1H3IA

Crystal structure of the histone methyltransferase set7/9
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
293
structure length
293
Chain Sequence
FFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHSPPGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords HISTONE H3 LYSINE 4 SPECIFIC METHYLTRANSFERASE
publication title Crystal Structure and Functional Analysis of the Histone Methyltransferase Set7/9
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 71
structure length 293
sequence length 293
chains with identical sequence B
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-09-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF02493 MORN MORN repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.110.10 Mainly Beta Single Sheet Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 1h3iA01
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1h3iA02
1MVXA 5TEGA 5JJ0A 1MVHA 5JINA 3RAYA 2RFIA 2BQZA 2O8JA 4H12A 3OXFA 3F9YA 4NJ5A 1ZKKA 3RU0A 5EX0A 3RQ4A 3EP0A 1O9SA 4IJ8A 3M54A 4IJDA 3M58A 1ML9A 5T0MA 3OXGA 3IHXA 4YPUA 5CPRB 4BUPA 2W5YA 4O30A 3KMTA 3M55A 5KJLA 3MEKA 3QWWA 5KJNA 1N3JA 4C1QA 3MO0A 3TG5A 3S7BA 5KJMA 3DB5A 4YNPA 3RJWA 3OPEA 4I51A 5AYFA 4RZ0A 1XQHA 2QPWA 3S8PA 3S7DA 2IGQA 3KMJA 2R3AA 5T0KA 1MT6A 1H3IA 5F6KC 3M57A 5EX3A 2F69A 3DALA 5TTFA 4QEOA 3S7JA 5CCMA 3SW9A 4QEPA 4LDGA 3KMAA 5HQ8A 1PEGA 4J7IA 5LSZA 3RIBA 4NVQA 3S7FA 3QWPA 5CCLA 4FMUA 4JLGA 3FPDA 1MUFA 2G46A 5ARFA 4J8OA 5ARGA 4J7FA 4MI0A 3M5AA 3MO5A 4QENA 3OOIA 3PDNA 5LSXA 4AU7A 3TG4A 5T5GA 5F59A 5KJKA 5F6LA 5JHNA 2JV0A 4J83A 4E47A 4YPEA 3F9XA 3BO5A 4Z4PA 3CBPA 4YPAA 3K5KA 3OS5A 3OXLA 5HI7A 3HNAA 5EG2A 5JIYA 4JDSA 3CBOA 4WUYA 4YNDA 2W5ZA 4MI5A 1N6CA 1N6AA 3F9ZA 4YNMA 3M59A 5F5EA 3VV0A 3QWVA 3MO2A 3M56A 5TH7A 3CBMA 4O6FA 3VUZA 3N71A 3F9WA 3SWCA 3M53A
chains in the Genus database with same CATH superfamily
1MVXA 5TEGA 5JJ0A 1MVHA 5JINA 3RAYA 2RFIA 2BQZA 2O8JA 4H12A 3OXFA 3F9YA 4NJ5A 1ZKKA 3RU0A 5EX0A 3RQ4A 3EP0A 1O9SA 4IJ8A 3M54A 4IJDA 3M58A 1ML9A 5T0MA 3OXGA 3IHXA 4YPUA 5CPRB 4BUPA 2W5YA 4O30A 3KMTA 3M55A 5KJLA 3MEKA 3QWWA 5KJNA 1N3JA 4C1QA 3MO0A 3TG5A 3S7BA 5KJMA 3DB5A 4YNPA 3RJWA 3OPEA 4I51A 5AYFA 4RZ0A 1XQHA 2QPWA 3S8PA 3S7DA 2IGQA 3KMJA 2R3AA 5T0KA 1MT6A 1H3IA 5F6KC 3M57A 5EX3A 2F69A 3DALA 5TTFA 4QEOA 3S7JA 5CCMA 3SW9A 4QEPA 4LDGA 3KMAA 5HQ8A 1PEGA 4J7IA 5LSZA 3RIBA 4NVQA 3S7FA 3QWPA 5CCLA 4FMUA 4JLGA 3FPDA 1MUFA 2G46A 5ARFA 4J8OA 5ARGA 4J7FA 4MI0A 3M5AA 3MO5A 4QENA 3OOIA 3PDNA 5LSXA 4AU7A 3TG4A 5T5GA 5F59A 5KJKA 5F6LA 5JHNA 2JV0A 4J83A 4E47A 4YPEA 3F9XA 3BO5A 4Z4PA 3CBPA 4YPAA 3K5KA 3OS5A 3OXLA 5HI7A 3HNAA 5EG2A 5JIYA 4JDSA 3CBOA 4WUYA 4YNDA 2W5ZA 4MI5A 1N6CA 1N6AA 3F9ZA 4YNMA 3M59A 5F5EA 3VV0A 3QWVA 3MO2A 3M56A 5TH7A 3CBMA 4O6FA 3VUZA 3N71A 3F9WA 3SWCA 3M53A
chains in the Genus database with same CATH topology
1MVXA 5TEGA 5JJ0A 1MVHA 5JINA 3RAYA 2RFIA 2BQZA 2O8JA 4H12A 3OXFA 3F9YA 4NJ5A 1ZKKA 3RU0A 5EX0A 3RQ4A 3EP0A 1O9SA 4IJ8A 3M54A 4IJDA 3M58A 1ML9A 5T0MA 3OXGA 3IHXA 4YPUA 5CPRB 4BUPA 2W5YA 4O30A 3KMTA 3M55A 5KJLA 3MEKA 3QWWA 5KJNA 1N3JA 4C1QA 3MO0A 3TG5A 3S7BA 5KJMA 3DB5A 4YNPA 3RJWA 3OPEA 4I51A 5AYFA 4RZ0A 1XQHA 2QPWA 3S8PA 3S7DA 2IGQA 3KMJA 2R3AA 5T0KA 1MT6A 1H3IA 5F6KC 3M57A 5EX3A 2F69A 3DALA 5TTFA 4QEOA 3S7JA 5CCMA 3SW9A 4QEPA 4LDGA 3KMAA 5HQ8A 1PEGA 4J7IA 5LSZA 3RIBA 4NVQA 3S7FA 3QWPA 5CCLA 4FMUA 4JLGA 3FPDA 1MUFA 2G46A 5ARFA 4J8OA 5ARGA 4J7FA 4MI0A 3M5AA 3MO5A 4QENA 3OOIA 3PDNA 5LSXA 4AU7A 3TG4A 5T5GA 5F59A 5KJKA 5F6LA 5JHNA 2JV0A 4J83A 4E47A 4YPEA 3F9XA 3BO5A 4Z4PA 3CBPA 4YPAA 3K5KA 3OS5A 3OXLA 5HI7A 3HNAA 5EG2A 5JIYA 4JDSA 3CBOA 4WUYA 4YNDA 2W5ZA 4MI5A 1N6CA 1N6AA 3F9ZA 4YNMA 3M59A 5F5EA 3VV0A 3QWVA 3MO2A 3M56A 5TH7A 3CBMA 4O6FA 3VUZA 3N71A 3F9WA 3SWCA 3M53A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MVX A;  5TEG A;  5JJ0 A;  1MVH A;  5JIN A;  3RAY A;  2RFI A;  2BQZ A;  2O8J A;  4H12 A;  3OXF A;  3F9Y A;  4NJ5 A;  1ZKK A;  3RU0 A;  5EX0 A;  3RQ4 A;  3EP0 A;  1O9S A;  4IJ8 A;  3M54 A;  4IJD A;  3M58 A;  1ML9 A;  5T0M A;  3OXG A;  3IHX A;  4YPU A;  5CPR B;  4BUP A;  2W5Y A;  4O30 A;  3KMT A;  3M55 A;  5KJL A;  3MEK A;  3QWW A;  5KJN A;  1N3J A;  4C1Q A;  3MO0 A;  3TG5 A;  3S7B A;  5KJM A;  3DB5 A;  4YNP A;  3RJW A;  3OPE A;  4I51 A;  5AYF A;  4RZ0 A;  1XQH A;  2QPW A;  3S8P A;  3S7D A;  2IGQ A;  3KMJ A;  2R3A A;  5T0K A;  1MT6 A;  1H3I A;  5F6K C;  3M57 A;  5EX3 A;  2F69 A;  3DAL A;  5TTF A;  4QEO A;  3S7J A;  5CCM A;  3SW9 A;  4QEP A;  4LDG A;  3KMA A;  5HQ8 A;  1PEG A;  4J7I A;  5LSZ A;  3RIB A;  4NVQ A;  3S7F A;  3QWP A;  5CCL A;  4FMU A;  4JLG A;  3FPD A;  1MUF A;  2G46 A;  5ARF A;  4J8O A;  5ARG A;  4J7F A;  4MI0 A;  3M5A A;  3MO5 A;  4QEN A;  3OOI A;  3PDN A;  5LSX A;  4AU7 A;  3TG4 A;  5T5G A;  5F59 A;  5KJK A;  5F6L A;  5JHN A;  2JV0 A;  4J83 A;  4E47 A;  4YPE A;  3F9X A;  3BO5 A;  4Z4P A;  3CBP A;  4YPA A;  3K5K A;  3OS5 A;  3OXL A;  5HI7 A;  3HNA A;  5EG2 A;  5JIY A;  4JDS A;  3CBO A;  4WUY A;  4YND A;  2W5Z A;  4MI5 A;  1N6C A;  1N6A A;  3F9Z A;  4YNM A;  3M59 A;  5F5E A;  3VV0 A;  3QWV A;  3MO2 A;  3M56 A;  5TH7 A;  3CBM A;  4O6F A;  3VUZ A;  3N71 A;  3F9W A;  3SWC A;  3M53 A; 
#chains in the Genus database with same CATH topology
 1MVX A;  5TEG A;  5JJ0 A;  1MVH A;  5JIN A;  3RAY A;  2RFI A;  2BQZ A;  2O8J A;  4H12 A;  3OXF A;  3F9Y A;  4NJ5 A;  1ZKK A;  3RU0 A;  5EX0 A;  3RQ4 A;  3EP0 A;  1O9S A;  4IJ8 A;  3M54 A;  4IJD A;  3M58 A;  1ML9 A;  5T0M A;  3OXG A;  3IHX A;  4YPU A;  5CPR B;  4BUP A;  2W5Y A;  4O30 A;  3KMT A;  3M55 A;  5KJL A;  3MEK A;  3QWW A;  5KJN A;  1N3J A;  4C1Q A;  3MO0 A;  3TG5 A;  3S7B A;  5KJM A;  3DB5 A;  4YNP A;  3RJW A;  3OPE A;  4I51 A;  5AYF A;  4RZ0 A;  1XQH A;  2QPW A;  3S8P A;  3S7D A;  2IGQ A;  3KMJ A;  2R3A A;  5T0K A;  1MT6 A;  1H3I A;  5F6K C;  3M57 A;  5EX3 A;  2F69 A;  3DAL A;  5TTF A;  4QEO A;  3S7J A;  5CCM A;  3SW9 A;  4QEP A;  4LDG A;  3KMA A;  5HQ8 A;  1PEG A;  4J7I A;  5LSZ A;  3RIB A;  4NVQ A;  3S7F A;  3QWP A;  5CCL A;  4FMU A;  4JLG A;  3FPD A;  1MUF A;  2G46 A;  5ARF A;  4J8O A;  5ARG A;  4J7F A;  4MI0 A;  3M5A A;  3MO5 A;  4QEN A;  3OOI A;  3PDN A;  5LSX A;  4AU7 A;  3TG4 A;  5T5G A;  5F59 A;  5KJK A;  5F6L A;  5JHN A;  2JV0 A;  4J83 A;  4E47 A;  4YPE A;  3F9X A;  3BO5 A;  4Z4P A;  3CBP A;  4YPA A;  3K5K A;  3OS5 A;  3OXL A;  5HI7 A;  3HNA A;  5EG2 A;  5JIY A;  4JDS A;  3CBO A;  4WUY A;  4YND A;  2W5Z A;  4MI5 A;  1N6C A;  1N6A A;  3F9Z A;  4YNM A;  3M59 A;  5F5E A;  3VV0 A;  3QWV A;  3MO2 A;  3M56 A;  5TH7 A;  3CBM A;  4O6F A;  3VUZ A;  3N71 A;  3F9W A;  3SWC A;  3M53 A; 
#chains in the Genus database with same CATH homology
 1MVX A;  5TEG A;  5JJ0 A;  1MVH A;  5JIN A;  3RAY A;  2RFI A;  2BQZ A;  2O8J A;  4H12 A;  3OXF A;  3F9Y A;  4NJ5 A;  1ZKK A;  3RU0 A;  5EX0 A;  3RQ4 A;  3EP0 A;  1O9S A;  4IJ8 A;  3M54 A;  4IJD A;  3M58 A;  1ML9 A;  5T0M A;  3OXG A;  3IHX A;  4YPU A;  5CPR B;  4BUP A;  2W5Y A;  4O30 A;  3KMT A;  3M55 A;  5KJL A;  3MEK A;  3QWW A;  5KJN A;  1N3J A;  4C1Q A;  3MO0 A;  3TG5 A;  3S7B A;  5KJM A;  3DB5 A;  4YNP A;  3RJW A;  3OPE A;  4I51 A;  5AYF A;  4RZ0 A;  1XQH A;  2QPW A;  3S8P A;  3S7D A;  2IGQ A;  3KMJ A;  2R3A A;  5T0K A;  1MT6 A;  1H3I A;  5F6K C;  3M57 A;  5EX3 A;  2F69 A;  3DAL A;  5TTF A;  4QEO A;  3S7J A;  5CCM A;  3SW9 A;  4QEP A;  4LDG A;  3KMA A;  5HQ8 A;  1PEG A;  4J7I A;  5LSZ A;  3RIB A;  4NVQ A;  3S7F A;  3QWP A;  5CCL A;  4FMU A;  4JLG A;  3FPD A;  1MUF A;  2G46 A;  5ARF A;  4J8O A;  5ARG A;  4J7F A;  4MI0 A;  3M5A A;  3MO5 A;  4QEN A;  3OOI A;  3PDN A;  5LSX A;  4AU7 A;  3TG4 A;  5T5G A;  5F59 A;  5KJK A;  5F6L A;  5JHN A;  2JV0 A;  4J83 A;  4E47 A;  4YPE A;  3F9X A;  3BO5 A;  4Z4P A;  3CBP A;  4YPA A;  3K5K A;  3OS5 A;  3OXL A;  5HI7 A;  3HNA A;  5EG2 A;  5JIY A;  4JDS A;  3CBO A;  4WUY A;  4YND A;  2W5Z A;  4MI5 A;  1N6C A;  1N6A A;  3F9Z A;  4YNM A;  3M59 A;  5F5E A;  3VV0 A;  3QWV A;  3MO2 A;  3M56 A;  5TH7 A;  3CBM A;  4O6F A;  3VUZ A;  3N71 A;  3F9W A;  3SWC A;  3M53 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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