4YT6L

Factor viia in complex with the inhibitor 4-{[(r)-[5-ethoxy-2-fluoro-3-(propan-2-yloxy)phenyl](4-phenyl-1h-imidazol-2-yl)methyl]amino}benzenecarboximidamide
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
55
structure length
55
Chain Sequence
ICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design and synthesis of potent, selective phenylimidazole-based FVIIa inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Coagulation factor VII (heavy chain)
total genus 13
structure length 55
sequence length 55
ec nomenclature ec 3.4.21.21: Coagulation factor VIIa.
pdb deposition date 2015-03-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 4yt6L00
1NFYB 2WPME 2VWLL 1FAXL 4RRXA 1G1SA 2Y5FL 4G1MB 3ZYGA 1PXXA 2BOKL 1WHFA 2FZZL 2BQWA 1IQEL 3FFGL 1MQ6L 5EGMB 4OTJA 1WHEA 2XC5L 1O5DL 3RR3A 1F0SB 3NJPC 5JB8E 3GISX 4Z0KB 1LPGA 1FAKL 4ZXYL 1KLOA 1G1TA 4Z0LA 2BOXA 2Y82B 4ISHL 3LIWB 5KIRA 1CVWL 3TGFA 2WYJB 1AUTL 1WU1B 3P5BL 3M36L 1KLJL 4ZXXL 3R05A 2EI8B 2Y5GL 1EZQB 2WFTA 4YT6L 3N8WB 1X7AL 5JBCE 3KQCL 5L30L 5JVYA 2WPIE 1KSNB 2VVCK 3N8VA 3V65B 2PHBB 4RUTA 1L3YA 2XBWL 3U73A 4MMZB 2NPRA 3MQEA 2W2PE 4ZHAB 3NT1A 1EMOA 4Y7AB 3N8XA 3BPSE 1URKA 4FM5A 4MMXB 4Y71B 2VWOL 1EAIC 4CUEA 2Y7XB 1EPGA 2WPJE 3ELAL 1NZIA 4E1GA 1FJSL 4LORA 2RNLA 2UWOB 1IGXA 2FLGA 3SOBB 3KCGL 3N8WA 2XC0L 4BTIA 1ZAQA 4RRZA 1G2MB 1HAEA 2MGPA 2P3FN 1Z6EL 3DEMA 5L2ZL 2VH0B 1XKBA 2BO2A 2P93L 2Y7ZB 4LMFA 1M1XB 3ZYJB 4CUFA 1HZ8A 2BMGA 4RS0A 1IQML 3CFWA 1IVOC 2VVUL 2KB9A 1P9JA 4O02B 1NFWB 4M11A 2UWLB 2W3IB 2VWMK 1CCVA 1IQKL 1CCFA 3IJEB 4NGAL 2P26A 5K0HB 3KQDL 1YUKB 3N8YB 5JVZA 1HRFA 1F7MA 2W26B 5I46L 1DIYA 2XBYL 3KK6A 1G1RA 1NFXB 2ADXA 2Y80B 2P28B 4YT7L 4YZUB 3V64C 1HX2A 5IKRA 2MGRA 2W3KB 1QFKL 3ASIA 2BQ7A 2EI6B 2J38B 2XC4L 4Y79B 3LC3B 1JL9A 3KL6B 4BXSA 2VH6B 1LPZA 3LAQA 4X8VL 1A3PA 1F7EA 1KIGL 1EGFA 5IKQA 1MQ5L 1TPGA 2BZ6L 1DX5I 1U8CB 2Y5HL 4BTUA 5FDQA 1DQBA 2J95B 4NA9L 2P95L 2W2OE 1Q4GA 2PR3B 2B7DL 2G00L 2Y38A 1ATEA 1XFEA 4COXA 4A7IA 4D0EA 3K9XA 5JB9E 4CUDA 2WFXB 3POYA 4XL1A 1UZQA 4XLWA 1K36A 2W2ME 2J2UB 1LMJA 3NTBA 1CVUA 1IQGL 1LPKA 2P3TA 1GK5A 1LQDA 1UZJA 1FF7A 2Q1JB 1B9WA 3ZYIB 1IJQA 4RRYA 1L5GB 4CSYA 5CKMA 4BDXA 3BT2A 1IGZA 5JBAE 2P3UA 4O1ZA 4Y76B 4M10A 3EGFA 5CKQA 1PRHA 3SOQA 2EI7B 3HS5A 1ADXA 1KLIL 2OYUP 2FLBL 3CA7A 1EQHA 1IQNL 2PUQL 3HS6A 5CKNA 2KV4A 1YUFA 3Q3KB 1W8BL 4Y7BB 1IOXA 2J4IB 1IOEL 1HAFA 3TBDA 1EBVA 2W86A 2J94B 2J34B 1COUA 1PTHA 4MMYB 1CEJA 4JZFL 3C9AC 3N8ZA 4OTYA 1XDTR 1ATAA 1YGCL 3OLTA 1MOXC 1IQFL 2P94L 3HO3A 1RFNB 1JV2B 1G2LB 1OB1C 3H5CB 1HCGB 4D0FA 1CQEA 1PFXL 3LN1A 2W2NE 2VJ3A 4RRWA 3M37L 3KQEL 2WPKE 4NG9L 1SZBA 3LTGD 3OLUA 2WYGB 5L2YL 2KL7A 4Z6AL 1HREA 2RA0L 2TGFA 1APOA 3IITB 1UZKA 2MHPA 5E8DA 1IQLL 2BOUA 2XBXL 1FSBA 1UZPA 3LC5B 1PGEA 4JYVL 1FE2A 2YGOA 1EPHA 3Q7DA 2YGPA 4JZEL 1N7DA 3CS7L 2AYLA 1K37A 4XBMA 2W2QE 1FFMA 1DDXA 1NFUB 1ATDA 3HO5A 4JYUL 4X8SL 1IP0A 3N8YA 2GD4A 5JW1A 1YUGA 2DDUA 3TZIA 1F0RB 2FD6A 2P3FL 1IQHL 5IKTA 1EQGA 4TGFA 3TK5B 4ZH8B 5COXA 3NTGA 5IKVA 3F1SB 1G1QA 4D90A 4JZDL 4AQTA 2BQ6A 5F19A 2WPHE 6COXA 1EPJA 2K2TA 3MDLA 2UWPB 2H9EL 3TK6B 2JKHL 2I9BA 2VWNL 2WPLE 2Y81B 3LTFB 1NPEB 2WG3C 3KRKA 2CJIB 3CENL 3QH0A 2D1JB 2F9BL 3PGHA 3QMOA 1NQLB 3HO4A 3GCXE 1W7XL 3FCSB 1CX2A 3ENSA 3QCWA 2M74A 1TOZA 4ZAEB 1BF9A 1XKAL 1I0UA 1HT8A 3LN0A 2VVVL 1P0SL 1J9CL 3HPTA 2I9AA 2RHPA 4X8UL 1DVAL 4BXWA 3KQBL 2P16L 1JBUL 1EMNA 3TH3L 2XBVL 1C5MF 4PH9A 2WG4B 4C16A 1IQIL 1NT0A 1IQJL 5KN5C 1HJ7A 2K2SB 1Z6CA 3U7UG 1U67A 1TLEA 3F6UL 2FLRL 5F1AA 1N1IA 1YO8A 3SW2A 3HS7A 4Y6DB 1V3XB 2BOHA 4BDWA 1APQA 5CISA 4BTTA 1HT5A 3BT1A 2OYEP 3FBYA 3SOVA 1EPIA 4X8TL 1ATBA 4ISIL 5JBBE 3GCWE
chains in the Genus database with same CATH superfamily
1NFYB 2WPME 2VWLL 1FAXL 4RRXA 1G1SA 2Y5FL 4G1MB 3ZYGA 1PXXA 2BOKL 1WHFA 2FZZL 2BQWA 1IQEL 3FFGL 1MQ6L 5EGMB 4OTJA 1WHEA 2XC5L 1O5DL 3RR3A 1F0SB 3NJPC 5JB8E 3GISX 2KNIA 4Z0KB 1LPGA 1FAKL 4ZXYL 1KLOA 1G1TA 4Z0LA 2BOXA 2Y82B 4ISHL 3LIWB 5KIRA 1CVWL 3TGFA 2WYJB 1AUTL 1WU1B 3P5BL 3M36L 1KLJL 4ZXXL 3R05A 2EI8B 2Y5GL 1EZQB 2WFTA 4YT6L 3N8WB 1X7AL 5JBCE 3KQCL 5L30L 5JVYA 2WPIE 1KSNB 2VVCK 3N8VA 2BT8A 3V65B 2PHBB 4RUTA 1L3YA 2XBWL 3U73A 4MMZB 2NPRA 3MQEA 2W2PE 4ZHAB 3NT1A 1EMOA 4Y7AB 3N8XA 3BPSE 1URKA 4FM5A 4MMXB 4Y71B 2VWOL 1EAIC 4CUEA 2BT7A 2BSFA 2Y7XB 1EPGA 2WPJE 3ELAL 1NZIA 4E1GA 1FJSL 4LORA 2RNLA 2UWOB 1IGXA 2FLGA 3SOBB 3KCGL 3N8WA 2XC0L 4BTIA 1ZAQA 4RRZA 1G2MB 1HAEA 2MGPA 2P3FN 1Z6EL 3DEMA 5L2ZL 2VH0B 1XKBA 2BO2A 2P93L 2Y7ZB 4LMFA 1M1XB 3ZYJB 4CUFA 1HZ8A 2BMGA 4RS0A 1IQML 3CFWA 1IVOC 2VVUL 2KB9A 1P9JA 4O02B 1NFWB 4M11A 2UWLB 2W3IB 2HOXA 2VWMK 1CCVA 1IQKL 1CCFA 3IJEB 4NGAL 2P26A 5K0HB 3KQDL 1YUKB 3N8YB 5JVZA 1HRFA 1F7MA 2W26B 4A94C 5I46L 1DIYA 2XBYL 3KK6A 1G1RA 1NFXB 2ADXA 2Y80B 2P28B 4YT7L 4YZUB 3V64C 4GU4A 1HX2A 5IKRA 2MGRA 2W3KB 1QFKL 3ASIA 2BQ7A 2EI6B 2J38B 2XC4L 4Y79B 3LC3B 1JL9A 3KL6B 4BXSA 2VH6B 1LPZA 3LAQA 4X8VL 1A3PA 2WZPP 1F7EA 1KIGL 1EGFA 5IKQA 1MQ5L 1TPGA 2BZ6L 1DX5I 1U8CB 2Y5HL 4BTUA 5FDQA 1DQBA 2J95B 4NA9L 2P95L 2W2OE 1Q4GA 2PR3B 2B7DL 2G00L 2Y38A 1ATEA 1XFEA 4COXA 4A7IA 4D0EA 3K9XA 4GU3A 5JB9E 4CUDA 2WFXB 3POYA 4XL1A 1UZQA 4XLWA 1K36A 2W2ME 2J2UB 1LMJA 3NTBA 1CVUA 1IQGL 1LPKA 2P3TA 1GK5A 1LQDA 1KKEA 1UZJA 1FF7A 2Q1JB 1B9WA 3ZYIB 1IJQA 4RRYA 1L5GB 4CSYA 5CKMA 4BDXA 3BT2A 1IGZA 5JBAE 2P3UA 4O1ZA 4Y76B 4M10A 3EGFA 5CKQA 1PRHA 3SOQA 2EI7B 3HS5A 1ADXA 1V1HA 1LK9A 1KLIL 2OYUP 2FLBL 3CA7A 1EQHA 1IQNL 2PUQL 3HS6A 5CKNA 2KV4A 1YUFA 3Q3KB 1W8BL 4Y7BB 1QIUA 1IOXA 2J4IB 1IOEL 1HAFA 3TBDA 1EBVA 2W86A 2J94B 2J34B 1COUA 1PTHA 4MMYB 1CEJA 4JZFL 3C9AC 3N8ZA 4OTYA 1XDTR 1ATAA 1YGCL 3OLTA 1MOXC 1IQFL 2P94L 3HO3A 1RFNB 1JV2B 1G2LB 1OB1C 3H5CB 1HCGB 4D0FA 1CQEA 1PFXL 3LN1A 2W2NE 2VJ3A 2YGQA 4RRWA 3M37L 3KQEL 2WPKE 4NG9L 1SZBA 3LTGD 3OLUA 2WYGB 5L2YL 2KL7A 3S6XA 4Z6AL 1HREA 2RA0L 2TGFA 1APOA 3IITB 1UZKA 2MHPA 5E8DA 1IQLL 2BOUA 2XBXL 1FSBA 1UZPA 3LC5B 1PGEA 4JYVL 1FE2A 2YGOA 1EPHA 3Q7DA 2YGPA 4JZEL 1N7DA 3CS7L 2AYLA 1K37A 4XBMA 2W2QE 1FFMA 1DDXA 1NFUB 1ATDA 3HO5A 4JYUL 4X8SL 1IP0A 3N8YA 2GD4A 5JW1A 1YUGA 2DDUA 3TZIA 1F0RB 2HORA 2FD6A 2P3FL 1IQHL 5IKTA 1V1IA 1EQGA 4TGFA 3TK5B 4ZH8B 2H9EC 3NTGA 5COXA 5IKVA 3F1SB 1G1QA 4D90A 4JZDL 4AQTA 2BQ6A 5F19A 2WPHE 2VRSA 6COXA 1EPJA 2K2TA 3MDLA 2UWPB 2H9EL 3TK6B 2JKHL 2I9BA 2VWNL 2WPLE 2Y81B 3LTFB 1NPEB 2WG3C 3KRKA 2CJIB 3CENL 3QH0A 2D1JB 2F9BL 3PGHA 3QMOA 1NQLB 3HO4A 3GCXE 1W7XL 3FCSB 1CX2A 3ENSA 3QCWA 2M74A 1TOZA 4ZAEB 1BF9A 1XKAL 2JJLA 1I0UA 1HT8A 3LN0A 2VVVL 1P0SL 1J9CL 3HPTA 2I9AA 2RHPA 4X8UL 1DVAL 4BXWA 3KQBL 2P16L 1JBUL 1EMNA 3TH3L 2XBVL 1C5MF 4PH9A 2WG4B 4C16A 1IQIL 1NT0A 1IQJL 5KN5C 1HJ7A 2K2SB 1Z6CA 3U7UG 1U67A 1TLEA 3F6UL 2FLRL 1LMMA 5F1AA 1N1IA 1YO8A 3SW2A 3HS7A 4Y6DB 1V3XB 2BOHA 4BDWA 1APQA 5CISA 4BTTA 1HT5A 3BT1A 2OYEP 3FBYA 3SOVA 1EPIA 4X8TL 1ATBA 4ISIL 5JBBE 3GCWE
chains in the Genus database with same CATH topology
1NFYB 2WPME 2VWLL 1FAXL 4RRXA 1G1SA 2Y5FL 4G1MB 3ZYGA 1PXXA 2BOKL 1WHFA 2FZZL 2BQWA 1IQEL 3FFGL 1MQ6L 5EGMB 4OTJA 1WHEA 2XC5L 1O5DL 3RR3A 1F0SB 3NJPC 5JB8E 3GISX 2KNIA 4Z0KB 1LPGA 1FAKL 4ZXYL 1KLOA 1G1TA 4Z0LA 2BOXA 2Y82B 4ISHL 3LIWB 5KIRA 1CVWL 3TGFA 2WYJB 1AUTL 1WU1B 3P5BL 3M36L 1KLJL 4ZXXL 3R05A 2EI8B 2Y5GL 1EZQB 2WFTA 4YT6L 3N8WB 1X7AL 5JBCE 3KQCL 5L30L 5JVYA 2WPIE 1KSNB 2VVCK 3N8VA 3V65B 2PHBB 4RUTA 1L3YA 2XBWL 3U73A 4MMZB 2NPRA 3MQEA 2W2PE 4ZHAB 3NT1A 1EMOA 4Y7AB 3N8XA 3BPSE 1URKA 4FM5A 4MMXB 4Y71B 2VWOL 1EAIC 4CUEA 2Y7XB 1EPGA 2WPJE 3ELAL 1NZIA 4E1GA 1FJSL 4LORA 2RNLA 2UWOB 1IGXA 2FLGA 3SOBB 3KCGL 3N8WA 2XC0L 4BTIA 1ZAQA 4RRZA 1G2MB 1HAEA 2MGPA 2P3FN 1Z6EL 3DEMA 5L2ZL 2VH0B 1XKBA 2BO2A 2P93L 2Y7ZB 4LMFA 1M1XB 3ZYJB 4CUFA 1HZ8A 2BMGA 4RS0A 1IQML 3CFWA 1IVOC 2VVUL 2KB9A 1P9JA 4O02B 1NFWB 4M11A 2UWLB 2W3IB 2VWMK 1CCVA 1IQKL 1CCFA 3IJEB 4NGAL 2P26A 5K0HB 3KQDL 1YUKB 3N8YB 5JVZA 1HRFA 1F7MA 2W26B 4A94C 5I46L 1DIYA 2XBYL 3KK6A 1G1RA 1NFXB 2ADXA 2Y80B 2P28B 4YT7L 4YZUB 3V64C 1HX2A 5IKRA 2MGRA 2W3KB 1QFKL 3ASIA 2BQ7A 2EI6B 2J38B 2XC4L 4Y79B 3LC3B 1JL9A 3KL6B 4BXSA 2VH6B 1LPZA 3LAQA 4X8VL 1A3PA 2WZPP 1F7EA 1KIGL 1EGFA 5IKQA 1MQ5L 1TPGA 2BZ6L 1DX5I 1U8CB 2Y5HL 4BTUA 5FDQA 1DQBA 2J95B 4NA9L 2P95L 2W2OE 1Q4GA 2PR3B 2B7DL 2G00L 2Y38A 1ATEA 1XFEA 4COXA 4A7IA 4D0EA 3K9XA 5JB9E 4CUDA 2WFXB 3POYA 4XL1A 1UZQA 4XLWA 1K36A 2W2ME 2J2UB 1LMJA 3NTBA 1CVUA 1IQGL 1LPKA 2P3TA 1GK5A 1LQDA 1UZJA 1FF7A 2Q1JB 1B9WA 3ZYIB 1IJQA 4RRYA 1L5GB 4CSYA 5CKMA 4BDXA 3BT2A 1IGZA 5JBAE 2P3UA 4O1ZA 4Y76B 4M10A 3EGFA 5CKQA 1PRHA 3SOQA 2EI7B 3HS5A 1ADXA 1KLIL 2OYUP 2FLBL 3CA7A 1EQHA 1IQNL 2PUQL 3HS6A 5CKNA 2KV4A 1YUFA 3Q3KB 1W8BL 4Y7BB 1IOXA 2J4IB 1IOEL 1HAFA 3TBDA 1EBVA 2W86A 2J94B 2J34B 1COUA 1PTHA 4MMYB 1CEJA 4JZFL 3C9AC 3N8ZA 4OTYA 1XDTR 1ATAA 1YGCL 3OLTA 1MOXC 1IQFL 2P94L 3HO3A 1RFNB 1JV2B 1G2LB 1OB1C 3H5CB 1HCGB 4D0FA 1CQEA 1PFXL 3LN1A 2W2NE 2VJ3A 2YGQA 4RRWA 3M37L 3KQEL 2WPKE 4NG9L 1SZBA 3LTGD 3OLUA 2WYGB 5L2YL 2KL7A 3S6XA 4Z6AL 1HREA 2RA0L 2TGFA 1APOA 3IITB 1UZKA 2MHPA 5E8DA 1IQLL 2BOUA 2XBXL 1FSBA 1UZPA 3LC5B 1PGEA 4JYVL 1FE2A 2YGOA 1EPHA 3Q7DA 2YGPA 4JZEL 1N7DA 3CS7L 2AYLA 1K37A 4XBMA 2W2QE 1FFMA 1DDXA 1NFUB 1ATDA 3HO5A 4JYUL 4X8SL 1IP0A 3N8YA 2GD4A 5JW1A 1YUGA 2DDUA 3TZIA 1F0RB 2FD6A 2P3FL 1IQHL 5IKTA 1EQGA 4TGFA 3TK5B 4ZH8B 2H9EC 3NTGA 5COXA 5IKVA 3F1SB 1G1QA 4D90A 4JZDL 4AQTA 2BQ6A 5F19A 2WPHE 6COXA 1EPJA 2K2TA 3MDLA 2UWPB 2H9EL 3TK6B 2JKHL 2I9BA 2VWNL 2WPLE 2Y81B 3LTFB 1NPEB 2WG3C 3KRKA 2CJIB 3CENL 3QH0A 2D1JB 2F9BL 3PGHA 3QMOA 1NQLB 3HO4A 3GCXE 1W7XL 3FCSB 1CX2A 3ENSA 3QCWA 2M74A 1TOZA 4ZAEB 1BF9A 1XKAL 1I0UA 1HT8A 3LN0A 2VVVL 1P0SL 1J9CL 3HPTA 2I9AA 2RHPA 4X8UL 1DVAL 4BXWA 3KQBL 2P16L 1JBUL 1EMNA 3TH3L 2XBVL 1C5MF 4PH9A 2WG4B 4C16A 1IQIL 1NT0A 1IQJL 5KN5C 1HJ7A 2K2SB 1Z6CA 3U7UG 1U67A 1TLEA 3F6UL 2FLRL 1LMMA 5F1AA 1N1IA 1YO8A 3SW2A 3HS7A 4Y6DB 1V3XB 2BOHA 4BDWA 1APQA 5CISA 4BTTA 1HT5A 3BT1A 2OYEP 3FBYA 3SOVA 1EPIA 4X8TL 1ATBA 4ISIL 5JBBE 3GCWE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NFY B;  2WPM E;  2VWL L;  1FAX L;  4RRX A;  1G1S A;  2Y5F L;  4G1M B;  3ZYG A;  1PXX A;  2BOK L;  1WHF A;  2FZZ L;  2BQW A;  1IQE L;  3FFG L;  1MQ6 L;  5EGM B;  4OTJ A;  1WHE A;  2XC5 L;  1O5D L;  3RR3 A;  1F0S B;  3NJP C;  5JB8 E;  3GIS X;  4Z0K B;  1LPG A;  1FAK L;  4ZXY L;  1KLO A;  1G1T A;  4Z0L A;  2BOX A;  2Y82 B;  4ISH L;  3LIW B;  5KIR A;  1CVW L;  3TGF A;  2WYJ B;  1AUT L;  1WU1 B;  3P5B L;  3M36 L;  1KLJ L;  4ZXX L;  3R05 A;  2EI8 B;  2Y5G L;  1EZQ B;  2WFT A;  4YT6 L;  3N8W B;  1X7A L;  5JBC E;  3KQC L;  5L30 L;  5JVY A;  2WPI E;  1KSN B;  2VVC K;  3N8V A;  3V65 B;  2PHB B;  4RUT A;  1L3Y A;  2XBW L;  3U73 A;  4MMZ B;  2NPR A;  3MQE A;  2W2P E;  4ZHA B;  3NT1 A;  1EMO A;  4Y7A B;  3N8X A;  3BPS E;  1URK A;  4FM5 A;  4MMX B;  4Y71 B;  2VWO L;  1EAI C;  4CUE A;  2Y7X B;  1EPG A;  2WPJ E;  3ELA L;  1NZI A;  4E1G A;  1FJS L;  4LOR A;  2RNL A;  2UWO B;  1IGX A;  2FLG A;  3SOB B;  3KCG L;  3N8W A;  2XC0 L;  4BTI A;  1ZAQ A;  4RRZ A;  1G2M B;  1HAE A;  2MGP A;  2P3F N;  1Z6E L;  3DEM A;  5L2Z L;  2VH0 B;  1XKB A;  2BO2 A;  2P93 L;  2Y7Z B;  4LMF A;  1M1X B;  3ZYJ B;  4CUF A;  1HZ8 A;  2BMG A;  4RS0 A;  1IQM L;  3CFW A;  1IVO C;  2VVU L;  2KB9 A;  1P9J A;  4O02 B;  1NFW B;  4M11 A;  2UWL B;  2W3I B;  2VWM K;  1CCV A;  1IQK L;  1CCF A;  3IJE B;  4NGA L;  2P26 A;  5K0H B;  3KQD L;  1YUK B;  3N8Y B;  5JVZ A;  1HRF A;  1F7M A;  2W26 B;  5I46 L;  1DIY A;  2XBY L;  3KK6 A;  1G1R A;  1NFX B;  2ADX A;  2Y80 B;  2P28 B;  4YT7 L;  4YZU B;  3V64 C;  1HX2 A;  5IKR A;  2MGR A;  2W3K B;  1QFK L;  3ASI A;  2BQ7 A;  2EI6 B;  2J38 B;  2XC4 L;  4Y79 B;  3LC3 B;  1JL9 A;  3KL6 B;  4BXS A;  2VH6 B;  1LPZ A;  3LAQ A;  4X8V L;  1A3P A;  1F7E A;  1KIG L;  1EGF A;  5IKQ A;  1MQ5 L;  1TPG A;  2BZ6 L;  1DX5 I;  1U8C B;  2Y5H L;  4BTU A;  5FDQ A;  1DQB A;  2J95 B;  4NA9 L;  2P95 L;  2W2O E;  1Q4G A;  2PR3 B;  2B7D L;  2G00 L;  2Y38 A;  1ATE A;  1XFE A;  4COX A;  4A7I A;  4D0E A;  3K9X A;  5JB9 E;  4CUD A;  2WFX B;  3POY A;  4XL1 A;  1UZQ A;  4XLW A;  1K36 A;  2W2M E;  2J2U B;  1LMJ A;  3NTB A;  1CVU A;  1IQG L;  1LPK A;  2P3T A;  1GK5 A;  1LQD A;  1UZJ A;  1FF7 A;  2Q1J B;  1B9W A;  3ZYI B;  1IJQ A;  4RRY A;  1L5G B;  4CSY A;  5CKM A;  4BDX A;  3BT2 A;  1IGZ A;  5JBA E;  2P3U A;  4O1Z A;  4Y76 B;  4M10 A;  3EGF A;  5CKQ A;  1PRH A;  3SOQ A;  2EI7 B;  3HS5 A;  1ADX A;  1KLI L;  2OYU P;  2FLB L;  3CA7 A;  1EQH A;  1IQN L;  2PUQ L;  3HS6 A;  5CKN A;  2KV4 A;  1YUF A;  3Q3K B;  1W8B L;  4Y7B B;  1IOX A;  2J4I B;  1IOE L;  1HAF A;  3TBD A;  1EBV A;  2W86 A;  2J94 B;  2J34 B;  1COU A;  1PTH A;  4MMY B;  1CEJ A;  4JZF L;  3C9A C;  3N8Z A;  4OTY A;  1XDT R;  1ATA A;  1YGC L;  3OLT A;  1MOX C;  1IQF L;  2P94 L;  3HO3 A;  1RFN B;  1JV2 B;  1G2L B;  1OB1 C;  3H5C B;  1HCG B;  4D0F A;  1CQE A;  1PFX L;  3LN1 A;  2W2N E;  2VJ3 A;  4RRW A;  3M37 L;  3KQE L;  2WPK E;  4NG9 L;  1SZB A;  3LTG D;  3OLU A;  2WYG B;  5L2Y L;  2KL7 A;  4Z6A L;  1HRE A;  2RA0 L;  2TGF A;  1APO A;  3IIT B;  1UZK A;  2MHP A;  5E8D A;  1IQL L;  2BOU A;  2XBX L;  1FSB A;  1UZP A;  3LC5 B;  1PGE A;  4JYV L;  1FE2 A;  2YGO A;  1EPH A;  3Q7D A;  2YGP A;  4JZE L;  1N7D A;  3CS7 L;  2AYL A;  1K37 A;  4XBM A;  2W2Q E;  1FFM A;  1DDX A;  1NFU B;  1ATD A;  3HO5 A;  4JYU L;  4X8S L;  1IP0 A;  3N8Y A;  2GD4 A;  5JW1 A;  1YUG A;  2DDU A;  3TZI A;  1F0R B;  2FD6 A;  2P3F L;  1IQH L;  5IKT A;  1EQG A;  4TGF A;  3TK5 B;  4ZH8 B;  5COX A;  3NTG A;  5IKV A;  3F1S B;  1G1Q A;  4D90 A;  4JZD L;  4AQT A;  2BQ6 A;  5F19 A;  2WPH E;  6COX A;  1EPJ A;  2K2T A;  3MDL A;  2UWP B;  2H9E L;  3TK6 B;  2JKH L;  2I9B A;  2VWN L;  2WPL E;  2Y81 B;  3LTF B;  1NPE B;  2WG3 C;  3KRK A;  2CJI B;  3CEN L;  3QH0 A;  2D1J B;  2F9B L;  3PGH A;  3QMO A;  1NQL B;  3HO4 A;  3GCX E;  1W7X L;  3FCS B;  1CX2 A;  3ENS A;  3QCW A;  2M74 A;  1TOZ A;  4ZAE B;  1BF9 A;  1XKA L;  1I0U A;  1HT8 A;  3LN0 A;  2VVV L;  1P0S L;  1J9C L;  3HPT A;  2I9A A;  2RHP A;  4X8U L;  1DVA L;  4BXW A;  3KQB L;  2P16 L;  1JBU L;  1EMN A;  3TH3 L;  2XBV L;  1C5M F;  4PH9 A;  2WG4 B;  4C16 A;  1IQI L;  1NT0 A;  1IQJ L;  5KN5 C;  1HJ7 A;  2K2S B;  1Z6C A;  3U7U G;  1U67 A;  1TLE A;  3F6U L;  2FLR L;  5F1A A;  1N1I A;  1YO8 A;  3SW2 A;  3HS7 A;  4Y6D B;  1V3X B;  2BOH A;  4BDW A;  1APQ A;  5CIS A;  4BTT A;  1HT5 A;  3BT1 A;  2OYE P;  3FBY A;  3SOV A;  1EPI A;  4X8T L;  1ATB A;  4ISI L;  5JBB E;  3GCW E; 
#chains in the Genus database with same CATH topology
 1NFY B;  2WPM E;  2VWL L;  1FAX L;  4RRX A;  1G1S A;  2Y5F L;  4G1M B;  3ZYG A;  1PXX A;  2BOK L;  1WHF A;  2FZZ L;  2BQW A;  1IQE L;  3FFG L;  1MQ6 L;  5EGM B;  4OTJ A;  1WHE A;  2XC5 L;  1O5D L;  3RR3 A;  1F0S B;  3NJP C;  5JB8 E;  3GIS X;  2KNI A;  4Z0K B;  1LPG A;  1FAK L;  4ZXY L;  1KLO A;  1G1T A;  4Z0L A;  2BOX A;  2Y82 B;  4ISH L;  3LIW B;  5KIR A;  1CVW L;  3TGF A;  2WYJ B;  1AUT L;  1WU1 B;  3P5B L;  3M36 L;  1KLJ L;  4ZXX L;  3R05 A;  2EI8 B;  2Y5G L;  1EZQ B;  2WFT A;  4YT6 L;  3N8W B;  1X7A L;  5JBC E;  3KQC L;  5L30 L;  5JVY A;  2WPI E;  1KSN B;  2VVC K;  3N8V A;  2BT8 A;  3V65 B;  2PHB B;  4RUT A;  1L3Y A;  2XBW L;  3U73 A;  4MMZ B;  2NPR A;  3MQE A;  2W2P E;  4ZHA B;  3NT1 A;  1EMO A;  4Y7A B;  3N8X A;  3BPS E;  1URK A;  4FM5 A;  4MMX B;  4Y71 B;  2VWO L;  1EAI C;  4CUE A;  2BT7 A;  2BSF A;  2Y7X B;  1EPG A;  2WPJ E;  3ELA L;  1NZI A;  4E1G A;  1FJS L;  4LOR A;  2RNL A;  2UWO B;  1IGX A;  2FLG A;  3SOB B;  3KCG L;  3N8W A;  2XC0 L;  4BTI A;  1ZAQ A;  4RRZ A;  1G2M B;  1HAE A;  2MGP A;  2P3F N;  1Z6E L;  3DEM A;  5L2Z L;  2VH0 B;  1XKB A;  2BO2 A;  2P93 L;  2Y7Z B;  4LMF A;  1M1X B;  3ZYJ B;  4CUF A;  1HZ8 A;  2BMG A;  4RS0 A;  1IQM L;  3CFW A;  1IVO C;  2VVU L;  2KB9 A;  1P9J A;  4O02 B;  1NFW B;  4M11 A;  2UWL B;  2W3I B;  2HOX A;  2VWM K;  1CCV A;  1IQK L;  1CCF A;  3IJE B;  4NGA L;  2P26 A;  5K0H B;  3KQD L;  1YUK B;  3N8Y B;  5JVZ A;  1HRF A;  1F7M A;  2W26 B;  4A94 C;  5I46 L;  1DIY A;  2XBY L;  3KK6 A;  1G1R A;  1NFX B;  2ADX A;  2Y80 B;  2P28 B;  4YT7 L;  4YZU B;  3V64 C;  4GU4 A;  1HX2 A;  5IKR A;  2MGR A;  2W3K B;  1QFK L;  3ASI A;  2BQ7 A;  2EI6 B;  2J38 B;  2XC4 L;  4Y79 B;  3LC3 B;  1JL9 A;  3KL6 B;  4BXS A;  2VH6 B;  1LPZ A;  3LAQ A;  4X8V L;  1A3P A;  2WZP P;  1F7E A;  1KIG L;  1EGF A;  5IKQ A;  1MQ5 L;  1TPG A;  2BZ6 L;  1DX5 I;  1U8C B;  2Y5H L;  4BTU A;  5FDQ A;  1DQB A;  2J95 B;  4NA9 L;  2P95 L;  2W2O E;  1Q4G A;  2PR3 B;  2B7D L;  2G00 L;  2Y38 A;  1ATE A;  1XFE A;  4COX A;  4A7I A;  4D0E A;  3K9X A;  4GU3 A;  5JB9 E;  4CUD A;  2WFX B;  3POY A;  4XL1 A;  1UZQ A;  4XLW A;  1K36 A;  2W2M E;  2J2U B;  1LMJ A;  3NTB A;  1CVU A;  1IQG L;  1LPK A;  2P3T A;  1GK5 A;  1LQD A;  1KKE A;  1UZJ A;  1FF7 A;  2Q1J B;  1B9W A;  3ZYI B;  1IJQ A;  4RRY A;  1L5G B;  4CSY A;  5CKM A;  4BDX A;  3BT2 A;  1IGZ A;  5JBA E;  2P3U A;  4O1Z A;  4Y76 B;  4M10 A;  3EGF A;  5CKQ A;  1PRH A;  3SOQ A;  2EI7 B;  3HS5 A;  1ADX A;  1V1H A;  1LK9 A;  1KLI L;  2OYU P;  2FLB L;  3CA7 A;  1EQH A;  1IQN L;  2PUQ L;  3HS6 A;  5CKN A;  2KV4 A;  1YUF A;  3Q3K B;  1W8B L;  4Y7B B;  1QIU A;  1IOX A;  2J4I B;  1IOE L;  1HAF A;  3TBD A;  1EBV A;  2W86 A;  2J94 B;  2J34 B;  1COU A;  1PTH A;  4MMY B;  1CEJ A;  4JZF L;  3C9A C;  3N8Z A;  4OTY A;  1XDT R;  1ATA A;  1YGC L;  3OLT A;  1MOX C;  1IQF L;  2P94 L;  3HO3 A;  1RFN B;  1JV2 B;  1G2L B;  1OB1 C;  3H5C B;  1HCG B;  4D0F A;  1CQE A;  1PFX L;  3LN1 A;  2W2N E;  2VJ3 A;  2YGQ A;  4RRW A;  3M37 L;  3KQE L;  2WPK E;  4NG9 L;  1SZB A;  3LTG D;  3OLU A;  2WYG B;  5L2Y L;  2KL7 A;  3S6X A;  4Z6A L;  1HRE A;  2RA0 L;  2TGF A;  1APO A;  3IIT B;  1UZK A;  2MHP A;  5E8D A;  1IQL L;  2BOU A;  2XBX L;  1FSB A;  1UZP A;  3LC5 B;  1PGE A;  4JYV L;  1FE2 A;  2YGO A;  1EPH A;  3Q7D A;  2YGP A;  4JZE L;  1N7D A;  3CS7 L;  2AYL A;  1K37 A;  4XBM A;  2W2Q E;  1FFM A;  1DDX A;  1NFU B;  1ATD A;  3HO5 A;  4JYU L;  4X8S L;  1IP0 A;  3N8Y A;  2GD4 A;  5JW1 A;  1YUG A;  2DDU A;  3TZI A;  1F0R B;  2HOR A;  2FD6 A;  2P3F L;  1IQH L;  5IKT A;  1V1I A;  1EQG A;  4TGF A;  3TK5 B;  4ZH8 B;  2H9E C;  3NTG A;  5COX A;  5IKV A;  3F1S B;  1G1Q A;  4D90 A;  4JZD L;  4AQT A;  2BQ6 A;  5F19 A;  2WPH E;  2VRS A;  6COX A;  1EPJ A;  2K2T A;  3MDL A;  2UWP B;  2H9E L;  3TK6 B;  2JKH L;  2I9B A;  2VWN L;  2WPL E;  2Y81 B;  3LTF B;  1NPE B;  2WG3 C;  3KRK A;  2CJI B;  3CEN L;  3QH0 A;  2D1J B;  2F9B L;  3PGH A;  3QMO A;  1NQL B;  3HO4 A;  3GCX E;  1W7X L;  3FCS B;  1CX2 A;  3ENS A;  3QCW A;  2M74 A;  1TOZ A;  4ZAE B;  1BF9 A;  1XKA L;  2JJL A;  1I0U A;  1HT8 A;  3LN0 A;  2VVV L;  1P0S L;  1J9C L;  3HPT A;  2I9A A;  2RHP A;  4X8U L;  1DVA L;  4BXW A;  3KQB L;  2P16 L;  1JBU L;  1EMN A;  3TH3 L;  2XBV L;  1C5M F;  4PH9 A;  2WG4 B;  4C16 A;  1IQI L;  1NT0 A;  1IQJ L;  5KN5 C;  1HJ7 A;  2K2S B;  1Z6C A;  3U7U G;  1U67 A;  1TLE A;  3F6U L;  2FLR L;  1LMM A;  5F1A A;  1N1I A;  1YO8 A;  3SW2 A;  3HS7 A;  4Y6D B;  1V3X B;  2BOH A;  4BDW A;  1APQ A;  5CIS A;  4BTT A;  1HT5 A;  3BT1 A;  2OYE P;  3FBY A;  3SOV A;  1EPI A;  4X8T L;  1ATB A;  4ISI L;  5JBB E;  3GCW E; 
#chains in the Genus database with same CATH homology
 1NFY B;  2WPM E;  2VWL L;  1FAX L;  4RRX A;  1G1S A;  2Y5F L;  4G1M B;  3ZYG A;  1PXX A;  2BOK L;  1WHF A;  2FZZ L;  2BQW A;  1IQE L;  3FFG L;  1MQ6 L;  5EGM B;  4OTJ A;  1WHE A;  2XC5 L;  1O5D L;  3RR3 A;  1F0S B;  3NJP C;  5JB8 E;  3GIS X;  2KNI A;  4Z0K B;  1LPG A;  1FAK L;  4ZXY L;  1KLO A;  1G1T A;  4Z0L A;  2BOX A;  2Y82 B;  4ISH L;  3LIW B;  5KIR A;  1CVW L;  3TGF A;  2WYJ B;  1AUT L;  1WU1 B;  3P5B L;  3M36 L;  1KLJ L;  4ZXX L;  3R05 A;  2EI8 B;  2Y5G L;  1EZQ B;  2WFT A;  4YT6 L;  3N8W B;  1X7A L;  5JBC E;  3KQC L;  5L30 L;  5JVY A;  2WPI E;  1KSN B;  2VVC K;  3N8V A;  3V65 B;  2PHB B;  4RUT A;  1L3Y A;  2XBW L;  3U73 A;  4MMZ B;  2NPR A;  3MQE A;  2W2P E;  4ZHA B;  3NT1 A;  1EMO A;  4Y7A B;  3N8X A;  3BPS E;  1URK A;  4FM5 A;  4MMX B;  4Y71 B;  2VWO L;  1EAI C;  4CUE A;  2Y7X B;  1EPG A;  2WPJ E;  3ELA L;  1NZI A;  4E1G A;  1FJS L;  4LOR A;  2RNL A;  2UWO B;  1IGX A;  2FLG A;  3SOB B;  3KCG L;  3N8W A;  2XC0 L;  4BTI A;  1ZAQ A;  4RRZ A;  1G2M B;  1HAE A;  2MGP A;  2P3F N;  1Z6E L;  3DEM A;  5L2Z L;  2VH0 B;  1XKB A;  2BO2 A;  2P93 L;  2Y7Z B;  4LMF A;  1M1X B;  3ZYJ B;  4CUF A;  1HZ8 A;  2BMG A;  4RS0 A;  1IQM L;  3CFW A;  1IVO C;  2VVU L;  2KB9 A;  1P9J A;  4O02 B;  1NFW B;  4M11 A;  2UWL B;  2W3I B;  2VWM K;  1CCV A;  1IQK L;  1CCF A;  3IJE B;  4NGA L;  2P26 A;  5K0H B;  3KQD L;  1YUK B;  3N8Y B;  5JVZ A;  1HRF A;  1F7M A;  2W26 B;  4A94 C;  5I46 L;  1DIY A;  2XBY L;  3KK6 A;  1G1R A;  1NFX B;  2ADX A;  2Y80 B;  2P28 B;  4YT7 L;  4YZU B;  3V64 C;  1HX2 A;  5IKR A;  2MGR A;  2W3K B;  1QFK L;  3ASI A;  2BQ7 A;  2EI6 B;  2J38 B;  2XC4 L;  4Y79 B;  3LC3 B;  1JL9 A;  3KL6 B;  4BXS A;  2VH6 B;  1LPZ A;  3LAQ A;  4X8V L;  1A3P A;  2WZP P;  1F7E A;  1KIG L;  1EGF A;  5IKQ A;  1MQ5 L;  1TPG A;  2BZ6 L;  1DX5 I;  1U8C B;  2Y5H L;  4BTU A;  5FDQ A;  1DQB A;  2J95 B;  4NA9 L;  2P95 L;  2W2O E;  1Q4G A;  2PR3 B;  2B7D L;  2G00 L;  2Y38 A;  1ATE A;  1XFE A;  4COX A;  4A7I A;  4D0E A;  3K9X A;  5JB9 E;  4CUD A;  2WFX B;  3POY A;  4XL1 A;  1UZQ A;  4XLW A;  1K36 A;  2W2M E;  2J2U B;  1LMJ A;  3NTB A;  1CVU A;  1IQG L;  1LPK A;  2P3T A;  1GK5 A;  1LQD A;  1UZJ A;  1FF7 A;  2Q1J B;  1B9W A;  3ZYI B;  1IJQ A;  4RRY A;  1L5G B;  4CSY A;  5CKM A;  4BDX A;  3BT2 A;  1IGZ A;  5JBA E;  2P3U A;  4O1Z A;  4Y76 B;  4M10 A;  3EGF A;  5CKQ A;  1PRH A;  3SOQ A;  2EI7 B;  3HS5 A;  1ADX A;  1KLI L;  2OYU P;  2FLB L;  3CA7 A;  1EQH A;  1IQN L;  2PUQ L;  3HS6 A;  5CKN A;  2KV4 A;  1YUF A;  3Q3K B;  1W8B L;  4Y7B B;  1IOX A;  2J4I B;  1IOE L;  1HAF A;  3TBD A;  1EBV A;  2W86 A;  2J94 B;  2J34 B;  1COU A;  1PTH A;  4MMY B;  1CEJ A;  4JZF L;  3C9A C;  3N8Z A;  4OTY A;  1XDT R;  1ATA A;  1YGC L;  3OLT A;  1MOX C;  1IQF L;  2P94 L;  3HO3 A;  1RFN B;  1JV2 B;  1G2L B;  1OB1 C;  3H5C B;  1HCG B;  4D0F A;  1CQE A;  1PFX L;  3LN1 A;  2W2N E;  2VJ3 A;  2YGQ A;  4RRW A;  3M37 L;  3KQE L;  2WPK E;  4NG9 L;  1SZB A;  3LTG D;  3OLU A;  2WYG B;  5L2Y L;  2KL7 A;  3S6X A;  4Z6A L;  1HRE A;  2RA0 L;  2TGF A;  1APO A;  3IIT B;  1UZK A;  2MHP A;  5E8D A;  1IQL L;  2BOU A;  2XBX L;  1FSB A;  1UZP A;  3LC5 B;  1PGE A;  4JYV L;  1FE2 A;  2YGO A;  1EPH A;  3Q7D A;  2YGP A;  4JZE L;  1N7D A;  3CS7 L;  2AYL A;  1K37 A;  4XBM A;  2W2Q E;  1FFM A;  1DDX A;  1NFU B;  1ATD A;  3HO5 A;  4JYU L;  4X8S L;  1IP0 A;  3N8Y A;  2GD4 A;  5JW1 A;  1YUG A;  2DDU A;  3TZI A;  1F0R B;  2FD6 A;  2P3F L;  1IQH L;  5IKT A;  1EQG A;  4TGF A;  3TK5 B;  4ZH8 B;  2H9E C;  3NTG A;  5COX A;  5IKV A;  3F1S B;  1G1Q A;  4D90 A;  4JZD L;  4AQT A;  2BQ6 A;  5F19 A;  2WPH E;  6COX A;  1EPJ A;  2K2T A;  3MDL A;  2UWP B;  2H9E L;  3TK6 B;  2JKH L;  2I9B A;  2VWN L;  2WPL E;  2Y81 B;  3LTF B;  1NPE B;  2WG3 C;  3KRK A;  2CJI B;  3CEN L;  3QH0 A;  2D1J B;  2F9B L;  3PGH A;  3QMO A;  1NQL B;  3HO4 A;  3GCX E;  1W7X L;  3FCS B;  1CX2 A;  3ENS A;  3QCW A;  2M74 A;  1TOZ A;  4ZAE B;  1BF9 A;  1XKA L;  1I0U A;  1HT8 A;  3LN0 A;  2VVV L;  1P0S L;  1J9C L;  3HPT A;  2I9A A;  2RHP A;  4X8U L;  1DVA L;  4BXW A;  3KQB L;  2P16 L;  1JBU L;  1EMN A;  3TH3 L;  2XBV L;  1C5M F;  4PH9 A;  2WG4 B;  4C16 A;  1IQI L;  1NT0 A;  1IQJ L;  5KN5 C;  1HJ7 A;  2K2S B;  1Z6C A;  3U7U G;  1U67 A;  1TLE A;  3F6U L;  2FLR L;  1LMM A;  5F1A A;  1N1I A;  1YO8 A;  3SW2 A;  3HS7 A;  4Y6D B;  1V3X B;  2BOH A;  4BDW A;  1APQ A;  5CIS A;  4BTT A;  1HT5 A;  3BT1 A;  2OYE P;  3FBY A;  3SOV A;  1EPI A;  4X8T L;  1ATB A;  4ISI L;  5JBB E;  3GCW E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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