1H3IA

Crystal structure of the histone methyltransferase set7/9
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
293
structure length
293
Chain Sequence
FFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHSPPGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords HISTONE H3 LYSINE 4 SPECIFIC METHYLTRANSFERASE
publication title Crystal Structure and Functional Analysis of the Histone Methyltransferase Set7/9
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 71
structure length 293
sequence length 293
chains with identical sequence B
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-09-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF02493 MORN MORN repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.110.10 Mainly Beta Single Sheet Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 1h3iA01
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1h3iA02
4MI5A 1MVHA 2O8JA 4BUPA 1H3IA 2QPWA 3TG4A 4I51A 5EX0A 2G46A 3S7FA 3RJWA 4O30A 3CBOA 5LSZA 5JHNA 1MVXA 3M57A 5HI7A 3S7BA 3M54A 4O6FA 5KJMA 3OS5A 2BQZA 3KMJA 1N6CA 1XQHA 5F6KC 3OXFA 4E47A 2JV0A 4LDGA 3S8PA 4NVQA 2W5YA 5TH7A 3CBMA 1PEGA 4QENA 4J7IA 5TTFA 5JJ0A 3MO2A 3PDNA 3CBPA 3TG5A 5ARGA 5JIYA 3MO5A 5EX3A 2IGQA 3KMTA 2W5ZA 3S7JA 5HQ8A 4J8OA 4MI0A 5EG2A 5F6LA 4YPAA 3DALA 5TEGA 1MUFA 4RZ0A 3RAYA 4J83A 3IHXA 4YNMA 3M55A 3QWPA 1ZKKA 3OOIA 3KMAA 4H12A 3RU0A 2F69A 4C1QA 3HNAA 5CPRB 4YNPA 4YPEA 3VUZA 5ARFA 3SWCA 5LSXA 2RFIA 4QEOA 3F9WA 5F5EA 5F59A 4FMUA 3OPEA 4IJ8A 4QEPA 4JLGA 3M59A 3K5KA 3M53A 3DB5A 4AU7A 3F9ZA 5KJNA 3RQ4A 3OXLA 5CCMA 5T0MA 1O9SA 3MEKA 3M58A 1N6AA 3BO5A 4YPUA 5T5GA 3SW9A 3M5AA 4J7FA 3M56A 3F9YA 5AYFA 1N3JA 4Z4PA 3EP0A 5T0KA 3FPDA 3QWVA 3S7DA 5JINA 2R3AA 4NJ5A 1ML9A 3VV0A 4JDSA 5KJLA 3N71A 4YNDA 4IJDA 5KJKA 3RIBA 3QWWA 5CCLA 3MO0A 1MT6A 4WUYA 3F9XA 3OXGA
chains in the Genus database with same CATH superfamily
4MI5A 1MVHA 2O8JA 4BUPA 1H3IA 2QPWA 3TG4A 4I51A 5EX0A 2G46A 3S7FA 3RJWA 4O30A 3CBOA 5LSZA 5JHNA 1MVXA 3M57A 5HI7A 3S7BA 3M54A 4O6FA 5KJMA 3OS5A 2BQZA 3KMJA 1N6CA 1XQHA 5F6KC 3OXFA 4E47A 2JV0A 4LDGA 3S8PA 4NVQA 2W5YA 5TH7A 3CBMA 1PEGA 4QENA 4J7IA 5TTFA 5JJ0A 3MO2A 3PDNA 3CBPA 3TG5A 5ARGA 5JIYA 3MO5A 5EX3A 2IGQA 3KMTA 2W5ZA 3S7JA 5HQ8A 4J8OA 4MI0A 5EG2A 5F6LA 4YPAA 3DALA 5TEGA 1MUFA 4RZ0A 3RAYA 4J83A 3IHXA 4YNMA 3M55A 3QWPA 1ZKKA 3OOIA 3KMAA 4H12A 3RU0A 2F69A 4C1QA 3HNAA 5CPRB 4YNPA 4YPEA 3VUZA 5ARFA 3SWCA 5LSXA 2RFIA 4QEOA 3F9WA 5F5EA 5F59A 4FMUA 3OPEA 4IJ8A 4QEPA 4JLGA 3M59A 3K5KA 3M53A 3DB5A 4AU7A 3F9ZA 5KJNA 3RQ4A 3OXLA 5CCMA 5T0MA 1O9SA 3MEKA 3M58A 1N6AA 3BO5A 4YPUA 5T5GA 3SW9A 3M5AA 4J7FA 3M56A 3F9YA 5AYFA 1N3JA 4Z4PA 3EP0A 5T0KA 3FPDA 3QWVA 3S7DA 5JINA 2R3AA 4NJ5A 1ML9A 3VV0A 4JDSA 5KJLA 3N71A 4YNDA 4IJDA 5KJKA 3RIBA 3QWWA 5CCLA 3MO0A 1MT6A 4WUYA 3F9XA 3OXGA
chains in the Genus database with same CATH topology
4MI5A 1MVHA 2O8JA 4BUPA 1H3IA 2QPWA 3TG4A 4I51A 5EX0A 2G46A 3S7FA 3RJWA 4O30A 3CBOA 5LSZA 5JHNA 1MVXA 3M57A 5HI7A 3S7BA 3M54A 4O6FA 5KJMA 3OS5A 2BQZA 3KMJA 1N6CA 1XQHA 5F6KC 3OXFA 4E47A 2JV0A 4LDGA 3S8PA 4NVQA 2W5YA 5TH7A 3CBMA 1PEGA 4QENA 4J7IA 5TTFA 5JJ0A 3MO2A 3PDNA 3CBPA 3TG5A 5ARGA 5JIYA 3MO5A 5EX3A 2IGQA 3KMTA 2W5ZA 3S7JA 5HQ8A 4J8OA 4MI0A 5EG2A 5F6LA 4YPAA 3DALA 5TEGA 1MUFA 4RZ0A 3RAYA 4J83A 3IHXA 4YNMA 3M55A 3QWPA 1ZKKA 3OOIA 3KMAA 4H12A 3RU0A 2F69A 4C1QA 3HNAA 5CPRB 4YNPA 4YPEA 3VUZA 5ARFA 3SWCA 5LSXA 2RFIA 4QEOA 3F9WA 5F5EA 5F59A 4FMUA 3OPEA 4IJ8A 4QEPA 4JLGA 3M59A 3K5KA 3M53A 3DB5A 4AU7A 3F9ZA 5KJNA 3RQ4A 3OXLA 5CCMA 5T0MA 1O9SA 3MEKA 3M58A 1N6AA 3BO5A 4YPUA 5T5GA 3SW9A 3M5AA 4J7FA 3M56A 3F9YA 5AYFA 1N3JA 4Z4PA 3EP0A 5T0KA 3FPDA 3QWVA 3S7DA 5JINA 2R3AA 4NJ5A 1ML9A 3VV0A 4JDSA 5KJLA 3N71A 4YNDA 4IJDA 5KJKA 3RIBA 3QWWA 5CCLA 3MO0A 1MT6A 4WUYA 3F9XA 3OXGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MI5 A;  1MVH A;  2O8J A;  4BUP A;  1H3I A;  2QPW A;  3TG4 A;  4I51 A;  5EX0 A;  2G46 A;  3S7F A;  3RJW A;  4O30 A;  3CBO A;  5LSZ A;  5JHN A;  1MVX A;  3M57 A;  5HI7 A;  3S7B A;  3M54 A;  4O6F A;  5KJM A;  3OS5 A;  2BQZ A;  3KMJ A;  1N6C A;  1XQH A;  5F6K C;  3OXF A;  4E47 A;  2JV0 A;  4LDG A;  3S8P A;  4NVQ A;  2W5Y A;  5TH7 A;  3CBM A;  1PEG A;  4QEN A;  4J7I A;  5TTF A;  5JJ0 A;  3MO2 A;  3PDN A;  3CBP A;  3TG5 A;  5ARG A;  5JIY A;  3MO5 A;  5EX3 A;  2IGQ A;  3KMT A;  2W5Z A;  3S7J A;  5HQ8 A;  4J8O A;  4MI0 A;  5EG2 A;  5F6L A;  4YPA A;  3DAL A;  5TEG A;  1MUF A;  4RZ0 A;  3RAY A;  4J83 A;  3IHX A;  4YNM A;  3M55 A;  3QWP A;  1ZKK A;  3OOI A;  3KMA A;  4H12 A;  3RU0 A;  2F69 A;  4C1Q A;  3HNA A;  5CPR B;  4YNP A;  4YPE A;  3VUZ A;  5ARF A;  3SWC A;  5LSX A;  2RFI A;  4QEO A;  3F9W A;  5F5E A;  5F59 A;  4FMU A;  3OPE A;  4IJ8 A;  4QEP A;  4JLG A;  3M59 A;  3K5K A;  3M53 A;  3DB5 A;  4AU7 A;  3F9Z A;  5KJN A;  3RQ4 A;  3OXL A;  5CCM A;  5T0M A;  1O9S A;  3MEK A;  3M58 A;  1N6A A;  3BO5 A;  4YPU A;  5T5G A;  3SW9 A;  3M5A A;  4J7F A;  3M56 A;  3F9Y A;  5AYF A;  1N3J A;  4Z4P A;  3EP0 A;  5T0K A;  3FPD A;  3QWV A;  3S7D A;  5JIN A;  2R3A A;  4NJ5 A;  1ML9 A;  3VV0 A;  4JDS A;  5KJL A;  3N71 A;  4YND A;  4IJD A;  5KJK A;  3RIB A;  3QWW A;  5CCL A;  3MO0 A;  1MT6 A;  4WUY A;  3F9X A;  3OXG A; 
#chains in the Genus database with same CATH topology
 4MI5 A;  1MVH A;  2O8J A;  4BUP A;  1H3I A;  2QPW A;  3TG4 A;  4I51 A;  5EX0 A;  2G46 A;  3S7F A;  3RJW A;  4O30 A;  3CBO A;  5LSZ A;  5JHN A;  1MVX A;  3M57 A;  5HI7 A;  3S7B A;  3M54 A;  4O6F A;  5KJM A;  3OS5 A;  2BQZ A;  3KMJ A;  1N6C A;  1XQH A;  5F6K C;  3OXF A;  4E47 A;  2JV0 A;  4LDG A;  3S8P A;  4NVQ A;  2W5Y A;  5TH7 A;  3CBM A;  1PEG A;  4QEN A;  4J7I A;  5TTF A;  5JJ0 A;  3MO2 A;  3PDN A;  3CBP A;  3TG5 A;  5ARG A;  5JIY A;  3MO5 A;  5EX3 A;  2IGQ A;  3KMT A;  2W5Z A;  3S7J A;  5HQ8 A;  4J8O A;  4MI0 A;  5EG2 A;  5F6L A;  4YPA A;  3DAL A;  5TEG A;  1MUF A;  4RZ0 A;  3RAY A;  4J83 A;  3IHX A;  4YNM A;  3M55 A;  3QWP A;  1ZKK A;  3OOI A;  3KMA A;  4H12 A;  3RU0 A;  2F69 A;  4C1Q A;  3HNA A;  5CPR B;  4YNP A;  4YPE A;  3VUZ A;  5ARF A;  3SWC A;  5LSX A;  2RFI A;  4QEO A;  3F9W A;  5F5E A;  5F59 A;  4FMU A;  3OPE A;  4IJ8 A;  4QEP A;  4JLG A;  3M59 A;  3K5K A;  3M53 A;  3DB5 A;  4AU7 A;  3F9Z A;  5KJN A;  3RQ4 A;  3OXL A;  5CCM A;  5T0M A;  1O9S A;  3MEK A;  3M58 A;  1N6A A;  3BO5 A;  4YPU A;  5T5G A;  3SW9 A;  3M5A A;  4J7F A;  3M56 A;  3F9Y A;  5AYF A;  1N3J A;  4Z4P A;  3EP0 A;  5T0K A;  3FPD A;  3QWV A;  3S7D A;  5JIN A;  2R3A A;  4NJ5 A;  1ML9 A;  3VV0 A;  4JDS A;  5KJL A;  3N71 A;  4YND A;  4IJD A;  5KJK A;  3RIB A;  3QWW A;  5CCL A;  3MO0 A;  1MT6 A;  4WUY A;  3F9X A;  3OXG A; 
#chains in the Genus database with same CATH homology
 4MI5 A;  1MVH A;  2O8J A;  4BUP A;  1H3I A;  2QPW A;  3TG4 A;  4I51 A;  5EX0 A;  2G46 A;  3S7F A;  3RJW A;  4O30 A;  3CBO A;  5LSZ A;  5JHN A;  1MVX A;  3M57 A;  5HI7 A;  3S7B A;  3M54 A;  4O6F A;  5KJM A;  3OS5 A;  2BQZ A;  3KMJ A;  1N6C A;  1XQH A;  5F6K C;  3OXF A;  4E47 A;  2JV0 A;  4LDG A;  3S8P A;  4NVQ A;  2W5Y A;  5TH7 A;  3CBM A;  1PEG A;  4QEN A;  4J7I A;  5TTF A;  5JJ0 A;  3MO2 A;  3PDN A;  3CBP A;  3TG5 A;  5ARG A;  5JIY A;  3MO5 A;  5EX3 A;  2IGQ A;  3KMT A;  2W5Z A;  3S7J A;  5HQ8 A;  4J8O A;  4MI0 A;  5EG2 A;  5F6L A;  4YPA A;  3DAL A;  5TEG A;  1MUF A;  4RZ0 A;  3RAY A;  4J83 A;  3IHX A;  4YNM A;  3M55 A;  3QWP A;  1ZKK A;  3OOI A;  3KMA A;  4H12 A;  3RU0 A;  2F69 A;  4C1Q A;  3HNA A;  5CPR B;  4YNP A;  4YPE A;  3VUZ A;  5ARF A;  3SWC A;  5LSX A;  2RFI A;  4QEO A;  3F9W A;  5F5E A;  5F59 A;  4FMU A;  3OPE A;  4IJ8 A;  4QEP A;  4JLG A;  3M59 A;  3K5K A;  3M53 A;  3DB5 A;  4AU7 A;  3F9Z A;  5KJN A;  3RQ4 A;  3OXL A;  5CCM A;  5T0M A;  1O9S A;  3MEK A;  3M58 A;  1N6A A;  3BO5 A;  4YPU A;  5T5G A;  3SW9 A;  3M5A A;  4J7F A;  3M56 A;  3F9Y A;  5AYF A;  1N3J A;  4Z4P A;  3EP0 A;  5T0K A;  3FPD A;  3QWV A;  3S7D A;  5JIN A;  2R3A A;  4NJ5 A;  1ML9 A;  3VV0 A;  4JDS A;  5KJL A;  3N71 A;  4YND A;  4IJD A;  5KJK A;  3RIB A;  3QWW A;  5CCL A;  3MO0 A;  1MT6 A;  4WUY A;  3F9X A;  3OXG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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