4AONB

Conformational dynamics of aspartate alpha-decarboxylase active site revealed by protein-ligand complexes: 1-methyl-l-aspartate complex
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
97
structure length
97
Chain Sequence
CAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Dynamics of Aspartate Alpha Decarboxylase Active Site Revealed by Protein-Ligand Complexes
rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords ASPARTATE-ALPHA-DECARBOXYLASE BETA CHAIN
total genus 23
structure length 97
sequence length 97
chains with identical sequence E
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2012-03-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4aonB00
1TWGA 2EEOB 1I3QA 4CS0A 2JA7A 1R7RA 3GTOA 3GTJA 4CRZA 4D7ZB 3TM7B 4KLNA 4GA5A 1Y4ZA 4AONB 1R9TA 4AZDA 4QIWA 1DMSA 1Y1WA 3QWZA 5FTJA 1E18A 3IR6A 3ML1A 3GTKA 2PMZA 1PYUB 1I50A 2Y0SA 1PPYA 1Q16A 1PQFA 4KDLA 1SIWA 5C1BA 1TWAA 4KDIA 1EU1A 4DMRA 4GA6A 2R7ZA 2E7ZA 1FDOA 5C18A 1E61A 3H0GA 2JIMA 1G8KA 1WLFA 2JA6A 5B6CA 1KQFA 2VPXA 4AAYA 1K83A 2VUMA 2VPWA 1UHEA 1S3SA 3TIWA 1KQGA 3GTGA 3QQ8A 2IV2X 2B63A 4AYBA 1OGYA 2JA5A 1E32A 5FTMA 1CR5A 1TMOA 5FTLA 2NVYA 1FDIA 5EPPA 1SFOA 5T5ID 1PT1A 3OUGA 2WAQA 1TWHA 2JIQA 1VC3B 3IR5A 3HU3A 1AA6A 1QDNA 2JIRA 3PLXB 3FKIA 1E60A 1Y5IA 2VPZA 3GTLA 2YU9A 5FTKA 2R93A 2E2HA 5DYIA 3QC8A 2V3VA 3CF2A 2R92A 4KODA 1TWCA 5DYGA 1YLEA 5GLFA 2NYAA 3HU1A 1H5NA 5T5MD 1QCSA 4CRYG 2JIPA 1R27A 3HU2A 2PJHB 3IR7A 2JIOA 1UHDA 4KO8A 4C2MA 3QQ7A 5FTNA 4RV0A 1CZ4A 2NAPA 3GTMA 1PT0A 1E5VA 4AOKB 3GTQA 3GTPA 2V45A 1IW7D 1TWFA 1AW8B 3O5AA 3HKZA 3CQZA 1PQHA 1Y1VA 1PQEA 1PYQA 1G8JA 2C45A 3DMRA 1DMRA 1CZ5A 2E2IA 1WCMA 2DMRA 2VPYA 2NVXA 1H0HA 2KI8A 2WB1A
chains in the Genus database with same CATH superfamily
3X2LA 2G6GA 3X2MA 2ENGA 3CZBA 1TWGA 2EEOB 1I3QA 3X2KA 4CS0A 2JA7A 1R7RA 3GTOA 3GTJA 4CRZA 5GM9A 4D7ZB 3TM7B 4KLNA 1YNND 4GA5A 1Y4ZA 4AONB 1R9TA 4AZDA 4QIWA 4JCWA 1DMSA 1N10A 1Y1WA 3X2NA 3QWZA 5FTJA 1E18A 3IR6A 3ML1A 3GTKA 4FERA 2HCZX 2PMZA 1PYUB 4FFTA 1I50A 5GLYA 2Y0SA 1PPYA 1OA7A 1PQFA 1Q16A 4KDLA 1BW4A 1SIWA 2G5DA 3SUJA 5C1BA 1TWAA 4KDIA 1EU1A 4DMRA 3X2GA 4GA6A 2R7ZA 4NOHA 2E7ZA 3SUMA 1FDOA 5C18A 1E61A 3H0GA 2A68D 4FG4A 4JP6A 4ENGA 2JIMA 2AE0X 1G8KA 1WLFA 2BE5D 4JS7A 2JA6A 1BW3A 5B6CA 1KQFA 4AAYA 1K83A 2VUMA 2VPWA 4FG2A 1HD5A 1UHEA 1S3SA 3TIWA 1KQGA 3GTGA 4JJOA 3QQ8A 2IV2X 1ZC1A 1ZYRD 4AYBA 2B63A 3X2JA 1OGYA 1WC2A 2A6ED 3M3GA 3SUKA 2JA5A 1E32A 5FTMA 1CR5A 1TMOA 5FTLA 2NVYA 5H4UA 2PNWA 1FDIA 5EPPA 1SFOA 3ENGA 5T5ID 1PT1A 1SMYD 3OUGA 2WAQA 1TWHA 3X2HA 2JIQA 1VC3B 3IR5A 3HU3A 1AA6A 2A6HD 1QDNA 2JIRA 2GAEA 3FKIA 2WB1A 3PLXB 1E60A 1Y5IA 2VPZA 3GTLA 2YU9A 5FTKA 3X2PA 2R93A 2E2HA 5DYIA 2PJJA 3QC8A 2V3VA 3CF2A 2R92A 4KODA 1TWCA 2PI8A 5DYGA 1OA9A 1YLEA 5GLFA 4AVRA 2NYAA 3HU1A 1L8FA 1H5NA 5T5MD 1QCSA 4CRYG 1R27A 2JIPA 3HU2A 2YUJA 3X2OA 2A69D 2PJHB 3IR7A 2JIOA 1UHDA 4KO8A 4C2MA 3QQ7A 5FTNA 4RV0A 1CZ4A 2O5JD 2NAPA 3GTMA 1PT0A 1YNJD 2CW0D 2KQAA 1E5VA 4ZM7A 3D30A 4AOKB 3GTQA 3GTPA 2V45A 1IW7D 1TWFA 1AW8B 2BH0A 3HKZA 3O5AA 3X2IA 3CQZA 1PQHA 1Y1VA 1PQEA 2PICA 1PYQA 4L48A 1G8JA 2C45A 3DMRA 1DMRA 1CZ5A 3SULA 2E2IA 1WCMA 2DMRA 5GLXA 2VPYA 2NVXA 1H0HA 2KI8A 2VPXA 4JP7A
chains in the Genus database with same CATH topology
2G6GA 3CZBA 1TWGA 2EEOB 1I3QA 4CS0A 2JA7A 1R7RA 3GTOA 3GTJA 4CRZA 4D7ZB 3TM7B 4KLNA 1YNND 4GA5A 1Y4ZA 4AONB 1R9TA 4AZDA 4QIWA 1DMSA 1Y1WA 3QWZA 5FTJA 1E18A 3IR6A 3ML1A 3GTKA 2PMZA 1PYUB 1I50A 2Y0SA 1PPYA 1Q16A 1PQFA 4KDLA 1SIWA 2G5DA 5C1BA 1TWAA 4KDIA 1EU1A 4DMRA 4GA6A 2R7ZA 4NOHA 2E7ZA 1FDOA 5C18A 1E61A 3H0GA 2A68D 2JIMA 2AE0X 1G8KA 1WLFA 2BE5D 2JA6A 5B6CA 1KQFA 4AAYA 1K83A 2VUMA 2VPWA 1UHEA 1S3SA 3TIWA 1KQGA 3GTGA 3QQ8A 2IV2X 1ZC1A 1ZYRD 4AYBA 2B63A 1OGYA 2A6ED 2JA5A 1E32A 5FTMA 1CR5A 1TMOA 5FTLA 2NVYA 2PNWA 1FDIA 5EPPA 1SFOA 5T5ID 1PT1A 1SMYD 3OUGA 2WAQA 1TWHA 2JIQA 1VC3B 3IR5A 3HU3A 1AA6A 2A6HD 1QDNA 2JIRA 2GAEA 3FKIA 2WB1A 3PLXB 1E60A 1Y5IA 2VPZA 3GTLA 2YU9A 5FTKA 2R93A 2E2HA 5DYIA 2PJJA 3QC8A 2V3VA 3CF2A 2R92A 4KODA 1TWCA 2PI8A 5DYGA 1YLEA 5GLFA 2NYAA 3HU1A 1H5NA 5T5MD 1QCSA 4CRYG 2JIPA 1R27A 3HU2A 2YUJA 2A69D 2PJHB 3IR7A 2JIOA 1UHDA 4KO8A 4C2MA 3QQ7A 5FTNA 4RV0A 1CZ4A 2O5JD 2NAPA 3GTMA 1PT0A 1YNJD 2CW0D 1E5VA 4AOKB 3GTQA 3GTPA 2V45A 1IW7D 1TWFA 1AW8B 3O5AA 3HKZA 3CQZA 1PQHA 1Y1VA 1PQEA 2PICA 1PYQA 1G8JA 2C45A 3DMRA 1DMRA 1CZ5A 2E2IA 1WCMA 2DMRA 2VPYA 2NVXA 1H0HA 2KI8A 2VPXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TWG A;  2EEO B;  1I3Q A;  4CS0 A;  2JA7 A;  1R7R A;  3GTO A;  3GTJ A;  4CRZ A;  4D7Z B;  3TM7 B;  4KLN A;  4GA5 A;  1Y4Z A;  4AON B;  1R9T A;  4AZD A;  4QIW A;  1DMS A;  1Y1W A;  3QWZ A;  5FTJ A;  1E18 A;  3IR6 A;  3ML1 A;  3GTK A;  2PMZ A;  1PYU B;  1I50 A;  2Y0S A;  1PPY A;  1Q16 A;  1PQF A;  4KDL A;  1SIW A;  5C1B A;  1TWA A;  4KDI A;  1EU1 A;  4DMR A;  4GA6 A;  2R7Z A;  2E7Z A;  1FDO A;  5C18 A;  1E61 A;  3H0G A;  2JIM A;  1G8K A;  1WLF A;  2JA6 A;  5B6C A;  1KQF A;  2VPX A;  4AAY A;  1K83 A;  2VUM A;  2VPW A;  1UHE A;  1S3S A;  3TIW A;  1KQG A;  3GTG A;  3QQ8 A;  2IV2 X;  2B63 A;  4AYB A;  1OGY A;  2JA5 A;  1E32 A;  5FTM A;  1CR5 A;  1TMO A;  5FTL A;  2NVY A;  1FDI A;  5EPP A;  1SFO A;  5T5I D;  1PT1 A;  3OUG A;  2WAQ A;  1TWH A;  2JIQ A;  1VC3 B;  3IR5 A;  3HU3 A;  1AA6 A;  1QDN A;  2JIR A;  3PLX B;  3FKI A;  1E60 A;  1Y5I A;  2VPZ A;  3GTL A;  2YU9 A;  5FTK A;  2R93 A;  2E2H A;  5DYI A;  3QC8 A;  2V3V A;  3CF2 A;  2R92 A;  4KOD A;  1TWC A;  5DYG A;  1YLE A;  5GLF A;  2NYA A;  3HU1 A;  1H5N A;  5T5M D;  1QCS A;  4CRY G;  2JIP A;  1R27 A;  3HU2 A;  2PJH B;  3IR7 A;  2JIO A;  1UHD A;  4KO8 A;  4C2M A;  3QQ7 A;  5FTN A;  4RV0 A;  1CZ4 A;  2NAP A;  3GTM A;  1PT0 A;  1E5V A;  4AOK B;  3GTQ A;  3GTP A;  2V45 A;  1IW7 D;  1TWF A;  1AW8 B;  3O5A A;  3HKZ A;  3CQZ A;  1PQH A;  1Y1V A;  1PQE A;  1PYQ A;  1G8J A;  2C45 A;  3DMR A;  1DMR A;  1CZ5 A;  2E2I A;  1WCM A;  2DMR A;  2VPY A;  2NVX A;  1H0H A;  2KI8 A;  2WB1 A; 
#chains in the Genus database with same CATH topology
 3X2L A;  2G6G A;  3X2M A;  2ENG A;  3CZB A;  1TWG A;  2EEO B;  1I3Q A;  3X2K A;  4CS0 A;  2JA7 A;  1R7R A;  3GTO A;  3GTJ A;  4CRZ A;  5GM9 A;  4D7Z B;  3TM7 B;  4KLN A;  1YNN D;  4GA5 A;  1Y4Z A;  4AON B;  1R9T A;  4AZD A;  4QIW A;  4JCW A;  1DMS A;  1N10 A;  1Y1W A;  3X2N A;  3QWZ A;  5FTJ A;  1E18 A;  3IR6 A;  3ML1 A;  3GTK A;  4FER A;  2HCZ X;  2PMZ A;  1PYU B;  4FFT A;  1I50 A;  5GLY A;  2Y0S A;  1PPY A;  1OA7 A;  1PQF A;  1Q16 A;  4KDL A;  1BW4 A;  1SIW A;  2G5D A;  3SUJ A;  5C1B A;  1TWA A;  4KDI A;  1EU1 A;  4DMR A;  3X2G A;  4GA6 A;  2R7Z A;  4NOH A;  2E7Z A;  3SUM A;  1FDO A;  5C18 A;  1E61 A;  3H0G A;  2A68 D;  4FG4 A;  4JP6 A;  4ENG A;  2JIM A;  2AE0 X;  1G8K A;  1WLF A;  2BE5 D;  4JS7 A;  2JA6 A;  1BW3 A;  5B6C A;  1KQF A;  4AAY A;  1K83 A;  2VUM A;  2VPW A;  4FG2 A;  1HD5 A;  1UHE A;  1S3S A;  3TIW A;  1KQG A;  3GTG A;  4JJO A;  3QQ8 A;  2IV2 X;  1ZC1 A;  1ZYR D;  4AYB A;  2B63 A;  3X2J A;  1OGY A;  1WC2 A;  2A6E D;  3M3G A;  3SUK A;  2JA5 A;  1E32 A;  5FTM A;  1CR5 A;  1TMO A;  5FTL A;  2NVY A;  5H4U A;  2PNW A;  1FDI A;  5EPP A;  1SFO A;  3ENG A;  5T5I D;  1PT1 A;  1SMY D;  3OUG A;  2WAQ A;  1TWH A;  3X2H A;  2JIQ A;  1VC3 B;  3IR5 A;  3HU3 A;  1AA6 A;  2A6H D;  1QDN A;  2JIR A;  2GAE A;  3FKI A;  2WB1 A;  3PLX B;  1E60 A;  1Y5I A;  2VPZ A;  3GTL A;  2YU9 A;  5FTK A;  3X2P A;  2R93 A;  2E2H A;  5DYI A;  2PJJ A;  3QC8 A;  2V3V A;  3CF2 A;  2R92 A;  4KOD A;  1TWC A;  2PI8 A;  5DYG A;  1OA9 A;  1YLE A;  5GLF A;  4AVR A;  2NYA A;  3HU1 A;  1L8F A;  1H5N A;  5T5M D;  1QCS A;  4CRY G;  1R27 A;  2JIP A;  3HU2 A;  2YUJ A;  3X2O A;  2A69 D;  2PJH B;  3IR7 A;  2JIO A;  1UHD A;  4KO8 A;  4C2M A;  3QQ7 A;  5FTN A;  4RV0 A;  1CZ4 A;  2O5J D;  2NAP A;  3GTM A;  1PT0 A;  1YNJ D;  2CW0 D;  2KQA A;  1E5V A;  4ZM7 A;  3D30 A;  4AOK B;  3GTQ A;  3GTP A;  2V45 A;  1IW7 D;  1TWF A;  1AW8 B;  2BH0 A;  3HKZ A;  3O5A A;  3X2I A;  3CQZ A;  1PQH A;  1Y1V A;  1PQE A;  2PIC A;  1PYQ A;  4L48 A;  1G8J A;  2C45 A;  3DMR A;  1DMR A;  1CZ5 A;  3SUL A;  2E2I A;  1WCM A;  2DMR A;  5GLX A;  2VPY A;  2NVX A;  1H0H A;  2KI8 A;  2VPX A;  4JP7 A; 
#chains in the Genus database with same CATH homology
 2G6G A;  3CZB A;  1TWG A;  2EEO B;  1I3Q A;  4CS0 A;  2JA7 A;  1R7R A;  3GTO A;  3GTJ A;  4CRZ A;  4D7Z B;  3TM7 B;  4KLN A;  1YNN D;  4GA5 A;  1Y4Z A;  4AON B;  1R9T A;  4AZD A;  4QIW A;  1DMS A;  1Y1W A;  3QWZ A;  5FTJ A;  1E18 A;  3IR6 A;  3ML1 A;  3GTK A;  2PMZ A;  1PYU B;  1I50 A;  2Y0S A;  1PPY A;  1Q16 A;  1PQF A;  4KDL A;  1SIW A;  2G5D A;  5C1B A;  1TWA A;  4KDI A;  1EU1 A;  4DMR A;  4GA6 A;  2R7Z A;  4NOH A;  2E7Z A;  1FDO A;  5C18 A;  1E61 A;  3H0G A;  2A68 D;  2JIM A;  2AE0 X;  1G8K A;  1WLF A;  2BE5 D;  2JA6 A;  5B6C A;  1KQF A;  4AAY A;  1K83 A;  2VUM A;  2VPW A;  1UHE A;  1S3S A;  3TIW A;  1KQG A;  3GTG A;  3QQ8 A;  2IV2 X;  1ZC1 A;  1ZYR D;  4AYB A;  2B63 A;  1OGY A;  2A6E D;  2JA5 A;  1E32 A;  5FTM A;  1CR5 A;  1TMO A;  5FTL A;  2NVY A;  2PNW A;  1FDI A;  5EPP A;  1SFO A;  5T5I D;  1PT1 A;  1SMY D;  3OUG A;  2WAQ A;  1TWH A;  2JIQ A;  1VC3 B;  3IR5 A;  3HU3 A;  1AA6 A;  2A6H D;  1QDN A;  2JIR A;  2GAE A;  3FKI A;  2WB1 A;  3PLX B;  1E60 A;  1Y5I A;  2VPZ A;  3GTL A;  2YU9 A;  5FTK A;  2R93 A;  2E2H A;  5DYI A;  2PJJ A;  3QC8 A;  2V3V A;  3CF2 A;  2R92 A;  4KOD A;  1TWC A;  2PI8 A;  5DYG A;  1YLE A;  5GLF A;  2NYA A;  3HU1 A;  1H5N A;  5T5M D;  1QCS A;  4CRY G;  2JIP A;  1R27 A;  3HU2 A;  2YUJ A;  2A69 D;  2PJH B;  3IR7 A;  2JIO A;  1UHD A;  4KO8 A;  4C2M A;  3QQ7 A;  5FTN A;  4RV0 A;  1CZ4 A;  2O5J D;  2NAP A;  3GTM A;  1PT0 A;  1YNJ D;  2CW0 D;  1E5V A;  4AOK B;  3GTQ A;  3GTP A;  2V45 A;  1IW7 D;  1TWF A;  1AW8 B;  3O5A A;  3HKZ A;  3CQZ A;  1PQH A;  1Y1V A;  1PQE A;  2PIC A;  1PYQ A;  1G8J A;  2C45 A;  3DMR A;  1DMR A;  1CZ5 A;  2E2I A;  1WCM A;  2DMR A;  2VPY A;  2NVX A;  1H0H A;  2KI8 A;  2VPX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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