5KN5C

Tgfalpha/epiregulin complex with neutralizing antibody ly3016859
Total Genus 5

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
40
structure length
40
Chain Sequence
DSHTQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYS2 (29-34)TIV2 (24-27)S1 (19-24)S3 (38-39)TI1 (25-28)TI2 (40-43)TII1 (35-38)Updating...
connected with : NaN
molecule tags Immune system
source organism Homo sapiens
publication title Structural basis of selectivity and neutralizing activity of a TGF alpha /epiregulin specific antibody.
pubmed doi rcsb
molecule keywords Epiregulin Antibody LY3016859 Fab Heavy Chain
total genus 5
structure length 40
sequence length 40
chains with identical sequence F
ec nomenclature
pdb deposition date 2016-06-27
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 5kn5C00
3IITB 1CX2A 4OTJA 2GD4A 4LMFA 1EGFA 3KL6B 5IKQA 1GK5A 2RA0L 1HCGB 2WYGB 1ZAQA 1HREA 2BQ7A 1BF9A 3N8VA 4RS0A 4ISHL 1HZ8A 1YUGA 1APOA 1EQGA 4COXA 4RRXA 2W86A 1XKBA 4RRZA 5IKTA 3ZYGA 3OLTA 1NFWB 1XKAL 2FLRL 1KIGL 1IQKL 5L2ZL 2P26A 2WPIE 4JZEL 5KIRA 3TBDA 3U7UG 4XLWA 2BOHA 1DDXA 5JBAE 2XBXL 4XL1A 4MMZB 2P93L 4NGAL 3TZIA 3PGHA 1AUTL 2WG3C 1CVUA 4BDWA 4LORA 1L5GB 3P5BL 1NFYB 1TLEA 2RHPA 1NPEB 3LN0A 5E8DA 1LPKA 2PR3B 1EAIC 2BOKL 2BQWA 1WU1B 2KB9A 4OTYA 2OYUP 2W3KB 3CA7A 1A3PA 1DX5I 2G00L 2K2TA 1W8BL 4A7IA 1P0SL 1P9JA 2WYJB 2FLBL 5F19A 2PHBB 1UZKA 1UZQA 2XC0L 3KQBL 1FF7A 4Z0KB 2WPKE 5IKVA 4ISIL 1C5MF 5IKRA 4D0FA 5JBBE 1HRFA 2P3UA 4TGFA 1JBUL 5JVYA 2W2QE 4JZDL 2EI8B 2WPME 3MQEA 2AYLA 5FDQA 2ADXA 2Y5FL 1LPZA 1IJQA 3EGFA 1NT0A 2VH6B 1EPHA 1FFMA 4CUDA 1DIYA 1EPIA 1QFKL 2I9BA 4Y7BB 2K2SB 2WFXB 3KQEL 3LC3B 4ZAEB 5EGMB 2OYEP 1HAEA 3SW2A 3KQDL 3N8XA 4XBMA 4X8VL 2WPLE 4JYUL 3KK6A 3QMOA 3LN1A 3N8WA 4Z0LA 1CQEA 3CENL 1KSNB 5JVZA 2VWOL 3GCXE 1PGEA 1B9WA 1Q4GA 4E1GA 3H5CB 1G1TA 3N8YA 4ZXXL 3FBYA 1HT5A 1KLJL 1U8CB 3LAQA 3HS5A 1UZJA 5CKQA 1F0SB 1LMJA 3NJPC 6COXA 3KCGL 1PRHA 1YGCL 1XFEA 3SOBB 1IOEL 4D90A 4ZXYL 1CCFA 5CKMA 5CISA 4MMYB 4BXWA 1FE2A 3HO5A 4Y7AB 1WHEA 2Q1JB 1F7MA 1G2MB 5COXA 1MQ5L 1W7XL 5I46L 1L3YA 3N8WB 5JB8E 1O5DL 1EPJA 1FSBA 1NFXB 1YO8A 4YT7L 5JB9E 4FM5A 1G1SA 1URKA 2J38B 1HX2A 3HO3A 2Y7XB 2BZ6L 2Y80B 1ATAA 1YUKB 4X8UL 4BXSA 3N8YB 1RFNB 4BDXA 2VWMK 4JYVL 2PUQL 1IQFL 2YGPA 1DVAL 4PH9A 4M10A 1HAFA 3Q3KB 4M11A 2W2ME 4AQTA 2J95B 2TGFA 3Q7DA 3QH0A 2Y81B 2W2PE 2W3IB 5L30L 2UWPB 3GISX 2W2NE 1IGZA 1EBVA 3K9XA 2XBWL 1XDTR 2BQ6A 2WPJE 3TGFA 1G1RA 4YZUB 1APQA 4Y76B 3NT1A 4Z6AL 1LPGA 1N1IA 2VWLL 3R05A 3NTBA 2P16L 2J34B 3CS7L 3LIWB 2P94L 1OB1C 4MMXB 3GCWE 2VH0B 3OLUA 1WHFA 1X7AL 1UZPA 2XBVL 1LQDA 1FJSL 2EI7B 3TK6B 3TH3L 2Y5HL 4X8SL 2WPHE 2WG4B 4RRYA 3FCSB 4RUTA 1DQBA 3RR3A 2KV4A 5F1AA 1EMNA 1IP0A 2BMGA 1IGXA 1TOZA 2UWLB 2NPRA 2FLGA 3HO4A 4ZH8B 2XBYL 2VVVL 1IVOC 3BPSE 5JBCE 4ZHAB 1IQML 3LC5B 2W26B 1PFXL 2WFTA 2JKHL 2BOXA 3F1SB 3KRKA 1IQHL 1I0UA 2MGRA 1COUA 3V64C 3KQCL 4C16A 3FFGL 5K0HB 1SZBA 2UWOB 2P95L 1EZQB 2W2OE 1CVWL 4X8TL 1PTHA 1ATDA 1FAXL 2FD6A 2P3TA 3DEMA 3M36L 3HS7A 1EQHA 4YT6L 4RRWA 2BOUA 1IQEL 2Y5GL 5CKNA 4BTTA 1N7DA 3SOQA 5KN5C 2F9BL 3F6UL 1IQJL 1K36A 2J2UB 3ZYIB 1EPGA 1NFUB 4CUFA 1CCVA 2M74A 2MGPA 4G1MB 3LTGD 2D1JB 2P3FN 4Y79B 2MHPA 1M1XB 2BO2A 1K37A 2VVCK 1KLIL 1F7EA 1J9CL 1YUFA 1IQGL 1NZIA 3NTGA 1U67A 1TPGA 1ATEA 2CJIB 4NG9L 2Y82B 3HS6A 4BTIA 1HJ7A 1EMOA 1Z6EL 2XC5L 3BT2A 1V3XB 3HPTA 2Y38A 2RNLA 4D0EA 2B7DL 2DDUA 1MQ6L 1KLOA 2VWNL 1IQIL 1NQLB 3N8ZA 4O02B 1IOXA 1CEJA 2Y7ZB 1F0RB 2P28B 1JL9A 3POYA 2KL7A 3ZYJB 3SOVA 1MOXC 1G1QA 4CSYA 2VVUL 3IJEB 2J4IB 1ATBA 1FAKL 3C9AC 1JV2B 4CUEA 2FZZL 2I9AA 3ELAL 5JW1A 2J94B 3CFWA 3ENSA 3BT1A 3U73A 4O1ZA 1G2LB 2P3FL 1PXXA 1IQLL 2EI6B 3M37L 1Z6CA 3QCWA 4Y71B 2YGOA 1ADXA 3LTFB 4NA9L 4JZFL 4BTUA 3V65B 1IQNL 3TK5B 5L2YL 4Y6DB 2XC4L 1HT8A 3MDLA 3ASIA 2H9EL 2VJ3A
chains in the Genus database with same CATH superfamily
3IITB 1CX2A 4OTJA 2GD4A 4LMFA 1EGFA 3KL6B 5IKQA 1GK5A 2RA0L 1HCGB 2WYGB 1ZAQA 1HREA 2BQ7A 1BF9A 3N8VA 4RS0A 4ISHL 1HZ8A 1YUGA 1APOA 1EQGA 4COXA 4RRXA 2W86A 1XKBA 4RRZA 5IKTA 3ZYGA 3OLTA 1NFWB 1XKAL 2FLRL 1KIGL 1IQKL 5L2ZL 2P26A 2WPIE 4JZEL 5KIRA 3TBDA 3U7UG 4XLWA 2BOHA 1DDXA 5JBAE 2XBXL 4XL1A 4MMZB 2P93L 4NGAL 3TZIA 3PGHA 1AUTL 2WG3C 1CVUA 4BDWA 4LORA 1L5GB 3P5BL 1NFYB 1TLEA 2RHPA 1NPEB 3LN0A 5E8DA 1LPKA 2PR3B 1EAIC 2BOKL 2BQWA 1WU1B 2KB9A 4OTYA 2OYUP 2W3KB 3CA7A 1A3PA 1DX5I 2G00L 2K2TA 1W8BL 4A7IA 1P0SL 1V1HA 1P9JA 2WYJB 2FLBL 5F19A 1KKEA 2PHBB 1UZKA 1UZQA 2XC0L 3KQBL 1FF7A 4Z0KB 2WPKE 5IKVA 2H9EC 4ISIL 1C5MF 5IKRA 4D0FA 5JBBE 2BT7A 1HRFA 2P3UA 4TGFA 1JBUL 5JVYA 2W2QE 4JZDL 2EI8B 2WPME 3MQEA 2AYLA 5FDQA 2ADXA 2Y5FL 1LPZA 1IJQA 3EGFA 1NT0A 2VRSA 2VH6B 1EPHA 2YGQA 1FFMA 4CUDA 1DIYA 1EPIA 1QFKL 2I9BA 4Y7BB 2K2SB 2WFXB 3KQEL 3LC3B 4ZAEB 5EGMB 2OYEP 1HAEA 3SW2A 3KQDL 3N8XA 4XBMA 4X8VL 2WPLE 4JYUL 3KK6A 3QMOA 3LN1A 3N8WA 4Z0LA 1CQEA 2BSFA 3CENL 1KSNB 5JVZA 2VWOL 3GCXE 1PGEA 4GU4A 1B9WA 1Q4GA 4E1GA 3H5CB 1G1TA 3N8YA 4ZXXL 3FBYA 1HT5A 1KLJL 1U8CB 3LAQA 3HS5A 1UZJA 5CKQA 1F0SB 1LMJA 3NJPC 6COXA 3KCGL 1PRHA 1YGCL 1XFEA 3SOBB 1IOEL 4D90A 4ZXYL 1CCFA 5CKMA 5CISA 4MMYB 4BXWA 1FE2A 3HO5A 4Y7AB 1WHEA 2Q1JB 1F7MA 1G2MB 5COXA 1MQ5L 1W7XL 5I46L 1L3YA 3N8WB 5JB8E 1O5DL 1EPJA 1FSBA 1NFXB 1YO8A 4YT7L 5JB9E 4FM5A 1G1SA 1URKA 2J38B 1HX2A 3HO3A 2Y7XB 2BZ6L 2Y80B 1ATAA 1YUKB 4X8UL 4BXSA 3N8YB 1RFNB 4BDXA 2VWMK 4JYVL 2PUQL 1IQFL 2YGPA 2WZPP 1DVAL 4PH9A 4M10A 1HAFA 3Q3KB 4M11A 2W2ME 4AQTA 2J95B 2TGFA 3Q7DA 3QH0A 2Y81B 2W2PE 2W3IB 5L30L 2UWPB 3GISX 3S6XA 2W2NE 1IGZA 1EBVA 3K9XA 2XBWL 1XDTR 2BQ6A 2WPJE 3TGFA 1G1RA 4YZUB 1APQA 4Y76B 3NT1A 4Z6AL 1LPGA 1N1IA 2VWLL 3R05A 3NTBA 2P16L 2J34B 3CS7L 3LIWB 2P94L 1OB1C 4MMXB 3GCWE 2VH0B 2JJLA 3OLUA 1WHFA 1X7AL 1UZPA 2XBVL 1LQDA 1FJSL 2EI7B 3TK6B 3TH3L 2Y5HL 4X8SL 2WPHE 2WG4B 4RRYA 3FCSB 4RUTA 1DQBA 4GU3A 3RR3A 2KV4A 5F1AA 1EMNA 1IP0A 2BMGA 1IGXA 1TOZA 2UWLB 2NPRA 2FLGA 3HO4A 4ZH8B 2HORA 2XBYL 2VVVL 1IVOC 3BPSE 5JBCE 4ZHAB 1IQML 3LC5B 2W26B 1PFXL 2WFTA 2JKHL 2BOXA 3F1SB 3KRKA 1IQHL 1I0UA 2MGRA 1COUA 1LK9A 3V64C 3KQCL 1LMMA 1QIUA 4C16A 3FFGL 5K0HB 1SZBA 2UWOB 2P95L 1EZQB 2W2OE 1CVWL 4X8TL 1PTHA 1ATDA 1FAXL 2FD6A 2P3TA 3DEMA 3M36L 3HS7A 1EQHA 4YT6L 4RRWA 2BOUA 1IQEL 2Y5GL 5CKNA 4BTTA 1N7DA 3SOQA 5KN5C 2F9BL 3F6UL 1IQJL 1K36A 2J2UB 3ZYIB 1EPGA 1NFUB 4CUFA 1CCVA 2M74A 2MGPA 4G1MB 3LTGD 2D1JB 2P3FN 4Y79B 2MHPA 2BT8A 1M1XB 2BO2A 1K37A 2VVCK 1KLIL 1F7EA 1J9CL 1YUFA 1IQGL 1NZIA 3NTGA 1U67A 1TPGA 1ATEA 2CJIB 4NG9L 2Y82B 3HS6A 4A94C 4BTIA 1HJ7A 2HOXA 1EMOA 1Z6EL 2XC5L 3BT2A 1V3XB 3HPTA 2Y38A 2RNLA 4D0EA 2B7DL 2DDUA 1MQ6L 1KLOA 2VWNL 1IQIL 1NQLB 3N8ZA 4O02B 1IOXA 1CEJA 2Y7ZB 1F0RB 2P28B 1JL9A 3POYA 2KL7A 3ZYJB 3SOVA 1MOXC 1G1QA 2KNIA 4CSYA 2VVUL 3IJEB 2J4IB 1ATBA 1FAKL 3C9AC 1JV2B 4CUEA 2FZZL 2I9AA 3ELAL 5JW1A 2J94B 3CFWA 3ENSA 3BT1A 3U73A 4O1ZA 1G2LB 2P3FL 1PXXA 1IQLL 2EI6B 3M37L 1Z6CA 3QCWA 4Y71B 2YGOA 1ADXA 1V1IA 3LTFB 4NA9L 4JZFL 4BTUA 3V65B 1IQNL 3TK5B 5L2YL 4Y6DB 2XC4L 1HT8A 3MDLA 3ASIA 2H9EL 2VJ3A
chains in the Genus database with same CATH topology
3IITB 1CX2A 4OTJA 2GD4A 4LMFA 1EGFA 3KL6B 5IKQA 1GK5A 2RA0L 1HCGB 2WYGB 1ZAQA 1HREA 2BQ7A 1BF9A 3N8VA 4RS0A 4ISHL 1HZ8A 1YUGA 1APOA 1EQGA 4COXA 4RRXA 2W86A 1XKBA 4RRZA 5IKTA 3ZYGA 3OLTA 1NFWB 1XKAL 2FLRL 1KIGL 1IQKL 5L2ZL 2P26A 2WPIE 4JZEL 5KIRA 3TBDA 3U7UG 4XLWA 2BOHA 1DDXA 5JBAE 2XBXL 4XL1A 4MMZB 2P93L 4NGAL 3TZIA 3PGHA 1AUTL 2WG3C 1CVUA 4BDWA 4LORA 1L5GB 3P5BL 1NFYB 1TLEA 2RHPA 1NPEB 3LN0A 5E8DA 1LPKA 2PR3B 1EAIC 2BOKL 2BQWA 1WU1B 2KB9A 4OTYA 2OYUP 2W3KB 3CA7A 1A3PA 1DX5I 2G00L 2K2TA 1W8BL 4A7IA 1P0SL 1P9JA 2WYJB 2FLBL 5F19A 2PHBB 1UZKA 1UZQA 2XC0L 3KQBL 1FF7A 4Z0KB 2WPKE 5IKVA 2H9EC 4ISIL 1C5MF 5IKRA 4D0FA 5JBBE 1HRFA 2P3UA 4TGFA 1JBUL 5JVYA 2W2QE 4JZDL 2EI8B 2WPME 3MQEA 2AYLA 5FDQA 2ADXA 2Y5FL 1LPZA 1IJQA 3EGFA 1NT0A 2VH6B 1EPHA 2YGQA 1FFMA 4CUDA 1DIYA 1EPIA 1QFKL 2I9BA 4Y7BB 2K2SB 2WFXB 3KQEL 3LC3B 4ZAEB 5EGMB 2OYEP 1HAEA 3SW2A 3KQDL 3N8XA 4XBMA 4X8VL 2WPLE 4JYUL 3KK6A 3QMOA 3LN1A 3N8WA 4Z0LA 1CQEA 3CENL 1KSNB 5JVZA 2VWOL 3GCXE 1PGEA 1B9WA 1Q4GA 4E1GA 3H5CB 1G1TA 3N8YA 4ZXXL 3FBYA 1HT5A 1KLJL 1U8CB 3LAQA 3HS5A 1UZJA 5CKQA 1F0SB 1LMJA 3NJPC 6COXA 3KCGL 1PRHA 1YGCL 1XFEA 3SOBB 1IOEL 4D90A 4ZXYL 1CCFA 5CKMA 5CISA 4MMYB 4BXWA 1FE2A 3HO5A 4Y7AB 1WHEA 2Q1JB 1F7MA 1G2MB 5COXA 1MQ5L 1W7XL 5I46L 1L3YA 3N8WB 5JB8E 1O5DL 1EPJA 1FSBA 1NFXB 1YO8A 4YT7L 5JB9E 4FM5A 1G1SA 1URKA 2J38B 1HX2A 3HO3A 2Y7XB 2BZ6L 2Y80B 1ATAA 1YUKB 4X8UL 4BXSA 3N8YB 1RFNB 4BDXA 2VWMK 4JYVL 2PUQL 1IQFL 2YGPA 2WZPP 1DVAL 4PH9A 4M10A 1HAFA 3Q3KB 4M11A 2W2ME 4AQTA 2J95B 2TGFA 3Q7DA 3QH0A 2Y81B 2W2PE 2W3IB 5L30L 2UWPB 3GISX 3S6XA 2W2NE 1IGZA 1EBVA 3K9XA 2XBWL 1XDTR 2BQ6A 2WPJE 3TGFA 1G1RA 4YZUB 1APQA 4Y76B 3NT1A 4Z6AL 1LPGA 1N1IA 2VWLL 3R05A 3NTBA 2P16L 2J34B 3CS7L 3LIWB 2P94L 1OB1C 4MMXB 3GCWE 2VH0B 3OLUA 1WHFA 1X7AL 1UZPA 2XBVL 1LQDA 1FJSL 2EI7B 3TK6B 3TH3L 2Y5HL 4X8SL 2WPHE 2WG4B 4RRYA 3FCSB 4RUTA 1DQBA 3RR3A 2KV4A 5F1AA 1EMNA 1IP0A 2BMGA 1IGXA 1TOZA 2UWLB 2NPRA 2FLGA 3HO4A 4ZH8B 2XBYL 2VVVL 1IVOC 3BPSE 5JBCE 4ZHAB 1IQML 3LC5B 2W26B 1PFXL 2WFTA 2JKHL 2BOXA 3F1SB 3KRKA 1IQHL 1I0UA 2MGRA 1COUA 3V64C 3KQCL 1LMMA 4C16A 3FFGL 5K0HB 1SZBA 2UWOB 2P95L 1EZQB 2W2OE 1CVWL 4X8TL 1PTHA 1ATDA 1FAXL 2FD6A 2P3TA 3DEMA 3M36L 3HS7A 1EQHA 4YT6L 4RRWA 2BOUA 1IQEL 2Y5GL 5CKNA 4BTTA 1N7DA 3SOQA 5KN5C 2F9BL 3F6UL 1IQJL 1K36A 2J2UB 3ZYIB 1EPGA 1NFUB 4CUFA 1CCVA 2M74A 2MGPA 4G1MB 3LTGD 2D1JB 2P3FN 4Y79B 2MHPA 1M1XB 2BO2A 1K37A 2VVCK 1KLIL 1F7EA 1J9CL 1YUFA 1IQGL 1NZIA 3NTGA 1U67A 1TPGA 1ATEA 2CJIB 4NG9L 2Y82B 3HS6A 4A94C 4BTIA 1HJ7A 1EMOA 1Z6EL 2XC5L 3BT2A 1V3XB 3HPTA 2Y38A 2RNLA 4D0EA 2B7DL 2DDUA 1MQ6L 1KLOA 2VWNL 1IQIL 1NQLB 3N8ZA 4O02B 1IOXA 1CEJA 2Y7ZB 1F0RB 2P28B 1JL9A 3POYA 2KL7A 3ZYJB 3SOVA 1MOXC 1G1QA 2KNIA 4CSYA 2VVUL 3IJEB 2J4IB 1ATBA 1FAKL 3C9AC 1JV2B 4CUEA 2FZZL 2I9AA 3ELAL 5JW1A 2J94B 3CFWA 3ENSA 3BT1A 3U73A 4O1ZA 1G2LB 2P3FL 1PXXA 1IQLL 2EI6B 3M37L 1Z6CA 3QCWA 4Y71B 2YGOA 1ADXA 3LTFB 4NA9L 4JZFL 4BTUA 3V65B 1IQNL 3TK5B 5L2YL 4Y6DB 2XC4L 1HT8A 3MDLA 3ASIA 2H9EL 2VJ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IIT B;  1CX2 A;  4OTJ A;  2GD4 A;  4LMF A;  1EGF A;  3KL6 B;  5IKQ A;  1GK5 A;  2RA0 L;  1HCG B;  2WYG B;  1ZAQ A;  1HRE A;  2BQ7 A;  1BF9 A;  3N8V A;  4RS0 A;  4ISH L;  1HZ8 A;  1YUG A;  1APO A;  1EQG A;  4COX A;  4RRX A;  2W86 A;  1XKB A;  4RRZ A;  5IKT A;  3ZYG A;  3OLT A;  1NFW B;  1XKA L;  2FLR L;  1KIG L;  1IQK L;  5L2Z L;  2P26 A;  2WPI E;  4JZE L;  5KIR A;  3TBD A;  3U7U G;  4XLW A;  2BOH A;  1DDX A;  5JBA E;  2XBX L;  4XL1 A;  4MMZ B;  2P93 L;  4NGA L;  3TZI A;  3PGH A;  1AUT L;  2WG3 C;  1CVU A;  4BDW A;  4LOR A;  1L5G B;  3P5B L;  1NFY B;  1TLE A;  2RHP A;  1NPE B;  3LN0 A;  5E8D A;  1LPK A;  2PR3 B;  1EAI C;  2BOK L;  2BQW A;  1WU1 B;  2KB9 A;  4OTY A;  2OYU P;  2W3K B;  3CA7 A;  1A3P A;  1DX5 I;  2G00 L;  2K2T A;  1W8B L;  4A7I A;  1P0S L;  1P9J A;  2WYJ B;  2FLB L;  5F19 A;  2PHB B;  1UZK A;  1UZQ A;  2XC0 L;  3KQB L;  1FF7 A;  4Z0K B;  2WPK E;  5IKV A;  4ISI L;  1C5M F;  5IKR A;  4D0F A;  5JBB E;  1HRF A;  2P3U A;  4TGF A;  1JBU L;  5JVY A;  2W2Q E;  4JZD L;  2EI8 B;  2WPM E;  3MQE A;  2AYL A;  5FDQ A;  2ADX A;  2Y5F L;  1LPZ A;  1IJQ A;  3EGF A;  1NT0 A;  2VH6 B;  1EPH A;  1FFM A;  4CUD A;  1DIY A;  1EPI A;  1QFK L;  2I9B A;  4Y7B B;  2K2S B;  2WFX B;  3KQE L;  3LC3 B;  4ZAE B;  5EGM B;  2OYE P;  1HAE A;  3SW2 A;  3KQD L;  3N8X A;  4XBM A;  4X8V L;  2WPL E;  4JYU L;  3KK6 A;  3QMO A;  3LN1 A;  3N8W A;  4Z0L A;  1CQE A;  3CEN L;  1KSN B;  5JVZ A;  2VWO L;  3GCX E;  1PGE A;  1B9W A;  1Q4G A;  4E1G A;  3H5C B;  1G1T A;  3N8Y A;  4ZXX L;  3FBY A;  1HT5 A;  1KLJ L;  1U8C B;  3LAQ A;  3HS5 A;  1UZJ A;  5CKQ A;  1F0S B;  1LMJ A;  3NJP C;  6COX A;  3KCG L;  1PRH A;  1YGC L;  1XFE A;  3SOB B;  1IOE L;  4D90 A;  4ZXY L;  1CCF A;  5CKM A;  5CIS A;  4MMY B;  4BXW A;  1FE2 A;  3HO5 A;  4Y7A B;  1WHE A;  2Q1J B;  1F7M A;  1G2M B;  5COX A;  1MQ5 L;  1W7X L;  5I46 L;  1L3Y A;  3N8W B;  5JB8 E;  1O5D L;  1EPJ A;  1FSB A;  1NFX B;  1YO8 A;  4YT7 L;  5JB9 E;  4FM5 A;  1G1S A;  1URK A;  2J38 B;  1HX2 A;  3HO3 A;  2Y7X B;  2BZ6 L;  2Y80 B;  1ATA A;  1YUK B;  4X8U L;  4BXS A;  3N8Y B;  1RFN B;  4BDX A;  2VWM K;  4JYV L;  2PUQ L;  1IQF L;  2YGP A;  1DVA L;  4PH9 A;  4M10 A;  1HAF A;  3Q3K B;  4M11 A;  2W2M E;  4AQT A;  2J95 B;  2TGF A;  3Q7D A;  3QH0 A;  2Y81 B;  2W2P E;  2W3I B;  5L30 L;  2UWP B;  3GIS X;  2W2N E;  1IGZ A;  1EBV A;  3K9X A;  2XBW L;  1XDT R;  2BQ6 A;  2WPJ E;  3TGF A;  1G1R A;  4YZU B;  1APQ A;  4Y76 B;  3NT1 A;  4Z6A L;  1LPG A;  1N1I A;  2VWL L;  3R05 A;  3NTB A;  2P16 L;  2J34 B;  3CS7 L;  3LIW B;  2P94 L;  1OB1 C;  4MMX B;  3GCW E;  2VH0 B;  3OLU A;  1WHF A;  1X7A L;  1UZP A;  2XBV L;  1LQD A;  1FJS L;  2EI7 B;  3TK6 B;  3TH3 L;  2Y5H L;  4X8S L;  2WPH E;  2WG4 B;  4RRY A;  3FCS B;  4RUT A;  1DQB A;  3RR3 A;  2KV4 A;  5F1A A;  1EMN A;  1IP0 A;  2BMG A;  1IGX A;  1TOZ A;  2UWL B;  2NPR A;  2FLG A;  3HO4 A;  4ZH8 B;  2XBY L;  2VVV L;  1IVO C;  3BPS E;  5JBC E;  4ZHA B;  1IQM L;  3LC5 B;  2W26 B;  1PFX L;  2WFT A;  2JKH L;  2BOX A;  3F1S B;  3KRK A;  1IQH L;  1I0U A;  2MGR A;  1COU A;  3V64 C;  3KQC L;  4C16 A;  3FFG L;  5K0H B;  1SZB A;  2UWO B;  2P95 L;  1EZQ B;  2W2O E;  1CVW L;  4X8T L;  1PTH A;  1ATD A;  1FAX L;  2FD6 A;  2P3T A;  3DEM A;  3M36 L;  3HS7 A;  1EQH A;  4YT6 L;  4RRW A;  2BOU A;  1IQE L;  2Y5G L;  5CKN A;  4BTT A;  1N7D A;  3SOQ A;  5KN5 C;  2F9B L;  3F6U L;  1IQJ L;  1K36 A;  2J2U B;  3ZYI B;  1EPG A;  1NFU B;  4CUF A;  1CCV A;  2M74 A;  2MGP A;  4G1M B;  3LTG D;  2D1J B;  2P3F N;  4Y79 B;  2MHP A;  1M1X B;  2BO2 A;  1K37 A;  2VVC K;  1KLI L;  1F7E A;  1J9C L;  1YUF A;  1IQG L;  1NZI A;  3NTG A;  1U67 A;  1TPG A;  1ATE A;  2CJI B;  4NG9 L;  2Y82 B;  3HS6 A;  4BTI A;  1HJ7 A;  1EMO A;  1Z6E L;  2XC5 L;  3BT2 A;  1V3X B;  3HPT A;  2Y38 A;  2RNL A;  4D0E A;  2B7D L;  2DDU A;  1MQ6 L;  1KLO A;  2VWN L;  1IQI L;  1NQL B;  3N8Z A;  4O02 B;  1IOX A;  1CEJ A;  2Y7Z B;  1F0R B;  2P28 B;  1JL9 A;  3POY A;  2KL7 A;  3ZYJ B;  3SOV A;  1MOX C;  1G1Q A;  4CSY A;  2VVU L;  3IJE B;  2J4I B;  1ATB A;  1FAK L;  3C9A C;  1JV2 B;  4CUE A;  2FZZ L;  2I9A A;  3ELA L;  5JW1 A;  2J94 B;  3CFW A;  3ENS A;  3BT1 A;  3U73 A;  4O1Z A;  1G2L B;  2P3F L;  1PXX A;  1IQL L;  2EI6 B;  3M37 L;  1Z6C A;  3QCW A;  4Y71 B;  2YGO A;  1ADX A;  3LTF B;  4NA9 L;  4JZF L;  4BTU A;  3V65 B;  1IQN L;  3TK5 B;  5L2Y L;  4Y6D B;  2XC4 L;  1HT8 A;  3MDL A;  3ASI A;  2H9E L;  2VJ3 A; 
#chains in the Genus database with same CATH topology
 3IIT B;  1CX2 A;  4OTJ A;  2GD4 A;  4LMF A;  1EGF A;  3KL6 B;  5IKQ A;  1GK5 A;  2RA0 L;  1HCG B;  2WYG B;  1ZAQ A;  1HRE A;  2BQ7 A;  1BF9 A;  3N8V A;  4RS0 A;  4ISH L;  1HZ8 A;  1YUG A;  1APO A;  1EQG A;  4COX A;  4RRX A;  2W86 A;  1XKB A;  4RRZ A;  5IKT A;  3ZYG A;  3OLT A;  1NFW B;  1XKA L;  2FLR L;  1KIG L;  1IQK L;  5L2Z L;  2P26 A;  2WPI E;  4JZE L;  5KIR A;  3TBD A;  3U7U G;  4XLW A;  2BOH A;  1DDX A;  5JBA E;  2XBX L;  4XL1 A;  4MMZ B;  2P93 L;  4NGA L;  3TZI A;  3PGH A;  1AUT L;  2WG3 C;  1CVU A;  4BDW A;  4LOR A;  1L5G B;  3P5B L;  1NFY B;  1TLE A;  2RHP A;  1NPE B;  3LN0 A;  5E8D A;  1LPK A;  2PR3 B;  1EAI C;  2BOK L;  2BQW A;  1WU1 B;  2KB9 A;  4OTY A;  2OYU P;  2W3K B;  3CA7 A;  1A3P A;  1DX5 I;  2G00 L;  2K2T A;  1W8B L;  4A7I A;  1P0S L;  1V1H A;  1P9J A;  2WYJ B;  2FLB L;  5F19 A;  1KKE A;  2PHB B;  1UZK A;  1UZQ A;  2XC0 L;  3KQB L;  1FF7 A;  4Z0K B;  2WPK E;  5IKV A;  2H9E C;  4ISI L;  1C5M F;  5IKR A;  4D0F A;  5JBB E;  2BT7 A;  1HRF A;  2P3U A;  4TGF A;  1JBU L;  5JVY A;  2W2Q E;  4JZD L;  2EI8 B;  2WPM E;  3MQE A;  2AYL A;  5FDQ A;  2ADX A;  2Y5F L;  1LPZ A;  1IJQ A;  3EGF A;  1NT0 A;  2VRS A;  2VH6 B;  1EPH A;  2YGQ A;  1FFM A;  4CUD A;  1DIY A;  1EPI A;  1QFK L;  2I9B A;  4Y7B B;  2K2S B;  2WFX B;  3KQE L;  3LC3 B;  4ZAE B;  5EGM B;  2OYE P;  1HAE A;  3SW2 A;  3KQD L;  3N8X A;  4XBM A;  4X8V L;  2WPL E;  4JYU L;  3KK6 A;  3QMO A;  3LN1 A;  3N8W A;  4Z0L A;  1CQE A;  2BSF A;  3CEN L;  1KSN B;  5JVZ A;  2VWO L;  3GCX E;  1PGE A;  4GU4 A;  1B9W A;  1Q4G A;  4E1G A;  3H5C B;  1G1T A;  3N8Y A;  4ZXX L;  3FBY A;  1HT5 A;  1KLJ L;  1U8C B;  3LAQ A;  3HS5 A;  1UZJ A;  5CKQ A;  1F0S B;  1LMJ A;  3NJP C;  6COX A;  3KCG L;  1PRH A;  1YGC L;  1XFE A;  3SOB B;  1IOE L;  4D90 A;  4ZXY L;  1CCF A;  5CKM A;  5CIS A;  4MMY B;  4BXW A;  1FE2 A;  3HO5 A;  4Y7A B;  1WHE A;  2Q1J B;  1F7M A;  1G2M B;  5COX A;  1MQ5 L;  1W7X L;  5I46 L;  1L3Y A;  3N8W B;  5JB8 E;  1O5D L;  1EPJ A;  1FSB A;  1NFX B;  1YO8 A;  4YT7 L;  5JB9 E;  4FM5 A;  1G1S A;  1URK A;  2J38 B;  1HX2 A;  3HO3 A;  2Y7X B;  2BZ6 L;  2Y80 B;  1ATA A;  1YUK B;  4X8U L;  4BXS A;  3N8Y B;  1RFN B;  4BDX A;  2VWM K;  4JYV L;  2PUQ L;  1IQF L;  2YGP A;  2WZP P;  1DVA L;  4PH9 A;  4M10 A;  1HAF A;  3Q3K B;  4M11 A;  2W2M E;  4AQT A;  2J95 B;  2TGF A;  3Q7D A;  3QH0 A;  2Y81 B;  2W2P E;  2W3I B;  5L30 L;  2UWP B;  3GIS X;  3S6X A;  2W2N E;  1IGZ A;  1EBV A;  3K9X A;  2XBW L;  1XDT R;  2BQ6 A;  2WPJ E;  3TGF A;  1G1R A;  4YZU B;  1APQ A;  4Y76 B;  3NT1 A;  4Z6A L;  1LPG A;  1N1I A;  2VWL L;  3R05 A;  3NTB A;  2P16 L;  2J34 B;  3CS7 L;  3LIW B;  2P94 L;  1OB1 C;  4MMX B;  3GCW E;  2VH0 B;  2JJL A;  3OLU A;  1WHF A;  1X7A L;  1UZP A;  2XBV L;  1LQD A;  1FJS L;  2EI7 B;  3TK6 B;  3TH3 L;  2Y5H L;  4X8S L;  2WPH E;  2WG4 B;  4RRY A;  3FCS B;  4RUT A;  1DQB A;  4GU3 A;  3RR3 A;  2KV4 A;  5F1A A;  1EMN A;  1IP0 A;  2BMG A;  1IGX A;  1TOZ A;  2UWL B;  2NPR A;  2FLG A;  3HO4 A;  4ZH8 B;  2HOR A;  2XBY L;  2VVV L;  1IVO C;  3BPS E;  5JBC E;  4ZHA B;  1IQM L;  3LC5 B;  2W26 B;  1PFX L;  2WFT A;  2JKH L;  2BOX A;  3F1S B;  3KRK A;  1IQH L;  1I0U A;  2MGR A;  1COU A;  1LK9 A;  3V64 C;  3KQC L;  1LMM A;  1QIU A;  4C16 A;  3FFG L;  5K0H B;  1SZB A;  2UWO B;  2P95 L;  1EZQ B;  2W2O E;  1CVW L;  4X8T L;  1PTH A;  1ATD A;  1FAX L;  2FD6 A;  2P3T A;  3DEM A;  3M36 L;  3HS7 A;  1EQH A;  4YT6 L;  4RRW A;  2BOU A;  1IQE L;  2Y5G L;  5CKN A;  4BTT A;  1N7D A;  3SOQ A;  5KN5 C;  2F9B L;  3F6U L;  1IQJ L;  1K36 A;  2J2U B;  3ZYI B;  1EPG A;  1NFU B;  4CUF A;  1CCV A;  2M74 A;  2MGP A;  4G1M B;  3LTG D;  2D1J B;  2P3F N;  4Y79 B;  2MHP A;  2BT8 A;  1M1X B;  2BO2 A;  1K37 A;  2VVC K;  1KLI L;  1F7E A;  1J9C L;  1YUF A;  1IQG L;  1NZI A;  3NTG A;  1U67 A;  1TPG A;  1ATE A;  2CJI B;  4NG9 L;  2Y82 B;  3HS6 A;  4A94 C;  4BTI A;  1HJ7 A;  2HOX A;  1EMO A;  1Z6E L;  2XC5 L;  3BT2 A;  1V3X B;  3HPT A;  2Y38 A;  2RNL A;  4D0E A;  2B7D L;  2DDU A;  1MQ6 L;  1KLO A;  2VWN L;  1IQI L;  1NQL B;  3N8Z A;  4O02 B;  1IOX A;  1CEJ A;  2Y7Z B;  1F0R B;  2P28 B;  1JL9 A;  3POY A;  2KL7 A;  3ZYJ B;  3SOV A;  1MOX C;  1G1Q A;  2KNI A;  4CSY A;  2VVU L;  3IJE B;  2J4I B;  1ATB A;  1FAK L;  3C9A C;  1JV2 B;  4CUE A;  2FZZ L;  2I9A A;  3ELA L;  5JW1 A;  2J94 B;  3CFW A;  3ENS A;  3BT1 A;  3U73 A;  4O1Z A;  1G2L B;  2P3F L;  1PXX A;  1IQL L;  2EI6 B;  3M37 L;  1Z6C A;  3QCW A;  4Y71 B;  2YGO A;  1ADX A;  1V1I A;  3LTF B;  4NA9 L;  4JZF L;  4BTU A;  3V65 B;  1IQN L;  3TK5 B;  5L2Y L;  4Y6D B;  2XC4 L;  1HT8 A;  3MDL A;  3ASI A;  2H9E L;  2VJ3 A; 
#chains in the Genus database with same CATH homology
 3IIT B;  1CX2 A;  4OTJ A;  2GD4 A;  4LMF A;  1EGF A;  3KL6 B;  5IKQ A;  1GK5 A;  2RA0 L;  1HCG B;  2WYG B;  1ZAQ A;  1HRE A;  2BQ7 A;  1BF9 A;  3N8V A;  4RS0 A;  4ISH L;  1HZ8 A;  1YUG A;  1APO A;  1EQG A;  4COX A;  4RRX A;  2W86 A;  1XKB A;  4RRZ A;  5IKT A;  3ZYG A;  3OLT A;  1NFW B;  1XKA L;  2FLR L;  1KIG L;  1IQK L;  5L2Z L;  2P26 A;  2WPI E;  4JZE L;  5KIR A;  3TBD A;  3U7U G;  4XLW A;  2BOH A;  1DDX A;  5JBA E;  2XBX L;  4XL1 A;  4MMZ B;  2P93 L;  4NGA L;  3TZI A;  3PGH A;  1AUT L;  2WG3 C;  1CVU A;  4BDW A;  4LOR A;  1L5G B;  3P5B L;  1NFY B;  1TLE A;  2RHP A;  1NPE B;  3LN0 A;  5E8D A;  1LPK A;  2PR3 B;  1EAI C;  2BOK L;  2BQW A;  1WU1 B;  2KB9 A;  4OTY A;  2OYU P;  2W3K B;  3CA7 A;  1A3P A;  1DX5 I;  2G00 L;  2K2T A;  1W8B L;  4A7I A;  1P0S L;  1P9J A;  2WYJ B;  2FLB L;  5F19 A;  2PHB B;  1UZK A;  1UZQ A;  2XC0 L;  3KQB L;  1FF7 A;  4Z0K B;  2WPK E;  5IKV A;  2H9E C;  4ISI L;  1C5M F;  5IKR A;  4D0F A;  5JBB E;  1HRF A;  2P3U A;  4TGF A;  1JBU L;  5JVY A;  2W2Q E;  4JZD L;  2EI8 B;  2WPM E;  3MQE A;  2AYL A;  5FDQ A;  2ADX A;  2Y5F L;  1LPZ A;  1IJQ A;  3EGF A;  1NT0 A;  2VH6 B;  1EPH A;  2YGQ A;  1FFM A;  4CUD A;  1DIY A;  1EPI A;  1QFK L;  2I9B A;  4Y7B B;  2K2S B;  2WFX B;  3KQE L;  3LC3 B;  4ZAE B;  5EGM B;  2OYE P;  1HAE A;  3SW2 A;  3KQD L;  3N8X A;  4XBM A;  4X8V L;  2WPL E;  4JYU L;  3KK6 A;  3QMO A;  3LN1 A;  3N8W A;  4Z0L A;  1CQE A;  3CEN L;  1KSN B;  5JVZ A;  2VWO L;  3GCX E;  1PGE A;  1B9W A;  1Q4G A;  4E1G A;  3H5C B;  1G1T A;  3N8Y A;  4ZXX L;  3FBY A;  1HT5 A;  1KLJ L;  1U8C B;  3LAQ A;  3HS5 A;  1UZJ A;  5CKQ A;  1F0S B;  1LMJ A;  3NJP C;  6COX A;  3KCG L;  1PRH A;  1YGC L;  1XFE A;  3SOB B;  1IOE L;  4D90 A;  4ZXY L;  1CCF A;  5CKM A;  5CIS A;  4MMY B;  4BXW A;  1FE2 A;  3HO5 A;  4Y7A B;  1WHE A;  2Q1J B;  1F7M A;  1G2M B;  5COX A;  1MQ5 L;  1W7X L;  5I46 L;  1L3Y A;  3N8W B;  5JB8 E;  1O5D L;  1EPJ A;  1FSB A;  1NFX B;  1YO8 A;  4YT7 L;  5JB9 E;  4FM5 A;  1G1S A;  1URK A;  2J38 B;  1HX2 A;  3HO3 A;  2Y7X B;  2BZ6 L;  2Y80 B;  1ATA A;  1YUK B;  4X8U L;  4BXS A;  3N8Y B;  1RFN B;  4BDX A;  2VWM K;  4JYV L;  2PUQ L;  1IQF L;  2YGP A;  2WZP P;  1DVA L;  4PH9 A;  4M10 A;  1HAF A;  3Q3K B;  4M11 A;  2W2M E;  4AQT A;  2J95 B;  2TGF A;  3Q7D A;  3QH0 A;  2Y81 B;  2W2P E;  2W3I B;  5L30 L;  2UWP B;  3GIS X;  3S6X A;  2W2N E;  1IGZ A;  1EBV A;  3K9X A;  2XBW L;  1XDT R;  2BQ6 A;  2WPJ E;  3TGF A;  1G1R A;  4YZU B;  1APQ A;  4Y76 B;  3NT1 A;  4Z6A L;  1LPG A;  1N1I A;  2VWL L;  3R05 A;  3NTB A;  2P16 L;  2J34 B;  3CS7 L;  3LIW B;  2P94 L;  1OB1 C;  4MMX B;  3GCW E;  2VH0 B;  3OLU A;  1WHF A;  1X7A L;  1UZP A;  2XBV L;  1LQD A;  1FJS L;  2EI7 B;  3TK6 B;  3TH3 L;  2Y5H L;  4X8S L;  2WPH E;  2WG4 B;  4RRY A;  3FCS B;  4RUT A;  1DQB A;  3RR3 A;  2KV4 A;  5F1A A;  1EMN A;  1IP0 A;  2BMG A;  1IGX A;  1TOZ A;  2UWL B;  2NPR A;  2FLG A;  3HO4 A;  4ZH8 B;  2XBY L;  2VVV L;  1IVO C;  3BPS E;  5JBC E;  4ZHA B;  1IQM L;  3LC5 B;  2W26 B;  1PFX L;  2WFT A;  2JKH L;  2BOX A;  3F1S B;  3KRK A;  1IQH L;  1I0U A;  2MGR A;  1COU A;  3V64 C;  3KQC L;  1LMM A;  4C16 A;  3FFG L;  5K0H B;  1SZB A;  2UWO B;  2P95 L;  1EZQ B;  2W2O E;  1CVW L;  4X8T L;  1PTH A;  1ATD A;  1FAX L;  2FD6 A;  2P3T A;  3DEM A;  3M36 L;  3HS7 A;  1EQH A;  4YT6 L;  4RRW A;  2BOU A;  1IQE L;  2Y5G L;  5CKN A;  4BTT A;  1N7D A;  3SOQ A;  5KN5 C;  2F9B L;  3F6U L;  1IQJ L;  1K36 A;  2J2U B;  3ZYI B;  1EPG A;  1NFU B;  4CUF A;  1CCV A;  2M74 A;  2MGP A;  4G1M B;  3LTG D;  2D1J B;  2P3F N;  4Y79 B;  2MHP A;  1M1X B;  2BO2 A;  1K37 A;  2VVC K;  1KLI L;  1F7E A;  1J9C L;  1YUF A;  1IQG L;  1NZI A;  3NTG A;  1U67 A;  1TPG A;  1ATE A;  2CJI B;  4NG9 L;  2Y82 B;  3HS6 A;  4A94 C;  4BTI A;  1HJ7 A;  1EMO A;  1Z6E L;  2XC5 L;  3BT2 A;  1V3X B;  3HPT A;  2Y38 A;  2RNL A;  4D0E A;  2B7D L;  2DDU A;  1MQ6 L;  1KLO A;  2VWN L;  1IQI L;  1NQL B;  3N8Z A;  4O02 B;  1IOX A;  1CEJ A;  2Y7Z B;  1F0R B;  2P28 B;  1JL9 A;  3POY A;  2KL7 A;  3ZYJ B;  3SOV A;  1MOX C;  1G1Q A;  2KNI A;  4CSY A;  2VVU L;  3IJE B;  2J4I B;  1ATB A;  1FAK L;  3C9A C;  1JV2 B;  4CUE A;  2FZZ L;  2I9A A;  3ELA L;  5JW1 A;  2J94 B;  3CFW A;  3ENS A;  3BT1 A;  3U73 A;  4O1Z A;  1G2L B;  2P3F L;  1PXX A;  1IQL L;  2EI6 B;  3M37 L;  1Z6C A;  3QCW A;  4Y71 B;  2YGO A;  1ADX A;  3LTF B;  4NA9 L;  4JZF L;  4BTU A;  3V65 B;  1IQN L;  3TK5 B;  5L2Y L;  4Y6D B;  2XC4 L;  1HT8 A;  3MDL A;  3ASI A;  2H9E L;  2VJ3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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