4AOKB

Conformational dynamics of aspartate alpha-decarboxylase active site revealed by protein-ligand complexes: 1-methyl-l-aspartate complex
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
98
structure length
98
Chain Sequence
CAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Dynamics of Aspartate Alpha Decarboxylase Active Site Revealed by Protein-Ligand Complexes
rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords ASPARTATE 1-DECARBOXYLASE BETA CHAIN
total genus 24
structure length 98
sequence length 98
chains with identical sequence E
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2012-03-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4aokB00
2VPZA 2DMRA 2VPWA 3HKZA 5C1BA 5C18A 3H0GA 1R27A 2NAPA 1G8KA 2WAQA 4QIWA 2JIRA 4AOKB 5FTMA 1FDIA 2Y0SA 1Y1WA 4CS0A 1PPYA 1QCSA 3GTQA 2JIQA 3GTOA 3CF2A 2R93A 2R92A 5DYGA 1AW8B 2PMZA 1UHDA 2JA7A 3QWZA 4AAYA 1SFOA 1PQEA 1VC3B 2E2HA 3ML1A 5GLFA 3DMRA 1DMRA 3HU2A 1E60A 2EEOB 1R7RA 3IR6A 2R7ZA 3GTLA 1PYUB 5DYIA 2VPYA 1CZ4A 1H0HA 1S3SA 3IR5A 1E32A 2YU9A 1PT1A 1E61A 3TIWA 4GA6A 1KQGA 2JA5A 1E5VA 1CR5A 2C45A 4AYBA 4KDIA 4D7ZB 2E2IA 3GTMA 2JA6A 1R9TA 1FDOA 3FKIA 4CRYG 4GA5A 1H5NA 3O5AA 3QQ8A 4AONB 1Q16A 3QQ7A 1K83A 5FTLA 2VUMA 5T5ID 5FTNA 5B6CA 2NYAA 2KI8A 4RV0A 3IR7A 4AZDA 2V45A 3QC8A 1I50A 2WB1A 2JIOA 3GTKA 1WCMA 2E7ZA 2NVYA 5FTKA 4KO8A 3HU1A 1TWFA 1TMOA 2V3VA 1Y1VA 1QDNA 1UHEA 1TWGA 3PLXB 4DMRA 1TWCA 3HU3A 2B63A 1PQHA 3GTJA 4KDLA 2IV2X 1YLEA 4CRZA 4C2MA 1PT0A 2JIMA 1TWHA 5T5MD 2VPXA 2JIPA 2PJHB 3GTPA 1Y5IA 1KQFA 1WLFA 3GTGA 5FTJA 1E18A 1PQFA 2NVXA 3OUGA 1AA6A 1I3QA 1PYQA 1G8JA 5EPPA 3CQZA 1OGYA 1EU1A 1TWAA 1Y4ZA 4KLNA 4KODA 3TM7B 1CZ5A 1DMSA 1IW7D 1SIWA
chains in the Genus database with same CATH superfamily
2VPZA 2DMRA 2VPWA 3HKZA 1YNJD 5C1BA 5C18A 3H0GA 1R27A 1YNND 4FERA 2NAPA 1G8KA 2WAQA 4QIWA 2KQAA 2A69D 3CZBA 2A68D 2JIRA 4AOKB 5FTMA 5H4UA 3X2LA 1FDIA 2Y0SA 1Y1WA 4CS0A 1SMYD 1PPYA 1QCSA 2BE5D 2HCZX 1IW7D 2JIQA 3X2NA 3X2KA 3GTQA 3GTOA 3CF2A 2R93A 2R92A 5DYGA 1AW8B 2G5DA 1UHDA 2A6HD 2PJJA 2PMZA 4JCWA 3D30A 2JA7A 3QWZA 2BH0A 2PNWA 4AAYA 1SFOA 1PQEA 1VC3B 4FG2A 2E2HA 3ML1A 5GLFA 1OA9A 3DMRA 1DMRA 3HU2A 1E60A 1BW4A 2EEOB 2CW0D 4ZM7A 3SUKA 1R7RA 3IR6A 4ENGA 2R7ZA 3GTLA 1PYUB 5DYIA 2VPYA 1CZ4A 2ENGA 1H0HA 1S3SA 3IR5A 3X2JA 1E32A 2YU9A 1PT1A 3ENGA 1E61A 3TIWA 4GA6A 1KQGA 2JA5A 1E5VA 1CR5A 2C45A 4AYBA 4JP7A 4KDIA 4D7ZB 2E2IA 3GTMA 2JA6A 1R9TA 1FDOA 3FKIA 4CRYG 4GA5A 1H5NA 3O5AA 3QQ8A 2YUJA 4AONB 4AVRA 1Q16A 3QQ7A 1K83A 5FTLA 3X2HA 5T5ID 2VUMA 3M3GA 5FTNA 3SUJA 5B6CA 2PICA 2NYAA 4JJOA 3X2GA 2AE0X 1OA7A 2KI8A 4RV0A 3IR7A 1HD5A 4AZDA 4NOHA 2V45A 3QC8A 2G6GA 4JP6A 2WB1A 1I50A 2JIOA 3GTKA 1WCMA 2E7ZA 2NVYA 4L48A 5FTKA 3X2OA 1BW3A 4KO8A 5GM9A 4JS7A 2PI8A 4FG4A 5GLYA 3HU1A 1TWFA 1N10A 1TMOA 2GAEA 2V3VA 1Y1VA 1QDNA 1UHEA 5GLXA 1TWGA 3PLXB 4DMRA 1TWCA 3HU3A 2B63A 3X2PA 1PQHA 1ZYRD 3GTJA 4KDLA 2IV2X 1YLEA 4CRZA 4C2MA 1PT0A 2JIMA 1TWHA 4FFTA 5T5MD 2VPXA 2JIPA 2PJHB 3X2MA 3GTPA 1Y5IA 1KQFA 1WLFA 3GTGA 5FTJA 1E18A 1PQFA 2NVXA 3SUMA 3OUGA 3SULA 1AA6A 1I3QA 1WC2A 1PYQA 1ZC1A 1G8JA 2A6ED 5EPPA 3CQZA 1OGYA 3X2IA 1EU1A 1TWAA 1Y4ZA 4KLNA 4KODA 3TM7B 1CZ5A 1DMSA 1L8FA 2O5JD 1SIWA
chains in the Genus database with same CATH topology
2VPZA 2DMRA 2VPWA 3HKZA 1YNJD 5C1BA 5C18A 3H0GA 1R27A 1YNND 2NAPA 1G8KA 2WAQA 4QIWA 2A69D 3CZBA 2A68D 2JIRA 4AOKB 5FTMA 1FDIA 2Y0SA 1Y1WA 4CS0A 1SMYD 1PPYA 1QCSA 2BE5D 3GTQA 2JIQA 3GTOA 3CF2A 2R93A 2R92A 5DYGA 1AW8B 2G5DA 1UHDA 2A6HD 2PJJA 2PMZA 2JA7A 3QWZA 2PNWA 4AAYA 1SFOA 1PQEA 1VC3B 2E2HA 3ML1A 5GLFA 3DMRA 1DMRA 3HU2A 1E60A 2EEOB 2CW0D 1R7RA 3IR6A 2R7ZA 3GTLA 1PYUB 5DYIA 2VPYA 1CZ4A 1H0HA 1S3SA 3IR5A 1E32A 2YU9A 1PT1A 1E61A 3TIWA 4GA6A 1KQGA 2JA5A 1E5VA 1CR5A 2C45A 4AYBA 4KDIA 4D7ZB 2E2IA 3GTMA 2JA6A 1R9TA 1FDOA 3FKIA 4CRYG 4GA5A 1H5NA 3O5AA 3QQ8A 2YUJA 4AONB 1Q16A 3QQ7A 1K83A 5FTLA 2VUMA 5T5ID 5FTNA 5B6CA 2PICA 2NYAA 2AE0X 2KI8A 4RV0A 3IR7A 4AZDA 4NOHA 2V45A 3QC8A 2G6GA 1I50A 2WB1A 2JIOA 3GTKA 1WCMA 2E7ZA 2NVYA 5FTKA 4KO8A 2PI8A 3HU1A 1TWFA 1TMOA 2GAEA 2V3VA 1Y1VA 1QDNA 1UHEA 1TWGA 3PLXB 4DMRA 1TWCA 3HU3A 2B63A 1PQHA 1ZYRD 3GTJA 4KDLA 2IV2X 1YLEA 4CRZA 4C2MA 1PT0A 2JIMA 1TWHA 5T5MD 2VPXA 2JIPA 2PJHB 3GTPA 1Y5IA 1KQFA 1WLFA 3GTGA 5FTJA 1E18A 1PQFA 2NVXA 3OUGA 1AA6A 1I3QA 1PYQA 1ZC1A 1G8JA 2A6ED 5EPPA 3CQZA 1OGYA 1EU1A 1TWAA 1Y4ZA 4KLNA 4KODA 3TM7B 1CZ5A 1DMSA 1IW7D 2O5JD 1SIWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VPZ A;  2DMR A;  2VPW A;  3HKZ A;  5C1B A;  5C18 A;  3H0G A;  1R27 A;  2NAP A;  1G8K A;  2WAQ A;  4QIW A;  2JIR A;  4AOK B;  5FTM A;  1FDI A;  2Y0S A;  1Y1W A;  4CS0 A;  1PPY A;  1QCS A;  3GTQ A;  2JIQ A;  3GTO A;  3CF2 A;  2R93 A;  2R92 A;  5DYG A;  1AW8 B;  2PMZ A;  1UHD A;  2JA7 A;  3QWZ A;  4AAY A;  1SFO A;  1PQE A;  1VC3 B;  2E2H A;  3ML1 A;  5GLF A;  3DMR A;  1DMR A;  3HU2 A;  1E60 A;  2EEO B;  1R7R A;  3IR6 A;  2R7Z A;  3GTL A;  1PYU B;  5DYI A;  2VPY A;  1CZ4 A;  1H0H A;  1S3S A;  3IR5 A;  1E32 A;  2YU9 A;  1PT1 A;  1E61 A;  3TIW A;  4GA6 A;  1KQG A;  2JA5 A;  1E5V A;  1CR5 A;  2C45 A;  4AYB A;  4KDI A;  4D7Z B;  2E2I A;  3GTM A;  2JA6 A;  1R9T A;  1FDO A;  3FKI A;  4CRY G;  4GA5 A;  1H5N A;  3O5A A;  3QQ8 A;  4AON B;  1Q16 A;  3QQ7 A;  1K83 A;  5FTL A;  2VUM A;  5T5I D;  5FTN A;  5B6C A;  2NYA A;  2KI8 A;  4RV0 A;  3IR7 A;  4AZD A;  2V45 A;  3QC8 A;  1I50 A;  2WB1 A;  2JIO A;  3GTK A;  1WCM A;  2E7Z A;  2NVY A;  5FTK A;  4KO8 A;  3HU1 A;  1TWF A;  1TMO A;  2V3V A;  1Y1V A;  1QDN A;  1UHE A;  1TWG A;  3PLX B;  4DMR A;  1TWC A;  3HU3 A;  2B63 A;  1PQH A;  3GTJ A;  4KDL A;  2IV2 X;  1YLE A;  4CRZ A;  4C2M A;  1PT0 A;  2JIM A;  1TWH A;  5T5M D;  2VPX A;  2JIP A;  2PJH B;  3GTP A;  1Y5I A;  1KQF A;  1WLF A;  3GTG A;  5FTJ A;  1E18 A;  1PQF A;  2NVX A;  3OUG A;  1AA6 A;  1I3Q A;  1PYQ A;  1G8J A;  5EPP A;  3CQZ A;  1OGY A;  1EU1 A;  1TWA A;  1Y4Z A;  4KLN A;  4KOD A;  3TM7 B;  1CZ5 A;  1DMS A;  1IW7 D;  1SIW A; 
#chains in the Genus database with same CATH topology
 2VPZ A;  2DMR A;  2VPW A;  3HKZ A;  1YNJ D;  5C1B A;  5C18 A;  3H0G A;  1R27 A;  1YNN D;  4FER A;  2NAP A;  1G8K A;  2WAQ A;  4QIW A;  2KQA A;  2A69 D;  3CZB A;  2A68 D;  2JIR A;  4AOK B;  5FTM A;  5H4U A;  3X2L A;  1FDI A;  2Y0S A;  1Y1W A;  4CS0 A;  1SMY D;  1PPY A;  1QCS A;  2BE5 D;  2HCZ X;  1IW7 D;  2JIQ A;  3X2N A;  3X2K A;  3GTQ A;  3GTO A;  3CF2 A;  2R93 A;  2R92 A;  5DYG A;  1AW8 B;  2G5D A;  1UHD A;  2A6H D;  2PJJ A;  2PMZ A;  4JCW A;  3D30 A;  2JA7 A;  3QWZ A;  2BH0 A;  2PNW A;  4AAY A;  1SFO A;  1PQE A;  1VC3 B;  4FG2 A;  2E2H A;  3ML1 A;  5GLF A;  1OA9 A;  3DMR A;  1DMR A;  3HU2 A;  1E60 A;  1BW4 A;  2EEO B;  2CW0 D;  4ZM7 A;  3SUK A;  1R7R A;  3IR6 A;  4ENG A;  2R7Z A;  3GTL A;  1PYU B;  5DYI A;  2VPY A;  1CZ4 A;  2ENG A;  1H0H A;  1S3S A;  3IR5 A;  3X2J A;  1E32 A;  2YU9 A;  1PT1 A;  3ENG A;  1E61 A;  3TIW A;  4GA6 A;  1KQG A;  2JA5 A;  1E5V A;  1CR5 A;  2C45 A;  4AYB A;  4JP7 A;  4KDI A;  4D7Z B;  2E2I A;  3GTM A;  2JA6 A;  1R9T A;  1FDO A;  3FKI A;  4CRY G;  4GA5 A;  1H5N A;  3O5A A;  3QQ8 A;  2YUJ A;  4AON B;  4AVR A;  1Q16 A;  3QQ7 A;  1K83 A;  5FTL A;  3X2H A;  5T5I D;  2VUM A;  3M3G A;  5FTN A;  3SUJ A;  5B6C A;  2PIC A;  2NYA A;  4JJO A;  3X2G A;  2AE0 X;  1OA7 A;  2KI8 A;  4RV0 A;  3IR7 A;  1HD5 A;  4AZD A;  4NOH A;  2V45 A;  3QC8 A;  2G6G A;  4JP6 A;  2WB1 A;  1I50 A;  2JIO A;  3GTK A;  1WCM A;  2E7Z A;  2NVY A;  4L48 A;  5FTK A;  3X2O A;  1BW3 A;  4KO8 A;  5GM9 A;  4JS7 A;  2PI8 A;  4FG4 A;  5GLY A;  3HU1 A;  1TWF A;  1N10 A;  1TMO A;  2GAE A;  2V3V A;  1Y1V A;  1QDN A;  1UHE A;  5GLX A;  1TWG A;  3PLX B;  4DMR A;  1TWC A;  3HU3 A;  2B63 A;  3X2P A;  1PQH A;  1ZYR D;  3GTJ A;  4KDL A;  2IV2 X;  1YLE A;  4CRZ A;  4C2M A;  1PT0 A;  2JIM A;  1TWH A;  4FFT A;  5T5M D;  2VPX A;  2JIP A;  2PJH B;  3X2M A;  3GTP A;  1Y5I A;  1KQF A;  1WLF A;  3GTG A;  5FTJ A;  1E18 A;  1PQF A;  2NVX A;  3SUM A;  3OUG A;  3SUL A;  1AA6 A;  1I3Q A;  1WC2 A;  1PYQ A;  1ZC1 A;  1G8J A;  2A6E D;  5EPP A;  3CQZ A;  1OGY A;  3X2I A;  1EU1 A;  1TWA A;  1Y4Z A;  4KLN A;  4KOD A;  3TM7 B;  1CZ5 A;  1DMS A;  1L8F A;  2O5J D;  1SIW A; 
#chains in the Genus database with same CATH homology
 2VPZ A;  2DMR A;  2VPW A;  3HKZ A;  1YNJ D;  5C1B A;  5C18 A;  3H0G A;  1R27 A;  1YNN D;  2NAP A;  1G8K A;  2WAQ A;  4QIW A;  2A69 D;  3CZB A;  2A68 D;  2JIR A;  4AOK B;  5FTM A;  1FDI A;  2Y0S A;  1Y1W A;  4CS0 A;  1SMY D;  1PPY A;  1QCS A;  2BE5 D;  3GTQ A;  2JIQ A;  3GTO A;  3CF2 A;  2R93 A;  2R92 A;  5DYG A;  1AW8 B;  2G5D A;  1UHD A;  2A6H D;  2PJJ A;  2PMZ A;  2JA7 A;  3QWZ A;  2PNW A;  4AAY A;  1SFO A;  1PQE A;  1VC3 B;  2E2H A;  3ML1 A;  5GLF A;  3DMR A;  1DMR A;  3HU2 A;  1E60 A;  2EEO B;  2CW0 D;  1R7R A;  3IR6 A;  2R7Z A;  3GTL A;  1PYU B;  5DYI A;  2VPY A;  1CZ4 A;  1H0H A;  1S3S A;  3IR5 A;  1E32 A;  2YU9 A;  1PT1 A;  1E61 A;  3TIW A;  4GA6 A;  1KQG A;  2JA5 A;  1E5V A;  1CR5 A;  2C45 A;  4AYB A;  4KDI A;  4D7Z B;  2E2I A;  3GTM A;  2JA6 A;  1R9T A;  1FDO A;  3FKI A;  4CRY G;  4GA5 A;  1H5N A;  3O5A A;  3QQ8 A;  2YUJ A;  4AON B;  1Q16 A;  3QQ7 A;  1K83 A;  5FTL A;  2VUM A;  5T5I D;  5FTN A;  5B6C A;  2PIC A;  2NYA A;  2AE0 X;  2KI8 A;  4RV0 A;  3IR7 A;  4AZD A;  4NOH A;  2V45 A;  3QC8 A;  2G6G A;  1I50 A;  2WB1 A;  2JIO A;  3GTK A;  1WCM A;  2E7Z A;  2NVY A;  5FTK A;  4KO8 A;  2PI8 A;  3HU1 A;  1TWF A;  1TMO A;  2GAE A;  2V3V A;  1Y1V A;  1QDN A;  1UHE A;  1TWG A;  3PLX B;  4DMR A;  1TWC A;  3HU3 A;  2B63 A;  1PQH A;  1ZYR D;  3GTJ A;  4KDL A;  2IV2 X;  1YLE A;  4CRZ A;  4C2M A;  1PT0 A;  2JIM A;  1TWH A;  5T5M D;  2VPX A;  2JIP A;  2PJH B;  3GTP A;  1Y5I A;  1KQF A;  1WLF A;  3GTG A;  5FTJ A;  1E18 A;  1PQF A;  2NVX A;  3OUG A;  1AA6 A;  1I3Q A;  1PYQ A;  1ZC1 A;  1G8J A;  2A6E D;  5EPP A;  3CQZ A;  1OGY A;  1EU1 A;  1TWA A;  1Y4Z A;  4KLN A;  4KOD A;  3TM7 B;  1CZ5 A;  1DMS A;  1IW7 D;  2O5J D;  1SIW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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