4NG9L

Factor viia in complex with the inhibitor (2r)-2-[(1-aminoisoquinolin-6-yl)amino]-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-n-(3-sulfamoylbenzyl)ethanamide
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
55
structure length
54
Chain Sequence
ICVNENGGCEQYCSDHTGKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design and Synthesis of Phenylpyrrolidine Phenylglycinamides As Highly Potent and Selective TF-FVIIa Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Factor VIIa (Heavy Chain)
total genus 12
structure length 54
sequence length 55
ec nomenclature ec 3.4.21.21: Coagulation factor VIIa.
pdb deposition date 2013-11-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 4ng9L00
1HX2A 1NFXB 1YO8A 4ZHAB 2XBXL 1F0RB 2W3KB 3QH0A 2F9BL 5JB8E 1XKBA 3HO4A 1ATAA 1FF7A 2MGPA 1EQHA 1IP0A 4COXA 1FSBA 4FM5A 2XBVL 4JYUL 3Q7DA 2JKHL 3CFWA 2BQ7A 4TGFA 1HJ7A 1IQKL 2WG3C 4BTUA 4XBMA 3KQBL 1CQEA 1IOXA 3HO5A 1ATDA 3GCWE 2DDUA 3EGFA 3N8YB 1IQNL 1ZAQA 3KQDL 2P3FN 2WPME 2VH0B 1Z6EL 1YUFA 4YT7L 2WYJB 4Z0KB 1EMNA 4BDXA 4D90A 4BXWA 3LN1A 2KV4A 4Y76B 5L2ZL 2P95L 2D1JB 4CUFA 1IGXA 2G00L 1CEJA 3LC5B 3ZYJB 2PR3B 1F0SB 3FFGL 1B9WA 1CX2A 2K2TA 1LMJA 3V64C 4Y6DB 1C5MF 2OYUP 4CUDA 1LQDA 4BXSA 5IKRA 1CVWL 2WPLE 3ZYIB 1IQML 1PXXA 3SW2A 1JV2B 2WPKE 1LPKA 4RS0A 3FBYA 1HRFA 2TGFA 3PGHA 5EGMB 2WYGB 2UWOB 2XC0L 3LAQA 2J34B 5L2YL 1W8BL 5L30L 3U7UG 1OB1C 1DDXA 3N8YA 1J9CL 1G2LB 1EPHA 4M10A 4ZAEB 5KIRA 3MDLA 5I46L 4RRXA 2VVCK 1YUGA 1NFYB 2W2ME 2H9EL 3KRKA 3KL6B 3LTFB 1P0SL 2CJIB 2P3UA 3QMOA 2EI6B 1APQA 4MMZB 2J95B 2VWNL 3N8XA 1COUA 4ZXXL 1F7EA 2FLBL 1EGFA 2WG4B 1EMOA 4RUTA 1QFKL 4X8TL 3F6UL 3RR3A 3Q3KB 4MMXB 1CCVA 2AYLA 3P5BL 1IQIL 1W7XL 2Y5FL 1IQGL 2VVUL 1PTHA 4JZFL 1X7AL 3TBDA 2P3FL 2B7DL 1PRHA 1KLOA 4E1GA 1WHFA 4D0EA 3SOQA 3V65B 3LN0A 1EQGA 1UZQA 1XFEA 1F7MA 2FD6A 2WPJE 1HT5A 1FAKL 1PFXL 3KQCL 1URKA 2VWLL 3IITB 1DQBA 3M36L 1EZQB 2J38B 1KLIL 3BT2A 3HO3A 3LC3B 1G1RA 1WU1B 4AQTA 4Y79B 3POYA 5COXA 2EI8B 3ELAL 1HAFA 4CSYA 1EPIA 1G1TA 2VJ3A 2NPRA 1IQFL 4BDWA 2Y7XB 4JYVL 1IQEL 3LIWB 5JBAE 5CISA 5IKVA 1HT8A 4PH9A 1NZIA 5F19A 1L5GB 4MMYB 2Y38A 2FLGA 1Z6CA 3TK6B 5JBBE 4D0FA 2BO2A 2W2NE 1CVUA 3NTGA 1IQJL 1IJQA 1IOEL 2I9BA 4BTTA 1YUKB 2UWLB 1YGCL 1M1XB 2Y80B 1K36A 4C16A 1HZ8A 1G1QA 2PHBB 3ZYGA 3F1SB 2BZ6L 1V3XB 1IQLL 4ISIL 2BMGA 2VVVL 4YT6L 2RHPA 4Y71B 1IQHL 3HS5A 1L3YA 1FFMA 2XC5L 3N8WB 1IVOC 4Z0LA 2P93L 4Y7AB 3NJPC 3U73A 2I9AA 1N1IA 1O5DL 2BQ6A 2J2UB 2Y81B 2VWOL 4ISHL 3ASIA 1NT0A 5CKNA 2M74A 3TZIA 1SZBA 2YGPA 4O1ZA 5IKTA 2P3TA 4OTYA 2UWPB 3GCXE 3DEMA 5JW1A 1JL9A 5K0HB 2RNLA 4A7IA 1N7DA 4Y7BB 3BPSE 5JB9E 4Z6AL 1FJSL 2MGRA 2BOUA 3M37L 1DIYA 2BQWA 1UZPA 2VWMK 1AUTL 4X8SL 4CUEA 3N8WA 6COXA 1BF9A 4BTIA 4X8VL 1WHEA 1FE2A 2W2OE 1APOA 3R05A 1UZKA 1ATBA 2BOHA 4JZEL 2VH6B 2Y5HL 2KB9A 1EAIC 3KK6A 5FDQA 5KN5C 1I0UA 3OLUA 1ADXA 1TOZA 1KSNB 4YZUB 4G1MB 3HPTA 3N8VA 1KIGL 2PUQL 5JVZA 5E8DA 2XBWL 2Y82B 1CCFA 5CKQA 3SOBB 3FCSB 3OLTA 3TH3L 3C9AC 3BT1A 5CKMA 1P9JA 3H5CB 1FAXL 1NFWB 3TK5B 1A3PA 1ATEA 2GD4A 4OTJA 2Y7ZB 3KCGL 1G1SA 1EPJA 1K37A 5F1AA 3CENL 4JZDL 4XLWA 5JBCE 4NG9L 1EBVA 2BOXA 2P28B 2W3IB 1U8CB 4XL1A 4RRYA 3TGFA 1MQ6L 1DVAL 1TPGA 2P16L 1XKAL 2WFTA 4X8UL 2J94B 3GISX 3LTGD 4LORA 2RA0L 3CS7L 4O02B 4NA9L 2XBYL 4LMFA 3CA7A 4RRWA 2P94L 2WPHE 2EI7B 1EPGA 3K9XA 3N8ZA 1PGEA 1RFNB 1NPEB 2WPIE 1LPGA 2ADXA 2OYEP 2Q1JB 2BOKL 1KLJL 4RRZA 2K2SB 2KL7A 3QCWA 1MOXC 2MHPA 2W86A 1HAEA 2WFXB 1Q4GA 2FZZL 1NFUB 2W2PE 2P26A 1MQ5L 3NTBA 1JBUL 1G2MB 1HCGB 1UZJA 3HS6A 5JVYA 1DX5I 2XC4L 2YGOA 4ZXYL 1HREA 2J4IB 1NQLB 3HS7A 1LPZA 2W2QE 4M11A 1U67A 3SOVA 2Y5GL 3ENSA 4NGAL 3MQEA 3IJEB 4ZH8B 2W26B 1GK5A 1IGZA 3NT1A 2FLRL 1XDTR 3KQEL 1TLEA 5IKQA
chains in the Genus database with same CATH superfamily
1HX2A 1NFXB 1YO8A 2YGQA 2XBXL 4ZHAB 1F0RB 2W3KB 3QH0A 2F9BL 4A94C 5JB8E 1XKBA 3HO4A 1ATAA 1FF7A 2MGPA 1EQHA 1IP0A 1V1HA 2BT8A 4COXA 1FSBA 4FM5A 2XBVL 4JYUL 1QIUA 3Q7DA 1V1IA 2JKHL 3CFWA 2BQ7A 4TGFA 1HJ7A 1IQKL 2WG3C 4BTUA 4XBMA 3KQBL 1CQEA 1IOXA 3HO5A 1ATDA 3GCWE 2DDUA 3EGFA 3N8YB 1IQNL 1ZAQA 3KQDL 2P3FN 2WPME 2VH0B 1Z6EL 1YUFA 4YT7L 2WYJB 4Z0KB 1EMNA 4BDXA 4D90A 4BXWA 3LN1A 2KV4A 4Y76B 5L2ZL 2P95L 2D1JB 4CUFA 1IGXA 2G00L 1CEJA 3LC5B 3ZYJB 2PR3B 1F0SB 3FFGL 1B9WA 1CX2A 2K2TA 1LMJA 3V64C 4Y6DB 1C5MF 2OYUP 4CUDA 1LQDA 4BXSA 5IKRA 1CVWL 2WPLE 3ZYIB 1IQML 1PXXA 3SW2A 1JV2B 2BT7A 2WPKE 1LPKA 4RS0A 3FBYA 1HRFA 2TGFA 3PGHA 5EGMB 2WYGB 2UWOB 2XC0L 3LAQA 2J34B 5L2YL 1W8BL 5L30L 3U7UG 1OB1C 1DDXA 3N8YA 1J9CL 1G2LB 1EPHA 4M10A 4ZAEB 5KIRA 3MDLA 5I46L 4RRXA 2VVCK 1YUGA 1NFYB 2W2ME 2H9EL 3KRKA 3KL6B 3LTFB 1P0SL 2CJIB 2P3UA 3QMOA 2EI6B 1APQA 4MMZB 2J95B 2VWNL 3N8XA 1COUA 4ZXXL 1F7EA 2FLBL 1EGFA 2WG4B 1EMOA 4RUTA 1QFKL 1LMMA 4X8TL 3F6UL 3RR3A 3Q3KB 4MMXB 2VRSA 2AYLA 1CCVA 2KNIA 3P5BL 1IQIL 1W7XL 2Y5FL 1IQGL 2VVUL 1PTHA 4JZFL 1X7AL 3TBDA 2P3FL 2B7DL 1PRHA 1KLOA 4E1GA 1WHFA 4D0EA 3SOQA 3V65B 3LN0A 1EQGA 1UZQA 1XFEA 1F7MA 2FD6A 2WPJE 1HT5A 1FAKL 1PFXL 3KQCL 1URKA 2VWLL 3IITB 1DQBA 3M36L 1EZQB 2J38B 1KLIL 3BT2A 3HO3A 3LC3B 1G1RA 1WU1B 4AQTA 4Y79B 3POYA 5COXA 2EI8B 2BSFA 3ELAL 1HAFA 4CSYA 1EPIA 1G1TA 2VJ3A 2NPRA 1IQFL 4BDWA 2Y7XB 4JYVL 2JJLA 1IQEL 3LIWB 5JBAE 5CISA 5IKVA 1HT8A 4PH9A 1NZIA 5F19A 1L5GB 1KKEA 2Y38A 2FLGA 4MMYB 1Z6CA 3TK6B 4GU3A 5JBBE 4D0FA 2BO2A 2W2NE 1CVUA 3NTGA 1IQJL 1IJQA 1IOEL 2I9BA 4BTTA 1YUKB 2UWLB 1YGCL 1M1XB 2Y80B 1K36A 4C16A 1HZ8A 1G1QA 2PHBB 3ZYGA 3F1SB 2BZ6L 1V3XB 1IQLL 4ISIL 2BMGA 2VVVL 4YT6L 2RHPA 4Y71B 1IQHL 3HS5A 1L3YA 1FFMA 2XC5L 3N8WB 1IVOC 4Z0LA 2P93L 4Y7AB 3NJPC 3U73A 2I9AA 1N1IA 1O5DL 2BQ6A 2J2UB 2Y81B 2VWOL 4ISHL 3ASIA 1NT0A 5CKNA 1LK9A 2M74A 3TZIA 1SZBA 2YGPA 4O1ZA 2WZPP 5IKTA 2P3TA 4OTYA 2UWPB 3GCXE 3DEMA 5JW1A 1JL9A 5K0HB 2RNLA 4A7IA 1N7DA 4Y7BB 3BPSE 5JB9E 4Z6AL 1FJSL 2MGRA 2HORA 2BOUA 3M37L 1DIYA 2BQWA 1UZPA 2VWMK 1AUTL 4X8SL 4CUEA 3N8WA 6COXA 1BF9A 4BTIA 4X8VL 1WHEA 1FE2A 2W2OE 1APOA 3R05A 1UZKA 1ATBA 2BOHA 4JZEL 2VH6B 2Y5HL 2KB9A 1EAIC 3KK6A 5FDQA 5KN5C 1I0UA 3OLUA 1ADXA 1TOZA 1KSNB 4YZUB 4G1MB 3HPTA 3N8VA 1KIGL 2PUQL 5JVZA 5E8DA 2XBWL 2Y82B 1CCFA 5CKQA 3SOBB 3FCSB 3OLTA 3TH3L 3C9AC 3BT1A 4GU4A 5CKMA 1P9JA 3H5CB 1FAXL 1NFWB 3TK5B 1A3PA 1ATEA 2GD4A 4OTJA 2Y7ZB 3KCGL 1G1SA 1EPJA 1K37A 5F1AA 3CENL 4JZDL 4XLWA 5JBCE 4NG9L 1EBVA 2BOXA 2P28B 2W3IB 1U8CB 4XL1A 4RRYA 3TGFA 1MQ6L 1DVAL 1TPGA 2P16L 1XKAL 2WFTA 4X8UL 2J94B 3GISX 3LTGD 4LORA 2RA0L 3CS7L 4O02B 4NA9L 2XBYL 4LMFA 3CA7A 4RRWA 2P94L 2WPHE 2EI7B 1EPGA 3K9XA 3N8ZA 1PGEA 1RFNB 1NPEB 2WPIE 1LPGA 2ADXA 3S6XA 2OYEP 2Q1JB 2BOKL 1KLJL 4RRZA 2K2SB 2KL7A 3QCWA 1MOXC 2MHPA 2W86A 1HAEA 2WFXB 1Q4GA 2FZZL 1NFUB 2W2PE 2P26A 1MQ5L 3NTBA 1JBUL 1G2MB 1HCGB 1UZJA 3HS6A 5JVYA 1DX5I 2XC4L 2YGOA 4ZXYL 1HREA 2H9EC 2J4IB 1NQLB 3HS7A 1LPZA 2W2QE 4M11A 1U67A 3SOVA 2Y5GL 3ENSA 4NGAL 3MQEA 3IJEB 4ZH8B 2HOXA 2W26B 1GK5A 1IGZA 3NT1A 2FLRL 1XDTR 3KQEL 1TLEA 5IKQA
chains in the Genus database with same CATH topology
1HX2A 1NFXB 1YO8A 2YGQA 2XBXL 4ZHAB 1F0RB 2W3KB 3QH0A 2F9BL 4A94C 5JB8E 1XKBA 3HO4A 1ATAA 1FF7A 2MGPA 1EQHA 1IP0A 4COXA 1FSBA 4FM5A 2XBVL 4JYUL 3Q7DA 2JKHL 3CFWA 2BQ7A 4TGFA 1HJ7A 1IQKL 2WG3C 4BTUA 4XBMA 3KQBL 1CQEA 1IOXA 3HO5A 1ATDA 3GCWE 2DDUA 3EGFA 3N8YB 1IQNL 1ZAQA 3KQDL 2P3FN 2WPME 2VH0B 1Z6EL 1YUFA 4YT7L 2WYJB 4Z0KB 1EMNA 4BDXA 4D90A 4BXWA 3LN1A 2KV4A 4Y76B 5L2ZL 2P95L 2D1JB 4CUFA 1IGXA 2G00L 1CEJA 3LC5B 3ZYJB 2PR3B 1F0SB 3FFGL 1B9WA 1CX2A 2K2TA 1LMJA 3V64C 4Y6DB 1C5MF 2OYUP 4CUDA 1LQDA 4BXSA 5IKRA 1CVWL 2WPLE 3ZYIB 1IQML 1PXXA 3SW2A 1JV2B 2WPKE 1LPKA 4RS0A 3FBYA 1HRFA 2TGFA 3PGHA 5EGMB 2WYGB 2UWOB 2XC0L 3LAQA 2J34B 5L2YL 1W8BL 5L30L 3U7UG 1OB1C 1DDXA 3N8YA 1J9CL 1G2LB 1EPHA 4M10A 4ZAEB 5KIRA 3MDLA 5I46L 4RRXA 2VVCK 1YUGA 1NFYB 2W2ME 2H9EL 3KRKA 3KL6B 3LTFB 1P0SL 2CJIB 2P3UA 3QMOA 2EI6B 1APQA 4MMZB 2J95B 2VWNL 3N8XA 1COUA 4ZXXL 1F7EA 2FLBL 1EGFA 2WG4B 1EMOA 4RUTA 1QFKL 1LMMA 4X8TL 3F6UL 3RR3A 3Q3KB 4MMXB 1CCVA 2AYLA 2KNIA 3P5BL 1IQIL 1W7XL 2Y5FL 1IQGL 2VVUL 1PTHA 4JZFL 1X7AL 3TBDA 2P3FL 2B7DL 1PRHA 1KLOA 4E1GA 1WHFA 4D0EA 3SOQA 3V65B 3LN0A 1EQGA 1UZQA 1XFEA 1F7MA 2FD6A 2WPJE 1HT5A 1FAKL 1PFXL 3KQCL 1URKA 2VWLL 3IITB 1DQBA 3M36L 1EZQB 2J38B 1KLIL 3BT2A 3HO3A 3LC3B 1G1RA 1WU1B 4AQTA 4Y79B 3POYA 5COXA 2EI8B 3ELAL 1HAFA 4CSYA 1EPIA 1G1TA 2VJ3A 2NPRA 1IQFL 4BDWA 2Y7XB 4JYVL 1IQEL 3LIWB 5JBAE 5CISA 5IKVA 1HT8A 4PH9A 1NZIA 5F19A 1L5GB 4MMYB 2Y38A 2FLGA 1Z6CA 3TK6B 5JBBE 4D0FA 2BO2A 2W2NE 1CVUA 3NTGA 1IQJL 1IJQA 1IOEL 2I9BA 4BTTA 1YUKB 2UWLB 1YGCL 1M1XB 2Y80B 1K36A 4C16A 1HZ8A 1G1QA 2PHBB 3ZYGA 3F1SB 2BZ6L 1V3XB 1IQLL 4ISIL 2BMGA 2VVVL 4YT6L 2RHPA 4Y71B 1IQHL 3HS5A 1L3YA 1FFMA 2XC5L 3N8WB 1IVOC 4Z0LA 2P93L 4Y7AB 3NJPC 3U73A 2I9AA 1N1IA 1O5DL 2BQ6A 2J2UB 2Y81B 2VWOL 4ISHL 3ASIA 1NT0A 5CKNA 2M74A 3TZIA 1SZBA 2YGPA 4O1ZA 2WZPP 5IKTA 2P3TA 4OTYA 2UWPB 3GCXE 3DEMA 5JW1A 1JL9A 5K0HB 2RNLA 4A7IA 1N7DA 4Y7BB 3BPSE 5JB9E 4Z6AL 1FJSL 2MGRA 2BOUA 3M37L 1DIYA 2BQWA 1UZPA 2VWMK 1AUTL 4X8SL 4CUEA 3N8WA 6COXA 1BF9A 4BTIA 4X8VL 1WHEA 1FE2A 2W2OE 1APOA 3R05A 1UZKA 1ATBA 2BOHA 4JZEL 2VH6B 2Y5HL 2KB9A 1EAIC 3KK6A 5FDQA 5KN5C 1I0UA 3OLUA 1ADXA 1TOZA 1KSNB 4YZUB 4G1MB 3HPTA 3N8VA 1KIGL 2PUQL 5JVZA 5E8DA 2XBWL 2Y82B 1CCFA 5CKQA 3SOBB 3FCSB 3OLTA 3TH3L 3C9AC 3BT1A 5CKMA 1P9JA 3H5CB 1FAXL 1NFWB 3TK5B 1A3PA 1ATEA 2GD4A 4OTJA 2Y7ZB 3KCGL 1G1SA 1EPJA 1K37A 5F1AA 3CENL 4JZDL 4XLWA 5JBCE 4NG9L 1EBVA 2BOXA 2P28B 2W3IB 1U8CB 4XL1A 4RRYA 3TGFA 1MQ6L 1DVAL 1TPGA 2P16L 1XKAL 2WFTA 4X8UL 2J94B 3GISX 3LTGD 4LORA 2RA0L 3CS7L 4O02B 4NA9L 2XBYL 4LMFA 3CA7A 4RRWA 2P94L 2WPHE 2EI7B 1EPGA 3K9XA 3N8ZA 1PGEA 1RFNB 1NPEB 2WPIE 1LPGA 2ADXA 3S6XA 2OYEP 2Q1JB 2BOKL 1KLJL 4RRZA 2K2SB 2KL7A 3QCWA 1MOXC 2MHPA 2W86A 1HAEA 2WFXB 1Q4GA 2FZZL 1NFUB 2W2PE 2P26A 1MQ5L 3NTBA 1JBUL 1G2MB 1HCGB 1UZJA 3HS6A 5JVYA 1DX5I 2XC4L 2YGOA 4ZXYL 1HREA 2H9EC 2J4IB 1NQLB 3HS7A 1LPZA 2W2QE 4M11A 1U67A 3SOVA 2Y5GL 3ENSA 4NGAL 3MQEA 3IJEB 4ZH8B 2W26B 1GK5A 1IGZA 3NT1A 2FLRL 1XDTR 3KQEL 1TLEA 5IKQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HX2 A;  1NFX B;  1YO8 A;  4ZHA B;  2XBX L;  1F0R B;  2W3K B;  3QH0 A;  2F9B L;  5JB8 E;  1XKB A;  3HO4 A;  1ATA A;  1FF7 A;  2MGP A;  1EQH A;  1IP0 A;  4COX A;  1FSB A;  4FM5 A;  2XBV L;  4JYU L;  3Q7D A;  2JKH L;  3CFW A;  2BQ7 A;  4TGF A;  1HJ7 A;  1IQK L;  2WG3 C;  4BTU A;  4XBM A;  3KQB L;  1CQE A;  1IOX A;  3HO5 A;  1ATD A;  3GCW E;  2DDU A;  3EGF A;  3N8Y B;  1IQN L;  1ZAQ A;  3KQD L;  2P3F N;  2WPM E;  2VH0 B;  1Z6E L;  1YUF A;  4YT7 L;  2WYJ B;  4Z0K B;  1EMN A;  4BDX A;  4D90 A;  4BXW A;  3LN1 A;  2KV4 A;  4Y76 B;  5L2Z L;  2P95 L;  2D1J B;  4CUF A;  1IGX A;  2G00 L;  1CEJ A;  3LC5 B;  3ZYJ B;  2PR3 B;  1F0S B;  3FFG L;  1B9W A;  1CX2 A;  2K2T A;  1LMJ A;  3V64 C;  4Y6D B;  1C5M F;  2OYU P;  4CUD A;  1LQD A;  4BXS A;  5IKR A;  1CVW L;  2WPL E;  3ZYI B;  1IQM L;  1PXX A;  3SW2 A;  1JV2 B;  2WPK E;  1LPK A;  4RS0 A;  3FBY A;  1HRF A;  2TGF A;  3PGH A;  5EGM B;  2WYG B;  2UWO B;  2XC0 L;  3LAQ A;  2J34 B;  5L2Y L;  1W8B L;  5L30 L;  3U7U G;  1OB1 C;  1DDX A;  3N8Y A;  1J9C L;  1G2L B;  1EPH A;  4M10 A;  4ZAE B;  5KIR A;  3MDL A;  5I46 L;  4RRX A;  2VVC K;  1YUG A;  1NFY B;  2W2M E;  2H9E L;  3KRK A;  3KL6 B;  3LTF B;  1P0S L;  2CJI B;  2P3U A;  3QMO A;  2EI6 B;  1APQ A;  4MMZ B;  2J95 B;  2VWN L;  3N8X A;  1COU A;  4ZXX L;  1F7E A;  2FLB L;  1EGF A;  2WG4 B;  1EMO A;  4RUT A;  1QFK L;  4X8T L;  3F6U L;  3RR3 A;  3Q3K B;  4MMX B;  1CCV A;  2AYL A;  3P5B L;  1IQI L;  1W7X L;  2Y5F L;  1IQG L;  2VVU L;  1PTH A;  4JZF L;  1X7A L;  3TBD A;  2P3F L;  2B7D L;  1PRH A;  1KLO A;  4E1G A;  1WHF A;  4D0E A;  3SOQ A;  3V65 B;  3LN0 A;  1EQG A;  1UZQ A;  1XFE A;  1F7M A;  2FD6 A;  2WPJ E;  1HT5 A;  1FAK L;  1PFX L;  3KQC L;  1URK A;  2VWL L;  3IIT B;  1DQB A;  3M36 L;  1EZQ B;  2J38 B;  1KLI L;  3BT2 A;  3HO3 A;  3LC3 B;  1G1R A;  1WU1 B;  4AQT A;  4Y79 B;  3POY A;  5COX A;  2EI8 B;  3ELA L;  1HAF A;  4CSY A;  1EPI A;  1G1T A;  2VJ3 A;  2NPR A;  1IQF L;  4BDW A;  2Y7X B;  4JYV L;  1IQE L;  3LIW B;  5JBA E;  5CIS A;  5IKV A;  1HT8 A;  4PH9 A;  1NZI A;  5F19 A;  1L5G B;  4MMY B;  2Y38 A;  2FLG A;  1Z6C A;  3TK6 B;  5JBB E;  4D0F A;  2BO2 A;  2W2N E;  1CVU A;  3NTG A;  1IQJ L;  1IJQ A;  1IOE L;  2I9B A;  4BTT A;  1YUK B;  2UWL B;  1YGC L;  1M1X B;  2Y80 B;  1K36 A;  4C16 A;  1HZ8 A;  1G1Q A;  2PHB B;  3ZYG A;  3F1S B;  2BZ6 L;  1V3X B;  1IQL L;  4ISI L;  2BMG A;  2VVV L;  4YT6 L;  2RHP A;  4Y71 B;  1IQH L;  3HS5 A;  1L3Y A;  1FFM A;  2XC5 L;  3N8W B;  1IVO C;  4Z0L A;  2P93 L;  4Y7A B;  3NJP C;  3U73 A;  2I9A A;  1N1I A;  1O5D L;  2BQ6 A;  2J2U B;  2Y81 B;  2VWO L;  4ISH L;  3ASI A;  1NT0 A;  5CKN A;  2M74 A;  3TZI A;  1SZB A;  2YGP A;  4O1Z A;  5IKT A;  2P3T A;  4OTY A;  2UWP B;  3GCX E;  3DEM A;  5JW1 A;  1JL9 A;  5K0H B;  2RNL A;  4A7I A;  1N7D A;  4Y7B B;  3BPS E;  5JB9 E;  4Z6A L;  1FJS L;  2MGR A;  2BOU A;  3M37 L;  1DIY A;  2BQW A;  1UZP A;  2VWM K;  1AUT L;  4X8S L;  4CUE A;  3N8W A;  6COX A;  1BF9 A;  4BTI A;  4X8V L;  1WHE A;  1FE2 A;  2W2O E;  1APO A;  3R05 A;  1UZK A;  1ATB A;  2BOH A;  4JZE L;  2VH6 B;  2Y5H L;  2KB9 A;  1EAI C;  3KK6 A;  5FDQ A;  5KN5 C;  1I0U A;  3OLU A;  1ADX A;  1TOZ A;  1KSN B;  4YZU B;  4G1M B;  3HPT A;  3N8V A;  1KIG L;  2PUQ L;  5JVZ A;  5E8D A;  2XBW L;  2Y82 B;  1CCF A;  5CKQ A;  3SOB B;  3FCS B;  3OLT A;  3TH3 L;  3C9A C;  3BT1 A;  5CKM A;  1P9J A;  3H5C B;  1FAX L;  1NFW B;  3TK5 B;  1A3P A;  1ATE A;  2GD4 A;  4OTJ A;  2Y7Z B;  3KCG L;  1G1S A;  1EPJ A;  1K37 A;  5F1A A;  3CEN L;  4JZD L;  4XLW A;  5JBC E;  4NG9 L;  1EBV A;  2BOX A;  2P28 B;  2W3I B;  1U8C B;  4XL1 A;  4RRY A;  3TGF A;  1MQ6 L;  1DVA L;  1TPG A;  2P16 L;  1XKA L;  2WFT A;  4X8U L;  2J94 B;  3GIS X;  3LTG D;  4LOR A;  2RA0 L;  3CS7 L;  4O02 B;  4NA9 L;  2XBY L;  4LMF A;  3CA7 A;  4RRW A;  2P94 L;  2WPH E;  2EI7 B;  1EPG A;  3K9X A;  3N8Z A;  1PGE A;  1RFN B;  1NPE B;  2WPI E;  1LPG A;  2ADX A;  2OYE P;  2Q1J B;  2BOK L;  1KLJ L;  4RRZ A;  2K2S B;  2KL7 A;  3QCW A;  1MOX C;  2MHP A;  2W86 A;  1HAE A;  2WFX B;  1Q4G A;  2FZZ L;  1NFU B;  2W2P E;  2P26 A;  1MQ5 L;  3NTB A;  1JBU L;  1G2M B;  1HCG B;  1UZJ A;  3HS6 A;  5JVY A;  1DX5 I;  2XC4 L;  2YGO A;  4ZXY L;  1HRE A;  2J4I B;  1NQL B;  3HS7 A;  1LPZ A;  2W2Q E;  4M11 A;  1U67 A;  3SOV A;  2Y5G L;  3ENS A;  4NGA L;  3MQE A;  3IJE B;  4ZH8 B;  2W26 B;  1GK5 A;  1IGZ A;  3NT1 A;  2FLR L;  1XDT R;  3KQE L;  1TLE A;  5IKQ A; 
#chains in the Genus database with same CATH topology
 1HX2 A;  1NFX B;  1YO8 A;  2YGQ A;  2XBX L;  4ZHA B;  1F0R B;  2W3K B;  3QH0 A;  2F9B L;  4A94 C;  5JB8 E;  1XKB A;  3HO4 A;  1ATA A;  1FF7 A;  2MGP A;  1EQH A;  1IP0 A;  1V1H A;  2BT8 A;  4COX A;  1FSB A;  4FM5 A;  2XBV L;  4JYU L;  1QIU A;  3Q7D A;  1V1I A;  2JKH L;  3CFW A;  2BQ7 A;  4TGF A;  1HJ7 A;  1IQK L;  2WG3 C;  4BTU A;  4XBM A;  3KQB L;  1CQE A;  1IOX A;  3HO5 A;  1ATD A;  3GCW E;  2DDU A;  3EGF A;  3N8Y B;  1IQN L;  1ZAQ A;  3KQD L;  2P3F N;  2WPM E;  2VH0 B;  1Z6E L;  1YUF A;  4YT7 L;  2WYJ B;  4Z0K B;  1EMN A;  4BDX A;  4D90 A;  4BXW A;  3LN1 A;  2KV4 A;  4Y76 B;  5L2Z L;  2P95 L;  2D1J B;  4CUF A;  1IGX A;  2G00 L;  1CEJ A;  3LC5 B;  3ZYJ B;  2PR3 B;  1F0S B;  3FFG L;  1B9W A;  1CX2 A;  2K2T A;  1LMJ A;  3V64 C;  4Y6D B;  1C5M F;  2OYU P;  4CUD A;  1LQD A;  4BXS A;  5IKR A;  1CVW L;  2WPL E;  3ZYI B;  1IQM L;  1PXX A;  3SW2 A;  1JV2 B;  2BT7 A;  2WPK E;  1LPK A;  4RS0 A;  3FBY A;  1HRF A;  2TGF A;  3PGH A;  5EGM B;  2WYG B;  2UWO B;  2XC0 L;  3LAQ A;  2J34 B;  5L2Y L;  1W8B L;  5L30 L;  3U7U G;  1OB1 C;  1DDX A;  3N8Y A;  1J9C L;  1G2L B;  1EPH A;  4M10 A;  4ZAE B;  5KIR A;  3MDL A;  5I46 L;  4RRX A;  2VVC K;  1YUG A;  1NFY B;  2W2M E;  2H9E L;  3KRK A;  3KL6 B;  3LTF B;  1P0S L;  2CJI B;  2P3U A;  3QMO A;  2EI6 B;  1APQ A;  4MMZ B;  2J95 B;  2VWN L;  3N8X A;  1COU A;  4ZXX L;  1F7E A;  2FLB L;  1EGF A;  2WG4 B;  1EMO A;  4RUT A;  1QFK L;  1LMM A;  4X8T L;  3F6U L;  3RR3 A;  3Q3K B;  4MMX B;  2VRS A;  2AYL A;  1CCV A;  2KNI A;  3P5B L;  1IQI L;  1W7X L;  2Y5F L;  1IQG L;  2VVU L;  1PTH A;  4JZF L;  1X7A L;  3TBD A;  2P3F L;  2B7D L;  1PRH A;  1KLO A;  4E1G A;  1WHF A;  4D0E A;  3SOQ A;  3V65 B;  3LN0 A;  1EQG A;  1UZQ A;  1XFE A;  1F7M A;  2FD6 A;  2WPJ E;  1HT5 A;  1FAK L;  1PFX L;  3KQC L;  1URK A;  2VWL L;  3IIT B;  1DQB A;  3M36 L;  1EZQ B;  2J38 B;  1KLI L;  3BT2 A;  3HO3 A;  3LC3 B;  1G1R A;  1WU1 B;  4AQT A;  4Y79 B;  3POY A;  5COX A;  2EI8 B;  2BSF A;  3ELA L;  1HAF A;  4CSY A;  1EPI A;  1G1T A;  2VJ3 A;  2NPR A;  1IQF L;  4BDW A;  2Y7X B;  4JYV L;  2JJL A;  1IQE L;  3LIW B;  5JBA E;  5CIS A;  5IKV A;  1HT8 A;  4PH9 A;  1NZI A;  5F19 A;  1L5G B;  1KKE A;  2Y38 A;  2FLG A;  4MMY B;  1Z6C A;  3TK6 B;  4GU3 A;  5JBB E;  4D0F A;  2BO2 A;  2W2N E;  1CVU A;  3NTG A;  1IQJ L;  1IJQ A;  1IOE L;  2I9B A;  4BTT A;  1YUK B;  2UWL B;  1YGC L;  1M1X B;  2Y80 B;  1K36 A;  4C16 A;  1HZ8 A;  1G1Q A;  2PHB B;  3ZYG A;  3F1S B;  2BZ6 L;  1V3X B;  1IQL L;  4ISI L;  2BMG A;  2VVV L;  4YT6 L;  2RHP A;  4Y71 B;  1IQH L;  3HS5 A;  1L3Y A;  1FFM A;  2XC5 L;  3N8W B;  1IVO C;  4Z0L A;  2P93 L;  4Y7A B;  3NJP C;  3U73 A;  2I9A A;  1N1I A;  1O5D L;  2BQ6 A;  2J2U B;  2Y81 B;  2VWO L;  4ISH L;  3ASI A;  1NT0 A;  5CKN A;  1LK9 A;  2M74 A;  3TZI A;  1SZB A;  2YGP A;  4O1Z A;  2WZP P;  5IKT A;  2P3T A;  4OTY A;  2UWP B;  3GCX E;  3DEM A;  5JW1 A;  1JL9 A;  5K0H B;  2RNL A;  4A7I A;  1N7D A;  4Y7B B;  3BPS E;  5JB9 E;  4Z6A L;  1FJS L;  2MGR A;  2HOR A;  2BOU A;  3M37 L;  1DIY A;  2BQW A;  1UZP A;  2VWM K;  1AUT L;  4X8S L;  4CUE A;  3N8W A;  6COX A;  1BF9 A;  4BTI A;  4X8V L;  1WHE A;  1FE2 A;  2W2O E;  1APO A;  3R05 A;  1UZK A;  1ATB A;  2BOH A;  4JZE L;  2VH6 B;  2Y5H L;  2KB9 A;  1EAI C;  3KK6 A;  5FDQ A;  5KN5 C;  1I0U A;  3OLU A;  1ADX A;  1TOZ A;  1KSN B;  4YZU B;  4G1M B;  3HPT A;  3N8V A;  1KIG L;  2PUQ L;  5JVZ A;  5E8D A;  2XBW L;  2Y82 B;  1CCF A;  5CKQ A;  3SOB B;  3FCS B;  3OLT A;  3TH3 L;  3C9A C;  3BT1 A;  4GU4 A;  5CKM A;  1P9J A;  3H5C B;  1FAX L;  1NFW B;  3TK5 B;  1A3P A;  1ATE A;  2GD4 A;  4OTJ A;  2Y7Z B;  3KCG L;  1G1S A;  1EPJ A;  1K37 A;  5F1A A;  3CEN L;  4JZD L;  4XLW A;  5JBC E;  4NG9 L;  1EBV A;  2BOX A;  2P28 B;  2W3I B;  1U8C B;  4XL1 A;  4RRY A;  3TGF A;  1MQ6 L;  1DVA L;  1TPG A;  2P16 L;  1XKA L;  2WFT A;  4X8U L;  2J94 B;  3GIS X;  3LTG D;  4LOR A;  2RA0 L;  3CS7 L;  4O02 B;  4NA9 L;  2XBY L;  4LMF A;  3CA7 A;  4RRW A;  2P94 L;  2WPH E;  2EI7 B;  1EPG A;  3K9X A;  3N8Z A;  1PGE A;  1RFN B;  1NPE B;  2WPI E;  1LPG A;  2ADX A;  3S6X A;  2OYE P;  2Q1J B;  2BOK L;  1KLJ L;  4RRZ A;  2K2S B;  2KL7 A;  3QCW A;  1MOX C;  2MHP A;  2W86 A;  1HAE A;  2WFX B;  1Q4G A;  2FZZ L;  1NFU B;  2W2P E;  2P26 A;  1MQ5 L;  3NTB A;  1JBU L;  1G2M B;  1HCG B;  1UZJ A;  3HS6 A;  5JVY A;  1DX5 I;  2XC4 L;  2YGO A;  4ZXY L;  1HRE A;  2H9E C;  2J4I B;  1NQL B;  3HS7 A;  1LPZ A;  2W2Q E;  4M11 A;  1U67 A;  3SOV A;  2Y5G L;  3ENS A;  4NGA L;  3MQE A;  3IJE B;  4ZH8 B;  2HOX A;  2W26 B;  1GK5 A;  1IGZ A;  3NT1 A;  2FLR L;  1XDT R;  3KQE L;  1TLE A;  5IKQ A; 
#chains in the Genus database with same CATH homology
 1HX2 A;  1NFX B;  1YO8 A;  2YGQ A;  2XBX L;  4ZHA B;  1F0R B;  2W3K B;  3QH0 A;  2F9B L;  4A94 C;  5JB8 E;  1XKB A;  3HO4 A;  1ATA A;  1FF7 A;  2MGP A;  1EQH A;  1IP0 A;  4COX A;  1FSB A;  4FM5 A;  2XBV L;  4JYU L;  3Q7D A;  2JKH L;  3CFW A;  2BQ7 A;  4TGF A;  1HJ7 A;  1IQK L;  2WG3 C;  4BTU A;  4XBM A;  3KQB L;  1CQE A;  1IOX A;  3HO5 A;  1ATD A;  3GCW E;  2DDU A;  3EGF A;  3N8Y B;  1IQN L;  1ZAQ A;  3KQD L;  2P3F N;  2WPM E;  2VH0 B;  1Z6E L;  1YUF A;  4YT7 L;  2WYJ B;  4Z0K B;  1EMN A;  4BDX A;  4D90 A;  4BXW A;  3LN1 A;  2KV4 A;  4Y76 B;  5L2Z L;  2P95 L;  2D1J B;  4CUF A;  1IGX A;  2G00 L;  1CEJ A;  3LC5 B;  3ZYJ B;  2PR3 B;  1F0S B;  3FFG L;  1B9W A;  1CX2 A;  2K2T A;  1LMJ A;  3V64 C;  4Y6D B;  1C5M F;  2OYU P;  4CUD A;  1LQD A;  4BXS A;  5IKR A;  1CVW L;  2WPL E;  3ZYI B;  1IQM L;  1PXX A;  3SW2 A;  1JV2 B;  2WPK E;  1LPK A;  4RS0 A;  3FBY A;  1HRF A;  2TGF A;  3PGH A;  5EGM B;  2WYG B;  2UWO B;  2XC0 L;  3LAQ A;  2J34 B;  5L2Y L;  1W8B L;  5L30 L;  3U7U G;  1OB1 C;  1DDX A;  3N8Y A;  1J9C L;  1G2L B;  1EPH A;  4M10 A;  4ZAE B;  5KIR A;  3MDL A;  5I46 L;  4RRX A;  2VVC K;  1YUG A;  1NFY B;  2W2M E;  2H9E L;  3KRK A;  3KL6 B;  3LTF B;  1P0S L;  2CJI B;  2P3U A;  3QMO A;  2EI6 B;  1APQ A;  4MMZ B;  2J95 B;  2VWN L;  3N8X A;  1COU A;  4ZXX L;  1F7E A;  2FLB L;  1EGF A;  2WG4 B;  1EMO A;  4RUT A;  1QFK L;  1LMM A;  4X8T L;  3F6U L;  3RR3 A;  3Q3K B;  4MMX B;  1CCV A;  2AYL A;  2KNI A;  3P5B L;  1IQI L;  1W7X L;  2Y5F L;  1IQG L;  2VVU L;  1PTH A;  4JZF L;  1X7A L;  3TBD A;  2P3F L;  2B7D L;  1PRH A;  1KLO A;  4E1G A;  1WHF A;  4D0E A;  3SOQ A;  3V65 B;  3LN0 A;  1EQG A;  1UZQ A;  1XFE A;  1F7M A;  2FD6 A;  2WPJ E;  1HT5 A;  1FAK L;  1PFX L;  3KQC L;  1URK A;  2VWL L;  3IIT B;  1DQB A;  3M36 L;  1EZQ B;  2J38 B;  1KLI L;  3BT2 A;  3HO3 A;  3LC3 B;  1G1R A;  1WU1 B;  4AQT A;  4Y79 B;  3POY A;  5COX A;  2EI8 B;  3ELA L;  1HAF A;  4CSY A;  1EPI A;  1G1T A;  2VJ3 A;  2NPR A;  1IQF L;  4BDW A;  2Y7X B;  4JYV L;  1IQE L;  3LIW B;  5JBA E;  5CIS A;  5IKV A;  1HT8 A;  4PH9 A;  1NZI A;  5F19 A;  1L5G B;  4MMY B;  2Y38 A;  2FLG A;  1Z6C A;  3TK6 B;  5JBB E;  4D0F A;  2BO2 A;  2W2N E;  1CVU A;  3NTG A;  1IQJ L;  1IJQ A;  1IOE L;  2I9B A;  4BTT A;  1YUK B;  2UWL B;  1YGC L;  1M1X B;  2Y80 B;  1K36 A;  4C16 A;  1HZ8 A;  1G1Q A;  2PHB B;  3ZYG A;  3F1S B;  2BZ6 L;  1V3X B;  1IQL L;  4ISI L;  2BMG A;  2VVV L;  4YT6 L;  2RHP A;  4Y71 B;  1IQH L;  3HS5 A;  1L3Y A;  1FFM A;  2XC5 L;  3N8W B;  1IVO C;  4Z0L A;  2P93 L;  4Y7A B;  3NJP C;  3U73 A;  2I9A A;  1N1I A;  1O5D L;  2BQ6 A;  2J2U B;  2Y81 B;  2VWO L;  4ISH L;  3ASI A;  1NT0 A;  5CKN A;  2M74 A;  3TZI A;  1SZB A;  2YGP A;  4O1Z A;  2WZP P;  5IKT A;  2P3T A;  4OTY A;  2UWP B;  3GCX E;  3DEM A;  5JW1 A;  1JL9 A;  5K0H B;  2RNL A;  4A7I A;  1N7D A;  4Y7B B;  3BPS E;  5JB9 E;  4Z6A L;  1FJS L;  2MGR A;  2BOU A;  3M37 L;  1DIY A;  2BQW A;  1UZP A;  2VWM K;  1AUT L;  4X8S L;  4CUE A;  3N8W A;  6COX A;  1BF9 A;  4BTI A;  4X8V L;  1WHE A;  1FE2 A;  2W2O E;  1APO A;  3R05 A;  1UZK A;  1ATB A;  2BOH A;  4JZE L;  2VH6 B;  2Y5H L;  2KB9 A;  1EAI C;  3KK6 A;  5FDQ A;  5KN5 C;  1I0U A;  3OLU A;  1ADX A;  1TOZ A;  1KSN B;  4YZU B;  4G1M B;  3HPT A;  3N8V A;  1KIG L;  2PUQ L;  5JVZ A;  5E8D A;  2XBW L;  2Y82 B;  1CCF A;  5CKQ A;  3SOB B;  3FCS B;  3OLT A;  3TH3 L;  3C9A C;  3BT1 A;  5CKM A;  1P9J A;  3H5C B;  1FAX L;  1NFW B;  3TK5 B;  1A3P A;  1ATE A;  2GD4 A;  4OTJ A;  2Y7Z B;  3KCG L;  1G1S A;  1EPJ A;  1K37 A;  5F1A A;  3CEN L;  4JZD L;  4XLW A;  5JBC E;  4NG9 L;  1EBV A;  2BOX A;  2P28 B;  2W3I B;  1U8C B;  4XL1 A;  4RRY A;  3TGF A;  1MQ6 L;  1DVA L;  1TPG A;  2P16 L;  1XKA L;  2WFT A;  4X8U L;  2J94 B;  3GIS X;  3LTG D;  4LOR A;  2RA0 L;  3CS7 L;  4O02 B;  4NA9 L;  2XBY L;  4LMF A;  3CA7 A;  4RRW A;  2P94 L;  2WPH E;  2EI7 B;  1EPG A;  3K9X A;  3N8Z A;  1PGE A;  1RFN B;  1NPE B;  2WPI E;  1LPG A;  2ADX A;  3S6X A;  2OYE P;  2Q1J B;  2BOK L;  1KLJ L;  4RRZ A;  2K2S B;  2KL7 A;  3QCW A;  1MOX C;  2MHP A;  2W86 A;  1HAE A;  2WFX B;  1Q4G A;  2FZZ L;  1NFU B;  2W2P E;  2P26 A;  1MQ5 L;  3NTB A;  1JBU L;  1G2M B;  1HCG B;  1UZJ A;  3HS6 A;  5JVY A;  1DX5 I;  2XC4 L;  2YGO A;  4ZXY L;  1HRE A;  2H9E C;  2J4I B;  1NQL B;  3HS7 A;  1LPZ A;  2W2Q E;  4M11 A;  1U67 A;  3SOV A;  2Y5G L;  3ENS A;  4NGA L;  3MQE A;  3IJE B;  4ZH8 B;  2W26 B;  1GK5 A;  1IGZ A;  3NT1 A;  2FLR L;  1XDT R;  3KQE L;  1TLE A;  5IKQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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