4X8VL

Factor viia in complex with the inhibitor (methyl {3-[(2r)-1-{(2r)-2-(3,4-dimethoxyphenyl)-2-[(1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]acetyl}pyrrolidin-2-yl]-4-(propan-2-ylsulfonyl)phenyl}carbamate)
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
55
structure length
55
Chain Sequence
ICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Novel P1 Groups for Coagulation Factor VIIa Inhibition Using Fragment-Based Screening.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Factor VIIa (Heavy Chain)
total genus 12
structure length 55
sequence length 55
ec nomenclature ec 3.4.21.21: Coagulation factor VIIa.
pdb deposition date 2014-12-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 4x8vL00
1U8CB 2VVCK 2VJ3A 2WG4B 3C9AC 5F1AA 2Y5HL 3N8YA 2BQWA 4NGAL 2P3UA 5IKQA 3TH3L 3ZYGA 3K9XA 1WHEA 1XFEA 2TGFA 1I0UA 2WPME 4LMFA 4X8VL 4YT6L 1IVOC 4MMZB 4ZAEB 3NTBA 4Y6DB 3KQBL 5EGMB 1F0RB 3NTGA 5CKNA 1XDTR 2WPLE 1V3XB 4O02B 4NG9L 1HCGB 2WPKE 4CSYA 1IGZA 1IGXA 2CJIB 2W2ME 2FD6A 2RHPA 2B7DL 1MOXC 2P95L 3M37L 4NA9L 4FM5A 2OYUP 1DDXA 2WPJE 1AUTL 1NT0A 1FJSL 4RRWA 4COXA 2VWLL 1LPKA 1NQLB 3SW2A 6COXA 1IQJL 2I9AA 2P3FN 1HAFA 3N8WA 2BO2A 2D1JB 2PHBB 2JKHL 2UWPB 2KL7A 2VVVL 3HS5A 1Q4GA 1F0SB 4Y7BB 2G00L 4Y71B 2Y5FL 2FLRL 1PTHA 1WHFA 2J2UB 4ZXYL 1IJQA 1LPGA 2GD4A 1DQBA 3QMOA 1SZBA 1G2LB 4RUTA 2W3KB 4RS0A 1O5DL 2Y7XB 3LC5B 3ASIA 4JYVL 3TGFA 2MGPA 4JZFL 3LIWB 1BF9A 1EQHA 1EGFA 4RRXA 1J9CL 1A3PA 1B9WA 1WU1B 1OB1C 1MQ6L 2DDUA 1PRHA 4OTYA 1PXXA 2VVUL 3CA7A 2P93L 1F7EA 1ADXA 5CISA 2WPIE 3FCSB 3N8VA 4CUEA 2PR3B 1EPJA 3GCWE 1FF7A 2J95B 1IQIL 4E1GA 1LMJA 1IQLL 3Q3KB 1IQEL 4BDWA 1NZIA 2W2PE 4A7IA 4BTUA 4OTJA 1C5MF 3KK6A 4ZHAB 4TGFA 1CVUA 2XBWL 1GK5A 1Z6EL 3N8ZA 5JBAE 1X7AL 4CUDA 3HO3A 1ATBA 2VWOL 2VWNL 1XKAL 2XC4L 1IQGL 2I9BA 1IQFL 1CVWL 1IQML 5JVZA 3TZIA 3ENSA 1YUKB 4X8TL 3HO5A 1HZ8A 2EI7B 1HT5A 1TPGA 5JB8E 2P16L 4RRYA 4D0FA 3LAQA 1G1RA 2XC0L 3U7UG 3KQCL 4BDXA 2BQ6A 2AYLA 2WG3C 5JW1A 4XL1A 4ZXXL 1K37A 1DVAL 4LORA 2BOKL 2YGOA 3N8YB 1TLEA 2KV4A 4ZH8B 1IQNL 1MQ5L 4Y79B 5E8DA 1YUFA 4M10A 4O1ZA 3ZYIB 4JYUL 2KB9A 5IKTA 3NT1A 3OLTA 1CX2A 2PUQL 3P5BL 2P26A 2W2QE 1UZPA 1G1QA 1ATEA 2Q1JB 1DIYA 2EI6B 5JB9E 2J38B 1YUGA 2VWMK 1EBVA 1LPZA 2FZZL 1URKA 2W26B 1KLOA 3GCXE 5KIRA 1JL9A 1M1XB 1CCVA 5JBCE 2FLGA 3BT2A 1YGCL 2Y38A 3DEMA 3HS6A 3LTGD 1JBUL 1FAKL 2W3IB 3R05A 1HRFA 5JVYA 4ISIL 2Y5GL 3N8WB 2WFTA 4MMYB 1W7XL 1APQA 5JBBE 3KL6B 1G1SA 1YO8A 4XBMA 1IQHL 5KN5C 1HT8A 2XC5L 5IKRA 4BXSA 1EAIC 3CFWA 2Y7ZB 1U67A 4D0EA 4RRZA 2UWOB 1XKBA 2WYJB 3TK6B 3V65B 2MHPA 3TK5B 2ADXA 5CKQA 2BMGA 1JV2B 1CCFA 2XBYL 2J4IB 1KLIL 2EI8B 3F1SB 3HPTA 5L2YL 3MDLA 2BOXA 3LN1A 4CUFA 2P28B 1LQDA 3V64C 1L3YA 2M74A 3KCGL 1PFXL 3PGHA 1HX2A 2K2SB 4YT7L 1DX5I 1APOA 1KSNB 1Z6CA 3POYA 1KLJL 5CKMA 3ZYJB 1HJ7A 3LN0A 3U73A 2WFXB 3HS7A 2H9EL 3BPSE 4C16A 2YGPA 1IOEL 1L5GB 2P3FL 1EQGA 3CS7L 3KRKA 4D90A 1TOZA 2OYEP 1W8BL 1COUA 1KIGL 2UWLB 4BXWA 2BQ7A 2RA0L 1UZJA 1N7DA 1CEJA 3EGFA 2BOHA 5K0HB 2VH6B 2Y82B 1PGEA 2NPRA 4Z6AL 1ZAQA 1NFXB 3FBYA 1UZQA 4JZEL 2FLBL 4ISHL 2W2NE 3LTFB 4X8UL 3H5CB 1HAEA 2WYGB 1HREA 3TBDA 4Y76B 4BTTA 1ATDA 2RNLA 3LC3B 1G2MB 1IQKL 3SOQA 1NFUB 2W2OE 3IJEB 4MMXB 3BT1A 1F7MA 3GISX 3NJPC 1NFYB 4Z0LA 1K36A 3KQDL 4YZUB 5IKVA 5FDQA 3ELAL 2VH0B 4BTIA 5L2ZL 4PH9A 2J34B 4JZDL 2BZ6L 3Q7DA 2BOUA 3RR3A 2P94L 1EPIA 1N1IA 1EZQB 1QFKL 5COXA 1EMNA 2P3TA 2XBVL 1NPEB 2F9BL 1UZKA 5F19A 1ATAA 1IP0A 1CQEA 4XLWA 1FFMA 4Y7AB 1P0SL 3IITB 4AQTA 4X8SL 3M36L 1G1TA 2J94B 1FE2A 3N8XA 2Y81B 1IOXA 2XBXL 1FSBA 2WPHE 1EPHA 4G1MB 2Y80B 1FAXL 3HO4A 3SOBB 1EMOA 3KQEL 5L30L 3SOVA 2K2TA 3MQEA 4M11A 3QCWA 3F6UL 5I46L 2W86A 4Z0KB 3QH0A 3FFGL 3CENL 1EPGA 1NFWB 2MGRA 3OLUA 1P9JA 1RFNB
chains in the Genus database with same CATH superfamily
1U8CB 2VVCK 2VJ3A 2WG4B 3C9AC 5F1AA 2Y5HL 3N8YA 2BQWA 4NGAL 2P3UA 5IKQA 3TH3L 3ZYGA 3K9XA 1WHEA 1XFEA 2TGFA 1I0UA 2WPME 4LMFA 4X8VL 4YT6L 1IVOC 4MMZB 4ZAEB 3NTBA 4GU4A 4Y6DB 3KQBL 5EGMB 1F0RB 3NTGA 5CKNA 1XDTR 2WPLE 1V3XB 4O02B 4NG9L 1HCGB 2WPKE 4CSYA 1IGZA 1IGXA 2CJIB 2W2ME 2FD6A 2RHPA 2B7DL 1MOXC 2P95L 3M37L 4NA9L 4FM5A 2OYUP 1DDXA 2WPJE 1AUTL 1NT0A 1FJSL 4RRWA 4COXA 2VWLL 2HOXA 1LPKA 1NQLB 3SW2A 6COXA 1IQJL 2I9AA 2P3FN 1HAFA 3N8WA 2BO2A 2D1JB 2PHBB 2JKHL 4GU3A 2UWPB 2KL7A 2VVVL 3HS5A 1Q4GA 1F0SB 4Y7BB 2G00L 4Y71B 2Y5FL 2FLRL 1PTHA 1WHFA 2J2UB 4ZXYL 1IJQA 1LPGA 2GD4A 1DQBA 3QMOA 1SZBA 1G2LB 4RUTA 2BT8A 2W3KB 4RS0A 1O5DL 2Y7XB 3LC5B 3ASIA 4JYVL 3TGFA 2MGPA 4JZFL 3LIWB 1BF9A 1EQHA 1EGFA 4RRXA 1J9CL 1A3PA 1B9WA 1WU1B 1OB1C 1MQ6L 2DDUA 1PRHA 4OTYA 1PXXA 2VVUL 3CA7A 2P93L 1F7EA 1ADXA 5CISA 2WPIE 3FCSB 3N8VA 4CUEA 2PR3B 1EPJA 3GCWE 1FF7A 2J95B 1IQIL 4E1GA 1LMJA 1IQLL 3Q3KB 1IQEL 4BDWA 1NZIA 2W2PE 4A7IA 1LMMA 4BTUA 4OTJA 1C5MF 3KK6A 4ZHAB 4TGFA 1CVUA 2KNIA 2XBWL 1GK5A 1Z6EL 2BSFA 3N8ZA 5JBAE 1X7AL 4CUDA 3HO3A 1ATBA 2VWOL 2VWNL 1XKAL 2XC4L 1IQGL 2I9BA 1IQFL 1CVWL 1IQML 5JVZA 3TZIA 3ENSA 1YUKB 4X8TL 3HO5A 1HZ8A 2EI7B 1HT5A 1TPGA 5JB8E 2P16L 4RRYA 4D0FA 3LAQA 1G1RA 2XC0L 3U7UG 3KQCL 4BDXA 3S6XA 2BQ6A 2AYLA 2WG3C 5JW1A 4XL1A 4ZXXL 1K37A 1DVAL 4LORA 2BOKL 2YGOA 3N8YB 1TLEA 2KV4A 4ZH8B 1IQNL 1MQ5L 4Y79B 5E8DA 1YUFA 4M10A 4O1ZA 3ZYIB 4JYUL 2KB9A 5IKTA 3NT1A 3OLTA 1CX2A 2PUQL 3P5BL 2P26A 2W2QE 1UZPA 1G1QA 1ATEA 2Q1JB 1DIYA 2EI6B 5JB9E 2J38B 1YUGA 2VWMK 1EBVA 1LPZA 2FZZL 1URKA 2W26B 1KLOA 3GCXE 5KIRA 1JL9A 1M1XB 1CCVA 5JBCE 2FLGA 3BT2A 1YGCL 2Y38A 3DEMA 3HS6A 3LTGD 1JBUL 1FAKL 2W3IB 3R05A 1HRFA 5JVYA 4ISIL 1LK9A 2Y5GL 3N8WB 2WFTA 4MMYB 1W7XL 1APQA 5JBBE 3KL6B 1G1SA 1YO8A 4XBMA 1IQHL 5KN5C 1HT8A 2XC5L 5IKRA 4BXSA 1EAIC 3CFWA 2Y7ZB 1U67A 4A94C 4D0EA 4RRZA 2UWOB 1XKBA 2WYJB 3TK6B 3V65B 2MHPA 3TK5B 2ADXA 5CKQA 2BMGA 1JV2B 1CCFA 2XBYL 2J4IB 1KLIL 2EI8B 3F1SB 3HPTA 5L2YL 3MDLA 2BOXA 3LN1A 4CUFA 2P28B 1LQDA 3V64C 1L3YA 2M74A 3KCGL 1PFXL 3PGHA 1HX2A 2K2SB 4YT7L 2BT7A 1DX5I 1APOA 1KSNB 1V1HA 1Z6CA 3POYA 1KLJL 5CKMA 3ZYJB 1HJ7A 3LN0A 3U73A 2WFXB 3HS7A 2H9EL 3BPSE 4C16A 2YGPA 1IOEL 1L5GB 2P3FL 1EQGA 3CS7L 3KRKA 4D90A 1TOZA 2OYEP 1W8BL 1COUA 1KIGL 2H9EC 1V1IA 2UWLB 2BQ7A 4BXWA 2RA0L 1UZJA 1N7DA 1CEJA 3EGFA 2BOHA 5K0HB 2VH6B 2Y82B 1PGEA 2NPRA 4Z6AL 1ZAQA 1NFXB 3FBYA 1UZQA 4JZEL 2FLBL 2HORA 4ISHL 2JJLA 2W2NE 2YGQA 3LTFB 4X8UL 3H5CB 1HAEA 2WYGB 2WZPP 1HREA 3TBDA 4Y76B 4BTTA 1ATDA 2RNLA 3LC3B 1G2MB 1IQKL 3SOQA 1NFUB 2W2OE 3IJEB 4MMXB 3BT1A 1F7MA 3GISX 3NJPC 1NFYB 4Z0LA 1K36A 1KKEA 3KQDL 4YZUB 5IKVA 5FDQA 3ELAL 2VH0B 4BTIA 1QIUA 5L2ZL 4PH9A 2J34B 4JZDL 2BZ6L 3Q7DA 2BOUA 3RR3A 2P94L 1EPIA 1N1IA 1EZQB 1QFKL 5COXA 1EMNA 2P3TA 2XBVL 1NPEB 2F9BL 1UZKA 5F19A 1ATAA 1IP0A 1CQEA 4XLWA 1FFMA 4Y7AB 1P0SL 3IITB 4AQTA 4X8SL 3M36L 1G1TA 2J94B 1FE2A 3N8XA 2Y81B 1IOXA 2XBXL 1FSBA 2WPHE 1EPHA 4G1MB 2Y80B 1FAXL 3HO4A 3SOBB 1EMOA 3KQEL 5L30L 3SOVA 2K2TA 3MQEA 4M11A 2VRSA 3QCWA 3F6UL 5I46L 2W86A 4Z0KB 3QH0A 3FFGL 3CENL 1EPGA 1NFWB 2MGRA 3OLUA 1P9JA 1RFNB
chains in the Genus database with same CATH topology
1U8CB 2VVCK 2VJ3A 2WG4B 3C9AC 5F1AA 2Y5HL 3N8YA 2BQWA 4NGAL 2P3UA 5IKQA 3TH3L 3ZYGA 3K9XA 1WHEA 1XFEA 2TGFA 1I0UA 2WPME 4LMFA 4X8VL 4YT6L 1IVOC 4MMZB 4ZAEB 3NTBA 4Y6DB 3KQBL 5EGMB 1F0RB 3NTGA 5CKNA 1XDTR 2WPLE 1V3XB 4O02B 4NG9L 1HCGB 2WPKE 4CSYA 1IGZA 1IGXA 2CJIB 2W2ME 2FD6A 2RHPA 2B7DL 1MOXC 2P95L 3M37L 4NA9L 4FM5A 2OYUP 1DDXA 2WPJE 1AUTL 1NT0A 1FJSL 4RRWA 4COXA 2VWLL 1LPKA 1NQLB 3SW2A 6COXA 1IQJL 2I9AA 2P3FN 1HAFA 3N8WA 2BO2A 2D1JB 2PHBB 2JKHL 2UWPB 2KL7A 2VVVL 3HS5A 1Q4GA 1F0SB 4Y7BB 2G00L 4Y71B 2Y5FL 2FLRL 1PTHA 1WHFA 2J2UB 4ZXYL 1IJQA 1LPGA 2GD4A 1DQBA 3QMOA 1SZBA 1G2LB 4RUTA 2W3KB 4RS0A 1O5DL 2Y7XB 3LC5B 3ASIA 4JYVL 3TGFA 2MGPA 4JZFL 3LIWB 1BF9A 1EQHA 1EGFA 4RRXA 1J9CL 1A3PA 1B9WA 1WU1B 1OB1C 1MQ6L 2DDUA 1PRHA 4OTYA 1PXXA 2VVUL 3CA7A 2P93L 1F7EA 1ADXA 5CISA 2WPIE 3FCSB 3N8VA 4CUEA 2PR3B 1EPJA 3GCWE 1FF7A 2J95B 1IQIL 4E1GA 1LMJA 1IQLL 3Q3KB 1IQEL 4BDWA 1NZIA 2W2PE 4A7IA 1LMMA 4BTUA 4OTJA 1C5MF 3KK6A 4ZHAB 4TGFA 1CVUA 2KNIA 2XBWL 1GK5A 1Z6EL 3N8ZA 5JBAE 1X7AL 4CUDA 3HO3A 1ATBA 2VWOL 2VWNL 1XKAL 2XC4L 1IQGL 2I9BA 1IQFL 1CVWL 1IQML 5JVZA 3TZIA 3ENSA 1YUKB 4X8TL 3HO5A 1HZ8A 2EI7B 1HT5A 1TPGA 5JB8E 2P16L 4RRYA 4D0FA 3LAQA 1G1RA 2XC0L 3U7UG 3KQCL 4BDXA 3S6XA 2BQ6A 2AYLA 2WG3C 5JW1A 4XL1A 4ZXXL 1K37A 1DVAL 4LORA 2BOKL 2YGOA 3N8YB 1TLEA 2KV4A 4ZH8B 1IQNL 1MQ5L 4Y79B 5E8DA 1YUFA 4M10A 4O1ZA 3ZYIB 4JYUL 2KB9A 5IKTA 3NT1A 3OLTA 1CX2A 2PUQL 3P5BL 2P26A 2W2QE 1UZPA 1G1QA 1ATEA 2Q1JB 1DIYA 2EI6B 5JB9E 2J38B 1YUGA 2VWMK 1EBVA 1LPZA 2FZZL 1URKA 2W26B 1KLOA 3GCXE 5KIRA 1JL9A 1M1XB 1CCVA 5JBCE 2FLGA 3BT2A 1YGCL 2Y38A 3DEMA 3HS6A 3LTGD 1JBUL 1FAKL 2W3IB 3R05A 1HRFA 5JVYA 4ISIL 2Y5GL 3N8WB 2WFTA 4MMYB 1W7XL 1APQA 5JBBE 3KL6B 1G1SA 1YO8A 4XBMA 1IQHL 5KN5C 1HT8A 2XC5L 5IKRA 4BXSA 1EAIC 3CFWA 2Y7ZB 1U67A 4A94C 4D0EA 4RRZA 2UWOB 1XKBA 2WYJB 3TK6B 3V65B 2MHPA 3TK5B 2ADXA 5CKQA 2BMGA 1JV2B 1CCFA 2XBYL 2J4IB 1KLIL 2EI8B 3F1SB 3HPTA 5L2YL 3MDLA 2BOXA 3LN1A 4CUFA 2P28B 1LQDA 3V64C 1L3YA 2M74A 3KCGL 1PFXL 3PGHA 1HX2A 2K2SB 4YT7L 1DX5I 1APOA 1KSNB 1Z6CA 3POYA 1KLJL 5CKMA 3ZYJB 1HJ7A 3LN0A 3U73A 2WFXB 3HS7A 2H9EL 3BPSE 4C16A 2YGPA 1IOEL 1L5GB 2P3FL 1EQGA 3CS7L 3KRKA 4D90A 1TOZA 2OYEP 1W8BL 1COUA 1KIGL 2H9EC 2UWLB 4BXWA 2BQ7A 2RA0L 1UZJA 1N7DA 1CEJA 3EGFA 2BOHA 5K0HB 2VH6B 2Y82B 1PGEA 2NPRA 4Z6AL 1ZAQA 1NFXB 3FBYA 1UZQA 4JZEL 2FLBL 4ISHL 2W2NE 2YGQA 3LTFB 4X8UL 3H5CB 1HAEA 2WYGB 2WZPP 1HREA 3TBDA 4Y76B 4BTTA 1ATDA 2RNLA 3LC3B 1G2MB 1IQKL 3SOQA 1NFUB 2W2OE 3IJEB 4MMXB 3BT1A 1F7MA 3GISX 3NJPC 1NFYB 4Z0LA 1K36A 3KQDL 4YZUB 5IKVA 5FDQA 3ELAL 2VH0B 4BTIA 5L2ZL 4PH9A 2J34B 4JZDL 2BZ6L 3Q7DA 2BOUA 3RR3A 2P94L 1EPIA 1N1IA 1EZQB 1QFKL 5COXA 1EMNA 2P3TA 2XBVL 1NPEB 2F9BL 1UZKA 5F19A 1ATAA 1IP0A 1CQEA 4XLWA 1FFMA 4Y7AB 1P0SL 3IITB 4AQTA 4X8SL 3M36L 1G1TA 2J94B 1FE2A 3N8XA 2Y81B 1IOXA 2XBXL 1FSBA 2WPHE 1EPHA 4G1MB 2Y80B 1FAXL 3HO4A 3SOBB 1EMOA 3KQEL 5L30L 3SOVA 2K2TA 3MQEA 4M11A 3QCWA 3F6UL 5I46L 2W86A 4Z0KB 3QH0A 3FFGL 3CENL 1EPGA 1NFWB 2MGRA 3OLUA 1P9JA 1RFNB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1U8C B;  2VVC K;  2VJ3 A;  2WG4 B;  3C9A C;  5F1A A;  2Y5H L;  3N8Y A;  2BQW A;  4NGA L;  2P3U A;  5IKQ A;  3TH3 L;  3ZYG A;  3K9X A;  1WHE A;  1XFE A;  2TGF A;  1I0U A;  2WPM E;  4LMF A;  4X8V L;  4YT6 L;  1IVO C;  4MMZ B;  4ZAE B;  3NTB A;  4Y6D B;  3KQB L;  5EGM B;  1F0R B;  3NTG A;  5CKN A;  1XDT R;  2WPL E;  1V3X B;  4O02 B;  4NG9 L;  1HCG B;  2WPK E;  4CSY A;  1IGZ A;  1IGX A;  2CJI B;  2W2M E;  2FD6 A;  2RHP A;  2B7D L;  1MOX C;  2P95 L;  3M37 L;  4NA9 L;  4FM5 A;  2OYU P;  1DDX A;  2WPJ E;  1AUT L;  1NT0 A;  1FJS L;  4RRW A;  4COX A;  2VWL L;  1LPK A;  1NQL B;  3SW2 A;  6COX A;  1IQJ L;  2I9A A;  2P3F N;  1HAF A;  3N8W A;  2BO2 A;  2D1J B;  2PHB B;  2JKH L;  2UWP B;  2KL7 A;  2VVV L;  3HS5 A;  1Q4G A;  1F0S B;  4Y7B B;  2G00 L;  4Y71 B;  2Y5F L;  2FLR L;  1PTH A;  1WHF A;  2J2U B;  4ZXY L;  1IJQ A;  1LPG A;  2GD4 A;  1DQB A;  3QMO A;  1SZB A;  1G2L B;  4RUT A;  2W3K B;  4RS0 A;  1O5D L;  2Y7X B;  3LC5 B;  3ASI A;  4JYV L;  3TGF A;  2MGP A;  4JZF L;  3LIW B;  1BF9 A;  1EQH A;  1EGF A;  4RRX A;  1J9C L;  1A3P A;  1B9W A;  1WU1 B;  1OB1 C;  1MQ6 L;  2DDU A;  1PRH A;  4OTY A;  1PXX A;  2VVU L;  3CA7 A;  2P93 L;  1F7E A;  1ADX A;  5CIS A;  2WPI E;  3FCS B;  3N8V A;  4CUE A;  2PR3 B;  1EPJ A;  3GCW E;  1FF7 A;  2J95 B;  1IQI L;  4E1G A;  1LMJ A;  1IQL L;  3Q3K B;  1IQE L;  4BDW A;  1NZI A;  2W2P E;  4A7I A;  4BTU A;  4OTJ A;  1C5M F;  3KK6 A;  4ZHA B;  4TGF A;  1CVU A;  2XBW L;  1GK5 A;  1Z6E L;  3N8Z A;  5JBA E;  1X7A L;  4CUD A;  3HO3 A;  1ATB A;  2VWO L;  2VWN L;  1XKA L;  2XC4 L;  1IQG L;  2I9B A;  1IQF L;  1CVW L;  1IQM L;  5JVZ A;  3TZI A;  3ENS A;  1YUK B;  4X8T L;  3HO5 A;  1HZ8 A;  2EI7 B;  1HT5 A;  1TPG A;  5JB8 E;  2P16 L;  4RRY A;  4D0F A;  3LAQ A;  1G1R A;  2XC0 L;  3U7U G;  3KQC L;  4BDX A;  2BQ6 A;  2AYL A;  2WG3 C;  5JW1 A;  4XL1 A;  4ZXX L;  1K37 A;  1DVA L;  4LOR A;  2BOK L;  2YGO A;  3N8Y B;  1TLE A;  2KV4 A;  4ZH8 B;  1IQN L;  1MQ5 L;  4Y79 B;  5E8D A;  1YUF A;  4M10 A;  4O1Z A;  3ZYI B;  4JYU L;  2KB9 A;  5IKT A;  3NT1 A;  3OLT A;  1CX2 A;  2PUQ L;  3P5B L;  2P26 A;  2W2Q E;  1UZP A;  1G1Q A;  1ATE A;  2Q1J B;  1DIY A;  2EI6 B;  5JB9 E;  2J38 B;  1YUG A;  2VWM K;  1EBV A;  1LPZ A;  2FZZ L;  1URK A;  2W26 B;  1KLO A;  3GCX E;  5KIR A;  1JL9 A;  1M1X B;  1CCV A;  5JBC E;  2FLG A;  3BT2 A;  1YGC L;  2Y38 A;  3DEM A;  3HS6 A;  3LTG D;  1JBU L;  1FAK L;  2W3I B;  3R05 A;  1HRF A;  5JVY A;  4ISI L;  2Y5G L;  3N8W B;  2WFT A;  4MMY B;  1W7X L;  1APQ A;  5JBB E;  3KL6 B;  1G1S A;  1YO8 A;  4XBM A;  1IQH L;  5KN5 C;  1HT8 A;  2XC5 L;  5IKR A;  4BXS A;  1EAI C;  3CFW A;  2Y7Z B;  1U67 A;  4D0E A;  4RRZ A;  2UWO B;  1XKB A;  2WYJ B;  3TK6 B;  3V65 B;  2MHP A;  3TK5 B;  2ADX A;  5CKQ A;  2BMG A;  1JV2 B;  1CCF A;  2XBY L;  2J4I B;  1KLI L;  2EI8 B;  3F1S B;  3HPT A;  5L2Y L;  3MDL A;  2BOX A;  3LN1 A;  4CUF A;  2P28 B;  1LQD A;  3V64 C;  1L3Y A;  2M74 A;  3KCG L;  1PFX L;  3PGH A;  1HX2 A;  2K2S B;  4YT7 L;  1DX5 I;  1APO A;  1KSN B;  1Z6C A;  3POY A;  1KLJ L;  5CKM A;  3ZYJ B;  1HJ7 A;  3LN0 A;  3U73 A;  2WFX B;  3HS7 A;  2H9E L;  3BPS E;  4C16 A;  2YGP A;  1IOE L;  1L5G B;  2P3F L;  1EQG A;  3CS7 L;  3KRK A;  4D90 A;  1TOZ A;  2OYE P;  1W8B L;  1COU A;  1KIG L;  2UWL B;  4BXW A;  2BQ7 A;  2RA0 L;  1UZJ A;  1N7D A;  1CEJ A;  3EGF A;  2BOH A;  5K0H B;  2VH6 B;  2Y82 B;  1PGE A;  2NPR A;  4Z6A L;  1ZAQ A;  1NFX B;  3FBY A;  1UZQ A;  4JZE L;  2FLB L;  4ISH L;  2W2N E;  3LTF B;  4X8U L;  3H5C B;  1HAE A;  2WYG B;  1HRE A;  3TBD A;  4Y76 B;  4BTT A;  1ATD A;  2RNL A;  3LC3 B;  1G2M B;  1IQK L;  3SOQ A;  1NFU B;  2W2O E;  3IJE B;  4MMX B;  3BT1 A;  1F7M A;  3GIS X;  3NJP C;  1NFY B;  4Z0L A;  1K36 A;  3KQD L;  4YZU B;  5IKV A;  5FDQ A;  3ELA L;  2VH0 B;  4BTI A;  5L2Z L;  4PH9 A;  2J34 B;  4JZD L;  2BZ6 L;  3Q7D A;  2BOU A;  3RR3 A;  2P94 L;  1EPI A;  1N1I A;  1EZQ B;  1QFK L;  5COX A;  1EMN A;  2P3T A;  2XBV L;  1NPE B;  2F9B L;  1UZK A;  5F19 A;  1ATA A;  1IP0 A;  1CQE A;  4XLW A;  1FFM A;  4Y7A B;  1P0S L;  3IIT B;  4AQT A;  4X8S L;  3M36 L;  1G1T A;  2J94 B;  1FE2 A;  3N8X A;  2Y81 B;  1IOX A;  2XBX L;  1FSB A;  2WPH E;  1EPH A;  4G1M B;  2Y80 B;  1FAX L;  3HO4 A;  3SOB B;  1EMO A;  3KQE L;  5L30 L;  3SOV A;  2K2T A;  3MQE A;  4M11 A;  3QCW A;  3F6U L;  5I46 L;  2W86 A;  4Z0K B;  3QH0 A;  3FFG L;  3CEN L;  1EPG A;  1NFW B;  2MGR A;  3OLU A;  1P9J A;  1RFN B; 
#chains in the Genus database with same CATH topology
 1U8C B;  2VVC K;  2VJ3 A;  2WG4 B;  3C9A C;  5F1A A;  2Y5H L;  3N8Y A;  2BQW A;  4NGA L;  2P3U A;  5IKQ A;  3TH3 L;  3ZYG A;  3K9X A;  1WHE A;  1XFE A;  2TGF A;  1I0U A;  2WPM E;  4LMF A;  4X8V L;  4YT6 L;  1IVO C;  4MMZ B;  4ZAE B;  3NTB A;  4GU4 A;  4Y6D B;  3KQB L;  5EGM B;  1F0R B;  3NTG A;  5CKN A;  1XDT R;  2WPL E;  1V3X B;  4O02 B;  4NG9 L;  1HCG B;  2WPK E;  4CSY A;  1IGZ A;  1IGX A;  2CJI B;  2W2M E;  2FD6 A;  2RHP A;  2B7D L;  1MOX C;  2P95 L;  3M37 L;  4NA9 L;  4FM5 A;  2OYU P;  1DDX A;  2WPJ E;  1AUT L;  1NT0 A;  1FJS L;  4RRW A;  4COX A;  2VWL L;  2HOX A;  1LPK A;  1NQL B;  3SW2 A;  6COX A;  1IQJ L;  2I9A A;  2P3F N;  1HAF A;  3N8W A;  2BO2 A;  2D1J B;  2PHB B;  2JKH L;  4GU3 A;  2UWP B;  2KL7 A;  2VVV L;  3HS5 A;  1Q4G A;  1F0S B;  4Y7B B;  2G00 L;  4Y71 B;  2Y5F L;  2FLR L;  1PTH A;  1WHF A;  2J2U B;  4ZXY L;  1IJQ A;  1LPG A;  2GD4 A;  1DQB A;  3QMO A;  1SZB A;  1G2L B;  4RUT A;  2BT8 A;  2W3K B;  4RS0 A;  1O5D L;  2Y7X B;  3LC5 B;  3ASI A;  4JYV L;  3TGF A;  2MGP A;  4JZF L;  3LIW B;  1BF9 A;  1EQH A;  1EGF A;  4RRX A;  1J9C L;  1A3P A;  1B9W A;  1WU1 B;  1OB1 C;  1MQ6 L;  2DDU A;  1PRH A;  4OTY A;  1PXX A;  2VVU L;  3CA7 A;  2P93 L;  1F7E A;  1ADX A;  5CIS A;  2WPI E;  3FCS B;  3N8V A;  4CUE A;  2PR3 B;  1EPJ A;  3GCW E;  1FF7 A;  2J95 B;  1IQI L;  4E1G A;  1LMJ A;  1IQL L;  3Q3K B;  1IQE L;  4BDW A;  1NZI A;  2W2P E;  4A7I A;  1LMM A;  4BTU A;  4OTJ A;  1C5M F;  3KK6 A;  4ZHA B;  4TGF A;  1CVU A;  2KNI A;  2XBW L;  1GK5 A;  1Z6E L;  2BSF A;  3N8Z A;  5JBA E;  1X7A L;  4CUD A;  3HO3 A;  1ATB A;  2VWO L;  2VWN L;  1XKA L;  2XC4 L;  1IQG L;  2I9B A;  1IQF L;  1CVW L;  1IQM L;  5JVZ A;  3TZI A;  3ENS A;  1YUK B;  4X8T L;  3HO5 A;  1HZ8 A;  2EI7 B;  1HT5 A;  1TPG A;  5JB8 E;  2P16 L;  4RRY A;  4D0F A;  3LAQ A;  1G1R A;  2XC0 L;  3U7U G;  3KQC L;  4BDX A;  3S6X A;  2BQ6 A;  2AYL A;  2WG3 C;  5JW1 A;  4XL1 A;  4ZXX L;  1K37 A;  1DVA L;  4LOR A;  2BOK L;  2YGO A;  3N8Y B;  1TLE A;  2KV4 A;  4ZH8 B;  1IQN L;  1MQ5 L;  4Y79 B;  5E8D A;  1YUF A;  4M10 A;  4O1Z A;  3ZYI B;  4JYU L;  2KB9 A;  5IKT A;  3NT1 A;  3OLT A;  1CX2 A;  2PUQ L;  3P5B L;  2P26 A;  2W2Q E;  1UZP A;  1G1Q A;  1ATE A;  2Q1J B;  1DIY A;  2EI6 B;  5JB9 E;  2J38 B;  1YUG A;  2VWM K;  1EBV A;  1LPZ A;  2FZZ L;  1URK A;  2W26 B;  1KLO A;  3GCX E;  5KIR A;  1JL9 A;  1M1X B;  1CCV A;  5JBC E;  2FLG A;  3BT2 A;  1YGC L;  2Y38 A;  3DEM A;  3HS6 A;  3LTG D;  1JBU L;  1FAK L;  2W3I B;  3R05 A;  1HRF A;  5JVY A;  4ISI L;  1LK9 A;  2Y5G L;  3N8W B;  2WFT A;  4MMY B;  1W7X L;  1APQ A;  5JBB E;  3KL6 B;  1G1S A;  1YO8 A;  4XBM A;  1IQH L;  5KN5 C;  1HT8 A;  2XC5 L;  5IKR A;  4BXS A;  1EAI C;  3CFW A;  2Y7Z B;  1U67 A;  4A94 C;  4D0E A;  4RRZ A;  2UWO B;  1XKB A;  2WYJ B;  3TK6 B;  3V65 B;  2MHP A;  3TK5 B;  2ADX A;  5CKQ A;  2BMG A;  1JV2 B;  1CCF A;  2XBY L;  2J4I B;  1KLI L;  2EI8 B;  3F1S B;  3HPT A;  5L2Y L;  3MDL A;  2BOX A;  3LN1 A;  4CUF A;  2P28 B;  1LQD A;  3V64 C;  1L3Y A;  2M74 A;  3KCG L;  1PFX L;  3PGH A;  1HX2 A;  2K2S B;  4YT7 L;  2BT7 A;  1DX5 I;  1APO A;  1KSN B;  1V1H A;  1Z6C A;  3POY A;  1KLJ L;  5CKM A;  3ZYJ B;  1HJ7 A;  3LN0 A;  3U73 A;  2WFX B;  3HS7 A;  2H9E L;  3BPS E;  4C16 A;  2YGP A;  1IOE L;  1L5G B;  2P3F L;  1EQG A;  3CS7 L;  3KRK A;  4D90 A;  1TOZ A;  2OYE P;  1W8B L;  1COU A;  1KIG L;  2H9E C;  1V1I A;  2UWL B;  2BQ7 A;  4BXW A;  2RA0 L;  1UZJ A;  1N7D A;  1CEJ A;  3EGF A;  2BOH A;  5K0H B;  2VH6 B;  2Y82 B;  1PGE A;  2NPR A;  4Z6A L;  1ZAQ A;  1NFX B;  3FBY A;  1UZQ A;  4JZE L;  2FLB L;  2HOR A;  4ISH L;  2JJL A;  2W2N E;  2YGQ A;  3LTF B;  4X8U L;  3H5C B;  1HAE A;  2WYG B;  2WZP P;  1HRE A;  3TBD A;  4Y76 B;  4BTT A;  1ATD A;  2RNL A;  3LC3 B;  1G2M B;  1IQK L;  3SOQ A;  1NFU B;  2W2O E;  3IJE B;  4MMX B;  3BT1 A;  1F7M A;  3GIS X;  3NJP C;  1NFY B;  4Z0L A;  1K36 A;  1KKE A;  3KQD L;  4YZU B;  5IKV A;  5FDQ A;  3ELA L;  2VH0 B;  4BTI A;  1QIU A;  5L2Z L;  4PH9 A;  2J34 B;  4JZD L;  2BZ6 L;  3Q7D A;  2BOU A;  3RR3 A;  2P94 L;  1EPI A;  1N1I A;  1EZQ B;  1QFK L;  5COX A;  1EMN A;  2P3T A;  2XBV L;  1NPE B;  2F9B L;  1UZK A;  5F19 A;  1ATA A;  1IP0 A;  1CQE A;  4XLW A;  1FFM A;  4Y7A B;  1P0S L;  3IIT B;  4AQT A;  4X8S L;  3M36 L;  1G1T A;  2J94 B;  1FE2 A;  3N8X A;  2Y81 B;  1IOX A;  2XBX L;  1FSB A;  2WPH E;  1EPH A;  4G1M B;  2Y80 B;  1FAX L;  3HO4 A;  3SOB B;  1EMO A;  3KQE L;  5L30 L;  3SOV A;  2K2T A;  3MQE A;  4M11 A;  2VRS A;  3QCW A;  3F6U L;  5I46 L;  2W86 A;  4Z0K B;  3QH0 A;  3FFG L;  3CEN L;  1EPG A;  1NFW B;  2MGR A;  3OLU A;  1P9J A;  1RFN B; 
#chains in the Genus database with same CATH homology
 1U8C B;  2VVC K;  2VJ3 A;  2WG4 B;  3C9A C;  5F1A A;  2Y5H L;  3N8Y A;  2BQW A;  4NGA L;  2P3U A;  5IKQ A;  3TH3 L;  3ZYG A;  3K9X A;  1WHE A;  1XFE A;  2TGF A;  1I0U A;  2WPM E;  4LMF A;  4X8V L;  4YT6 L;  1IVO C;  4MMZ B;  4ZAE B;  3NTB A;  4Y6D B;  3KQB L;  5EGM B;  1F0R B;  3NTG A;  5CKN A;  1XDT R;  2WPL E;  1V3X B;  4O02 B;  4NG9 L;  1HCG B;  2WPK E;  4CSY A;  1IGZ A;  1IGX A;  2CJI B;  2W2M E;  2FD6 A;  2RHP A;  2B7D L;  1MOX C;  2P95 L;  3M37 L;  4NA9 L;  4FM5 A;  2OYU P;  1DDX A;  2WPJ E;  1AUT L;  1NT0 A;  1FJS L;  4RRW A;  4COX A;  2VWL L;  1LPK A;  1NQL B;  3SW2 A;  6COX A;  1IQJ L;  2I9A A;  2P3F N;  1HAF A;  3N8W A;  2BO2 A;  2D1J B;  2PHB B;  2JKH L;  2UWP B;  2KL7 A;  2VVV L;  3HS5 A;  1Q4G A;  1F0S B;  4Y7B B;  2G00 L;  4Y71 B;  2Y5F L;  2FLR L;  1PTH A;  1WHF A;  2J2U B;  4ZXY L;  1IJQ A;  1LPG A;  2GD4 A;  1DQB A;  3QMO A;  1SZB A;  1G2L B;  4RUT A;  2W3K B;  4RS0 A;  1O5D L;  2Y7X B;  3LC5 B;  3ASI A;  4JYV L;  3TGF A;  2MGP A;  4JZF L;  3LIW B;  1BF9 A;  1EQH A;  1EGF A;  4RRX A;  1J9C L;  1A3P A;  1B9W A;  1WU1 B;  1OB1 C;  1MQ6 L;  2DDU A;  1PRH A;  4OTY A;  1PXX A;  2VVU L;  3CA7 A;  2P93 L;  1F7E A;  1ADX A;  5CIS A;  2WPI E;  3FCS B;  3N8V A;  4CUE A;  2PR3 B;  1EPJ A;  3GCW E;  1FF7 A;  2J95 B;  1IQI L;  4E1G A;  1LMJ A;  1IQL L;  3Q3K B;  1IQE L;  4BDW A;  1NZI A;  2W2P E;  4A7I A;  1LMM A;  4BTU A;  4OTJ A;  1C5M F;  3KK6 A;  4ZHA B;  4TGF A;  1CVU A;  2KNI A;  2XBW L;  1GK5 A;  1Z6E L;  3N8Z A;  5JBA E;  1X7A L;  4CUD A;  3HO3 A;  1ATB A;  2VWO L;  2VWN L;  1XKA L;  2XC4 L;  1IQG L;  2I9B A;  1IQF L;  1CVW L;  1IQM L;  5JVZ A;  3TZI A;  3ENS A;  1YUK B;  4X8T L;  3HO5 A;  1HZ8 A;  2EI7 B;  1HT5 A;  1TPG A;  5JB8 E;  2P16 L;  4RRY A;  4D0F A;  3LAQ A;  1G1R A;  2XC0 L;  3U7U G;  3KQC L;  4BDX A;  3S6X A;  2BQ6 A;  2AYL A;  2WG3 C;  5JW1 A;  4XL1 A;  4ZXX L;  1K37 A;  1DVA L;  4LOR A;  2BOK L;  2YGO A;  3N8Y B;  1TLE A;  2KV4 A;  4ZH8 B;  1IQN L;  1MQ5 L;  4Y79 B;  5E8D A;  1YUF A;  4M10 A;  4O1Z A;  3ZYI B;  4JYU L;  2KB9 A;  5IKT A;  3NT1 A;  3OLT A;  1CX2 A;  2PUQ L;  3P5B L;  2P26 A;  2W2Q E;  1UZP A;  1G1Q A;  1ATE A;  2Q1J B;  1DIY A;  2EI6 B;  5JB9 E;  2J38 B;  1YUG A;  2VWM K;  1EBV A;  1LPZ A;  2FZZ L;  1URK A;  2W26 B;  1KLO A;  3GCX E;  5KIR A;  1JL9 A;  1M1X B;  1CCV A;  5JBC E;  2FLG A;  3BT2 A;  1YGC L;  2Y38 A;  3DEM A;  3HS6 A;  3LTG D;  1JBU L;  1FAK L;  2W3I B;  3R05 A;  1HRF A;  5JVY A;  4ISI L;  2Y5G L;  3N8W B;  2WFT A;  4MMY B;  1W7X L;  1APQ A;  5JBB E;  3KL6 B;  1G1S A;  1YO8 A;  4XBM A;  1IQH L;  5KN5 C;  1HT8 A;  2XC5 L;  5IKR A;  4BXS A;  1EAI C;  3CFW A;  2Y7Z B;  1U67 A;  4A94 C;  4D0E A;  4RRZ A;  2UWO B;  1XKB A;  2WYJ B;  3TK6 B;  3V65 B;  2MHP A;  3TK5 B;  2ADX A;  5CKQ A;  2BMG A;  1JV2 B;  1CCF A;  2XBY L;  2J4I B;  1KLI L;  2EI8 B;  3F1S B;  3HPT A;  5L2Y L;  3MDL A;  2BOX A;  3LN1 A;  4CUF A;  2P28 B;  1LQD A;  3V64 C;  1L3Y A;  2M74 A;  3KCG L;  1PFX L;  3PGH A;  1HX2 A;  2K2S B;  4YT7 L;  1DX5 I;  1APO A;  1KSN B;  1Z6C A;  3POY A;  1KLJ L;  5CKM A;  3ZYJ B;  1HJ7 A;  3LN0 A;  3U73 A;  2WFX B;  3HS7 A;  2H9E L;  3BPS E;  4C16 A;  2YGP A;  1IOE L;  1L5G B;  2P3F L;  1EQG A;  3CS7 L;  3KRK A;  4D90 A;  1TOZ A;  2OYE P;  1W8B L;  1COU A;  1KIG L;  2H9E C;  2UWL B;  4BXW A;  2BQ7 A;  2RA0 L;  1UZJ A;  1N7D A;  1CEJ A;  3EGF A;  2BOH A;  5K0H B;  2VH6 B;  2Y82 B;  1PGE A;  2NPR A;  4Z6A L;  1ZAQ A;  1NFX B;  3FBY A;  1UZQ A;  4JZE L;  2FLB L;  4ISH L;  2W2N E;  2YGQ A;  3LTF B;  4X8U L;  3H5C B;  1HAE A;  2WYG B;  2WZP P;  1HRE A;  3TBD A;  4Y76 B;  4BTT A;  1ATD A;  2RNL A;  3LC3 B;  1G2M B;  1IQK L;  3SOQ A;  1NFU B;  2W2O E;  3IJE B;  4MMX B;  3BT1 A;  1F7M A;  3GIS X;  3NJP C;  1NFY B;  4Z0L A;  1K36 A;  3KQD L;  4YZU B;  5IKV A;  5FDQ A;  3ELA L;  2VH0 B;  4BTI A;  5L2Z L;  4PH9 A;  2J34 B;  4JZD L;  2BZ6 L;  3Q7D A;  2BOU A;  3RR3 A;  2P94 L;  1EPI A;  1N1I A;  1EZQ B;  1QFK L;  5COX A;  1EMN A;  2P3T A;  2XBV L;  1NPE B;  2F9B L;  1UZK A;  5F19 A;  1ATA A;  1IP0 A;  1CQE A;  4XLW A;  1FFM A;  4Y7A B;  1P0S L;  3IIT B;  4AQT A;  4X8S L;  3M36 L;  1G1T A;  2J94 B;  1FE2 A;  3N8X A;  2Y81 B;  1IOX A;  2XBX L;  1FSB A;  2WPH E;  1EPH A;  4G1M B;  2Y80 B;  1FAX L;  3HO4 A;  3SOB B;  1EMO A;  3KQE L;  5L30 L;  3SOV A;  2K2T A;  3MQE A;  4M11 A;  3QCW A;  3F6U L;  5I46 L;  2W86 A;  4Z0K B;  3QH0 A;  3FFG L;  3CEN L;  1EPG A;  1NFW B;  2MGR A;  3OLU A;  1P9J A;  1RFN B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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