4BTIA

Factor xa in complex with the dual thrombin-fxa inhibitor 58.
Total Genus 10
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 5-Chlorothiophene-2-Carboxylic Acid [(S)-2-[2-Methyl-3-(2-Oxopyrrolidin-1-Yl)Benzenesulfonylamino]-3-(4-Methylpiperazin-1-Yl)-3-Oxopropyl]Amide (Sar107375), a Selective and Potent Orally Active Dual Thrombin and Factor Xa Inhibitor.
pubmed doi rcsb
molecule keywords COAGULATION FACTOR X HEAVY CHAIN
molecule tags Hydrolase
total genus 10
structure length 53
sequence length 53
chains with identical sequence E
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2013-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00008 EGF EGF-like domain
A PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 4btiA00
2XC5L 1B9WA 3N8WA 2WPHE 3GISX 3KL6B 1JV2B 2VVCK 3TK5B 2G00L 2FLBL 1PGEA 1UZQA 3TZIA 5IKRA 1FSBA 2Y5HL 1IQFL 4JYVL 3V64C 1C5MF 1G1TA 2WPJE 3KQBL 2J34B 5COXA 4A7IA 4O02B 4CUFA 1UZJA 3ZYIB 3C9AC 1CCVA 1IGXA 2XBXL 4BDWA 5F1AA 3SOBB 2W86A 4Y76B 2F9BL 3SOVA 3NT1A 1P9JA 3HS6A 1EMNA 2BQWA 3HO3A 3CENL 4X8UL 1PTHA 3TK6B 1NT0A 2P3TA 1CX2A 3SOQA 1IQNL 1XKAL 2EI7B 5IKQA 4G1MB 1U8CB 1PRHA 1YO8A 4Z0KB 3KQDL 2RHPA 2J95B 3KQEL 1DVAL 4CSYA 4ZHAB 4AQTA 2P3UA 5JB8E 1YGCL 1W7XL 2VH0B 1LPZA 3PGHA 1ATDA 5L2ZL 3MDLA 1KLOA 4E1GA 4Z0LA 1CQEA 5KN5C 4COXA 1IQHL 2OYUP 1W8BL 4RRZA 3M36L 2PUQL 4BXWA 4C16A 2J94B 5JB9E 4X8SL 1APQA 2P93L 2MGRA 2GD4A 3KCGL 3U73A 2VWLL 1F0SB 3BT1A 2Y82B 1HT8A 2WG3C 1IQML 3HS7A 3OLUA 3LTFB 2BOKL 1V3XB 3TGFA 3LN1A 1RFNB 4ZXXL 3KQCL 2KV4A 3LC5B 1LPKA 1DX5I 4YT7L 1ADXA 1HX2A 1IQJL 1KIGL 2P28B 4M11A 1JBUL 4ISHL 1IGZA 4BDXA 3HO5A 5CKMA 1EQHA 1K36A 1NFXB 1Z6CA 3FBYA 1TOZA 4JZEL 5L2YL 4BXSA 1YUKB 2DDUA 2P3FL 4BTIA 2XBWL 4NG9L 1LPGA 3BPSE 1WHFA 5L30L 2VJ3A 1FAKL 1DDXA 1MQ6L 1MOXC 2VVUL 1CEJA 2BO2A 1M1XB 4Y6DB 1IQEL 1JL9A 2P26A 1A3PA 4LMFA 2P3FN 4M10A 2BMGA 5IKTA 3RR3A 4OTYA 3QCWA 1FE2A 4ZH8B 3QH0A 5CKNA 3FCSB 3M37L 1YUFA 1EPIA 2UWPB 1IQKL 3EGFA 1PXXA 5EGMB 3DEMA 3N8VA 3ZYJB 2YGPA 1G1RA 2WPME 4MMZB 1EZQB 1HAFA 1KLIL 2WYJB 2P94L 3LAQA 1EBVA 4RRXA 3NTGA 6COXA 1G1QA 4Y71B 1PFXL 1G2MB 2VWNL 2W3IB 5JBAE 1HZ8A 1L3YA 1X7AL 3F1SB 2J38B 3HS5A 2FZZL 1IQLL 1N1IA 1IQGL 2PHBB 1HREA 1EPHA 2CJIB 4JZFL 1EPJA 2XBYL 4RRYA 4ZAEB 1HCGB 3ZYGA 3CS7L 1FFMA 4JYUL 4Y7BB 1DQBA 3TH3L 1P0SL 2J4IB 1N7DA 5KIRA 4RS0A 1CVWL 1IP0A 1NFWB 2EI8B 3V65B 2K2SB 4RRWA 2K2TA 1IVOC 3H5CB 2Y81B 1IOEL 3N8YB 4TGFA 4MMXB 5CKQA 4PH9A 2I9AA 2Y7ZB 2EI6B 2VWOL 2WFXB 1GK5A 1NFYB 1YUGA 3IJEB 1ATEA 2W26B 1EGFA 4Y79B 1EAIC 2XBVL 2Y5GL 1F7MA 3LC3B 3MQEA 2WYGB 1CVUA 4XL1A 1APOA 4CUEA 2P95L 1EMOA 4O1ZA 2OYEP 4RUTA 4BTUA 3HO4A 4MMYB 4X8VL 2VH6B 1COUA 2Y5FL 4YT6L 1F7EA 1K37A 2BOHA 1EQGA 3QMOA 2I9BA 4NA9L 3ELAL 1J9CL 1EPGA 3IITB 2D1JB 2WPIE 1KSNB 2VWMK 5I46L 5JVZA 2UWLB 4X8TL 1MQ5L 1IQIL 2JKHL 1O5DL 4BTTA 3U7UG 3ASIA 5JBCE 4Y7AB 1SZBA 2W2NE 2W2ME 3GCWE 3LN0A 1ATAA 1G1SA 4D0EA 1IJQA 2RNLA 3NJPC 1HT5A 1CCFA 2W2OE 3F6UL 3N8WB 4ISIL 2WPKE 4YZUB 2Y38A 4D90A 1URKA 2BQ7A 2MGPA 2B7DL 4JZDL 3P5BL 3TBDA 1IOXA 1OB1C 2BQ6A 1L5GB 5E8DA 1BF9A 1XFEA 5JBBE 1NFUB 2NPRA 2W2QE 4FM5A 2H9EL 1LMJA 3BT2A 2UWOB 2M74A 2PR3B 1LQDA 3FFGL 5K0HB 1I0UA 1HRFA 1XDTR 3N8XA 2TGFA 3KK6A 2AYLA 5JVYA 1Z6EL 1WHEA 1TLEA 3N8ZA 3Q7DA 2VVVL 4ZXYL 3SW2A 5CISA 5F19A 1NZIA 1TPGA 2W3KB 3CA7A 4XLWA 1ATBA 2ADXA 2WPLE 1HJ7A 1ZAQA 3N8YA 3CFWA 2J2UB 2WFTA 2XC0L 1F0RB 1QFKL 2BZ6L 2FLGA 1NPEB 2YGOA 2MHPA 3ENSA 2P16L 3LTGD 3R05A 2KB9A 3POYA 4D0FA 3LIWB 4NGAL 1DIYA 1WU1B 3KRKA 4CUDA 2Y7XB 1KLJL 1FAXL 1Q4GA 2RA0L 5FDQA 2BOXA 2W2PE 4LORA 1G2LB 1FF7A 4XBMA 1UZPA 2FD6A 2WG4B 5IKVA 2FLRL 2Y80B 1HAEA 1UZKA 1AUTL 3GCXE 1NQLB 4Z6AL 3K9XA 1FJSL 5JW1A 3NTBA 2Q1JB 2KL7A 3HPTA 4OTJA 2XC4L 3OLTA 1U67A 2BOUA 1XKBA 3Q3KB
chains in the Genus database with same CATH superfamily
2XC5L 1B9WA 3N8WA 2WPHE 3GISX 3KL6B 1JV2B 2VVCK 3TK5B 2G00L 2FLBL 2HORA 1PGEA 1UZQA 3TZIA 5IKRA 1FSBA 2Y5HL 1IQFL 4JYVL 3V64C 1C5MF 1G1TA 2WPJE 3KQBL 2J34B 5COXA 4A7IA 4O02B 4CUFA 1UZJA 3ZYIB 3C9AC 1CCVA 1IGXA 2XBXL 4BDWA 5F1AA 3SOBB 4GU3A 2W86A 4Y76B 2F9BL 3SOVA 3NT1A 1P9JA 3HS6A 1EMNA 2BQWA 3HO3A 3CENL 4X8UL 1PTHA 3TK6B 1NT0A 2P3TA 2BT7A 1CX2A 3SOQA 1IQNL 1XKAL 2EI7B 5IKQA 4G1MB 1U8CB 1PRHA 2VRSA 1YO8A 4Z0KB 3KQDL 2RHPA 2J95B 3KQEL 1DVAL 4CSYA 4ZHAB 4AQTA 2P3UA 5JB8E 1YGCL 1W7XL 2VH0B 1LPZA 3PGHA 1ATDA 5L2ZL 3MDLA 4A94C 1KLOA 4E1GA 4Z0LA 1LMMA 1CQEA 5KN5C 4COXA 1IQHL 2OYUP 1W8BL 4RRZA 3M36L 2PUQL 4BXWA 4C16A 2J94B 5JB9E 4X8SL 1APQA 2P93L 2MGRA 2GD4A 3KCGL 2WZPP 2VWLL 3U73A 1F0SB 3BT1A 2Y82B 1HT8A 2WG3C 1IQML 3HS7A 3OLUA 1QIUA 3LTFB 2BOKL 1V3XB 3TGFA 3LN1A 1RFNB 1V1IA 3KQCL 4ZXXL 2KV4A 3LC5B 1LPKA 1DX5I 4YT7L 1ADXA 1HX2A 1IQJL 1KIGL 2P28B 4M11A 1JBUL 4ISHL 2KNIA 1IGZA 4BDXA 3HO5A 5CKMA 1EQHA 1K36A 1NFXB 1Z6CA 2BT8A 3FBYA 1TOZA 4JZEL 5L2YL 4BXSA 1YUKB 2DDUA 2P3FL 4BTIA 2XBWL 4NG9L 1LPGA 2YGQA 3BPSE 1WHFA 5L30L 2VJ3A 1FAKL 1DDXA 1MQ6L 1MOXC 1LK9A 2VVUL 1CEJA 2BO2A 1M1XB 4Y6DB 1IQEL 1JL9A 2P26A 1A3PA 4LMFA 2P3FN 4M10A 2BMGA 5IKTA 3RR3A 4OTYA 3QCWA 1FE2A 4ZH8B 3QH0A 5CKNA 3FCSB 3M37L 1YUFA 1EPIA 2UWPB 1IQKL 3EGFA 1PXXA 5EGMB 3DEMA 3N8VA 3ZYJB 2YGPA 1G1RA 2WPME 4MMZB 1EZQB 1HAFA 1KLIL 2WYJB 2P94L 3LAQA 1EBVA 2BSFA 4RRXA 3NTGA 6COXA 1G1QA 4Y71B 1PFXL 1G2MB 2VWNL 2W3IB 5JBAE 1HZ8A 1L3YA 1X7AL 3F1SB 2J38B 3HS5A 2FZZL 1IQLL 1N1IA 1IQGL 2PHBB 1HREA 1EPHA 2H9EC 2CJIB 4JZFL 1EPJA 2XBYL 4RRYA 4ZAEB 1HCGB 3ZYGA 3CS7L 1FFMA 4JYUL 4Y7BB 1DQBA 3TH3L 1P0SL 2J4IB 1N7DA 5KIRA 4RS0A 1CVWL 1IP0A 1NFWB 2EI8B 3V65B 2K2SB 4RRWA 2K2TA 1IVOC 3H5CB 2Y81B 1IOEL 3N8YB 4TGFA 4MMXB 5CKQA 4PH9A 2I9AA 2Y7ZB 2EI6B 2VWOL 2WFXB 1GK5A 1NFYB 1YUGA 3IJEB 1ATEA 2W26B 1EGFA 4Y79B 1EAIC 2XBVL 2Y5GL 1F7MA 3LC3B 3MQEA 2WYGB 1CVUA 4XL1A 1APOA 4CUEA 2P95L 1EMOA 4O1ZA 2OYEP 4RUTA 4BTUA 3HO4A 4MMYB 4X8VL 2VH6B 1COUA 2Y5FL 4YT6L 1F7EA 1K37A 2BOHA 1EQGA 3QMOA 2I9BA 4NA9L 3ELAL 1J9CL 1EPGA 2HOXA 3IITB 2D1JB 2WPIE 1KSNB 2VWMK 5I46L 5JVZA 3S6XA 2UWLB 4X8TL 4GU4A 1MQ5L 1IQIL 2JKHL 1O5DL 4BTTA 3U7UG 3ASIA 5JBCE 4Y7AB 1SZBA 2W2NE 2W2ME 3GCWE 3LN0A 1ATAA 1G1SA 4D0EA 1IJQA 2RNLA 3NJPC 1HT5A 1CCFA 2W2OE 3F6UL 3N8WB 4ISIL 2WPKE 4YZUB 2Y38A 4D90A 1URKA 2BQ7A 2MGPA 2B7DL 4JZDL 3P5BL 3TBDA 1IOXA 1OB1C 2BQ6A 1L5GB 5E8DA 1BF9A 1XFEA 5JBBE 1NFUB 2NPRA 2W2QE 4FM5A 2H9EL 1LMJA 3BT2A 2UWOB 2M74A 1KKEA 2PR3B 1LQDA 3FFGL 5K0HB 1I0UA 1HRFA 1XDTR 3N8XA 2TGFA 3KK6A 2AYLA 5JVYA 1Z6EL 1WHEA 1TLEA 3N8ZA 3Q7DA 2VVVL 4ZXYL 3SW2A 5CISA 5F19A 1NZIA 1TPGA 2W3KB 3CA7A 4XLWA 1ATBA 2ADXA 2JJLA 2WPLE 1HJ7A 1ZAQA 3N8YA 3CFWA 2J2UB 2WFTA 2XC0L 1V1HA 1F0RB 1QFKL 2BZ6L 2FLGA 1NPEB 2YGOA 2MHPA 3ENSA 2P16L 3LTGD 3R05A 2KB9A 3POYA 4D0FA 3LIWB 4NGAL 1DIYA 1WU1B 3KRKA 4CUDA 2Y7XB 1KLJL 1FAXL 1Q4GA 2RA0L 5FDQA 2BOXA 2W2PE 4LORA 1G2LB 1FF7A 4XBMA 1UZPA 2FD6A 2WG4B 5IKVA 2FLRL 2Y80B 1HAEA 1UZKA 1AUTL 3GCXE 1NQLB 4Z6AL 3K9XA 1FJSL 5JW1A 3NTBA 2Q1JB 2KL7A 3HPTA 4OTJA 2XC4L 3OLTA 1U67A 2BOUA 1XKBA 3Q3KB
chains in the Genus database with same CATH topology
2XC5L 1B9WA 3N8WA 2WPHE 3GISX 3KL6B 1JV2B 2VVCK 3TK5B 2G00L 2FLBL 1PGEA 1UZQA 3TZIA 5IKRA 1FSBA 2Y5HL 1IQFL 4JYVL 3V64C 1C5MF 1G1TA 2WPJE 3KQBL 2J34B 5COXA 4A7IA 4O02B 4CUFA 1UZJA 3ZYIB 3C9AC 1CCVA 1IGXA 2XBXL 4BDWA 5F1AA 3SOBB 2W86A 4Y76B 2F9BL 3SOVA 3NT1A 1P9JA 3HS6A 1EMNA 2BQWA 3HO3A 3CENL 4X8UL 1PTHA 3TK6B 1NT0A 2P3TA 1CX2A 3SOQA 1IQNL 1XKAL 2EI7B 5IKQA 4G1MB 1U8CB 1PRHA 1YO8A 4Z0KB 3KQDL 2RHPA 2J95B 3KQEL 1DVAL 4CSYA 4ZHAB 4AQTA 2P3UA 5JB8E 1YGCL 1W7XL 2VH0B 1LPZA 3PGHA 1ATDA 5L2ZL 3MDLA 4A94C 1KLOA 4E1GA 4Z0LA 1LMMA 1CQEA 5KN5C 4COXA 1IQHL 2OYUP 1W8BL 4RRZA 3M36L 2PUQL 4BXWA 4C16A 2J94B 5JB9E 4X8SL 1APQA 2P93L 2MGRA 2GD4A 3KCGL 2WZPP 2VWLL 3U73A 1F0SB 3BT1A 2Y82B 1HT8A 2WG3C 1IQML 3HS7A 3OLUA 3LTFB 2BOKL 1V3XB 3TGFA 3LN1A 1RFNB 4ZXXL 3KQCL 2KV4A 3LC5B 1LPKA 1DX5I 4YT7L 1ADXA 1HX2A 1IQJL 1KIGL 2P28B 4M11A 1JBUL 4ISHL 2KNIA 1IGZA 4BDXA 3HO5A 5CKMA 1EQHA 1K36A 1NFXB 1Z6CA 3FBYA 1TOZA 4JZEL 5L2YL 4BXSA 1YUKB 2DDUA 2P3FL 4BTIA 2XBWL 4NG9L 1LPGA 2YGQA 3BPSE 1WHFA 5L30L 2VJ3A 1FAKL 1DDXA 1MQ6L 1MOXC 2VVUL 1CEJA 2BO2A 1M1XB 4Y6DB 1IQEL 1JL9A 2P26A 1A3PA 4LMFA 2P3FN 4M10A 2BMGA 5IKTA 3RR3A 4OTYA 3QCWA 1FE2A 4ZH8B 3QH0A 5CKNA 3FCSB 3M37L 1YUFA 1EPIA 2UWPB 1IQKL 3EGFA 1PXXA 5EGMB 3DEMA 3N8VA 3ZYJB 2YGPA 1G1RA 2WPME 4MMZB 1EZQB 1HAFA 1KLIL 2WYJB 2P94L 3LAQA 1EBVA 4RRXA 3NTGA 6COXA 1G1QA 4Y71B 1PFXL 1G2MB 2VWNL 2W3IB 5JBAE 1HZ8A 1L3YA 1X7AL 3F1SB 2J38B 3HS5A 2FZZL 1IQLL 1N1IA 1IQGL 2PHBB 1HREA 1EPHA 2H9EC 2CJIB 4JZFL 1EPJA 2XBYL 4RRYA 4ZAEB 1HCGB 3ZYGA 3CS7L 1FFMA 4JYUL 4Y7BB 1DQBA 3TH3L 1P0SL 2J4IB 1N7DA 5KIRA 4RS0A 1CVWL 1IP0A 1NFWB 2EI8B 3V65B 2K2SB 4RRWA 2K2TA 1IVOC 3H5CB 2Y81B 1IOEL 3N8YB 4TGFA 4MMXB 5CKQA 4PH9A 2I9AA 2Y7ZB 2EI6B 2VWOL 2WFXB 1GK5A 1NFYB 1YUGA 3IJEB 1ATEA 2W26B 1EGFA 4Y79B 1EAIC 2XBVL 2Y5GL 1F7MA 3LC3B 3MQEA 2WYGB 1CVUA 4XL1A 1APOA 4CUEA 2P95L 1EMOA 4O1ZA 2OYEP 4RUTA 4BTUA 3HO4A 4MMYB 4X8VL 2VH6B 1COUA 2Y5FL 4YT6L 1F7EA 1K37A 2BOHA 1EQGA 3QMOA 2I9BA 4NA9L 3ELAL 1J9CL 1EPGA 3IITB 2D1JB 2WPIE 1KSNB 2VWMK 5I46L 5JVZA 3S6XA 2UWLB 4X8TL 1MQ5L 1IQIL 2JKHL 1O5DL 4BTTA 3U7UG 3ASIA 5JBCE 4Y7AB 1SZBA 2W2NE 2W2ME 3GCWE 3LN0A 1ATAA 1G1SA 4D0EA 1IJQA 2RNLA 3NJPC 1HT5A 1CCFA 2W2OE 3F6UL 3N8WB 4ISIL 2WPKE 4YZUB 2Y38A 4D90A 1URKA 2BQ7A 2MGPA 2B7DL 4JZDL 3P5BL 3TBDA 1IOXA 1OB1C 2BQ6A 1L5GB 5E8DA 1BF9A 1XFEA 5JBBE 1NFUB 2NPRA 2W2QE 4FM5A 2H9EL 1LMJA 3BT2A 2UWOB 2M74A 2PR3B 1LQDA 3FFGL 5K0HB 1I0UA 1HRFA 1XDTR 3N8XA 2TGFA 3KK6A 2AYLA 5JVYA 1Z6EL 1WHEA 1TLEA 3N8ZA 3Q7DA 2VVVL 4ZXYL 3SW2A 5CISA 5F19A 1NZIA 1TPGA 2W3KB 3CA7A 4XLWA 1ATBA 2ADXA 2WPLE 1HJ7A 1ZAQA 3N8YA 3CFWA 2J2UB 2WFTA 2XC0L 1F0RB 1QFKL 2BZ6L 2FLGA 1NPEB 2YGOA 2MHPA 3ENSA 2P16L 3LTGD 3R05A 2KB9A 3POYA 4D0FA 3LIWB 4NGAL 1DIYA 1WU1B 3KRKA 4CUDA 2Y7XB 1KLJL 1FAXL 1Q4GA 2RA0L 5FDQA 2BOXA 2W2PE 4LORA 1G2LB 1FF7A 4XBMA 1UZPA 2FD6A 2WG4B 5IKVA 2FLRL 2Y80B 1HAEA 1UZKA 1AUTL 3GCXE 1NQLB 4Z6AL 3K9XA 1FJSL 5JW1A 3NTBA 2Q1JB 2KL7A 3HPTA 4OTJA 2XC4L 3OLTA 1U67A 2BOUA 1XKBA 3Q3KB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XC5 L;  1B9W A;  3N8W A;  2WPH E;  3GIS X;  3KL6 B;  1JV2 B;  2VVC K;  3TK5 B;  2G00 L;  2FLB L;  1PGE A;  1UZQ A;  3TZI A;  5IKR A;  1FSB A;  2Y5H L;  1IQF L;  4JYV L;  3V64 C;  1C5M F;  1G1T A;  2WPJ E;  3KQB L;  2J34 B;  5COX A;  4A7I A;  4O02 B;  4CUF A;  1UZJ A;  3ZYI B;  3C9A C;  1CCV A;  1IGX A;  2XBX L;  4BDW A;  5F1A A;  3SOB B;  2W86 A;  4Y76 B;  2F9B L;  3SOV A;  3NT1 A;  1P9J A;  3HS6 A;  1EMN A;  2BQW A;  3HO3 A;  3CEN L;  4X8U L;  1PTH A;  3TK6 B;  1NT0 A;  2P3T A;  1CX2 A;  3SOQ A;  1IQN L;  1XKA L;  2EI7 B;  5IKQ A;  4G1M B;  1U8C B;  1PRH A;  1YO8 A;  4Z0K B;  3KQD L;  2RHP A;  2J95 B;  3KQE L;  1DVA L;  4CSY A;  4ZHA B;  4AQT A;  2P3U A;  5JB8 E;  1YGC L;  1W7X L;  2VH0 B;  1LPZ A;  3PGH A;  1ATD A;  5L2Z L;  3MDL A;  1KLO A;  4E1G A;  4Z0L A;  1CQE A;  5KN5 C;  4COX A;  1IQH L;  2OYU P;  1W8B L;  4RRZ A;  3M36 L;  2PUQ L;  4BXW A;  4C16 A;  2J94 B;  5JB9 E;  4X8S L;  1APQ A;  2P93 L;  2MGR A;  2GD4 A;  3KCG L;  3U73 A;  2VWL L;  1F0S B;  3BT1 A;  2Y82 B;  1HT8 A;  2WG3 C;  1IQM L;  3HS7 A;  3OLU A;  3LTF B;  2BOK L;  1V3X B;  3TGF A;  3LN1 A;  1RFN B;  4ZXX L;  3KQC L;  2KV4 A;  3LC5 B;  1LPK A;  1DX5 I;  4YT7 L;  1ADX A;  1HX2 A;  1IQJ L;  1KIG L;  2P28 B;  4M11 A;  1JBU L;  4ISH L;  1IGZ A;  4BDX A;  3HO5 A;  5CKM A;  1EQH A;  1K36 A;  1NFX B;  1Z6C A;  3FBY A;  1TOZ A;  4JZE L;  5L2Y L;  4BXS A;  1YUK B;  2DDU A;  2P3F L;  4BTI A;  2XBW L;  4NG9 L;  1LPG A;  3BPS E;  1WHF A;  5L30 L;  2VJ3 A;  1FAK L;  1DDX A;  1MQ6 L;  1MOX C;  2VVU L;  1CEJ A;  2BO2 A;  1M1X B;  4Y6D B;  1IQE L;  1JL9 A;  2P26 A;  1A3P A;  4LMF A;  2P3F N;  4M10 A;  2BMG A;  5IKT A;  3RR3 A;  4OTY A;  3QCW A;  1FE2 A;  4ZH8 B;  3QH0 A;  5CKN A;  3FCS B;  3M37 L;  1YUF A;  1EPI A;  2UWP B;  1IQK L;  3EGF A;  1PXX A;  5EGM B;  3DEM A;  3N8V A;  3ZYJ B;  2YGP A;  1G1R A;  2WPM E;  4MMZ B;  1EZQ B;  1HAF A;  1KLI L;  2WYJ B;  2P94 L;  3LAQ A;  1EBV A;  4RRX A;  3NTG A;  6COX A;  1G1Q A;  4Y71 B;  1PFX L;  1G2M B;  2VWN L;  2W3I B;  5JBA E;  1HZ8 A;  1L3Y A;  1X7A L;  3F1S B;  2J38 B;  3HS5 A;  2FZZ L;  1IQL L;  1N1I A;  1IQG L;  2PHB B;  1HRE A;  1EPH A;  2CJI B;  4JZF L;  1EPJ A;  2XBY L;  4RRY A;  4ZAE B;  1HCG B;  3ZYG A;  3CS7 L;  1FFM A;  4JYU L;  4Y7B B;  1DQB A;  3TH3 L;  1P0S L;  2J4I B;  1N7D A;  5KIR A;  4RS0 A;  1CVW L;  1IP0 A;  1NFW B;  2EI8 B;  3V65 B;  2K2S B;  4RRW A;  2K2T A;  1IVO C;  3H5C B;  2Y81 B;  1IOE L;  3N8Y B;  4TGF A;  4MMX B;  5CKQ A;  4PH9 A;  2I9A A;  2Y7Z B;  2EI6 B;  2VWO L;  2WFX B;  1GK5 A;  1NFY B;  1YUG A;  3IJE B;  1ATE A;  2W26 B;  1EGF A;  4Y79 B;  1EAI C;  2XBV L;  2Y5G L;  1F7M A;  3LC3 B;  3MQE A;  2WYG B;  1CVU A;  4XL1 A;  1APO A;  4CUE A;  2P95 L;  1EMO A;  4O1Z A;  2OYE P;  4RUT A;  4BTU A;  3HO4 A;  4MMY B;  4X8V L;  2VH6 B;  1COU A;  2Y5F L;  4YT6 L;  1F7E A;  1K37 A;  2BOH A;  1EQG A;  3QMO A;  2I9B A;  4NA9 L;  3ELA L;  1J9C L;  1EPG A;  3IIT B;  2D1J B;  2WPI E;  1KSN B;  2VWM K;  5I46 L;  5JVZ A;  2UWL B;  4X8T L;  1MQ5 L;  1IQI L;  2JKH L;  1O5D L;  4BTT A;  3U7U G;  3ASI A;  5JBC E;  4Y7A B;  1SZB A;  2W2N E;  2W2M E;  3GCW E;  3LN0 A;  1ATA A;  1G1S A;  4D0E A;  1IJQ A;  2RNL A;  3NJP C;  1HT5 A;  1CCF A;  2W2O E;  3F6U L;  3N8W B;  4ISI L;  2WPK E;  4YZU B;  2Y38 A;  4D90 A;  1URK A;  2BQ7 A;  2MGP A;  2B7D L;  4JZD L;  3P5B L;  3TBD A;  1IOX A;  1OB1 C;  2BQ6 A;  1L5G B;  5E8D A;  1BF9 A;  1XFE A;  5JBB E;  1NFU B;  2NPR A;  2W2Q E;  4FM5 A;  2H9E L;  1LMJ A;  3BT2 A;  2UWO B;  2M74 A;  2PR3 B;  1LQD A;  3FFG L;  5K0H B;  1I0U A;  1HRF A;  1XDT R;  3N8X A;  2TGF A;  3KK6 A;  2AYL A;  5JVY A;  1Z6E L;  1WHE A;  1TLE A;  3N8Z A;  3Q7D A;  2VVV L;  4ZXY L;  3SW2 A;  5CIS A;  5F19 A;  1NZI A;  1TPG A;  2W3K B;  3CA7 A;  4XLW A;  1ATB A;  2ADX A;  2WPL E;  1HJ7 A;  1ZAQ A;  3N8Y A;  3CFW A;  2J2U B;  2WFT A;  2XC0 L;  1F0R B;  1QFK L;  2BZ6 L;  2FLG A;  1NPE B;  2YGO A;  2MHP A;  3ENS A;  2P16 L;  3LTG D;  3R05 A;  2KB9 A;  3POY A;  4D0F A;  3LIW B;  4NGA L;  1DIY A;  1WU1 B;  3KRK A;  4CUD A;  2Y7X B;  1KLJ L;  1FAX L;  1Q4G A;  2RA0 L;  5FDQ A;  2BOX A;  2W2P E;  4LOR A;  1G2L B;  1FF7 A;  4XBM A;  1UZP A;  2FD6 A;  2WG4 B;  5IKV A;  2FLR L;  2Y80 B;  1HAE A;  1UZK A;  1AUT L;  3GCX E;  1NQL B;  4Z6A L;  3K9X A;  1FJS L;  5JW1 A;  3NTB A;  2Q1J B;  2KL7 A;  3HPT A;  4OTJ A;  2XC4 L;  3OLT A;  1U67 A;  2BOU A;  1XKB A;  3Q3K B; 
#chains in the Genus database with same CATH topology
 2XC5 L;  1B9W A;  3N8W A;  2WPH E;  3GIS X;  3KL6 B;  1JV2 B;  2VVC K;  3TK5 B;  2G00 L;  2FLB L;  2HOR A;  1PGE A;  1UZQ A;  3TZI A;  5IKR A;  1FSB A;  2Y5H L;  1IQF L;  4JYV L;  3V64 C;  1C5M F;  1G1T A;  2WPJ E;  3KQB L;  2J34 B;  5COX A;  4A7I A;  4O02 B;  4CUF A;  1UZJ A;  3ZYI B;  3C9A C;  1CCV A;  1IGX A;  2XBX L;  4BDW A;  5F1A A;  3SOB B;  4GU3 A;  2W86 A;  4Y76 B;  2F9B L;  3SOV A;  3NT1 A;  1P9J A;  3HS6 A;  1EMN A;  2BQW A;  3HO3 A;  3CEN L;  4X8U L;  1PTH A;  3TK6 B;  1NT0 A;  2P3T A;  2BT7 A;  1CX2 A;  3SOQ A;  1IQN L;  1XKA L;  2EI7 B;  5IKQ A;  4G1M B;  1U8C B;  1PRH A;  2VRS A;  1YO8 A;  4Z0K B;  3KQD L;  2RHP A;  2J95 B;  3KQE L;  1DVA L;  4CSY A;  4ZHA B;  4AQT A;  2P3U A;  5JB8 E;  1YGC L;  1W7X L;  2VH0 B;  1LPZ A;  3PGH A;  1ATD A;  5L2Z L;  3MDL A;  4A94 C;  1KLO A;  4E1G A;  4Z0L A;  1LMM A;  1CQE A;  5KN5 C;  4COX A;  1IQH L;  2OYU P;  1W8B L;  4RRZ A;  3M36 L;  2PUQ L;  4BXW A;  4C16 A;  2J94 B;  5JB9 E;  4X8S L;  1APQ A;  2P93 L;  2MGR A;  2GD4 A;  3KCG L;  2WZP P;  2VWL L;  3U73 A;  1F0S B;  3BT1 A;  2Y82 B;  1HT8 A;  2WG3 C;  1IQM L;  3HS7 A;  3OLU A;  1QIU A;  3LTF B;  2BOK L;  1V3X B;  3TGF A;  3LN1 A;  1RFN B;  1V1I A;  3KQC L;  4ZXX L;  2KV4 A;  3LC5 B;  1LPK A;  1DX5 I;  4YT7 L;  1ADX A;  1HX2 A;  1IQJ L;  1KIG L;  2P28 B;  4M11 A;  1JBU L;  4ISH L;  2KNI A;  1IGZ A;  4BDX A;  3HO5 A;  5CKM A;  1EQH A;  1K36 A;  1NFX B;  1Z6C A;  2BT8 A;  3FBY A;  1TOZ A;  4JZE L;  5L2Y L;  4BXS A;  1YUK B;  2DDU A;  2P3F L;  4BTI A;  2XBW L;  4NG9 L;  1LPG A;  2YGQ A;  3BPS E;  1WHF A;  5L30 L;  2VJ3 A;  1FAK L;  1DDX A;  1MQ6 L;  1MOX C;  1LK9 A;  2VVU L;  1CEJ A;  2BO2 A;  1M1X B;  4Y6D B;  1IQE L;  1JL9 A;  2P26 A;  1A3P A;  4LMF A;  2P3F N;  4M10 A;  2BMG A;  5IKT A;  3RR3 A;  4OTY A;  3QCW A;  1FE2 A;  4ZH8 B;  3QH0 A;  5CKN A;  3FCS B;  3M37 L;  1YUF A;  1EPI A;  2UWP B;  1IQK L;  3EGF A;  1PXX A;  5EGM B;  3DEM A;  3N8V A;  3ZYJ B;  2YGP A;  1G1R A;  2WPM E;  4MMZ B;  1EZQ B;  1HAF A;  1KLI L;  2WYJ B;  2P94 L;  3LAQ A;  1EBV A;  2BSF A;  4RRX A;  3NTG A;  6COX A;  1G1Q A;  4Y71 B;  1PFX L;  1G2M B;  2VWN L;  2W3I B;  5JBA E;  1HZ8 A;  1L3Y A;  1X7A L;  3F1S B;  2J38 B;  3HS5 A;  2FZZ L;  1IQL L;  1N1I A;  1IQG L;  2PHB B;  1HRE A;  1EPH A;  2H9E C;  2CJI B;  4JZF L;  1EPJ A;  2XBY L;  4RRY A;  4ZAE B;  1HCG B;  3ZYG A;  3CS7 L;  1FFM A;  4JYU L;  4Y7B B;  1DQB A;  3TH3 L;  1P0S L;  2J4I B;  1N7D A;  5KIR A;  4RS0 A;  1CVW L;  1IP0 A;  1NFW B;  2EI8 B;  3V65 B;  2K2S B;  4RRW A;  2K2T A;  1IVO C;  3H5C B;  2Y81 B;  1IOE L;  3N8Y B;  4TGF A;  4MMX B;  5CKQ A;  4PH9 A;  2I9A A;  2Y7Z B;  2EI6 B;  2VWO L;  2WFX B;  1GK5 A;  1NFY B;  1YUG A;  3IJE B;  1ATE A;  2W26 B;  1EGF A;  4Y79 B;  1EAI C;  2XBV L;  2Y5G L;  1F7M A;  3LC3 B;  3MQE A;  2WYG B;  1CVU A;  4XL1 A;  1APO A;  4CUE A;  2P95 L;  1EMO A;  4O1Z A;  2OYE P;  4RUT A;  4BTU A;  3HO4 A;  4MMY B;  4X8V L;  2VH6 B;  1COU A;  2Y5F L;  4YT6 L;  1F7E A;  1K37 A;  2BOH A;  1EQG A;  3QMO A;  2I9B A;  4NA9 L;  3ELA L;  1J9C L;  1EPG A;  2HOX A;  3IIT B;  2D1J B;  2WPI E;  1KSN B;  2VWM K;  5I46 L;  5JVZ A;  3S6X A;  2UWL B;  4X8T L;  4GU4 A;  1MQ5 L;  1IQI L;  2JKH L;  1O5D L;  4BTT A;  3U7U G;  3ASI A;  5JBC E;  4Y7A B;  1SZB A;  2W2N E;  2W2M E;  3GCW E;  3LN0 A;  1ATA A;  1G1S A;  4D0E A;  1IJQ A;  2RNL A;  3NJP C;  1HT5 A;  1CCF A;  2W2O E;  3F6U L;  3N8W B;  4ISI L;  2WPK E;  4YZU B;  2Y38 A;  4D90 A;  1URK A;  2BQ7 A;  2MGP A;  2B7D L;  4JZD L;  3P5B L;  3TBD A;  1IOX A;  1OB1 C;  2BQ6 A;  1L5G B;  5E8D A;  1BF9 A;  1XFE A;  5JBB E;  1NFU B;  2NPR A;  2W2Q E;  4FM5 A;  2H9E L;  1LMJ A;  3BT2 A;  2UWO B;  2M74 A;  1KKE A;  2PR3 B;  1LQD A;  3FFG L;  5K0H B;  1I0U A;  1HRF A;  1XDT R;  3N8X A;  2TGF A;  3KK6 A;  2AYL A;  5JVY A;  1Z6E L;  1WHE A;  1TLE A;  3N8Z A;  3Q7D A;  2VVV L;  4ZXY L;  3SW2 A;  5CIS A;  5F19 A;  1NZI A;  1TPG A;  2W3K B;  3CA7 A;  4XLW A;  1ATB A;  2ADX A;  2JJL A;  2WPL E;  1HJ7 A;  1ZAQ A;  3N8Y A;  3CFW A;  2J2U B;  2WFT A;  2XC0 L;  1V1H A;  1F0R B;  1QFK L;  2BZ6 L;  2FLG A;  1NPE B;  2YGO A;  2MHP A;  3ENS A;  2P16 L;  3LTG D;  3R05 A;  2KB9 A;  3POY A;  4D0F A;  3LIW B;  4NGA L;  1DIY A;  1WU1 B;  3KRK A;  4CUD A;  2Y7X B;  1KLJ L;  1FAX L;  1Q4G A;  2RA0 L;  5FDQ A;  2BOX A;  2W2P E;  4LOR A;  1G2L B;  1FF7 A;  4XBM A;  1UZP A;  2FD6 A;  2WG4 B;  5IKV A;  2FLR L;  2Y80 B;  1HAE A;  1UZK A;  1AUT L;  3GCX E;  1NQL B;  4Z6A L;  3K9X A;  1FJS L;  5JW1 A;  3NTB A;  2Q1J B;  2KL7 A;  3HPT A;  4OTJ A;  2XC4 L;  3OLT A;  1U67 A;  2BOU A;  1XKB A;  3Q3K B; 
#chains in the Genus database with same CATH homology
 2XC5 L;  1B9W A;  3N8W A;  2WPH E;  3GIS X;  3KL6 B;  1JV2 B;  2VVC K;  3TK5 B;  2G00 L;  2FLB L;  1PGE A;  1UZQ A;  3TZI A;  5IKR A;  1FSB A;  2Y5H L;  1IQF L;  4JYV L;  3V64 C;  1C5M F;  1G1T A;  2WPJ E;  3KQB L;  2J34 B;  5COX A;  4A7I A;  4O02 B;  4CUF A;  1UZJ A;  3ZYI B;  3C9A C;  1CCV A;  1IGX A;  2XBX L;  4BDW A;  5F1A A;  3SOB B;  2W86 A;  4Y76 B;  2F9B L;  3SOV A;  3NT1 A;  1P9J A;  3HS6 A;  1EMN A;  2BQW A;  3HO3 A;  3CEN L;  4X8U L;  1PTH A;  3TK6 B;  1NT0 A;  2P3T A;  1CX2 A;  3SOQ A;  1IQN L;  1XKA L;  2EI7 B;  5IKQ A;  4G1M B;  1U8C B;  1PRH A;  1YO8 A;  4Z0K B;  3KQD L;  2RHP A;  2J95 B;  3KQE L;  1DVA L;  4CSY A;  4ZHA B;  4AQT A;  2P3U A;  5JB8 E;  1YGC L;  1W7X L;  2VH0 B;  1LPZ A;  3PGH A;  1ATD A;  5L2Z L;  3MDL A;  4A94 C;  1KLO A;  4E1G A;  4Z0L A;  1LMM A;  1CQE A;  5KN5 C;  4COX A;  1IQH L;  2OYU P;  1W8B L;  4RRZ A;  3M36 L;  2PUQ L;  4BXW A;  4C16 A;  2J94 B;  5JB9 E;  4X8S L;  1APQ A;  2P93 L;  2MGR A;  2GD4 A;  3KCG L;  2WZP P;  2VWL L;  3U73 A;  1F0S B;  3BT1 A;  2Y82 B;  1HT8 A;  2WG3 C;  1IQM L;  3HS7 A;  3OLU A;  3LTF B;  2BOK L;  1V3X B;  3TGF A;  3LN1 A;  1RFN B;  4ZXX L;  3KQC L;  2KV4 A;  3LC5 B;  1LPK A;  1DX5 I;  4YT7 L;  1ADX A;  1HX2 A;  1IQJ L;  1KIG L;  2P28 B;  4M11 A;  1JBU L;  4ISH L;  2KNI A;  1IGZ A;  4BDX A;  3HO5 A;  5CKM A;  1EQH A;  1K36 A;  1NFX B;  1Z6C A;  3FBY A;  1TOZ A;  4JZE L;  5L2Y L;  4BXS A;  1YUK B;  2DDU A;  2P3F L;  4BTI A;  2XBW L;  4NG9 L;  1LPG A;  2YGQ A;  3BPS E;  1WHF A;  5L30 L;  2VJ3 A;  1FAK L;  1DDX A;  1MQ6 L;  1MOX C;  2VVU L;  1CEJ A;  2BO2 A;  1M1X B;  4Y6D B;  1IQE L;  1JL9 A;  2P26 A;  1A3P A;  4LMF A;  2P3F N;  4M10 A;  2BMG A;  5IKT A;  3RR3 A;  4OTY A;  3QCW A;  1FE2 A;  4ZH8 B;  3QH0 A;  5CKN A;  3FCS B;  3M37 L;  1YUF A;  1EPI A;  2UWP B;  1IQK L;  3EGF A;  1PXX A;  5EGM B;  3DEM A;  3N8V A;  3ZYJ B;  2YGP A;  1G1R A;  2WPM E;  4MMZ B;  1EZQ B;  1HAF A;  1KLI L;  2WYJ B;  2P94 L;  3LAQ A;  1EBV A;  4RRX A;  3NTG A;  6COX A;  1G1Q A;  4Y71 B;  1PFX L;  1G2M B;  2VWN L;  2W3I B;  5JBA E;  1HZ8 A;  1L3Y A;  1X7A L;  3F1S B;  2J38 B;  3HS5 A;  2FZZ L;  1IQL L;  1N1I A;  1IQG L;  2PHB B;  1HRE A;  1EPH A;  2H9E C;  2CJI B;  4JZF L;  1EPJ A;  2XBY L;  4RRY A;  4ZAE B;  1HCG B;  3ZYG A;  3CS7 L;  1FFM A;  4JYU L;  4Y7B B;  1DQB A;  3TH3 L;  1P0S L;  2J4I B;  1N7D A;  5KIR A;  4RS0 A;  1CVW L;  1IP0 A;  1NFW B;  2EI8 B;  3V65 B;  2K2S B;  4RRW A;  2K2T A;  1IVO C;  3H5C B;  2Y81 B;  1IOE L;  3N8Y B;  4TGF A;  4MMX B;  5CKQ A;  4PH9 A;  2I9A A;  2Y7Z B;  2EI6 B;  2VWO L;  2WFX B;  1GK5 A;  1NFY B;  1YUG A;  3IJE B;  1ATE A;  2W26 B;  1EGF A;  4Y79 B;  1EAI C;  2XBV L;  2Y5G L;  1F7M A;  3LC3 B;  3MQE A;  2WYG B;  1CVU A;  4XL1 A;  1APO A;  4CUE A;  2P95 L;  1EMO A;  4O1Z A;  2OYE P;  4RUT A;  4BTU A;  3HO4 A;  4MMY B;  4X8V L;  2VH6 B;  1COU A;  2Y5F L;  4YT6 L;  1F7E A;  1K37 A;  2BOH A;  1EQG A;  3QMO A;  2I9B A;  4NA9 L;  3ELA L;  1J9C L;  1EPG A;  3IIT B;  2D1J B;  2WPI E;  1KSN B;  2VWM K;  5I46 L;  5JVZ A;  3S6X A;  2UWL B;  4X8T L;  1MQ5 L;  1IQI L;  2JKH L;  1O5D L;  4BTT A;  3U7U G;  3ASI A;  5JBC E;  4Y7A B;  1SZB A;  2W2N E;  2W2M E;  3GCW E;  3LN0 A;  1ATA A;  1G1S A;  4D0E A;  1IJQ A;  2RNL A;  3NJP C;  1HT5 A;  1CCF A;  2W2O E;  3F6U L;  3N8W B;  4ISI L;  2WPK E;  4YZU B;  2Y38 A;  4D90 A;  1URK A;  2BQ7 A;  2MGP A;  2B7D L;  4JZD L;  3P5B L;  3TBD A;  1IOX A;  1OB1 C;  2BQ6 A;  1L5G B;  5E8D A;  1BF9 A;  1XFE A;  5JBB E;  1NFU B;  2NPR A;  2W2Q E;  4FM5 A;  2H9E L;  1LMJ A;  3BT2 A;  2UWO B;  2M74 A;  2PR3 B;  1LQD A;  3FFG L;  5K0H B;  1I0U A;  1HRF A;  1XDT R;  3N8X A;  2TGF A;  3KK6 A;  2AYL A;  5JVY A;  1Z6E L;  1WHE A;  1TLE A;  3N8Z A;  3Q7D A;  2VVV L;  4ZXY L;  3SW2 A;  5CIS A;  5F19 A;  1NZI A;  1TPG A;  2W3K B;  3CA7 A;  4XLW A;  1ATB A;  2ADX A;  2WPL E;  1HJ7 A;  1ZAQ A;  3N8Y A;  3CFW A;  2J2U B;  2WFT A;  2XC0 L;  1F0R B;  1QFK L;  2BZ6 L;  2FLG A;  1NPE B;  2YGO A;  2MHP A;  3ENS A;  2P16 L;  3LTG D;  3R05 A;  2KB9 A;  3POY A;  4D0F A;  3LIW B;  4NGA L;  1DIY A;  1WU1 B;  3KRK A;  4CUD A;  2Y7X B;  1KLJ L;  1FAX L;  1Q4G A;  2RA0 L;  5FDQ A;  2BOX A;  2W2P E;  4LOR A;  1G2L B;  1FF7 A;  4XBM A;  1UZP A;  2FD6 A;  2WG4 B;  5IKV A;  2FLR L;  2Y80 B;  1HAE A;  1UZK A;  1AUT L;  3GCX E;  1NQL B;  4Z6A L;  3K9X A;  1FJS L;  5JW1 A;  3NTB A;  2Q1J B;  2KL7 A;  3HPT A;  4OTJ A;  2XC4 L;  3OLT A;  1U67 A;  2BOU A;  1XKB A;  3Q3K B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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