4A7IA

Factor xa in complex with a potent 2-amino-ethane sulfonamide inhibitor
Total Genus 11
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
53
structure length
53
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Fragment Deconstruction of Small, Potent Factor Xa Inhibitors: Exploring the Superadditivity Energetics of Fragment Linking in Protein-Ligand Complexes.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords FACTOR X LIGHT CHAIN
total genus 11
structure length 53
sequence length 53
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2011-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00008 EGF EGF-like domain
A PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 4a7iA00
3KQCL 3HO5A 2WPME 2OYUP 3N8VA 3R05A 1Z6EL 2F9BL 3IJEB 3ENSA 2BOUA 2BQWA 1BF9A 1N7DA 3SOVA 3HO4A 3NTGA 4Y76B 5IKQA 3LTFB 4D90A 1UZJA 3PGHA 2FLGA 1EMOA 2EI6B 5KN5C 4COXA 4Z0LA 1CCFA 3HS6A 3M37L 5COXA 4RRXA 1P0SL 2NPRA 3KRKA 1OB1C 2W2PE 2BOKL 1W8BL 4XLWA 4Y7AB 4CUDA 2H9EL 1RFNB 2W3IB 1HAEA 1CVWL 5JW1A 1WU1B 1IP0A 5IKRA 2VWOL 1I0UA 1DX5I 2BQ6A 1IGZA 3TBDA 1EGFA 2CJIB 1FF7A 1UZQA 1IOXA 2VJ3A 1YUKB 5IKVA 3F1SB 1HRFA 1MOXC 5CISA 2Y81B 3U7UG 3F6UL 1WHFA 3U73A 1DQBA 3OLUA 1KIGL 1NFXB 4JYVL 1LPKA 2J94B 1EQGA 3H5CB 1CEJA 2RHPA 2P26A 5E8DA 4RUTA 1V3XB 1JV2B 1NQLB 4JZFL 3DEMA 1NFYB 1ATEA 1IGXA 3N8ZA 1JL9A 4X8TL 1CCVA 1COUA 1IQLL 1URKA 3TK6B 2MHPA 4ISHL 4ZHAB 5IKTA 4ISIL 4M11A 5FDQA 1FFMA 1X7AL 3KQDL 3N8WB 4D0EA 3KK6A 3KQBL 1IQFL 1HZ8A 3MQEA 1EQHA 1F7EA 4YZUB 1FJSL 1EPJA 1L3YA 1G1QA 1IOEL 2W86A 4ZAEB 2XC4L 1W7XL 1CVUA 4ZH8B 3V65B 2J4IB 3BT1A 1C5MF 2W3KB 4D0FA 1YO8A 1XKAL 2P94L 1ADXA 1F0SB 1TLEA 3IITB 2XBYL 5JVZA 5I46L 2KB9A 4XBMA 3GISX 5CKQA 2WPJE 3ZYJB 1ATDA 1G1RA 5JVYA 5JBBE 1AUTL 1IQIL 2Y38A 1GK5A 3CENL 4YT6L 2WFXB 1Q4GA 2J38B 1O5DL 3LC5B 4MMYB 3ZYIB 2WYGB 2Y5HL 2P3TA 4ZXYL 1F7MA 3TGFA 1PFXL 2P95L 3GCXE 3CFWA 3MDLA 1WHEA 1HCGB 2P93L 2ADXA 4BXSA 2VH0B 4OTJA 4CSYA 3OLTA 1IQNL 6COXA 4O02B 3NT1A 4Y7BB 1M1XB 1IQKL 1U8CB 4ZXXL 3NTBA 2Y82B 4RRZA 3V64C 4NG9L 4XL1A 4JZEL 2Y5FL 2BQ7A 1EBVA 1MQ6L 1XDTR 2J34B 4CUFA 1EAIC 2I9BA 2MGPA 4NA9L 1ATBA 2FLBL 3TH3L 4M10A 3N8WA 2G00L 1F0RB 4BTIA 1IQHL 1K36A 4MMXB 1DDXA 4X8VL 1HAFA 2XBXL 3N8YA 2KL7A 4O1ZA 3QH0A 2MGRA 5L30L 2WYJB 2XC0L 1J9CL 1TOZA 3ELAL 1YUGA 2WPIE 3BPSE 3QMOA 3FBYA 2XC5L 1NPEB 1PGEA 3POYA 2JKHL 2WPHE 1NZIA 2EI7B 1EZQB 3LAQA 2Y80B 3FFGL 1Z6CA 1ATAA 1CQEA 4Y6DB 2PR3B 2W2ME 1IJQA 2XBWL 2P3UA 4E1GA 2I9AA 3LIWB 3N8YB 2AYLA 3HO3A 2WG3C 5JBAE 2YGPA 5L2ZL 2WPLE 1HX2A 2Y7ZB 2BOXA 4Z0KB 1HT8A 4LORA 3FCSB 1B9WA 3ASIA 4OTYA 3LTGD 2XBVL 3NJPC 1XKBA 4PH9A 4C16A 2FD6A 5F19A 5CKNA 1FE2A 4BDWA 3M36L 1LPGA 1SZBA 1A3PA 4A7IA 1G1SA 1MQ5L 1EMNA 2B7DL 2M74A 2D1JB 1NFUB 2RNLA 4G1MB 3CS7L 1DIYA 4FM5A 4BTUA 1APQA 2W26B 4X8UL 2W2QE 1EPIA 2KV4A 2VVUL 3ZYGA 2Y5GL 1NFWB 5EGMB 1P9JA 1PXXA 3KQEL 1JBUL 1QFKL 3RR3A 1G2LB 2UWOB 1LQDA 4RRYA 1NT0A 4Y79B 1HJ7A 3HS5A 4CUEA 2GD4A 5F1AA 2RA0L 2OYEP 2VWNL 2W2NE 3BT2A 1FAXL 4X8SL 1IQML 2VH6B 3CA7A 2K2TA 1KLOA 4RRWA 2VWLL 1YGCL 3Q7DA 1PRHA 2J2UB 2P28B 2BO2A 4YT7L 1G2MB 3LC3B 3P5BL 1CX2A 3HS7A 1KLJL 2P16L 4BTTA 1FSBA 1TPGA 2PHBB 1K37A 1KLIL 1EPHA 1UZPA 5L2YL 3GCWE 1XFEA 1YUFA 2J95B 5JB9E 2W2OE 2BZ6L 2Y7XB 2P3FL 1IVOC 1PTHA 2EI8B 3SOBB 4BXWA 5KIRA 3TK5B 5JB8E 1APOA 1IQEL 3QCWA 4LMFA 1KSNB 1IQGL 4JYUL 5CKMA 4Y71B 2P3FN 2UWPB 3KCGL 3LN0A 2VVCK 4TGFA 4JZDL 1ZAQA 5K0HB 2FZZL 1L5GB 3EGFA 3KL6B 1IQJL 3SOQA 1EPGA 1LPZA 2Q1JB 1G1TA 3HPTA 2VVVL 2WFTA 5JBCE 3C9AC 4BDXA 3K9XA 4NGAL 2PUQL 2TGFA 3TZIA 2FLRL 3LN1A 3N8XA 1N1IA 2DDUA 2WPKE 4Z6AL 1LMJA 2BOHA 1HREA 2K2SB 4RS0A 3Q3KB 1FAKL 1U67A 2BMGA 4MMZB 1HT5A 4AQTA 2YGOA 1DVAL 2VWMK 2WG4B 1UZKA 3SW2A 2UWLB
chains in the Genus database with same CATH superfamily
3KQCL 3HO5A 2WPME 2OYUP 3N8VA 3R05A 2YGQA 1Z6EL 2F9BL 3IJEB 3ENSA 2BOUA 2BQWA 1BF9A 1N7DA 3SOVA 3HO4A 3NTGA 4Y76B 5IKQA 3LTFB 4D90A 1UZJA 3PGHA 2FLGA 1EMOA 2EI6B 5KN5C 4COXA 4Z0LA 1CCFA 3HS6A 3M37L 5COXA 4RRXA 1P0SL 2NPRA 3KRKA 1OB1C 2W2PE 2BOKL 1W8BL 4XLWA 4Y7AB 4CUDA 2H9EL 1RFNB 2W3IB 1HAEA 1V1IA 1CVWL 5JW1A 1WU1B 1IP0A 5IKRA 2VWOL 1I0UA 1DX5I 2BQ6A 1IGZA 3TBDA 1EGFA 2CJIB 1FF7A 1UZQA 1IOXA 2VJ3A 1YUKB 5IKVA 3F1SB 1HRFA 1MOXC 5CISA 2Y81B 3U7UG 3F6UL 1WHFA 3U73A 1DQBA 3OLUA 1KIGL 1NFXB 4JYVL 1LPKA 2BSFA 2J94B 1EQGA 3H5CB 1CEJA 2RHPA 2P26A 5E8DA 4RUTA 1V3XB 1JV2B 1NQLB 2WZPP 4JZFL 3DEMA 1NFYB 1ATEA 1IGXA 3N8ZA 1JL9A 4X8TL 1CCVA 1COUA 1IQLL 1URKA 3TK6B 2MHPA 4ISHL 4ZHAB 5IKTA 4ISIL 4M11A 5FDQA 1FFMA 1X7AL 3KQDL 3N8WB 1LK9A 4D0EA 3KK6A 3KQBL 1IQFL 1HZ8A 3MQEA 1EQHA 1F7EA 4YZUB 1FJSL 1EPJA 1L3YA 1G1QA 1IOEL 2W86A 4ZAEB 2XC4L 1W7XL 1CVUA 4ZH8B 3V65B 2J4IB 3BT1A 1C5MF 2W3KB 4D0FA 1YO8A 1XKAL 2P94L 1ADXA 1F0SB 1TLEA 3IITB 2XBYL 5JVZA 5I46L 2KB9A 4XBMA 3GISX 5CKQA 2WPJE 3ZYJB 1ATDA 1G1RA 5JVYA 1KKEA 1QIUA 5JBBE 1AUTL 1LMMA 1IQIL 2Y38A 1GK5A 3CENL 4YT6L 2WFXB 1Q4GA 2J38B 1O5DL 3LC5B 4MMYB 2H9EC 3ZYIB 2WYGB 2Y5HL 2P3TA 4ZXYL 1F7MA 3TGFA 1PFXL 2P95L 3GCXE 3CFWA 3MDLA 1WHEA 1HCGB 2P93L 2ADXA 4BXSA 2VH0B 2JJLA 4OTJA 4CSYA 3OLTA 1IQNL 6COXA 4O02B 3NT1A 4Y7BB 1M1XB 1IQKL 1U8CB 4ZXXL 3NTBA 2Y82B 4RRZA 3V64C 4NG9L 4XL1A 4JZEL 2Y5FL 2BQ7A 1EBVA 1MQ6L 1XDTR 2J34B 4CUFA 1EAIC 2I9BA 2MGPA 4NA9L 1ATBA 2FLBL 2VRSA 3TH3L 4M10A 3N8WA 2G00L 1F0RB 4BTIA 1IQHL 1K36A 4MMXB 1DDXA 4X8VL 1HAFA 2XBXL 3N8YA 2KL7A 4O1ZA 3QH0A 2MGRA 5L30L 2WYJB 2XC0L 1J9CL 1TOZA 3ELAL 1YUGA 2BT7A 2WPIE 3BPSE 3QMOA 3FBYA 2XC5L 1NPEB 1PGEA 3POYA 2JKHL 2WPHE 1NZIA 2EI7B 1EZQB 3LAQA 2Y80B 3FFGL 1Z6CA 1ATAA 1CQEA 4Y6DB 2PR3B 2W2ME 1IJQA 2XBWL 2P3UA 4E1GA 2I9AA 3LIWB 3N8YB 2KNIA 2AYLA 3HO3A 2WG3C 5JBAE 2YGPA 5L2ZL 2WPLE 1HX2A 2Y7ZB 2BOXA 4Z0KB 1HT8A 4LORA 3FCSB 1B9WA 3ASIA 4OTYA 3LTGD 2XBVL 2HOXA 3NJPC 1XKBA 2BT8A 4PH9A 4C16A 1V1HA 2FD6A 5F19A 5CKNA 1FE2A 4BDWA 3M36L 1LPGA 1SZBA 1A3PA 4A7IA 1G1SA 1MQ5L 1EMNA 2B7DL 2M74A 2D1JB 1NFUB 2RNLA 4G1MB 3CS7L 1DIYA 4FM5A 4BTUA 1APQA 2W26B 4X8UL 2W2QE 1EPIA 2KV4A 2VVUL 3ZYGA 2Y5GL 1NFWB 5EGMB 1P9JA 1PXXA 3KQEL 1JBUL 1QFKL 3RR3A 1G2LB 2UWOB 1LQDA 4RRYA 4A94C 1NT0A 4Y79B 1HJ7A 3HS5A 4CUEA 2GD4A 5F1AA 2RA0L 2OYEP 2VWNL 2W2NE 3BT2A 1FAXL 4X8SL 1IQML 2VH6B 3CA7A 2K2TA 1KLOA 4RRWA 2HORA 2VWLL 1YGCL 3Q7DA 1PRHA 2J2UB 2P28B 2BO2A 4YT7L 1G2MB 3LC3B 3P5BL 1CX2A 3HS7A 1KLJL 3S6XA 2P16L 4BTTA 1FSBA 1TPGA 2PHBB 1K37A 1KLIL 1EPHA 1UZPA 5L2YL 3GCWE 1XFEA 1YUFA 2J95B 5JB9E 2W2OE 2BZ6L 2Y7XB 2P3FL 1IVOC 1PTHA 2EI8B 4GU4A 3SOBB 4BXWA 5KIRA 3TK5B 5JB8E 1APOA 1IQEL 3QCWA 4LMFA 1KSNB 1IQGL 4JYUL 5CKMA 4Y71B 2P3FN 2UWPB 3KCGL 3LN0A 2VVCK 4TGFA 4JZDL 1ZAQA 5K0HB 4GU3A 2FZZL 1L5GB 3EGFA 3KL6B 1IQJL 3SOQA 1EPGA 1LPZA 2Q1JB 1G1TA 3HPTA 2VVVL 2WFTA 5JBCE 3C9AC 4BDXA 3K9XA 4NGAL 2PUQL 2TGFA 3TZIA 2FLRL 3LN1A 3N8XA 1N1IA 2DDUA 2WPKE 4Z6AL 1LMJA 2BOHA 1HREA 2K2SB 4RS0A 3Q3KB 1FAKL 1U67A 2BMGA 4MMZB 1HT5A 4AQTA 2YGOA 1DVAL 2VWMK 2WG4B 1UZKA 3SW2A 2UWLB
chains in the Genus database with same CATH topology
3KQCL 3HO5A 2WPME 2OYUP 3N8VA 3R05A 2YGQA 1Z6EL 2F9BL 3IJEB 3ENSA 2BOUA 2BQWA 1BF9A 1N7DA 3SOVA 3HO4A 3NTGA 4Y76B 5IKQA 3LTFB 4D90A 1UZJA 3PGHA 2FLGA 1EMOA 2EI6B 5KN5C 4COXA 4Z0LA 1CCFA 3HS6A 3M37L 5COXA 4RRXA 1P0SL 2NPRA 3KRKA 1OB1C 2W2PE 2BOKL 1W8BL 4XLWA 4Y7AB 4CUDA 2H9EL 1RFNB 2W3IB 1HAEA 1CVWL 5JW1A 1WU1B 1IP0A 5IKRA 2VWOL 1I0UA 1DX5I 2BQ6A 1IGZA 3TBDA 1EGFA 2CJIB 1FF7A 1UZQA 1IOXA 2VJ3A 1YUKB 5IKVA 3F1SB 1HRFA 1MOXC 5CISA 2Y81B 3U7UG 3F6UL 1WHFA 3U73A 1DQBA 3OLUA 1KIGL 1NFXB 4JYVL 1LPKA 2J94B 1EQGA 3H5CB 1CEJA 2RHPA 2P26A 5E8DA 4RUTA 1V3XB 1JV2B 1NQLB 2WZPP 4JZFL 3DEMA 1NFYB 1ATEA 1IGXA 3N8ZA 1JL9A 4X8TL 1CCVA 1COUA 1IQLL 1URKA 3TK6B 2MHPA 4ISHL 4ZHAB 5IKTA 4ISIL 4M11A 5FDQA 1FFMA 1X7AL 3KQDL 3N8WB 4D0EA 3KK6A 3KQBL 1IQFL 1HZ8A 3MQEA 1EQHA 1F7EA 4YZUB 1FJSL 1EPJA 1L3YA 1G1QA 1IOEL 2W86A 4ZAEB 2XC4L 1W7XL 1CVUA 4ZH8B 3V65B 2J4IB 3BT1A 1C5MF 2W3KB 4D0FA 1YO8A 1XKAL 2P94L 1ADXA 1F0SB 1TLEA 3IITB 2XBYL 5JVZA 5I46L 2KB9A 4XBMA 3GISX 5CKQA 2WPJE 3ZYJB 1ATDA 1G1RA 5JVYA 5JBBE 1AUTL 1LMMA 1IQIL 2Y38A 1GK5A 3CENL 4YT6L 2WFXB 1Q4GA 2J38B 1O5DL 3LC5B 4MMYB 2H9EC 3ZYIB 2WYGB 2Y5HL 2P3TA 4ZXYL 1F7MA 3TGFA 1PFXL 2P95L 3GCXE 3CFWA 3MDLA 1WHEA 1HCGB 2P93L 2ADXA 4BXSA 2VH0B 4OTJA 4CSYA 3OLTA 1IQNL 6COXA 4O02B 3NT1A 4Y7BB 1M1XB 1IQKL 1U8CB 4ZXXL 3NTBA 2Y82B 4RRZA 3V64C 4NG9L 4XL1A 4JZEL 2Y5FL 2BQ7A 1EBVA 1MQ6L 1XDTR 2J34B 4CUFA 1EAIC 2I9BA 2MGPA 4NA9L 1ATBA 2FLBL 3TH3L 4M10A 3N8WA 2G00L 1F0RB 4BTIA 1IQHL 1K36A 4MMXB 1DDXA 4X8VL 1HAFA 2XBXL 3N8YA 2KL7A 4O1ZA 3QH0A 2MGRA 5L30L 2WYJB 2XC0L 1J9CL 1TOZA 3ELAL 1YUGA 2WPIE 3BPSE 3QMOA 3FBYA 2XC5L 1NPEB 1PGEA 3POYA 2JKHL 2WPHE 1NZIA 2EI7B 1EZQB 3LAQA 2Y80B 3FFGL 1Z6CA 1ATAA 1CQEA 4Y6DB 2PR3B 2W2ME 1IJQA 2XBWL 2P3UA 4E1GA 2I9AA 3LIWB 3N8YB 2KNIA 2AYLA 3HO3A 2WG3C 5JBAE 2YGPA 5L2ZL 2WPLE 1HX2A 2Y7ZB 2BOXA 4Z0KB 1HT8A 4LORA 3FCSB 1B9WA 3ASIA 4OTYA 3LTGD 2XBVL 3NJPC 1XKBA 4PH9A 4C16A 2FD6A 5F19A 5CKNA 1FE2A 4BDWA 3M36L 1LPGA 1SZBA 1A3PA 4A7IA 1G1SA 1MQ5L 1EMNA 2B7DL 2M74A 2D1JB 1NFUB 2RNLA 4G1MB 3CS7L 1DIYA 4FM5A 4BTUA 1APQA 2W26B 4X8UL 2W2QE 1EPIA 2KV4A 2VVUL 3ZYGA 2Y5GL 1NFWB 5EGMB 1P9JA 1PXXA 3KQEL 1JBUL 1QFKL 3RR3A 1G2LB 2UWOB 1LQDA 4RRYA 4A94C 1NT0A 4Y79B 1HJ7A 3HS5A 4CUEA 2GD4A 5F1AA 2RA0L 2OYEP 2VWNL 2W2NE 3BT2A 1FAXL 4X8SL 1IQML 2VH6B 3CA7A 2K2TA 1KLOA 4RRWA 2VWLL 1YGCL 3Q7DA 1PRHA 2J2UB 2P28B 2BO2A 4YT7L 1G2MB 3LC3B 3P5BL 1CX2A 3HS7A 1KLJL 3S6XA 2P16L 4BTTA 1FSBA 1TPGA 2PHBB 1K37A 1KLIL 1EPHA 1UZPA 5L2YL 3GCWE 1XFEA 1YUFA 2J95B 5JB9E 2W2OE 2BZ6L 2Y7XB 2P3FL 1IVOC 1PTHA 2EI8B 3SOBB 4BXWA 5KIRA 3TK5B 5JB8E 1APOA 1IQEL 3QCWA 4LMFA 1KSNB 1IQGL 4JYUL 5CKMA 4Y71B 2P3FN 2UWPB 3KCGL 3LN0A 2VVCK 4TGFA 4JZDL 1ZAQA 5K0HB 2FZZL 1L5GB 3EGFA 3KL6B 1IQJL 3SOQA 1EPGA 1LPZA 2Q1JB 1G1TA 3HPTA 2VVVL 2WFTA 5JBCE 3C9AC 4BDXA 3K9XA 4NGAL 2PUQL 2TGFA 3TZIA 2FLRL 3LN1A 3N8XA 1N1IA 2DDUA 2WPKE 4Z6AL 1LMJA 2BOHA 1HREA 2K2SB 4RS0A 3Q3KB 1FAKL 1U67A 2BMGA 4MMZB 1HT5A 4AQTA 2YGOA 1DVAL 2VWMK 2WG4B 1UZKA 3SW2A 2UWLB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KQC L;  3HO5 A;  2WPM E;  2OYU P;  3N8V A;  3R05 A;  1Z6E L;  2F9B L;  3IJE B;  3ENS A;  2BOU A;  2BQW A;  1BF9 A;  1N7D A;  3SOV A;  3HO4 A;  3NTG A;  4Y76 B;  5IKQ A;  3LTF B;  4D90 A;  1UZJ A;  3PGH A;  2FLG A;  1EMO A;  2EI6 B;  5KN5 C;  4COX A;  4Z0L A;  1CCF A;  3HS6 A;  3M37 L;  5COX A;  4RRX A;  1P0S L;  2NPR A;  3KRK A;  1OB1 C;  2W2P E;  2BOK L;  1W8B L;  4XLW A;  4Y7A B;  4CUD A;  2H9E L;  1RFN B;  2W3I B;  1HAE A;  1CVW L;  5JW1 A;  1WU1 B;  1IP0 A;  5IKR A;  2VWO L;  1I0U A;  1DX5 I;  2BQ6 A;  1IGZ A;  3TBD A;  1EGF A;  2CJI B;  1FF7 A;  1UZQ A;  1IOX A;  2VJ3 A;  1YUK B;  5IKV A;  3F1S B;  1HRF A;  1MOX C;  5CIS A;  2Y81 B;  3U7U G;  3F6U L;  1WHF A;  3U73 A;  1DQB A;  3OLU A;  1KIG L;  1NFX B;  4JYV L;  1LPK A;  2J94 B;  1EQG A;  3H5C B;  1CEJ A;  2RHP A;  2P26 A;  5E8D A;  4RUT A;  1V3X B;  1JV2 B;  1NQL B;  4JZF L;  3DEM A;  1NFY B;  1ATE A;  1IGX A;  3N8Z A;  1JL9 A;  4X8T L;  1CCV A;  1COU A;  1IQL L;  1URK A;  3TK6 B;  2MHP A;  4ISH L;  4ZHA B;  5IKT A;  4ISI L;  4M11 A;  5FDQ A;  1FFM A;  1X7A L;  3KQD L;  3N8W B;  4D0E A;  3KK6 A;  3KQB L;  1IQF L;  1HZ8 A;  3MQE A;  1EQH A;  1F7E A;  4YZU B;  1FJS L;  1EPJ A;  1L3Y A;  1G1Q A;  1IOE L;  2W86 A;  4ZAE B;  2XC4 L;  1W7X L;  1CVU A;  4ZH8 B;  3V65 B;  2J4I B;  3BT1 A;  1C5M F;  2W3K B;  4D0F A;  1YO8 A;  1XKA L;  2P94 L;  1ADX A;  1F0S B;  1TLE A;  3IIT B;  2XBY L;  5JVZ A;  5I46 L;  2KB9 A;  4XBM A;  3GIS X;  5CKQ A;  2WPJ E;  3ZYJ B;  1ATD A;  1G1R A;  5JVY A;  5JBB E;  1AUT L;  1IQI L;  2Y38 A;  1GK5 A;  3CEN L;  4YT6 L;  2WFX B;  1Q4G A;  2J38 B;  1O5D L;  3LC5 B;  4MMY B;  3ZYI B;  2WYG B;  2Y5H L;  2P3T A;  4ZXY L;  1F7M A;  3TGF A;  1PFX L;  2P95 L;  3GCX E;  3CFW A;  3MDL A;  1WHE A;  1HCG B;  2P93 L;  2ADX A;  4BXS A;  2VH0 B;  4OTJ A;  4CSY A;  3OLT A;  1IQN L;  6COX A;  4O02 B;  3NT1 A;  4Y7B B;  1M1X B;  1IQK L;  1U8C B;  4ZXX L;  3NTB A;  2Y82 B;  4RRZ A;  3V64 C;  4NG9 L;  4XL1 A;  4JZE L;  2Y5F L;  2BQ7 A;  1EBV A;  1MQ6 L;  1XDT R;  2J34 B;  4CUF A;  1EAI C;  2I9B A;  2MGP A;  4NA9 L;  1ATB A;  2FLB L;  3TH3 L;  4M10 A;  3N8W A;  2G00 L;  1F0R B;  4BTI A;  1IQH L;  1K36 A;  4MMX B;  1DDX A;  4X8V L;  1HAF A;  2XBX L;  3N8Y A;  2KL7 A;  4O1Z A;  3QH0 A;  2MGR A;  5L30 L;  2WYJ B;  2XC0 L;  1J9C L;  1TOZ A;  3ELA L;  1YUG A;  2WPI E;  3BPS E;  3QMO A;  3FBY A;  2XC5 L;  1NPE B;  1PGE A;  3POY A;  2JKH L;  2WPH E;  1NZI A;  2EI7 B;  1EZQ B;  3LAQ A;  2Y80 B;  3FFG L;  1Z6C A;  1ATA A;  1CQE A;  4Y6D B;  2PR3 B;  2W2M E;  1IJQ A;  2XBW L;  2P3U A;  4E1G A;  2I9A A;  3LIW B;  3N8Y B;  2AYL A;  3HO3 A;  2WG3 C;  5JBA E;  2YGP A;  5L2Z L;  2WPL E;  1HX2 A;  2Y7Z B;  2BOX A;  4Z0K B;  1HT8 A;  4LOR A;  3FCS B;  1B9W A;  3ASI A;  4OTY A;  3LTG D;  2XBV L;  3NJP C;  1XKB A;  4PH9 A;  4C16 A;  2FD6 A;  5F19 A;  5CKN A;  1FE2 A;  4BDW A;  3M36 L;  1LPG A;  1SZB A;  1A3P A;  4A7I A;  1G1S A;  1MQ5 L;  1EMN A;  2B7D L;  2M74 A;  2D1J B;  1NFU B;  2RNL A;  4G1M B;  3CS7 L;  1DIY A;  4FM5 A;  4BTU A;  1APQ A;  2W26 B;  4X8U L;  2W2Q E;  1EPI A;  2KV4 A;  2VVU L;  3ZYG A;  2Y5G L;  1NFW B;  5EGM B;  1P9J A;  1PXX A;  3KQE L;  1JBU L;  1QFK L;  3RR3 A;  1G2L B;  2UWO B;  1LQD A;  4RRY A;  1NT0 A;  4Y79 B;  1HJ7 A;  3HS5 A;  4CUE A;  2GD4 A;  5F1A A;  2RA0 L;  2OYE P;  2VWN L;  2W2N E;  3BT2 A;  1FAX L;  4X8S L;  1IQM L;  2VH6 B;  3CA7 A;  2K2T A;  1KLO A;  4RRW A;  2VWL L;  1YGC L;  3Q7D A;  1PRH A;  2J2U B;  2P28 B;  2BO2 A;  4YT7 L;  1G2M B;  3LC3 B;  3P5B L;  1CX2 A;  3HS7 A;  1KLJ L;  2P16 L;  4BTT A;  1FSB A;  1TPG A;  2PHB B;  1K37 A;  1KLI L;  1EPH A;  1UZP A;  5L2Y L;  3GCW E;  1XFE A;  1YUF A;  2J95 B;  5JB9 E;  2W2O E;  2BZ6 L;  2Y7X B;  2P3F L;  1IVO C;  1PTH A;  2EI8 B;  3SOB B;  4BXW A;  5KIR A;  3TK5 B;  5JB8 E;  1APO A;  1IQE L;  3QCW A;  4LMF A;  1KSN B;  1IQG L;  4JYU L;  5CKM A;  4Y71 B;  2P3F N;  2UWP B;  3KCG L;  3LN0 A;  2VVC K;  4TGF A;  4JZD L;  1ZAQ A;  5K0H B;  2FZZ L;  1L5G B;  3EGF A;  3KL6 B;  1IQJ L;  3SOQ A;  1EPG A;  1LPZ A;  2Q1J B;  1G1T A;  3HPT A;  2VVV L;  2WFT A;  5JBC E;  3C9A C;  4BDX A;  3K9X A;  4NGA L;  2PUQ L;  2TGF A;  3TZI A;  2FLR L;  3LN1 A;  3N8X A;  1N1I A;  2DDU A;  2WPK E;  4Z6A L;  1LMJ A;  2BOH A;  1HRE A;  2K2S B;  4RS0 A;  3Q3K B;  1FAK L;  1U67 A;  2BMG A;  4MMZ B;  1HT5 A;  4AQT A;  2YGO A;  1DVA L;  2VWM K;  2WG4 B;  1UZK A;  3SW2 A;  2UWL B; 
#chains in the Genus database with same CATH topology
 3KQC L;  3HO5 A;  2WPM E;  2OYU P;  3N8V A;  3R05 A;  2YGQ A;  1Z6E L;  2F9B L;  3IJE B;  3ENS A;  2BOU A;  2BQW A;  1BF9 A;  1N7D A;  3SOV A;  3HO4 A;  3NTG A;  4Y76 B;  5IKQ A;  3LTF B;  4D90 A;  1UZJ A;  3PGH A;  2FLG A;  1EMO A;  2EI6 B;  5KN5 C;  4COX A;  4Z0L A;  1CCF A;  3HS6 A;  3M37 L;  5COX A;  4RRX A;  1P0S L;  2NPR A;  3KRK A;  1OB1 C;  2W2P E;  2BOK L;  1W8B L;  4XLW A;  4Y7A B;  4CUD A;  2H9E L;  1RFN B;  2W3I B;  1HAE A;  1V1I A;  1CVW L;  5JW1 A;  1WU1 B;  1IP0 A;  5IKR A;  2VWO L;  1I0U A;  1DX5 I;  2BQ6 A;  1IGZ A;  3TBD A;  1EGF A;  2CJI B;  1FF7 A;  1UZQ A;  1IOX A;  2VJ3 A;  1YUK B;  5IKV A;  3F1S B;  1HRF A;  1MOX C;  5CIS A;  2Y81 B;  3U7U G;  3F6U L;  1WHF A;  3U73 A;  1DQB A;  3OLU A;  1KIG L;  1NFX B;  4JYV L;  1LPK A;  2BSF A;  2J94 B;  1EQG A;  3H5C B;  1CEJ A;  2RHP A;  2P26 A;  5E8D A;  4RUT A;  1V3X B;  1JV2 B;  1NQL B;  2WZP P;  4JZF L;  3DEM A;  1NFY B;  1ATE A;  1IGX A;  3N8Z A;  1JL9 A;  4X8T L;  1CCV A;  1COU A;  1IQL L;  1URK A;  3TK6 B;  2MHP A;  4ISH L;  4ZHA B;  5IKT A;  4ISI L;  4M11 A;  5FDQ A;  1FFM A;  1X7A L;  3KQD L;  3N8W B;  1LK9 A;  4D0E A;  3KK6 A;  3KQB L;  1IQF L;  1HZ8 A;  3MQE A;  1EQH A;  1F7E A;  4YZU B;  1FJS L;  1EPJ A;  1L3Y A;  1G1Q A;  1IOE L;  2W86 A;  4ZAE B;  2XC4 L;  1W7X L;  1CVU A;  4ZH8 B;  3V65 B;  2J4I B;  3BT1 A;  1C5M F;  2W3K B;  4D0F A;  1YO8 A;  1XKA L;  2P94 L;  1ADX A;  1F0S B;  1TLE A;  3IIT B;  2XBY L;  5JVZ A;  5I46 L;  2KB9 A;  4XBM A;  3GIS X;  5CKQ A;  2WPJ E;  3ZYJ B;  1ATD A;  1G1R A;  5JVY A;  1KKE A;  1QIU A;  5JBB E;  1AUT L;  1LMM A;  1IQI L;  2Y38 A;  1GK5 A;  3CEN L;  4YT6 L;  2WFX B;  1Q4G A;  2J38 B;  1O5D L;  3LC5 B;  4MMY B;  2H9E C;  3ZYI B;  2WYG B;  2Y5H L;  2P3T A;  4ZXY L;  1F7M A;  3TGF A;  1PFX L;  2P95 L;  3GCX E;  3CFW A;  3MDL A;  1WHE A;  1HCG B;  2P93 L;  2ADX A;  4BXS A;  2VH0 B;  2JJL A;  4OTJ A;  4CSY A;  3OLT A;  1IQN L;  6COX A;  4O02 B;  3NT1 A;  4Y7B B;  1M1X B;  1IQK L;  1U8C B;  4ZXX L;  3NTB A;  2Y82 B;  4RRZ A;  3V64 C;  4NG9 L;  4XL1 A;  4JZE L;  2Y5F L;  2BQ7 A;  1EBV A;  1MQ6 L;  1XDT R;  2J34 B;  4CUF A;  1EAI C;  2I9B A;  2MGP A;  4NA9 L;  1ATB A;  2FLB L;  2VRS A;  3TH3 L;  4M10 A;  3N8W A;  2G00 L;  1F0R B;  4BTI A;  1IQH L;  1K36 A;  4MMX B;  1DDX A;  4X8V L;  1HAF A;  2XBX L;  3N8Y A;  2KL7 A;  4O1Z A;  3QH0 A;  2MGR A;  5L30 L;  2WYJ B;  2XC0 L;  1J9C L;  1TOZ A;  3ELA L;  1YUG A;  2BT7 A;  2WPI E;  3BPS E;  3QMO A;  3FBY A;  2XC5 L;  1NPE B;  1PGE A;  3POY A;  2JKH L;  2WPH E;  1NZI A;  2EI7 B;  1EZQ B;  3LAQ A;  2Y80 B;  3FFG L;  1Z6C A;  1ATA A;  1CQE A;  4Y6D B;  2PR3 B;  2W2M E;  1IJQ A;  2XBW L;  2P3U A;  4E1G A;  2I9A A;  3LIW B;  3N8Y B;  2KNI A;  2AYL A;  3HO3 A;  2WG3 C;  5JBA E;  2YGP A;  5L2Z L;  2WPL E;  1HX2 A;  2Y7Z B;  2BOX A;  4Z0K B;  1HT8 A;  4LOR A;  3FCS B;  1B9W A;  3ASI A;  4OTY A;  3LTG D;  2XBV L;  2HOX A;  3NJP C;  1XKB A;  2BT8 A;  4PH9 A;  4C16 A;  1V1H A;  2FD6 A;  5F19 A;  5CKN A;  1FE2 A;  4BDW A;  3M36 L;  1LPG A;  1SZB A;  1A3P A;  4A7I A;  1G1S A;  1MQ5 L;  1EMN A;  2B7D L;  2M74 A;  2D1J B;  1NFU B;  2RNL A;  4G1M B;  3CS7 L;  1DIY A;  4FM5 A;  4BTU A;  1APQ A;  2W26 B;  4X8U L;  2W2Q E;  1EPI A;  2KV4 A;  2VVU L;  3ZYG A;  2Y5G L;  1NFW B;  5EGM B;  1P9J A;  1PXX A;  3KQE L;  1JBU L;  1QFK L;  3RR3 A;  1G2L B;  2UWO B;  1LQD A;  4RRY A;  4A94 C;  1NT0 A;  4Y79 B;  1HJ7 A;  3HS5 A;  4CUE A;  2GD4 A;  5F1A A;  2RA0 L;  2OYE P;  2VWN L;  2W2N E;  3BT2 A;  1FAX L;  4X8S L;  1IQM L;  2VH6 B;  3CA7 A;  2K2T A;  1KLO A;  4RRW A;  2HOR A;  2VWL L;  1YGC L;  3Q7D A;  1PRH A;  2J2U B;  2P28 B;  2BO2 A;  4YT7 L;  1G2M B;  3LC3 B;  3P5B L;  1CX2 A;  3HS7 A;  1KLJ L;  3S6X A;  2P16 L;  4BTT A;  1FSB A;  1TPG A;  2PHB B;  1K37 A;  1KLI L;  1EPH A;  1UZP A;  5L2Y L;  3GCW E;  1XFE A;  1YUF A;  2J95 B;  5JB9 E;  2W2O E;  2BZ6 L;  2Y7X B;  2P3F L;  1IVO C;  1PTH A;  2EI8 B;  4GU4 A;  3SOB B;  4BXW A;  5KIR A;  3TK5 B;  5JB8 E;  1APO A;  1IQE L;  3QCW A;  4LMF A;  1KSN B;  1IQG L;  4JYU L;  5CKM A;  4Y71 B;  2P3F N;  2UWP B;  3KCG L;  3LN0 A;  2VVC K;  4TGF A;  4JZD L;  1ZAQ A;  5K0H B;  4GU3 A;  2FZZ L;  1L5G B;  3EGF A;  3KL6 B;  1IQJ L;  3SOQ A;  1EPG A;  1LPZ A;  2Q1J B;  1G1T A;  3HPT A;  2VVV L;  2WFT A;  5JBC E;  3C9A C;  4BDX A;  3K9X A;  4NGA L;  2PUQ L;  2TGF A;  3TZI A;  2FLR L;  3LN1 A;  3N8X A;  1N1I A;  2DDU A;  2WPK E;  4Z6A L;  1LMJ A;  2BOH A;  1HRE A;  2K2S B;  4RS0 A;  3Q3K B;  1FAK L;  1U67 A;  2BMG A;  4MMZ B;  1HT5 A;  4AQT A;  2YGO A;  1DVA L;  2VWM K;  2WG4 B;  1UZK A;  3SW2 A;  2UWL B; 
#chains in the Genus database with same CATH homology
 3KQC L;  3HO5 A;  2WPM E;  2OYU P;  3N8V A;  3R05 A;  2YGQ A;  1Z6E L;  2F9B L;  3IJE B;  3ENS A;  2BOU A;  2BQW A;  1BF9 A;  1N7D A;  3SOV A;  3HO4 A;  3NTG A;  4Y76 B;  5IKQ A;  3LTF B;  4D90 A;  1UZJ A;  3PGH A;  2FLG A;  1EMO A;  2EI6 B;  5KN5 C;  4COX A;  4Z0L A;  1CCF A;  3HS6 A;  3M37 L;  5COX A;  4RRX A;  1P0S L;  2NPR A;  3KRK A;  1OB1 C;  2W2P E;  2BOK L;  1W8B L;  4XLW A;  4Y7A B;  4CUD A;  2H9E L;  1RFN B;  2W3I B;  1HAE A;  1CVW L;  5JW1 A;  1WU1 B;  1IP0 A;  5IKR A;  2VWO L;  1I0U A;  1DX5 I;  2BQ6 A;  1IGZ A;  3TBD A;  1EGF A;  2CJI B;  1FF7 A;  1UZQ A;  1IOX A;  2VJ3 A;  1YUK B;  5IKV A;  3F1S B;  1HRF A;  1MOX C;  5CIS A;  2Y81 B;  3U7U G;  3F6U L;  1WHF A;  3U73 A;  1DQB A;  3OLU A;  1KIG L;  1NFX B;  4JYV L;  1LPK A;  2J94 B;  1EQG A;  3H5C B;  1CEJ A;  2RHP A;  2P26 A;  5E8D A;  4RUT A;  1V3X B;  1JV2 B;  1NQL B;  2WZP P;  4JZF L;  3DEM A;  1NFY B;  1ATE A;  1IGX A;  3N8Z A;  1JL9 A;  4X8T L;  1CCV A;  1COU A;  1IQL L;  1URK A;  3TK6 B;  2MHP A;  4ISH L;  4ZHA B;  5IKT A;  4ISI L;  4M11 A;  5FDQ A;  1FFM A;  1X7A L;  3KQD L;  3N8W B;  4D0E A;  3KK6 A;  3KQB L;  1IQF L;  1HZ8 A;  3MQE A;  1EQH A;  1F7E A;  4YZU B;  1FJS L;  1EPJ A;  1L3Y A;  1G1Q A;  1IOE L;  2W86 A;  4ZAE B;  2XC4 L;  1W7X L;  1CVU A;  4ZH8 B;  3V65 B;  2J4I B;  3BT1 A;  1C5M F;  2W3K B;  4D0F A;  1YO8 A;  1XKA L;  2P94 L;  1ADX A;  1F0S B;  1TLE A;  3IIT B;  2XBY L;  5JVZ A;  5I46 L;  2KB9 A;  4XBM A;  3GIS X;  5CKQ A;  2WPJ E;  3ZYJ B;  1ATD A;  1G1R A;  5JVY A;  5JBB E;  1AUT L;  1LMM A;  1IQI L;  2Y38 A;  1GK5 A;  3CEN L;  4YT6 L;  2WFX B;  1Q4G A;  2J38 B;  1O5D L;  3LC5 B;  4MMY B;  2H9E C;  3ZYI B;  2WYG B;  2Y5H L;  2P3T A;  4ZXY L;  1F7M A;  3TGF A;  1PFX L;  2P95 L;  3GCX E;  3CFW A;  3MDL A;  1WHE A;  1HCG B;  2P93 L;  2ADX A;  4BXS A;  2VH0 B;  4OTJ A;  4CSY A;  3OLT A;  1IQN L;  6COX A;  4O02 B;  3NT1 A;  4Y7B B;  1M1X B;  1IQK L;  1U8C B;  4ZXX L;  3NTB A;  2Y82 B;  4RRZ A;  3V64 C;  4NG9 L;  4XL1 A;  4JZE L;  2Y5F L;  2BQ7 A;  1EBV A;  1MQ6 L;  1XDT R;  2J34 B;  4CUF A;  1EAI C;  2I9B A;  2MGP A;  4NA9 L;  1ATB A;  2FLB L;  3TH3 L;  4M10 A;  3N8W A;  2G00 L;  1F0R B;  4BTI A;  1IQH L;  1K36 A;  4MMX B;  1DDX A;  4X8V L;  1HAF A;  2XBX L;  3N8Y A;  2KL7 A;  4O1Z A;  3QH0 A;  2MGR A;  5L30 L;  2WYJ B;  2XC0 L;  1J9C L;  1TOZ A;  3ELA L;  1YUG A;  2WPI E;  3BPS E;  3QMO A;  3FBY A;  2XC5 L;  1NPE B;  1PGE A;  3POY A;  2JKH L;  2WPH E;  1NZI A;  2EI7 B;  1EZQ B;  3LAQ A;  2Y80 B;  3FFG L;  1Z6C A;  1ATA A;  1CQE A;  4Y6D B;  2PR3 B;  2W2M E;  1IJQ A;  2XBW L;  2P3U A;  4E1G A;  2I9A A;  3LIW B;  3N8Y B;  2KNI A;  2AYL A;  3HO3 A;  2WG3 C;  5JBA E;  2YGP A;  5L2Z L;  2WPL E;  1HX2 A;  2Y7Z B;  2BOX A;  4Z0K B;  1HT8 A;  4LOR A;  3FCS B;  1B9W A;  3ASI A;  4OTY A;  3LTG D;  2XBV L;  3NJP C;  1XKB A;  4PH9 A;  4C16 A;  2FD6 A;  5F19 A;  5CKN A;  1FE2 A;  4BDW A;  3M36 L;  1LPG A;  1SZB A;  1A3P A;  4A7I A;  1G1S A;  1MQ5 L;  1EMN A;  2B7D L;  2M74 A;  2D1J B;  1NFU B;  2RNL A;  4G1M B;  3CS7 L;  1DIY A;  4FM5 A;  4BTU A;  1APQ A;  2W26 B;  4X8U L;  2W2Q E;  1EPI A;  2KV4 A;  2VVU L;  3ZYG A;  2Y5G L;  1NFW B;  5EGM B;  1P9J A;  1PXX A;  3KQE L;  1JBU L;  1QFK L;  3RR3 A;  1G2L B;  2UWO B;  1LQD A;  4RRY A;  4A94 C;  1NT0 A;  4Y79 B;  1HJ7 A;  3HS5 A;  4CUE A;  2GD4 A;  5F1A A;  2RA0 L;  2OYE P;  2VWN L;  2W2N E;  3BT2 A;  1FAX L;  4X8S L;  1IQM L;  2VH6 B;  3CA7 A;  2K2T A;  1KLO A;  4RRW A;  2VWL L;  1YGC L;  3Q7D A;  1PRH A;  2J2U B;  2P28 B;  2BO2 A;  4YT7 L;  1G2M B;  3LC3 B;  3P5B L;  1CX2 A;  3HS7 A;  1KLJ L;  3S6X A;  2P16 L;  4BTT A;  1FSB A;  1TPG A;  2PHB B;  1K37 A;  1KLI L;  1EPH A;  1UZP A;  5L2Y L;  3GCW E;  1XFE A;  1YUF A;  2J95 B;  5JB9 E;  2W2O E;  2BZ6 L;  2Y7X B;  2P3F L;  1IVO C;  1PTH A;  2EI8 B;  3SOB B;  4BXW A;  5KIR A;  3TK5 B;  5JB8 E;  1APO A;  1IQE L;  3QCW A;  4LMF A;  1KSN B;  1IQG L;  4JYU L;  5CKM A;  4Y71 B;  2P3F N;  2UWP B;  3KCG L;  3LN0 A;  2VVC K;  4TGF A;  4JZD L;  1ZAQ A;  5K0H B;  2FZZ L;  1L5G B;  3EGF A;  3KL6 B;  1IQJ L;  3SOQ A;  1EPG A;  1LPZ A;  2Q1J B;  1G1T A;  3HPT A;  2VVV L;  2WFT A;  5JBC E;  3C9A C;  4BDX A;  3K9X A;  4NGA L;  2PUQ L;  2TGF A;  3TZI A;  2FLR L;  3LN1 A;  3N8X A;  1N1I A;  2DDU A;  2WPK E;  4Z6A L;  1LMJ A;  2BOH A;  1HRE A;  2K2S B;  4RS0 A;  3Q3K B;  1FAK L;  1U67 A;  2BMG A;  4MMZ B;  1HT5 A;  4AQT A;  2YGO A;  1DVA L;  2VWM K;  2WG4 B;  1UZK A;  3SW2 A;  2UWL B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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