4ZXXL

Factor viia in complex with the inhibitor n-{3-[(2r)-1-{(2r)-2-[(1-aminoisoquinolin-6-yl)amino]-2-phenylacetyl}pyrrolidin-2-yl]-4-(propan-2-ylsulfonyl)phenyl}acetamide
Total Genus 11
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
55
structure length
55
Chain Sequence
ICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Design of Macrocyclic Coagulation Factor VIIa Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Coagulation factor VIIa heavy chain
total genus 11
structure length 55
sequence length 55
ec nomenclature ec 3.4.21.21: Coagulation factor VIIa.
pdb deposition date 2015-05-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 4zxxL00
4RRXA 3BT1A 1EBVA 1PGEA 2K2SB 2FLGA 3LN0A 2Y82B 1ATDA 1XKBA 1ATAA 3ASIA 1SZBA 4ZAEB 3QH0A 5CKMA 3KQEL 1KIGL 3R05A 1KLJL 2VJ3A 3MDLA 1Z6CA 1ADXA 4LMFA 3HS6A 2Y80B 2XBYL 2W2QE 4BDWA 5JB9E 3KK6A 1IGXA 2J94B 2P28B 2YGPA 1F0SB 1G1TA 1AUTL 3TBDA 4ZHAB 4Y76B 1CVUA 1NFYB 3LC5B 4XBMA 2VWNL 2WPJE 1PTHA 1M1XB 2XBXL 4RRZA 1COUA 1IQHL 1G1RA 1HREA 1UZJA 3QCWA 1PXXA 4OTJA 2XC4L 1C5MF 2Y7ZB 3BT2A 1FAKL 1F7MA 3ZYJB 1TOZA 2OYEP 2FLBL 3TK5B 4BTUA 1K37A 2WYJB 2EI6B 5I46L 2W2NE 3IJEB 4ISIL 4G1MB 4Y7BB 1G2MB 5JBAE 3U73A 5FDQA 3N8VA 2F9BL 2M74A 1HJ7A 2J34B 1G1SA 1CQEA 4NGAL 2VVCK 1IVOC 2Y38A 2TGFA 1ZAQA 1WHFA 1IOXA 1WU1B 1XKAL 5L30L 5CISA 2WPIE 2RHPA 5IKVA 1IQIL 2MGRA 4TGFA 2KV4A 2JKHL 1NPEB 4ISHL 2UWLB 1FFMA 2WPHE 5E8DA 4CUDA 4Y6DB 3HS5A 1DIYA 2XBWL 2P16L 2Y81B 4XL1A 4O1ZA 1EMNA 4AQTA 1K36A 1EMOA 1HAFA 2W2ME 1IQNL 4MMXB 2J2UB 5IKRA 3F1SB 1HT5A 3KRKA 3KCGL 1YUKB 1HRFA 1DVAL 4JYUL 2Y7XB 5JB8E 5KN5C 4Y71B 2W2PE 1FE2A 1UZPA 2FD6A 2MGPA 3FBYA 5K0HB 1IGZA 1CVWL 2UWOB 1DDXA 3Q7DA 2Y5GL 5CKNA 5L2ZL 1NFWB 1YUGA 2VWLL 4Y79B 3N8XA 1ATBA 3TH3L 1Q4GA 1NFUB 1L5GB 2RNLA 4C16A 3SOVA 3TZIA 2WG3C 3GCWE 2I9BA 2W3IB 2H9EL 1EPJA 4JZDL 3U7UG 1KSNB 1LQDA 1CCFA 3HO3A 2W3KB 2EI8B 4D0FA 4D0EA 1IJQA 4Y7AB 1IOEL 1WHEA 1JL9A 1XDTR 1G2LB 3SOBB 4YT7L 1URKA 1CEJA 4FM5A 2WFXB 2WFTA 4NA9L 3NT1A 4CSYA 3N8YA 1IQGL 4YT6L 1LPGA 1YGCL 1HAEA 3HS7A 1LPKA 5KIRA 4X8TL 3LN1A 2AYLA 1FSBA 1YO8A 3LIWB 4BTIA 1BF9A 1IQJL 3LC3B 3HO4A 1OB1C 3KQCL 1G1QA 1J9CL 1JBUL 1EZQB 4MMZB 2XC0L 1B9WA 2WG4B 3NTBA 5JVYA 2EI7B 2WPKE 2YGOA 3CFWA 3BPSE 5JBCE 3OLTA 4E1GA 4JZFL 2PHBB 1I0UA 2MHPA 1LMJA 3SW2A 5IKTA 1IQML 4A7IA 2BQ6A 2Y5HL 2BOUA 4Z0KB 1TPGA 3H5CB 2J95B 3P5BL 4YZUB 4M10A 4CUEA 5JW1A 1N1IA 2BZ6L 4ZH8B 2P95L 2P3FL 2PUQL 2W2OE 1EAIC 1CX2A 3ZYIB 1RFNB 2BO2A 2W86A 1EPIA 3GCXE 1ATEA 4LORA 2J38B 4ZXYL 2B7DL 5CKQA 2GD4A 2OYUP 3N8ZA 3Q3KB 4Z0LA 2KL7A 4COXA 5JBBE 3RR3A 1HCGB 4CUFA 2P3FN 1EGFA 3LTGD 1N7DA 1U8CB 4BXSA 4RUTA 4RRYA 5F1AA 1IQKL 1NQLB 4BXWA 2Q1JB 1EQHA 1W8BL 3ENSA 1JV2B 2XC5L 3V65B 1IQLL 2D1JB 2P3TA 3KL6B 3CENL 4D90A 2P94L 3M36L 3M37L 2XBVL 3TGFA 1V3XB 1LPZA 3HO5A 1P0SL 4MMYB 1UZKA 2DDUA 3HPTA 1GK5A 3POYA 1A3PA 5EGMB 2BOHA 1MQ6L 1DX5I 4JZEL 1L3YA 1XFEA 1HX2A 1IQEL 1O5DL 1FJSL 3KQBL 1DQBA 3CS7L 2WYGB 2Y5FL 1CCVA 3N8YB 3IITB 1EPHA 6COXA 1NZIA 1X7AL 2WPME 1FF7A 2VVVL 3GISX 1F0RB 3V64C 3F6UL 2FZZL 2CJIB 3LTFB 2UWPB 3NTGA 1NT0A 1YUFA 2PR3B 3DEMA 5L2YL 4RS0A 1U67A 4X8VL 1HZ8A 3MQEA 2VH6B 4BTTA 2NPRA 4PH9A 2W26B 1UZQA 2VWMK 3N8WA 1PRHA 1QFKL 3LAQA 2BQ7A 2VWOL 2G00L 2BOXA 5COXA 3FFGL 3N8WB 5JVZA 1MOXC 4O02B 4Z6AL 3ZYGA 3FCSB 1F7EA 2I9AA 1P9JA 2WPLE 2RA0L 4RRWA 4BDXA 2VVUL 5F19A 3K9XA 3C9AC 1EQGA 4NG9L 3NJPC 1KLIL 4XLWA 1EPGA 3TK6B 2BQWA 4ZXXL 5IKQA 2BOKL 1TLEA 1HT8A 4X8SL 2J4IB 3SOQA 2P26A 2FLRL 2P93L 1W7XL 2P3UA 4M11A 3ELAL 1APOA 1KLOA 3OLUA 1IQFL 2ADXA 1MQ5L 3QMOA 3EGFA 3KQDL 2K2TA 3PGHA 4OTYA 2VH0B 2BMGA 4JYVL 1IP0A 1PFXL 1NFXB 3CA7A 1APQA 1Z6EL 4X8UL 1FAXL 2KB9A
chains in the Genus database with same CATH superfamily
4RRXA 3BT1A 1EBVA 1PGEA 2K2SB 2FLGA 3LN0A 2Y82B 1ATDA 1XKBA 1ATAA 3ASIA 1SZBA 4ZAEB 3QH0A 5CKMA 3KQEL 1KIGL 3R05A 4GU3A 1KLJL 2BSFA 2VJ3A 3MDLA 1Z6CA 1ADXA 4LMFA 3HS6A 2Y80B 2XBYL 2W2QE 4BDWA 5JB9E 1V1IA 3KK6A 1IGXA 2J94B 2P28B 2YGPA 1F0SB 1G1TA 1AUTL 3TBDA 4ZHAB 1V1HA 4Y76B 1CVUA 1NFYB 3LC5B 4XBMA 2VWNL 2WPJE 1PTHA 1M1XB 2XBXL 4RRZA 1COUA 1IQHL 1G1RA 1HREA 1UZJA 3QCWA 1PXXA 4OTJA 2XC4L 1C5MF 2Y7ZB 3BT2A 1FAKL 1F7MA 3ZYJB 1TOZA 2OYEP 2FLBL 3TK5B 4BTUA 1K37A 2WYJB 2EI6B 5I46L 2W2NE 3IJEB 4ISIL 4G1MB 4Y7BB 1G2MB 5JBAE 3U73A 5FDQA 3N8VA 2F9BL 2M74A 1HJ7A 2J34B 1G1SA 1CQEA 4NGAL 2VVCK 1IVOC 2Y38A 2TGFA 1ZAQA 1WHFA 1IOXA 1WU1B 1XKAL 5L30L 5CISA 2WPIE 2RHPA 5IKVA 1IQIL 2MGRA 4TGFA 2KV4A 2JKHL 1NPEB 4ISHL 2UWLB 1FFMA 2WPHE 5E8DA 4CUDA 4Y6DB 3HS5A 1DIYA 2XBWL 2VRSA 2P16L 2Y81B 4XL1A 4O1ZA 1EMNA 4AQTA 1K36A 1EMOA 1HAFA 2W2ME 1IQNL 4MMXB 2J2UB 5IKRA 3F1SB 1HT5A 3KRKA 3KCGL 1YUKB 1HRFA 1DVAL 4JYUL 3S6XA 2Y7XB 5JB8E 5KN5C 4Y71B 2W2PE 1FE2A 1UZPA 2FD6A 2MGPA 3FBYA 5K0HB 1IGZA 1CVWL 2UWOB 1DDXA 1KKEA 3Q7DA 2Y5GL 5CKNA 5L2ZL 1NFWB 1YUGA 2VWLL 4Y79B 3N8XA 1ATBA 3TH3L 1Q4GA 1NFUB 1L5GB 2BT8A 2RNLA 4C16A 3SOVA 3TZIA 2WG3C 3GCWE 2I9BA 2W3IB 2H9EL 1EPJA 4JZDL 3U7UG 1KSNB 1LQDA 1CCFA 3HO3A 2W3KB 4GU4A 2EI8B 2WZPP 4D0FA 4D0EA 1IJQA 4Y7AB 1IOEL 1WHEA 1JL9A 1XDTR 1G2LB 3SOBB 4YT7L 1URKA 1CEJA 4FM5A 2WFXB 2WFTA 4NA9L 3NT1A 4CSYA 3N8YA 1IQGL 4YT6L 1LPGA 1YGCL 2HORA 1HAEA 3HS7A 1LPKA 5KIRA 4X8TL 3LN1A 2AYLA 1FSBA 1YO8A 3LIWB 4BTIA 1BF9A 1IQJL 3LC3B 3HO4A 1OB1C 3KQCL 1LK9A 1G1QA 2HOXA 1J9CL 1JBUL 1EZQB 4MMZB 2XC0L 1B9WA 2WG4B 3NTBA 5JVYA 2EI7B 2WPKE 2YGOA 3CFWA 3BPSE 5JBCE 3OLTA 4E1GA 4JZFL 2PHBB 1I0UA 2MHPA 1LMJA 3SW2A 5IKTA 1IQML 4A7IA 2BQ6A 2Y5HL 2BOUA 4Z0KB 1TPGA 3H5CB 2J95B 3P5BL 4YZUB 4M10A 4CUEA 5JW1A 1N1IA 2BZ6L 4ZH8B 1QIUA 2P95L 2P3FL 2PUQL 2W2OE 1EAIC 1CX2A 3ZYIB 1RFNB 2BO2A 2W86A 1EPIA 3GCXE 1ATEA 4LORA 2J38B 4ZXYL 2B7DL 5CKQA 2GD4A 2OYUP 3N8ZA 3Q3KB 4Z0LA 2KL7A 4COXA 5JBBE 3RR3A 1HCGB 4CUFA 2P3FN 1EGFA 3LTGD 1N7DA 1U8CB 4BXSA 4RUTA 4RRYA 5F1AA 1IQKL 1NQLB 4BXWA 2Q1JB 1EQHA 1W8BL 3ENSA 4A94C 1JV2B 2XC5L 3V65B 1IQLL 2D1JB 2P3TA 3KL6B 3CENL 2KNIA 4D90A 2P94L 3M36L 3M37L 2XBVL 3TGFA 1V3XB 1LPZA 3HO5A 1P0SL 4MMYB 1UZKA 2DDUA 3HPTA 1GK5A 3POYA 1A3PA 5EGMB 2JJLA 2BOHA 1MQ6L 1DX5I 4JZEL 1L3YA 1XFEA 1HX2A 1IQEL 1O5DL 1FJSL 3KQBL 1DQBA 3CS7L 2WYGB 2Y5FL 1CCVA 3N8YB 3IITB 1EPHA 6COXA 1NZIA 1X7AL 2WPME 1FF7A 2VVVL 3GISX 1F0RB 3V64C 3F6UL 2FZZL 2CJIB 3LTFB 2UWPB 3NTGA 1NT0A 1YUFA 2PR3B 3DEMA 5L2YL 4RS0A 1U67A 4X8VL 1HZ8A 3MQEA 2VH6B 4BTTA 2NPRA 4PH9A 2W26B 1UZQA 2VWMK 3N8WA 1PRHA 1QFKL 3LAQA 2BQ7A 2VWOL 2G00L 2BOXA 5COXA 3FFGL 3N8WB 5JVZA 1MOXC 4O02B 4Z6AL 2YGQA 3ZYGA 3FCSB 1F7EA 2I9AA 1P9JA 2WPLE 2RA0L 4RRWA 4BDXA 2VVUL 5F19A 3K9XA 2H9EC 3C9AC 1EQGA 4NG9L 1LMMA 3NJPC 1KLIL 4XLWA 1EPGA 3TK6B 2BQWA 4ZXXL 5IKQA 2BOKL 1TLEA 1HT8A 4X8SL 2J4IB 3SOQA 2P26A 2FLRL 2P93L 1W7XL 2P3UA 4M11A 3ELAL 1APOA 1KLOA 3OLUA 1IQFL 2ADXA 1MQ5L 3QMOA 3EGFA 3KQDL 2K2TA 3PGHA 4OTYA 2VH0B 2BMGA 4JYVL 1IP0A 1PFXL 2BT7A 1NFXB 3CA7A 1APQA 1Z6EL 4X8UL 1FAXL 2KB9A
chains in the Genus database with same CATH topology
4RRXA 3BT1A 1EBVA 1PGEA 2K2SB 2FLGA 3LN0A 2Y82B 1ATDA 1XKBA 1ATAA 3ASIA 1SZBA 4ZAEB 3QH0A 5CKMA 3KQEL 1KIGL 3R05A 1KLJL 2VJ3A 3MDLA 1Z6CA 1ADXA 4LMFA 3HS6A 2Y80B 2XBYL 2W2QE 4BDWA 5JB9E 3KK6A 1IGXA 2J94B 2P28B 2YGPA 1F0SB 1G1TA 1AUTL 3TBDA 4ZHAB 4Y76B 1CVUA 1NFYB 3LC5B 4XBMA 2VWNL 2WPJE 1PTHA 1M1XB 2XBXL 4RRZA 1COUA 1IQHL 1G1RA 1HREA 1UZJA 3QCWA 1PXXA 4OTJA 2XC4L 1C5MF 2Y7ZB 3BT2A 1FAKL 1F7MA 3ZYJB 1TOZA 2OYEP 2FLBL 3TK5B 4BTUA 1K37A 2WYJB 2EI6B 5I46L 2W2NE 3IJEB 4ISIL 4G1MB 4Y7BB 1G2MB 5JBAE 3U73A 5FDQA 3N8VA 2F9BL 2M74A 1HJ7A 2J34B 1G1SA 1CQEA 4NGAL 2VVCK 1IVOC 2Y38A 2TGFA 1ZAQA 1WHFA 1IOXA 1WU1B 1XKAL 5L30L 5CISA 2WPIE 2RHPA 5IKVA 1IQIL 2MGRA 4TGFA 2KV4A 2JKHL 1NPEB 4ISHL 2UWLB 1FFMA 2WPHE 5E8DA 4CUDA 4Y6DB 3HS5A 1DIYA 2XBWL 2P16L 2Y81B 4XL1A 4O1ZA 1EMNA 4AQTA 1K36A 1EMOA 1HAFA 2W2ME 1IQNL 4MMXB 2J2UB 5IKRA 3F1SB 1HT5A 3KRKA 3KCGL 1YUKB 1HRFA 1DVAL 4JYUL 3S6XA 2Y7XB 5JB8E 5KN5C 4Y71B 2W2PE 1FE2A 1UZPA 2FD6A 2MGPA 3FBYA 5K0HB 1IGZA 1CVWL 2UWOB 1DDXA 3Q7DA 2Y5GL 5CKNA 5L2ZL 1NFWB 1YUGA 2VWLL 4Y79B 3N8XA 1ATBA 3TH3L 1Q4GA 1NFUB 1L5GB 2RNLA 4C16A 3SOVA 3TZIA 2WG3C 3GCWE 2I9BA 2W3IB 2H9EL 1EPJA 4JZDL 3U7UG 1KSNB 1LQDA 1CCFA 3HO3A 2W3KB 2EI8B 2WZPP 4D0FA 4D0EA 1IJQA 4Y7AB 1IOEL 1WHEA 1JL9A 1XDTR 1G2LB 3SOBB 4YT7L 1URKA 1CEJA 4FM5A 2WFXB 2WFTA 4NA9L 3NT1A 4CSYA 3N8YA 1IQGL 4YT6L 1LPGA 1YGCL 1HAEA 3HS7A 1LPKA 5KIRA 4X8TL 3LN1A 2AYLA 1FSBA 1YO8A 3LIWB 4BTIA 1BF9A 1IQJL 3LC3B 3HO4A 1OB1C 3KQCL 1G1QA 1J9CL 1JBUL 1EZQB 4MMZB 2XC0L 1B9WA 2WG4B 3NTBA 5JVYA 2EI7B 2WPKE 2YGOA 3CFWA 3BPSE 5JBCE 3OLTA 4E1GA 4JZFL 2PHBB 1I0UA 2MHPA 1LMJA 3SW2A 5IKTA 1IQML 4A7IA 2BQ6A 2Y5HL 2BOUA 4Z0KB 1TPGA 3H5CB 2J95B 3P5BL 4YZUB 4M10A 4CUEA 5JW1A 1N1IA 2BZ6L 4ZH8B 2P95L 2P3FL 2PUQL 2W2OE 1EAIC 1CX2A 3ZYIB 1RFNB 2BO2A 2W86A 1EPIA 3GCXE 1ATEA 4LORA 2J38B 4ZXYL 2B7DL 5CKQA 2GD4A 2OYUP 3N8ZA 3Q3KB 4Z0LA 2KL7A 4COXA 5JBBE 3RR3A 1HCGB 4CUFA 2P3FN 1EGFA 3LTGD 1N7DA 1U8CB 4BXSA 4RUTA 4RRYA 5F1AA 1IQKL 1NQLB 4BXWA 2Q1JB 1EQHA 1W8BL 3ENSA 4A94C 1JV2B 2XC5L 3V65B 1IQLL 2D1JB 2P3TA 3KL6B 3CENL 2KNIA 4D90A 2P94L 3M36L 3M37L 2XBVL 3TGFA 1V3XB 1LPZA 3HO5A 1P0SL 4MMYB 1UZKA 2DDUA 3HPTA 1GK5A 3POYA 1A3PA 5EGMB 2BOHA 1MQ6L 1DX5I 4JZEL 1L3YA 1XFEA 1HX2A 1IQEL 1O5DL 1FJSL 3KQBL 1DQBA 3CS7L 2WYGB 2Y5FL 1CCVA 3N8YB 3IITB 1EPHA 6COXA 1NZIA 1X7AL 2WPME 1FF7A 2VVVL 3GISX 1F0RB 3V64C 3F6UL 2FZZL 2CJIB 3LTFB 2UWPB 3NTGA 1NT0A 1YUFA 2PR3B 3DEMA 5L2YL 4RS0A 1U67A 4X8VL 1HZ8A 3MQEA 2VH6B 4BTTA 2NPRA 4PH9A 2W26B 1UZQA 2VWMK 3N8WA 1PRHA 1QFKL 3LAQA 2BQ7A 2VWOL 2G00L 2BOXA 5COXA 3FFGL 3N8WB 5JVZA 1MOXC 4O02B 4Z6AL 2YGQA 3ZYGA 3FCSB 1F7EA 2I9AA 1P9JA 2WPLE 2RA0L 4RRWA 4BDXA 2VVUL 5F19A 3K9XA 2H9EC 3C9AC 1EQGA 4NG9L 1LMMA 3NJPC 1KLIL 4XLWA 1EPGA 3TK6B 2BQWA 4ZXXL 5IKQA 2BOKL 1TLEA 1HT8A 4X8SL 2J4IB 3SOQA 2P26A 2FLRL 2P93L 1W7XL 2P3UA 4M11A 3ELAL 1APOA 1KLOA 3OLUA 1IQFL 2ADXA 1MQ5L 3QMOA 3EGFA 3KQDL 2K2TA 3PGHA 4OTYA 2VH0B 2BMGA 4JYVL 1IP0A 1PFXL 1NFXB 3CA7A 1APQA 1Z6EL 4X8UL 1FAXL 2KB9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RRX A;  3BT1 A;  1EBV A;  1PGE A;  2K2S B;  2FLG A;  3LN0 A;  2Y82 B;  1ATD A;  1XKB A;  1ATA A;  3ASI A;  1SZB A;  4ZAE B;  3QH0 A;  5CKM A;  3KQE L;  1KIG L;  3R05 A;  1KLJ L;  2VJ3 A;  3MDL A;  1Z6C A;  1ADX A;  4LMF A;  3HS6 A;  2Y80 B;  2XBY L;  2W2Q E;  4BDW A;  5JB9 E;  3KK6 A;  1IGX A;  2J94 B;  2P28 B;  2YGP A;  1F0S B;  1G1T A;  1AUT L;  3TBD A;  4ZHA B;  4Y76 B;  1CVU A;  1NFY B;  3LC5 B;  4XBM A;  2VWN L;  2WPJ E;  1PTH A;  1M1X B;  2XBX L;  4RRZ A;  1COU A;  1IQH L;  1G1R A;  1HRE A;  1UZJ A;  3QCW A;  1PXX A;  4OTJ A;  2XC4 L;  1C5M F;  2Y7Z B;  3BT2 A;  1FAK L;  1F7M A;  3ZYJ B;  1TOZ A;  2OYE P;  2FLB L;  3TK5 B;  4BTU A;  1K37 A;  2WYJ B;  2EI6 B;  5I46 L;  2W2N E;  3IJE B;  4ISI L;  4G1M B;  4Y7B B;  1G2M B;  5JBA E;  3U73 A;  5FDQ A;  3N8V A;  2F9B L;  2M74 A;  1HJ7 A;  2J34 B;  1G1S A;  1CQE A;  4NGA L;  2VVC K;  1IVO C;  2Y38 A;  2TGF A;  1ZAQ A;  1WHF A;  1IOX A;  1WU1 B;  1XKA L;  5L30 L;  5CIS A;  2WPI E;  2RHP A;  5IKV A;  1IQI L;  2MGR A;  4TGF A;  2KV4 A;  2JKH L;  1NPE B;  4ISH L;  2UWL B;  1FFM A;  2WPH E;  5E8D A;  4CUD A;  4Y6D B;  3HS5 A;  1DIY A;  2XBW L;  2P16 L;  2Y81 B;  4XL1 A;  4O1Z A;  1EMN A;  4AQT A;  1K36 A;  1EMO A;  1HAF A;  2W2M E;  1IQN L;  4MMX B;  2J2U B;  5IKR A;  3F1S B;  1HT5 A;  3KRK A;  3KCG L;  1YUK B;  1HRF A;  1DVA L;  4JYU L;  2Y7X B;  5JB8 E;  5KN5 C;  4Y71 B;  2W2P E;  1FE2 A;  1UZP A;  2FD6 A;  2MGP A;  3FBY A;  5K0H B;  1IGZ A;  1CVW L;  2UWO B;  1DDX A;  3Q7D A;  2Y5G L;  5CKN A;  5L2Z L;  1NFW B;  1YUG A;  2VWL L;  4Y79 B;  3N8X A;  1ATB A;  3TH3 L;  1Q4G A;  1NFU B;  1L5G B;  2RNL A;  4C16 A;  3SOV A;  3TZI A;  2WG3 C;  3GCW E;  2I9B A;  2W3I B;  2H9E L;  1EPJ A;  4JZD L;  3U7U G;  1KSN B;  1LQD A;  1CCF A;  3HO3 A;  2W3K B;  2EI8 B;  4D0F A;  4D0E A;  1IJQ A;  4Y7A B;  1IOE L;  1WHE A;  1JL9 A;  1XDT R;  1G2L B;  3SOB B;  4YT7 L;  1URK A;  1CEJ A;  4FM5 A;  2WFX B;  2WFT A;  4NA9 L;  3NT1 A;  4CSY A;  3N8Y A;  1IQG L;  4YT6 L;  1LPG A;  1YGC L;  1HAE A;  3HS7 A;  1LPK A;  5KIR A;  4X8T L;  3LN1 A;  2AYL A;  1FSB A;  1YO8 A;  3LIW B;  4BTI A;  1BF9 A;  1IQJ L;  3LC3 B;  3HO4 A;  1OB1 C;  3KQC L;  1G1Q A;  1J9C L;  1JBU L;  1EZQ B;  4MMZ B;  2XC0 L;  1B9W A;  2WG4 B;  3NTB A;  5JVY A;  2EI7 B;  2WPK E;  2YGO A;  3CFW A;  3BPS E;  5JBC E;  3OLT A;  4E1G A;  4JZF L;  2PHB B;  1I0U A;  2MHP A;  1LMJ A;  3SW2 A;  5IKT A;  1IQM L;  4A7I A;  2BQ6 A;  2Y5H L;  2BOU A;  4Z0K B;  1TPG A;  3H5C B;  2J95 B;  3P5B L;  4YZU B;  4M10 A;  4CUE A;  5JW1 A;  1N1I A;  2BZ6 L;  4ZH8 B;  2P95 L;  2P3F L;  2PUQ L;  2W2O E;  1EAI C;  1CX2 A;  3ZYI B;  1RFN B;  2BO2 A;  2W86 A;  1EPI A;  3GCX E;  1ATE A;  4LOR A;  2J38 B;  4ZXY L;  2B7D L;  5CKQ A;  2GD4 A;  2OYU P;  3N8Z A;  3Q3K B;  4Z0L A;  2KL7 A;  4COX A;  5JBB E;  3RR3 A;  1HCG B;  4CUF A;  2P3F N;  1EGF A;  3LTG D;  1N7D A;  1U8C B;  4BXS A;  4RUT A;  4RRY A;  5F1A A;  1IQK L;  1NQL B;  4BXW A;  2Q1J B;  1EQH A;  1W8B L;  3ENS A;  1JV2 B;  2XC5 L;  3V65 B;  1IQL L;  2D1J B;  2P3T A;  3KL6 B;  3CEN L;  4D90 A;  2P94 L;  3M36 L;  3M37 L;  2XBV L;  3TGF A;  1V3X B;  1LPZ A;  3HO5 A;  1P0S L;  4MMY B;  1UZK A;  2DDU A;  3HPT A;  1GK5 A;  3POY A;  1A3P A;  5EGM B;  2BOH A;  1MQ6 L;  1DX5 I;  4JZE L;  1L3Y A;  1XFE A;  1HX2 A;  1IQE L;  1O5D L;  1FJS L;  3KQB L;  1DQB A;  3CS7 L;  2WYG B;  2Y5F L;  1CCV A;  3N8Y B;  3IIT B;  1EPH A;  6COX A;  1NZI A;  1X7A L;  2WPM E;  1FF7 A;  2VVV L;  3GIS X;  1F0R B;  3V64 C;  3F6U L;  2FZZ L;  2CJI B;  3LTF B;  2UWP B;  3NTG A;  1NT0 A;  1YUF A;  2PR3 B;  3DEM A;  5L2Y L;  4RS0 A;  1U67 A;  4X8V L;  1HZ8 A;  3MQE A;  2VH6 B;  4BTT A;  2NPR A;  4PH9 A;  2W26 B;  1UZQ A;  2VWM K;  3N8W A;  1PRH A;  1QFK L;  3LAQ A;  2BQ7 A;  2VWO L;  2G00 L;  2BOX A;  5COX A;  3FFG L;  3N8W B;  5JVZ A;  1MOX C;  4O02 B;  4Z6A L;  3ZYG A;  3FCS B;  1F7E A;  2I9A A;  1P9J A;  2WPL E;  2RA0 L;  4RRW A;  4BDX A;  2VVU L;  5F19 A;  3K9X A;  3C9A C;  1EQG A;  4NG9 L;  3NJP C;  1KLI L;  4XLW A;  1EPG A;  3TK6 B;  2BQW A;  4ZXX L;  5IKQ A;  2BOK L;  1TLE A;  1HT8 A;  4X8S L;  2J4I B;  3SOQ A;  2P26 A;  2FLR L;  2P93 L;  1W7X L;  2P3U A;  4M11 A;  3ELA L;  1APO A;  1KLO A;  3OLU A;  1IQF L;  2ADX A;  1MQ5 L;  3QMO A;  3EGF A;  3KQD L;  2K2T A;  3PGH A;  4OTY A;  2VH0 B;  2BMG A;  4JYV L;  1IP0 A;  1PFX L;  1NFX B;  3CA7 A;  1APQ A;  1Z6E L;  4X8U L;  1FAX L;  2KB9 A; 
#chains in the Genus database with same CATH topology
 4RRX A;  3BT1 A;  1EBV A;  1PGE A;  2K2S B;  2FLG A;  3LN0 A;  2Y82 B;  1ATD A;  1XKB A;  1ATA A;  3ASI A;  1SZB A;  4ZAE B;  3QH0 A;  5CKM A;  3KQE L;  1KIG L;  3R05 A;  4GU3 A;  1KLJ L;  2BSF A;  2VJ3 A;  3MDL A;  1Z6C A;  1ADX A;  4LMF A;  3HS6 A;  2Y80 B;  2XBY L;  2W2Q E;  4BDW A;  5JB9 E;  1V1I A;  3KK6 A;  1IGX A;  2J94 B;  2P28 B;  2YGP A;  1F0S B;  1G1T A;  1AUT L;  3TBD A;  4ZHA B;  1V1H A;  4Y76 B;  1CVU A;  1NFY B;  3LC5 B;  4XBM A;  2VWN L;  2WPJ E;  1PTH A;  1M1X B;  2XBX L;  4RRZ A;  1COU A;  1IQH L;  1G1R A;  1HRE A;  1UZJ A;  3QCW A;  1PXX A;  4OTJ A;  2XC4 L;  1C5M F;  2Y7Z B;  3BT2 A;  1FAK L;  1F7M A;  3ZYJ B;  1TOZ A;  2OYE P;  2FLB L;  3TK5 B;  4BTU A;  1K37 A;  2WYJ B;  2EI6 B;  5I46 L;  2W2N E;  3IJE B;  4ISI L;  4G1M B;  4Y7B B;  1G2M B;  5JBA E;  3U73 A;  5FDQ A;  3N8V A;  2F9B L;  2M74 A;  1HJ7 A;  2J34 B;  1G1S A;  1CQE A;  4NGA L;  2VVC K;  1IVO C;  2Y38 A;  2TGF A;  1ZAQ A;  1WHF A;  1IOX A;  1WU1 B;  1XKA L;  5L30 L;  5CIS A;  2WPI E;  2RHP A;  5IKV A;  1IQI L;  2MGR A;  4TGF A;  2KV4 A;  2JKH L;  1NPE B;  4ISH L;  2UWL B;  1FFM A;  2WPH E;  5E8D A;  4CUD A;  4Y6D B;  3HS5 A;  1DIY A;  2XBW L;  2VRS A;  2P16 L;  2Y81 B;  4XL1 A;  4O1Z A;  1EMN A;  4AQT A;  1K36 A;  1EMO A;  1HAF A;  2W2M E;  1IQN L;  4MMX B;  2J2U B;  5IKR A;  3F1S B;  1HT5 A;  3KRK A;  3KCG L;  1YUK B;  1HRF A;  1DVA L;  4JYU L;  3S6X A;  2Y7X B;  5JB8 E;  5KN5 C;  4Y71 B;  2W2P E;  1FE2 A;  1UZP A;  2FD6 A;  2MGP A;  3FBY A;  5K0H B;  1IGZ A;  1CVW L;  2UWO B;  1DDX A;  1KKE A;  3Q7D A;  2Y5G L;  5CKN A;  5L2Z L;  1NFW B;  1YUG A;  2VWL L;  4Y79 B;  3N8X A;  1ATB A;  3TH3 L;  1Q4G A;  1NFU B;  1L5G B;  2BT8 A;  2RNL A;  4C16 A;  3SOV A;  3TZI A;  2WG3 C;  3GCW E;  2I9B A;  2W3I B;  2H9E L;  1EPJ A;  4JZD L;  3U7U G;  1KSN B;  1LQD A;  1CCF A;  3HO3 A;  2W3K B;  4GU4 A;  2EI8 B;  2WZP P;  4D0F A;  4D0E A;  1IJQ A;  4Y7A B;  1IOE L;  1WHE A;  1JL9 A;  1XDT R;  1G2L B;  3SOB B;  4YT7 L;  1URK A;  1CEJ A;  4FM5 A;  2WFX B;  2WFT A;  4NA9 L;  3NT1 A;  4CSY A;  3N8Y A;  1IQG L;  4YT6 L;  1LPG A;  1YGC L;  2HOR A;  1HAE A;  3HS7 A;  1LPK A;  5KIR A;  4X8T L;  3LN1 A;  2AYL A;  1FSB A;  1YO8 A;  3LIW B;  4BTI A;  1BF9 A;  1IQJ L;  3LC3 B;  3HO4 A;  1OB1 C;  3KQC L;  1LK9 A;  1G1Q A;  2HOX A;  1J9C L;  1JBU L;  1EZQ B;  4MMZ B;  2XC0 L;  1B9W A;  2WG4 B;  3NTB A;  5JVY A;  2EI7 B;  2WPK E;  2YGO A;  3CFW A;  3BPS E;  5JBC E;  3OLT A;  4E1G A;  4JZF L;  2PHB B;  1I0U A;  2MHP A;  1LMJ A;  3SW2 A;  5IKT A;  1IQM L;  4A7I A;  2BQ6 A;  2Y5H L;  2BOU A;  4Z0K B;  1TPG A;  3H5C B;  2J95 B;  3P5B L;  4YZU B;  4M10 A;  4CUE A;  5JW1 A;  1N1I A;  2BZ6 L;  4ZH8 B;  1QIU A;  2P95 L;  2P3F L;  2PUQ L;  2W2O E;  1EAI C;  1CX2 A;  3ZYI B;  1RFN B;  2BO2 A;  2W86 A;  1EPI A;  3GCX E;  1ATE A;  4LOR A;  2J38 B;  4ZXY L;  2B7D L;  5CKQ A;  2GD4 A;  2OYU P;  3N8Z A;  3Q3K B;  4Z0L A;  2KL7 A;  4COX A;  5JBB E;  3RR3 A;  1HCG B;  4CUF A;  2P3F N;  1EGF A;  3LTG D;  1N7D A;  1U8C B;  4BXS A;  4RUT A;  4RRY A;  5F1A A;  1IQK L;  1NQL B;  4BXW A;  2Q1J B;  1EQH A;  1W8B L;  3ENS A;  4A94 C;  1JV2 B;  2XC5 L;  3V65 B;  1IQL L;  2D1J B;  2P3T A;  3KL6 B;  3CEN L;  2KNI A;  4D90 A;  2P94 L;  3M36 L;  3M37 L;  2XBV L;  3TGF A;  1V3X B;  1LPZ A;  3HO5 A;  1P0S L;  4MMY B;  1UZK A;  2DDU A;  3HPT A;  1GK5 A;  3POY A;  1A3P A;  5EGM B;  2JJL A;  2BOH A;  1MQ6 L;  1DX5 I;  4JZE L;  1L3Y A;  1XFE A;  1HX2 A;  1IQE L;  1O5D L;  1FJS L;  3KQB L;  1DQB A;  3CS7 L;  2WYG B;  2Y5F L;  1CCV A;  3N8Y B;  3IIT B;  1EPH A;  6COX A;  1NZI A;  1X7A L;  2WPM E;  1FF7 A;  2VVV L;  3GIS X;  1F0R B;  3V64 C;  3F6U L;  2FZZ L;  2CJI B;  3LTF B;  2UWP B;  3NTG A;  1NT0 A;  1YUF A;  2PR3 B;  3DEM A;  5L2Y L;  4RS0 A;  1U67 A;  4X8V L;  1HZ8 A;  3MQE A;  2VH6 B;  4BTT A;  2NPR A;  4PH9 A;  2W26 B;  1UZQ A;  2VWM K;  3N8W A;  1PRH A;  1QFK L;  3LAQ A;  2BQ7 A;  2VWO L;  2G00 L;  2BOX A;  5COX A;  3FFG L;  3N8W B;  5JVZ A;  1MOX C;  4O02 B;  4Z6A L;  2YGQ A;  3ZYG A;  3FCS B;  1F7E A;  2I9A A;  1P9J A;  2WPL E;  2RA0 L;  4RRW A;  4BDX A;  2VVU L;  5F19 A;  3K9X A;  2H9E C;  3C9A C;  1EQG A;  4NG9 L;  1LMM A;  3NJP C;  1KLI L;  4XLW A;  1EPG A;  3TK6 B;  2BQW A;  4ZXX L;  5IKQ A;  2BOK L;  1TLE A;  1HT8 A;  4X8S L;  2J4I B;  3SOQ A;  2P26 A;  2FLR L;  2P93 L;  1W7X L;  2P3U A;  4M11 A;  3ELA L;  1APO A;  1KLO A;  3OLU A;  1IQF L;  2ADX A;  1MQ5 L;  3QMO A;  3EGF A;  3KQD L;  2K2T A;  3PGH A;  4OTY A;  2VH0 B;  2BMG A;  4JYV L;  1IP0 A;  1PFX L;  2BT7 A;  1NFX B;  3CA7 A;  1APQ A;  1Z6E L;  4X8U L;  1FAX L;  2KB9 A; 
#chains in the Genus database with same CATH homology
 4RRX A;  3BT1 A;  1EBV A;  1PGE A;  2K2S B;  2FLG A;  3LN0 A;  2Y82 B;  1ATD A;  1XKB A;  1ATA A;  3ASI A;  1SZB A;  4ZAE B;  3QH0 A;  5CKM A;  3KQE L;  1KIG L;  3R05 A;  1KLJ L;  2VJ3 A;  3MDL A;  1Z6C A;  1ADX A;  4LMF A;  3HS6 A;  2Y80 B;  2XBY L;  2W2Q E;  4BDW A;  5JB9 E;  3KK6 A;  1IGX A;  2J94 B;  2P28 B;  2YGP A;  1F0S B;  1G1T A;  1AUT L;  3TBD A;  4ZHA B;  4Y76 B;  1CVU A;  1NFY B;  3LC5 B;  4XBM A;  2VWN L;  2WPJ E;  1PTH A;  1M1X B;  2XBX L;  4RRZ A;  1COU A;  1IQH L;  1G1R A;  1HRE A;  1UZJ A;  3QCW A;  1PXX A;  4OTJ A;  2XC4 L;  1C5M F;  2Y7Z B;  3BT2 A;  1FAK L;  1F7M A;  3ZYJ B;  1TOZ A;  2OYE P;  2FLB L;  3TK5 B;  4BTU A;  1K37 A;  2WYJ B;  2EI6 B;  5I46 L;  2W2N E;  3IJE B;  4ISI L;  4G1M B;  4Y7B B;  1G2M B;  5JBA E;  3U73 A;  5FDQ A;  3N8V A;  2F9B L;  2M74 A;  1HJ7 A;  2J34 B;  1G1S A;  1CQE A;  4NGA L;  2VVC K;  1IVO C;  2Y38 A;  2TGF A;  1ZAQ A;  1WHF A;  1IOX A;  1WU1 B;  1XKA L;  5L30 L;  5CIS A;  2WPI E;  2RHP A;  5IKV A;  1IQI L;  2MGR A;  4TGF A;  2KV4 A;  2JKH L;  1NPE B;  4ISH L;  2UWL B;  1FFM A;  2WPH E;  5E8D A;  4CUD A;  4Y6D B;  3HS5 A;  1DIY A;  2XBW L;  2P16 L;  2Y81 B;  4XL1 A;  4O1Z A;  1EMN A;  4AQT A;  1K36 A;  1EMO A;  1HAF A;  2W2M E;  1IQN L;  4MMX B;  2J2U B;  5IKR A;  3F1S B;  1HT5 A;  3KRK A;  3KCG L;  1YUK B;  1HRF A;  1DVA L;  4JYU L;  3S6X A;  2Y7X B;  5JB8 E;  5KN5 C;  4Y71 B;  2W2P E;  1FE2 A;  1UZP A;  2FD6 A;  2MGP A;  3FBY A;  5K0H B;  1IGZ A;  1CVW L;  2UWO B;  1DDX A;  3Q7D A;  2Y5G L;  5CKN A;  5L2Z L;  1NFW B;  1YUG A;  2VWL L;  4Y79 B;  3N8X A;  1ATB A;  3TH3 L;  1Q4G A;  1NFU B;  1L5G B;  2RNL A;  4C16 A;  3SOV A;  3TZI A;  2WG3 C;  3GCW E;  2I9B A;  2W3I B;  2H9E L;  1EPJ A;  4JZD L;  3U7U G;  1KSN B;  1LQD A;  1CCF A;  3HO3 A;  2W3K B;  2EI8 B;  2WZP P;  4D0F A;  4D0E A;  1IJQ A;  4Y7A B;  1IOE L;  1WHE A;  1JL9 A;  1XDT R;  1G2L B;  3SOB B;  4YT7 L;  1URK A;  1CEJ A;  4FM5 A;  2WFX B;  2WFT A;  4NA9 L;  3NT1 A;  4CSY A;  3N8Y A;  1IQG L;  4YT6 L;  1LPG A;  1YGC L;  1HAE A;  3HS7 A;  1LPK A;  5KIR A;  4X8T L;  3LN1 A;  2AYL A;  1FSB A;  1YO8 A;  3LIW B;  4BTI A;  1BF9 A;  1IQJ L;  3LC3 B;  3HO4 A;  1OB1 C;  3KQC L;  1G1Q A;  1J9C L;  1JBU L;  1EZQ B;  4MMZ B;  2XC0 L;  1B9W A;  2WG4 B;  3NTB A;  5JVY A;  2EI7 B;  2WPK E;  2YGO A;  3CFW A;  3BPS E;  5JBC E;  3OLT A;  4E1G A;  4JZF L;  2PHB B;  1I0U A;  2MHP A;  1LMJ A;  3SW2 A;  5IKT A;  1IQM L;  4A7I A;  2BQ6 A;  2Y5H L;  2BOU A;  4Z0K B;  1TPG A;  3H5C B;  2J95 B;  3P5B L;  4YZU B;  4M10 A;  4CUE A;  5JW1 A;  1N1I A;  2BZ6 L;  4ZH8 B;  2P95 L;  2P3F L;  2PUQ L;  2W2O E;  1EAI C;  1CX2 A;  3ZYI B;  1RFN B;  2BO2 A;  2W86 A;  1EPI A;  3GCX E;  1ATE A;  4LOR A;  2J38 B;  4ZXY L;  2B7D L;  5CKQ A;  2GD4 A;  2OYU P;  3N8Z A;  3Q3K B;  4Z0L A;  2KL7 A;  4COX A;  5JBB E;  3RR3 A;  1HCG B;  4CUF A;  2P3F N;  1EGF A;  3LTG D;  1N7D A;  1U8C B;  4BXS A;  4RUT A;  4RRY A;  5F1A A;  1IQK L;  1NQL B;  4BXW A;  2Q1J B;  1EQH A;  1W8B L;  3ENS A;  4A94 C;  1JV2 B;  2XC5 L;  3V65 B;  1IQL L;  2D1J B;  2P3T A;  3KL6 B;  3CEN L;  2KNI A;  4D90 A;  2P94 L;  3M36 L;  3M37 L;  2XBV L;  3TGF A;  1V3X B;  1LPZ A;  3HO5 A;  1P0S L;  4MMY B;  1UZK A;  2DDU A;  3HPT A;  1GK5 A;  3POY A;  1A3P A;  5EGM B;  2BOH A;  1MQ6 L;  1DX5 I;  4JZE L;  1L3Y A;  1XFE A;  1HX2 A;  1IQE L;  1O5D L;  1FJS L;  3KQB L;  1DQB A;  3CS7 L;  2WYG B;  2Y5F L;  1CCV A;  3N8Y B;  3IIT B;  1EPH A;  6COX A;  1NZI A;  1X7A L;  2WPM E;  1FF7 A;  2VVV L;  3GIS X;  1F0R B;  3V64 C;  3F6U L;  2FZZ L;  2CJI B;  3LTF B;  2UWP B;  3NTG A;  1NT0 A;  1YUF A;  2PR3 B;  3DEM A;  5L2Y L;  4RS0 A;  1U67 A;  4X8V L;  1HZ8 A;  3MQE A;  2VH6 B;  4BTT A;  2NPR A;  4PH9 A;  2W26 B;  1UZQ A;  2VWM K;  3N8W A;  1PRH A;  1QFK L;  3LAQ A;  2BQ7 A;  2VWO L;  2G00 L;  2BOX A;  5COX A;  3FFG L;  3N8W B;  5JVZ A;  1MOX C;  4O02 B;  4Z6A L;  2YGQ A;  3ZYG A;  3FCS B;  1F7E A;  2I9A A;  1P9J A;  2WPL E;  2RA0 L;  4RRW A;  4BDX A;  2VVU L;  5F19 A;  3K9X A;  2H9E C;  3C9A C;  1EQG A;  4NG9 L;  1LMM A;  3NJP C;  1KLI L;  4XLW A;  1EPG A;  3TK6 B;  2BQW A;  4ZXX L;  5IKQ A;  2BOK L;  1TLE A;  1HT8 A;  4X8S L;  2J4I B;  3SOQ A;  2P26 A;  2FLR L;  2P93 L;  1W7X L;  2P3U A;  4M11 A;  3ELA L;  1APO A;  1KLO A;  3OLU A;  1IQF L;  2ADX A;  1MQ5 L;  3QMO A;  3EGF A;  3KQD L;  2K2T A;  3PGH A;  4OTY A;  2VH0 B;  2BMG A;  4JYV L;  1IP0 A;  1PFX L;  1NFX B;  3CA7 A;  1APQ A;  1Z6E L;  4X8U L;  1FAX L;  2KB9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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