3J7AD

Cryo-em structure of the plasmodium falciparum 80s ribosome bound to the anti-protozoan drug emetine, small subunit
Total Genus 36

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
209
structure length
157
Chain Sequence
PISKKRKFINDGVFQAELNEFLARILAEDGYSGVEVRIRELTSLVQKRFFLCAMAQAESLRYKLLKGLAVRRACYGVLRHIMESGAKGCEVIVSGKLRAQRAKSMKFRDGYLISTGEPSKRFVNTATRSAQLKQGVLGIKVKIMLPTSILPDNISVL
2040608010012014014012010080604020
05101520253035Genus Matrix

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
AH1 (7-28)TI1 (29-32)EMPTYS1 (134-141)TIV1 (132-135)AH4 (117-130)TIV2 (142-145)AH3 (99-112)AH2 (65-77)Updating...
connected with : NaN
molecule tags Ribosome/inhibitor
publication title Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
pubmed doi rcsb
molecule keywords 18S ribosomal RNA
total genus 36
structure length 157
sequence length 209
ec nomenclature
pdb deposition date 2014-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00189 Ribosomal_S3_C Ribosomal protein S3, C-terminal domain
D PF07650 KH_2 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1140.32 Alpha Beta 2-Layer Sandwich Ribosomal protein S3 C-terminal domain Ribosomal protein S3, C-terminal domain 3j7aD01
3OTOC 4K0KC 3J7AD 4JI1C 3J81D 4LF6C 2F4VC 4NXMC 4JI4C 1IBLC 1N32C 1XMOC 5LMNC 5A2QD 2HHHC 4DUYC 4B3RC 1XNRC 4B3SC 1N34C 4LFAC 4X65C 1HR0C 4DR2C 2UU9C 4NXNC 4JI0C 5FLXD 1N33C 4AQYC 2E5LC 1N36C 4DV0C 5BR8C 1XNQC 4JI3C 2ZM6C 4B3TC 4DR6C 2UXBC 4JI2C 1HNWC 5IT9D 4JI7C 1XMQC 1HNXC 4OX9C 4JI5C 1IBMC 1J5EC 4LF4C 4LF5C 4DR5C 2VQFC 4DV6C 4DUZC 4GKJC 2UUBC 3JAMD 4DV2C 4DV1C 4DR1C 4JV5C 4JYAC 4GKKC 4YHHC 1HNZC 4LF7C 4DR3C 4B3MC 4DV5C 5LMUC 4X66C 4BSZA 3T1YC 1I94C 4DR7C 4DR4C 4YY3C 5IWAC 4LFCC 3J80D 1IBKC 2UUCC 3T1HC 4KHPC 4X64C 4JI6C 4LF9C 2VQEC 2UUAC 2UXDC 4X62C 4DV7C 4LFBC 1FJGC 4JI8C 2UXCC 4DV4C 4DV3C 4LF8C
chains in the Genus database with same CATH superfamily
3OTOC 4K0KC 1XDXA 3J7AD 4JI1C 3J81D 4LF6C 2F4VC 4NXMC 4JI4C 1IBLC 1N32C 1XMOC 5LMNC 5A2QD 2HHHC 4DUYC 4B3RC 1XNRC 4B3SC 1N34C 2ZTBA 4LFAC 4X65C 1HR0C 4DR2C 2UU9C 4NXNC 2PG1E 3FM7A 4JI0C 5FLXD 1N33C 4AQYC 2E5LC 1N36C 4DV0C 5BR8C 1XNQC 4JI3C 2ZM6C 4B3TC 4DR6C 2UXBC 4JI2C 1HNWC 5IT9D 4JI7C 1XMQC 1HNXC 4OX9C 4JI5C 1IBMC 1J5EC 4LF4C 4LF5C 4DR5C 2VQFC 4DV6C 4DUZC 4GKJC 2UUBC 3JAMD 4DV2C 4DV1C 4DR1C 4JV5C 4JYAC 4GKKC 4YHHC 1HNZC 4LF7C 4DR3C 4B3MC 4DV5C 5LMUC 4X66C 4BSZA 3T1YC 1I94C 4DR7C 4DR4C 4YY3C 5IWAC 4LFCC 3J80D 1IBKC 2UUCC 3T1HC 4KHPC 4X64C 4JI6C 4LF9C 2VQEC 2UUAC 2UXDC 4X62C 4DV7C 4LFBC 1FJGC 4JI8C 2UXCC 1YGTA 4DV4C 4DV3C 4LF8C
chains in the Genus database with same CATH topology
3OTOC 4K0KC 3J7AD 4JI1C 3J81D 4LF6C 2F4VC 4NXMC 4JI4C 1IBLC 1N32C 1XMOC 5LMNC 5A2QD 2HHHC 4DUYC 4B3RC 1XNRC 4B3SC 1N34C 4LFAC 4X65C 1HR0C 4DR2C 2UU9C 4NXNC 4JI0C 5FLXD 1N33C 4AQYC 2E5LC 1N36C 4DV0C 5BR8C 1XNQC 4JI3C 2ZM6C 4B3TC 4DR6C 2UXBC 4JI2C 1HNWC 5IT9D 4JI7C 1XMQC 1HNXC 4OX9C 4JI5C 1IBMC 1J5EC 4LF4C 4LF5C 4DR5C 2VQFC 4DV6C 4DUZC 4GKJC 2UUBC 3JAMD 4DV2C 4DV1C 4DR1C 4JV5C 4JYAC 4GKKC 4YHHC 1HNZC 4LF7C 4DR3C 4B3MC 4DV5C 5LMUC 4X66C 4BSZA 3T1YC 1I94C 4DR7C 4DR4C 4YY3C 5IWAC 4LFCC 3J80D 1IBKC 2UUCC 3T1HC 4KHPC 4X64C 4JI6C 4LF9C 2VQEC 2UUAC 2UXDC 4X62C 4DV7C 4LFBC 1FJGC 4JI8C 2UXCC 4DV4C 4DV3C 4LF8C
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3OTO C;  4K0K C;  3J7A D;  4JI1 C;  3J81 D;  4LF6 C;  2F4V C;  4NXM C;  4JI4 C;  1IBL C;  1N32 C;  1XMO C;  5LMN C;  5A2Q D;  2HHH C;  4DUY C;  4B3R C;  1XNR C;  4B3S C;  1N34 C;  4LFA C;  4X65 C;  1HR0 C;  4DR2 C;  2UU9 C;  4NXN C;  4JI0 C;  5FLX D;  1N33 C;  4AQY C;  2E5L C;  1N36 C;  4DV0 C;  5BR8 C;  1XNQ C;  4JI3 C;  2ZM6 C;  4B3T C;  4DR6 C;  2UXB C;  4JI2 C;  1HNW C;  5IT9 D;  4JI7 C;  1XMQ C;  1HNX C;  4OX9 C;  4JI5 C;  1IBM C;  1J5E C;  4LF4 C;  4LF5 C;  4DR5 C;  2VQF C;  4DV6 C;  4DUZ C;  4GKJ C;  2UUB C;  3JAM D;  4DV2 C;  4DV1 C;  4DR1 C;  4JV5 C;  4JYA C;  4GKK C;  4YHH C;  1HNZ C;  4LF7 C;  4DR3 C;  4B3M C;  4DV5 C;  5LMU C;  4X66 C;  4BSZ A;  3T1Y C;  1I94 C;  4DR7 C;  4DR4 C;  4YY3 C;  5IWA C;  4LFC C;  3J80 D;  1IBK C;  2UUC C;  3T1H C;  4KHP C;  4X64 C;  4JI6 C;  4LF9 C;  2VQE C;  2UUA C;  2UXD C;  4X62 C;  4DV7 C;  4LFB C;  1FJG C;  4JI8 C;  2UXC C;  4DV4 C;  4DV3 C;  4LF8 C; 
#chains in the Genus database with same CATH topology
 3OTO C;  4K0K C;  1XDX A;  3J7A D;  4JI1 C;  3J81 D;  4LF6 C;  2F4V C;  4NXM C;  4JI4 C;  1IBL C;  1N32 C;  1XMO C;  5LMN C;  5A2Q D;  2HHH C;  4DUY C;  4B3R C;  1XNR C;  4B3S C;  1N34 C;  2ZTB A;  4LFA C;  4X65 C;  1HR0 C;  4DR2 C;  2UU9 C;  4NXN C;  2PG1 E;  3FM7 A;  4JI0 C;  5FLX D;  1N33 C;  4AQY C;  2E5L C;  1N36 C;  4DV0 C;  5BR8 C;  1XNQ C;  4JI3 C;  2ZM6 C;  4B3T C;  4DR6 C;  2UXB C;  4JI2 C;  1HNW C;  5IT9 D;  4JI7 C;  1XMQ C;  1HNX C;  4OX9 C;  4JI5 C;  1IBM C;  1J5E C;  4LF4 C;  4LF5 C;  4DR5 C;  2VQF C;  4DV6 C;  4DUZ C;  4GKJ C;  2UUB C;  3JAM D;  4DV2 C;  4DV1 C;  4DR1 C;  4JV5 C;  4JYA C;  4GKK C;  4YHH C;  1HNZ C;  4LF7 C;  4DR3 C;  4B3M C;  4DV5 C;  5LMU C;  4X66 C;  4BSZ A;  3T1Y C;  1I94 C;  4DR7 C;  4DR4 C;  4YY3 C;  5IWA C;  4LFC C;  3J80 D;  1IBK C;  2UUC C;  3T1H C;  4KHP C;  4X64 C;  4JI6 C;  4LF9 C;  2VQE C;  2UUA C;  2UXD C;  4X62 C;  4DV7 C;  4LFB C;  1FJG C;  4JI8 C;  2UXC C;  1YGT A;  4DV4 C;  4DV3 C;  4LF8 C; 
#chains in the Genus database with same CATH homology
 3OTO C;  4K0K C;  3J7A D;  4JI1 C;  3J81 D;  4LF6 C;  2F4V C;  4NXM C;  4JI4 C;  1IBL C;  1N32 C;  1XMO C;  5LMN C;  5A2Q D;  2HHH C;  4DUY C;  4B3R C;  1XNR C;  4B3S C;  1N34 C;  4LFA C;  4X65 C;  1HR0 C;  4DR2 C;  2UU9 C;  4NXN C;  4JI0 C;  5FLX D;  1N33 C;  4AQY C;  2E5L C;  1N36 C;  4DV0 C;  5BR8 C;  1XNQ C;  4JI3 C;  2ZM6 C;  4B3T C;  4DR6 C;  2UXB C;  4JI2 C;  1HNW C;  5IT9 D;  4JI7 C;  1XMQ C;  1HNX C;  4OX9 C;  4JI5 C;  1IBM C;  1J5E C;  4LF4 C;  4LF5 C;  4DR5 C;  2VQF C;  4DV6 C;  4DUZ C;  4GKJ C;  2UUB C;  3JAM D;  4DV2 C;  4DV1 C;  4DR1 C;  4JV5 C;  4JYA C;  4GKK C;  4YHH C;  1HNZ C;  4LF7 C;  4DR3 C;  4B3M C;  4DV5 C;  5LMU C;  4X66 C;  4BSZ A;  3T1Y C;  1I94 C;  4DR7 C;  4DR4 C;  4YY3 C;  5IWA C;  4LFC C;  3J80 D;  1IBK C;  2UUC C;  3T1H C;  4KHP C;  4X64 C;  4JI6 C;  4LF9 C;  2VQE C;  2UUA C;  2UXD C;  4X62 C;  4DV7 C;  4LFB C;  1FJG C;  4JI8 C;  2UXC C;  4DV4 C;  4DV3 C;  4LF8 C;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite
Application loaded.