4X8UL

Factor viia in complex with the inhibitor 5-chloro-1h-indole-2-carboxylic acid
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
55
structure length
55
Chain Sequence
ICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Novel P1 Groups for Coagulation Factor VIIa Inhibition Using Fragment-Based Screening.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Factor VIIa (Heavy Chain)
total genus 10
structure length 55
sequence length 55
ec nomenclature ec 3.4.21.21: Coagulation factor VIIa.
pdb deposition date 2014-12-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 4x8uL00
1ATBA 1W8BL 1Z6CA 4TGFA 1G2MB 1JV2B 1DVAL 4RRXA 2I9AA 1Z6EL 1B9WA 2BQ7A 5IKTA 4NG9L 5JVYA 1CVWL 5FDQA 4G1MB 4BXSA 4COXA 5L2ZL 3KQEL 1X7AL 2ADXA 1TPGA 2P93L 1NFWB 1CCVA 1YO8A 4CUEA 2D1JB 1AUTL 3C9AC 3ASIA 1EPIA 5EGMB 2BOKL 2WYJB 2PHBB 3QH0A 4RUTA 3QCWA 1IGZA 4NGAL 2VJ3A 3ZYIB 5CKNA 4Z6AL 4D90A 3POYA 5CISA 2Y38A 3NJPC 1XFEA 2Y5HL 3P5BL 2KL7A 1IQLL 4MMXB 2W3KB 1EZQB 1NFUB 5F19A 3ENSA 1KLJL 3KRKA 3QMOA 2WG3C 4AQTA 4MMZB 3GCXE 2W2PE 2J95B 4BTTA 2MHPA 1NT0A 4BDWA 2XBXL 1G2LB 4ZXXL 1BF9A 2FLRL 1DQBA 2YGOA 2WPHE 4ZXYL 5JBBE 5COXA 2J94B 1PFXL 2DDUA 1IQHL 2YGPA 4X8TL 1ZAQA 1U8CB 2Y7XB 1A3PA 3TZIA 3NT1A 4ISIL 1APQA 1J9CL 3TGFA 5KIRA 1P9JA 1L5GB 2P3UA 1FE2A 1NZIA 2VWLL 3N8WB 3BT2A 1WHFA 1FAKL 1CCFA 2G00L 1MQ5L 1DDXA 1ATDA 3N8YB 5JBAE 5F1AA 2P16L 3U73A 3HS5A 1KLOA 1KIGL 3ZYGA 4X8UL 1PRHA 3M36L 1FJSL 4Y76B 4JZDL 4RS0A 4X8VL 1HAEA 3HS6A 4M11A 2EI7B 4ZHAB 2FD6A 2RA0L 1ATAA 3K9XA 3TH3L 1IOEL 4O1ZA 1N7DA 1JBUL 2J38B 4BTUA 2VH6B 2WPME 1TOZA 3ZYJB 5IKRA 1WHEA 2XBVL 2W26B 4CUFA 1IQNL 1EMOA 4PH9A 1K37A 2BOHA 1IVOC 1PXXA 2XBWL 1YUGA 4JYUL 2P3TA 1HRFA 4YT6L 3KCGL 3TK6B 5L30L 1EPGA 3CFWA 4D0EA 3LAQA 4CSYA 2WYGB 1CVUA 2Y81B 1EGFA 5JBCE 2UWLB 1DX5I 3HO4A 2BO2A 2JKHL 2FLBL 3N8WA 2M74A 2W2OE 4NA9L 1YGCL 2RNLA 3OLUA 1IOXA 2VWMK 1W7XL 2W2NE 2VVUL 2VVCK 4CUDA 5JB8E 3KK6A 1CEJA 4OTYA 2Y5GL 3N8YA 3KQDL 2WFXB 1UZKA 4BTIA 1LPGA 1XKAL 3V65B 3KQBL 3Q7DA 5IKVA 5JW1A 4ISHL 4LORA 2BOXA 4JYVL 1NPEB 1DIYA 3V64C 4ZH8B 2KB9A 3U7UG 1O5DL 2VWOL 3PGHA 2BQ6A 2Y80B 1XKBA 3LTGD 3RR3A 2PUQL 2P94L 2WPLE 2Y82B 3N8XA 3GCWE 1CX2A 5IKQA 4LMFA 3FCSB 3GISX 3SW2A 1URKA 1C5MF 1G1SA 3NTBA 3BT1A 2NPRA 2VH0B 1Q4GA 1APOA 3BPSE 2EI6B 1UZPA 3CA7A 1IGXA 3CENL 1FF7A 5CKQA 1HAFA 4BDXA 2FZZL 1FAXL 5KN5C 2OYUP 1K36A 2RHPA 2J34B 3IITB 2WG4B 4X8SL 2W3IB 1NQLB 3HS7A 3LTFB 1YUFA 2BQWA 4YZUB 1KSNB 1F7MA 3H5CB 4JZEL 1P0SL 3LN0A 2J4IB 3EGFA 3FBYA 2Y7ZB 1LPKA 1IQJL 1I0UA 1IJQA 2J2UB 5I46L 3IJEB 1F7EA 4XBMA 1HJ7A 2P26A 1RFNB 4E1GA 3N8ZA 2EI8B 4RRYA 2P3FL 2XBYL 5K0HB 1PTHA 4RRWA 5JB9E 1IQML 2XC5L 1U67A 2MGPA 3LC3B 5L2YL 2CJIB 2MGRA 2TGFA 2K2SB 1GK5A 2P95L 3Q3KB 4RRZA 1F0SB 4ZAEB 1MQ6L 1NFYB 2BOUA 1FSBA 1V3XB 2KV4A 2XC0L 2FLGA 1L3YA 1JL9A 1MOXC 2UWOB 3N8VA 1G1QA 1FFMA 3TK5B 3MDLA 4M10A 1G1RA 4BXWA 3ELAL 4O02B 1IQIL 3MQEA 4JZFL 3HO5A 3KL6B 1LPZA 1CQEA 1IP0A 4A7IA 1LQDA 5JVZA 4Z0KB 3SOQA 4XLWA 2H9EL 4Y6DB 1KLIL 2BMGA 1IQKL 3HPTA 2K2TA 3TBDA 3DEMA 6COXA 2WFTA 1HT8A 3F6UL 3CS7L 1EMNA 1SZBA 1IQFL 2W86A 2W2QE 4Y7AB 3LIWB 3R05A 2B7DL 4Y7BB 4Z0LA 2GD4A 1WU1B 3F1SB 1EPJA 2Q1JB 3NTGA 1UZJA 1TLEA 2P3FN 1IQEL 4OTJA 1NFXB 5E8DA 2VWNL 2OYEP 4YT7L 2AYLA 2I9BA 1ATEA 1EAIC 1HX2A 1HREA 3SOVA 1HT5A 1G1TA 1HZ8A 4C16A 1COUA 1LMJA 3HO3A 1EQHA 2W2ME 2UWPB 3OLTA 3FFGL 4D0FA 1EPHA 4Y71B 2WPJE 2BZ6L 2WPIE 2PR3B 1UZQA 1EBVA 1F0RB 2XC4L 2P28B 1IQGL 3SOBB 1M1XB 1YUKB 4FM5A 1OB1C 5CKMA 1EQGA 4Y79B 1HCGB 2WPKE 1QFKL 2F9BL 3LN1A 3M37L 1PGEA 2Y5FL 1ADXA 3KQCL 2VVVL 4XL1A 1XDTR 1N1IA 3LC5B 4MMYB
chains in the Genus database with same CATH superfamily
1ATBA 1W8BL 1Z6CA 4TGFA 1G2MB 1JV2B 1DVAL 4RRXA 2I9AA 1Z6EL 1B9WA 2BQ7A 5IKTA 4NG9L 5JVYA 1CVWL 5FDQA 4G1MB 4BXSA 4COXA 5L2ZL 3KQEL 1X7AL 2ADXA 1TPGA 2P93L 1NFWB 4GU4A 1CCVA 1YO8A 4CUEA 2D1JB 1AUTL 3C9AC 3ASIA 1EPIA 5EGMB 2BOKL 2WYJB 2PHBB 3QH0A 4RUTA 3QCWA 1IGZA 4NGAL 2VJ3A 3ZYIB 5CKNA 2HORA 4D90A 4Z6AL 3POYA 4A94C 5CISA 2Y38A 3NJPC 1XFEA 2Y5HL 3P5BL 2KL7A 1IQLL 4MMXB 2W3KB 1EZQB 1NFUB 5F19A 3ENSA 1KLJL 3KRKA 3QMOA 2WG3C 4AQTA 4MMZB 3GCXE 2W2PE 2J95B 4BTTA 2MHPA 1NT0A 4BDWA 2XBXL 1G2LB 4ZXXL 1BF9A 2FLRL 1DQBA 2YGOA 2WPHE 4ZXYL 5JBBE 5COXA 2J94B 1PFXL 2DDUA 1IQHL 2YGPA 4X8TL 1ZAQA 1U8CB 2Y7XB 1LK9A 1A3PA 3TZIA 3NT1A 4ISIL 1APQA 1J9CL 3TGFA 5KIRA 1P9JA 1L5GB 2P3UA 1FE2A 1NZIA 2VWLL 3N8WB 3BT2A 1WHFA 1FAKL 1CCFA 2G00L 1MQ5L 1DDXA 1ATDA 2BSFA 3N8YB 5JBAE 5F1AA 2P16L 3U73A 3HS5A 1KLOA 1KIGL 3ZYGA 4X8UL 1PRHA 3M36L 1FJSL 4Y76B 4JZDL 4RS0A 4X8VL 1HAEA 3HS6A 4M11A 1LMMA 2EI7B 4ZHAB 2FD6A 2RA0L 1ATAA 3K9XA 3TH3L 1IOEL 4O1ZA 1N7DA 1JBUL 2J38B 4BTUA 2VH6B 2WPME 1TOZA 3ZYJB 5IKRA 1WHEA 2XBVL 2W26B 1V1HA 4CUFA 1IQNL 1EMOA 4PH9A 1K37A 2BOHA 1IVOC 1PXXA 2XBWL 1YUGA 2H9EC 4JYUL 2P3TA 1HRFA 4YT6L 3KCGL 3TK6B 5L30L 1EPGA 3CFWA 4D0EA 3LAQA 2JJLA 4CSYA 2WYGB 1CVUA 2Y81B 1EGFA 5JBCE 2UWLB 1DX5I 3HO4A 2BO2A 2JKHL 2FLBL 3N8WA 2M74A 2W2OE 4NA9L 1YGCL 2RNLA 3OLUA 1IOXA 2VWMK 1W7XL 2W2NE 2VVUL 2VVCK 4CUDA 5JB8E 3KK6A 1CEJA 4OTYA 2Y5GL 3N8YA 1V1IA 3KQDL 2WFXB 1UZKA 4BTIA 1LPGA 1XKAL 3V65B 3KQBL 1QIUA 3Q7DA 5IKVA 5JW1A 4ISHL 4LORA 2BOXA 4JYVL 1NPEB 1DIYA 2BT7A 3V64C 4ZH8B 2KB9A 3U7UG 1O5DL 2VWOL 3PGHA 2BQ6A 2Y80B 1XKBA 3LTGD 3RR3A 2PUQL 2P94L 2WPLE 2Y82B 3N8XA 3GCWE 1CX2A 5IKQA 4LMFA 3FCSB 3GISX 3SW2A 1URKA 1C5MF 1G1SA 3NTBA 3BT1A 2NPRA 2VH0B 1Q4GA 1APOA 3BPSE 2EI6B 1UZPA 3CA7A 1IGXA 3CENL 1FF7A 5CKQA 1HAFA 4BDXA 2FZZL 1FAXL 5KN5C 2OYUP 1K36A 2RHPA 2J34B 3IITB 2WG4B 4X8SL 2W3IB 1NQLB 3HS7A 3LTFB 1YUFA 2BQWA 4YZUB 1KSNB 1F7MA 3H5CB 4JZEL 1P0SL 3LN0A 2J4IB 3EGFA 3FBYA 2Y7ZB 1LPKA 1IQJL 1I0UA 1IJQA 2J2UB 5I46L 3IJEB 1F7EA 4XBMA 1HJ7A 2P26A 1RFNB 4E1GA 3N8ZA 2EI8B 4RRYA 2P3FL 2XBYL 5K0HB 1PTHA 4RRWA 5JB9E 1IQML 2XC5L 1U67A 3S6XA 2MGPA 3LC3B 5L2YL 2CJIB 2MGRA 2TGFA 2K2SB 1GK5A 2P95L 3Q3KB 4RRZA 1F0SB 4ZAEB 1MQ6L 1NFYB 2BOUA 1FSBA 1V3XB 2KV4A 2XC0L 2FLGA 1L3YA 1JL9A 1MOXC 2UWOB 3N8VA 1G1QA 1FFMA 3TK5B 3MDLA 4M10A 1G1RA 4BXWA 3ELAL 4O02B 1IQIL 1KKEA 3MQEA 4JZFL 3HO5A 3KL6B 1LPZA 1CQEA 2YGQA 1IP0A 4A7IA 1LQDA 5JVZA 2BT8A 4Z0KB 3SOQA 2HOXA 4XLWA 2H9EL 4Y6DB 1KLIL 2BMGA 1IQKL 3HPTA 2K2TA 3TBDA 3DEMA 6COXA 2WFTA 1HT8A 3F6UL 3CS7L 1EMNA 1SZBA 1IQFL 2W86A 2W2QE 4Y7AB 3LIWB 3R05A 2B7DL 4GU3A 4Y7BB 2GD4A 1WU1B 3F1SB 4Z0LA 1EPJA 2Q1JB 3NTGA 1UZJA 1TLEA 2P3FN 1IQEL 4OTJA 1NFXB 5E8DA 2VWNL 2OYEP 4YT7L 2AYLA 2I9BA 1ATEA 1EAIC 2VRSA 1HX2A 1HREA 3SOVA 1HT5A 1G1TA 1HZ8A 4C16A 1COUA 1LMJA 3HO3A 1EQHA 2W2ME 2UWPB 3OLTA 3FFGL 4D0FA 1EPHA 4Y71B 2WPJE 2BZ6L 2WPIE 2WZPP 2PR3B 1UZQA 1EBVA 1F0RB 2XC4L 2P28B 1IQGL 3SOBB 1M1XB 1YUKB 4FM5A 1OB1C 5CKMA 1EQGA 4Y79B 1HCGB 2WPKE 1QFKL 2F9BL 3LN1A 3M37L 1PGEA 2Y5FL 1ADXA 3KQCL 2VVVL 4XL1A 1XDTR 2KNIA 1N1IA 3LC5B 4MMYB
chains in the Genus database with same CATH topology
1ATBA 1W8BL 1Z6CA 4TGFA 1G2MB 1JV2B 1DVAL 4RRXA 2I9AA 1Z6EL 1B9WA 2BQ7A 5IKTA 4NG9L 5JVYA 1CVWL 5FDQA 4G1MB 4BXSA 4COXA 5L2ZL 3KQEL 1X7AL 2ADXA 1TPGA 2P93L 1NFWB 1CCVA 1YO8A 4CUEA 2D1JB 1AUTL 3C9AC 3ASIA 1EPIA 5EGMB 2BOKL 2WYJB 2PHBB 3QH0A 4RUTA 3QCWA 1IGZA 4NGAL 2VJ3A 3ZYIB 5CKNA 4Z6AL 4D90A 3POYA 4A94C 5CISA 2Y38A 3NJPC 1XFEA 2Y5HL 3P5BL 2KL7A 1IQLL 4MMXB 2W3KB 1EZQB 1NFUB 5F19A 3ENSA 1KLJL 3KRKA 3QMOA 2WG3C 4AQTA 4MMZB 3GCXE 2W2PE 2J95B 4BTTA 2MHPA 1NT0A 4BDWA 2XBXL 1G2LB 4ZXXL 1BF9A 2FLRL 1DQBA 2YGOA 2WPHE 4ZXYL 5JBBE 5COXA 2J94B 1PFXL 2DDUA 1IQHL 2YGPA 4X8TL 1ZAQA 1U8CB 2Y7XB 1A3PA 3TZIA 3NT1A 4ISIL 1APQA 1J9CL 3TGFA 5KIRA 1P9JA 1L5GB 2P3UA 1FE2A 1NZIA 2VWLL 3N8WB 3BT2A 1WHFA 1FAKL 1CCFA 2G00L 1MQ5L 1DDXA 1ATDA 3N8YB 5JBAE 5F1AA 2P16L 3U73A 3HS5A 1KLOA 1KIGL 3ZYGA 4X8UL 1PRHA 3M36L 1FJSL 4Y76B 4JZDL 4RS0A 4X8VL 1HAEA 3HS6A 4M11A 1LMMA 2EI7B 4ZHAB 2FD6A 2RA0L 1ATAA 3K9XA 3TH3L 1IOEL 4O1ZA 1N7DA 1JBUL 2J38B 4BTUA 2VH6B 2WPME 1TOZA 3ZYJB 5IKRA 1WHEA 2XBVL 2W26B 4CUFA 1IQNL 1EMOA 4PH9A 1K37A 2BOHA 1IVOC 1PXXA 2XBWL 1YUGA 2H9EC 4JYUL 2P3TA 1HRFA 4YT6L 3KCGL 3TK6B 5L30L 1EPGA 3CFWA 4D0EA 3LAQA 4CSYA 2WYGB 1CVUA 2Y81B 1EGFA 5JBCE 2UWLB 1DX5I 3HO4A 2BO2A 2JKHL 2FLBL 3N8WA 2M74A 2W2OE 4NA9L 1YGCL 2RNLA 3OLUA 1IOXA 2VWMK 1W7XL 2W2NE 2VVUL 2VVCK 4CUDA 5JB8E 3KK6A 1CEJA 4OTYA 2Y5GL 3N8YA 3KQDL 2WFXB 1UZKA 4BTIA 1LPGA 1XKAL 3V65B 3KQBL 3Q7DA 5IKVA 5JW1A 4ISHL 4LORA 2BOXA 4JYVL 1NPEB 1DIYA 3V64C 4ZH8B 2KB9A 3U7UG 1O5DL 2VWOL 3PGHA 2BQ6A 2Y80B 1XKBA 3LTGD 3RR3A 2PUQL 2P94L 2WPLE 2Y82B 3N8XA 3GCWE 1CX2A 5IKQA 4LMFA 3FCSB 3GISX 3SW2A 1URKA 1C5MF 1G1SA 3NTBA 3BT1A 2NPRA 2VH0B 1Q4GA 1APOA 3BPSE 2EI6B 1UZPA 3CA7A 1IGXA 3CENL 1FF7A 5CKQA 1HAFA 4BDXA 2FZZL 1FAXL 5KN5C 2OYUP 1K36A 2RHPA 2J34B 3IITB 2WG4B 4X8SL 2W3IB 1NQLB 3HS7A 3LTFB 1YUFA 2BQWA 4YZUB 1KSNB 1F7MA 3H5CB 4JZEL 1P0SL 3LN0A 2J4IB 3EGFA 3FBYA 2Y7ZB 1LPKA 1IQJL 1I0UA 1IJQA 2J2UB 5I46L 3IJEB 1F7EA 4XBMA 1HJ7A 2P26A 1RFNB 4E1GA 3N8ZA 2EI8B 4RRYA 2P3FL 2XBYL 5K0HB 1PTHA 4RRWA 5JB9E 1IQML 2XC5L 1U67A 3S6XA 2MGPA 3LC3B 5L2YL 2CJIB 2MGRA 2TGFA 2K2SB 1GK5A 2P95L 3Q3KB 4RRZA 1F0SB 4ZAEB 1MQ6L 1NFYB 2BOUA 1FSBA 1V3XB 2KV4A 2XC0L 2FLGA 1L3YA 1JL9A 1MOXC 2UWOB 3N8VA 1G1QA 1FFMA 3TK5B 3MDLA 4M10A 1G1RA 4BXWA 3ELAL 4O02B 1IQIL 3MQEA 4JZFL 3HO5A 3KL6B 1LPZA 1CQEA 2YGQA 1IP0A 4A7IA 1LQDA 5JVZA 4Z0KB 3SOQA 4XLWA 2H9EL 4Y6DB 1KLIL 2BMGA 1IQKL 3HPTA 2K2TA 3TBDA 3DEMA 6COXA 2WFTA 1HT8A 3F6UL 3CS7L 1EMNA 1SZBA 1IQFL 2W86A 2W2QE 4Y7AB 3LIWB 3R05A 2B7DL 4Y7BB 4Z0LA 2GD4A 1WU1B 3F1SB 1EPJA 2Q1JB 3NTGA 1UZJA 1TLEA 2P3FN 1IQEL 4OTJA 1NFXB 5E8DA 2VWNL 2OYEP 4YT7L 2AYLA 2I9BA 1ATEA 1EAIC 1HX2A 1HREA 3SOVA 1HT5A 1G1TA 1HZ8A 4C16A 1COUA 1LMJA 3HO3A 1EQHA 2W2ME 2UWPB 3OLTA 3FFGL 4D0FA 1EPHA 4Y71B 2WPJE 2BZ6L 2WPIE 2WZPP 2PR3B 1UZQA 1EBVA 1F0RB 2XC4L 2P28B 1IQGL 3SOBB 1M1XB 1YUKB 4FM5A 1OB1C 5CKMA 1EQGA 4Y79B 1HCGB 2WPKE 1QFKL 2F9BL 3LN1A 3M37L 1PGEA 2Y5FL 1ADXA 3KQCL 2VVVL 4XL1A 1XDTR 2KNIA 1N1IA 3LC5B 4MMYB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ATB A;  1W8B L;  1Z6C A;  4TGF A;  1G2M B;  1JV2 B;  1DVA L;  4RRX A;  2I9A A;  1Z6E L;  1B9W A;  2BQ7 A;  5IKT A;  4NG9 L;  5JVY A;  1CVW L;  5FDQ A;  4G1M B;  4BXS A;  4COX A;  5L2Z L;  3KQE L;  1X7A L;  2ADX A;  1TPG A;  2P93 L;  1NFW B;  1CCV A;  1YO8 A;  4CUE A;  2D1J B;  1AUT L;  3C9A C;  3ASI A;  1EPI A;  5EGM B;  2BOK L;  2WYJ B;  2PHB B;  3QH0 A;  4RUT A;  3QCW A;  1IGZ A;  4NGA L;  2VJ3 A;  3ZYI B;  5CKN A;  4Z6A L;  4D90 A;  3POY A;  5CIS A;  2Y38 A;  3NJP C;  1XFE A;  2Y5H L;  3P5B L;  2KL7 A;  1IQL L;  4MMX B;  2W3K B;  1EZQ B;  1NFU B;  5F19 A;  3ENS A;  1KLJ L;  3KRK A;  3QMO A;  2WG3 C;  4AQT A;  4MMZ B;  3GCX E;  2W2P E;  2J95 B;  4BTT A;  2MHP A;  1NT0 A;  4BDW A;  2XBX L;  1G2L B;  4ZXX L;  1BF9 A;  2FLR L;  1DQB A;  2YGO A;  2WPH E;  4ZXY L;  5JBB E;  5COX A;  2J94 B;  1PFX L;  2DDU A;  1IQH L;  2YGP A;  4X8T L;  1ZAQ A;  1U8C B;  2Y7X B;  1A3P A;  3TZI A;  3NT1 A;  4ISI L;  1APQ A;  1J9C L;  3TGF A;  5KIR A;  1P9J A;  1L5G B;  2P3U A;  1FE2 A;  1NZI A;  2VWL L;  3N8W B;  3BT2 A;  1WHF A;  1FAK L;  1CCF A;  2G00 L;  1MQ5 L;  1DDX A;  1ATD A;  3N8Y B;  5JBA E;  5F1A A;  2P16 L;  3U73 A;  3HS5 A;  1KLO A;  1KIG L;  3ZYG A;  4X8U L;  1PRH A;  3M36 L;  1FJS L;  4Y76 B;  4JZD L;  4RS0 A;  4X8V L;  1HAE A;  3HS6 A;  4M11 A;  2EI7 B;  4ZHA B;  2FD6 A;  2RA0 L;  1ATA A;  3K9X A;  3TH3 L;  1IOE L;  4O1Z A;  1N7D A;  1JBU L;  2J38 B;  4BTU A;  2VH6 B;  2WPM E;  1TOZ A;  3ZYJ B;  5IKR A;  1WHE A;  2XBV L;  2W26 B;  4CUF A;  1IQN L;  1EMO A;  4PH9 A;  1K37 A;  2BOH A;  1IVO C;  1PXX A;  2XBW L;  1YUG A;  4JYU L;  2P3T A;  1HRF A;  4YT6 L;  3KCG L;  3TK6 B;  5L30 L;  1EPG A;  3CFW A;  4D0E A;  3LAQ A;  4CSY A;  2WYG B;  1CVU A;  2Y81 B;  1EGF A;  5JBC E;  2UWL B;  1DX5 I;  3HO4 A;  2BO2 A;  2JKH L;  2FLB L;  3N8W A;  2M74 A;  2W2O E;  4NA9 L;  1YGC L;  2RNL A;  3OLU A;  1IOX A;  2VWM K;  1W7X L;  2W2N E;  2VVU L;  2VVC K;  4CUD A;  5JB8 E;  3KK6 A;  1CEJ A;  4OTY A;  2Y5G L;  3N8Y A;  3KQD L;  2WFX B;  1UZK A;  4BTI A;  1LPG A;  1XKA L;  3V65 B;  3KQB L;  3Q7D A;  5IKV A;  5JW1 A;  4ISH L;  4LOR A;  2BOX A;  4JYV L;  1NPE B;  1DIY A;  3V64 C;  4ZH8 B;  2KB9 A;  3U7U G;  1O5D L;  2VWO L;  3PGH A;  2BQ6 A;  2Y80 B;  1XKB A;  3LTG D;  3RR3 A;  2PUQ L;  2P94 L;  2WPL E;  2Y82 B;  3N8X A;  3GCW E;  1CX2 A;  5IKQ A;  4LMF A;  3FCS B;  3GIS X;  3SW2 A;  1URK A;  1C5M F;  1G1S A;  3NTB A;  3BT1 A;  2NPR A;  2VH0 B;  1Q4G A;  1APO A;  3BPS E;  2EI6 B;  1UZP A;  3CA7 A;  1IGX A;  3CEN L;  1FF7 A;  5CKQ A;  1HAF A;  4BDX A;  2FZZ L;  1FAX L;  5KN5 C;  2OYU P;  1K36 A;  2RHP A;  2J34 B;  3IIT B;  2WG4 B;  4X8S L;  2W3I B;  1NQL B;  3HS7 A;  3LTF B;  1YUF A;  2BQW A;  4YZU B;  1KSN B;  1F7M A;  3H5C B;  4JZE L;  1P0S L;  3LN0 A;  2J4I B;  3EGF A;  3FBY A;  2Y7Z B;  1LPK A;  1IQJ L;  1I0U A;  1IJQ A;  2J2U B;  5I46 L;  3IJE B;  1F7E A;  4XBM A;  1HJ7 A;  2P26 A;  1RFN B;  4E1G A;  3N8Z A;  2EI8 B;  4RRY A;  2P3F L;  2XBY L;  5K0H B;  1PTH A;  4RRW A;  5JB9 E;  1IQM L;  2XC5 L;  1U67 A;  2MGP A;  3LC3 B;  5L2Y L;  2CJI B;  2MGR A;  2TGF A;  2K2S B;  1GK5 A;  2P95 L;  3Q3K B;  4RRZ A;  1F0S B;  4ZAE B;  1MQ6 L;  1NFY B;  2BOU A;  1FSB A;  1V3X B;  2KV4 A;  2XC0 L;  2FLG A;  1L3Y A;  1JL9 A;  1MOX C;  2UWO B;  3N8V A;  1G1Q A;  1FFM A;  3TK5 B;  3MDL A;  4M10 A;  1G1R A;  4BXW A;  3ELA L;  4O02 B;  1IQI L;  3MQE A;  4JZF L;  3HO5 A;  3KL6 B;  1LPZ A;  1CQE A;  1IP0 A;  4A7I A;  1LQD A;  5JVZ A;  4Z0K B;  3SOQ A;  4XLW A;  2H9E L;  4Y6D B;  1KLI L;  2BMG A;  1IQK L;  3HPT A;  2K2T A;  3TBD A;  3DEM A;  6COX A;  2WFT A;  1HT8 A;  3F6U L;  3CS7 L;  1EMN A;  1SZB A;  1IQF L;  2W86 A;  2W2Q E;  4Y7A B;  3LIW B;  3R05 A;  2B7D L;  4Y7B B;  4Z0L A;  2GD4 A;  1WU1 B;  3F1S B;  1EPJ A;  2Q1J B;  3NTG A;  1UZJ A;  1TLE A;  2P3F N;  1IQE L;  4OTJ A;  1NFX B;  5E8D A;  2VWN L;  2OYE P;  4YT7 L;  2AYL A;  2I9B A;  1ATE A;  1EAI C;  1HX2 A;  1HRE A;  3SOV A;  1HT5 A;  1G1T A;  1HZ8 A;  4C16 A;  1COU A;  1LMJ A;  3HO3 A;  1EQH A;  2W2M E;  2UWP B;  3OLT A;  3FFG L;  4D0F A;  1EPH A;  4Y71 B;  2WPJ E;  2BZ6 L;  2WPI E;  2PR3 B;  1UZQ A;  1EBV A;  1F0R B;  2XC4 L;  2P28 B;  1IQG L;  3SOB B;  1M1X B;  1YUK B;  4FM5 A;  1OB1 C;  5CKM A;  1EQG A;  4Y79 B;  1HCG B;  2WPK E;  1QFK L;  2F9B L;  3LN1 A;  3M37 L;  1PGE A;  2Y5F L;  1ADX A;  3KQC L;  2VVV L;  4XL1 A;  1XDT R;  1N1I A;  3LC5 B;  4MMY B; 
#chains in the Genus database with same CATH topology
 1ATB A;  1W8B L;  1Z6C A;  4TGF A;  1G2M B;  1JV2 B;  1DVA L;  4RRX A;  2I9A A;  1Z6E L;  1B9W A;  2BQ7 A;  5IKT A;  4NG9 L;  5JVY A;  1CVW L;  5FDQ A;  4G1M B;  4BXS A;  4COX A;  5L2Z L;  3KQE L;  1X7A L;  2ADX A;  1TPG A;  2P93 L;  1NFW B;  4GU4 A;  1CCV A;  1YO8 A;  4CUE A;  2D1J B;  1AUT L;  3C9A C;  3ASI A;  1EPI A;  5EGM B;  2BOK L;  2WYJ B;  2PHB B;  3QH0 A;  4RUT A;  3QCW A;  1IGZ A;  4NGA L;  2VJ3 A;  3ZYI B;  5CKN A;  2HOR A;  4D90 A;  4Z6A L;  3POY A;  4A94 C;  5CIS A;  2Y38 A;  3NJP C;  1XFE A;  2Y5H L;  3P5B L;  2KL7 A;  1IQL L;  4MMX B;  2W3K B;  1EZQ B;  1NFU B;  5F19 A;  3ENS A;  1KLJ L;  3KRK A;  3QMO A;  2WG3 C;  4AQT A;  4MMZ B;  3GCX E;  2W2P E;  2J95 B;  4BTT A;  2MHP A;  1NT0 A;  4BDW A;  2XBX L;  1G2L B;  4ZXX L;  1BF9 A;  2FLR L;  1DQB A;  2YGO A;  2WPH E;  4ZXY L;  5JBB E;  5COX A;  2J94 B;  1PFX L;  2DDU A;  1IQH L;  2YGP A;  4X8T L;  1ZAQ A;  1U8C B;  2Y7X B;  1LK9 A;  1A3P A;  3TZI A;  3NT1 A;  4ISI L;  1APQ A;  1J9C L;  3TGF A;  5KIR A;  1P9J A;  1L5G B;  2P3U A;  1FE2 A;  1NZI A;  2VWL L;  3N8W B;  3BT2 A;  1WHF A;  1FAK L;  1CCF A;  2G00 L;  1MQ5 L;  1DDX A;  1ATD A;  2BSF A;  3N8Y B;  5JBA E;  5F1A A;  2P16 L;  3U73 A;  3HS5 A;  1KLO A;  1KIG L;  3ZYG A;  4X8U L;  1PRH A;  3M36 L;  1FJS L;  4Y76 B;  4JZD L;  4RS0 A;  4X8V L;  1HAE A;  3HS6 A;  4M11 A;  1LMM A;  2EI7 B;  4ZHA B;  2FD6 A;  2RA0 L;  1ATA A;  3K9X A;  3TH3 L;  1IOE L;  4O1Z A;  1N7D A;  1JBU L;  2J38 B;  4BTU A;  2VH6 B;  2WPM E;  1TOZ A;  3ZYJ B;  5IKR A;  1WHE A;  2XBV L;  2W26 B;  1V1H A;  4CUF A;  1IQN L;  1EMO A;  4PH9 A;  1K37 A;  2BOH A;  1IVO C;  1PXX A;  2XBW L;  1YUG A;  2H9E C;  4JYU L;  2P3T A;  1HRF A;  4YT6 L;  3KCG L;  3TK6 B;  5L30 L;  1EPG A;  3CFW A;  4D0E A;  3LAQ A;  2JJL A;  4CSY A;  2WYG B;  1CVU A;  2Y81 B;  1EGF A;  5JBC E;  2UWL B;  1DX5 I;  3HO4 A;  2BO2 A;  2JKH L;  2FLB L;  3N8W A;  2M74 A;  2W2O E;  4NA9 L;  1YGC L;  2RNL A;  3OLU A;  1IOX A;  2VWM K;  1W7X L;  2W2N E;  2VVU L;  2VVC K;  4CUD A;  5JB8 E;  3KK6 A;  1CEJ A;  4OTY A;  2Y5G L;  3N8Y A;  1V1I A;  3KQD L;  2WFX B;  1UZK A;  4BTI A;  1LPG A;  1XKA L;  3V65 B;  3KQB L;  1QIU A;  3Q7D A;  5IKV A;  5JW1 A;  4ISH L;  4LOR A;  2BOX A;  4JYV L;  1NPE B;  1DIY A;  2BT7 A;  3V64 C;  4ZH8 B;  2KB9 A;  3U7U G;  1O5D L;  2VWO L;  3PGH A;  2BQ6 A;  2Y80 B;  1XKB A;  3LTG D;  3RR3 A;  2PUQ L;  2P94 L;  2WPL E;  2Y82 B;  3N8X A;  3GCW E;  1CX2 A;  5IKQ A;  4LMF A;  3FCS B;  3GIS X;  3SW2 A;  1URK A;  1C5M F;  1G1S A;  3NTB A;  3BT1 A;  2NPR A;  2VH0 B;  1Q4G A;  1APO A;  3BPS E;  2EI6 B;  1UZP A;  3CA7 A;  1IGX A;  3CEN L;  1FF7 A;  5CKQ A;  1HAF A;  4BDX A;  2FZZ L;  1FAX L;  5KN5 C;  2OYU P;  1K36 A;  2RHP A;  2J34 B;  3IIT B;  2WG4 B;  4X8S L;  2W3I B;  1NQL B;  3HS7 A;  3LTF B;  1YUF A;  2BQW A;  4YZU B;  1KSN B;  1F7M A;  3H5C B;  4JZE L;  1P0S L;  3LN0 A;  2J4I B;  3EGF A;  3FBY A;  2Y7Z B;  1LPK A;  1IQJ L;  1I0U A;  1IJQ A;  2J2U B;  5I46 L;  3IJE B;  1F7E A;  4XBM A;  1HJ7 A;  2P26 A;  1RFN B;  4E1G A;  3N8Z A;  2EI8 B;  4RRY A;  2P3F L;  2XBY L;  5K0H B;  1PTH A;  4RRW A;  5JB9 E;  1IQM L;  2XC5 L;  1U67 A;  3S6X A;  2MGP A;  3LC3 B;  5L2Y L;  2CJI B;  2MGR A;  2TGF A;  2K2S B;  1GK5 A;  2P95 L;  3Q3K B;  4RRZ A;  1F0S B;  4ZAE B;  1MQ6 L;  1NFY B;  2BOU A;  1FSB A;  1V3X B;  2KV4 A;  2XC0 L;  2FLG A;  1L3Y A;  1JL9 A;  1MOX C;  2UWO B;  3N8V A;  1G1Q A;  1FFM A;  3TK5 B;  3MDL A;  4M10 A;  1G1R A;  4BXW A;  3ELA L;  4O02 B;  1IQI L;  1KKE A;  3MQE A;  4JZF L;  3HO5 A;  3KL6 B;  1LPZ A;  1CQE A;  2YGQ A;  1IP0 A;  4A7I A;  1LQD A;  5JVZ A;  2BT8 A;  4Z0K B;  3SOQ A;  2HOX A;  4XLW A;  2H9E L;  4Y6D B;  1KLI L;  2BMG A;  1IQK L;  3HPT A;  2K2T A;  3TBD A;  3DEM A;  6COX A;  2WFT A;  1HT8 A;  3F6U L;  3CS7 L;  1EMN A;  1SZB A;  1IQF L;  2W86 A;  2W2Q E;  4Y7A B;  3LIW B;  3R05 A;  2B7D L;  4GU3 A;  4Y7B B;  2GD4 A;  1WU1 B;  3F1S B;  4Z0L A;  1EPJ A;  2Q1J B;  3NTG A;  1UZJ A;  1TLE A;  2P3F N;  1IQE L;  4OTJ A;  1NFX B;  5E8D A;  2VWN L;  2OYE P;  4YT7 L;  2AYL A;  2I9B A;  1ATE A;  1EAI C;  2VRS A;  1HX2 A;  1HRE A;  3SOV A;  1HT5 A;  1G1T A;  1HZ8 A;  4C16 A;  1COU A;  1LMJ A;  3HO3 A;  1EQH A;  2W2M E;  2UWP B;  3OLT A;  3FFG L;  4D0F A;  1EPH A;  4Y71 B;  2WPJ E;  2BZ6 L;  2WPI E;  2WZP P;  2PR3 B;  1UZQ A;  1EBV A;  1F0R B;  2XC4 L;  2P28 B;  1IQG L;  3SOB B;  1M1X B;  1YUK B;  4FM5 A;  1OB1 C;  5CKM A;  1EQG A;  4Y79 B;  1HCG B;  2WPK E;  1QFK L;  2F9B L;  3LN1 A;  3M37 L;  1PGE A;  2Y5F L;  1ADX A;  3KQC L;  2VVV L;  4XL1 A;  1XDT R;  2KNI A;  1N1I A;  3LC5 B;  4MMY B; 
#chains in the Genus database with same CATH homology
 1ATB A;  1W8B L;  1Z6C A;  4TGF A;  1G2M B;  1JV2 B;  1DVA L;  4RRX A;  2I9A A;  1Z6E L;  1B9W A;  2BQ7 A;  5IKT A;  4NG9 L;  5JVY A;  1CVW L;  5FDQ A;  4G1M B;  4BXS A;  4COX A;  5L2Z L;  3KQE L;  1X7A L;  2ADX A;  1TPG A;  2P93 L;  1NFW B;  1CCV A;  1YO8 A;  4CUE A;  2D1J B;  1AUT L;  3C9A C;  3ASI A;  1EPI A;  5EGM B;  2BOK L;  2WYJ B;  2PHB B;  3QH0 A;  4RUT A;  3QCW A;  1IGZ A;  4NGA L;  2VJ3 A;  3ZYI B;  5CKN A;  4Z6A L;  4D90 A;  3POY A;  4A94 C;  5CIS A;  2Y38 A;  3NJP C;  1XFE A;  2Y5H L;  3P5B L;  2KL7 A;  1IQL L;  4MMX B;  2W3K B;  1EZQ B;  1NFU B;  5F19 A;  3ENS A;  1KLJ L;  3KRK A;  3QMO A;  2WG3 C;  4AQT A;  4MMZ B;  3GCX E;  2W2P E;  2J95 B;  4BTT A;  2MHP A;  1NT0 A;  4BDW A;  2XBX L;  1G2L B;  4ZXX L;  1BF9 A;  2FLR L;  1DQB A;  2YGO A;  2WPH E;  4ZXY L;  5JBB E;  5COX A;  2J94 B;  1PFX L;  2DDU A;  1IQH L;  2YGP A;  4X8T L;  1ZAQ A;  1U8C B;  2Y7X B;  1A3P A;  3TZI A;  3NT1 A;  4ISI L;  1APQ A;  1J9C L;  3TGF A;  5KIR A;  1P9J A;  1L5G B;  2P3U A;  1FE2 A;  1NZI A;  2VWL L;  3N8W B;  3BT2 A;  1WHF A;  1FAK L;  1CCF A;  2G00 L;  1MQ5 L;  1DDX A;  1ATD A;  3N8Y B;  5JBA E;  5F1A A;  2P16 L;  3U73 A;  3HS5 A;  1KLO A;  1KIG L;  3ZYG A;  4X8U L;  1PRH A;  3M36 L;  1FJS L;  4Y76 B;  4JZD L;  4RS0 A;  4X8V L;  1HAE A;  3HS6 A;  4M11 A;  1LMM A;  2EI7 B;  4ZHA B;  2FD6 A;  2RA0 L;  1ATA A;  3K9X A;  3TH3 L;  1IOE L;  4O1Z A;  1N7D A;  1JBU L;  2J38 B;  4BTU A;  2VH6 B;  2WPM E;  1TOZ A;  3ZYJ B;  5IKR A;  1WHE A;  2XBV L;  2W26 B;  4CUF A;  1IQN L;  1EMO A;  4PH9 A;  1K37 A;  2BOH A;  1IVO C;  1PXX A;  2XBW L;  1YUG A;  2H9E C;  4JYU L;  2P3T A;  1HRF A;  4YT6 L;  3KCG L;  3TK6 B;  5L30 L;  1EPG A;  3CFW A;  4D0E A;  3LAQ A;  4CSY A;  2WYG B;  1CVU A;  2Y81 B;  1EGF A;  5JBC E;  2UWL B;  1DX5 I;  3HO4 A;  2BO2 A;  2JKH L;  2FLB L;  3N8W A;  2M74 A;  2W2O E;  4NA9 L;  1YGC L;  2RNL A;  3OLU A;  1IOX A;  2VWM K;  1W7X L;  2W2N E;  2VVU L;  2VVC K;  4CUD A;  5JB8 E;  3KK6 A;  1CEJ A;  4OTY A;  2Y5G L;  3N8Y A;  3KQD L;  2WFX B;  1UZK A;  4BTI A;  1LPG A;  1XKA L;  3V65 B;  3KQB L;  3Q7D A;  5IKV A;  5JW1 A;  4ISH L;  4LOR A;  2BOX A;  4JYV L;  1NPE B;  1DIY A;  3V64 C;  4ZH8 B;  2KB9 A;  3U7U G;  1O5D L;  2VWO L;  3PGH A;  2BQ6 A;  2Y80 B;  1XKB A;  3LTG D;  3RR3 A;  2PUQ L;  2P94 L;  2WPL E;  2Y82 B;  3N8X A;  3GCW E;  1CX2 A;  5IKQ A;  4LMF A;  3FCS B;  3GIS X;  3SW2 A;  1URK A;  1C5M F;  1G1S A;  3NTB A;  3BT1 A;  2NPR A;  2VH0 B;  1Q4G A;  1APO A;  3BPS E;  2EI6 B;  1UZP A;  3CA7 A;  1IGX A;  3CEN L;  1FF7 A;  5CKQ A;  1HAF A;  4BDX A;  2FZZ L;  1FAX L;  5KN5 C;  2OYU P;  1K36 A;  2RHP A;  2J34 B;  3IIT B;  2WG4 B;  4X8S L;  2W3I B;  1NQL B;  3HS7 A;  3LTF B;  1YUF A;  2BQW A;  4YZU B;  1KSN B;  1F7M A;  3H5C B;  4JZE L;  1P0S L;  3LN0 A;  2J4I B;  3EGF A;  3FBY A;  2Y7Z B;  1LPK A;  1IQJ L;  1I0U A;  1IJQ A;  2J2U B;  5I46 L;  3IJE B;  1F7E A;  4XBM A;  1HJ7 A;  2P26 A;  1RFN B;  4E1G A;  3N8Z A;  2EI8 B;  4RRY A;  2P3F L;  2XBY L;  5K0H B;  1PTH A;  4RRW A;  5JB9 E;  1IQM L;  2XC5 L;  1U67 A;  3S6X A;  2MGP A;  3LC3 B;  5L2Y L;  2CJI B;  2MGR A;  2TGF A;  2K2S B;  1GK5 A;  2P95 L;  3Q3K B;  4RRZ A;  1F0S B;  4ZAE B;  1MQ6 L;  1NFY B;  2BOU A;  1FSB A;  1V3X B;  2KV4 A;  2XC0 L;  2FLG A;  1L3Y A;  1JL9 A;  1MOX C;  2UWO B;  3N8V A;  1G1Q A;  1FFM A;  3TK5 B;  3MDL A;  4M10 A;  1G1R A;  4BXW A;  3ELA L;  4O02 B;  1IQI L;  3MQE A;  4JZF L;  3HO5 A;  3KL6 B;  1LPZ A;  1CQE A;  2YGQ A;  1IP0 A;  4A7I A;  1LQD A;  5JVZ A;  4Z0K B;  3SOQ A;  4XLW A;  2H9E L;  4Y6D B;  1KLI L;  2BMG A;  1IQK L;  3HPT A;  2K2T A;  3TBD A;  3DEM A;  6COX A;  2WFT A;  1HT8 A;  3F6U L;  3CS7 L;  1EMN A;  1SZB A;  1IQF L;  2W86 A;  2W2Q E;  4Y7A B;  3LIW B;  3R05 A;  2B7D L;  4Y7B B;  4Z0L A;  2GD4 A;  1WU1 B;  3F1S B;  1EPJ A;  2Q1J B;  3NTG A;  1UZJ A;  1TLE A;  2P3F N;  1IQE L;  4OTJ A;  1NFX B;  5E8D A;  2VWN L;  2OYE P;  4YT7 L;  2AYL A;  2I9B A;  1ATE A;  1EAI C;  1HX2 A;  1HRE A;  3SOV A;  1HT5 A;  1G1T A;  1HZ8 A;  4C16 A;  1COU A;  1LMJ A;  3HO3 A;  1EQH A;  2W2M E;  2UWP B;  3OLT A;  3FFG L;  4D0F A;  1EPH A;  4Y71 B;  2WPJ E;  2BZ6 L;  2WPI E;  2WZP P;  2PR3 B;  1UZQ A;  1EBV A;  1F0R B;  2XC4 L;  2P28 B;  1IQG L;  3SOB B;  1M1X B;  1YUK B;  4FM5 A;  1OB1 C;  5CKM A;  1EQG A;  4Y79 B;  1HCG B;  2WPK E;  1QFK L;  2F9B L;  3LN1 A;  3M37 L;  1PGE A;  2Y5F L;  1ADX A;  3KQC L;  2VVV L;  4XL1 A;  1XDT R;  2KNI A;  1N1I A;  3LC5 B;  4MMY B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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