4YT7L

Factor viia in complex with the inhibitor 2-(2-{(r)-[(4-carbamimidoylphenyl)amino][5-ethoxy-2-fluoro-3-(propan-2-yloxy)phenyl]methyl}-1h-imidazol-4-yl)benzamide
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
57
structure length
57
Chain Sequence
QLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Design and synthesis of potent, selective phenylimidazole-based FVIIa inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Coagulation factor VII (heavy chain)
total genus 12
structure length 57
sequence length 57
ec nomenclature ec 3.4.21.21: Coagulation factor VIIa.
pdb deposition date 2015-03-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 4yt7L00
3KQCL 1OB1C 4Y79B 1YUKB 1FF7A 1TLEA 3NT1A 1PTHA 5I46L 2UWLB 2OYEP 1PRHA 1HAEA 1QFKL 2VH0B 3M36L 2WPME 2OYUP 1J9CL 5IKQA 1UZKA 1B9WA 1EMOA 1JL9A 5IKRA 3V64C 2J4IB 3P5BL 1PGEA 4RRWA 3HO5A 2KV4A 3U73A 5CISA 1IQKL 2JKHL 2P28B 3NTGA 5CKNA 4BDWA 4OTYA 4COXA 4Y6DB 5JBBE 4O1ZA 1SZBA 1M1XB 1FAXL 2BOKL 1KLIL 1NPEB 2XBWL 4JZFL 3OLTA 1NFUB 3EGFA 3NTBA 5KN5C 2P93L 1LPGA 3M37L 3LAQA 2K2SB 1APQA 1HX2A 3Q3KB 2Q1JB 4XLWA 1CEJA 1EAIC 2P95L 4NG9L 4C16A 2VWLL 2BOUA 3NJPC 1G1TA 2WYGB 1LPKA 5JBAE 2FLBL 4JYUL 1EPGA 4RS0A 4FM5A 2W2QE 4MMYB 1EBVA 1WU1B 2VVCK 4PH9A 4LORA 2YGOA 4BTTA 4RRYA 5IKVA 4LMFA 1FJSL 1DIYA 1TPGA 3IITB 1XFEA 3PGHA 4RRZA 1XDTR 1YUGA 4Y7AB 2XC5L 2CJIB 1G1RA 2RA0L 1ATAA 2P3TA 1MQ5L 2P3FL 1ATBA 1HT5A 3U7UG 3QMOA 2W86A 1NFXB 1IQML 2XBVL 3ASIA 4RRXA 2WPKE 4ISIL 2F9BL 2KB9A 1C5MF 1U67A 3BPSE 1JBUL 1A3PA 4YT7L 1LMJA 6COXA 2DDUA 3CENL 4BTUA 5COXA 1KSNB 2I9BA 4OTJA 4BXWA 3K9XA 4JZEL 1FFMA 3F1SB 1I0UA 3TZIA 3F6UL 1WHEA 1K36A 1DVAL 1G1QA 3OLUA 2WFTA 3GCWE 3SOBB 1P0SL 2W2OE 3TBDA 1YUFA 1MQ6L 5CKQA 4Y7BB 5JB8E 4G1MB 4X8UL 4ZHAB 3KQEL 1IQJL 2NPRA 1F0SB 2PUQL 2WYJB 1N7DA 1EMNA 1HJ7A 1V3XB 3CA7A 2WPLE 4AQTA 1JV2B 1LPZA 1UZPA 1KIGL 2BOHA 4YT6L 2BMGA 1BF9A 1IOXA 5FDQA 2VVVL 3SOQA 4XBMA 2BQ6A 1FAKL 1IGZA 1XKBA 4JZDL 1GK5A 2XC0L 3IJEB 3N8ZA 2WG3C 3Q7DA 2W2ME 4ZH8B 2P94L 5JW1A 5IKTA 4Y71B 2WPIE 1IQEL 2Y82B 1COUA 3LIWB 3HO4A 1RFNB 5F19A 2J94B 1APOA 4O02B 1IQIL 2XC4L 2XBXL 3LC3B 2M74A 2H9EL 1AUTL 1EGFA 1NT0A 2P26A 1HAFA 2W3KB 1HREA 3LN1A 3KL6B 1CQEA 4E1GA 3HO3A 3ZYGA 2EI8B 1DDXA 1ATDA 4CUEA 3BT1A 2UWOB 4ZXXL 1F0RB 2VH6B 2FD6A 2G00L 2VVUL 4X8TL 5L30L 5F1AA 1YO8A 4Z0KB 1EQHA 1EPHA 3TK6B 4ISHL 1IQNL 4MMXB 2BQ7A 1IJQA 1WHFA 2Y7XB 1U8CB 1L5GB 2W2NE 1URKA 3DEMA 1EZQB 3KK6A 1O5DL 1FE2A 2W26B 1NFYB 3N8XA 4ZXYL 3ENSA 3RR3A 4JYVL 1W7XL 3N8YA 5K0HB 3KQDL 4Y76B 3TK5B 2Y5FL 4RUTA 1Z6EL 4X8VL 2Y7ZB 2XBYL 1IQFL 2Y5HL 5JVZA 1DX5I 1G1SA 1TOZA 3CS7L 5CKMA 1ZAQA 4D90A 1N1IA 3N8VA 3LTFB 4Z6AL 1IP0A 1MOXC 1CVUA 3ELAL 2Y38A 3N8YB 2K2TA 3R05A 3C9AC 1EPIA 2W2PE 3QCWA 1G2LB 2PHBB 1UZQA 3V65B 1IQGL 2Y5GL 1P9JA 3MQEA 2FLRL 1IQHL 2P3UA 1CCVA 1ADXA 2D1JB 4CSYA 1DQBA 4CUDA 4M11A 2BZ6L 3FFGL 2UWPB 5L2ZL 1IVOC 1X7AL 2FZZL 5L2YL 1EPJA 4YZUB 2RNLA 2W3IB 1HZ8A 2WPJE 2Y80B 3HS7A 4NA9L 1KLOA 5JVYA 2FLGA 3ZYJB 2GD4A 5E8DA 4D0EA 2BQWA 1F7EA 4A7IA 1L3YA 4BDXA 2Y81B 1XKAL 2VWOL 2J38B 2VWMK 2PR3B 2MGRA 1YGCL 1ATEA 3MDLA 4Z0LA 3KCGL 3HPTA 1LQDA 4NGAL 3LN0A 1NFWB 2EI6B 4CUFA 3BT2A 2KL7A 2RHPA 3HS5A 3FCSB 2WPHE 4TGFA 4XL1A 1FSBA 3TH3L 3GCXE 1F7MA 2YGPA 3TGFA 3KQBL 1PXXA 3FBYA 1W8BL 5EGMB 1HT8A 2J95B 1Z6CA 3LTGD 2AYLA 5JB9E 2P16L 1CX2A 4D0FA 1NQLB 2EI7B 2I9AA 1Q4GA 5JBCE 1IGXA 2ADXA 1EQGA 1G2MB 2TGFA 1NZIA 3CFWA 2MHPA 3N8WA 1CCFA 1HRFA 1IQLL 2B7DL 2WG4B 3HS6A 1CVWL 3LC5B 3KRKA 2P3FN 4X8SL 1PFXL 3GISX 4MMZB 4ZAEB 2VWNL 2MGPA 1K37A 4M10A 3SW2A 3H5CB 2WFXB 3N8WB 2BO2A 1UZJA 3POYA 1KLJL 1IOEL 2J2UB 3SOVA 3QH0A 5KIRA 4BTIA 3ZYIB 2VJ3A 2J34B 1HCGB 4BXSA 2BOXA
chains in the Genus database with same CATH superfamily
3KQCL 1OB1C 4Y79B 1YUKB 1FF7A 1TLEA 3NT1A 1PTHA 5I46L 2UWLB 2OYEP 1PRHA 1HAEA 1QFKL 2VH0B 3M36L 2WPME 2OYUP 1J9CL 5IKQA 1UZKA 1B9WA 1EMOA 1JL9A 5IKRA 3V64C 2J4IB 3P5BL 1PGEA 4RRWA 3HO5A 2KV4A 3U73A 5CISA 1IQKL 2JKHL 2P28B 3NTGA 5CKNA 4BDWA 4OTYA 4COXA 4Y6DB 5JBBE 4O1ZA 1SZBA 1M1XB 1FAXL 2BOKL 1KLIL 1NPEB 2XBWL 4JZFL 3OLTA 1NFUB 3EGFA 3NTBA 5KN5C 2P93L 1LPGA 3M37L 3LAQA 4GU3A 2K2SB 1APQA 1HX2A 3Q3KB 2Q1JB 4XLWA 1CEJA 1EAIC 2P95L 1V1IA 4NG9L 4C16A 2VWLL 2BOUA 3NJPC 1G1TA 2WYGB 1LPKA 5JBAE 2FLBL 4JYUL 1EPGA 4RS0A 4FM5A 2W2QE 4MMYB 1EBVA 1WU1B 2VVCK 4PH9A 4LORA 2YGOA 4BTTA 4RRYA 5IKVA 4LMFA 1FJSL 1DIYA 1TPGA 3IITB 1XFEA 3PGHA 4RRZA 1XDTR 1YUGA 1QIUA 4Y7AB 2XC5L 2CJIB 2JJLA 1G1RA 2RA0L 1ATAA 2P3TA 1MQ5L 2P3FL 1ATBA 1HT5A 3U7UG 3QMOA 2W86A 1NFXB 1IQML 2XBVL 3ASIA 4RRXA 2WPKE 4ISIL 2F9BL 2KB9A 1C5MF 1U67A 3BPSE 1JBUL 1A3PA 4YT7L 1LMJA 6COXA 2DDUA 3CENL 4BTUA 5COXA 1KSNB 2I9BA 4OTJA 4BXWA 3K9XA 4JZEL 1FFMA 3F1SB 1I0UA 3TZIA 2BT8A 3F6UL 1WHEA 1K36A 1DVAL 1G1QA 3OLUA 2WFTA 3GCWE 3SOBB 1P0SL 2W2OE 3TBDA 1YUFA 1MQ6L 5CKQA 4Y7BB 5JB8E 4G1MB 4X8UL 4ZHAB 3KQEL 1IQJL 2NPRA 1F0SB 2PUQL 2WYJB 1N7DA 1EMNA 1HJ7A 1V3XB 3CA7A 2WPLE 4AQTA 1JV2B 1LPZA 1UZPA 1KIGL 2BOHA 4YT6L 2YGQA 2BMGA 1BF9A 1IOXA 5FDQA 2VVVL 3SOQA 4XBMA 2BQ6A 1FAKL 1IGZA 1XKBA 4JZDL 1GK5A 2XC0L 3IJEB 3N8ZA 2WG3C 3Q7DA 2W2ME 4ZH8B 2P94L 5JW1A 5IKTA 1KKEA 4Y71B 2WPIE 1IQEL 2Y82B 1COUA 3LIWB 3HO4A 1RFNB 5F19A 2J94B 1APOA 4O02B 1IQIL 2XC4L 2XBXL 3LC3B 2M74A 2H9EL 1AUTL 1EGFA 1NT0A 2P26A 1HAFA 2W3KB 1HREA 3LN1A 3KL6B 1CQEA 4E1GA 3HO3A 3ZYGA 2EI8B 1DDXA 1ATDA 4CUEA 3BT1A 2UWOB 4ZXXL 1F0RB 2VH6B 2FD6A 2G00L 2VVUL 4X8TL 5L30L 5F1AA 1YO8A 2VRSA 4Z0KB 1EQHA 1EPHA 3TK6B 4ISHL 1IQNL 4MMXB 2BQ7A 1IJQA 1WHFA 2Y7XB 1U8CB 1L5GB 2W2NE 1URKA 3DEMA 1EZQB 3KK6A 1O5DL 1FE2A 2W26B 1NFYB 3N8XA 4ZXYL 3ENSA 3RR3A 4JYVL 1W7XL 2WZPP 3N8YA 5K0HB 3KQDL 4Y76B 3TK5B 2Y5FL 4RUTA 1Z6EL 2BT7A 4X8VL 2Y7ZB 2XBYL 1IQFL 2Y5HL 2KNIA 5JVZA 1DX5I 1G1SA 1TOZA 3CS7L 5CKMA 1ZAQA 4D90A 1N1IA 3N8VA 3LTFB 4Z6AL 1IP0A 1MOXC 1CVUA 3ELAL 2Y38A 3N8YB 2K2TA 3R05A 3C9AC 1EPIA 2W2PE 3QCWA 1G2LB 3S6XA 1LK9A 2PHBB 1UZQA 3V65B 1IQGL 2Y5GL 1P9JA 3MQEA 2FLRL 1IQHL 2P3UA 1LMMA 1CCVA 1ADXA 2D1JB 4CSYA 1DQBA 4CUDA 4M11A 2BZ6L 3FFGL 2UWPB 5L2ZL 1IVOC 1X7AL 2FZZL 5L2YL 1EPJA 4GU4A 4YZUB 2RNLA 2W3IB 1HZ8A 2WPJE 2Y80B 3HS7A 4NA9L 1KLOA 5JVYA 2FLGA 3ZYJB 2GD4A 5E8DA 4D0EA 2BQWA 1F7EA 4A7IA 1L3YA 4BDXA 2Y81B 1XKAL 2VWOL 2J38B 2VWMK 2PR3B 2MGRA 1YGCL 1ATEA 3MDLA 4Z0LA 3KCGL 3HPTA 1LQDA 4NGAL 3LN0A 1NFWB 2EI6B 4CUFA 3BT2A 2BSFA 2KL7A 2RHPA 3HS5A 3FCSB 2WPHE 4TGFA 4XL1A 1FSBA 3TH3L 3GCXE 2H9EC 1F7MA 2YGPA 3TGFA 3KQBL 1PXXA 3FBYA 4A94C 1W8BL 5EGMB 1HT8A 2J95B 1Z6CA 3LTGD 2AYLA 5JB9E 2P16L 1CX2A 4D0FA 1NQLB 2EI7B 2I9AA 1Q4GA 5JBCE 1IGXA 2ADXA 1EQGA 1G2MB 2TGFA 2HOXA 1NZIA 3CFWA 2MHPA 3N8WA 1CCFA 1HRFA 1IQLL 2B7DL 2WG4B 3HS6A 1CVWL 3LC5B 3KRKA 2P3FN 4X8SL 1PFXL 3GISX 4MMZB 4ZAEB 2VWNL 2MGPA 1K37A 4M10A 3SW2A 1V1HA 3H5CB 2WFXB 3N8WB 2BO2A 1UZJA 3POYA 1KLJL 2HORA 1IOEL 2J2UB 3SOVA 3QH0A 5KIRA 4BTIA 3ZYIB 2VJ3A 2J34B 1HCGB 4BXSA 2BOXA
chains in the Genus database with same CATH topology
3KQCL 1OB1C 4Y79B 1YUKB 1FF7A 1TLEA 3NT1A 1PTHA 5I46L 2UWLB 2OYEP 1PRHA 1HAEA 1QFKL 2VH0B 3M36L 2WPME 2OYUP 1J9CL 5IKQA 1UZKA 1B9WA 1EMOA 1JL9A 5IKRA 3V64C 2J4IB 3P5BL 1PGEA 4RRWA 3HO5A 2KV4A 3U73A 5CISA 1IQKL 2JKHL 2P28B 3NTGA 5CKNA 4BDWA 4OTYA 4COXA 4Y6DB 5JBBE 4O1ZA 1SZBA 1M1XB 1FAXL 2BOKL 1KLIL 1NPEB 2XBWL 4JZFL 3OLTA 1NFUB 3EGFA 3NTBA 5KN5C 2P93L 1LPGA 3M37L 3LAQA 2K2SB 1APQA 1HX2A 3Q3KB 2Q1JB 4XLWA 1CEJA 1EAIC 2P95L 4NG9L 4C16A 2VWLL 2BOUA 3NJPC 1G1TA 2WYGB 1LPKA 5JBAE 2FLBL 4JYUL 1EPGA 4RS0A 4FM5A 2W2QE 4MMYB 1EBVA 1WU1B 2VVCK 4PH9A 4LORA 2YGOA 4BTTA 4RRYA 5IKVA 4LMFA 1FJSL 1DIYA 1TPGA 3IITB 1XFEA 3PGHA 4RRZA 1XDTR 1YUGA 4Y7AB 2XC5L 2CJIB 1G1RA 2RA0L 1ATAA 2P3TA 1MQ5L 2P3FL 1ATBA 1HT5A 3U7UG 3QMOA 2W86A 1NFXB 1IQML 2XBVL 3ASIA 4RRXA 2WPKE 4ISIL 2F9BL 2KB9A 1C5MF 1U67A 3BPSE 1JBUL 1A3PA 4YT7L 1LMJA 6COXA 2DDUA 3CENL 4BTUA 5COXA 1KSNB 2I9BA 4OTJA 4BXWA 3K9XA 4JZEL 1FFMA 3F1SB 1I0UA 3TZIA 3F6UL 1WHEA 1K36A 1DVAL 1G1QA 3OLUA 2WFTA 3GCWE 3SOBB 1P0SL 2W2OE 3TBDA 1YUFA 1MQ6L 5CKQA 4Y7BB 5JB8E 4G1MB 4X8UL 4ZHAB 3KQEL 1IQJL 2NPRA 1F0SB 2PUQL 2WYJB 1N7DA 1EMNA 1HJ7A 1V3XB 3CA7A 2WPLE 4AQTA 1JV2B 1LPZA 1UZPA 1KIGL 2BOHA 4YT6L 2YGQA 2BMGA 1BF9A 1IOXA 5FDQA 2VVVL 3SOQA 4XBMA 2BQ6A 1FAKL 1IGZA 1XKBA 4JZDL 1GK5A 2XC0L 3IJEB 3N8ZA 2WG3C 3Q7DA 2W2ME 4ZH8B 2P94L 5JW1A 5IKTA 4Y71B 2WPIE 1IQEL 2Y82B 1COUA 3LIWB 3HO4A 1RFNB 5F19A 2J94B 1APOA 4O02B 1IQIL 2XC4L 2XBXL 3LC3B 2M74A 2H9EL 1AUTL 1EGFA 1NT0A 2P26A 1HAFA 2W3KB 1HREA 3LN1A 3KL6B 1CQEA 4E1GA 3HO3A 3ZYGA 2EI8B 1DDXA 1ATDA 4CUEA 3BT1A 2UWOB 4ZXXL 1F0RB 2VH6B 2FD6A 2G00L 2VVUL 4X8TL 5L30L 5F1AA 1YO8A 4Z0KB 1EQHA 1EPHA 3TK6B 4ISHL 1IQNL 4MMXB 2BQ7A 1IJQA 1WHFA 2Y7XB 1U8CB 1L5GB 2W2NE 1URKA 3DEMA 1EZQB 3KK6A 1O5DL 1FE2A 2W26B 1NFYB 3N8XA 4ZXYL 3ENSA 3RR3A 4JYVL 1W7XL 2WZPP 3N8YA 5K0HB 3KQDL 4Y76B 3TK5B 2Y5FL 4RUTA 1Z6EL 4X8VL 2Y7ZB 2XBYL 1IQFL 2Y5HL 2KNIA 5JVZA 1DX5I 1G1SA 1TOZA 3CS7L 5CKMA 1ZAQA 4D90A 1N1IA 3N8VA 3LTFB 4Z6AL 1IP0A 1MOXC 1CVUA 3ELAL 2Y38A 3N8YB 2K2TA 3R05A 3C9AC 1EPIA 2W2PE 3QCWA 1G2LB 3S6XA 2PHBB 1UZQA 3V65B 1IQGL 2Y5GL 1P9JA 3MQEA 2FLRL 1IQHL 2P3UA 1LMMA 1CCVA 1ADXA 2D1JB 4CSYA 1DQBA 4CUDA 4M11A 2BZ6L 3FFGL 2UWPB 5L2ZL 1IVOC 1X7AL 2FZZL 5L2YL 1EPJA 4YZUB 2RNLA 2W3IB 1HZ8A 2WPJE 2Y80B 3HS7A 4NA9L 1KLOA 5JVYA 2FLGA 3ZYJB 2GD4A 5E8DA 4D0EA 2BQWA 1F7EA 4A7IA 1L3YA 4BDXA 2Y81B 1XKAL 2VWOL 2J38B 2VWMK 2PR3B 2MGRA 1YGCL 1ATEA 3MDLA 4Z0LA 3KCGL 3HPTA 1LQDA 4NGAL 3LN0A 1NFWB 2EI6B 4CUFA 3BT2A 2KL7A 2RHPA 3HS5A 3FCSB 2WPHE 4TGFA 4XL1A 1FSBA 3TH3L 3GCXE 2H9EC 1F7MA 2YGPA 3TGFA 3KQBL 1PXXA 3FBYA 4A94C 1W8BL 5EGMB 1HT8A 2J95B 1Z6CA 3LTGD 2AYLA 5JB9E 2P16L 1CX2A 4D0FA 1NQLB 2EI7B 2I9AA 1Q4GA 5JBCE 1IGXA 2ADXA 1EQGA 1G2MB 2TGFA 1NZIA 3CFWA 2MHPA 3N8WA 1CCFA 1HRFA 1IQLL 2B7DL 2WG4B 3HS6A 1CVWL 3LC5B 3KRKA 2P3FN 4X8SL 1PFXL 3GISX 4MMZB 4ZAEB 2VWNL 2MGPA 1K37A 4M10A 3SW2A 3H5CB 2WFXB 3N8WB 2BO2A 1UZJA 3POYA 1KLJL 1IOEL 2J2UB 3SOVA 3QH0A 5KIRA 4BTIA 3ZYIB 2VJ3A 2J34B 1HCGB 4BXSA 2BOXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KQC L;  1OB1 C;  4Y79 B;  1YUK B;  1FF7 A;  1TLE A;  3NT1 A;  1PTH A;  5I46 L;  2UWL B;  2OYE P;  1PRH A;  1HAE A;  1QFK L;  2VH0 B;  3M36 L;  2WPM E;  2OYU P;  1J9C L;  5IKQ A;  1UZK A;  1B9W A;  1EMO A;  1JL9 A;  5IKR A;  3V64 C;  2J4I B;  3P5B L;  1PGE A;  4RRW A;  3HO5 A;  2KV4 A;  3U73 A;  5CIS A;  1IQK L;  2JKH L;  2P28 B;  3NTG A;  5CKN A;  4BDW A;  4OTY A;  4COX A;  4Y6D B;  5JBB E;  4O1Z A;  1SZB A;  1M1X B;  1FAX L;  2BOK L;  1KLI L;  1NPE B;  2XBW L;  4JZF L;  3OLT A;  1NFU B;  3EGF A;  3NTB A;  5KN5 C;  2P93 L;  1LPG A;  3M37 L;  3LAQ A;  2K2S B;  1APQ A;  1HX2 A;  3Q3K B;  2Q1J B;  4XLW A;  1CEJ A;  1EAI C;  2P95 L;  4NG9 L;  4C16 A;  2VWL L;  2BOU A;  3NJP C;  1G1T A;  2WYG B;  1LPK A;  5JBA E;  2FLB L;  4JYU L;  1EPG A;  4RS0 A;  4FM5 A;  2W2Q E;  4MMY B;  1EBV A;  1WU1 B;  2VVC K;  4PH9 A;  4LOR A;  2YGO A;  4BTT A;  4RRY A;  5IKV A;  4LMF A;  1FJS L;  1DIY A;  1TPG A;  3IIT B;  1XFE A;  3PGH A;  4RRZ A;  1XDT R;  1YUG A;  4Y7A B;  2XC5 L;  2CJI B;  1G1R A;  2RA0 L;  1ATA A;  2P3T A;  1MQ5 L;  2P3F L;  1ATB A;  1HT5 A;  3U7U G;  3QMO A;  2W86 A;  1NFX B;  1IQM L;  2XBV L;  3ASI A;  4RRX A;  2WPK E;  4ISI L;  2F9B L;  2KB9 A;  1C5M F;  1U67 A;  3BPS E;  1JBU L;  1A3P A;  4YT7 L;  1LMJ A;  6COX A;  2DDU A;  3CEN L;  4BTU A;  5COX A;  1KSN B;  2I9B A;  4OTJ A;  4BXW A;  3K9X A;  4JZE L;  1FFM A;  3F1S B;  1I0U A;  3TZI A;  3F6U L;  1WHE A;  1K36 A;  1DVA L;  1G1Q A;  3OLU A;  2WFT A;  3GCW E;  3SOB B;  1P0S L;  2W2O E;  3TBD A;  1YUF A;  1MQ6 L;  5CKQ A;  4Y7B B;  5JB8 E;  4G1M B;  4X8U L;  4ZHA B;  3KQE L;  1IQJ L;  2NPR A;  1F0S B;  2PUQ L;  2WYJ B;  1N7D A;  1EMN A;  1HJ7 A;  1V3X B;  3CA7 A;  2WPL E;  4AQT A;  1JV2 B;  1LPZ A;  1UZP A;  1KIG L;  2BOH A;  4YT6 L;  2BMG A;  1BF9 A;  1IOX A;  5FDQ A;  2VVV L;  3SOQ A;  4XBM A;  2BQ6 A;  1FAK L;  1IGZ A;  1XKB A;  4JZD L;  1GK5 A;  2XC0 L;  3IJE B;  3N8Z A;  2WG3 C;  3Q7D A;  2W2M E;  4ZH8 B;  2P94 L;  5JW1 A;  5IKT A;  4Y71 B;  2WPI E;  1IQE L;  2Y82 B;  1COU A;  3LIW B;  3HO4 A;  1RFN B;  5F19 A;  2J94 B;  1APO A;  4O02 B;  1IQI L;  2XC4 L;  2XBX L;  3LC3 B;  2M74 A;  2H9E L;  1AUT L;  1EGF A;  1NT0 A;  2P26 A;  1HAF A;  2W3K B;  1HRE A;  3LN1 A;  3KL6 B;  1CQE A;  4E1G A;  3HO3 A;  3ZYG A;  2EI8 B;  1DDX A;  1ATD A;  4CUE A;  3BT1 A;  2UWO B;  4ZXX L;  1F0R B;  2VH6 B;  2FD6 A;  2G00 L;  2VVU L;  4X8T L;  5L30 L;  5F1A A;  1YO8 A;  4Z0K B;  1EQH A;  1EPH A;  3TK6 B;  4ISH L;  1IQN L;  4MMX B;  2BQ7 A;  1IJQ A;  1WHF A;  2Y7X B;  1U8C B;  1L5G B;  2W2N E;  1URK A;  3DEM A;  1EZQ B;  3KK6 A;  1O5D L;  1FE2 A;  2W26 B;  1NFY B;  3N8X A;  4ZXY L;  3ENS A;  3RR3 A;  4JYV L;  1W7X L;  3N8Y A;  5K0H B;  3KQD L;  4Y76 B;  3TK5 B;  2Y5F L;  4RUT A;  1Z6E L;  4X8V L;  2Y7Z B;  2XBY L;  1IQF L;  2Y5H L;  5JVZ A;  1DX5 I;  1G1S A;  1TOZ A;  3CS7 L;  5CKM A;  1ZAQ A;  4D90 A;  1N1I A;  3N8V A;  3LTF B;  4Z6A L;  1IP0 A;  1MOX C;  1CVU A;  3ELA L;  2Y38 A;  3N8Y B;  2K2T A;  3R05 A;  3C9A C;  1EPI A;  2W2P E;  3QCW A;  1G2L B;  2PHB B;  1UZQ A;  3V65 B;  1IQG L;  2Y5G L;  1P9J A;  3MQE A;  2FLR L;  1IQH L;  2P3U A;  1CCV A;  1ADX A;  2D1J B;  4CSY A;  1DQB A;  4CUD A;  4M11 A;  2BZ6 L;  3FFG L;  2UWP B;  5L2Z L;  1IVO C;  1X7A L;  2FZZ L;  5L2Y L;  1EPJ A;  4YZU B;  2RNL A;  2W3I B;  1HZ8 A;  2WPJ E;  2Y80 B;  3HS7 A;  4NA9 L;  1KLO A;  5JVY A;  2FLG A;  3ZYJ B;  2GD4 A;  5E8D A;  4D0E A;  2BQW A;  1F7E A;  4A7I A;  1L3Y A;  4BDX A;  2Y81 B;  1XKA L;  2VWO L;  2J38 B;  2VWM K;  2PR3 B;  2MGR A;  1YGC L;  1ATE A;  3MDL A;  4Z0L A;  3KCG L;  3HPT A;  1LQD A;  4NGA L;  3LN0 A;  1NFW B;  2EI6 B;  4CUF A;  3BT2 A;  2KL7 A;  2RHP A;  3HS5 A;  3FCS B;  2WPH E;  4TGF A;  4XL1 A;  1FSB A;  3TH3 L;  3GCX E;  1F7M A;  2YGP A;  3TGF A;  3KQB L;  1PXX A;  3FBY A;  1W8B L;  5EGM B;  1HT8 A;  2J95 B;  1Z6C A;  3LTG D;  2AYL A;  5JB9 E;  2P16 L;  1CX2 A;  4D0F A;  1NQL B;  2EI7 B;  2I9A A;  1Q4G A;  5JBC E;  1IGX A;  2ADX A;  1EQG A;  1G2M B;  2TGF A;  1NZI A;  3CFW A;  2MHP A;  3N8W A;  1CCF A;  1HRF A;  1IQL L;  2B7D L;  2WG4 B;  3HS6 A;  1CVW L;  3LC5 B;  3KRK A;  2P3F N;  4X8S L;  1PFX L;  3GIS X;  4MMZ B;  4ZAE B;  2VWN L;  2MGP A;  1K37 A;  4M10 A;  3SW2 A;  3H5C B;  2WFX B;  3N8W B;  2BO2 A;  1UZJ A;  3POY A;  1KLJ L;  1IOE L;  2J2U B;  3SOV A;  3QH0 A;  5KIR A;  4BTI A;  3ZYI B;  2VJ3 A;  2J34 B;  1HCG B;  4BXS A;  2BOX A; 
#chains in the Genus database with same CATH topology
 3KQC L;  1OB1 C;  4Y79 B;  1YUK B;  1FF7 A;  1TLE A;  3NT1 A;  1PTH A;  5I46 L;  2UWL B;  2OYE P;  1PRH A;  1HAE A;  1QFK L;  2VH0 B;  3M36 L;  2WPM E;  2OYU P;  1J9C L;  5IKQ A;  1UZK A;  1B9W A;  1EMO A;  1JL9 A;  5IKR A;  3V64 C;  2J4I B;  3P5B L;  1PGE A;  4RRW A;  3HO5 A;  2KV4 A;  3U73 A;  5CIS A;  1IQK L;  2JKH L;  2P28 B;  3NTG A;  5CKN A;  4BDW A;  4OTY A;  4COX A;  4Y6D B;  5JBB E;  4O1Z A;  1SZB A;  1M1X B;  1FAX L;  2BOK L;  1KLI L;  1NPE B;  2XBW L;  4JZF L;  3OLT A;  1NFU B;  3EGF A;  3NTB A;  5KN5 C;  2P93 L;  1LPG A;  3M37 L;  3LAQ A;  4GU3 A;  2K2S B;  1APQ A;  1HX2 A;  3Q3K B;  2Q1J B;  4XLW A;  1CEJ A;  1EAI C;  2P95 L;  1V1I A;  4NG9 L;  4C16 A;  2VWL L;  2BOU A;  3NJP C;  1G1T A;  2WYG B;  1LPK A;  5JBA E;  2FLB L;  4JYU L;  1EPG A;  4RS0 A;  4FM5 A;  2W2Q E;  4MMY B;  1EBV A;  1WU1 B;  2VVC K;  4PH9 A;  4LOR A;  2YGO A;  4BTT A;  4RRY A;  5IKV A;  4LMF A;  1FJS L;  1DIY A;  1TPG A;  3IIT B;  1XFE A;  3PGH A;  4RRZ A;  1XDT R;  1YUG A;  1QIU A;  4Y7A B;  2XC5 L;  2CJI B;  2JJL A;  1G1R A;  2RA0 L;  1ATA A;  2P3T A;  1MQ5 L;  2P3F L;  1ATB A;  1HT5 A;  3U7U G;  3QMO A;  2W86 A;  1NFX B;  1IQM L;  2XBV L;  3ASI A;  4RRX A;  2WPK E;  4ISI L;  2F9B L;  2KB9 A;  1C5M F;  1U67 A;  3BPS E;  1JBU L;  1A3P A;  4YT7 L;  1LMJ A;  6COX A;  2DDU A;  3CEN L;  4BTU A;  5COX A;  1KSN B;  2I9B A;  4OTJ A;  4BXW A;  3K9X A;  4JZE L;  1FFM A;  3F1S B;  1I0U A;  3TZI A;  2BT8 A;  3F6U L;  1WHE A;  1K36 A;  1DVA L;  1G1Q A;  3OLU A;  2WFT A;  3GCW E;  3SOB B;  1P0S L;  2W2O E;  3TBD A;  1YUF A;  1MQ6 L;  5CKQ A;  4Y7B B;  5JB8 E;  4G1M B;  4X8U L;  4ZHA B;  3KQE L;  1IQJ L;  2NPR A;  1F0S B;  2PUQ L;  2WYJ B;  1N7D A;  1EMN A;  1HJ7 A;  1V3X B;  3CA7 A;  2WPL E;  4AQT A;  1JV2 B;  1LPZ A;  1UZP A;  1KIG L;  2BOH A;  4YT6 L;  2YGQ A;  2BMG A;  1BF9 A;  1IOX A;  5FDQ A;  2VVV L;  3SOQ A;  4XBM A;  2BQ6 A;  1FAK L;  1IGZ A;  1XKB A;  4JZD L;  1GK5 A;  2XC0 L;  3IJE B;  3N8Z A;  2WG3 C;  3Q7D A;  2W2M E;  4ZH8 B;  2P94 L;  5JW1 A;  5IKT A;  1KKE A;  4Y71 B;  2WPI E;  1IQE L;  2Y82 B;  1COU A;  3LIW B;  3HO4 A;  1RFN B;  5F19 A;  2J94 B;  1APO A;  4O02 B;  1IQI L;  2XC4 L;  2XBX L;  3LC3 B;  2M74 A;  2H9E L;  1AUT L;  1EGF A;  1NT0 A;  2P26 A;  1HAF A;  2W3K B;  1HRE A;  3LN1 A;  3KL6 B;  1CQE A;  4E1G A;  3HO3 A;  3ZYG A;  2EI8 B;  1DDX A;  1ATD A;  4CUE A;  3BT1 A;  2UWO B;  4ZXX L;  1F0R B;  2VH6 B;  2FD6 A;  2G00 L;  2VVU L;  4X8T L;  5L30 L;  5F1A A;  1YO8 A;  2VRS A;  4Z0K B;  1EQH A;  1EPH A;  3TK6 B;  4ISH L;  1IQN L;  4MMX B;  2BQ7 A;  1IJQ A;  1WHF A;  2Y7X B;  1U8C B;  1L5G B;  2W2N E;  1URK A;  3DEM A;  1EZQ B;  3KK6 A;  1O5D L;  1FE2 A;  2W26 B;  1NFY B;  3N8X A;  4ZXY L;  3ENS A;  3RR3 A;  4JYV L;  1W7X L;  2WZP P;  3N8Y A;  5K0H B;  3KQD L;  4Y76 B;  3TK5 B;  2Y5F L;  4RUT A;  1Z6E L;  2BT7 A;  4X8V L;  2Y7Z B;  2XBY L;  1IQF L;  2Y5H L;  2KNI A;  5JVZ A;  1DX5 I;  1G1S A;  1TOZ A;  3CS7 L;  5CKM A;  1ZAQ A;  4D90 A;  1N1I A;  3N8V A;  3LTF B;  4Z6A L;  1IP0 A;  1MOX C;  1CVU A;  3ELA L;  2Y38 A;  3N8Y B;  2K2T A;  3R05 A;  3C9A C;  1EPI A;  2W2P E;  3QCW A;  1G2L B;  3S6X A;  1LK9 A;  2PHB B;  1UZQ A;  3V65 B;  1IQG L;  2Y5G L;  1P9J A;  3MQE A;  2FLR L;  1IQH L;  2P3U A;  1LMM A;  1CCV A;  1ADX A;  2D1J B;  4CSY A;  1DQB A;  4CUD A;  4M11 A;  2BZ6 L;  3FFG L;  2UWP B;  5L2Z L;  1IVO C;  1X7A L;  2FZZ L;  5L2Y L;  1EPJ A;  4GU4 A;  4YZU B;  2RNL A;  2W3I B;  1HZ8 A;  2WPJ E;  2Y80 B;  3HS7 A;  4NA9 L;  1KLO A;  5JVY A;  2FLG A;  3ZYJ B;  2GD4 A;  5E8D A;  4D0E A;  2BQW A;  1F7E A;  4A7I A;  1L3Y A;  4BDX A;  2Y81 B;  1XKA L;  2VWO L;  2J38 B;  2VWM K;  2PR3 B;  2MGR A;  1YGC L;  1ATE A;  3MDL A;  4Z0L A;  3KCG L;  3HPT A;  1LQD A;  4NGA L;  3LN0 A;  1NFW B;  2EI6 B;  4CUF A;  3BT2 A;  2BSF A;  2KL7 A;  2RHP A;  3HS5 A;  3FCS B;  2WPH E;  4TGF A;  4XL1 A;  1FSB A;  3TH3 L;  3GCX E;  2H9E C;  1F7M A;  2YGP A;  3TGF A;  3KQB L;  1PXX A;  3FBY A;  4A94 C;  1W8B L;  5EGM B;  1HT8 A;  2J95 B;  1Z6C A;  3LTG D;  2AYL A;  5JB9 E;  2P16 L;  1CX2 A;  4D0F A;  1NQL B;  2EI7 B;  2I9A A;  1Q4G A;  5JBC E;  1IGX A;  2ADX A;  1EQG A;  1G2M B;  2TGF A;  2HOX A;  1NZI A;  3CFW A;  2MHP A;  3N8W A;  1CCF A;  1HRF A;  1IQL L;  2B7D L;  2WG4 B;  3HS6 A;  1CVW L;  3LC5 B;  3KRK A;  2P3F N;  4X8S L;  1PFX L;  3GIS X;  4MMZ B;  4ZAE B;  2VWN L;  2MGP A;  1K37 A;  4M10 A;  3SW2 A;  1V1H A;  3H5C B;  2WFX B;  3N8W B;  2BO2 A;  1UZJ A;  3POY A;  1KLJ L;  2HOR A;  1IOE L;  2J2U B;  3SOV A;  3QH0 A;  5KIR A;  4BTI A;  3ZYI B;  2VJ3 A;  2J34 B;  1HCG B;  4BXS A;  2BOX A; 
#chains in the Genus database with same CATH homology
 3KQC L;  1OB1 C;  4Y79 B;  1YUK B;  1FF7 A;  1TLE A;  3NT1 A;  1PTH A;  5I46 L;  2UWL B;  2OYE P;  1PRH A;  1HAE A;  1QFK L;  2VH0 B;  3M36 L;  2WPM E;  2OYU P;  1J9C L;  5IKQ A;  1UZK A;  1B9W A;  1EMO A;  1JL9 A;  5IKR A;  3V64 C;  2J4I B;  3P5B L;  1PGE A;  4RRW A;  3HO5 A;  2KV4 A;  3U73 A;  5CIS A;  1IQK L;  2JKH L;  2P28 B;  3NTG A;  5CKN A;  4BDW A;  4OTY A;  4COX A;  4Y6D B;  5JBB E;  4O1Z A;  1SZB A;  1M1X B;  1FAX L;  2BOK L;  1KLI L;  1NPE B;  2XBW L;  4JZF L;  3OLT A;  1NFU B;  3EGF A;  3NTB A;  5KN5 C;  2P93 L;  1LPG A;  3M37 L;  3LAQ A;  2K2S B;  1APQ A;  1HX2 A;  3Q3K B;  2Q1J B;  4XLW A;  1CEJ A;  1EAI C;  2P95 L;  4NG9 L;  4C16 A;  2VWL L;  2BOU A;  3NJP C;  1G1T A;  2WYG B;  1LPK A;  5JBA E;  2FLB L;  4JYU L;  1EPG A;  4RS0 A;  4FM5 A;  2W2Q E;  4MMY B;  1EBV A;  1WU1 B;  2VVC K;  4PH9 A;  4LOR A;  2YGO A;  4BTT A;  4RRY A;  5IKV A;  4LMF A;  1FJS L;  1DIY A;  1TPG A;  3IIT B;  1XFE A;  3PGH A;  4RRZ A;  1XDT R;  1YUG A;  4Y7A B;  2XC5 L;  2CJI B;  1G1R A;  2RA0 L;  1ATA A;  2P3T A;  1MQ5 L;  2P3F L;  1ATB A;  1HT5 A;  3U7U G;  3QMO A;  2W86 A;  1NFX B;  1IQM L;  2XBV L;  3ASI A;  4RRX A;  2WPK E;  4ISI L;  2F9B L;  2KB9 A;  1C5M F;  1U67 A;  3BPS E;  1JBU L;  1A3P A;  4YT7 L;  1LMJ A;  6COX A;  2DDU A;  3CEN L;  4BTU A;  5COX A;  1KSN B;  2I9B A;  4OTJ A;  4BXW A;  3K9X A;  4JZE L;  1FFM A;  3F1S B;  1I0U A;  3TZI A;  3F6U L;  1WHE A;  1K36 A;  1DVA L;  1G1Q A;  3OLU A;  2WFT A;  3GCW E;  3SOB B;  1P0S L;  2W2O E;  3TBD A;  1YUF A;  1MQ6 L;  5CKQ A;  4Y7B B;  5JB8 E;  4G1M B;  4X8U L;  4ZHA B;  3KQE L;  1IQJ L;  2NPR A;  1F0S B;  2PUQ L;  2WYJ B;  1N7D A;  1EMN A;  1HJ7 A;  1V3X B;  3CA7 A;  2WPL E;  4AQT A;  1JV2 B;  1LPZ A;  1UZP A;  1KIG L;  2BOH A;  4YT6 L;  2YGQ A;  2BMG A;  1BF9 A;  1IOX A;  5FDQ A;  2VVV L;  3SOQ A;  4XBM A;  2BQ6 A;  1FAK L;  1IGZ A;  1XKB A;  4JZD L;  1GK5 A;  2XC0 L;  3IJE B;  3N8Z A;  2WG3 C;  3Q7D A;  2W2M E;  4ZH8 B;  2P94 L;  5JW1 A;  5IKT A;  4Y71 B;  2WPI E;  1IQE L;  2Y82 B;  1COU A;  3LIW B;  3HO4 A;  1RFN B;  5F19 A;  2J94 B;  1APO A;  4O02 B;  1IQI L;  2XC4 L;  2XBX L;  3LC3 B;  2M74 A;  2H9E L;  1AUT L;  1EGF A;  1NT0 A;  2P26 A;  1HAF A;  2W3K B;  1HRE A;  3LN1 A;  3KL6 B;  1CQE A;  4E1G A;  3HO3 A;  3ZYG A;  2EI8 B;  1DDX A;  1ATD A;  4CUE A;  3BT1 A;  2UWO B;  4ZXX L;  1F0R B;  2VH6 B;  2FD6 A;  2G00 L;  2VVU L;  4X8T L;  5L30 L;  5F1A A;  1YO8 A;  4Z0K B;  1EQH A;  1EPH A;  3TK6 B;  4ISH L;  1IQN L;  4MMX B;  2BQ7 A;  1IJQ A;  1WHF A;  2Y7X B;  1U8C B;  1L5G B;  2W2N E;  1URK A;  3DEM A;  1EZQ B;  3KK6 A;  1O5D L;  1FE2 A;  2W26 B;  1NFY B;  3N8X A;  4ZXY L;  3ENS A;  3RR3 A;  4JYV L;  1W7X L;  2WZP P;  3N8Y A;  5K0H B;  3KQD L;  4Y76 B;  3TK5 B;  2Y5F L;  4RUT A;  1Z6E L;  4X8V L;  2Y7Z B;  2XBY L;  1IQF L;  2Y5H L;  2KNI A;  5JVZ A;  1DX5 I;  1G1S A;  1TOZ A;  3CS7 L;  5CKM A;  1ZAQ A;  4D90 A;  1N1I A;  3N8V A;  3LTF B;  4Z6A L;  1IP0 A;  1MOX C;  1CVU A;  3ELA L;  2Y38 A;  3N8Y B;  2K2T A;  3R05 A;  3C9A C;  1EPI A;  2W2P E;  3QCW A;  1G2L B;  3S6X A;  2PHB B;  1UZQ A;  3V65 B;  1IQG L;  2Y5G L;  1P9J A;  3MQE A;  2FLR L;  1IQH L;  2P3U A;  1LMM A;  1CCV A;  1ADX A;  2D1J B;  4CSY A;  1DQB A;  4CUD A;  4M11 A;  2BZ6 L;  3FFG L;  2UWP B;  5L2Z L;  1IVO C;  1X7A L;  2FZZ L;  5L2Y L;  1EPJ A;  4YZU B;  2RNL A;  2W3I B;  1HZ8 A;  2WPJ E;  2Y80 B;  3HS7 A;  4NA9 L;  1KLO A;  5JVY A;  2FLG A;  3ZYJ B;  2GD4 A;  5E8D A;  4D0E A;  2BQW A;  1F7E A;  4A7I A;  1L3Y A;  4BDX A;  2Y81 B;  1XKA L;  2VWO L;  2J38 B;  2VWM K;  2PR3 B;  2MGR A;  1YGC L;  1ATE A;  3MDL A;  4Z0L A;  3KCG L;  3HPT A;  1LQD A;  4NGA L;  3LN0 A;  1NFW B;  2EI6 B;  4CUF A;  3BT2 A;  2KL7 A;  2RHP A;  3HS5 A;  3FCS B;  2WPH E;  4TGF A;  4XL1 A;  1FSB A;  3TH3 L;  3GCX E;  2H9E C;  1F7M A;  2YGP A;  3TGF A;  3KQB L;  1PXX A;  3FBY A;  4A94 C;  1W8B L;  5EGM B;  1HT8 A;  2J95 B;  1Z6C A;  3LTG D;  2AYL A;  5JB9 E;  2P16 L;  1CX2 A;  4D0F A;  1NQL B;  2EI7 B;  2I9A A;  1Q4G A;  5JBC E;  1IGX A;  2ADX A;  1EQG A;  1G2M B;  2TGF A;  1NZI A;  3CFW A;  2MHP A;  3N8W A;  1CCF A;  1HRF A;  1IQL L;  2B7D L;  2WG4 B;  3HS6 A;  1CVW L;  3LC5 B;  3KRK A;  2P3F N;  4X8S L;  1PFX L;  3GIS X;  4MMZ B;  4ZAE B;  2VWN L;  2MGP A;  1K37 A;  4M10 A;  3SW2 A;  3H5C B;  2WFX B;  3N8W B;  2BO2 A;  1UZJ A;  3POY A;  1KLJ L;  1IOE L;  2J2U B;  3SOV A;  3QH0 A;  5KIR A;  4BTI A;  3ZYI B;  2VJ3 A;  2J34 B;  1HCG B;  4BXS A;  2BOX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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