3J7AD

Cryo-em structure of the plasmodium falciparum 80s ribosome bound to the anti-protozoan drug emetine, small subunit
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
209
structure length
157
Chain Sequence
PISKKRKFINDGVFQAELNEFLARILAEDGYSGVEVRIRELTSLVQKRFFLCAMAQAESLRYKLLKGLAVRRACYGVLRHIMESGAKGCEVIVSGKLRAQRAKSMKFRDGYLISTGEPSKRFVNTATRSAQLKQGVLGIKVKIMLPTSILPDNISVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
pubmed doi rcsb
molecule tags Ribosome/inhibitor
molecule keywords 18S ribosomal RNA
total genus 36
structure length 157
sequence length 209
ec nomenclature
pdb deposition date 2014-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00189 Ribosomal_S3_C Ribosomal protein S3, C-terminal domain
D PF07650 KH_2 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1140.32 Alpha Beta 2-Layer Sandwich Ribosomal protein S3 C-terminal domain Ribosomal protein S3, C-terminal domain 3j7aD01
4B3TC 1FJGC 4JI6C 2UXBC 4DV6C 3J81D 4KHPC 2UXCC 3OTOC 3T1HC 2UU9C 4LF8C 4LFAC 2UUBC 1N34C 4DR5C 4DV5C 4DV7C 4B3SC 1XNRC 4K0KC 4JI1C 1IBMC 1N36C 3T1YC 4LF6C 4LFBC 4X62C 2VQEC 4NXMC 4B3MC 2VQFC 4DV0C 5LMUC 2UUAC 4DR6C 4DR3C 4DUZC 4JYAC 4JI2C 4DV3C 4JV5C 2HHHC 5LMNC 5FLXD 4YY3C 4DR2C 1HNXC 1HR0C 4DV1C 1HNWC 4LF4C 4YHHC 4B3RC 1N33C 4BSZA 2UUCC 2UXDC 1XMOC 4X64C 5BR8C 4GKKC 4NXNC 4JI7C 4DR7C 4JI4C 2F4VC 1N32C 5IT9D 1IBKC 1I94C 3J7AD 2E5LC 4LF7C 3J80D 4GKJC 4AQYC 1IBLC 4JI5C 4DV4C 4DR4C 1XMQC 1XNQC 5A2QD 4DR1C 4JI0C 1HNZC 4DV2C 4LF5C 4LFCC 4DUYC 2ZM6C 5IWAC 1J5EC 4LF9C 4X66C 3JAMD 4OX9C 4X65C 4JI8C 4JI3C
chains in the Genus database with same CATH superfamily
4B3TC 1FJGC 4JI6C 2UXBC 4DV6C 3J81D 4KHPC 2UXCC 1YGTA 3OTOC 3T1HC 2UU9C 4LF8C 3FM7A 4LFAC 2UUBC 1N34C 4DR5C 2PG1E 4DV5C 4DV7C 4B3SC 1XNRC 4K0KC 4JI1C 1IBMC 1N36C 3T1YC 2ZTBA 4LF6C 4LFBC 4X62C 2VQEC 4NXMC 4B3MC 2VQFC 4DV0C 5LMUC 2UUAC 4DR6C 4DR3C 4DUZC 4JYAC 4JI2C 4DV3C 4JV5C 2HHHC 5LMNC 5FLXD 4YY3C 4DR2C 1HNXC 1HR0C 4DV1C 1HNWC 4LF4C 4YHHC 4B3RC 1N33C 4BSZA 2UUCC 2UXDC 1XMOC 4X64C 5BR8C 4GKKC 4NXNC 4JI7C 4DR7C 4JI4C 2F4VC 1N32C 5IT9D 1IBKC 1I94C 3J7AD 2E5LC 1XDXA 4LF7C 3J80D 4GKJC 4AQYC 1IBLC 4JI5C 4DV4C 4DR4C 1XMQC 1XNQC 5A2QD 4DR1C 4JI0C 1HNZC 4DV2C 4LF5C 4LFCC 4DUYC 2ZM6C 5IWAC 1J5EC 4LF9C 4X66C 3JAMD 4OX9C 4X65C 4JI8C 4JI3C
chains in the Genus database with same CATH topology
4B3TC 1FJGC 4JI6C 2UXBC 4DV6C 3J81D 4KHPC 2UXCC 3OTOC 3T1HC 2UU9C 4LF8C 4LFAC 2UUBC 1N34C 4DR5C 4DV5C 4DV7C 4B3SC 1XNRC 4K0KC 4JI1C 1IBMC 1N36C 3T1YC 4LF6C 4LFBC 4X62C 2VQEC 4NXMC 4B3MC 2VQFC 4DV0C 5LMUC 2UUAC 4DR6C 4DR3C 4DUZC 4JYAC 4JI2C 4DV3C 4JV5C 2HHHC 5LMNC 5FLXD 4YY3C 4DR2C 1HNXC 1HR0C 4DV1C 1HNWC 4LF4C 4YHHC 4B3RC 1N33C 4BSZA 2UUCC 2UXDC 1XMOC 4X64C 5BR8C 4GKKC 4NXNC 4JI7C 4DR7C 4JI4C 2F4VC 1N32C 5IT9D 1IBKC 1I94C 3J7AD 2E5LC 4LF7C 3J80D 4GKJC 4AQYC 1IBLC 4JI5C 4DV4C 4DR4C 1XMQC 1XNQC 5A2QD 4DR1C 4JI0C 1HNZC 4DV2C 4LF5C 4LFCC 4DUYC 2ZM6C 5IWAC 1J5EC 4LF9C 4X66C 3JAMD 4OX9C 4X65C 4JI8C 4JI3C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4B3T C;  1FJG C;  4JI6 C;  2UXB C;  4DV6 C;  3J81 D;  4KHP C;  2UXC C;  3OTO C;  3T1H C;  2UU9 C;  4LF8 C;  4LFA C;  2UUB C;  1N34 C;  4DR5 C;  4DV5 C;  4DV7 C;  4B3S C;  1XNR C;  4K0K C;  4JI1 C;  1IBM C;  1N36 C;  3T1Y C;  4LF6 C;  4LFB C;  4X62 C;  2VQE C;  4NXM C;  4B3M C;  2VQF C;  4DV0 C;  5LMU C;  2UUA C;  4DR6 C;  4DR3 C;  4DUZ C;  4JYA C;  4JI2 C;  4DV3 C;  4JV5 C;  2HHH C;  5LMN C;  5FLX D;  4YY3 C;  4DR2 C;  1HNX C;  1HR0 C;  4DV1 C;  1HNW C;  4LF4 C;  4YHH C;  4B3R C;  1N33 C;  4BSZ A;  2UUC C;  2UXD C;  1XMO C;  4X64 C;  5BR8 C;  4GKK C;  4NXN C;  4JI7 C;  4DR7 C;  4JI4 C;  2F4V C;  1N32 C;  5IT9 D;  1IBK C;  1I94 C;  3J7A D;  2E5L C;  4LF7 C;  3J80 D;  4GKJ C;  4AQY C;  1IBL C;  4JI5 C;  4DV4 C;  4DR4 C;  1XMQ C;  1XNQ C;  5A2Q D;  4DR1 C;  4JI0 C;  1HNZ C;  4DV2 C;  4LF5 C;  4LFC C;  4DUY C;  2ZM6 C;  5IWA C;  1J5E C;  4LF9 C;  4X66 C;  3JAM D;  4OX9 C;  4X65 C;  4JI8 C;  4JI3 C; 
#chains in the Genus database with same CATH topology
 4B3T C;  1FJG C;  4JI6 C;  2UXB C;  4DV6 C;  3J81 D;  4KHP C;  2UXC C;  1YGT A;  3OTO C;  3T1H C;  2UU9 C;  4LF8 C;  3FM7 A;  4LFA C;  2UUB C;  1N34 C;  4DR5 C;  2PG1 E;  4DV5 C;  4DV7 C;  4B3S C;  1XNR C;  4K0K C;  4JI1 C;  1IBM C;  1N36 C;  3T1Y C;  2ZTB A;  4LF6 C;  4LFB C;  4X62 C;  2VQE C;  4NXM C;  4B3M C;  2VQF C;  4DV0 C;  5LMU C;  2UUA C;  4DR6 C;  4DR3 C;  4DUZ C;  4JYA C;  4JI2 C;  4DV3 C;  4JV5 C;  2HHH C;  5LMN C;  5FLX D;  4YY3 C;  4DR2 C;  1HNX C;  1HR0 C;  4DV1 C;  1HNW C;  4LF4 C;  4YHH C;  4B3R C;  1N33 C;  4BSZ A;  2UUC C;  2UXD C;  1XMO C;  4X64 C;  5BR8 C;  4GKK C;  4NXN C;  4JI7 C;  4DR7 C;  4JI4 C;  2F4V C;  1N32 C;  5IT9 D;  1IBK C;  1I94 C;  3J7A D;  2E5L C;  1XDX A;  4LF7 C;  3J80 D;  4GKJ C;  4AQY C;  1IBL C;  4JI5 C;  4DV4 C;  4DR4 C;  1XMQ C;  1XNQ C;  5A2Q D;  4DR1 C;  4JI0 C;  1HNZ C;  4DV2 C;  4LF5 C;  4LFC C;  4DUY C;  2ZM6 C;  5IWA C;  1J5E C;  4LF9 C;  4X66 C;  3JAM D;  4OX9 C;  4X65 C;  4JI8 C;  4JI3 C; 
#chains in the Genus database with same CATH homology
 4B3T C;  1FJG C;  4JI6 C;  2UXB C;  4DV6 C;  3J81 D;  4KHP C;  2UXC C;  3OTO C;  3T1H C;  2UU9 C;  4LF8 C;  4LFA C;  2UUB C;  1N34 C;  4DR5 C;  4DV5 C;  4DV7 C;  4B3S C;  1XNR C;  4K0K C;  4JI1 C;  1IBM C;  1N36 C;  3T1Y C;  4LF6 C;  4LFB C;  4X62 C;  2VQE C;  4NXM C;  4B3M C;  2VQF C;  4DV0 C;  5LMU C;  2UUA C;  4DR6 C;  4DR3 C;  4DUZ C;  4JYA C;  4JI2 C;  4DV3 C;  4JV5 C;  2HHH C;  5LMN C;  5FLX D;  4YY3 C;  4DR2 C;  1HNX C;  1HR0 C;  4DV1 C;  1HNW C;  4LF4 C;  4YHH C;  4B3R C;  1N33 C;  4BSZ A;  2UUC C;  2UXD C;  1XMO C;  4X64 C;  5BR8 C;  4GKK C;  4NXN C;  4JI7 C;  4DR7 C;  4JI4 C;  2F4V C;  1N32 C;  5IT9 D;  1IBK C;  1I94 C;  3J7A D;  2E5L C;  4LF7 C;  3J80 D;  4GKJ C;  4AQY C;  1IBL C;  4JI5 C;  4DV4 C;  4DR4 C;  1XMQ C;  1XNQ C;  5A2Q D;  4DR1 C;  4JI0 C;  1HNZ C;  4DV2 C;  4LF5 C;  4LFC C;  4DUY C;  2ZM6 C;  5IWA C;  1J5E C;  4LF9 C;  4X66 C;  3JAM D;  4OX9 C;  4X65 C;  4JI8 C;  4JI3 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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