4ENG | Genus

Total Genus 67

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	67
sequence length	210
structure length	210
Chain Sequence	ADGRSTRYWNCCKPSCGWAKKAPVNQPVFSCNANFQRITDFDAKSGCEPGGVAYSCADQTPWAVNDDFALGFAATSIAGSNEAGWCCACYELTFTSGPVAGKKMVVQSTSTGGDLGSNHFDLNIPGGGVGIFDGCTPQFGGLPGQRYGGISSRNECDRFPDALKPGCYWRFDWFKNADNPSFSFRQVQCPAELVARTGCRRNDDGNFPAV

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Glycosyl hydrolase
source organism	Humicola insolens
publication title	Structure determination and refinement of the Humicola insolens endoglucanase V at 1.5 A resolution. pubmed doi rcsb
molecule keywords	ENDOGLUCANASE V CELLOHEXAOSE COMPLEX
total genus	67
structure length	210
sequence length	210
ec nomenclature	ec 3.2.1.4: Cellulase.
pdb deposition date	1996-10-17

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02015	Glyco_hydro_45	Glycosyl hydrolase family 45

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.40.40.10	Mainly Beta	Beta Barrel	Barwin-like endoglucanases	RlpA-like domain	4engA00

2PNWA 4JS7A 1OA9A 2HCZX 2GAEA 4FG4A 2G5DA 1WC2A 3X2GA 3X2HA 3D30A 4FFTA 3X2NA 1N10A 2G6GA 3X2IA 2AE0X 5GLYA 3X2KA 5GM9A 2PICA 3CZBA 4JCWA 4AVRA 1BW3A 2ENGA 3SUMA 4FERA 3X2LA 3X2JA 5GLXA 1HD5A 1L8FA 3ENGA 3M3GA 2BH0A 3X2PA 2KQAA 3SUKA 4ZM7A 1OA7A 3SULA 4ENGA 2PJJA 4FG2A 5H4UA 4L48A 3SUJA 4JP6A 1BW4A 4JP7A 2PI8A 3X2OA 4JJOA 3X2MA
chains in the Genus database with same CATH superfamily

2JIMA 4NOHA 5GLFA 4D7ZB 1YNND 1OA9A 2GAEA 1I50A 1QDNA 2PMZA 3GTMA 3D30A 2E2HA 4KO8A 1N10A 2V3VA 2VPZA 2O5JD 2ENGA 3HU2A 3X2JA 1G8JA 2JA6A 4KDLA 1E61A 2WB1A 4RV0A 1WLFA 5FTKA 1E18A 3IR5A 1R27A 1ZC1A 1KQFA 5FTMA 1YLEA 2VUMA 4FG2A 1FDIA 1PYUB 1DMRA 3QQ8A 1CR5A 2NYAA 3GTLA 3O5AA 3TIWA 3X2OA 4AOKB 1PPYA 3GTKA 2VPYA 4GA5A 1WC2A 1E32A 3X2GA 2R92A 2WAQA 2A6ED 2E2IA 4C2MA 1R9TA 1R7RA 2E7ZA 2CW0D 5T5MD 1UHEA 2AE0X 2C45A 3QC8A 2PJHB 5GM9A 3GTPA 1TWAA 3SUMA 3X2LA 1H5NA 5DYIA 2A69D 1Y1WA 3GTGA 1HD5A 1E5VA 1TMOA 5DYGA 2JIRA 2A6HD 1AW8B 2BH0A 5B6CA 3HKZA 5C1BA 3PLXB 1TWCA 5FTLA 2YU9A 4KDIA 1OGYA 2JIQA 2NAPA 2JA5A 3SUJA 2BE5D 1Y1VA 1TWHA 2PI8A 3M3GA 4JJOA 1CZ4A 4GA6A 1TWFA 2JIOA 4QIWA 3GTOA 1PT1A 1CZ5A 2JA7A 1SIWA 2B63A 2YUJA 3FKIA 1ZYRD 4FFTA 2R93A 2KI8A 3X2NA 4CS0A 2G6GA 3X2IA 5GLYA 3X2KA 4AVRA 2PICA 1YNJD 1G8KA 1K83A 4AYBA 4CRZA 1EU1A 2VPWA 4KLNA 3DMRA 4DMRA 3QQ7A 3ENGA 1Y4ZA 1SFOA 1Y5IA 3SUKA 5EPPA 2Y0SA 3TM7B 1TWGA 3SULA 2V45A 5H4UA 4L48A 5C18A 1BW4A 1DMSA 1WCMA 1AA6A 1SMYD 1KQGA 3GTQA 3X2MA 2DMRA 1QCSA 1UHDA 2PNWA 2JIPA 4JS7A 2HCZX 5T5ID 4CRYG 4FG4A 1IW7D 1PT0A 1PQEA 2G5DA 2A68D 3OUGA 1PQFA 3X2HA 1Q16A 2R7ZA 1S3SA 3H0GA 3CZBA 4JCWA 5FTJA 2VPXA 3QWZA 4AONB 1BW3A 4FERA 1FDOA 1H0HA 1E60A 5GLXA 3GTJA 2NVYA 1L8FA 3CQZA 3X2PA 3IR7A 1I3QA 2KQAA 1PQHA 4ZM7A 3HU1A 3IR6A 1OA7A 4AAYA 4ENGA 3CF2A 3ML1A 2PJJA 5FTNA 1VC3B 4KODA 4JP6A 4JP7A 1PYQA 2EEOB 4AZDA 2NVXA 3HU3A 2IV2X
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2PNW A;  4JS7 A;  1OA9 A;  2HCZ X;  2GAE A;  4FG4 A;  2G5D A;  1WC2 A;  3X2G A;  3X2H A;  3D30 A;  4FFT A;  3X2N A;  1N10 A;  2G6G A;  3X2I A;  2AE0 X;  5GLY A;  3X2K A;  5GM9 A;  2PIC A;  3CZB A;  4JCW A;  4AVR A;  1BW3 A;  2ENG A;  3SUM A;  4FER A;  3X2L A;  3X2J A;  5GLX A;  1HD5 A;  1L8F A;  3ENG A;  3M3G A;  2BH0 A;  3X2P A;  2KQA A;  3SUK A;  4ZM7 A;  1OA7 A;  3SUL A;  4ENG A;  2PJJ A;  4FG2 A;  5H4U A;  4L48 A;  3SUJ A;  4JP6 A;  1BW4 A;  4JP7 A;  2PI8 A;  3X2O A;  4JJO A;  3X2M A; 
#chains in the Genus database with same CATH topology
 2JIM A;  4NOH A;  5GLF A;  4D7Z B;  1YNN D;  1OA9 A;  2GAE A;  1I50 A;  1QDN A;  2PMZ A;  3GTM A;  3D30 A;  2E2H A;  4KO8 A;  1N10 A;  2V3V A;  2VPZ A;  2O5J D;  2ENG A;  3HU2 A;  3X2J A;  1G8J A;  2JA6 A;  4KDL A;  1E61 A;  2WB1 A;  4RV0 A;  1WLF A;  5FTK A;  1E18 A;  3IR5 A;  1R27 A;  1ZC1 A;  1KQF A;  5FTM A;  1YLE A;  2VUM A;  4FG2 A;  1FDI A;  1PYU B;  1DMR A;  3QQ8 A;  1CR5 A;  2NYA A;  3GTL A;  3O5A A;  3TIW A;  3X2O A;  4AOK B;  1PPY A;  3GTK A;  2VPY A;  4GA5 A;  1WC2 A;  1E32 A;  3X2G A;  2R92 A;  2WAQ A;  2A6E D;  2E2I A;  4C2M A;  1R9T A;  1R7R A;  2E7Z A;  2CW0 D;  5T5M D;  1UHE A;  2AE0 X;  2C45 A;  3QC8 A;  2PJH B;  5GM9 A;  3GTP A;  1TWA A;  3SUM A;  3X2L A;  1H5N A;  5DYI A;  2A69 D;  1Y1W A;  3GTG A;  1HD5 A;  1E5V A;  1TMO A;  5DYG A;  2JIR A;  2A6H D;  1AW8 B;  2BH0 A;  5B6C A;  3HKZ A;  5C1B A;  3PLX B;  1TWC A;  5FTL A;  2YU9 A;  4KDI A;  1OGY A;  2JIQ A;  2NAP A;  2JA5 A;  3SUJ A;  2BE5 D;  1Y1V A;  1TWH A;  2PI8 A;  3M3G A;  4JJO A;  1CZ4 A;  4GA6 A;  1TWF A;  2JIO A;  4QIW A;  3GTO A;  1PT1 A;  1CZ5 A;  2JA7 A;  1SIW A;  2B63 A;  2YUJ A;  3FKI A;  1ZYR D;  4FFT A;  2R93 A;  2KI8 A;  3X2N A;  4CS0 A;  2G6G A;  3X2I A;  5GLY A;  3X2K A;  4AVR A;  2PIC A;  1YNJ D;  1G8K A;  1K83 A;  4AYB A;  4CRZ A;  1EU1 A;  2VPW A;  4KLN A;  3DMR A;  4DMR A;  3QQ7 A;  3ENG A;  1Y4Z A;  1SFO A;  1Y5I A;  3SUK A;  5EPP A;  2Y0S A;  3TM7 B;  1TWG A;  3SUL A;  2V45 A;  5H4U A;  4L48 A;  5C18 A;  1BW4 A;  1DMS A;  1WCM A;  1AA6 A;  1SMY D;  1KQG A;  3GTQ A;  3X2M A;  2DMR A;  1QCS A;  1UHD A;  2PNW A;  2JIP A;  4JS7 A;  2HCZ X;  5T5I D;  4CRY G;  4FG4 A;  1IW7 D;  1PT0 A;  1PQE A;  2G5D A;  2A68 D;  3OUG A;  1PQF A;  3X2H A;  1Q16 A;  2R7Z A;  1S3S A;  3H0G A;  3CZB A;  4JCW A;  5FTJ A;  2VPX A;  3QWZ A;  4AON B;  1BW3 A;  4FER A;  1FDO A;  1H0H A;  1E60 A;  5GLX A;  3GTJ A;  2NVY A;  1L8F A;  3CQZ A;  3X2P A;  3IR7 A;  1I3Q A;  2KQA A;  1PQH A;  4ZM7 A;  3HU1 A;  3IR6 A;  1OA7 A;  4AAY A;  4ENG A;  3CF2 A;  3ML1 A;  2PJJ A;  5FTN A;  1VC3 B;  4KOD A;  4JP6 A;  4JP7 A;  1PYQ A;  2EEO B;  4AZD A;  2NVX A;  3HU3 A;  2IV2 X; 
#chains in the Genus database with same CATH homology
 2PNW A;  4JS7 A;  1OA9 A;  2HCZ X;  2GAE A;  4FG4 A;  2G5D A;  1WC2 A;  3X2G A;  3X2H A;  3D30 A;  4FFT A;  3X2N A;  1N10 A;  2G6G A;  3X2I A;  2AE0 X;  5GLY A;  3X2K A;  5GM9 A;  2PIC A;  3CZB A;  4JCW A;  4AVR A;  1BW3 A;  2ENG A;  3SUM A;  4FER A;  3X2L A;  3X2J A;  5GLX A;  1HD5 A;  1L8F A;  3ENG A;  3M3G A;  2BH0 A;  3X2P A;  2KQA A;  3SUK A;  4ZM7 A;  1OA7 A;  3SUL A;  4ENG A;  2PJJ A;  4FG2 A;  5H4U A;  4L48 A;  3SUJ A;  4JP6 A;  1BW4 A;  4JP7 A;  2PI8 A;  3X2O A;  4JJO A;  3X2M A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4ENGA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations