1H3IA

Crystal structure of the histone methyltransferase set7/9
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
293
structure length
293
Chain Sequence
FFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHSPPGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure and Functional Analysis of the Histone Methyltransferase Set7/9
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
molecule keywords HISTONE H3 LYSINE 4 SPECIFIC METHYLTRANSFERASE
total genus 71
structure length 293
sequence length 293
chains with identical sequence B
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-09-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF02493 MORN MORN repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.110.10 Mainly Beta Single Sheet Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 1h3iA01
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1h3iA02
5ARFA 4YPAA 4NVQA 5EX3A 3BO5A 5JINA 3OXLA 1N3JA 5T0KA 5CPRB 3M55A 5F6KC 5ARGA 5AYFA 3RU0A 2G46A 5CCMA 3OXGA 1MVXA 1O9SA 3VUZA 3S7BA 3RIBA 3DALA 4WUYA 3VV0A 2QPWA 1MT6A 3OPEA 5JIYA 4J8OA 5CCLA 3F9WA 4AU7A 4IJDA 3TG4A 4QENA 3QWVA 3S7FA 5LSZA 4LDGA 2JV0A 4C1QA 3M5AA 2F69A 4YPEA 4QEOA 1ML9A 3F9ZA 5HI7A 4QEPA 4MI5A 5T0MA 3SWCA 4J83A 4RZ0A 4O30A 3F9YA 5EX0A 3M53A 3CBOA 3IHXA 4J7IA 3RQ4A 5LSXA 2IGQA 3M54A 4JLGA 5JJ0A 3HNAA 5F59A 5KJMA 4H12A 3KMAA 1MVHA 4NJ5A 3OS5A 5F5EA 1PEGA 5T5GA 3MO2A 5F6LA 5KJLA 4I51A 4YNDA 5EG2A 3F9XA 3CBPA 3M57A 5KJKA 2RFIA 3OXFA 4IJ8A 4Z4PA 3N71A 1ZKKA 3PDNA 3QWWA 3S8PA 5TH7A 1MUFA 1N6AA 3FPDA 4J7FA 3KMJA 4YNPA 3CBMA 3RJWA 5KJNA 3KMTA 4YPUA 3TG5A 3K5KA 3M59A 1N6CA 5TEGA 2O8JA 3MEKA 2BQZA 4YNMA 3MO0A 3M58A 3S7JA 3MO5A 5HQ8A 5JHNA 3QWPA 3OOIA 1XQHA 4JDSA 3RAYA 3S7DA 4FMUA 5TTFA 2W5YA 1H3IA 3DB5A 3M56A 2R3AA 2W5ZA 4BUPA 3SW9A 3EP0A 4E47A 4MI0A 4O6FA
chains in the Genus database with same CATH superfamily
5ARFA 4YPAA 4NVQA 5EX3A 3BO5A 5JINA 3OXLA 1N3JA 5T0KA 5CPRB 3M55A 5F6KC 5ARGA 5AYFA 3RU0A 2G46A 5CCMA 3OXGA 1MVXA 1O9SA 3VUZA 3S7BA 3RIBA 3DALA 4WUYA 3VV0A 2QPWA 1MT6A 3OPEA 5JIYA 4J8OA 5CCLA 3F9WA 4AU7A 4IJDA 3TG4A 4QENA 3QWVA 3S7FA 5LSZA 4LDGA 2JV0A 4C1QA 3M5AA 2F69A 4YPEA 4QEOA 1ML9A 3F9ZA 5HI7A 4QEPA 4MI5A 5T0MA 3SWCA 4J83A 4RZ0A 4O30A 3F9YA 5EX0A 3M53A 3CBOA 3IHXA 4J7IA 3RQ4A 5LSXA 2IGQA 3M54A 4JLGA 5JJ0A 3HNAA 5F59A 5KJMA 4H12A 3KMAA 1MVHA 4NJ5A 3OS5A 5F5EA 1PEGA 5T5GA 3MO2A 5F6LA 5KJLA 4I51A 4YNDA 5EG2A 3F9XA 3CBPA 3M57A 5KJKA 2RFIA 3OXFA 4IJ8A 4Z4PA 3N71A 1ZKKA 3PDNA 3QWWA 3S8PA 5TH7A 1MUFA 1N6AA 3FPDA 4J7FA 3KMJA 4YNPA 3CBMA 3RJWA 5KJNA 3KMTA 4YPUA 3TG5A 3K5KA 3M59A 1N6CA 5TEGA 2O8JA 3MEKA 2BQZA 4YNMA 3MO0A 3M58A 3S7JA 3MO5A 5HQ8A 5JHNA 3QWPA 3OOIA 1XQHA 4JDSA 3RAYA 3S7DA 4FMUA 5TTFA 2W5YA 1H3IA 3DB5A 3M56A 2R3AA 2W5ZA 4BUPA 3SW9A 3EP0A 4E47A 4MI0A 4O6FA
chains in the Genus database with same CATH topology
5ARFA 4YPAA 4NVQA 5EX3A 3BO5A 5JINA 3OXLA 1N3JA 5T0KA 5CPRB 3M55A 5F6KC 5ARGA 5AYFA 3RU0A 2G46A 5CCMA 3OXGA 1MVXA 1O9SA 3VUZA 3S7BA 3RIBA 3DALA 4WUYA 3VV0A 2QPWA 1MT6A 3OPEA 5JIYA 4J8OA 5CCLA 3F9WA 4AU7A 4IJDA 3TG4A 4QENA 3QWVA 3S7FA 5LSZA 4LDGA 2JV0A 4C1QA 3M5AA 2F69A 4YPEA 4QEOA 1ML9A 3F9ZA 5HI7A 4QEPA 4MI5A 5T0MA 3SWCA 4J83A 4RZ0A 4O30A 3F9YA 5EX0A 3M53A 3CBOA 3IHXA 4J7IA 3RQ4A 5LSXA 2IGQA 3M54A 4JLGA 5JJ0A 3HNAA 5F59A 5KJMA 4H12A 3KMAA 1MVHA 4NJ5A 3OS5A 5F5EA 1PEGA 5T5GA 3MO2A 5F6LA 5KJLA 4I51A 4YNDA 5EG2A 3F9XA 3CBPA 3M57A 5KJKA 2RFIA 3OXFA 4IJ8A 4Z4PA 3N71A 1ZKKA 3PDNA 3QWWA 3S8PA 5TH7A 1MUFA 1N6AA 3FPDA 4J7FA 3KMJA 4YNPA 3CBMA 3RJWA 5KJNA 3KMTA 4YPUA 3TG5A 3K5KA 3M59A 1N6CA 5TEGA 2O8JA 3MEKA 2BQZA 4YNMA 3MO0A 3M58A 3S7JA 3MO5A 5HQ8A 5JHNA 3QWPA 3OOIA 1XQHA 4JDSA 3RAYA 3S7DA 4FMUA 5TTFA 2W5YA 1H3IA 3DB5A 3M56A 2R3AA 2W5ZA 4BUPA 3SW9A 3EP0A 4E47A 4MI0A 4O6FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ARF A;  4YPA A;  4NVQ A;  5EX3 A;  3BO5 A;  5JIN A;  3OXL A;  1N3J A;  5T0K A;  5CPR B;  3M55 A;  5F6K C;  5ARG A;  5AYF A;  3RU0 A;  2G46 A;  5CCM A;  3OXG A;  1MVX A;  1O9S A;  3VUZ A;  3S7B A;  3RIB A;  3DAL A;  4WUY A;  3VV0 A;  2QPW A;  1MT6 A;  3OPE A;  5JIY A;  4J8O A;  5CCL A;  3F9W A;  4AU7 A;  4IJD A;  3TG4 A;  4QEN A;  3QWV A;  3S7F A;  5LSZ A;  4LDG A;  2JV0 A;  4C1Q A;  3M5A A;  2F69 A;  4YPE A;  4QEO A;  1ML9 A;  3F9Z A;  5HI7 A;  4QEP A;  4MI5 A;  5T0M A;  3SWC A;  4J83 A;  4RZ0 A;  4O30 A;  3F9Y A;  5EX0 A;  3M53 A;  3CBO A;  3IHX A;  4J7I A;  3RQ4 A;  5LSX A;  2IGQ A;  3M54 A;  4JLG A;  5JJ0 A;  3HNA A;  5F59 A;  5KJM A;  4H12 A;  3KMA A;  1MVH A;  4NJ5 A;  3OS5 A;  5F5E A;  1PEG A;  5T5G A;  3MO2 A;  5F6L A;  5KJL A;  4I51 A;  4YND A;  5EG2 A;  3F9X A;  3CBP A;  3M57 A;  5KJK A;  2RFI A;  3OXF A;  4IJ8 A;  4Z4P A;  3N71 A;  1ZKK A;  3PDN A;  3QWW A;  3S8P A;  5TH7 A;  1MUF A;  1N6A A;  3FPD A;  4J7F A;  3KMJ A;  4YNP A;  3CBM A;  3RJW A;  5KJN A;  3KMT A;  4YPU A;  3TG5 A;  3K5K A;  3M59 A;  1N6C A;  5TEG A;  2O8J A;  3MEK A;  2BQZ A;  4YNM A;  3MO0 A;  3M58 A;  3S7J A;  3MO5 A;  5HQ8 A;  5JHN A;  3QWP A;  3OOI A;  1XQH A;  4JDS A;  3RAY A;  3S7D A;  4FMU A;  5TTF A;  2W5Y A;  1H3I A;  3DB5 A;  3M56 A;  2R3A A;  2W5Z A;  4BUP A;  3SW9 A;  3EP0 A;  4E47 A;  4MI0 A;  4O6F A; 
#chains in the Genus database with same CATH topology
 5ARF A;  4YPA A;  4NVQ A;  5EX3 A;  3BO5 A;  5JIN A;  3OXL A;  1N3J A;  5T0K A;  5CPR B;  3M55 A;  5F6K C;  5ARG A;  5AYF A;  3RU0 A;  2G46 A;  5CCM A;  3OXG A;  1MVX A;  1O9S A;  3VUZ A;  3S7B A;  3RIB A;  3DAL A;  4WUY A;  3VV0 A;  2QPW A;  1MT6 A;  3OPE A;  5JIY A;  4J8O A;  5CCL A;  3F9W A;  4AU7 A;  4IJD A;  3TG4 A;  4QEN A;  3QWV A;  3S7F A;  5LSZ A;  4LDG A;  2JV0 A;  4C1Q A;  3M5A A;  2F69 A;  4YPE A;  4QEO A;  1ML9 A;  3F9Z A;  5HI7 A;  4QEP A;  4MI5 A;  5T0M A;  3SWC A;  4J83 A;  4RZ0 A;  4O30 A;  3F9Y A;  5EX0 A;  3M53 A;  3CBO A;  3IHX A;  4J7I A;  3RQ4 A;  5LSX A;  2IGQ A;  3M54 A;  4JLG A;  5JJ0 A;  3HNA A;  5F59 A;  5KJM A;  4H12 A;  3KMA A;  1MVH A;  4NJ5 A;  3OS5 A;  5F5E A;  1PEG A;  5T5G A;  3MO2 A;  5F6L A;  5KJL A;  4I51 A;  4YND A;  5EG2 A;  3F9X A;  3CBP A;  3M57 A;  5KJK A;  2RFI A;  3OXF A;  4IJ8 A;  4Z4P A;  3N71 A;  1ZKK A;  3PDN A;  3QWW A;  3S8P A;  5TH7 A;  1MUF A;  1N6A A;  3FPD A;  4J7F A;  3KMJ A;  4YNP A;  3CBM A;  3RJW A;  5KJN A;  3KMT A;  4YPU A;  3TG5 A;  3K5K A;  3M59 A;  1N6C A;  5TEG A;  2O8J A;  3MEK A;  2BQZ A;  4YNM A;  3MO0 A;  3M58 A;  3S7J A;  3MO5 A;  5HQ8 A;  5JHN A;  3QWP A;  3OOI A;  1XQH A;  4JDS A;  3RAY A;  3S7D A;  4FMU A;  5TTF A;  2W5Y A;  1H3I A;  3DB5 A;  3M56 A;  2R3A A;  2W5Z A;  4BUP A;  3SW9 A;  3EP0 A;  4E47 A;  4MI0 A;  4O6F A; 
#chains in the Genus database with same CATH homology
 5ARF A;  4YPA A;  4NVQ A;  5EX3 A;  3BO5 A;  5JIN A;  3OXL A;  1N3J A;  5T0K A;  5CPR B;  3M55 A;  5F6K C;  5ARG A;  5AYF A;  3RU0 A;  2G46 A;  5CCM A;  3OXG A;  1MVX A;  1O9S A;  3VUZ A;  3S7B A;  3RIB A;  3DAL A;  4WUY A;  3VV0 A;  2QPW A;  1MT6 A;  3OPE A;  5JIY A;  4J8O A;  5CCL A;  3F9W A;  4AU7 A;  4IJD A;  3TG4 A;  4QEN A;  3QWV A;  3S7F A;  5LSZ A;  4LDG A;  2JV0 A;  4C1Q A;  3M5A A;  2F69 A;  4YPE A;  4QEO A;  1ML9 A;  3F9Z A;  5HI7 A;  4QEP A;  4MI5 A;  5T0M A;  3SWC A;  4J83 A;  4RZ0 A;  4O30 A;  3F9Y A;  5EX0 A;  3M53 A;  3CBO A;  3IHX A;  4J7I A;  3RQ4 A;  5LSX A;  2IGQ A;  3M54 A;  4JLG A;  5JJ0 A;  3HNA A;  5F59 A;  5KJM A;  4H12 A;  3KMA A;  1MVH A;  4NJ5 A;  3OS5 A;  5F5E A;  1PEG A;  5T5G A;  3MO2 A;  5F6L A;  5KJL A;  4I51 A;  4YND A;  5EG2 A;  3F9X A;  3CBP A;  3M57 A;  5KJK A;  2RFI A;  3OXF A;  4IJ8 A;  4Z4P A;  3N71 A;  1ZKK A;  3PDN A;  3QWW A;  3S8P A;  5TH7 A;  1MUF A;  1N6A A;  3FPD A;  4J7F A;  3KMJ A;  4YNP A;  3CBM A;  3RJW A;  5KJN A;  3KMT A;  4YPU A;  3TG5 A;  3K5K A;  3M59 A;  1N6C A;  5TEG A;  2O8J A;  3MEK A;  2BQZ A;  4YNM A;  3MO0 A;  3M58 A;  3S7J A;  3MO5 A;  5HQ8 A;  5JHN A;  3QWP A;  3OOI A;  1XQH A;  4JDS A;  3RAY A;  3S7D A;  4FMU A;  5TTF A;  2W5Y A;  1H3I A;  3DB5 A;  3M56 A;  2R3A A;  2W5Z A;  4BUP A;  3SW9 A;  3EP0 A;  4E47 A;  4MI0 A;  4O6F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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