 4Y6DB 1PFXL 2DDUA 2Y5HL 1IVOC 5L30L 2D1JB 2WG4B 1UZQA 1IOXA 1XKAL 1IQLL 2I9BA 1LMJA 2BSFA 1DDXA 2P3FL 4JZDL 2M74A 1JV2B 3ZYIB 1U8CB 1KIGL 3S6XA 3N8YA 3QH0A 3LTGD 2XBYL 2WPME 5COXA 2YGOA 1G1TA 1P9JA 4NGAL 3LIWB 4Y71B 2B7DL 3TBDA 1ATAA 1HREA 1EPHA 2WYJB 4JYUL 1PRHA 2FLBL 3NT1A 3F6UL 1K36A 5JW1A 5EGMB 4OTJA 1K37A 4XL1A 4JYVL 3KQCL 3ZYJB 2W2OE 1EBVA 1IP0A 1Q4GA 4BXWA 3V65B 1M1XB 3NTBA 4Z0LA 4MMYB 4Z6AL 2BMGA 1IQGL 2PR3B 2W2PE 3SOVA 2Y38A 2WFTA 1A3PA 1EAIC 1G2MB 1YUGA 3M37L 3HS7A 1HCGB 3N8WB 1TOZA 4ZH8B 1LK9A 2MGPA 4D0FA 1HJ7A 1LPKA 2VRSA 4YZUB 5L2YL 1IGZA 2KL7A 1MQ5L 2RA0L 3P5BL 1MOXC 1TLEA 1HRFA 5KIRA 1N1IA 1O5DL 4GU4A 4M10A 1EPJA 5JBCE 2VVUL 2WG3C 1NFXB 2Y80B 3TGFA 3K9XA 3KCGL 1CX2A 1W8BL 1V1IA 3GCWE 2UWPB 4A94C 1BF9A 2W3KB 2XC0L 2J95B 3HO3A 5CKMA 2ADXA 1FF7A 1EPGA 2J34B 2P95L 2J4IB 3H5CB 2EI7B 4D0EA 2FD6A 1NQLB 4Y7BB 3GCXE 1NT0A 1Z6CA 1LMMA 2F9BL 5F1AA 3IJEB 1F7EA 4ISHL 4ZHAB 3SW2A 2BT7A 2TGFA 5KN5C 3M36L 2P3FN 1FAKL 2P16L 2BOKL 1F7MA 1XDTR 1HX2A 2XBWL 2OYUP 1KKEA 1IQKL 4Y79B 1FFMA 1FAXL 2BOXA 3Q7DA 1XKBA 5IKVA 5L2ZL 4C16A 4JZEL 2Y7XB 4RUTA 3KQEL 1APOA 1URKA 1IQJL 3BT2A 1F0RB 3LC5B 1EPIA 3HO5A 2P26A 1I0UA 1J9CL 1IQNL 2G00L 4XLWA 2HOXA 3EGFA 1CCFA 2XC5L 4RRYA 5JVZA 2WPHE 1IQML 2BQWA 2BOHA 2WYGB 4BTUA 2NPRA 3LN1A 4ZAEB 1RFNB 4NA9L 1X7AL 3KQBL 3IITB 3SOQA 1HT8A
chains in the Genus database with same CATH topology
1CVUA 4X8VL 1GK5A 3LTFB 1HAFA 1FSBA 5JB9E 1YUFA 4RRXA 1F0SB 2VH6B 3CS7L 1ATDA 2UWOB 2MHPA 4BXSA 4X8TL 4Y7AB 2P3UA 4AQTA 1TPGA 4BDWA 1G2LB 1CVWL 5I46L 1LPZA 1SZBA 2Y82B 2EI6B 3LC3B 4Y76B 4BTIA 2Q1JB 3KQDL 2FZZL 2OYEP 1WU1B 1DX5I 1HZ8A 3ENSA 2WPLE 1PTHA 1DVAL 1PXXA 1MQ6L 3HPTA 3KK6A 5JBAE 1NFUB 2KB9A 1PGEA 1HAEA 1OB1C 3NJPC 3KL6B 3ASIA 2WPIE 1HT5A 2BZ6L 2P28B 2K2SB 3KRKA 2VWNL 2XC4L 4G1MB 5JB8E 2WPJE 1YUKB 4ZXYL 3R05A 2RNLA 2Y5GL 4ISIL 1G1SA 3BPSE 5E8DA 2EI8B 1EQGA 1N7DA 1YO8A 2BQ7A 1FJSL 4MMXB 4CSYA 2J2UB 3OLTA 4XBMA 3RR3A 4CUEA 4COXA 1NZIA 4LORA 4OTYA 1UZKA 1Z6EL 2YGQA 2FLRL 4RRZA 1EMNA 3F1SB 1CCVA 2P93L 1EGFA 1IQEL 2VVCK 2I9AA 5CKQA 4JZFL 1IQIL 1EZQB 5F19A 4LMFA 1CQEA 1DIYA 4D90A 1ADXA 3TK5B 2WPKE 3HO4A 4BTTA 4RS0A 2W2QE 1B9WA 3C9AC 1W7XL 3ELAL 3POYA 4E1GA 2W86A 2BO2A 5JBBE 1AUTL 2PUQL 2GD4A 1IGXA 4X8UL 1P0SL 3CENL 2W2ME 2KNIA 3TZIA 3U73A 3OLUA 2Y7ZB 3FCSB 4TGFA 2Y5FL 3ZYGA 2H9EL 1NFYB 3N8XA 3MDLA 1G1RA 1WHFA 1DQBA 3LAQA 5IKQA 2RHPA 1C5MF 4FM5A 3N8VA 5CISA 4Z0KB 1LPGA 3MQEA 3SOBB 3TH3L 3NTGA 2WZPP 2W26B 2K2TA 3FFGL 1EQHA 2FLGA 2VH0B 3HS6A 3PGHA 2VWMK 5JVYA 6COXA 4NG9L 1JL9A 1NFWB 4O1ZA 1UZJA 1XFEA 2WFXB 2W2NE 1IOEL 3HS5A 1WHEA 3QCWA 2VWOL 1CEJA 1JBUL 1YGCL 1KLIL 1APQA 2CJIB 1EMOA 2XBXL 2BOUA 1IJQA 2VVVL 4ZXXL 1G1QA 2XBVL 4RRWA 2UWLB 3U7UG 2BQ6A 3TK6B 4CUFA 4M11A 4O02B 3FBYA 3V64C 1KLOA 1IQFL 2J38B 4MMZB 1QFKL 2JKHL 4X8SL 5FDQA 2VJ3A 2KV4A 5IKTA 1L3YA 1L5GB 5CKNA 1KSNB 1KLJL 2VWLL 3N8WA 2MGRA 3QMOA 5IKRA 3GISX 2PHBB 1COUA 2W3IB 3CA7A 3CFWA 2J94B 2Y81B 1ATEA 4PH9A 4CUDA 1V3XB 1UZPA 1ATBA 3Q3KB 1IQHL 2H9EC 3BT1A 1U67A 2P94L 4A7IA 1FE2A 3DEMA 1LQDA 2AYLA 1ZAQA 3LN0A 5K0HB 2P3TA 3N8YB 2YGPA 4BDXA 4YT7L 1NPEB 4YT6L 3N8ZA 4Y6DB 1PFXL 2DDUA 2Y5HL 1IVOC 5L30L 2D1JB 2WG4B 1UZQA 1IOXA 1XKAL 1IQLL 2I9BA 1LMJA 1DDXA 2P3FL 4JZDL 2M74A 1JV2B 3ZYIB 1U8CB 1KIGL 3S6XA 3N8YA 3QH0A 3LTGD 2XBYL 2WPME 5COXA 2YGOA 1G1TA 1P9JA 4NGAL 3LIWB 4Y71B 2B7DL 3TBDA 1ATAA 1HREA 1EPHA 2WYJB 4JYUL 1PRHA 2FLBL 3NT1A 3F6UL 1K36A 5JW1A 5EGMB 4OTJA 1K37A 4XL1A 4JYVL 3KQCL 3ZYJB 2W2OE 1EBVA 1IP0A 1Q4GA 4BXWA 3V65B 1M1XB 3NTBA 4Z0LA 4MMYB 4Z6AL 2BMGA 1IQGL 2PR3B 2W2PE 3SOVA 2Y38A 2WFTA 1A3PA 1EAIC 1G2MB 1YUGA 3M37L 3HS7A 1HCGB 3N8WB 1TOZA 4ZH8B 2MGPA 4D0FA 1HJ7A 1LPKA 4YZUB 5L2YL 1IGZA 2KL7A 1MQ5L 2RA0L 3P5BL 1MOXC 1TLEA 1HRFA 5KIRA 1N1IA 1O5DL 4M10A 1EPJA 5JBCE 2VVUL 2WG3C 1NFXB 2Y80B 3TGFA 3K9XA 3KCGL 1CX2A 1W8BL 3GCWE 2UWPB 4A94C 1BF9A 2W3KB 2XC0L 2J95B 3HO3A 5CKMA 2ADXA 1FF7A 1EPGA 2J34B 2P95L 2J4IB 3H5CB 2EI7B 4D0EA 2FD6A 1NQLB 4Y7BB 3GCXE 1NT0A 1Z6CA 1LMMA 2F9BL 5F1AA 3IJEB 1F7EA 4ISHL 4ZHAB 3SW2A 2TGFA 5KN5C 3M36L 2P3FN 1FAKL 2P16L 2BOKL 1F7MA 1XDTR 1HX2A 2XBWL 2OYUP 1IQKL 4Y79B 1FFMA 1FAXL 2BOXA 3Q7DA 1XKBA 5IKVA 5L2ZL 4C16A 4JZEL 2Y7XB 4RUTA 3KQEL 1APOA 1URKA 1IQJL 3BT2A 1F0RB 3LC5B 1EPIA 3HO5A 2P26A 1I0UA 1J9CL 1IQNL 2G00L 4XLWA 3EGFA 1CCFA 2XC5L 4RRYA 5JVZA 2WPHE 1IQML 2BQWA 2BOHA 2WYGB 4BTUA 2NPRA 3LN1A 4ZAEB 1RFNB 4NA9L 1X7AL 3KQBL 3IITB 3SOQA 1HT8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CVU A;  4X8V L;  1GK5 A;  3LTF B;  1HAF A;  1FSB A;  5JB9 E;  1YUF A;  4RRX A;  1F0S B;  2VH6 B;  3CS7 L;  1ATD A;  2UWO B;  2MHP A;  4BXS A;  4X8T L;  4Y7A B;  2P3U A;  4AQT A;  1TPG A;  4BDW A;  1G2L B;  1CVW L;  5I46 L;  1LPZ A;  1SZB A;  2Y82 B;  2EI6 B;  3LC3 B;  4Y76 B;  4BTI A;  2Q1J B;  3KQD L;  2FZZ L;  2OYE P;  1WU1 B;  1DX5 I;  1HZ8 A;  3ENS A;  2WPL E;  1PTH A;  1DVA L;  1PXX A;  1MQ6 L;  3HPT A;  3KK6 A;  5JBA E;  1NFU B;  2KB9 A;  1PGE A;  1HAE A;  1OB1 C;  3NJP C;  3KL6 B;  3ASI A;  2WPI E;  1HT5 A;  2BZ6 L;  2P28 B;  2K2S B;  3KRK A;  2VWN L;  2XC4 L;  4G1M B;  5JB8 E;  2WPJ E;  1YUK B;  4ZXY L;  3R05 A;  2RNL A;  2Y5G L;  4ISI L;  1G1S A;  3BPS E;  5E8D A;  2EI8 B;  1EQG A;  1N7D A;  1YO8 A;  2BQ7 A;  1FJS L;  4MMX B;  4CSY A;  2J2U B;  3OLT A;  4XBM A;  3RR3 A;  4CUE A;  4COX A;  1NZI A;  4LOR A;  4OTY A;  1UZK A;  1Z6E L;  2FLR L;  4RRZ A;  1EMN A;  3F1S B;  1CCV A;  2P93 L;  1EGF A;  1IQE L;  2VVC K;  2I9A A;  5CKQ A;  4JZF L;  1IQI L;  1EZQ B;  5F19 A;  4LMF A;  1CQE A;  1DIY A;  4D90 A;  1ADX A;  3TK5 B;  2WPK E;  3HO4 A;  4BTT A;  4RS0 A;  2W2Q E;  1B9W A;  3C9A C;  1W7X L;  3ELA L;  3POY A;  4E1G A;  2W86 A;  2BO2 A;  5JBB E;  1AUT L;  2PUQ L;  2GD4 A;  1IGX A;  4X8U L;  1P0S L;  3CEN L;  2W2M E;  3TZI A;  3U73 A;  3OLU A;  2Y7Z B;  3FCS B;  4TGF A;  2Y5F L;  3ZYG A;  2H9E L;  1NFY B;  3N8X A;  3MDL A;  1G1R A;  1WHF A;  1DQB A;  3LAQ A;  5IKQ A;  2RHP A;  1C5M F;  4FM5 A;  3N8V A;  5CIS A;  4Z0K B;  1LPG A;  3MQE A;  3SOB B;  3TH3 L;  3NTG A;  2W26 B;  2K2T A;  3FFG L;  1EQH A;  2FLG A;  2VH0 B;  3HS6 A;  3PGH A;  2VWM K;  5JVY A;  6COX A;  4NG9 L;  1JL9 A;  1NFW B;  4O1Z A;  1UZJ A;  1XFE A;  2WFX B;  2W2N E;  1IOE L;  3HS5 A;  1WHE A;  3QCW A;  2VWO L;  1CEJ A;  1JBU L;  1YGC L;  1KLI L;  1APQ A;  2CJI B;  1EMO A;  2XBX L;  2BOU A;  1IJQ A;  2VVV L;  4ZXX L;  1G1Q A;  2XBV L;  4RRW A;  2UWL B;  3U7U G;  2BQ6 A;  3TK6 B;  4CUF A;  4M11 A;  4O02 B;  3FBY A;  3V64 C;  1KLO A;  1IQF L;  2J38 B;  4MMZ B;  1QFK L;  2JKH L;  4X8S L;  5FDQ A;  2VJ3 A;  2KV4 A;  5IKT A;  1L3Y A;  1L5G B;  5CKN A;  1KSN B;  1KLJ L;  2VWL L;  3N8W A;  2MGR A;  3QMO A;  5IKR A;  3GIS X;  2PHB B;  1COU A;  2W3I B;  3CA7 A;  3CFW A;  2J94 B;  2Y81 B;  1ATE A;  4PH9 A;  4CUD A;  1V3X B;  1UZP A;  1ATB A;  3Q3K B;  1IQH L;  3BT1 A;  1U67 A;  2P94 L;  4A7I A;  1FE2 A;  3DEM A;  1LQD A;  2AYL A;  1ZAQ A;  3LN0 A;  5K0H B;  2P3T A;  3N8Y B;  2YGP A;  4BDX A;  4YT7 L;  1NPE B;  4YT6 L;  3N8Z A;  4Y6D B;  1PFX L;  2DDU A;  2Y5H L;  1IVO C;  5L30 L;  2D1J B;  2WG4 B;  1UZQ A;  1IOX A;  1XKA L;  1IQL L;  2I9B A;  1LMJ A;  1DDX A;  2P3F L;  4JZD L;  2M74 A;  1JV2 B;  3ZYI B;  1U8C B;  1KIG L;  3N8Y A;  3QH0 A;  3LTG D;  2XBY L;  2WPM E;  5COX A;  2YGO A;  1G1T A;  1P9J A;  4NGA L;  3LIW B;  4Y71 B;  2B7D L;  3TBD A;  1ATA A;  1HRE A;  1EPH A;  2WYJ B;  4JYU L;  1PRH A;  2FLB L;  3NT1 A;  3F6U L;  1K36 A;  5JW1 A;  5EGM B;  4OTJ A;  1K37 A;  4XL1 A;  4JYV L;  3KQC L;  3ZYJ B;  2W2O E;  1EBV A;  1IP0 A;  1Q4G A;  4BXW A;  3V65 B;  1M1X B;  3NTB A;  4Z0L A;  4MMY B;  4Z6A L;  2BMG A;  1IQG L;  2PR3 B;  2W2P E;  3SOV A;  2Y38 A;  2WFT A;  1A3P A;  1EAI C;  1G2M B;  1YUG A;  3M37 L;  3HS7 A;  1HCG B;  3N8W B;  1TOZ A;  4ZH8 B;  2MGP A;  4D0F A;  1HJ7 A;  1LPK A;  4YZU B;  5L2Y L;  1IGZ A;  2KL7 A;  1MQ5 L;  2RA0 L;  3P5B L;  1MOX C;  1TLE A;  1HRF A;  5KIR A;  1N1I A;  1O5D L;  4M10 A;  1EPJ A;  5JBC E;  2VVU L;  2WG3 C;  1NFX B;  2Y80 B;  3TGF A;  3K9X A;  3KCG L;  1CX2 A;  1W8B L;  3GCW E;  2UWP B;  1BF9 A;  2W3K B;  2XC0 L;  2J95 B;  3HO3 A;  5CKM A;  2ADX A;  1FF7 A;  1EPG A;  2J34 B;  2P95 L;  2J4I B;  3H5C B;  2EI7 B;  4D0E A;  2FD6 A;  1NQL B;  4Y7B B;  3GCX E;  1NT0 A;  1Z6C A;  2F9B L;  5F1A A;  3IJE B;  1F7E A;  4ISH L;  4ZHA B;  3SW2 A;  2TGF A;  5KN5 C;  3M36 L;  2P3F N;  1FAK L;  2P16 L;  2BOK L;  1F7M A;  1XDT R;  1HX2 A;  2XBW L;  2OYU P;  1IQK L;  4Y79 B;  1FFM A;  1FAX L;  2BOX A;  3Q7D A;  1XKB A;  5IKV A;  5L2Z L;  4C16 A;  4JZE L;  2Y7X B;  4RUT A;  3KQE L;  1APO A;  1URK A;  1IQJ L;  3BT2 A;  1F0R B;  3LC5 B;  1EPI A;  3HO5 A;  2P26 A;  1I0U A;  1J9C L;  1IQN L;  2G00 L;  4XLW A;  3EGF A;  1CCF A;  2XC5 L;  4RRY A;  5JVZ A;  2WPH E;  1IQM L;  2BQW A;  2BOH A;  2WYG B;  4BTU A;  2NPR A;  3LN1 A;  4ZAE B;  1RFN B;  4NA9 L;  1X7A L;  3KQB L;  3IIT B;  3SOQ A;  1HT8 A; 
#chains in the Genus database with same CATH topology
 1CVU A;  4X8V L;  1GK5 A;  3LTF B;  1HAF A;  1FSB A;  5JB9 E;  1YUF A;  4RRX A;  1F0S B;  2VH6 B;  3CS7 L;  1ATD A;  2UWO B;  2MHP A;  4BXS A;  4X8T L;  4Y7A B;  2P3U A;  4AQT A;  1TPG A;  4BDW A;  1G2L B;  1CVW L;  5I46 L;  1LPZ A;  1SZB A;  2Y82 B;  2EI6 B;  3LC3 B;  4Y76 B;  4BTI A;  2Q1J B;  3KQD L;  2FZZ L;  2OYE P;  1WU1 B;  2BT8 A;  2JJL A;  1DX5 I;  1HZ8 A;  3ENS A;  2WPL E;  1PTH A;  1DVA L;  1PXX A;  1MQ6 L;  3HPT A;  3KK6 A;  5JBA E;  1NFU B;  2KB9 A;  1PGE A;  1HAE A;  1OB1 C;  3NJP C;  3KL6 B;  3ASI A;  2WPI E;  1HT5 A;  2BZ6 L;  2P28 B;  2K2S B;  3KRK A;  2VWN L;  2XC4 L;  4G1M B;  5JB8 E;  2WPJ E;  1YUK B;  4ZXY L;  1V1H A;  3R05 A;  2RNL A;  2Y5G L;  4ISI L;  1G1S A;  3BPS E;  5E8D A;  2EI8 B;  1EQG A;  1N7D A;  1YO8 A;  2BQ7 A;  1FJS L;  4MMX B;  4CSY A;  2J2U B;  3OLT A;  4XBM A;  3RR3 A;  4CUE A;  4COX A;  1NZI A;  4LOR A;  4OTY A;  1UZK A;  1Z6E L;  2YGQ A;  2FLR L;  4RRZ A;  1EMN A;  3F1S B;  1CCV A;  2P93 L;  1EGF A;  1IQE L;  2VVC K;  2I9A A;  5CKQ A;  4JZF L;  1IQI L;  1EZQ B;  5F19 A;  4LMF A;  1CQE A;  1DIY A;  4D90 A;  1ADX A;  3TK5 B;  2WPK E;  3HO4 A;  4BTT A;  4RS0 A;  2W2Q E;  1B9W A;  3C9A C;  1W7X L;  3ELA L;  3POY A;  4E1G A;  2W86 A;  2BO2 A;  5JBB E;  1AUT L;  2PUQ L;  2GD4 A;  1IGX A;  4X8U L;  1P0S L;  3CEN L;  2W2M E;  2KNI A;  3TZI A;  3U73 A;  3OLU A;  2Y7Z B;  3FCS B;  4TGF A;  2Y5F L;  3ZYG A;  2H9E L;  1NFY B;  3N8X A;  3MDL A;  1G1R A;  1WHF A;  1DQB A;  3LAQ A;  5IKQ A;  2RHP A;  1C5M F;  4FM5 A;  3N8V A;  5CIS A;  4Z0K B;  1LPG A;  3MQE A;  3SOB B;  3TH3 L;  3NTG A;  2WZP P;  2W26 B;  2K2T A;  3FFG L;  1EQH A;  2FLG A;  2VH0 B;  3HS6 A;  3PGH A;  2VWM K;  5JVY A;  6COX A;  4NG9 L;  1JL9 A;  1NFW B;  4O1Z A;  1UZJ A;  1XFE A;  2WFX B;  2W2N E;  1IOE L;  3HS5 A;  1WHE A;  3QCW A;  2VWO L;  1CEJ A;  1JBU L;  1YGC L;  1KLI L;  1APQ A;  2CJI B;  1EMO A;  2XBX L;  2BOU A;  1IJQ A;  2VVV L;  4ZXX L;  1G1Q A;  2XBV L;  4RRW A;  2UWL B;  3U7U G;  2BQ6 A;  3TK6 B;  4CUF A;  4M11 A;  4O02 B;  3FBY A;  3V64 C;  1KLO A;  1IQF L;  2J38 B;  4MMZ B;  1QFK L;  2JKH L;  4X8S L;  5FDQ A;  2VJ3 A;  2KV4 A;  5IKT A;  1L3Y A;  1L5G B;  5CKN A;  1KSN B;  1KLJ L;  2VWL L;  3N8W A;  2MGR A;  3QMO A;  5IKR A;  3GIS X;  2PHB B;  1COU A;  2W3I B;  3CA7 A;  3CFW A;  2J94 B;  2Y81 B;  1ATE A;  4PH9 A;  4CUD A;  1V3X B;  1UZP A;  1ATB A;  4GU3 A;  3Q3K B;  1IQH L;  2H9E C;  3BT1 A;  1U67 A;  2P94 L;  4A7I A;  1FE2 A;  3DEM A;  1LQD A;  2AYL A;  1ZAQ A;  3LN0 A;  5K0H B;  2P3T A;  3N8Y B;  2YGP A;  4BDX A;  2HOR A;  4YT7 L;  1NPE B;  1QIU A;  4YT6 L;  3N8Z A;  4Y6D B;  1PFX L;  2DDU A;  2Y5H L;  1IVO C;  5L30 L;  2D1J B;  2WG4 B;  1UZQ A;  1IOX A;  1XKA L;  1IQL L;  2I9B A;  1LMJ A;  2BSF A;  1DDX A;  2P3F L;  4JZD L;  2M74 A;  1JV2 B;  3ZYI B;  1U8C B;  1KIG L;  3S6X A;  3N8Y A;  3QH0 A;  3LTG D;  2XBY L;  2WPM E;  5COX A;  2YGO A;  1G1T A;  1P9J A;  4NGA L;  3LIW B;  4Y71 B;  2B7D L;  3TBD A;  1ATA A;  1HRE A;  1EPH A;  2WYJ B;  4JYU L;  1PRH A;  2FLB L;  3NT1 A;  3F6U L;  1K36 A;  5JW1 A;  5EGM B;  4OTJ A;  1K37 A;  4XL1 A;  4JYV L;  3KQC L;  3ZYJ B;  2W2O E;  1EBV A;  1IP0 A;  1Q4G A;  4BXW A;  3V65 B;  1M1X B;  3NTB A;  4Z0L A;  4MMY B;  4Z6A L;  2BMG A;  1IQG L;  2PR3 B;  2W2P E;  3SOV A;  2Y38 A;  2WFT A;  1A3P A;  1EAI C;  1G2M B;  1YUG A;  3M37 L;  3HS7 A;  1HCG B;  3N8W B;  1TOZ A;  4ZH8 B;  1LK9 A;  2MGP A;  4D0F A;  1HJ7 A;  1LPK A;  2VRS A;  4YZU B;  5L2Y L;  1IGZ A;  2KL7 A;  1MQ5 L;  2RA0 L;  3P5B L;  1MOX C;  1TLE A;  1HRF A;  5KIR A;  1N1I A;  1O5D L;  4GU4 A;  4M10 A;  1EPJ A;  5JBC E;  2VVU L;  2WG3 C;  1NFX B;  2Y80 B;  3TGF A;  3K9X A;  3KCG L;  1CX2 A;  1W8B L;  1V1I A;  3GCW E;  2UWP B;  4A94 C;  1BF9 A;  2W3K B;  2XC0 L;  2J95 B;  3HO3 A;  5CKM A;  2ADX A;  1FF7 A;  1EPG A;  2J34 B;  2P95 L;  2J4I B;  3H5C B;  2EI7 B;  4D0E A;  2FD6 A;  1NQL B;  4Y7B B;  3GCX E;  1NT0 A;  1Z6C A;  1LMM A;  2F9B L;  5F1A A;  3IJE B;  1F7E A;  4ISH L;  4ZHA B;  3SW2 A;  2BT7 A;  2TGF A;  5KN5 C;  3M36 L;  2P3F N;  1FAK L;  2P16 L;  2BOK L;  1F7M A;  1XDT R;  1HX2 A;  2XBW L;  2OYU P;  1KKE A;  1IQK L;  4Y79 B;  1FFM A;  1FAX L;  2BOX A;  3Q7D A;  1XKB A;  5IKV A;  5L2Z L;  4C16 A;  4JZE L;  2Y7X B;  4RUT A;  3KQE L;  1APO A;  1URK A;  1IQJ L;  3BT2 A;  1F0R B;  3LC5 B;  1EPI A;  3HO5 A;  2P26 A;  1I0U A;  1J9C L;  1IQN L;  2G00 L;  4XLW A;  2HOX A;  3EGF A;  1CCF A;  2XC5 L;  4RRY A;  5JVZ A;  2WPH E;  1IQM L;  2BQW A;  2BOH A;  2WYG B;  4BTU A;  2NPR A;  3LN1 A;  4ZAE B;  1RFN B;  4NA9 L;  1X7A L;  3KQB L;  3IIT B;  3SOQ A;  1HT8 A; 
#chains in the Genus database with same CATH homology
 1CVU A;  4X8V L;  1GK5 A;  3LTF B;  1HAF A;  1FSB A;  5JB9 E;  1YUF A;  4RRX A;  1F0S B;  2VH6 B;  3CS7 L;  1ATD A;  2UWO B;  2MHP A;  4BXS A;  4X8T L;  4Y7A B;  2P3U A;  4AQT A;  1TPG A;  4BDW A;  1G2L B;  1CVW L;  5I46 L;  1LPZ A;  1SZB A;  2Y82 B;  2EI6 B;  3LC3 B;  4Y76 B;  4BTI A;  2Q1J B;  3KQD L;  2FZZ L;  2OYE P;  1WU1 B;  1DX5 I;  1HZ8 A;  3ENS A;  2WPL E;  1PTH A;  1DVA L;  1PXX A;  1MQ6 L;  3HPT A;  3KK6 A;  5JBA E;  1NFU B;  2KB9 A;  1PGE A;  1HAE A;  1OB1 C;  3NJP C;  3KL6 B;  3ASI A;  2WPI E;  1HT5 A;  2BZ6 L;  2P28 B;  2K2S B;  3KRK A;  2VWN L;  2XC4 L;  4G1M B;  5JB8 E;  2WPJ E;  1YUK B;  4ZXY L;  3R05 A;  2RNL A;  2Y5G L;  4ISI L;  1G1S A;  3BPS E;  5E8D A;  2EI8 B;  1EQG A;  1N7D A;  1YO8 A;  2BQ7 A;  1FJS L;  4MMX B;  4CSY A;  2J2U B;  3OLT A;  4XBM A;  3RR3 A;  4CUE A;  4COX A;  1NZI A;  4LOR A;  4OTY A;  1UZK A;  1Z6E L;  2YGQ A;  2FLR L;  4RRZ A;  1EMN A;  3F1S B;  1CCV A;  2P93 L;  1EGF A;  1IQE L;  2VVC K;  2I9A A;  5CKQ A;  4JZF L;  1IQI L;  1EZQ B;  5F19 A;  4LMF A;  1CQE A;  1DIY A;  4D90 A;  1ADX A;  3TK5 B;  2WPK E;  3HO4 A;  4BTT A;  4RS0 A;  2W2Q E;  1B9W A;  3C9A C;  1W7X L;  3ELA L;  3POY A;  4E1G A;  2W86 A;  2BO2 A;  5JBB E;  1AUT L;  2PUQ L;  2GD4 A;  1IGX A;  4X8U L;  1P0S L;  3CEN L;  2W2M E;  2KNI A;  3TZI A;  3U73 A;  3OLU A;  2Y7Z B;  3FCS B;  4TGF A;  2Y5F L;  3ZYG A;  2H9E L;  1NFY B;  3N8X A;  3MDL A;  1G1R A;  1WHF A;  1DQB A;  3LAQ A;  5IKQ A;  2RHP A;  1C5M F;  4FM5 A;  3N8V A;  5CIS A;  4Z0K B;  1LPG A;  3MQE A;  3SOB B;  3TH3 L;  3NTG A;  2WZP P;  2W26 B;  2K2T A;  3FFG L;  1EQH A;  2FLG A;  2VH0 B;  3HS6 A;  3PGH A;  2VWM K;  5JVY A;  6COX A;  4NG9 L;  1JL9 A;  1NFW B;  4O1Z A;  1UZJ A;  1XFE A;  2WFX B;  2W2N E;  1IOE L;  3HS5 A;  1WHE A;  3QCW A;  2VWO L;  1CEJ A;  1JBU L;  1YGC L;  1KLI L;  1APQ A;  2CJI B;  1EMO A;  2XBX L;  2BOU A;  1IJQ A;  2VVV L;  4ZXX L;  1G1Q A;  2XBV L;  4RRW A;  2UWL B;  3U7U G;  2BQ6 A;  3TK6 B;  4CUF A;  4M11 A;  4O02 B;  3FBY A;  3V64 C;  1KLO A;  1IQF L;  2J38 B;  4MMZ B;  1QFK L;  2JKH L;  4X8S L;  5FDQ A;  2VJ3 A;  2KV4 A;  5IKT A;  1L3Y A;  1L5G B;  5CKN A;  1KSN B;  1KLJ L;  2VWL L;  3N8W A;  2MGR A;  3QMO A;  5IKR A;  3GIS X;  2PHB B;  1COU A;  2W3I B;  3CA7 A;  3CFW A;  2J94 B;  2Y81 B;  1ATE A;  4PH9 A;  4CUD A;  1V3X B;  1UZP A;  1ATB A;  3Q3K B;  1IQH L;  2H9E C;  3BT1 A;  1U67 A;  2P94 L;  4A7I A;  1FE2 A;  3DEM A;  1LQD A;  2AYL A;  1ZAQ A;  3LN0 A;  5K0H B;  2P3T A;  3N8Y B;  2YGP A;  4BDX A;  4YT7 L;  1NPE B;  4YT6 L;  3N8Z A;  4Y6D B;  1PFX L;  2DDU A;  2Y5H L;  1IVO C;  5L30 L;  2D1J B;  2WG4 B;  1UZQ A;  1IOX A;  1XKA L;  1IQL L;  2I9B A;  1LMJ A;  1DDX A;  2P3F L;  4JZD L;  2M74 A;  1JV2 B;  3ZYI B;  1U8C B;  1KIG L;  3S6X A;  3N8Y A;  3QH0 A;  3LTG D;  2XBY L;  2WPM E;  5COX A;  2YGO A;  1G1T A;  1P9J A;  4NGA L;  3LIW B;  4Y71 B;  2B7D L;  3TBD A;  1ATA A;  1HRE A;  1EPH A;  2WYJ B;  4JYU L;  1PRH A;  2FLB L;  3NT1 A;  3F6U L;  1K36 A;  5JW1 A;  5EGM B;  4OTJ A;  1K37 A;  4XL1 A;  4JYV L;  3KQC L;  3ZYJ B;  2W2O E;  1EBV A;  1IP0 A;  1Q4G A;  4BXW A;  3V65 B;  1M1X B;  3NTB A;  4Z0L A;  4MMY B;  4Z6A L;  2BMG A;  1IQG L;  2PR3 B;  2W2P E;  3SOV A;  2Y38 A;  2WFT A;  1A3P A;  1EAI C;  1G2M B;  1YUG A;  3M37 L;  3HS7 A;  1HCG B;  3N8W B;  1TOZ A;  4ZH8 B;  2MGP A;  4D0F A;  1HJ7 A;  1LPK A;  4YZU B;  5L2Y L;  1IGZ A;  2KL7 A;  1MQ5 L;  2RA0 L;  3P5B L;  1MOX C;  1TLE A;  1HRF A;  5KIR A;  1N1I A;  1O5D L;  4M10 A;  1EPJ A;  5JBC E;  2VVU L;  2WG3 C;  1NFX B;  2Y80 B;  3TGF A;  3K9X A;  3KCG L;  1CX2 A;  1W8B L;  3GCW E;  2UWP B;  4A94 C;  1BF9 A;  2W3K B;  2XC0 L;  2J95 B;  3HO3 A;  5CKM A;  2ADX A;  1FF7 A;  1EPG A;  2J34 B;  2P95 L;  2J4I B;  3H5C B;  2EI7 B;  4D0E A;  2FD6 A;  1NQL B;  4Y7B B;  3GCX E;  1NT0 A;  1Z6C A;  1LMM A;  2F9B L;  5F1A A;  3IJE B;  1F7E A;  4ISH L;  4ZHA B;  3SW2 A;  2TGF A;  5KN5 C;  3M36 L;  2P3F N;  1FAK L;  2P16 L;  2BOK L;  1F7M A;  1XDT R;  1HX2 A;  2XBW L;  2OYU P;  1IQK L;  4Y79 B;  1FFM A;  1FAX L;  2BOX A;  3Q7D A;  1XKB A;  5IKV A;  5L2Z L;  4C16 A;  4JZE L;  2Y7X B;  4RUT A;  3KQE L;  1APO A;  1URK A;  1IQJ L;  3BT2 A;  1F0R B;  3LC5 B;  1EPI A;  3HO5 A;  2P26 A;  1I0U A;  1J9C L;  1IQN L;  2G00 L;  4XLW A;  3EGF A;  1CCF A;  2XC5 L;  4RRY A;  5JVZ A;  2WPH E;  1IQM L;  2BQW A;  2BOH A;  2WYG B;  4BTU A;  2NPR A;  3LN1 A;  4ZAE B;  1RFN B;  4NA9 L;  1X7A L;  3KQB L;  3IIT B;  3SOQ A;  1HT8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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