4ISIL

Structure of factor viia in complex with the inhibitor (6s)-n-(4-carbamimidoylbenzyl)-1-chloro-3-(cyclobutylamino)-8,8-diethyl-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrazine-6-carboxamide
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
55
structure length
55
Chain Sequence
ICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design and synthesis of bicyclic pyrazinone and pyrimidinone amides as potent TF-FVIIa inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Factor VII heavy chain
total genus 12
structure length 55
sequence length 55
ec nomenclature ec 3.4.21.21: Coagulation factor VIIa.
pdb deposition date 2013-01-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 4isiL00
4Y79B 1JV2B 3KQBL 4YT6L 3ASIA 1HJ7A 2K2SB 2P26A 3KQCL 4ZHAB 3CS7L 1M1XB 1EAIC 2B7DL 4X8UL 4JYUL 4NA9L 3IJEB 1EPHA 1XFEA 1DIYA 4AQTA 1NZIA 5KIRA 1QFKL 1LPGA 1G1TA 2TGFA 1IQEL 4CUEA 4C16A 3IITB 2MGRA 4M11A 4X8VL 1HX2A 2EI8B 2XC0L 3FBYA 2KL7A 3N8ZA 3FCSB 1GK5A 2WG3C 1W8BL 2BOKL 4TGFA 2VVVL 2P3FN 3LTFB 1L3YA 4Y7AB 4COXA 2RA0L 3Q7DA 5E8DA 3ELAL 3CA7A 3CFWA 2XC5L 4BXSA 2WPME 1WU1B 1ATDA 1EZQB 3N8YB 1FSBA 2VH6B 1TPGA 1ATBA 1NQLB 1IQKL 1C5MF 2I9BA 2W2OE 3HS6A 4CUFA 1SZBA 1EBVA 5K0HB 4D90A 2P3FL 1WHFA 1EQGA 3TZIA 2VWNL 1AUTL 4BTUA 3GCXE 3DEMA 3FFGL 1IJQA 3TK6B 5IKVA 4XLWA 1IQNL 2PHBB 2P94L 1COUA 5F19A 2Y80B 2FLRL 2EI7B 2BQ7A 1N1IA 1G2LB 1FF7A 3V65B 1CCFA 5L30L 1MQ5L 4X8TL 1HT8A 3QMOA 4LMFA 4ZH8B 3HS5A 1YUGA 3ENSA 3N8VA 1EMNA 3OLTA 4Y71B 2J34B 2VH0B 2P3TA 3SW2A 1Z6CA 3M37L 1IQGL 5JBCE 4OTJA 3KL6B 4X8SL 4FM5A 2MHPA 3HO4A 1MOXC 2VVCK 3H5CB 2Y82B 2AYLA 5IKRA 2FLBL 5L2ZL 1FFMA 4JYVL 2KB9A 2FLGA 2K2TA 4BDXA 1V3XB 2RNLA 2G00L 1UZKA 1UZQA 3HO3A 1IQLL 1URKA 2WFXB 6COXA 2BO2A 3R05A 1G1SA 4NG9L 4ZXYL 1APOA 1X7AL 3F6UL 4NGAL 5JBBE 2W86A 2J94B 3KRKA 3MQEA 4Y7BB 1KLIL 3NTBA 3SOQA 1NFYB 1CVUA 2NPRA 4BTIA 4O1ZA 4XBMA 3TGFA 1Z6EL 2BOXA 2Y38A 2D1JB 2F9BL 4ISHL 3ZYGA 1IGXA 5JB8E 1I0UA 1HT5A 2MGPA 1IOEL 4RRWA 2P95L 1JBUL 2BZ6L 1ATAA 2RHPA 1HREA 4BXWA 1APQA 1IOXA 3M36L 3PGHA 4Z0KB 1W7XL 1HZ8A 2Y7XB 2ADXA 3HPTA 3HS7A 1XKAL 1PTHA 2W2NE 2M74A 5JVYA 1LQDA 3SOBB 2WPKE 1KLJL 2J38B 1NFXB 1UZPA 3Q3KB 4BDWA 1G1RA 1KSNB 2WPHE 4OTYA 1P9JA 1IGZA 2XBWL 5JVZA 2WYJB 2W26B 1FAKL 2Y5FL 2P3UA 5COXA 1F0RB 5CKQA 3MDLA 5JB9E 2UWOB 2DDUA 2Y81B 4JZDL 3RR3A 1TLEA 4JZFL 1YUKB 4D0EA 3QCWA 1EQHA 3BT2A 1HAFA 2H9EL 1IQHL 4RRZA 2P93L 2YGPA 3V64C 3OLUA 4JZEL 3NT1A 5FDQA 1OB1C 3NTGA 3TH3L 1B9WA 3F1SB 1KLOA 3LTGD 4ZXXL 2XBVL 2BOHA 3EGFA 1IQML 2P16L 1ATEA 1HAEA 2YGOA 1PXXA 1LMJA 1YO8A 3GCWE 2Q1JB 3LN1A 2VVUL 3U7UG 1KIGL 4Z0LA 2J2UB 1FE2A 4O02B 2XBXL 1A3PA 4ZAEB 2CJIB 5F1AA 3LAQA 3LC5B 1K36A 3SOVA 2OYUP 3KK6A 4MMYB 1P0SL 1U8CB 1MQ6L 2W2QE 3TBDA 2Y5GL 5JW1A 2WFTA 2JKHL 4LORA 1XDTR 1ADXA 4RRXA 4A7IA 3CENL 1CVWL 1CCVA 3K9XA 3KQDL 4E1GA 2GD4A 1DDXA 1UZJA 1IVOC 2VJ3A 1LPZA 4ISIL 3BPSE 4RUTA 5CKMA 1G2MB 2Y7ZB 2W2ME 2UWPB 4D0FA 4CUDA 4M10A 1F7EA 2PUQL 4PH9A 1CQEA 1ZAQA 4Y76B 1U67A 3N8XA 1RFNB 1F7MA 2W2PE 2BOUA 2VWOL 4MMXB 1N7DA 1XKBA 1K37A 1EMOA 2J4IB 5CISA 1HCGB 1NFUB 3HO5A 2WG4B 2I9AA 4XL1A 4CSYA 1Q4GA 2UWLB 3QH0A 5JBAE 4BTTA 1IQFL 1NFWB 3LN0A 3KCGL 2WYGB 1CEJA 3LC3B 3N8YA 2WPIE 1IP0A 4YT7L 2PR3B 5KN5C 2FD6A 4Z6AL 5IKTA 1EPGA 4MMZB 3GISX 1YUFA 2P28B 5EGMB 2VWMK 1L5GB 3NJPC 1HRFA 2XC4L 3N8WB 2KV4A 1IQJL 1IQIL 2BMGA 5IKQA 2WPJE 3N8WA 3TK5B 3KQEL 3C9AC 3ZYIB 1YGCL 1DX5I 3POYA 1NPEB 1PFXL 5L2YL 2Y5HL 3U73A 3P5BL 2FZZL 1PRHA 1FJSL 2BQ6A 2J95B 2VWLL 1DQBA 1DVAL 1TOZA 2OYEP 5CKNA 1EPJA 1WHEA 3LIWB 3ZYJB 1CX2A 1G1QA 2W3KB 1PGEA 1LPKA 1NT0A 4RS0A 3BT1A 2W3IB 4Y6DB 1F0SB 4YZUB 1EGFA 1O5DL 1EPIA 1FAXL 2BQWA 2EI6B 1JL9A 1J9CL 5I46L 4RRYA 4G1MB 2WPLE 2XBYL 1BF9A
chains in the Genus database with same CATH superfamily
4Y79B 1JV2B 3KQBL 4YT6L 3ASIA 1HJ7A 2K2SB 2P26A 3KQCL 1V1IA 4ZHAB 3CS7L 1M1XB 1EAIC 2B7DL 4X8UL 4JYUL 4NA9L 3IJEB 1EPHA 1XFEA 1DIYA 4AQTA 1NZIA 5KIRA 1QFKL 1LMMA 1LPGA 1G1TA 2TGFA 1IQEL 4CUEA 4C16A 3IITB 2MGRA 4M11A 2BSFA 2JJLA 4X8VL 1HX2A 2EI8B 2XC0L 2YGQA 3FBYA 2KL7A 3N8ZA 3FCSB 1GK5A 2WG3C 1W8BL 2BOKL 4TGFA 2VVVL 2P3FN 3LTFB 1L3YA 4Y7AB 4COXA 2RA0L 3Q7DA 5E8DA 3ELAL 3CA7A 3CFWA 2XC5L 4BXSA 2WPME 1WU1B 1ATDA 1EZQB 3N8YB 1KKEA 2VH6B 1TPGA 1FSBA 1ATBA 1NQLB 2H9EC 1IQKL 1C5MF 2I9BA 2W2OE 3HS6A 4CUFA 1SZBA 1EBVA 3S6XA 5K0HB 4D90A 2P3FL 1WHFA 4A94C 1EQGA 3TZIA 2VWNL 1AUTL 4BTUA 3GCXE 3DEMA 3FFGL 1IJQA 3TK6B 5IKVA 4XLWA 1IQNL 2WZPP 2PHBB 2P94L 1COUA 5F19A 2Y80B 2FLRL 2EI7B 2BQ7A 1N1IA 1G2LB 1FF7A 3V65B 1CCFA 5L30L 1MQ5L 4X8TL 1HT8A 3QMOA 4LMFA 4ZH8B 3HS5A 1YUGA 3ENSA 3N8VA 1EMNA 3OLTA 4Y71B 2J34B 2VH0B 2P3TA 3SW2A 1Z6CA 3M37L 1IQGL 5JBCE 4OTJA 3KL6B 4X8SL 4FM5A 2MHPA 3HO4A 1MOXC 2VVCK 3H5CB 2Y82B 2AYLA 5IKRA 2FLBL 5L2ZL 1FFMA 2KNIA 4JYVL 2KB9A 2FLGA 2K2TA 4BDXA 1V3XB 2HOXA 2RNLA 2G00L 1UZKA 1UZQA 3HO3A 1IQLL 1URKA 4GU3A 2WFXB 6COXA 2BO2A 3R05A 4GU4A 1G1SA 4NG9L 4ZXYL 1APOA 1X7AL 3F6UL 4NGAL 5JBBE 2W86A 2J94B 3KRKA 3MQEA 4Y7BB 1KLIL 3NTBA 3SOQA 1NFYB 1CVUA 2NPRA 4BTIA 4O1ZA 4XBMA 3TGFA 1Z6EL 2BOXA 2Y38A 2D1JB 2F9BL 4ISHL 3ZYGA 1IGXA 5JB8E 1I0UA 1HT5A 2MGPA 1IOEL 4RRWA 2P95L 1JBUL 2BZ6L 1ATAA 2RHPA 1HREA 4BXWA 1APQA 1IOXA 3M36L 3PGHA 4Z0KB 1W7XL 1HZ8A 2Y7XB 2ADXA 3HPTA 3HS7A 1XKAL 1PTHA 2W2NE 2M74A 5JVYA 2HORA 1LQDA 3SOBB 2WPKE 1KLJL 2J38B 1NFXB 1UZPA 3Q3KB 4BDWA 1G1RA 1KSNB 2WPHE 4OTYA 1P9JA 1IGZA 2XBWL 5JVZA 2WYJB 2W26B 1FAKL 2Y5FL 2P3UA 5COXA 1F0RB 5CKQA 3MDLA 5JB9E 2UWOB 2DDUA 2Y81B 4JZDL 3RR3A 1TLEA 4JZFL 1YUKB 4D0EA 3QCWA 1EQHA 3BT2A 1HAFA 2H9EL 1IQHL 4RRZA 2P93L 2YGPA 3V64C 3OLUA 4JZEL 3NT1A 5FDQA 1OB1C 3NTGA 3TH3L 1B9WA 3F1SB 1KLOA 3LTGD 4ZXXL 2XBVL 1QIUA 2BOHA 3EGFA 1IQML 2P16L 1ATEA 1HAEA 2YGOA 1PXXA 1LMJA 1YO8A 3GCWE 2Q1JB 3LN1A 2VVUL 3U7UG 1KIGL 4Z0LA 2J2UB 1FE2A 4O02B 2XBXL 1A3PA 1V1HA 4ZAEB 2CJIB 5F1AA 3LAQA 3LC5B 1K36A 3SOVA 2OYUP 3KK6A 4MMYB 1P0SL 1U8CB 1MQ6L 2W2QE 3TBDA 2Y5GL 5JW1A 2WFTA 2JKHL 4LORA 1XDTR 1ADXA 4RRXA 4A7IA 3CENL 1CVWL 1CCVA 3K9XA 3KQDL 4E1GA 2GD4A 1DDXA 1UZJA 1IVOC 2VJ3A 1LPZA 4ISIL 3BPSE 4RUTA 5CKMA 1G2MB 2Y7ZB 2W2ME 2UWPB 4D0FA 4CUDA 4M10A 1F7EA 2PUQL 4PH9A 1CQEA 1ZAQA 4Y76B 1U67A 3N8XA 1RFNB 1F7MA 2W2PE 2BOUA 2VWOL 4MMXB 1N7DA 1XKBA 1K37A 1EMOA 2J4IB 5CISA 1LK9A 1HCGB 1NFUB 3HO5A 2WG4B 2I9AA 4XL1A 4CSYA 1Q4GA 2UWLB 3QH0A 2BT7A 5JBAE 4BTTA 1IQFL 1NFWB 3LN0A 3KCGL 2WYGB 1CEJA 3LC3B 3N8YA 2WPIE 1IP0A 4YT7L 2PR3B 5KN5C 2FD6A 4Z6AL 5IKTA 1EPGA 4MMZB 3GISX 1YUFA 2P28B 5EGMB 2VWMK 1L5GB 3NJPC 1HRFA 2XC4L 3N8WB 2KV4A 1IQJL 1IQIL 2BMGA 5IKQA 2WPJE 3N8WA 3TK5B 3KQEL 3C9AC 3ZYIB 1YGCL 1DX5I 3POYA 1NPEB 1PFXL 5L2YL 2Y5HL 3U73A 3P5BL 2FZZL 1PRHA 1FJSL 2BT8A 2VRSA 2BQ6A 2J95B 2VWLL 1DQBA 1DVAL 1TOZA 2OYEP 5CKNA 1EPJA 1WHEA 3LIWB 3ZYJB 1CX2A 1G1QA 2W3KB 1PGEA 1LPKA 1NT0A 4RS0A 3BT1A 2W3IB 4Y6DB 1F0SB 4YZUB 1EGFA 1O5DL 1EPIA 1FAXL 2BQWA 2EI6B 1JL9A 1J9CL 5I46L 4RRYA 4G1MB 2WPLE 2XBYL 1BF9A
chains in the Genus database with same CATH topology
4Y79B 1JV2B 3KQBL 4YT6L 3ASIA 1HJ7A 2K2SB 2P26A 3KQCL 4ZHAB 3CS7L 1M1XB 1EAIC 2B7DL 4X8UL 4JYUL 4NA9L 3IJEB 1EPHA 1XFEA 1DIYA 4AQTA 1NZIA 5KIRA 1QFKL 1LMMA 1LPGA 1G1TA 2TGFA 1IQEL 4CUEA 4C16A 3IITB 2MGRA 4M11A 4X8VL 1HX2A 2EI8B 2XC0L 2YGQA 3FBYA 2KL7A 3N8ZA 3FCSB 1GK5A 2WG3C 1W8BL 2BOKL 4TGFA 2VVVL 2P3FN 3LTFB 1L3YA 4Y7AB 4COXA 2RA0L 3Q7DA 5E8DA 3ELAL 3CA7A 3CFWA 2XC5L 4BXSA 2WPME 1WU1B 1ATDA 1EZQB 3N8YB 1FSBA 2VH6B 1TPGA 1ATBA 1NQLB 2H9EC 1IQKL 1C5MF 2I9BA 2W2OE 3HS6A 4CUFA 1SZBA 1EBVA 3S6XA 5K0HB 4D90A 2P3FL 1WHFA 4A94C 1EQGA 3TZIA 2VWNL 1AUTL 4BTUA 3GCXE 3DEMA 3FFGL 1IJQA 3TK6B 5IKVA 4XLWA 1IQNL 2WZPP 2PHBB 2P94L 1COUA 5F19A 2Y80B 2FLRL 2EI7B 2BQ7A 1N1IA 1G2LB 1FF7A 3V65B 1CCFA 5L30L 1MQ5L 4X8TL 1HT8A 3QMOA 4LMFA 4ZH8B 3HS5A 1YUGA 3ENSA 3N8VA 1EMNA 3OLTA 4Y71B 2J34B 2VH0B 2P3TA 3SW2A 1Z6CA 3M37L 1IQGL 5JBCE 4OTJA 3KL6B 4X8SL 4FM5A 2MHPA 3HO4A 1MOXC 2VVCK 3H5CB 2Y82B 2AYLA 5IKRA 2FLBL 5L2ZL 1FFMA 2KNIA 4JYVL 2KB9A 2FLGA 2K2TA 4BDXA 1V3XB 2RNLA 2G00L 1UZKA 1UZQA 3HO3A 1IQLL 1URKA 2WFXB 6COXA 2BO2A 3R05A 1G1SA 4NG9L 4ZXYL 1APOA 1X7AL 3F6UL 4NGAL 5JBBE 2W86A 2J94B 3KRKA 3MQEA 4Y7BB 1KLIL 3NTBA 3SOQA 1NFYB 1CVUA 2NPRA 4BTIA 4O1ZA 4XBMA 3TGFA 1Z6EL 2BOXA 2Y38A 2D1JB 2F9BL 4ISHL 3ZYGA 1IGXA 5JB8E 1I0UA 1HT5A 2MGPA 1IOEL 4RRWA 2P95L 1JBUL 2BZ6L 1ATAA 2RHPA 1HREA 4BXWA 1APQA 1IOXA 3M36L 3PGHA 4Z0KB 1W7XL 1HZ8A 2Y7XB 2ADXA 3HPTA 3HS7A 1XKAL 1PTHA 2W2NE 2M74A 5JVYA 1LQDA 3SOBB 2WPKE 1KLJL 2J38B 1NFXB 1UZPA 3Q3KB 4BDWA 1G1RA 1KSNB 2WPHE 4OTYA 1P9JA 1IGZA 2XBWL 5JVZA 2WYJB 2W26B 1FAKL 2Y5FL 2P3UA 5COXA 1F0RB 5CKQA 3MDLA 5JB9E 2UWOB 2DDUA 2Y81B 4JZDL 3RR3A 1TLEA 4JZFL 1YUKB 4D0EA 3QCWA 1EQHA 3BT2A 1HAFA 2H9EL 1IQHL 4RRZA 2P93L 2YGPA 3V64C 3OLUA 4JZEL 3NT1A 5FDQA 1OB1C 3NTGA 3TH3L 1B9WA 3F1SB 1KLOA 3LTGD 4ZXXL 2XBVL 2BOHA 3EGFA 1IQML 2P16L 1ATEA 1HAEA 2YGOA 1PXXA 1LMJA 1YO8A 3GCWE 2Q1JB 3LN1A 2VVUL 3U7UG 1KIGL 4Z0LA 2J2UB 1FE2A 4O02B 2XBXL 1A3PA 4ZAEB 2CJIB 5F1AA 3LAQA 3LC5B 1K36A 3SOVA 2OYUP 3KK6A 4MMYB 1P0SL 1U8CB 1MQ6L 2W2QE 3TBDA 2Y5GL 5JW1A 2WFTA 2JKHL 4LORA 1XDTR 1ADXA 4RRXA 4A7IA 3CENL 1CVWL 1CCVA 3K9XA 3KQDL 4E1GA 2GD4A 1DDXA 1UZJA 1IVOC 2VJ3A 1LPZA 4ISIL 3BPSE 4RUTA 5CKMA 1G2MB 2Y7ZB 2W2ME 2UWPB 4D0FA 4CUDA 4M10A 1F7EA 2PUQL 4PH9A 1CQEA 1ZAQA 4Y76B 1U67A 3N8XA 1RFNB 1F7MA 2W2PE 2BOUA 2VWOL 4MMXB 1N7DA 1XKBA 1K37A 1EMOA 2J4IB 5CISA 1HCGB 1NFUB 3HO5A 2WG4B 2I9AA 4XL1A 4CSYA 1Q4GA 2UWLB 3QH0A 5JBAE 4BTTA 1IQFL 1NFWB 3LN0A 3KCGL 2WYGB 1CEJA 3LC3B 3N8YA 2WPIE 1IP0A 4YT7L 2PR3B 5KN5C 2FD6A 4Z6AL 5IKTA 1EPGA 4MMZB 3GISX 1YUFA 2P28B 5EGMB 2VWMK 1L5GB 3NJPC 1HRFA 2XC4L 3N8WB 2KV4A 1IQJL 1IQIL 2BMGA 5IKQA 2WPJE 3N8WA 3TK5B 3KQEL 3C9AC 3ZYIB 1YGCL 1DX5I 3POYA 1NPEB 1PFXL 5L2YL 2Y5HL 3U73A 3P5BL 2FZZL 1PRHA 1FJSL 2BQ6A 2J95B 2VWLL 1DQBA 1DVAL 1TOZA 2OYEP 5CKNA 1EPJA 1WHEA 3LIWB 3ZYJB 1CX2A 1G1QA 2W3KB 1PGEA 1LPKA 1NT0A 4RS0A 3BT1A 2W3IB 4Y6DB 1F0SB 4YZUB 1EGFA 1O5DL 1EPIA 1FAXL 2BQWA 2EI6B 1JL9A 1J9CL 5I46L 4RRYA 4G1MB 2WPLE 2XBYL 1BF9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Y79 B;  1JV2 B;  3KQB L;  4YT6 L;  3ASI A;  1HJ7 A;  2K2S B;  2P26 A;  3KQC L;  4ZHA B;  3CS7 L;  1M1X B;  1EAI C;  2B7D L;  4X8U L;  4JYU L;  4NA9 L;  3IJE B;  1EPH A;  1XFE A;  1DIY A;  4AQT A;  1NZI A;  5KIR A;  1QFK L;  1LPG A;  1G1T A;  2TGF A;  1IQE L;  4CUE A;  4C16 A;  3IIT B;  2MGR A;  4M11 A;  4X8V L;  1HX2 A;  2EI8 B;  2XC0 L;  3FBY A;  2KL7 A;  3N8Z A;  3FCS B;  1GK5 A;  2WG3 C;  1W8B L;  2BOK L;  4TGF A;  2VVV L;  2P3F N;  3LTF B;  1L3Y A;  4Y7A B;  4COX A;  2RA0 L;  3Q7D A;  5E8D A;  3ELA L;  3CA7 A;  3CFW A;  2XC5 L;  4BXS A;  2WPM E;  1WU1 B;  1ATD A;  1EZQ B;  3N8Y B;  1FSB A;  2VH6 B;  1TPG A;  1ATB A;  1NQL B;  1IQK L;  1C5M F;  2I9B A;  2W2O E;  3HS6 A;  4CUF A;  1SZB A;  1EBV A;  5K0H B;  4D90 A;  2P3F L;  1WHF A;  1EQG A;  3TZI A;  2VWN L;  1AUT L;  4BTU A;  3GCX E;  3DEM A;  3FFG L;  1IJQ A;  3TK6 B;  5IKV A;  4XLW A;  1IQN L;  2PHB B;  2P94 L;  1COU A;  5F19 A;  2Y80 B;  2FLR L;  2EI7 B;  2BQ7 A;  1N1I A;  1G2L B;  1FF7 A;  3V65 B;  1CCF A;  5L30 L;  1MQ5 L;  4X8T L;  1HT8 A;  3QMO A;  4LMF A;  4ZH8 B;  3HS5 A;  1YUG A;  3ENS A;  3N8V A;  1EMN A;  3OLT A;  4Y71 B;  2J34 B;  2VH0 B;  2P3T A;  3SW2 A;  1Z6C A;  3M37 L;  1IQG L;  5JBC E;  4OTJ A;  3KL6 B;  4X8S L;  4FM5 A;  2MHP A;  3HO4 A;  1MOX C;  2VVC K;  3H5C B;  2Y82 B;  2AYL A;  5IKR A;  2FLB L;  5L2Z L;  1FFM A;  4JYV L;  2KB9 A;  2FLG A;  2K2T A;  4BDX A;  1V3X B;  2RNL A;  2G00 L;  1UZK A;  1UZQ A;  3HO3 A;  1IQL L;  1URK A;  2WFX B;  6COX A;  2BO2 A;  3R05 A;  1G1S A;  4NG9 L;  4ZXY L;  1APO A;  1X7A L;  3F6U L;  4NGA L;  5JBB E;  2W86 A;  2J94 B;  3KRK A;  3MQE A;  4Y7B B;  1KLI L;  3NTB A;  3SOQ A;  1NFY B;  1CVU A;  2NPR A;  4BTI A;  4O1Z A;  4XBM A;  3TGF A;  1Z6E L;  2BOX A;  2Y38 A;  2D1J B;  2F9B L;  4ISH L;  3ZYG A;  1IGX A;  5JB8 E;  1I0U A;  1HT5 A;  2MGP A;  1IOE L;  4RRW A;  2P95 L;  1JBU L;  2BZ6 L;  1ATA A;  2RHP A;  1HRE A;  4BXW A;  1APQ A;  1IOX A;  3M36 L;  3PGH A;  4Z0K B;  1W7X L;  1HZ8 A;  2Y7X B;  2ADX A;  3HPT A;  3HS7 A;  1XKA L;  1PTH A;  2W2N E;  2M74 A;  5JVY A;  1LQD A;  3SOB B;  2WPK E;  1KLJ L;  2J38 B;  1NFX B;  1UZP A;  3Q3K B;  4BDW A;  1G1R A;  1KSN B;  2WPH E;  4OTY A;  1P9J A;  1IGZ A;  2XBW L;  5JVZ A;  2WYJ B;  2W26 B;  1FAK L;  2Y5F L;  2P3U A;  5COX A;  1F0R B;  5CKQ A;  3MDL A;  5JB9 E;  2UWO B;  2DDU A;  2Y81 B;  4JZD L;  3RR3 A;  1TLE A;  4JZF L;  1YUK B;  4D0E A;  3QCW A;  1EQH A;  3BT2 A;  1HAF A;  2H9E L;  1IQH L;  4RRZ A;  2P93 L;  2YGP A;  3V64 C;  3OLU A;  4JZE L;  3NT1 A;  5FDQ A;  1OB1 C;  3NTG A;  3TH3 L;  1B9W A;  3F1S B;  1KLO A;  3LTG D;  4ZXX L;  2XBV L;  2BOH A;  3EGF A;  1IQM L;  2P16 L;  1ATE A;  1HAE A;  2YGO A;  1PXX A;  1LMJ A;  1YO8 A;  3GCW E;  2Q1J B;  3LN1 A;  2VVU L;  3U7U G;  1KIG L;  4Z0L A;  2J2U B;  1FE2 A;  4O02 B;  2XBX L;  1A3P A;  4ZAE B;  2CJI B;  5F1A A;  3LAQ A;  3LC5 B;  1K36 A;  3SOV A;  2OYU P;  3KK6 A;  4MMY B;  1P0S L;  1U8C B;  1MQ6 L;  2W2Q E;  3TBD A;  2Y5G L;  5JW1 A;  2WFT A;  2JKH L;  4LOR A;  1XDT R;  1ADX A;  4RRX A;  4A7I A;  3CEN L;  1CVW L;  1CCV A;  3K9X A;  3KQD L;  4E1G A;  2GD4 A;  1DDX A;  1UZJ A;  1IVO C;  2VJ3 A;  1LPZ A;  4ISI L;  3BPS E;  4RUT A;  5CKM A;  1G2M B;  2Y7Z B;  2W2M E;  2UWP B;  4D0F A;  4CUD A;  4M10 A;  1F7E A;  2PUQ L;  4PH9 A;  1CQE A;  1ZAQ A;  4Y76 B;  1U67 A;  3N8X A;  1RFN B;  1F7M A;  2W2P E;  2BOU A;  2VWO L;  4MMX B;  1N7D A;  1XKB A;  1K37 A;  1EMO A;  2J4I B;  5CIS A;  1HCG B;  1NFU B;  3HO5 A;  2WG4 B;  2I9A A;  4XL1 A;  4CSY A;  1Q4G A;  2UWL B;  3QH0 A;  5JBA E;  4BTT A;  1IQF L;  1NFW B;  3LN0 A;  3KCG L;  2WYG B;  1CEJ A;  3LC3 B;  3N8Y A;  2WPI E;  1IP0 A;  4YT7 L;  2PR3 B;  5KN5 C;  2FD6 A;  4Z6A L;  5IKT A;  1EPG A;  4MMZ B;  3GIS X;  1YUF A;  2P28 B;  5EGM B;  2VWM K;  1L5G B;  3NJP C;  1HRF A;  2XC4 L;  3N8W B;  2KV4 A;  1IQJ L;  1IQI L;  2BMG A;  5IKQ A;  2WPJ E;  3N8W A;  3TK5 B;  3KQE L;  3C9A C;  3ZYI B;  1YGC L;  1DX5 I;  3POY A;  1NPE B;  1PFX L;  5L2Y L;  2Y5H L;  3U73 A;  3P5B L;  2FZZ L;  1PRH A;  1FJS L;  2BQ6 A;  2J95 B;  2VWL L;  1DQB A;  1DVA L;  1TOZ A;  2OYE P;  5CKN A;  1EPJ A;  1WHE A;  3LIW B;  3ZYJ B;  1CX2 A;  1G1Q A;  2W3K B;  1PGE A;  1LPK A;  1NT0 A;  4RS0 A;  3BT1 A;  2W3I B;  4Y6D B;  1F0S B;  4YZU B;  1EGF A;  1O5D L;  1EPI A;  1FAX L;  2BQW A;  2EI6 B;  1JL9 A;  1J9C L;  5I46 L;  4RRY A;  4G1M B;  2WPL E;  2XBY L;  1BF9 A; 
#chains in the Genus database with same CATH topology
 4Y79 B;  1JV2 B;  3KQB L;  4YT6 L;  3ASI A;  1HJ7 A;  2K2S B;  2P26 A;  3KQC L;  1V1I A;  4ZHA B;  3CS7 L;  1M1X B;  1EAI C;  2B7D L;  4X8U L;  4JYU L;  4NA9 L;  3IJE B;  1EPH A;  1XFE A;  1DIY A;  4AQT A;  1NZI A;  5KIR A;  1QFK L;  1LMM A;  1LPG A;  1G1T A;  2TGF A;  1IQE L;  4CUE A;  4C16 A;  3IIT B;  2MGR A;  4M11 A;  2BSF A;  2JJL A;  4X8V L;  1HX2 A;  2EI8 B;  2XC0 L;  2YGQ A;  3FBY A;  2KL7 A;  3N8Z A;  3FCS B;  1GK5 A;  2WG3 C;  1W8B L;  2BOK L;  4TGF A;  2VVV L;  2P3F N;  3LTF B;  1L3Y A;  4Y7A B;  4COX A;  2RA0 L;  3Q7D A;  5E8D A;  3ELA L;  3CA7 A;  3CFW A;  2XC5 L;  4BXS A;  2WPM E;  1WU1 B;  1ATD A;  1EZQ B;  3N8Y B;  1KKE A;  2VH6 B;  1TPG A;  1FSB A;  1ATB A;  1NQL B;  2H9E C;  1IQK L;  1C5M F;  2I9B A;  2W2O E;  3HS6 A;  4CUF A;  1SZB A;  1EBV A;  3S6X A;  5K0H B;  4D90 A;  2P3F L;  1WHF A;  4A94 C;  1EQG A;  3TZI A;  2VWN L;  1AUT L;  4BTU A;  3GCX E;  3DEM A;  3FFG L;  1IJQ A;  3TK6 B;  5IKV A;  4XLW A;  1IQN L;  2WZP P;  2PHB B;  2P94 L;  1COU A;  5F19 A;  2Y80 B;  2FLR L;  2EI7 B;  2BQ7 A;  1N1I A;  1G2L B;  1FF7 A;  3V65 B;  1CCF A;  5L30 L;  1MQ5 L;  4X8T L;  1HT8 A;  3QMO A;  4LMF A;  4ZH8 B;  3HS5 A;  1YUG A;  3ENS A;  3N8V A;  1EMN A;  3OLT A;  4Y71 B;  2J34 B;  2VH0 B;  2P3T A;  3SW2 A;  1Z6C A;  3M37 L;  1IQG L;  5JBC E;  4OTJ A;  3KL6 B;  4X8S L;  4FM5 A;  2MHP A;  3HO4 A;  1MOX C;  2VVC K;  3H5C B;  2Y82 B;  2AYL A;  5IKR A;  2FLB L;  5L2Z L;  1FFM A;  2KNI A;  4JYV L;  2KB9 A;  2FLG A;  2K2T A;  4BDX A;  1V3X B;  2HOX A;  2RNL A;  2G00 L;  1UZK A;  1UZQ A;  3HO3 A;  1IQL L;  1URK A;  4GU3 A;  2WFX B;  6COX A;  2BO2 A;  3R05 A;  4GU4 A;  1G1S A;  4NG9 L;  4ZXY L;  1APO A;  1X7A L;  3F6U L;  4NGA L;  5JBB E;  2W86 A;  2J94 B;  3KRK A;  3MQE A;  4Y7B B;  1KLI L;  3NTB A;  3SOQ A;  1NFY B;  1CVU A;  2NPR A;  4BTI A;  4O1Z A;  4XBM A;  3TGF A;  1Z6E L;  2BOX A;  2Y38 A;  2D1J B;  2F9B L;  4ISH L;  3ZYG A;  1IGX A;  5JB8 E;  1I0U A;  1HT5 A;  2MGP A;  1IOE L;  4RRW A;  2P95 L;  1JBU L;  2BZ6 L;  1ATA A;  2RHP A;  1HRE A;  4BXW A;  1APQ A;  1IOX A;  3M36 L;  3PGH A;  4Z0K B;  1W7X L;  1HZ8 A;  2Y7X B;  2ADX A;  3HPT A;  3HS7 A;  1XKA L;  1PTH A;  2W2N E;  2M74 A;  5JVY A;  2HOR A;  1LQD A;  3SOB B;  2WPK E;  1KLJ L;  2J38 B;  1NFX B;  1UZP A;  3Q3K B;  4BDW A;  1G1R A;  1KSN B;  2WPH E;  4OTY A;  1P9J A;  1IGZ A;  2XBW L;  5JVZ A;  2WYJ B;  2W26 B;  1FAK L;  2Y5F L;  2P3U A;  5COX A;  1F0R B;  5CKQ A;  3MDL A;  5JB9 E;  2UWO B;  2DDU A;  2Y81 B;  4JZD L;  3RR3 A;  1TLE A;  4JZF L;  1YUK B;  4D0E A;  3QCW A;  1EQH A;  3BT2 A;  1HAF A;  2H9E L;  1IQH L;  4RRZ A;  2P93 L;  2YGP A;  3V64 C;  3OLU A;  4JZE L;  3NT1 A;  5FDQ A;  1OB1 C;  3NTG A;  3TH3 L;  1B9W A;  3F1S B;  1KLO A;  3LTG D;  4ZXX L;  2XBV L;  1QIU A;  2BOH A;  3EGF A;  1IQM L;  2P16 L;  1ATE A;  1HAE A;  2YGO A;  1PXX A;  1LMJ A;  1YO8 A;  3GCW E;  2Q1J B;  3LN1 A;  2VVU L;  3U7U G;  1KIG L;  4Z0L A;  2J2U B;  1FE2 A;  4O02 B;  2XBX L;  1A3P A;  1V1H A;  4ZAE B;  2CJI B;  5F1A A;  3LAQ A;  3LC5 B;  1K36 A;  3SOV A;  2OYU P;  3KK6 A;  4MMY B;  1P0S L;  1U8C B;  1MQ6 L;  2W2Q E;  3TBD A;  2Y5G L;  5JW1 A;  2WFT A;  2JKH L;  4LOR A;  1XDT R;  1ADX A;  4RRX A;  4A7I A;  3CEN L;  1CVW L;  1CCV A;  3K9X A;  3KQD L;  4E1G A;  2GD4 A;  1DDX A;  1UZJ A;  1IVO C;  2VJ3 A;  1LPZ A;  4ISI L;  3BPS E;  4RUT A;  5CKM A;  1G2M B;  2Y7Z B;  2W2M E;  2UWP B;  4D0F A;  4CUD A;  4M10 A;  1F7E A;  2PUQ L;  4PH9 A;  1CQE A;  1ZAQ A;  4Y76 B;  1U67 A;  3N8X A;  1RFN B;  1F7M A;  2W2P E;  2BOU A;  2VWO L;  4MMX B;  1N7D A;  1XKB A;  1K37 A;  1EMO A;  2J4I B;  5CIS A;  1LK9 A;  1HCG B;  1NFU B;  3HO5 A;  2WG4 B;  2I9A A;  4XL1 A;  4CSY A;  1Q4G A;  2UWL B;  3QH0 A;  2BT7 A;  5JBA E;  4BTT A;  1IQF L;  1NFW B;  3LN0 A;  3KCG L;  2WYG B;  1CEJ A;  3LC3 B;  3N8Y A;  2WPI E;  1IP0 A;  4YT7 L;  2PR3 B;  5KN5 C;  2FD6 A;  4Z6A L;  5IKT A;  1EPG A;  4MMZ B;  3GIS X;  1YUF A;  2P28 B;  5EGM B;  2VWM K;  1L5G B;  3NJP C;  1HRF A;  2XC4 L;  3N8W B;  2KV4 A;  1IQJ L;  1IQI L;  2BMG A;  5IKQ A;  2WPJ E;  3N8W A;  3TK5 B;  3KQE L;  3C9A C;  3ZYI B;  1YGC L;  1DX5 I;  3POY A;  1NPE B;  1PFX L;  5L2Y L;  2Y5H L;  3U73 A;  3P5B L;  2FZZ L;  1PRH A;  1FJS L;  2BT8 A;  2VRS A;  2BQ6 A;  2J95 B;  2VWL L;  1DQB A;  1DVA L;  1TOZ A;  2OYE P;  5CKN A;  1EPJ A;  1WHE A;  3LIW B;  3ZYJ B;  1CX2 A;  1G1Q A;  2W3K B;  1PGE A;  1LPK A;  1NT0 A;  4RS0 A;  3BT1 A;  2W3I B;  4Y6D B;  1F0S B;  4YZU B;  1EGF A;  1O5D L;  1EPI A;  1FAX L;  2BQW A;  2EI6 B;  1JL9 A;  1J9C L;  5I46 L;  4RRY A;  4G1M B;  2WPL E;  2XBY L;  1BF9 A; 
#chains in the Genus database with same CATH homology
 4Y79 B;  1JV2 B;  3KQB L;  4YT6 L;  3ASI A;  1HJ7 A;  2K2S B;  2P26 A;  3KQC L;  4ZHA B;  3CS7 L;  1M1X B;  1EAI C;  2B7D L;  4X8U L;  4JYU L;  4NA9 L;  3IJE B;  1EPH A;  1XFE A;  1DIY A;  4AQT A;  1NZI A;  5KIR A;  1QFK L;  1LMM A;  1LPG A;  1G1T A;  2TGF A;  1IQE L;  4CUE A;  4C16 A;  3IIT B;  2MGR A;  4M11 A;  4X8V L;  1HX2 A;  2EI8 B;  2XC0 L;  2YGQ A;  3FBY A;  2KL7 A;  3N8Z A;  3FCS B;  1GK5 A;  2WG3 C;  1W8B L;  2BOK L;  4TGF A;  2VVV L;  2P3F N;  3LTF B;  1L3Y A;  4Y7A B;  4COX A;  2RA0 L;  3Q7D A;  5E8D A;  3ELA L;  3CA7 A;  3CFW A;  2XC5 L;  4BXS A;  2WPM E;  1WU1 B;  1ATD A;  1EZQ B;  3N8Y B;  1FSB A;  2VH6 B;  1TPG A;  1ATB A;  1NQL B;  2H9E C;  1IQK L;  1C5M F;  2I9B A;  2W2O E;  3HS6 A;  4CUF A;  1SZB A;  1EBV A;  3S6X A;  5K0H B;  4D90 A;  2P3F L;  1WHF A;  4A94 C;  1EQG A;  3TZI A;  2VWN L;  1AUT L;  4BTU A;  3GCX E;  3DEM A;  3FFG L;  1IJQ A;  3TK6 B;  5IKV A;  4XLW A;  1IQN L;  2WZP P;  2PHB B;  2P94 L;  1COU A;  5F19 A;  2Y80 B;  2FLR L;  2EI7 B;  2BQ7 A;  1N1I A;  1G2L B;  1FF7 A;  3V65 B;  1CCF A;  5L30 L;  1MQ5 L;  4X8T L;  1HT8 A;  3QMO A;  4LMF A;  4ZH8 B;  3HS5 A;  1YUG A;  3ENS A;  3N8V A;  1EMN A;  3OLT A;  4Y71 B;  2J34 B;  2VH0 B;  2P3T A;  3SW2 A;  1Z6C A;  3M37 L;  1IQG L;  5JBC E;  4OTJ A;  3KL6 B;  4X8S L;  4FM5 A;  2MHP A;  3HO4 A;  1MOX C;  2VVC K;  3H5C B;  2Y82 B;  2AYL A;  5IKR A;  2FLB L;  5L2Z L;  1FFM A;  2KNI A;  4JYV L;  2KB9 A;  2FLG A;  2K2T A;  4BDX A;  1V3X B;  2RNL A;  2G00 L;  1UZK A;  1UZQ A;  3HO3 A;  1IQL L;  1URK A;  2WFX B;  6COX A;  2BO2 A;  3R05 A;  1G1S A;  4NG9 L;  4ZXY L;  1APO A;  1X7A L;  3F6U L;  4NGA L;  5JBB E;  2W86 A;  2J94 B;  3KRK A;  3MQE A;  4Y7B B;  1KLI L;  3NTB A;  3SOQ A;  1NFY B;  1CVU A;  2NPR A;  4BTI A;  4O1Z A;  4XBM A;  3TGF A;  1Z6E L;  2BOX A;  2Y38 A;  2D1J B;  2F9B L;  4ISH L;  3ZYG A;  1IGX A;  5JB8 E;  1I0U A;  1HT5 A;  2MGP A;  1IOE L;  4RRW A;  2P95 L;  1JBU L;  2BZ6 L;  1ATA A;  2RHP A;  1HRE A;  4BXW A;  1APQ A;  1IOX A;  3M36 L;  3PGH A;  4Z0K B;  1W7X L;  1HZ8 A;  2Y7X B;  2ADX A;  3HPT A;  3HS7 A;  1XKA L;  1PTH A;  2W2N E;  2M74 A;  5JVY A;  1LQD A;  3SOB B;  2WPK E;  1KLJ L;  2J38 B;  1NFX B;  1UZP A;  3Q3K B;  4BDW A;  1G1R A;  1KSN B;  2WPH E;  4OTY A;  1P9J A;  1IGZ A;  2XBW L;  5JVZ A;  2WYJ B;  2W26 B;  1FAK L;  2Y5F L;  2P3U A;  5COX A;  1F0R B;  5CKQ A;  3MDL A;  5JB9 E;  2UWO B;  2DDU A;  2Y81 B;  4JZD L;  3RR3 A;  1TLE A;  4JZF L;  1YUK B;  4D0E A;  3QCW A;  1EQH A;  3BT2 A;  1HAF A;  2H9E L;  1IQH L;  4RRZ A;  2P93 L;  2YGP A;  3V64 C;  3OLU A;  4JZE L;  3NT1 A;  5FDQ A;  1OB1 C;  3NTG A;  3TH3 L;  1B9W A;  3F1S B;  1KLO A;  3LTG D;  4ZXX L;  2XBV L;  2BOH A;  3EGF A;  1IQM L;  2P16 L;  1ATE A;  1HAE A;  2YGO A;  1PXX A;  1LMJ A;  1YO8 A;  3GCW E;  2Q1J B;  3LN1 A;  2VVU L;  3U7U G;  1KIG L;  4Z0L A;  2J2U B;  1FE2 A;  4O02 B;  2XBX L;  1A3P A;  4ZAE B;  2CJI B;  5F1A A;  3LAQ A;  3LC5 B;  1K36 A;  3SOV A;  2OYU P;  3KK6 A;  4MMY B;  1P0S L;  1U8C B;  1MQ6 L;  2W2Q E;  3TBD A;  2Y5G L;  5JW1 A;  2WFT A;  2JKH L;  4LOR A;  1XDT R;  1ADX A;  4RRX A;  4A7I A;  3CEN L;  1CVW L;  1CCV A;  3K9X A;  3KQD L;  4E1G A;  2GD4 A;  1DDX A;  1UZJ A;  1IVO C;  2VJ3 A;  1LPZ A;  4ISI L;  3BPS E;  4RUT A;  5CKM A;  1G2M B;  2Y7Z B;  2W2M E;  2UWP B;  4D0F A;  4CUD A;  4M10 A;  1F7E A;  2PUQ L;  4PH9 A;  1CQE A;  1ZAQ A;  4Y76 B;  1U67 A;  3N8X A;  1RFN B;  1F7M A;  2W2P E;  2BOU A;  2VWO L;  4MMX B;  1N7D A;  1XKB A;  1K37 A;  1EMO A;  2J4I B;  5CIS A;  1HCG B;  1NFU B;  3HO5 A;  2WG4 B;  2I9A A;  4XL1 A;  4CSY A;  1Q4G A;  2UWL B;  3QH0 A;  5JBA E;  4BTT A;  1IQF L;  1NFW B;  3LN0 A;  3KCG L;  2WYG B;  1CEJ A;  3LC3 B;  3N8Y A;  2WPI E;  1IP0 A;  4YT7 L;  2PR3 B;  5KN5 C;  2FD6 A;  4Z6A L;  5IKT A;  1EPG A;  4MMZ B;  3GIS X;  1YUF A;  2P28 B;  5EGM B;  2VWM K;  1L5G B;  3NJP C;  1HRF A;  2XC4 L;  3N8W B;  2KV4 A;  1IQJ L;  1IQI L;  2BMG A;  5IKQ A;  2WPJ E;  3N8W A;  3TK5 B;  3KQE L;  3C9A C;  3ZYI B;  1YGC L;  1DX5 I;  3POY A;  1NPE B;  1PFX L;  5L2Y L;  2Y5H L;  3U73 A;  3P5B L;  2FZZ L;  1PRH A;  1FJS L;  2BQ6 A;  2J95 B;  2VWL L;  1DQB A;  1DVA L;  1TOZ A;  2OYE P;  5CKN A;  1EPJ A;  1WHE A;  3LIW B;  3ZYJ B;  1CX2 A;  1G1Q A;  2W3K B;  1PGE A;  1LPK A;  1NT0 A;  4RS0 A;  3BT1 A;  2W3I B;  4Y6D B;  1F0S B;  4YZU B;  1EGF A;  1O5D L;  1EPI A;  1FAX L;  2BQW A;  2EI6 B;  1JL9 A;  1J9C L;  5I46 L;  4RRY A;  4G1M B;  2WPL E;  2XBY L;  1BF9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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