5L30L

Factor viia in complex with the inhibitor (2r,15r)-2-[(1-aminoisoquinolin-6-yl)amino]-4,15,17-trimethyl-7-[1-(1h-tetrazol-5-yl)cyclopropyl]-13-oxa-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaene-3,12-dione
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
56
structure length
56
Chain Sequence
LICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Synthesis and P1' SAR exploration of potent macrocyclic tissue factor-factor VIIa inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Coagulation factor VII (Heavy Chain)
total genus 13
structure length 56
sequence length 56
ec nomenclature ec 3.4.21.21: Coagulation factor VIIa.
pdb deposition date 2016-08-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 5l30L00
4NG9L 2WG4B 4Z0KB 3C9AC 1COUA 3QH0A 4D0FA 2EI6B 5IKRA 3N8ZA 2W3IB 1EPHA 2D1JB 5FDQA 5K0HB 2BOUA 5JVYA 2VWLL 3LTGD 2H9EL 3RR3A 1TOZA 4Z6AL 3ENSA 2MHPA 2RA0L 1N7DA 2P26A 2BMGA 1JBUL 3FBYA 2Y7ZB 1G1QA 4JYUL 4CUEA 3NTGA 2VJ3A 1YUKB 2P3FN 2FD6A 3NT1A 1IQFL 3NTBA 1FAXL 4BXWA 1KIGL 2W3KB 3LAQA 4RS0A 1EMOA 1L3YA 4NGAL 2J2UB 5L2ZL 2J38B 1LPKA 1WU1B 4FM5A 4BDWA 1XDTR 2OYEP 1CQEA 1MQ6L 1G1SA 1ATEA 1LMJA 4BDXA 3Q7DA 1M1XB 2BQ7A 1MQ5L 1FF7A 4X8VL 2Y7XB 3OLTA 1F7EA 1HAFA 2BOHA 1FFMA 3BPSE 2PUQL 1DX5I 6COXA 1K37A 4PH9A 1NFYB 3TGFA 1URKA 4LORA 3LC3B 1V3XB 3FCSB 1YGCL 4BTUA 3F1SB 4MMZB 1WHEA 2W86A 1IQLL 2YGPA 1EMNA 3FFGL 2XBXL 2VVCK 1SZBA 2WFXB 1UZJA 4CSYA 4M11A 1LPZA 1EZQB 4G1MB 2GD4A 2FLGA 4JZDL 4X8UL 2JKHL 2W2OE 4XL1A 3EGFA 1KLJL 4OTJA 2WPHE 2XBWL 2XBYL 1DIYA 5CKNA 3Q3KB 5IKTA 3U7UG 2Y5FL 2WYJB 1FJSL 3HS5A 2Y5GL 2WPJE 1XKBA 1IGXA 3V64C 1A3PA 2CJIB 3CENL 2UWPB 5JBCE 4Y79B 1NPEB 1ATAA 1JL9A 1IQNL 1HAEA 3MQEA 4CUFA 2W2PE 2BZ6L 1AUTL 3CFWA 1ADXA 1XFEA 1X7AL 5EGMB 5CKQA 5JBBE 3KQEL 1IOEL 4M10A 4XLWA 3KL6B 4D0EA 4Z0LA 1IQJL 2W26B 1G2MB 1J9CL 2K2TA 3ZYGA 4C16A 2OYUP 1CEJA 4CUDA 1EGFA 3POYA 1FE2A 2DDUA 1EBVA 1B9WA 4MMYB 3SOBB 3KCGL 1CCFA 2M74A 1YUGA 3OLUA 3CA7A 2W2NE 1NFUB 4JZEL 1HX2A 3HO4A 2RNLA 2B7DL 2FLBL 2J34B 2J94B 4OTYA 1L5GB 2MGRA 2BOKL 5JW1A 1EQHA 1W8BL 1Z6EL 3GCWE 4BTTA 5IKVA 4ISIL 2J4IB 1DQBA 3GCXE 3MDLA 2ADXA 2Y5HL 3LN0A 4ISHL 2AYLA 1IQEL 4RUTA 1EAIC 1UZPA 5E8DA 1EPGA 3KQDL 2P28B 1EQGA 2VWNL 2XC4L 5KIRA 3LTFB 4BTIA 4RRWA 3R05A 3QCWA 5JB8E 1C5MF 3KRKA 1IQGL 1RFNB 1P0SL 3LC5B 3N8XA 3ZYJB 3QMOA 1NFWB 2WYGB 5JVZA 5KN5C 3N8VA 1IVOC 1KLIL 2F9BL 1NQLB 4RRYA 1YUFA 1IJQA 1PXXA 1G1TA 1W7XL 1U8CB 2P3TA 2P94L 1FAKL 3HS6A 2BOXA 5F1AA 2WPLE 1UZKA 1QFKL 1NFXB 4YT6L 4ZAEB 4ZXYL 2RHPA 4COXA 1ATDA 4RRZA 3SOVA 3DEMA 2W2QE 2VVUL 2KL7A 1HRFA 3ZYIB 5IKQA 3SOQA 4YZUB 4ZXXL 4RRXA 3U73A 2PR3B 2WPME 1PGEA 2P93L 3M36L 1APOA 5JB9E 2WG3C 4O1ZA 4X8TL 2K2SB 1IQML 3PGHA 1K36A 2I9AA 2G00L 1G2LB 4Y7AB 4AQTA 3ASIA 1NT0A 2FZZL 1EPJA 1HJ7A 1F7MA 1IQIL 2Y38A 4O02B 1PFXL 1DVAL 2XBVL 1Q4GA 2Q1JB 3KK6A 2W2ME 4MMXB 2P3FL 3TBDA 3ELAL 2PHBB 4JYVL 1LQDA 1ATBA 4NA9L 1CCVA 3IJEB 1DDXA 2TGFA 3HO3A 3LN1A 5CKMA 2FLRL 2NPRA 2VH0B 1JV2B 2Y80B 2BQWA 1XKAL 1G1RA 5L30L 2MGPA 4Y71B 1KLOA 3TZIA 2P16L 2I9BA 1HT8A 4X8SL 2BO2A 1TLEA 3K9XA 4Y6DB 3H5CB 1O5DL 4E1GA 2EI7B 4XBMA 3N8WB 3IITB 1TPGA 1IGZA 1ZAQA 3P5BL 4Y76B 3HS7A 3TK6B 2VVVL 1CVUA 3N8YB 1GK5A 1EPIA 3F6UL 2UWLB 2VH6B 1Z6CA 3LIWB 1IOXA 4YT7L 1IQKL 3GISX 1I0UA 1KSNB 1YO8A 3NJPC 1BF9A 1P9JA 3TH3L 4LMFA 2EI8B 1CX2A 5L2YL 1UZQA 2J95B 1HREA 5COXA 2Y81B 3SW2A 2YGOA 2Y82B 2KB9A 4ZH8B 1MOXC 1IQHL 4TGFA 5I46L 2WPIE 4D90A 2WFTA 1F0SB 4Y7BB 2BQ6A 1HZ8A 3N8WA 1PTHA 2KV4A 3BT1A 3BT2A 5JBAE 4BXSA 1NZIA 3M37L 3KQBL 1APQA 2VWMK 1U67A 1IP0A 4JZFL 5F19A 3TK5B 1PRHA 3HPTA 3N8YA 1F0RB 2P3UA 2XC0L 2VWOL 2XC5L 1WHFA 4A7IA 1FSBA 3CS7L 3KQCL 3V65B 2UWOB 1HT5A 1HCGB 3HO5A 1N1IA 1OB1C 1LPGA 2P95L 5CISA 4ZHAB 2WPKE 1CVWL
chains in the Genus database with same CATH superfamily
2H9EC 4NG9L 2WG4B 4Z0KB 3C9AC 1COUA 3QH0A 4D0FA 2EI6B 5IKRA 3N8ZA 2W3IB 1EPHA 2D1JB 5FDQA 5K0HB 2BOUA 5JVYA 2VWLL 3LTGD 2H9EL 3RR3A 1TOZA 2VRSA 4Z6AL 3ENSA 2MHPA 2RA0L 1N7DA 2P26A 2BMGA 1JBUL 3FBYA 2Y7ZB 1G1QA 4JYUL 4CUEA 3NTGA 2VJ3A 1YUKB 2P3FN 2FD6A 3NT1A 4A94C 1IQFL 3NTBA 1FAXL 4BXWA 1KIGL 2W3KB 3LAQA 4RS0A 1EMOA 1L3YA 4NGAL 2J2UB 5L2ZL 2J38B 1LPKA 1WU1B 4FM5A 4BDWA 1XDTR 2OYEP 1CQEA 1MQ6L 1G1SA 1ATEA 1LMJA 2HORA 4BDXA 3Q7DA 1M1XB 2BQ7A 1MQ5L 1FF7A 4X8VL 2Y7XB 3OLTA 1F7EA 1HAFA 2BOHA 1FFMA 3BPSE 2PUQL 1DX5I 6COXA 1K37A 4PH9A 1NFYB 3TGFA 1URKA 4LORA 3LC3B 1V3XB 3FCSB 1YGCL 4BTUA 3F1SB 4MMZB 1WHEA 2W86A 1IQLL 2YGPA 1EMNA 3FFGL 2XBXL 2VVCK 1SZBA 2WFXB 1UZJA 4CSYA 4M11A 1LPZA 1EZQB 4G1MB 2GD4A 2KNIA 2FLGA 4JZDL 4X8UL 2JKHL 2W2OE 4XL1A 3EGFA 1KLJL 4OTJA 2WPHE 2XBWL 2XBYL 1DIYA 5CKNA 3Q3KB 5IKTA 3U7UG 2Y5FL 2WYJB 1FJSL 3HS5A 2Y5GL 2WPJE 1XKBA 1IGXA 3V64C 1A3PA 2CJIB 3CENL 2UWPB 5JBCE 4Y79B 1NPEB 1ATAA 1JL9A 3S6XA 1IQNL 1HAEA 3MQEA 4CUFA 2W2PE 1LK9A 2BZ6L 1AUTL 3CFWA 1ADXA 1XFEA 1X7AL 5EGMB 5CKQA 5JBBE 3KQEL 4GU4A 1IOEL 4M10A 4XLWA 3KL6B 4D0EA 4Z0LA 1IQJL 2WZPP 2W26B 1G2MB 1J9CL 2K2TA 3ZYGA 4C16A 2OYUP 1CEJA 4CUDA 1EGFA 3POYA 1FE2A 2DDUA 1EBVA 1B9WA 2YGQA 4MMYB 3SOBB 3KCGL 1CCFA 2M74A 1YUGA 3OLUA 3CA7A 2W2NE 1NFUB 2BT8A 4JZEL 1HX2A 3HO4A 2RNLA 2B7DL 2FLBL 2J34B 2J94B 4OTYA 1L5GB 2MGRA 2BOKL 5JW1A 1EQHA 1W8BL 1Z6EL 3GCWE 4BTTA 5IKVA 4ISIL 2J4IB 1DQBA 3GCXE 3MDLA 2ADXA 2Y5HL 3LN0A 4ISHL 2AYLA 1IQEL 4RUTA 1EAIC 1UZPA 5E8DA 1EPGA 1QIUA 3KQDL 2P28B 1EQGA 1V1HA 2VWNL 2XC4L 5KIRA 3LTFB 4BTIA 4RRWA 3R05A 3QCWA 5JB8E 1C5MF 3KRKA 1IQGL 1RFNB 1P0SL 3LC5B 3N8XA 3ZYJB 3QMOA 1NFWB 2WYGB 5JVZA 5KN5C 3N8VA 1IVOC 1KLIL 2F9BL 1NQLB 4RRYA 1YUFA 1IJQA 1PXXA 1G1TA 1W7XL 1U8CB 2P3TA 2P94L 1FAKL 3HS6A 2BOXA 5F1AA 2WPLE 1UZKA 1QFKL 1NFXB 4YT6L 4ZAEB 4ZXYL 2RHPA 4COXA 1ATDA 4RRZA 3SOVA 3DEMA 2W2QE 2VVUL 2KL7A 1HRFA 3ZYIB 5IKQA 3SOQA 4YZUB 4ZXXL 4RRXA 3U73A 2PR3B 2WPME 1PGEA 2P93L 2HOXA 3M36L 1APOA 5JB9E 2WG3C 4O1ZA 4X8TL 2K2SB 1IQML 3PGHA 1K36A 2I9AA 2G00L 1G2LB 4Y7AB 4AQTA 3ASIA 1NT0A 2FZZL 1EPJA 1HJ7A 1F7MA 1IQIL 2Y38A 4O02B 1PFXL 1DVAL 1KKEA 2XBVL 1Q4GA 2Q1JB 3KK6A 2W2ME 4MMXB 2P3FL 3TBDA 3ELAL 2PHBB 4JYVL 1LQDA 1ATBA 4NA9L 1CCVA 3IJEB 1DDXA 2TGFA 3HO3A 3LN1A 5CKMA 2FLRL 2NPRA 2VH0B 1JV2B 2Y80B 2BQWA 1XKAL 4GU3A 1G1RA 5L30L 2MGPA 4Y71B 1KLOA 3TZIA 2P16L 2I9BA 1HT8A 4X8SL 2BO2A 1TLEA 3K9XA 4Y6DB 3H5CB 1O5DL 4E1GA 2EI7B 4XBMA 3N8WB 3IITB 1TPGA 1IGZA 1ZAQA 3P5BL 4Y76B 3HS7A 3TK6B 2VVVL 2JJLA 1CVUA 3N8YB 1GK5A 1EPIA 3F6UL 2UWLB 2VH6B 1Z6CA 3LIWB 1IOXA 4YT7L 1IQKL 3GISX 1I0UA 1KSNB 1YO8A 3NJPC 1BF9A 1P9JA 3TH3L 4LMFA 2EI8B 1CX2A 5L2YL 1UZQA 2J95B 1HREA 5COXA 2Y81B 3SW2A 2YGOA 2Y82B 2KB9A 4ZH8B 1MOXC 1IQHL 4TGFA 5I46L 2WPIE 4D90A 2WFTA 1F0SB 4Y7BB 2BSFA 2BQ6A 1HZ8A 3N8WA 1PTHA 2KV4A 3BT1A 3BT2A 5JBAE 4BXSA 1NZIA 3M37L 3KQBL 1APQA 2VWMK 1U67A 1IP0A 4JZFL 1V1IA 5F19A 3TK5B 1PRHA 3HPTA 3N8YA 1LMMA 2XC0L 1F0RB 2P3UA 2VWOL 2XC5L 1WHFA 4A7IA 1FSBA 2BT7A 3CS7L 3KQCL 3V65B 2UWOB 1HT5A 1HCGB 3HO5A 1N1IA 1OB1C 1LPGA 2P95L 5CISA 4ZHAB 2WPKE 1CVWL
chains in the Genus database with same CATH topology
2H9EC 4NG9L 2WG4B 4Z0KB 3C9AC 1COUA 3QH0A 4D0FA 2EI6B 5IKRA 3N8ZA 2W3IB 1EPHA 2D1JB 5FDQA 5K0HB 2BOUA 5JVYA 2VWLL 3LTGD 2H9EL 3RR3A 1TOZA 4Z6AL 3ENSA 2MHPA 2RA0L 1N7DA 2P26A 2BMGA 1JBUL 3FBYA 2Y7ZB 1G1QA 4JYUL 4CUEA 3NTGA 2VJ3A 1YUKB 2P3FN 2FD6A 3NT1A 4A94C 1IQFL 3NTBA 1FAXL 4BXWA 1KIGL 2W3KB 3LAQA 4RS0A 1EMOA 1L3YA 4NGAL 2J2UB 5L2ZL 2J38B 1LPKA 1WU1B 4FM5A 4BDWA 1XDTR 2OYEP 1CQEA 1MQ6L 1G1SA 1ATEA 1LMJA 4BDXA 3Q7DA 1M1XB 2BQ7A 1MQ5L 1FF7A 4X8VL 2Y7XB 3OLTA 1F7EA 1HAFA 2BOHA 1FFMA 3BPSE 2PUQL 1DX5I 6COXA 1K37A 4PH9A 1NFYB 3TGFA 1URKA 4LORA 3LC3B 1V3XB 3FCSB 1YGCL 4BTUA 3F1SB 4MMZB 1WHEA 2W86A 1IQLL 2YGPA 1EMNA 3FFGL 2XBXL 2VVCK 1SZBA 2WFXB 1UZJA 4CSYA 4M11A 1LPZA 1EZQB 4G1MB 2GD4A 2KNIA 2FLGA 4JZDL 4X8UL 2JKHL 2W2OE 4XL1A 3EGFA 1KLJL 4OTJA 2WPHE 2XBWL 2XBYL 1DIYA 5CKNA 3Q3KB 5IKTA 3U7UG 2Y5FL 2WYJB 1FJSL 3HS5A 2Y5GL 2WPJE 1XKBA 1IGXA 3V64C 1A3PA 2CJIB 3CENL 2UWPB 5JBCE 4Y79B 1NPEB 1ATAA 1JL9A 3S6XA 1IQNL 1HAEA 3MQEA 4CUFA 2W2PE 2BZ6L 1AUTL 3CFWA 1ADXA 1XFEA 1X7AL 5EGMB 5CKQA 5JBBE 3KQEL 1IOEL 4M10A 4XLWA 3KL6B 4D0EA 4Z0LA 1IQJL 2WZPP 2W26B 1G2MB 1J9CL 2K2TA 3ZYGA 4C16A 2OYUP 1CEJA 4CUDA 1EGFA 3POYA 1FE2A 2DDUA 1EBVA 1B9WA 2YGQA 4MMYB 3SOBB 3KCGL 1CCFA 2M74A 1YUGA 3OLUA 3CA7A 2W2NE 1NFUB 4JZEL 1HX2A 3HO4A 2RNLA 2B7DL 2FLBL 2J34B 2J94B 4OTYA 1L5GB 2MGRA 2BOKL 5JW1A 1EQHA 1W8BL 1Z6EL 3GCWE 4BTTA 5IKVA 4ISIL 2J4IB 1DQBA 3GCXE 3MDLA 3LN0A 2ADXA 2Y5HL 4ISHL 2AYLA 1IQEL 4RUTA 1EAIC 1UZPA 5E8DA 1EPGA 3KQDL 2P28B 1EQGA 2VWNL 2XC4L 5KIRA 3LTFB 4BTIA 4RRWA 3R05A 3QCWA 5JB8E 1C5MF 3KRKA 1IQGL 1RFNB 1P0SL 3LC5B 3N8XA 3ZYJB 3QMOA 1NFWB 2WYGB 5JVZA 5KN5C 3N8VA 1IVOC 1KLIL 2F9BL 1NQLB 4RRYA 1YUFA 1IJQA 1PXXA 1G1TA 1W7XL 1U8CB 2P3TA 2P94L 1FAKL 3HS6A 2BOXA 5F1AA 2WPLE 1UZKA 1QFKL 1NFXB 4YT6L 4ZAEB 4ZXYL 2RHPA 4COXA 1ATDA 4RRZA 3SOVA 3DEMA 2W2QE 2VVUL 2KL7A 1HRFA 3ZYIB 5IKQA 3SOQA 4YZUB 4ZXXL 4RRXA 3U73A 2PR3B 2WPME 1PGEA 2P93L 3M36L 1APOA 5JB9E 2WG3C 4O1ZA 4X8TL 2K2SB 1IQML 3PGHA 1K36A 2I9AA 2G00L 1G2LB 4Y7AB 4AQTA 3ASIA 1NT0A 2FZZL 1EPJA 1HJ7A 1F7MA 1IQIL 2Y38A 4O02B 1PFXL 1DVAL 2XBVL 1Q4GA 2Q1JB 3KK6A 2W2ME 4MMXB 2P3FL 3TBDA 3ELAL 2PHBB 4JYVL 1LQDA 1ATBA 4NA9L 1CCVA 3IJEB 1DDXA 2TGFA 3HO3A 3LN1A 5CKMA 2FLRL 2NPRA 2VH0B 1JV2B 2Y80B 2BQWA 1XKAL 1G1RA 5L30L 2MGPA 4Y71B 1KLOA 3TZIA 2P16L 2I9BA 1HT8A 4X8SL 2BO2A 1TLEA 3K9XA 4Y6DB 3H5CB 1O5DL 4E1GA 2EI7B 4XBMA 3N8WB 3IITB 1TPGA 1IGZA 1ZAQA 3P5BL 4Y76B 3HS7A 3TK6B 2VVVL 1CVUA 3N8YB 1GK5A 1EPIA 3F6UL 2UWLB 2VH6B 1Z6CA 3LIWB 1IOXA 4YT7L 1IQKL 3GISX 1I0UA 1KSNB 1YO8A 3NJPC 1BF9A 1P9JA 3TH3L 4LMFA 2EI8B 1CX2A 5L2YL 1UZQA 2J95B 1HREA 5COXA 2Y81B 3SW2A 2YGOA 2Y82B 2KB9A 4ZH8B 1MOXC 1IQHL 4TGFA 5I46L 2WPIE 4D90A 2WFTA 1F0SB 4Y7BB 2BQ6A 1HZ8A 3N8WA 1PTHA 2KV4A 3BT1A 3BT2A 5JBAE 4BXSA 1NZIA 3M37L 3KQBL 1APQA 2VWMK 1U67A 1IP0A 4JZFL 5F19A 3TK5B 1PRHA 3HPTA 3N8YA 1LMMA 1F0RB 2P3UA 2XC0L 2VWOL 2XC5L 1WHFA 4A7IA 1FSBA 3CS7L 3KQCL 3V65B 2UWOB 1HT5A 1HCGB 3HO5A 1N1IA 1OB1C 1LPGA 2P95L 5CISA 4ZHAB 2WPKE 1CVWL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NG9 L;  2WG4 B;  4Z0K B;  3C9A C;  1COU A;  3QH0 A;  4D0F A;  2EI6 B;  5IKR A;  3N8Z A;  2W3I B;  1EPH A;  2D1J B;  5FDQ A;  5K0H B;  2BOU A;  5JVY A;  2VWL L;  3LTG D;  2H9E L;  3RR3 A;  1TOZ A;  4Z6A L;  3ENS A;  2MHP A;  2RA0 L;  1N7D A;  2P26 A;  2BMG A;  1JBU L;  3FBY A;  2Y7Z B;  1G1Q A;  4JYU L;  4CUE A;  3NTG A;  2VJ3 A;  1YUK B;  2P3F N;  2FD6 A;  3NT1 A;  1IQF L;  3NTB A;  1FAX L;  4BXW A;  1KIG L;  2W3K B;  3LAQ A;  4RS0 A;  1EMO A;  1L3Y A;  4NGA L;  2J2U B;  5L2Z L;  2J38 B;  1LPK A;  1WU1 B;  4FM5 A;  4BDW A;  1XDT R;  2OYE P;  1CQE A;  1MQ6 L;  1G1S A;  1ATE A;  1LMJ A;  4BDX A;  3Q7D A;  1M1X B;  2BQ7 A;  1MQ5 L;  1FF7 A;  4X8V L;  2Y7X B;  3OLT A;  1F7E A;  1HAF A;  2BOH A;  1FFM A;  3BPS E;  2PUQ L;  1DX5 I;  6COX A;  1K37 A;  4PH9 A;  1NFY B;  3TGF A;  1URK A;  4LOR A;  3LC3 B;  1V3X B;  3FCS B;  1YGC L;  4BTU A;  3F1S B;  4MMZ B;  1WHE A;  2W86 A;  1IQL L;  2YGP A;  1EMN A;  3FFG L;  2XBX L;  2VVC K;  1SZB A;  2WFX B;  1UZJ A;  4CSY A;  4M11 A;  1LPZ A;  1EZQ B;  4G1M B;  2GD4 A;  2FLG A;  4JZD L;  4X8U L;  2JKH L;  2W2O E;  4XL1 A;  3EGF A;  1KLJ L;  4OTJ A;  2WPH E;  2XBW L;  2XBY L;  1DIY A;  5CKN A;  3Q3K B;  5IKT A;  3U7U G;  2Y5F L;  2WYJ B;  1FJS L;  3HS5 A;  2Y5G L;  2WPJ E;  1XKB A;  1IGX A;  3V64 C;  1A3P A;  2CJI B;  3CEN L;  2UWP B;  5JBC E;  4Y79 B;  1NPE B;  1ATA A;  1JL9 A;  1IQN L;  1HAE A;  3MQE A;  4CUF A;  2W2P E;  2BZ6 L;  1AUT L;  3CFW A;  1ADX A;  1XFE A;  1X7A L;  5EGM B;  5CKQ A;  5JBB E;  3KQE L;  1IOE L;  4M10 A;  4XLW A;  3KL6 B;  4D0E A;  4Z0L A;  1IQJ L;  2W26 B;  1G2M B;  1J9C L;  2K2T A;  3ZYG A;  4C16 A;  2OYU P;  1CEJ A;  4CUD A;  1EGF A;  3POY A;  1FE2 A;  2DDU A;  1EBV A;  1B9W A;  4MMY B;  3SOB B;  3KCG L;  1CCF A;  2M74 A;  1YUG A;  3OLU A;  3CA7 A;  2W2N E;  1NFU B;  4JZE L;  1HX2 A;  3HO4 A;  2RNL A;  2B7D L;  2FLB L;  2J34 B;  2J94 B;  4OTY A;  1L5G B;  2MGR A;  2BOK L;  5JW1 A;  1EQH A;  1W8B L;  1Z6E L;  3GCW E;  4BTT A;  5IKV A;  4ISI L;  2J4I B;  1DQB A;  3GCX E;  3MDL A;  2ADX A;  2Y5H L;  3LN0 A;  4ISH L;  2AYL A;  1IQE L;  4RUT A;  1EAI C;  1UZP A;  5E8D A;  1EPG A;  3KQD L;  2P28 B;  1EQG A;  2VWN L;  2XC4 L;  5KIR A;  3LTF B;  4BTI A;  4RRW A;  3R05 A;  3QCW A;  5JB8 E;  1C5M F;  3KRK A;  1IQG L;  1RFN B;  1P0S L;  3LC5 B;  3N8X A;  3ZYJ B;  3QMO A;  1NFW B;  2WYG B;  5JVZ A;  5KN5 C;  3N8V A;  1IVO C;  1KLI L;  2F9B L;  1NQL B;  4RRY A;  1YUF A;  1IJQ A;  1PXX A;  1G1T A;  1W7X L;  1U8C B;  2P3T A;  2P94 L;  1FAK L;  3HS6 A;  2BOX A;  5F1A A;  2WPL E;  1UZK A;  1QFK L;  1NFX B;  4YT6 L;  4ZAE B;  4ZXY L;  2RHP A;  4COX A;  1ATD A;  4RRZ A;  3SOV A;  3DEM A;  2W2Q E;  2VVU L;  2KL7 A;  1HRF A;  3ZYI B;  5IKQ A;  3SOQ A;  4YZU B;  4ZXX L;  4RRX A;  3U73 A;  2PR3 B;  2WPM E;  1PGE A;  2P93 L;  3M36 L;  1APO A;  5JB9 E;  2WG3 C;  4O1Z A;  4X8T L;  2K2S B;  1IQM L;  3PGH A;  1K36 A;  2I9A A;  2G00 L;  1G2L B;  4Y7A B;  4AQT A;  3ASI A;  1NT0 A;  2FZZ L;  1EPJ A;  1HJ7 A;  1F7M A;  1IQI L;  2Y38 A;  4O02 B;  1PFX L;  1DVA L;  2XBV L;  1Q4G A;  2Q1J B;  3KK6 A;  2W2M E;  4MMX B;  2P3F L;  3TBD A;  3ELA L;  2PHB B;  4JYV L;  1LQD A;  1ATB A;  4NA9 L;  1CCV A;  3IJE B;  1DDX A;  2TGF A;  3HO3 A;  3LN1 A;  5CKM A;  2FLR L;  2NPR A;  2VH0 B;  1JV2 B;  2Y80 B;  2BQW A;  1XKA L;  1G1R A;  5L30 L;  2MGP A;  4Y71 B;  1KLO A;  3TZI A;  2P16 L;  2I9B A;  1HT8 A;  4X8S L;  2BO2 A;  1TLE A;  3K9X A;  4Y6D B;  3H5C B;  1O5D L;  4E1G A;  2EI7 B;  4XBM A;  3N8W B;  3IIT B;  1TPG A;  1IGZ A;  1ZAQ A;  3P5B L;  4Y76 B;  3HS7 A;  3TK6 B;  2VVV L;  1CVU A;  3N8Y B;  1GK5 A;  1EPI A;  3F6U L;  2UWL B;  2VH6 B;  1Z6C A;  3LIW B;  1IOX A;  4YT7 L;  1IQK L;  3GIS X;  1I0U A;  1KSN B;  1YO8 A;  3NJP C;  1BF9 A;  1P9J A;  3TH3 L;  4LMF A;  2EI8 B;  1CX2 A;  5L2Y L;  1UZQ A;  2J95 B;  1HRE A;  5COX A;  2Y81 B;  3SW2 A;  2YGO A;  2Y82 B;  2KB9 A;  4ZH8 B;  1MOX C;  1IQH L;  4TGF A;  5I46 L;  2WPI E;  4D90 A;  2WFT A;  1F0S B;  4Y7B B;  2BQ6 A;  1HZ8 A;  3N8W A;  1PTH A;  2KV4 A;  3BT1 A;  3BT2 A;  5JBA E;  4BXS A;  1NZI A;  3M37 L;  3KQB L;  1APQ A;  2VWM K;  1U67 A;  1IP0 A;  4JZF L;  5F19 A;  3TK5 B;  1PRH A;  3HPT A;  3N8Y A;  1F0R B;  2P3U A;  2XC0 L;  2VWO L;  2XC5 L;  1WHF A;  4A7I A;  1FSB A;  3CS7 L;  3KQC L;  3V65 B;  2UWO B;  1HT5 A;  1HCG B;  3HO5 A;  1N1I A;  1OB1 C;  1LPG A;  2P95 L;  5CIS A;  4ZHA B;  2WPK E;  1CVW L; 
#chains in the Genus database with same CATH topology
 2H9E C;  4NG9 L;  2WG4 B;  4Z0K B;  3C9A C;  1COU A;  3QH0 A;  4D0F A;  2EI6 B;  5IKR A;  3N8Z A;  2W3I B;  1EPH A;  2D1J B;  5FDQ A;  5K0H B;  2BOU A;  5JVY A;  2VWL L;  3LTG D;  2H9E L;  3RR3 A;  1TOZ A;  2VRS A;  4Z6A L;  3ENS A;  2MHP A;  2RA0 L;  1N7D A;  2P26 A;  2BMG A;  1JBU L;  3FBY A;  2Y7Z B;  1G1Q A;  4JYU L;  4CUE A;  3NTG A;  2VJ3 A;  1YUK B;  2P3F N;  2FD6 A;  3NT1 A;  4A94 C;  1IQF L;  3NTB A;  1FAX L;  4BXW A;  1KIG L;  2W3K B;  3LAQ A;  4RS0 A;  1EMO A;  1L3Y A;  4NGA L;  2J2U B;  5L2Z L;  2J38 B;  1LPK A;  1WU1 B;  4FM5 A;  4BDW A;  1XDT R;  2OYE P;  1CQE A;  1MQ6 L;  1G1S A;  1ATE A;  1LMJ A;  2HOR A;  4BDX A;  3Q7D A;  1M1X B;  2BQ7 A;  1MQ5 L;  1FF7 A;  4X8V L;  2Y7X B;  3OLT A;  1F7E A;  1HAF A;  2BOH A;  1FFM A;  3BPS E;  2PUQ L;  1DX5 I;  6COX A;  1K37 A;  4PH9 A;  1NFY B;  3TGF A;  1URK A;  4LOR A;  3LC3 B;  1V3X B;  3FCS B;  1YGC L;  4BTU A;  3F1S B;  4MMZ B;  1WHE A;  2W86 A;  1IQL L;  2YGP A;  1EMN A;  3FFG L;  2XBX L;  2VVC K;  1SZB A;  2WFX B;  1UZJ A;  4CSY A;  4M11 A;  1LPZ A;  1EZQ B;  4G1M B;  2GD4 A;  2KNI A;  2FLG A;  4JZD L;  4X8U L;  2JKH L;  2W2O E;  4XL1 A;  3EGF A;  1KLJ L;  4OTJ A;  2WPH E;  2XBW L;  2XBY L;  1DIY A;  5CKN A;  3Q3K B;  5IKT A;  3U7U G;  2Y5F L;  2WYJ B;  1FJS L;  3HS5 A;  2Y5G L;  2WPJ E;  1XKB A;  1IGX A;  3V64 C;  1A3P A;  2CJI B;  3CEN L;  2UWP B;  5JBC E;  4Y79 B;  1NPE B;  1ATA A;  1JL9 A;  3S6X A;  1IQN L;  1HAE A;  3MQE A;  4CUF A;  2W2P E;  1LK9 A;  2BZ6 L;  1AUT L;  3CFW A;  1ADX A;  1XFE A;  1X7A L;  5EGM B;  5CKQ A;  5JBB E;  3KQE L;  4GU4 A;  1IOE L;  4M10 A;  4XLW A;  3KL6 B;  4D0E A;  4Z0L A;  1IQJ L;  2WZP P;  2W26 B;  1G2M B;  1J9C L;  2K2T A;  3ZYG A;  4C16 A;  2OYU P;  1CEJ A;  4CUD A;  1EGF A;  3POY A;  1FE2 A;  2DDU A;  1EBV A;  1B9W A;  2YGQ A;  4MMY B;  3SOB B;  3KCG L;  1CCF A;  2M74 A;  1YUG A;  3OLU A;  3CA7 A;  2W2N E;  1NFU B;  2BT8 A;  4JZE L;  1HX2 A;  3HO4 A;  2RNL A;  2B7D L;  2FLB L;  2J34 B;  2J94 B;  4OTY A;  1L5G B;  2MGR A;  2BOK L;  5JW1 A;  1EQH A;  1W8B L;  1Z6E L;  3GCW E;  4BTT A;  5IKV A;  4ISI L;  2J4I B;  1DQB A;  3GCX E;  3MDL A;  2ADX A;  2Y5H L;  3LN0 A;  4ISH L;  2AYL A;  1IQE L;  4RUT A;  1EAI C;  1UZP A;  5E8D A;  1EPG A;  1QIU A;  3KQD L;  2P28 B;  1EQG A;  1V1H A;  2VWN L;  2XC4 L;  5KIR A;  3LTF B;  4BTI A;  4RRW A;  3R05 A;  3QCW A;  5JB8 E;  1C5M F;  3KRK A;  1IQG L;  1RFN B;  1P0S L;  3LC5 B;  3N8X A;  3ZYJ B;  3QMO A;  1NFW B;  2WYG B;  5JVZ A;  5KN5 C;  3N8V A;  1IVO C;  1KLI L;  2F9B L;  1NQL B;  4RRY A;  1YUF A;  1IJQ A;  1PXX A;  1G1T A;  1W7X L;  1U8C B;  2P3T A;  2P94 L;  1FAK L;  3HS6 A;  2BOX A;  5F1A A;  2WPL E;  1UZK A;  1QFK L;  1NFX B;  4YT6 L;  4ZAE B;  4ZXY L;  2RHP A;  4COX A;  1ATD A;  4RRZ A;  3SOV A;  3DEM A;  2W2Q E;  2VVU L;  2KL7 A;  1HRF A;  3ZYI B;  5IKQ A;  3SOQ A;  4YZU B;  4ZXX L;  4RRX A;  3U73 A;  2PR3 B;  2WPM E;  1PGE A;  2P93 L;  2HOX A;  3M36 L;  1APO A;  5JB9 E;  2WG3 C;  4O1Z A;  4X8T L;  2K2S B;  1IQM L;  3PGH A;  1K36 A;  2I9A A;  2G00 L;  1G2L B;  4Y7A B;  4AQT A;  3ASI A;  1NT0 A;  2FZZ L;  1EPJ A;  1HJ7 A;  1F7M A;  1IQI L;  2Y38 A;  4O02 B;  1PFX L;  1DVA L;  1KKE A;  2XBV L;  1Q4G A;  2Q1J B;  3KK6 A;  2W2M E;  4MMX B;  2P3F L;  3TBD A;  3ELA L;  2PHB B;  4JYV L;  1LQD A;  1ATB A;  4NA9 L;  1CCV A;  3IJE B;  1DDX A;  2TGF A;  3HO3 A;  3LN1 A;  5CKM A;  2FLR L;  2NPR A;  2VH0 B;  1JV2 B;  2Y80 B;  2BQW A;  1XKA L;  4GU3 A;  1G1R A;  5L30 L;  2MGP A;  4Y71 B;  1KLO A;  3TZI A;  2P16 L;  2I9B A;  1HT8 A;  4X8S L;  2BO2 A;  1TLE A;  3K9X A;  4Y6D B;  3H5C B;  1O5D L;  4E1G A;  2EI7 B;  4XBM A;  3N8W B;  3IIT B;  1TPG A;  1IGZ A;  1ZAQ A;  3P5B L;  4Y76 B;  3HS7 A;  3TK6 B;  2VVV L;  2JJL A;  1CVU A;  3N8Y B;  1GK5 A;  1EPI A;  3F6U L;  2UWL B;  2VH6 B;  1Z6C A;  3LIW B;  1IOX A;  4YT7 L;  1IQK L;  3GIS X;  1I0U A;  1KSN B;  1YO8 A;  3NJP C;  1BF9 A;  1P9J A;  3TH3 L;  4LMF A;  2EI8 B;  1CX2 A;  5L2Y L;  1UZQ A;  2J95 B;  1HRE A;  5COX A;  2Y81 B;  3SW2 A;  2YGO A;  2Y82 B;  2KB9 A;  4ZH8 B;  1MOX C;  1IQH L;  4TGF A;  5I46 L;  2WPI E;  4D90 A;  2WFT A;  1F0S B;  4Y7B B;  2BSF A;  2BQ6 A;  1HZ8 A;  3N8W A;  1PTH A;  2KV4 A;  3BT1 A;  3BT2 A;  5JBA E;  4BXS A;  1NZI A;  3M37 L;  3KQB L;  1APQ A;  2VWM K;  1U67 A;  1IP0 A;  4JZF L;  1V1I A;  5F19 A;  3TK5 B;  1PRH A;  3HPT A;  3N8Y A;  1LMM A;  2XC0 L;  1F0R B;  2P3U A;  2VWO L;  2XC5 L;  1WHF A;  4A7I A;  1FSB A;  2BT7 A;  3CS7 L;  3KQC L;  3V65 B;  2UWO B;  1HT5 A;  1HCG B;  3HO5 A;  1N1I A;  1OB1 C;  1LPG A;  2P95 L;  5CIS A;  4ZHA B;  2WPK E;  1CVW L; 
#chains in the Genus database with same CATH homology
 2H9E C;  4NG9 L;  2WG4 B;  4Z0K B;  3C9A C;  1COU A;  3QH0 A;  4D0F A;  2EI6 B;  5IKR A;  3N8Z A;  2W3I B;  1EPH A;  2D1J B;  5FDQ A;  5K0H B;  2BOU A;  5JVY A;  2VWL L;  3LTG D;  2H9E L;  3RR3 A;  1TOZ A;  4Z6A L;  3ENS A;  2MHP A;  2RA0 L;  1N7D A;  2P26 A;  2BMG A;  1JBU L;  3FBY A;  2Y7Z B;  1G1Q A;  4JYU L;  4CUE A;  3NTG A;  2VJ3 A;  1YUK B;  2P3F N;  2FD6 A;  3NT1 A;  4A94 C;  1IQF L;  3NTB A;  1FAX L;  4BXW A;  1KIG L;  2W3K B;  3LAQ A;  4RS0 A;  1EMO A;  1L3Y A;  4NGA L;  2J2U B;  5L2Z L;  2J38 B;  1LPK A;  1WU1 B;  4FM5 A;  4BDW A;  1XDT R;  2OYE P;  1CQE A;  1MQ6 L;  1G1S A;  1ATE A;  1LMJ A;  4BDX A;  3Q7D A;  1M1X B;  2BQ7 A;  1MQ5 L;  1FF7 A;  4X8V L;  2Y7X B;  3OLT A;  1F7E A;  1HAF A;  2BOH A;  1FFM A;  3BPS E;  2PUQ L;  1DX5 I;  6COX A;  1K37 A;  4PH9 A;  1NFY B;  3TGF A;  1URK A;  4LOR A;  3LC3 B;  1V3X B;  3FCS B;  1YGC L;  4BTU A;  3F1S B;  4MMZ B;  1WHE A;  2W86 A;  1IQL L;  2YGP A;  1EMN A;  3FFG L;  2XBX L;  2VVC K;  1SZB A;  2WFX B;  1UZJ A;  4CSY A;  4M11 A;  1LPZ A;  1EZQ B;  4G1M B;  2GD4 A;  2KNI A;  2FLG A;  4JZD L;  4X8U L;  2JKH L;  2W2O E;  4XL1 A;  3EGF A;  1KLJ L;  4OTJ A;  2WPH E;  2XBW L;  2XBY L;  1DIY A;  5CKN A;  3Q3K B;  5IKT A;  3U7U G;  2Y5F L;  2WYJ B;  1FJS L;  3HS5 A;  2Y5G L;  2WPJ E;  1XKB A;  1IGX A;  3V64 C;  1A3P A;  2CJI B;  3CEN L;  2UWP B;  5JBC E;  4Y79 B;  1NPE B;  1ATA A;  1JL9 A;  3S6X A;  1IQN L;  1HAE A;  3MQE A;  4CUF A;  2W2P E;  2BZ6 L;  1AUT L;  3CFW A;  1ADX A;  1XFE A;  1X7A L;  5EGM B;  5CKQ A;  5JBB E;  3KQE L;  1IOE L;  4M10 A;  4XLW A;  3KL6 B;  4D0E A;  4Z0L A;  1IQJ L;  2WZP P;  2W26 B;  1G2M B;  1J9C L;  2K2T A;  3ZYG A;  4C16 A;  2OYU P;  1CEJ A;  4CUD A;  1EGF A;  3POY A;  1FE2 A;  2DDU A;  1EBV A;  1B9W A;  2YGQ A;  4MMY B;  3SOB B;  3KCG L;  1CCF A;  2M74 A;  1YUG A;  3OLU A;  3CA7 A;  2W2N E;  1NFU B;  4JZE L;  1HX2 A;  3HO4 A;  2RNL A;  2B7D L;  2FLB L;  2J34 B;  2J94 B;  4OTY A;  1L5G B;  2MGR A;  2BOK L;  5JW1 A;  1EQH A;  1W8B L;  1Z6E L;  3GCW E;  4BTT A;  5IKV A;  4ISI L;  2J4I B;  1DQB A;  3GCX E;  3MDL A;  3LN0 A;  2ADX A;  2Y5H L;  4ISH L;  2AYL A;  1IQE L;  4RUT A;  1EAI C;  1UZP A;  5E8D A;  1EPG A;  3KQD L;  2P28 B;  1EQG A;  2VWN L;  2XC4 L;  5KIR A;  3LTF B;  4BTI A;  4RRW A;  3R05 A;  3QCW A;  5JB8 E;  1C5M F;  3KRK A;  1IQG L;  1RFN B;  1P0S L;  3LC5 B;  3N8X A;  3ZYJ B;  3QMO A;  1NFW B;  2WYG B;  5JVZ A;  5KN5 C;  3N8V A;  1IVO C;  1KLI L;  2F9B L;  1NQL B;  4RRY A;  1YUF A;  1IJQ A;  1PXX A;  1G1T A;  1W7X L;  1U8C B;  2P3T A;  2P94 L;  1FAK L;  3HS6 A;  2BOX A;  5F1A A;  2WPL E;  1UZK A;  1QFK L;  1NFX B;  4YT6 L;  4ZAE B;  4ZXY L;  2RHP A;  4COX A;  1ATD A;  4RRZ A;  3SOV A;  3DEM A;  2W2Q E;  2VVU L;  2KL7 A;  1HRF A;  3ZYI B;  5IKQ A;  3SOQ A;  4YZU B;  4ZXX L;  4RRX A;  3U73 A;  2PR3 B;  2WPM E;  1PGE A;  2P93 L;  3M36 L;  1APO A;  5JB9 E;  2WG3 C;  4O1Z A;  4X8T L;  2K2S B;  1IQM L;  3PGH A;  1K36 A;  2I9A A;  2G00 L;  1G2L B;  4Y7A B;  4AQT A;  3ASI A;  1NT0 A;  2FZZ L;  1EPJ A;  1HJ7 A;  1F7M A;  1IQI L;  2Y38 A;  4O02 B;  1PFX L;  1DVA L;  2XBV L;  1Q4G A;  2Q1J B;  3KK6 A;  2W2M E;  4MMX B;  2P3F L;  3TBD A;  3ELA L;  2PHB B;  4JYV L;  1LQD A;  1ATB A;  4NA9 L;  1CCV A;  3IJE B;  1DDX A;  2TGF A;  3HO3 A;  3LN1 A;  5CKM A;  2FLR L;  2NPR A;  2VH0 B;  1JV2 B;  2Y80 B;  2BQW A;  1XKA L;  1G1R A;  5L30 L;  2MGP A;  4Y71 B;  1KLO A;  3TZI A;  2P16 L;  2I9B A;  1HT8 A;  4X8S L;  2BO2 A;  1TLE A;  3K9X A;  4Y6D B;  3H5C B;  1O5D L;  4E1G A;  2EI7 B;  4XBM A;  3N8W B;  3IIT B;  1TPG A;  1IGZ A;  1ZAQ A;  3P5B L;  4Y76 B;  3HS7 A;  3TK6 B;  2VVV L;  1CVU A;  3N8Y B;  1GK5 A;  1EPI A;  3F6U L;  2UWL B;  2VH6 B;  1Z6C A;  3LIW B;  1IOX A;  4YT7 L;  1IQK L;  3GIS X;  1I0U A;  1KSN B;  1YO8 A;  3NJP C;  1BF9 A;  1P9J A;  3TH3 L;  4LMF A;  2EI8 B;  1CX2 A;  5L2Y L;  1UZQ A;  2J95 B;  1HRE A;  5COX A;  2Y81 B;  3SW2 A;  2YGO A;  2Y82 B;  2KB9 A;  4ZH8 B;  1MOX C;  1IQH L;  4TGF A;  5I46 L;  2WPI E;  4D90 A;  2WFT A;  1F0S B;  4Y7B B;  2BQ6 A;  1HZ8 A;  3N8W A;  1PTH A;  2KV4 A;  3BT1 A;  3BT2 A;  5JBA E;  4BXS A;  1NZI A;  3M37 L;  3KQB L;  1APQ A;  2VWM K;  1U67 A;  1IP0 A;  4JZF L;  5F19 A;  3TK5 B;  1PRH A;  3HPT A;  3N8Y A;  1LMM A;  1F0R B;  2P3U A;  2XC0 L;  2VWO L;  2XC5 L;  1WHF A;  4A7I A;  1FSB A;  3CS7 L;  3KQC L;  3V65 B;  2UWO B;  1HT5 A;  1HCG B;  3HO5 A;  1N1I A;  1OB1 C;  1LPG A;  2P95 L;  5CIS A;  4ZHA B;  2WPK E;  1CVW L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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