3J7AD

Cryo-em structure of the plasmodium falciparum 80s ribosome bound to the anti-protozoan drug emetine, small subunit
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
209
structure length
157
Chain Sequence
PISKKRKFINDGVFQAELNEFLARILAEDGYSGVEVRIRELTSLVQKRFFLCAMAQAESLRYKLLKGLAVRRACYGVLRHIMESGAKGCEVIVSGKLRAQRAKSMKFRDGYLISTGEPSKRFVNTATRSAQLKQGVLGIKVKIMLPTSILPDNISVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
pubmed doi rcsb
molecule tags Ribosome/inhibitor
molecule keywords 18S ribosomal RNA
total genus 36
structure length 157
sequence length 209
ec nomenclature
pdb deposition date 2014-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00189 Ribosomal_S3_C Ribosomal protein S3, C-terminal domain
D PF07650 KH_2 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1140.32 Alpha Beta 2-Layer Sandwich Ribosomal protein S3 C-terminal domain Ribosomal protein S3, C-terminal domain 3j7aD01
2HHHC 3J81D 1N34C 5IWAC 4OX9C 2ZM6C 1XMQC 5A2QD 2UUBC 4LF4C 2VQEC 2UXBC 1J5EC 4X64C 4DR6C 4JI2C 1IBKC 1I94C 4KHPC 1HNXC 4LF9C 4B3SC 4JI8C 1HNWC 4DR1C 4DV6C 4B3RC 4DR3C 1HNZC 4JI1C 4JYAC 3T1YC 4X65C 2VQFC 4YHHC 3OTOC 2UUCC 4LF5C 4X66C 4B3TC 4LFBC 4DV1C 4NXMC 3T1HC 4GKJC 4DV5C 3J7AD 4B3MC 4DV4C 4AQYC 4JI6C 4LF6C 5BR8C 1N32C 4JI5C 4DR2C 3J80D 4JI0C 1IBMC 4K0KC 4LF7C 4LFCC 4DUYC 1XMOC 4NXNC 1IBLC 4JI3C 4LFAC 4GKKC 4JI4C 1XNQC 2UXDC 1N36C 2UU9C 2F4VC 4JV5C 4DV7C 4BSZA 5LMNC 4DR5C 1HR0C 1N33C 4JI7C 5IT9D 4YY3C 4DV0C 4LF8C 4DV2C 4DUZC 4DR7C 1XNRC 4DR4C 3JAMD 5FLXD 2UXCC 5LMUC 4DV3C 4X62C 1FJGC 2E5LC 2UUAC
chains in the Genus database with same CATH superfamily
2HHHC 3J81D 1N34C 5IWAC 4OX9C 2ZM6C 1XMQC 5A2QD 2UUBC 4LF4C 2VQEC 2UXBC 1YGTA 1J5EC 4X64C 4DR6C 1XDXA 4JI2C 1IBKC 1I94C 4KHPC 1HNXC 4LF9C 4B3SC 4JI8C 1HNWC 4DR1C 4DV6C 4B3RC 4DR3C 1HNZC 4JI1C 2PG1E 4JYAC 3T1YC 4X65C 2VQFC 4YHHC 3OTOC 2UUCC 4LF5C 2ZTBA 4X66C 3FM7A 4B3TC 4LFBC 4DV1C 4NXMC 3T1HC 4GKJC 4DV5C 3J7AD 4B3MC 4DV4C 4AQYC 4JI6C 4LF6C 5BR8C 1N32C 4JI5C 4DR2C 3J80D 4JI0C 1IBMC 4K0KC 4LF7C 4LFCC 4DUYC 1XMOC 4NXNC 1IBLC 4JI3C 4LFAC 4GKKC 4JI4C 1XNQC 2UXDC 1N36C 2UU9C 2F4VC 4JV5C 4DV7C 4BSZA 5LMNC 4DR5C 1HR0C 1N33C 4JI7C 5IT9D 4YY3C 4DV0C 4LF8C 4DV2C 4DUZC 4DR7C 1XNRC 4DR4C 3JAMD 5FLXD 2UXCC 5LMUC 4DV3C 4X62C 1FJGC 2E5LC 2UUAC
chains in the Genus database with same CATH topology
2HHHC 3J81D 1N34C 5IWAC 4OX9C 2ZM6C 1XMQC 5A2QD 2UUBC 4LF4C 2VQEC 2UXBC 1J5EC 4X64C 4DR6C 4JI2C 1IBKC 1I94C 4KHPC 1HNXC 4LF9C 4B3SC 4JI8C 1HNWC 4DR1C 4DV6C 4B3RC 4DR3C 1HNZC 4JI1C 4JYAC 3T1YC 4X65C 2VQFC 4YHHC 3OTOC 2UUCC 4LF5C 4X66C 4B3TC 4LFBC 4DV1C 4NXMC 3T1HC 4GKJC 4DV5C 3J7AD 4B3MC 4DV4C 4AQYC 4JI6C 4LF6C 5BR8C 1N32C 4JI5C 4DR2C 3J80D 4JI0C 1IBMC 4K0KC 4LF7C 4LFCC 4DUYC 1XMOC 4NXNC 1IBLC 4JI3C 4LFAC 4GKKC 4JI4C 1XNQC 2UXDC 1N36C 2UU9C 2F4VC 4JV5C 4DV7C 4BSZA 5LMNC 4DR5C 1HR0C 1N33C 4JI7C 5IT9D 4YY3C 4DV0C 4LF8C 4DV2C 4DUZC 4DR7C 1XNRC 4DR4C 3JAMD 5FLXD 2UXCC 5LMUC 4DV3C 4X62C 1FJGC 2E5LC 2UUAC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HHH C;  3J81 D;  1N34 C;  5IWA C;  4OX9 C;  2ZM6 C;  1XMQ C;  5A2Q D;  2UUB C;  4LF4 C;  2VQE C;  2UXB C;  1J5E C;  4X64 C;  4DR6 C;  4JI2 C;  1IBK C;  1I94 C;  4KHP C;  1HNX C;  4LF9 C;  4B3S C;  4JI8 C;  1HNW C;  4DR1 C;  4DV6 C;  4B3R C;  4DR3 C;  1HNZ C;  4JI1 C;  4JYA C;  3T1Y C;  4X65 C;  2VQF C;  4YHH C;  3OTO C;  2UUC C;  4LF5 C;  4X66 C;  4B3T C;  4LFB C;  4DV1 C;  4NXM C;  3T1H C;  4GKJ C;  4DV5 C;  3J7A D;  4B3M C;  4DV4 C;  4AQY C;  4JI6 C;  4LF6 C;  5BR8 C;  1N32 C;  4JI5 C;  4DR2 C;  3J80 D;  4JI0 C;  1IBM C;  4K0K C;  4LF7 C;  4LFC C;  4DUY C;  1XMO C;  4NXN C;  1IBL C;  4JI3 C;  4LFA C;  4GKK C;  4JI4 C;  1XNQ C;  2UXD C;  1N36 C;  2UU9 C;  2F4V C;  4JV5 C;  4DV7 C;  4BSZ A;  5LMN C;  4DR5 C;  1HR0 C;  1N33 C;  4JI7 C;  5IT9 D;  4YY3 C;  4DV0 C;  4LF8 C;  4DV2 C;  4DUZ C;  4DR7 C;  1XNR C;  4DR4 C;  3JAM D;  5FLX D;  2UXC C;  5LMU C;  4DV3 C;  4X62 C;  1FJG C;  2E5L C;  2UUA C; 
#chains in the Genus database with same CATH topology
 2HHH C;  3J81 D;  1N34 C;  5IWA C;  4OX9 C;  2ZM6 C;  1XMQ C;  5A2Q D;  2UUB C;  4LF4 C;  2VQE C;  2UXB C;  1YGT A;  1J5E C;  4X64 C;  4DR6 C;  1XDX A;  4JI2 C;  1IBK C;  1I94 C;  4KHP C;  1HNX C;  4LF9 C;  4B3S C;  4JI8 C;  1HNW C;  4DR1 C;  4DV6 C;  4B3R C;  4DR3 C;  1HNZ C;  4JI1 C;  2PG1 E;  4JYA C;  3T1Y C;  4X65 C;  2VQF C;  4YHH C;  3OTO C;  2UUC C;  4LF5 C;  2ZTB A;  4X66 C;  3FM7 A;  4B3T C;  4LFB C;  4DV1 C;  4NXM C;  3T1H C;  4GKJ C;  4DV5 C;  3J7A D;  4B3M C;  4DV4 C;  4AQY C;  4JI6 C;  4LF6 C;  5BR8 C;  1N32 C;  4JI5 C;  4DR2 C;  3J80 D;  4JI0 C;  1IBM C;  4K0K C;  4LF7 C;  4LFC C;  4DUY C;  1XMO C;  4NXN C;  1IBL C;  4JI3 C;  4LFA C;  4GKK C;  4JI4 C;  1XNQ C;  2UXD C;  1N36 C;  2UU9 C;  2F4V C;  4JV5 C;  4DV7 C;  4BSZ A;  5LMN C;  4DR5 C;  1HR0 C;  1N33 C;  4JI7 C;  5IT9 D;  4YY3 C;  4DV0 C;  4LF8 C;  4DV2 C;  4DUZ C;  4DR7 C;  1XNR C;  4DR4 C;  3JAM D;  5FLX D;  2UXC C;  5LMU C;  4DV3 C;  4X62 C;  1FJG C;  2E5L C;  2UUA C; 
#chains in the Genus database with same CATH homology
 2HHH C;  3J81 D;  1N34 C;  5IWA C;  4OX9 C;  2ZM6 C;  1XMQ C;  5A2Q D;  2UUB C;  4LF4 C;  2VQE C;  2UXB C;  1J5E C;  4X64 C;  4DR6 C;  4JI2 C;  1IBK C;  1I94 C;  4KHP C;  1HNX C;  4LF9 C;  4B3S C;  4JI8 C;  1HNW C;  4DR1 C;  4DV6 C;  4B3R C;  4DR3 C;  1HNZ C;  4JI1 C;  4JYA C;  3T1Y C;  4X65 C;  2VQF C;  4YHH C;  3OTO C;  2UUC C;  4LF5 C;  4X66 C;  4B3T C;  4LFB C;  4DV1 C;  4NXM C;  3T1H C;  4GKJ C;  4DV5 C;  3J7A D;  4B3M C;  4DV4 C;  4AQY C;  4JI6 C;  4LF6 C;  5BR8 C;  1N32 C;  4JI5 C;  4DR2 C;  3J80 D;  4JI0 C;  1IBM C;  4K0K C;  4LF7 C;  4LFC C;  4DUY C;  1XMO C;  4NXN C;  1IBL C;  4JI3 C;  4LFA C;  4GKK C;  4JI4 C;  1XNQ C;  2UXD C;  1N36 C;  2UU9 C;  2F4V C;  4JV5 C;  4DV7 C;  4BSZ A;  5LMN C;  4DR5 C;  1HR0 C;  1N33 C;  4JI7 C;  5IT9 D;  4YY3 C;  4DV0 C;  4LF8 C;  4DV2 C;  4DUZ C;  4DR7 C;  1XNR C;  4DR4 C;  3JAM D;  5FLX D;  2UXC C;  5LMU C;  4DV3 C;  4X62 C;  1FJG C;  2E5L C;  2UUA C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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