4X8SL

Factor viia in complex with the inhibitor 4-bromo-2-methoxyphenol
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
55
structure length
55
Chain Sequence
ICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Novel P1 Groups for Coagulation Factor VIIa Inhibition Using Fragment-Based Screening.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Factor VIIa (Heavy Chain)
total genus 13
structure length 55
sequence length 55
ec nomenclature ec 3.4.21.21: Coagulation factor VIIa.
pdb deposition date 2014-12-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 4x8sL00
1WHEA 1IQKL 1K36A 3IJEB 2VWNL 1ATBA 3NJPC 2JKHL 3LN1A 5CKNA 2BMGA 4Y76B 2BO2A 2P3FL 2W26B 3MQEA 1ZAQA 1EPJA 2FLGA 2BQWA 1IQJL 1IOEL 1B9WA 1UZQA 2KL7A 4LMFA 4XLWA 1IQFL 1DIYA 3MDLA 4Y7BB 3NT1A 3H5CB 1DQBA 2W2QE 3SOQA 4CUDA 2D1JB 3BT1A 1XKAL 2B7DL 1U8CB 4M11A 3LAQA 1O5DL 5CISA 2YGOA 1EMOA 1P0SL 5KIRA 2I9AA 1G1RA 2Y5HL 1IJQA 1KLJL 1Z6EL 5JBAE 3ELAL 2G00L 5F19A 4X8UL 2BOXA 1HZ8A 4BTIA 2XC0L 3LC5B 2W3IB 2WFTA 2W2ME 4Y71B 4G1MB 1KSNB 5IKRA 2WPJE 2FZZL 3SOVA 1YGCL 1G1QA 4YT6L 2WYJB 2WG4B 5L2ZL 1DX5I 1HJ7A 4BTTA 1UZKA 2BQ7A 2UWOB 1QFKL 3PGHA 1KLIL 4JZFL 1ATEA 2Y82B 2Y81B 3HS7A 5JW1A 3TH3L 2J94B 3N8WA 3NTGA 4XBMA 5K0HB 1EZQB 4OTYA 1HRFA 5EGMB 2P3FN 4X8SL 2H9EL 3F6UL 2K2TA 2UWLB 1IP0A 5JBBE 1JBUL 4BXSA 5L30L 2WYGB 4BXWA 2KB9A 4NGAL 1HAFA 3ENSA 2FD6A 3KQBL 4ZXXL 1HX2A 2BZ6L 2J34B 4Z0LA 2VWMK 2W2NE 2EI6B 1HAEA 4MMZB 4X8TL 1HT5A 4JZDL 1PGEA 1J9CL 1LMJA 1WU1B 1G2MB 4PH9A 1ADXA 1A3PA 5E8DA 2OYUP 3R05A 4AQTA 2W3KB 1N1IA 1EPHA 3QH0A 2J4IB 4OTJA 2AYLA 4BDXA 1IGZA 4YZUB 2P3TA 2CJIB 4COXA 2I9BA 4Y79B 3FFGL 1PXXA 2TGFA 5JVZA 2P3UA 4Y6DB 5IKVA 2XBYL 4C16A 2P93L 1EGFA 4RUTA 2Y5GL 4CSYA 3TBDA 2Q1JB 4D0FA 5I46L 1Q4GA 2P95L 1P9JA 2EI8B 1C5MF 1CCFA 2J95B 1I0UA 2K2SB 2PUQL 2WPIE 2PHBB 4LORA 5JB9E 1NFWB 4RRZA 3BT2A 3K9XA 4YT7L 3KQEL 4CUEA 1EQHA 3CS7L 2KV4A 3N8YA 2UWPB 1IVOC 3QMOA 1PRHA 2WPKE 1IQEL 1FAKL 3TK6B 1G1TA 3NTBA 1YUFA 2W2PE 1FJSL 1NFUB 4ISIL 4BTUA 2MGRA 2Y38A 1UZPA 4BDWA 2ADXA 1JV2B 2XC4L 5COXA 3N8YB 1F0SB 3LTFB 3U7UG 5F1AA 2VVUL 1XDTR 1TOZA 1CCVA 2MGPA 1ATAA 3HPTA 3C9AC 2P94L 4RRWA 3TZIA 1KLOA 2WPHE 1M1XB 1APOA 3HS5A 2P16L 5JBCE 1IQNL 1GK5A 2VJ3A 3RR3A 4JYVL 4ZAEB 3LIWB 3N8WB 1HT8A 2DDUA 2GD4A 1EBVA 1YUGA 4RS0A 4RRXA 3N8XA 4NG9L 1NQLB 3CA7A 4ZXYL 4X8VL 1FSBA 3IITB 2M74A 1FE2A 2NPRA 1F0RB 3OLTA 1MOXC 3CENL 2WPLE 5IKQA 1EMNA 2FLRL 3V65B 1KIGL 1DVAL 1IQGL 2XBVL 3ZYIB 2BOKL 1IQIL 2XC5L 1CVUA 2P28B 4JZEL 4D0EA 4CUFA 3TGFA 1G1SA 1IQLL 3FCSB 3U73A 2BQ6A 1IQML 3M36L 1IQHL 1MQ6L 1NFXB 2W86A 1EQGA 3SOBB 1K37A 1EPIA 1FF7A 1TPGA 2EI7B 4MMXB 1G2LB 3BPSE 1PTHA 1Z6CA 3KQCL 5CKMA 1CQEA 4ZHAB 4M10A 1COUA 3N8ZA 3V64C 1OB1C 1U67A 4Z6AL 4MMYB 3KL6B 1LPKA 2YGPA 2WPME 1NT0A 1APQA 3ASIA 1XFEA 2VVVL 1JL9A 1CEJA 1MQ5L 2OYEP 2P26A 3QCWA 4O02B 2FLBL 3N8VA 3M37L 3HO5A 1W7XL 4XL1A 1LPGA 3P5BL 2VWOL 2XBXL 3FBYA 3CFWA 3GCWE 4E1GA 1HREA 1RFNB 2F9BL 3GISX 3Q3KB 1IOXA 1N7DA 2J38B 1NPEB 1XKBA 4D90A 5IKTA 3POYA 1TLEA 1CVWL 2VH0B 2Y5FL 2BOHA 1F7EA 2Y80B 3LN0A 4Z0KB 3ZYGA 3HS6A 3KK6A 1F7MA 3KRKA 4ZH8B 3KQDL 1ATDA 1LPZA 1UZJA 1YO8A 1L5GB 4RRYA 1SZBA 1L3YA 5CKQA 5JB8E 1CX2A 2PR3B 2RHPA 4A7IA 1NZIA 3KCGL 2RA0L 3HO3A 3ZYJB 2XBWL 6COXA 4Y7AB 1V3XB 4TGFA 1NFYB 2WG3C 5FDQA 2RNLA 1WHFA 1BF9A 1URKA 2VVCK 4O1ZA 1DDXA 3Q7DA 2WFXB 3LC3B 1PFXL 1EPGA 1X7AL 3HO4A 1FAXL 1FFMA 2J2UB 2BOUA 4FM5A 5JVYA 2Y7XB 1LQDA 2W2OE 2MHPA 4NA9L 1HCGB 3TK5B 1AUTL 1YUKB 5L2YL 3LTGD 2VWLL 3SW2A 3EGFA 3GCXE 4JYUL 3OLUA 1W8BL 5KN5C 3DEMA 1EAIC 2VH6B 4ISHL 1IGXA 3F1SB 2Y7ZB
chains in the Genus database with same CATH superfamily
1WHEA 1IQKL 1K36A 3IJEB 2VWNL 1ATBA 3NJPC 2JKHL 3LN1A 5CKNA 2BMGA 4Y76B 2BO2A 2P3FL 2W26B 3MQEA 1ZAQA 1EPJA 2FLGA 2BQWA 1IQJL 1IOEL 1B9WA 1UZQA 2KL7A 4LMFA 4XLWA 1IQFL 1DIYA 3MDLA 4Y7BB 3NT1A 3H5CB 1DQBA 2W2QE 3SOQA 4CUDA 2D1JB 3BT1A 1XKAL 2B7DL 1U8CB 4M11A 3LAQA 1O5DL 5CISA 2YGOA 1EMOA 1P0SL 5KIRA 2I9AA 1G1RA 2Y5HL 1IJQA 1KLJL 1Z6EL 5JBAE 3ELAL 2G00L 5F19A 4X8UL 2BOXA 1HZ8A 4BTIA 2XC0L 3LC5B 2W3IB 2WFTA 2W2ME 4Y71B 4G1MB 1KKEA 1KSNB 5IKRA 2WPJE 2FZZL 3SOVA 1YGCL 1G1QA 4YT6L 2WYJB 2WG4B 5L2ZL 1DX5I 1HJ7A 4BTTA 1UZKA 2BQ7A 2UWOB 1QFKL 3PGHA 1KLIL 4JZFL 1ATEA 2Y82B 2Y81B 3HS7A 5JW1A 3TH3L 2J94B 3N8WA 3NTGA 4XBMA 5K0HB 1EZQB 4OTYA 1HRFA 5EGMB 2P3FN 4X8SL 2H9EL 3F6UL 2HOXA 2K2TA 2UWLB 1IP0A 5JBBE 1JBUL 4BXSA 5L30L 2WYGB 4BXWA 2KB9A 4NGAL 1HAFA 3ENSA 2FD6A 2HORA 3KQBL 4ZXXL 1HX2A 2BZ6L 2J34B 1V1HA 4Z0LA 2VWMK 2W2NE 2EI6B 1HAEA 4MMZB 4X8TL 1HT5A 4JZDL 1PGEA 1J9CL 1LMJA 1WU1B 1G2MB 4PH9A 1ADXA 1A3PA 5E8DA 2OYUP 3R05A 4AQTA 2W3KB 1N1IA 1EPHA 3QH0A 2J4IB 4OTJA 2AYLA 4GU3A 1IGZA 4BDXA 4YZUB 2P3TA 2CJIB 4COXA 2I9BA 4Y79B 3FFGL 1PXXA 2TGFA 5JVZA 2P3UA 4Y6DB 1V1IA 5IKVA 2XBYL 4C16A 4A94C 2P93L 1EGFA 4RUTA 2Y5GL 4CSYA 3TBDA 2Q1JB 4D0FA 5I46L 2KNIA 1Q4GA 2P95L 1P9JA 2EI8B 1C5MF 1CCFA 2J95B 1I0UA 2K2SB 2PUQL 2WPIE 2VRSA 2PHBB 4LORA 5JB9E 1NFWB 4RRZA 3BT2A 3K9XA 4YT7L 3KQEL 4CUEA 1EQHA 3CS7L 2KV4A 3N8YA 2UWPB 1IVOC 3QMOA 1PRHA 2WPKE 1IQEL 1FAKL 3TK6B 1G1TA 3NTBA 1YUFA 2W2PE 1FJSL 1NFUB 4ISIL 4BTUA 2MGRA 2Y38A 1UZPA 4BDWA 2ADXA 1JV2B 2XC4L 5COXA 3N8YB 1F0SB 3LTFB 3U7UG 2YGQA 5F1AA 2VVUL 1XDTR 1TOZA 1CCVA 2MGPA 1ATAA 3HPTA 3C9AC 2P94L 4RRWA 3TZIA 1KLOA 1LK9A 2WPHE 2BT7A 1M1XB 1APOA 3HS5A 2P16L 5JBCE 1IQNL 1GK5A 2VJ3A 3RR3A 4JYVL 4ZAEB 3LIWB 3N8WB 1HT8A 2DDUA 2GD4A 1EBVA 1YUGA 4RS0A 4RRXA 3N8XA 4NG9L 1NQLB 3CA7A 4ZXYL 4X8VL 1FSBA 3IITB 2M74A 1FE2A 2NPRA 1F0RB 3OLTA 1MOXC 3CENL 2WPLE 5IKQA 1EMNA 2FLRL 3V65B 1KIGL 1DVAL 1IQGL 2XBVL 3ZYIB 2BOKL 1IQIL 2XC5L 1CVUA 2P28B 4JZEL 4D0EA 4CUFA 3TGFA 1G1SA 1IQLL 3FCSB 3U73A 1QIUA 2BQ6A 1IQML 3M36L 1IQHL 1MQ6L 1NFXB 2W86A 1EQGA 3SOBB 1K37A 1EPIA 1FF7A 1TPGA 2EI7B 4MMXB 1G2LB 3BPSE 1LMMA 1PTHA 1Z6CA 3KQCL 5CKMA 1CQEA 4ZHAB 4M10A 2WZPP 2JJLA 1COUA 3N8ZA 3V64C 1OB1C 1U67A 4Z6AL 4MMYB 3KL6B 1LPKA 2YGPA 2WPME 1NT0A 1APQA 3ASIA 1XFEA 4GU4A 2VVVL 1JL9A 1CEJA 1MQ5L 2OYEP 2P26A 3QCWA 4O02B 2FLBL 3N8VA 3M37L 3HO5A 2H9EC 1W7XL 4XL1A 1LPGA 3S6XA 3P5BL 2VWOL 2XBXL 3FBYA 3CFWA 3GCWE 4E1GA 1HREA 1RFNB 2F9BL 3GISX 3Q3KB 1IOXA 1N7DA 2J38B 1NPEB 1XKBA 4D90A 5IKTA 3POYA 1TLEA 1CVWL 2VH0B 2Y5FL 2BOHA 1F7EA 2Y80B 3LN0A 4Z0KB 3ZYGA 3HS6A 3KK6A 1F7MA 3KRKA 4ZH8B 3KQDL 1ATDA 1LPZA 1UZJA 1YO8A 1L5GB 4RRYA 1SZBA 1L3YA 5CKQA 5JB8E 1CX2A 2PR3B 2RHPA 4A7IA 1NZIA 3KCGL 2RA0L 3HO3A 3ZYJB 2XBWL 6COXA 4Y7AB 1V3XB 4TGFA 1NFYB 2WG3C 5FDQA 2RNLA 1WHFA 1BF9A 2BT8A 1URKA 2VVCK 4O1ZA 1DDXA 3Q7DA 2WFXB 3LC3B 2BSFA 1PFXL 1EPGA 1X7AL 3HO4A 1FAXL 1FFMA 2J2UB 2BOUA 4FM5A 5JVYA 2Y7XB 1LQDA 2W2OE 2MHPA 4NA9L 1HCGB 3TK5B 1AUTL 1YUKB 5L2YL 3LTGD 2VWLL 3SW2A 3EGFA 3GCXE 4JYUL 3OLUA 1W8BL 5KN5C 3DEMA 1EAIC 2VH6B 4ISHL 1IGXA 3F1SB 2Y7ZB
chains in the Genus database with same CATH topology
1WHEA 1IQKL 1K36A 3IJEB 2VWNL 1ATBA 3NJPC 2JKHL 3LN1A 5CKNA 2BMGA 4Y76B 2BO2A 2P3FL 2W26B 3MQEA 1ZAQA 1EPJA 2FLGA 2BQWA 1IQJL 1IOEL 1B9WA 1UZQA 2KL7A 4LMFA 4XLWA 1IQFL 1DIYA 3MDLA 4Y7BB 3NT1A 3H5CB 1DQBA 2W2QE 3SOQA 4CUDA 2D1JB 3BT1A 1XKAL 2B7DL 1U8CB 4M11A 3LAQA 1O5DL 5CISA 2YGOA 1EMOA 1P0SL 5KIRA 2I9AA 1G1RA 2Y5HL 1IJQA 1KLJL 1Z6EL 5JBAE 3ELAL 2G00L 5F19A 4X8UL 2BOXA 1HZ8A 4BTIA 2XC0L 3LC5B 2W3IB 2WFTA 2W2ME 4Y71B 4G1MB 1KSNB 5IKRA 2WPJE 2FZZL 3SOVA 1YGCL 1G1QA 4YT6L 2WYJB 2WG4B 5L2ZL 1DX5I 1HJ7A 4BTTA 1UZKA 2BQ7A 2UWOB 1QFKL 3PGHA 1KLIL 4JZFL 1ATEA 2Y82B 2Y81B 3HS7A 5JW1A 3TH3L 2J94B 3N8WA 3NTGA 4XBMA 5K0HB 1EZQB 4OTYA 1HRFA 5EGMB 2P3FN 4X8SL 2H9EL 3F6UL 2K2TA 2UWLB 1IP0A 5JBBE 1JBUL 4BXSA 5L30L 2WYGB 4BXWA 2KB9A 4NGAL 1HAFA 3ENSA 2FD6A 3KQBL 4ZXXL 1HX2A 2BZ6L 2J34B 4Z0LA 2VWMK 2W2NE 2EI6B 1HAEA 4MMZB 4X8TL 1HT5A 4JZDL 1PGEA 1J9CL 1LMJA 1WU1B 1G2MB 4PH9A 1ADXA 1A3PA 5E8DA 2OYUP 3R05A 4AQTA 2W3KB 1N1IA 1EPHA 3QH0A 2J4IB 4OTJA 2AYLA 4BDXA 1IGZA 4YZUB 2P3TA 2CJIB 4COXA 2I9BA 4Y79B 3FFGL 1PXXA 2TGFA 5JVZA 2P3UA 4Y6DB 5IKVA 2XBYL 4C16A 4A94C 2P93L 1EGFA 4RUTA 2Y5GL 4CSYA 3TBDA 2Q1JB 4D0FA 5I46L 2KNIA 1Q4GA 2P95L 1P9JA 2EI8B 1C5MF 1CCFA 2J95B 1I0UA 2K2SB 2PUQL 2WPIE 2PHBB 4LORA 5JB9E 1NFWB 4RRZA 3BT2A 3K9XA 4YT7L 3KQEL 4CUEA 1EQHA 3CS7L 2KV4A 3N8YA 2UWPB 1IVOC 3QMOA 1PRHA 2WPKE 1IQEL 1FAKL 3TK6B 1G1TA 3NTBA 1YUFA 2W2PE 1FJSL 1NFUB 4ISIL 4BTUA 2MGRA 2Y38A 1UZPA 4BDWA 2ADXA 1JV2B 2XC4L 5COXA 3N8YB 1F0SB 3LTFB 3U7UG 2YGQA 5F1AA 2VVUL 1XDTR 1TOZA 1CCVA 2MGPA 1ATAA 3HPTA 3C9AC 2P94L 4RRWA 3TZIA 1KLOA 2WPHE 1M1XB 1APOA 3HS5A 2P16L 5JBCE 1IQNL 1GK5A 2VJ3A 3RR3A 4JYVL 4ZAEB 3LIWB 3N8WB 1HT8A 2DDUA 2GD4A 1EBVA 1YUGA 4RS0A 4RRXA 3N8XA 4NG9L 1NQLB 3CA7A 4ZXYL 4X8VL 1FSBA 3IITB 2M74A 1FE2A 2NPRA 1F0RB 3OLTA 1MOXC 3CENL 2WPLE 5IKQA 1EMNA 2FLRL 3V65B 1KIGL 1DVAL 1IQGL 2XBVL 3ZYIB 2BOKL 1IQIL 2XC5L 1CVUA 2P28B 4JZEL 4D0EA 4CUFA 3TGFA 1G1SA 1IQLL 3FCSB 3U73A 2BQ6A 1IQML 3M36L 1IQHL 1MQ6L 1NFXB 2W86A 1EQGA 3SOBB 1K37A 1EPIA 1FF7A 1TPGA 2EI7B 4MMXB 1G2LB 3BPSE 1LMMA 1PTHA 1Z6CA 3KQCL 5CKMA 1CQEA 4ZHAB 4M10A 2WZPP 1COUA 3N8ZA 3V64C 1OB1C 1U67A 4Z6AL 4MMYB 3KL6B 1LPKA 2YGPA 2WPME 1NT0A 1APQA 3ASIA 1XFEA 2VVVL 1JL9A 1CEJA 1MQ5L 2OYEP 2P26A 3QCWA 4O02B 2FLBL 3N8VA 3M37L 3HO5A 2H9EC 1W7XL 4XL1A 1LPGA 3S6XA 3P5BL 2VWOL 2XBXL 3FBYA 3CFWA 3GCWE 4E1GA 1HREA 1RFNB 2F9BL 3GISX 3Q3KB 1IOXA 1N7DA 2J38B 1NPEB 1XKBA 4D90A 5IKTA 3POYA 1TLEA 1CVWL 2VH0B 2Y5FL 2BOHA 1F7EA 2Y80B 3LN0A 4Z0KB 3ZYGA 3HS6A 3KK6A 1F7MA 3KRKA 4ZH8B 3KQDL 1ATDA 1LPZA 1UZJA 1YO8A 1L5GB 4RRYA 1SZBA 1L3YA 5CKQA 5JB8E 1CX2A 2PR3B 2RHPA 4A7IA 1NZIA 3KCGL 2RA0L 3HO3A 3ZYJB 2XBWL 6COXA 4Y7AB 1V3XB 4TGFA 1NFYB 2WG3C 5FDQA 2RNLA 1WHFA 1BF9A 1URKA 2VVCK 4O1ZA 1DDXA 3Q7DA 2WFXB 3LC3B 1PFXL 1EPGA 1X7AL 3HO4A 1FAXL 1FFMA 2J2UB 2BOUA 4FM5A 5JVYA 2Y7XB 1LQDA 2W2OE 2MHPA 4NA9L 1HCGB 3TK5B 1AUTL 1YUKB 5L2YL 3LTGD 2VWLL 3SW2A 3EGFA 3GCXE 4JYUL 3OLUA 1W8BL 5KN5C 3DEMA 1EAIC 2VH6B 4ISHL 1IGXA 3F1SB 2Y7ZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WHE A;  1IQK L;  1K36 A;  3IJE B;  2VWN L;  1ATB A;  3NJP C;  2JKH L;  3LN1 A;  5CKN A;  2BMG A;  4Y76 B;  2BO2 A;  2P3F L;  2W26 B;  3MQE A;  1ZAQ A;  1EPJ A;  2FLG A;  2BQW A;  1IQJ L;  1IOE L;  1B9W A;  1UZQ A;  2KL7 A;  4LMF A;  4XLW A;  1IQF L;  1DIY A;  3MDL A;  4Y7B B;  3NT1 A;  3H5C B;  1DQB A;  2W2Q E;  3SOQ A;  4CUD A;  2D1J B;  3BT1 A;  1XKA L;  2B7D L;  1U8C B;  4M11 A;  3LAQ A;  1O5D L;  5CIS A;  2YGO A;  1EMO A;  1P0S L;  5KIR A;  2I9A A;  1G1R A;  2Y5H L;  1IJQ A;  1KLJ L;  1Z6E L;  5JBA E;  3ELA L;  2G00 L;  5F19 A;  4X8U L;  2BOX A;  1HZ8 A;  4BTI A;  2XC0 L;  3LC5 B;  2W3I B;  2WFT A;  2W2M E;  4Y71 B;  4G1M B;  1KSN B;  5IKR A;  2WPJ E;  2FZZ L;  3SOV A;  1YGC L;  1G1Q A;  4YT6 L;  2WYJ B;  2WG4 B;  5L2Z L;  1DX5 I;  1HJ7 A;  4BTT A;  1UZK A;  2BQ7 A;  2UWO B;  1QFK L;  3PGH A;  1KLI L;  4JZF L;  1ATE A;  2Y82 B;  2Y81 B;  3HS7 A;  5JW1 A;  3TH3 L;  2J94 B;  3N8W A;  3NTG A;  4XBM A;  5K0H B;  1EZQ B;  4OTY A;  1HRF A;  5EGM B;  2P3F N;  4X8S L;  2H9E L;  3F6U L;  2K2T A;  2UWL B;  1IP0 A;  5JBB E;  1JBU L;  4BXS A;  5L30 L;  2WYG B;  4BXW A;  2KB9 A;  4NGA L;  1HAF A;  3ENS A;  2FD6 A;  3KQB L;  4ZXX L;  1HX2 A;  2BZ6 L;  2J34 B;  4Z0L A;  2VWM K;  2W2N E;  2EI6 B;  1HAE A;  4MMZ B;  4X8T L;  1HT5 A;  4JZD L;  1PGE A;  1J9C L;  1LMJ A;  1WU1 B;  1G2M B;  4PH9 A;  1ADX A;  1A3P A;  5E8D A;  2OYU P;  3R05 A;  4AQT A;  2W3K B;  1N1I A;  1EPH A;  3QH0 A;  2J4I B;  4OTJ A;  2AYL A;  4BDX A;  1IGZ A;  4YZU B;  2P3T A;  2CJI B;  4COX A;  2I9B A;  4Y79 B;  3FFG L;  1PXX A;  2TGF A;  5JVZ A;  2P3U A;  4Y6D B;  5IKV A;  2XBY L;  4C16 A;  2P93 L;  1EGF A;  4RUT A;  2Y5G L;  4CSY A;  3TBD A;  2Q1J B;  4D0F A;  5I46 L;  1Q4G A;  2P95 L;  1P9J A;  2EI8 B;  1C5M F;  1CCF A;  2J95 B;  1I0U A;  2K2S B;  2PUQ L;  2WPI E;  2PHB B;  4LOR A;  5JB9 E;  1NFW B;  4RRZ A;  3BT2 A;  3K9X A;  4YT7 L;  3KQE L;  4CUE A;  1EQH A;  3CS7 L;  2KV4 A;  3N8Y A;  2UWP B;  1IVO C;  3QMO A;  1PRH A;  2WPK E;  1IQE L;  1FAK L;  3TK6 B;  1G1T A;  3NTB A;  1YUF A;  2W2P E;  1FJS L;  1NFU B;  4ISI L;  4BTU A;  2MGR A;  2Y38 A;  1UZP A;  4BDW A;  2ADX A;  1JV2 B;  2XC4 L;  5COX A;  3N8Y B;  1F0S B;  3LTF B;  3U7U G;  5F1A A;  2VVU L;  1XDT R;  1TOZ A;  1CCV A;  2MGP A;  1ATA A;  3HPT A;  3C9A C;  2P94 L;  4RRW A;  3TZI A;  1KLO A;  2WPH E;  1M1X B;  1APO A;  3HS5 A;  2P16 L;  5JBC E;  1IQN L;  1GK5 A;  2VJ3 A;  3RR3 A;  4JYV L;  4ZAE B;  3LIW B;  3N8W B;  1HT8 A;  2DDU A;  2GD4 A;  1EBV A;  1YUG A;  4RS0 A;  4RRX A;  3N8X A;  4NG9 L;  1NQL B;  3CA7 A;  4ZXY L;  4X8V L;  1FSB A;  3IIT B;  2M74 A;  1FE2 A;  2NPR A;  1F0R B;  3OLT A;  1MOX C;  3CEN L;  2WPL E;  5IKQ A;  1EMN A;  2FLR L;  3V65 B;  1KIG L;  1DVA L;  1IQG L;  2XBV L;  3ZYI B;  2BOK L;  1IQI L;  2XC5 L;  1CVU A;  2P28 B;  4JZE L;  4D0E A;  4CUF A;  3TGF A;  1G1S A;  1IQL L;  3FCS B;  3U73 A;  2BQ6 A;  1IQM L;  3M36 L;  1IQH L;  1MQ6 L;  1NFX B;  2W86 A;  1EQG A;  3SOB B;  1K37 A;  1EPI A;  1FF7 A;  1TPG A;  2EI7 B;  4MMX B;  1G2L B;  3BPS E;  1PTH A;  1Z6C A;  3KQC L;  5CKM A;  1CQE A;  4ZHA B;  4M10 A;  1COU A;  3N8Z A;  3V64 C;  1OB1 C;  1U67 A;  4Z6A L;  4MMY B;  3KL6 B;  1LPK A;  2YGP A;  2WPM E;  1NT0 A;  1APQ A;  3ASI A;  1XFE A;  2VVV L;  1JL9 A;  1CEJ A;  1MQ5 L;  2OYE P;  2P26 A;  3QCW A;  4O02 B;  2FLB L;  3N8V A;  3M37 L;  3HO5 A;  1W7X L;  4XL1 A;  1LPG A;  3P5B L;  2VWO L;  2XBX L;  3FBY A;  3CFW A;  3GCW E;  4E1G A;  1HRE A;  1RFN B;  2F9B L;  3GIS X;  3Q3K B;  1IOX A;  1N7D A;  2J38 B;  1NPE B;  1XKB A;  4D90 A;  5IKT A;  3POY A;  1TLE A;  1CVW L;  2VH0 B;  2Y5F L;  2BOH A;  1F7E A;  2Y80 B;  3LN0 A;  4Z0K B;  3ZYG A;  3HS6 A;  3KK6 A;  1F7M A;  3KRK A;  4ZH8 B;  3KQD L;  1ATD A;  1LPZ A;  1UZJ A;  1YO8 A;  1L5G B;  4RRY A;  1SZB A;  1L3Y A;  5CKQ A;  5JB8 E;  1CX2 A;  2PR3 B;  2RHP A;  4A7I A;  1NZI A;  3KCG L;  2RA0 L;  3HO3 A;  3ZYJ B;  2XBW L;  6COX A;  4Y7A B;  1V3X B;  4TGF A;  1NFY B;  2WG3 C;  5FDQ A;  2RNL A;  1WHF A;  1BF9 A;  1URK A;  2VVC K;  4O1Z A;  1DDX A;  3Q7D A;  2WFX B;  3LC3 B;  1PFX L;  1EPG A;  1X7A L;  3HO4 A;  1FAX L;  1FFM A;  2J2U B;  2BOU A;  4FM5 A;  5JVY A;  2Y7X B;  1LQD A;  2W2O E;  2MHP A;  4NA9 L;  1HCG B;  3TK5 B;  1AUT L;  1YUK B;  5L2Y L;  3LTG D;  2VWL L;  3SW2 A;  3EGF A;  3GCX E;  4JYU L;  3OLU A;  1W8B L;  5KN5 C;  3DEM A;  1EAI C;  2VH6 B;  4ISH L;  1IGX A;  3F1S B;  2Y7Z B; 
#chains in the Genus database with same CATH topology
 1WHE A;  1IQK L;  1K36 A;  3IJE B;  2VWN L;  1ATB A;  3NJP C;  2JKH L;  3LN1 A;  5CKN A;  2BMG A;  4Y76 B;  2BO2 A;  2P3F L;  2W26 B;  3MQE A;  1ZAQ A;  1EPJ A;  2FLG A;  2BQW A;  1IQJ L;  1IOE L;  1B9W A;  1UZQ A;  2KL7 A;  4LMF A;  4XLW A;  1IQF L;  1DIY A;  3MDL A;  4Y7B B;  3NT1 A;  3H5C B;  1DQB A;  2W2Q E;  3SOQ A;  4CUD A;  2D1J B;  3BT1 A;  1XKA L;  2B7D L;  1U8C B;  4M11 A;  3LAQ A;  1O5D L;  5CIS A;  2YGO A;  1EMO A;  1P0S L;  5KIR A;  2I9A A;  1G1R A;  2Y5H L;  1IJQ A;  1KLJ L;  1Z6E L;  5JBA E;  3ELA L;  2G00 L;  5F19 A;  4X8U L;  2BOX A;  1HZ8 A;  4BTI A;  2XC0 L;  3LC5 B;  2W3I B;  2WFT A;  2W2M E;  4Y71 B;  4G1M B;  1KKE A;  1KSN B;  5IKR A;  2WPJ E;  2FZZ L;  3SOV A;  1YGC L;  1G1Q A;  4YT6 L;  2WYJ B;  2WG4 B;  5L2Z L;  1DX5 I;  1HJ7 A;  4BTT A;  1UZK A;  2BQ7 A;  2UWO B;  1QFK L;  3PGH A;  1KLI L;  4JZF L;  1ATE A;  2Y82 B;  2Y81 B;  3HS7 A;  5JW1 A;  3TH3 L;  2J94 B;  3N8W A;  3NTG A;  4XBM A;  5K0H B;  1EZQ B;  4OTY A;  1HRF A;  5EGM B;  2P3F N;  4X8S L;  2H9E L;  3F6U L;  2HOX A;  2K2T A;  2UWL B;  1IP0 A;  5JBB E;  1JBU L;  4BXS A;  5L30 L;  2WYG B;  4BXW A;  2KB9 A;  4NGA L;  1HAF A;  3ENS A;  2FD6 A;  2HOR A;  3KQB L;  4ZXX L;  1HX2 A;  2BZ6 L;  2J34 B;  1V1H A;  4Z0L A;  2VWM K;  2W2N E;  2EI6 B;  1HAE A;  4MMZ B;  4X8T L;  1HT5 A;  4JZD L;  1PGE A;  1J9C L;  1LMJ A;  1WU1 B;  1G2M B;  4PH9 A;  1ADX A;  1A3P A;  5E8D A;  2OYU P;  3R05 A;  4AQT A;  2W3K B;  1N1I A;  1EPH A;  3QH0 A;  2J4I B;  4OTJ A;  2AYL A;  4GU3 A;  1IGZ A;  4BDX A;  4YZU B;  2P3T A;  2CJI B;  4COX A;  2I9B A;  4Y79 B;  3FFG L;  1PXX A;  2TGF A;  5JVZ A;  2P3U A;  4Y6D B;  1V1I A;  5IKV A;  2XBY L;  4C16 A;  4A94 C;  2P93 L;  1EGF A;  4RUT A;  2Y5G L;  4CSY A;  3TBD A;  2Q1J B;  4D0F A;  5I46 L;  2KNI A;  1Q4G A;  2P95 L;  1P9J A;  2EI8 B;  1C5M F;  1CCF A;  2J95 B;  1I0U A;  2K2S B;  2PUQ L;  2WPI E;  2VRS A;  2PHB B;  4LOR A;  5JB9 E;  1NFW B;  4RRZ A;  3BT2 A;  3K9X A;  4YT7 L;  3KQE L;  4CUE A;  1EQH A;  3CS7 L;  2KV4 A;  3N8Y A;  2UWP B;  1IVO C;  3QMO A;  1PRH A;  2WPK E;  1IQE L;  1FAK L;  3TK6 B;  1G1T A;  3NTB A;  1YUF A;  2W2P E;  1FJS L;  1NFU B;  4ISI L;  4BTU A;  2MGR A;  2Y38 A;  1UZP A;  4BDW A;  2ADX A;  1JV2 B;  2XC4 L;  5COX A;  3N8Y B;  1F0S B;  3LTF B;  3U7U G;  2YGQ A;  5F1A A;  2VVU L;  1XDT R;  1TOZ A;  1CCV A;  2MGP A;  1ATA A;  3HPT A;  3C9A C;  2P94 L;  4RRW A;  3TZI A;  1KLO A;  1LK9 A;  2WPH E;  2BT7 A;  1M1X B;  1APO A;  3HS5 A;  2P16 L;  5JBC E;  1IQN L;  1GK5 A;  2VJ3 A;  3RR3 A;  4JYV L;  4ZAE B;  3LIW B;  3N8W B;  1HT8 A;  2DDU A;  2GD4 A;  1EBV A;  1YUG A;  4RS0 A;  4RRX A;  3N8X A;  4NG9 L;  1NQL B;  3CA7 A;  4ZXY L;  4X8V L;  1FSB A;  3IIT B;  2M74 A;  1FE2 A;  2NPR A;  1F0R B;  3OLT A;  1MOX C;  3CEN L;  2WPL E;  5IKQ A;  1EMN A;  2FLR L;  3V65 B;  1KIG L;  1DVA L;  1IQG L;  2XBV L;  3ZYI B;  2BOK L;  1IQI L;  2XC5 L;  1CVU A;  2P28 B;  4JZE L;  4D0E A;  4CUF A;  3TGF A;  1G1S A;  1IQL L;  3FCS B;  3U73 A;  1QIU A;  2BQ6 A;  1IQM L;  3M36 L;  1IQH L;  1MQ6 L;  1NFX B;  2W86 A;  1EQG A;  3SOB B;  1K37 A;  1EPI A;  1FF7 A;  1TPG A;  2EI7 B;  4MMX B;  1G2L B;  3BPS E;  1LMM A;  1PTH A;  1Z6C A;  3KQC L;  5CKM A;  1CQE A;  4ZHA B;  4M10 A;  2WZP P;  2JJL A;  1COU A;  3N8Z A;  3V64 C;  1OB1 C;  1U67 A;  4Z6A L;  4MMY B;  3KL6 B;  1LPK A;  2YGP A;  2WPM E;  1NT0 A;  1APQ A;  3ASI A;  1XFE A;  4GU4 A;  2VVV L;  1JL9 A;  1CEJ A;  1MQ5 L;  2OYE P;  2P26 A;  3QCW A;  4O02 B;  2FLB L;  3N8V A;  3M37 L;  3HO5 A;  2H9E C;  1W7X L;  4XL1 A;  1LPG A;  3S6X A;  3P5B L;  2VWO L;  2XBX L;  3FBY A;  3CFW A;  3GCW E;  4E1G A;  1HRE A;  1RFN B;  2F9B L;  3GIS X;  3Q3K B;  1IOX A;  1N7D A;  2J38 B;  1NPE B;  1XKB A;  4D90 A;  5IKT A;  3POY A;  1TLE A;  1CVW L;  2VH0 B;  2Y5F L;  2BOH A;  1F7E A;  2Y80 B;  3LN0 A;  4Z0K B;  3ZYG A;  3HS6 A;  3KK6 A;  1F7M A;  3KRK A;  4ZH8 B;  3KQD L;  1ATD A;  1LPZ A;  1UZJ A;  1YO8 A;  1L5G B;  4RRY A;  1SZB A;  1L3Y A;  5CKQ A;  5JB8 E;  1CX2 A;  2PR3 B;  2RHP A;  4A7I A;  1NZI A;  3KCG L;  2RA0 L;  3HO3 A;  3ZYJ B;  2XBW L;  6COX A;  4Y7A B;  1V3X B;  4TGF A;  1NFY B;  2WG3 C;  5FDQ A;  2RNL A;  1WHF A;  1BF9 A;  2BT8 A;  1URK A;  2VVC K;  4O1Z A;  1DDX A;  3Q7D A;  2WFX B;  3LC3 B;  2BSF A;  1PFX L;  1EPG A;  1X7A L;  3HO4 A;  1FAX L;  1FFM A;  2J2U B;  2BOU A;  4FM5 A;  5JVY A;  2Y7X B;  1LQD A;  2W2O E;  2MHP A;  4NA9 L;  1HCG B;  3TK5 B;  1AUT L;  1YUK B;  5L2Y L;  3LTG D;  2VWL L;  3SW2 A;  3EGF A;  3GCX E;  4JYU L;  3OLU A;  1W8B L;  5KN5 C;  3DEM A;  1EAI C;  2VH6 B;  4ISH L;  1IGX A;  3F1S B;  2Y7Z B; 
#chains in the Genus database with same CATH homology
 1WHE A;  1IQK L;  1K36 A;  3IJE B;  2VWN L;  1ATB A;  3NJP C;  2JKH L;  3LN1 A;  5CKN A;  2BMG A;  4Y76 B;  2BO2 A;  2P3F L;  2W26 B;  3MQE A;  1ZAQ A;  1EPJ A;  2FLG A;  2BQW A;  1IQJ L;  1IOE L;  1B9W A;  1UZQ A;  2KL7 A;  4LMF A;  4XLW A;  1IQF L;  1DIY A;  3MDL A;  4Y7B B;  3NT1 A;  3H5C B;  1DQB A;  2W2Q E;  3SOQ A;  4CUD A;  2D1J B;  3BT1 A;  1XKA L;  2B7D L;  1U8C B;  4M11 A;  3LAQ A;  1O5D L;  5CIS A;  2YGO A;  1EMO A;  1P0S L;  5KIR A;  2I9A A;  1G1R A;  2Y5H L;  1IJQ A;  1KLJ L;  1Z6E L;  5JBA E;  3ELA L;  2G00 L;  5F19 A;  4X8U L;  2BOX A;  1HZ8 A;  4BTI A;  2XC0 L;  3LC5 B;  2W3I B;  2WFT A;  2W2M E;  4Y71 B;  4G1M B;  1KSN B;  5IKR A;  2WPJ E;  2FZZ L;  3SOV A;  1YGC L;  1G1Q A;  4YT6 L;  2WYJ B;  2WG4 B;  5L2Z L;  1DX5 I;  1HJ7 A;  4BTT A;  1UZK A;  2BQ7 A;  2UWO B;  1QFK L;  3PGH A;  1KLI L;  4JZF L;  1ATE A;  2Y82 B;  2Y81 B;  3HS7 A;  5JW1 A;  3TH3 L;  2J94 B;  3N8W A;  3NTG A;  4XBM A;  5K0H B;  1EZQ B;  4OTY A;  1HRF A;  5EGM B;  2P3F N;  4X8S L;  2H9E L;  3F6U L;  2K2T A;  2UWL B;  1IP0 A;  5JBB E;  1JBU L;  4BXS A;  5L30 L;  2WYG B;  4BXW A;  2KB9 A;  4NGA L;  1HAF A;  3ENS A;  2FD6 A;  3KQB L;  4ZXX L;  1HX2 A;  2BZ6 L;  2J34 B;  4Z0L A;  2VWM K;  2W2N E;  2EI6 B;  1HAE A;  4MMZ B;  4X8T L;  1HT5 A;  4JZD L;  1PGE A;  1J9C L;  1LMJ A;  1WU1 B;  1G2M B;  4PH9 A;  1ADX A;  1A3P A;  5E8D A;  2OYU P;  3R05 A;  4AQT A;  2W3K B;  1N1I A;  1EPH A;  3QH0 A;  2J4I B;  4OTJ A;  2AYL A;  4BDX A;  1IGZ A;  4YZU B;  2P3T A;  2CJI B;  4COX A;  2I9B A;  4Y79 B;  3FFG L;  1PXX A;  2TGF A;  5JVZ A;  2P3U A;  4Y6D B;  5IKV A;  2XBY L;  4C16 A;  4A94 C;  2P93 L;  1EGF A;  4RUT A;  2Y5G L;  4CSY A;  3TBD A;  2Q1J B;  4D0F A;  5I46 L;  2KNI A;  1Q4G A;  2P95 L;  1P9J A;  2EI8 B;  1C5M F;  1CCF A;  2J95 B;  1I0U A;  2K2S B;  2PUQ L;  2WPI E;  2PHB B;  4LOR A;  5JB9 E;  1NFW B;  4RRZ A;  3BT2 A;  3K9X A;  4YT7 L;  3KQE L;  4CUE A;  1EQH A;  3CS7 L;  2KV4 A;  3N8Y A;  2UWP B;  1IVO C;  3QMO A;  1PRH A;  2WPK E;  1IQE L;  1FAK L;  3TK6 B;  1G1T A;  3NTB A;  1YUF A;  2W2P E;  1FJS L;  1NFU B;  4ISI L;  4BTU A;  2MGR A;  2Y38 A;  1UZP A;  4BDW A;  2ADX A;  1JV2 B;  2XC4 L;  5COX A;  3N8Y B;  1F0S B;  3LTF B;  3U7U G;  2YGQ A;  5F1A A;  2VVU L;  1XDT R;  1TOZ A;  1CCV A;  2MGP A;  1ATA A;  3HPT A;  3C9A C;  2P94 L;  4RRW A;  3TZI A;  1KLO A;  2WPH E;  1M1X B;  1APO A;  3HS5 A;  2P16 L;  5JBC E;  1IQN L;  1GK5 A;  2VJ3 A;  3RR3 A;  4JYV L;  4ZAE B;  3LIW B;  3N8W B;  1HT8 A;  2DDU A;  2GD4 A;  1EBV A;  1YUG A;  4RS0 A;  4RRX A;  3N8X A;  4NG9 L;  1NQL B;  3CA7 A;  4ZXY L;  4X8V L;  1FSB A;  3IIT B;  2M74 A;  1FE2 A;  2NPR A;  1F0R B;  3OLT A;  1MOX C;  3CEN L;  2WPL E;  5IKQ A;  1EMN A;  2FLR L;  3V65 B;  1KIG L;  1DVA L;  1IQG L;  2XBV L;  3ZYI B;  2BOK L;  1IQI L;  2XC5 L;  1CVU A;  2P28 B;  4JZE L;  4D0E A;  4CUF A;  3TGF A;  1G1S A;  1IQL L;  3FCS B;  3U73 A;  2BQ6 A;  1IQM L;  3M36 L;  1IQH L;  1MQ6 L;  1NFX B;  2W86 A;  1EQG A;  3SOB B;  1K37 A;  1EPI A;  1FF7 A;  1TPG A;  2EI7 B;  4MMX B;  1G2L B;  3BPS E;  1LMM A;  1PTH A;  1Z6C A;  3KQC L;  5CKM A;  1CQE A;  4ZHA B;  4M10 A;  2WZP P;  1COU A;  3N8Z A;  3V64 C;  1OB1 C;  1U67 A;  4Z6A L;  4MMY B;  3KL6 B;  1LPK A;  2YGP A;  2WPM E;  1NT0 A;  1APQ A;  3ASI A;  1XFE A;  2VVV L;  1JL9 A;  1CEJ A;  1MQ5 L;  2OYE P;  2P26 A;  3QCW A;  4O02 B;  2FLB L;  3N8V A;  3M37 L;  3HO5 A;  2H9E C;  1W7X L;  4XL1 A;  1LPG A;  3S6X A;  3P5B L;  2VWO L;  2XBX L;  3FBY A;  3CFW A;  3GCW E;  4E1G A;  1HRE A;  1RFN B;  2F9B L;  3GIS X;  3Q3K B;  1IOX A;  1N7D A;  2J38 B;  1NPE B;  1XKB A;  4D90 A;  5IKT A;  3POY A;  1TLE A;  1CVW L;  2VH0 B;  2Y5F L;  2BOH A;  1F7E A;  2Y80 B;  3LN0 A;  4Z0K B;  3ZYG A;  3HS6 A;  3KK6 A;  1F7M A;  3KRK A;  4ZH8 B;  3KQD L;  1ATD A;  1LPZ A;  1UZJ A;  1YO8 A;  1L5G B;  4RRY A;  1SZB A;  1L3Y A;  5CKQ A;  5JB8 E;  1CX2 A;  2PR3 B;  2RHP A;  4A7I A;  1NZI A;  3KCG L;  2RA0 L;  3HO3 A;  3ZYJ B;  2XBW L;  6COX A;  4Y7A B;  1V3X B;  4TGF A;  1NFY B;  2WG3 C;  5FDQ A;  2RNL A;  1WHF A;  1BF9 A;  1URK A;  2VVC K;  4O1Z A;  1DDX A;  3Q7D A;  2WFX B;  3LC3 B;  1PFX L;  1EPG A;  1X7A L;  3HO4 A;  1FAX L;  1FFM A;  2J2U B;  2BOU A;  4FM5 A;  5JVY A;  2Y7X B;  1LQD A;  2W2O E;  2MHP A;  4NA9 L;  1HCG B;  3TK5 B;  1AUT L;  1YUK B;  5L2Y L;  3LTG D;  2VWL L;  3SW2 A;  3EGF A;  3GCX E;  4JYU L;  3OLU A;  1W8B L;  5KN5 C;  3DEM A;  1EAI C;  2VH6 B;  4ISH L;  1IGX A;  3F1S B;  2Y7Z B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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