3SWCA

Glp (g9a-like protein) set domain in complex with dnmt3ak44me2 peptide
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
261
structure length
261
Chain Sequence
VERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDCSSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELISDSEADVREEDSYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYGERFWDIKGKLFSCRCGSPKCRHS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords Histone-lysine N-methyltransferase EHMT1
publication title MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
pubmed doi rcsb
source organism Homo sapiens
total genus 69
structure length 261
sequence length 261
chains with identical sequence B
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2011-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 3swcA00
3KMJA 4BUPA 3S7DA 5ARFA 4I51A 5JINA 3K5KA 3RQ4A 4QENA 4QEPA 4YNDA 4AU7A 4QEOA 3S7FA 3DALA 3OPEA 2RFIA 4WUYA 3CBMA 3CBPA 4MI0A 5JJ0A 1H3IA 5EG2A 3EP0A 4RZ0A 3HNAA 5CCMA 3S7BA 1O9SA 2IGQA 4MI5A 3BO5A 3M57A 3F9YA 3M55A 3QWVA 3QWWA 5HQ8A 1ZKKA 3MO5A 5KJLA 4YPUA 3OXLA 3M54A 3RU0A 3RJWA 5T0MA 3IHXA 5T0KA 4C1QA 3M5AA 3OS5A 3VV0A 3RAYA 5JIYA 3SW9A 5TTFA 4E47A 5EX3A 5JHNA 3F9ZA 1MUFA 4J8OA 5KJMA 3F9XA 1N6CA 4FMUA 2R3AA 4JDSA 3S8PA 2O8JA 4YPAA 4NVQA 3QWPA 3MO0A 3M59A 3MEKA 4J7FA 5F59A 3CBOA 1MVXA 4JLGA 5CCLA 5TH7A 5AYFA 3KMAA 4IJDA 3S7JA 3M56A 5F6KC 5ARGA 3MO2A 2F69A 4LDGA 3KMTA 1ML9A 3RIBA 1MVHA 5T5GA 5HI7A 3DB5A 2JV0A 1MT6A 3VUZA 4J83A 1XQHA 3M53A 4O30A 3F9WA 1PEGA 3PDNA 3N71A 4NJ5A 4YNMA 3SWCA 5KJNA 3FPDA 5F6LA 1N6AA 2W5YA 3M58A 4H12A 3OXGA 3OOIA 2W5ZA 4IJ8A 1N3JA 3OXFA 4Z4PA 3TG5A 4O6FA 5LSXA 5TEGA 5EX0A 5CPRB 5F5EA 4YPEA 2BQZA 4J7IA 5LSZA 4YNPA 3TG4A 5KJKA 2G46A 2QPWA
chains in the Genus database with same CATH superfamily
3KMJA 4BUPA 3S7DA 5ARFA 4I51A 5JINA 3K5KA 3RQ4A 4QENA 4QEPA 4YNDA 4AU7A 4QEOA 3S7FA 3DALA 3OPEA 2RFIA 4WUYA 3CBMA 3CBPA 4MI0A 5JJ0A 1H3IA 5EG2A 3EP0A 4RZ0A 3HNAA 5CCMA 3S7BA 1O9SA 2IGQA 4MI5A 3BO5A 3M57A 3F9YA 3M55A 3QWVA 3QWWA 5HQ8A 1ZKKA 3MO5A 5KJLA 4YPUA 3OXLA 3M54A 3RU0A 3RJWA 5T0MA 3IHXA 5T0KA 4C1QA 3M5AA 3OS5A 3VV0A 3RAYA 5JIYA 3SW9A 5TTFA 4E47A 5EX3A 5JHNA 3F9ZA 1MUFA 4J8OA 5KJMA 3F9XA 1N6CA 4FMUA 2R3AA 4JDSA 3S8PA 2O8JA 4YPAA 4NVQA 3QWPA 3MO0A 3M59A 3MEKA 4J7FA 5F59A 3CBOA 1MVXA 4JLGA 5CCLA 5TH7A 5AYFA 3KMAA 4IJDA 3S7JA 3M56A 5F6KC 5ARGA 3MO2A 2F69A 4LDGA 3KMTA 1ML9A 3RIBA 1MVHA 5T5GA 5HI7A 3DB5A 2JV0A 1MT6A 3VUZA 4J83A 1XQHA 3M53A 4O30A 3F9WA 1PEGA 3PDNA 3N71A 4NJ5A 4YNMA 3SWCA 5KJNA 3FPDA 5F6LA 1N6AA 2W5YA 3M58A 4H12A 3OXGA 3OOIA 2W5ZA 4IJ8A 1N3JA 3OXFA 4Z4PA 3TG5A 4O6FA 5LSXA 5TEGA 5EX0A 5CPRB 5F5EA 4YPEA 2BQZA 4J7IA 5LSZA 4YNPA 3TG4A 5KJKA 2G46A 2QPWA
chains in the Genus database with same CATH topology
3KMJA 4BUPA 3S7DA 5ARFA 4I51A 5JINA 3K5KA 3RQ4A 4QENA 4QEPA 4YNDA 4AU7A 4QEOA 3S7FA 3DALA 3OPEA 2RFIA 4WUYA 3CBMA 3CBPA 4MI0A 5JJ0A 1H3IA 5EG2A 3EP0A 4RZ0A 3HNAA 5CCMA 3S7BA 1O9SA 2IGQA 4MI5A 3BO5A 3M57A 3F9YA 3M55A 3QWVA 3QWWA 5HQ8A 1ZKKA 3MO5A 5KJLA 4YPUA 3OXLA 3M54A 3RU0A 3RJWA 5T0MA 3IHXA 5T0KA 4C1QA 3M5AA 3OS5A 3VV0A 3RAYA 5JIYA 3SW9A 5TTFA 4E47A 5EX3A 5JHNA 3F9ZA 1MUFA 4J8OA 5KJMA 3F9XA 1N6CA 4FMUA 2R3AA 4JDSA 3S8PA 2O8JA 4YPAA 4NVQA 3QWPA 3MO0A 3M59A 3MEKA 4J7FA 5F59A 3CBOA 1MVXA 4JLGA 5CCLA 5TH7A 5AYFA 3KMAA 4IJDA 3S7JA 3M56A 5F6KC 5ARGA 3MO2A 2F69A 4LDGA 3KMTA 1ML9A 3RIBA 1MVHA 5T5GA 5HI7A 3DB5A 2JV0A 1MT6A 3VUZA 4J83A 1XQHA 3M53A 4O30A 3F9WA 1PEGA 3PDNA 3N71A 4NJ5A 4YNMA 3SWCA 5KJNA 3FPDA 5F6LA 1N6AA 2W5YA 3M58A 4H12A 3OXGA 3OOIA 2W5ZA 4IJ8A 1N3JA 3OXFA 4Z4PA 3TG5A 4O6FA 5LSXA 5TEGA 5EX0A 5CPRB 5F5EA 4YPEA 2BQZA 4J7IA 5LSZA 4YNPA 3TG4A 5KJKA 2G46A 2QPWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KMJ A;  4BUP A;  3S7D A;  5ARF A;  4I51 A;  5JIN A;  3K5K A;  3RQ4 A;  4QEN A;  4QEP A;  4YND A;  4AU7 A;  4QEO A;  3S7F A;  3DAL A;  3OPE A;  2RFI A;  4WUY A;  3CBM A;  3CBP A;  4MI0 A;  5JJ0 A;  1H3I A;  5EG2 A;  3EP0 A;  4RZ0 A;  3HNA A;  5CCM A;  3S7B A;  1O9S A;  2IGQ A;  4MI5 A;  3BO5 A;  3M57 A;  3F9Y A;  3M55 A;  3QWV A;  3QWW A;  5HQ8 A;  1ZKK A;  3MO5 A;  5KJL A;  4YPU A;  3OXL A;  3M54 A;  3RU0 A;  3RJW A;  5T0M A;  3IHX A;  5T0K A;  4C1Q A;  3M5A A;  3OS5 A;  3VV0 A;  3RAY A;  5JIY A;  3SW9 A;  5TTF A;  4E47 A;  5EX3 A;  5JHN A;  3F9Z A;  1MUF A;  4J8O A;  5KJM A;  3F9X A;  1N6C A;  4FMU A;  2R3A A;  4JDS A;  3S8P A;  2O8J A;  4YPA A;  4NVQ A;  3QWP A;  3MO0 A;  3M59 A;  3MEK A;  4J7F A;  5F59 A;  3CBO A;  1MVX A;  4JLG A;  5CCL A;  5TH7 A;  5AYF A;  3KMA A;  4IJD A;  3S7J A;  3M56 A;  5F6K C;  5ARG A;  3MO2 A;  2F69 A;  4LDG A;  3KMT A;  1ML9 A;  3RIB A;  1MVH A;  5T5G A;  5HI7 A;  3DB5 A;  2JV0 A;  1MT6 A;  3VUZ A;  4J83 A;  1XQH A;  3M53 A;  4O30 A;  3F9W A;  1PEG A;  3PDN A;  3N71 A;  4NJ5 A;  4YNM A;  3SWC A;  5KJN A;  3FPD A;  5F6L A;  1N6A A;  2W5Y A;  3M58 A;  4H12 A;  3OXG A;  3OOI A;  2W5Z A;  4IJ8 A;  1N3J A;  3OXF A;  4Z4P A;  3TG5 A;  4O6F A;  5LSX A;  5TEG A;  5EX0 A;  5CPR B;  5F5E A;  4YPE A;  2BQZ A;  4J7I A;  5LSZ A;  4YNP A;  3TG4 A;  5KJK A;  2G46 A;  2QPW A; 
#chains in the Genus database with same CATH topology
 3KMJ A;  4BUP A;  3S7D A;  5ARF A;  4I51 A;  5JIN A;  3K5K A;  3RQ4 A;  4QEN A;  4QEP A;  4YND A;  4AU7 A;  4QEO A;  3S7F A;  3DAL A;  3OPE A;  2RFI A;  4WUY A;  3CBM A;  3CBP A;  4MI0 A;  5JJ0 A;  1H3I A;  5EG2 A;  3EP0 A;  4RZ0 A;  3HNA A;  5CCM A;  3S7B A;  1O9S A;  2IGQ A;  4MI5 A;  3BO5 A;  3M57 A;  3F9Y A;  3M55 A;  3QWV A;  3QWW A;  5HQ8 A;  1ZKK A;  3MO5 A;  5KJL A;  4YPU A;  3OXL A;  3M54 A;  3RU0 A;  3RJW A;  5T0M A;  3IHX A;  5T0K A;  4C1Q A;  3M5A A;  3OS5 A;  3VV0 A;  3RAY A;  5JIY A;  3SW9 A;  5TTF A;  4E47 A;  5EX3 A;  5JHN A;  3F9Z A;  1MUF A;  4J8O A;  5KJM A;  3F9X A;  1N6C A;  4FMU A;  2R3A A;  4JDS A;  3S8P A;  2O8J A;  4YPA A;  4NVQ A;  3QWP A;  3MO0 A;  3M59 A;  3MEK A;  4J7F A;  5F59 A;  3CBO A;  1MVX A;  4JLG A;  5CCL A;  5TH7 A;  5AYF A;  3KMA A;  4IJD A;  3S7J A;  3M56 A;  5F6K C;  5ARG A;  3MO2 A;  2F69 A;  4LDG A;  3KMT A;  1ML9 A;  3RIB A;  1MVH A;  5T5G A;  5HI7 A;  3DB5 A;  2JV0 A;  1MT6 A;  3VUZ A;  4J83 A;  1XQH A;  3M53 A;  4O30 A;  3F9W A;  1PEG A;  3PDN A;  3N71 A;  4NJ5 A;  4YNM A;  3SWC A;  5KJN A;  3FPD A;  5F6L A;  1N6A A;  2W5Y A;  3M58 A;  4H12 A;  3OXG A;  3OOI A;  2W5Z A;  4IJ8 A;  1N3J A;  3OXF A;  4Z4P A;  3TG5 A;  4O6F A;  5LSX A;  5TEG A;  5EX0 A;  5CPR B;  5F5E A;  4YPE A;  2BQZ A;  4J7I A;  5LSZ A;  4YNP A;  3TG4 A;  5KJK A;  2G46 A;  2QPW A; 
#chains in the Genus database with same CATH homology
 3KMJ A;  4BUP A;  3S7D A;  5ARF A;  4I51 A;  5JIN A;  3K5K A;  3RQ4 A;  4QEN A;  4QEP A;  4YND A;  4AU7 A;  4QEO A;  3S7F A;  3DAL A;  3OPE A;  2RFI A;  4WUY A;  3CBM A;  3CBP A;  4MI0 A;  5JJ0 A;  1H3I A;  5EG2 A;  3EP0 A;  4RZ0 A;  3HNA A;  5CCM A;  3S7B A;  1O9S A;  2IGQ A;  4MI5 A;  3BO5 A;  3M57 A;  3F9Y A;  3M55 A;  3QWV A;  3QWW A;  5HQ8 A;  1ZKK A;  3MO5 A;  5KJL A;  4YPU A;  3OXL A;  3M54 A;  3RU0 A;  3RJW A;  5T0M A;  3IHX A;  5T0K A;  4C1Q A;  3M5A A;  3OS5 A;  3VV0 A;  3RAY A;  5JIY A;  3SW9 A;  5TTF A;  4E47 A;  5EX3 A;  5JHN A;  3F9Z A;  1MUF A;  4J8O A;  5KJM A;  3F9X A;  1N6C A;  4FMU A;  2R3A A;  4JDS A;  3S8P A;  2O8J A;  4YPA A;  4NVQ A;  3QWP A;  3MO0 A;  3M59 A;  3MEK A;  4J7F A;  5F59 A;  3CBO A;  1MVX A;  4JLG A;  5CCL A;  5TH7 A;  5AYF A;  3KMA A;  4IJD A;  3S7J A;  3M56 A;  5F6K C;  5ARG A;  3MO2 A;  2F69 A;  4LDG A;  3KMT A;  1ML9 A;  3RIB A;  1MVH A;  5T5G A;  5HI7 A;  3DB5 A;  2JV0 A;  1MT6 A;  3VUZ A;  4J83 A;  1XQH A;  3M53 A;  4O30 A;  3F9W A;  1PEG A;  3PDN A;  3N71 A;  4NJ5 A;  4YNM A;  3SWC A;  5KJN A;  3FPD A;  5F6L A;  1N6A A;  2W5Y A;  3M58 A;  4H12 A;  3OXG A;  3OOI A;  2W5Z A;  4IJ8 A;  1N3J A;  3OXF A;  4Z4P A;  3TG5 A;  4O6F A;  5LSX A;  5TEG A;  5EX0 A;  5CPR B;  5F5E A;  4YPE A;  2BQZ A;  4J7I A;  5LSZ A;  4YNP A;  3TG4 A;  5KJK A;  2G46 A;  2QPW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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