3SWCA

Glp (g9a-like protein) set domain in complex with dnmt3ak44me2 peptide
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
261
structure length
261
Chain Sequence
VERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDCSSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELISDSEADVREEDSYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYGERFWDIKGKLFSCRCGSPKCRHS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Histone-lysine N-methyltransferase EHMT1
publication title MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 69
structure length 261
sequence length 261
chains with identical sequence B
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2011-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 3swcA00
5F6KC 3VUZA 2QPWA 5JIYA 3S7JA 2O8JA 4NJ5A 3M54A 3M57A 3QWPA 3QWWA 3M55A 4H12A 4C1QA 4NVQA 5EX0A 1MVXA 4MI0A 4YPUA 4LDGA 3IHXA 3CBMA 3SW9A 1N3JA 4QEOA 1O9SA 3S7DA 5F6LA 5JJ0A 4FMUA 4IJ8A 4IJDA 5T5GA 5CCLA 3OXGA 5JINA 2RFIA 5EX3A 5TEGA 3CBOA 3OXLA 4BUPA 5CPRB 3M58A 3N71A 3MO2A 5LSZA 3K5KA 1XQHA 2G46A 3MO0A 3QWVA 5LSXA 3M56A 4J83A 3S8PA 5TTFA 3DALA 1N6CA 4J7IA 4JDSA 2JV0A 5KJMA 3M5AA 3EP0A 3OPEA 5HI7A 3TG5A 3BO5A 4J7FA 4WUYA 2BQZA 5F5EA 5EG2A 3M53A 3F9XA 5ARFA 5KJNA 3F9WA 4QEPA 3RAYA 1PEGA 1MUFA 4I51A 5T0KA 3OS5A 4E47A 5CCMA 4Z4PA 4O30A 4YNDA 3FPDA 3PDNA 5JHNA 3HNAA 3OXFA 3MEKA 3F9YA 4MI5A 3F9ZA 3M59A 5ARGA 3S7BA 5F59A 3DB5A 1ML9A 3OOIA 3RJWA 2F69A 4O6FA 5T0MA 5KJLA 5AYFA 4JLGA 5TH7A 4YNMA 2R3AA 4J8OA 3VV0A 5HQ8A 3CBPA 3RIBA 3RU0A 1ZKKA 3KMJA 3KMTA 4YPEA 2W5ZA 4YPAA 3KMAA 3RQ4A 2IGQA 3S7FA 1H3IA 4YNPA 1MT6A 3TG4A 3SWCA 5KJKA 2W5YA 3MO5A 4AU7A 4QENA 1MVHA 4RZ0A 1N6AA
chains in the Genus database with same CATH superfamily
5F6KC 3VUZA 2QPWA 5JIYA 3S7JA 2O8JA 4NJ5A 3M54A 3M57A 3QWPA 3QWWA 3M55A 4H12A 4C1QA 4NVQA 5EX0A 1MVXA 4MI0A 4YPUA 4LDGA 3IHXA 3CBMA 3SW9A 1N3JA 4QEOA 1O9SA 3S7DA 5F6LA 5JJ0A 4FMUA 4IJ8A 4IJDA 5T5GA 5CCLA 3OXGA 5JINA 2RFIA 5EX3A 5TEGA 3CBOA 3OXLA 4BUPA 5CPRB 3M58A 3N71A 3MO2A 5LSZA 3K5KA 1XQHA 2G46A 3MO0A 3QWVA 5LSXA 3M56A 4J83A 3S8PA 5TTFA 3DALA 1N6CA 4J7IA 4JDSA 2JV0A 5KJMA 3M5AA 3EP0A 3OPEA 5HI7A 3TG5A 3BO5A 4J7FA 4WUYA 2BQZA 5F5EA 5EG2A 3M53A 3F9XA 5ARFA 5KJNA 3F9WA 4QEPA 3RAYA 1PEGA 1MUFA 4I51A 5T0KA 3OS5A 4E47A 5CCMA 4Z4PA 4O30A 4YNDA 3FPDA 3PDNA 5JHNA 3HNAA 3OXFA 3MEKA 3F9YA 4MI5A 3F9ZA 3M59A 5ARGA 3S7BA 5F59A 3DB5A 1ML9A 3OOIA 3RJWA 2F69A 4O6FA 5T0MA 5KJLA 5AYFA 4JLGA 5TH7A 4YNMA 2R3AA 4J8OA 3VV0A 5HQ8A 3CBPA 3RIBA 3RU0A 1ZKKA 3KMJA 3KMTA 4YPEA 2W5ZA 4YPAA 3KMAA 3RQ4A 2IGQA 3S7FA 1H3IA 4YNPA 1MT6A 3TG4A 3SWCA 5KJKA 2W5YA 3MO5A 4AU7A 4QENA 1MVHA 4RZ0A 1N6AA
chains in the Genus database with same CATH topology
5F6KC 3VUZA 2QPWA 5JIYA 3S7JA 2O8JA 4NJ5A 3M54A 3M57A 3QWPA 3QWWA 3M55A 4H12A 4C1QA 4NVQA 5EX0A 1MVXA 4MI0A 4YPUA 4LDGA 3IHXA 3CBMA 3SW9A 1N3JA 4QEOA 1O9SA 3S7DA 5F6LA 5JJ0A 4FMUA 4IJ8A 4IJDA 5T5GA 5CCLA 3OXGA 5JINA 2RFIA 5EX3A 5TEGA 3CBOA 3OXLA 4BUPA 5CPRB 3M58A 3N71A 3MO2A 5LSZA 3K5KA 1XQHA 2G46A 3MO0A 3QWVA 5LSXA 3M56A 4J83A 3S8PA 5TTFA 3DALA 1N6CA 4J7IA 4JDSA 2JV0A 5KJMA 3M5AA 3EP0A 3OPEA 5HI7A 3TG5A 3BO5A 4J7FA 4WUYA 2BQZA 5F5EA 5EG2A 3M53A 3F9XA 5ARFA 5KJNA 3F9WA 4QEPA 3RAYA 1PEGA 1MUFA 4I51A 5T0KA 3OS5A 4E47A 5CCMA 4Z4PA 4O30A 4YNDA 3FPDA 3PDNA 5JHNA 3HNAA 3OXFA 3MEKA 3F9YA 4MI5A 3F9ZA 3M59A 5ARGA 3S7BA 5F59A 3DB5A 1ML9A 3OOIA 3RJWA 2F69A 4O6FA 5T0MA 5KJLA 5AYFA 4JLGA 5TH7A 4YNMA 2R3AA 4J8OA 3VV0A 5HQ8A 3CBPA 3RIBA 3RU0A 1ZKKA 3KMJA 3KMTA 4YPEA 2W5ZA 4YPAA 3KMAA 3RQ4A 2IGQA 3S7FA 1H3IA 4YNPA 1MT6A 3TG4A 3SWCA 5KJKA 2W5YA 3MO5A 4AU7A 4QENA 1MVHA 4RZ0A 1N6AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5F6K C;  3VUZ A;  2QPW A;  5JIY A;  3S7J A;  2O8J A;  4NJ5 A;  3M54 A;  3M57 A;  3QWP A;  3QWW A;  3M55 A;  4H12 A;  4C1Q A;  4NVQ A;  5EX0 A;  1MVX A;  4MI0 A;  4YPU A;  4LDG A;  3IHX A;  3CBM A;  3SW9 A;  1N3J A;  4QEO A;  1O9S A;  3S7D A;  5F6L A;  5JJ0 A;  4FMU A;  4IJ8 A;  4IJD A;  5T5G A;  5CCL A;  3OXG A;  5JIN A;  2RFI A;  5EX3 A;  5TEG A;  3CBO A;  3OXL A;  4BUP A;  5CPR B;  3M58 A;  3N71 A;  3MO2 A;  5LSZ A;  3K5K A;  1XQH A;  2G46 A;  3MO0 A;  3QWV A;  5LSX A;  3M56 A;  4J83 A;  3S8P A;  5TTF A;  3DAL A;  1N6C A;  4J7I A;  4JDS A;  2JV0 A;  5KJM A;  3M5A A;  3EP0 A;  3OPE A;  5HI7 A;  3TG5 A;  3BO5 A;  4J7F A;  4WUY A;  2BQZ A;  5F5E A;  5EG2 A;  3M53 A;  3F9X A;  5ARF A;  5KJN A;  3F9W A;  4QEP A;  3RAY A;  1PEG A;  1MUF A;  4I51 A;  5T0K A;  3OS5 A;  4E47 A;  5CCM A;  4Z4P A;  4O30 A;  4YND A;  3FPD A;  3PDN A;  5JHN A;  3HNA A;  3OXF A;  3MEK A;  3F9Y A;  4MI5 A;  3F9Z A;  3M59 A;  5ARG A;  3S7B A;  5F59 A;  3DB5 A;  1ML9 A;  3OOI A;  3RJW A;  2F69 A;  4O6F A;  5T0M A;  5KJL A;  5AYF A;  4JLG A;  5TH7 A;  4YNM A;  2R3A A;  4J8O A;  3VV0 A;  5HQ8 A;  3CBP A;  3RIB A;  3RU0 A;  1ZKK A;  3KMJ A;  3KMT A;  4YPE A;  2W5Z A;  4YPA A;  3KMA A;  3RQ4 A;  2IGQ A;  3S7F A;  1H3I A;  4YNP A;  1MT6 A;  3TG4 A;  3SWC A;  5KJK A;  2W5Y A;  3MO5 A;  4AU7 A;  4QEN A;  1MVH A;  4RZ0 A;  1N6A A; 
#chains in the Genus database with same CATH topology
 5F6K C;  3VUZ A;  2QPW A;  5JIY A;  3S7J A;  2O8J A;  4NJ5 A;  3M54 A;  3M57 A;  3QWP A;  3QWW A;  3M55 A;  4H12 A;  4C1Q A;  4NVQ A;  5EX0 A;  1MVX A;  4MI0 A;  4YPU A;  4LDG A;  3IHX A;  3CBM A;  3SW9 A;  1N3J A;  4QEO A;  1O9S A;  3S7D A;  5F6L A;  5JJ0 A;  4FMU A;  4IJ8 A;  4IJD A;  5T5G A;  5CCL A;  3OXG A;  5JIN A;  2RFI A;  5EX3 A;  5TEG A;  3CBO A;  3OXL A;  4BUP A;  5CPR B;  3M58 A;  3N71 A;  3MO2 A;  5LSZ A;  3K5K A;  1XQH A;  2G46 A;  3MO0 A;  3QWV A;  5LSX A;  3M56 A;  4J83 A;  3S8P A;  5TTF A;  3DAL A;  1N6C A;  4J7I A;  4JDS A;  2JV0 A;  5KJM A;  3M5A A;  3EP0 A;  3OPE A;  5HI7 A;  3TG5 A;  3BO5 A;  4J7F A;  4WUY A;  2BQZ A;  5F5E A;  5EG2 A;  3M53 A;  3F9X A;  5ARF A;  5KJN A;  3F9W A;  4QEP A;  3RAY A;  1PEG A;  1MUF A;  4I51 A;  5T0K A;  3OS5 A;  4E47 A;  5CCM A;  4Z4P A;  4O30 A;  4YND A;  3FPD A;  3PDN A;  5JHN A;  3HNA A;  3OXF A;  3MEK A;  3F9Y A;  4MI5 A;  3F9Z A;  3M59 A;  5ARG A;  3S7B A;  5F59 A;  3DB5 A;  1ML9 A;  3OOI A;  3RJW A;  2F69 A;  4O6F A;  5T0M A;  5KJL A;  5AYF A;  4JLG A;  5TH7 A;  4YNM A;  2R3A A;  4J8O A;  3VV0 A;  5HQ8 A;  3CBP A;  3RIB A;  3RU0 A;  1ZKK A;  3KMJ A;  3KMT A;  4YPE A;  2W5Z A;  4YPA A;  3KMA A;  3RQ4 A;  2IGQ A;  3S7F A;  1H3I A;  4YNP A;  1MT6 A;  3TG4 A;  3SWC A;  5KJK A;  2W5Y A;  3MO5 A;  4AU7 A;  4QEN A;  1MVH A;  4RZ0 A;  1N6A A; 
#chains in the Genus database with same CATH homology
 5F6K C;  3VUZ A;  2QPW A;  5JIY A;  3S7J A;  2O8J A;  4NJ5 A;  3M54 A;  3M57 A;  3QWP A;  3QWW A;  3M55 A;  4H12 A;  4C1Q A;  4NVQ A;  5EX0 A;  1MVX A;  4MI0 A;  4YPU A;  4LDG A;  3IHX A;  3CBM A;  3SW9 A;  1N3J A;  4QEO A;  1O9S A;  3S7D A;  5F6L A;  5JJ0 A;  4FMU A;  4IJ8 A;  4IJD A;  5T5G A;  5CCL A;  3OXG A;  5JIN A;  2RFI A;  5EX3 A;  5TEG A;  3CBO A;  3OXL A;  4BUP A;  5CPR B;  3M58 A;  3N71 A;  3MO2 A;  5LSZ A;  3K5K A;  1XQH A;  2G46 A;  3MO0 A;  3QWV A;  5LSX A;  3M56 A;  4J83 A;  3S8P A;  5TTF A;  3DAL A;  1N6C A;  4J7I A;  4JDS A;  2JV0 A;  5KJM A;  3M5A A;  3EP0 A;  3OPE A;  5HI7 A;  3TG5 A;  3BO5 A;  4J7F A;  4WUY A;  2BQZ A;  5F5E A;  5EG2 A;  3M53 A;  3F9X A;  5ARF A;  5KJN A;  3F9W A;  4QEP A;  3RAY A;  1PEG A;  1MUF A;  4I51 A;  5T0K A;  3OS5 A;  4E47 A;  5CCM A;  4Z4P A;  4O30 A;  4YND A;  3FPD A;  3PDN A;  5JHN A;  3HNA A;  3OXF A;  3MEK A;  3F9Y A;  4MI5 A;  3F9Z A;  3M59 A;  5ARG A;  3S7B A;  5F59 A;  3DB5 A;  1ML9 A;  3OOI A;  3RJW A;  2F69 A;  4O6F A;  5T0M A;  5KJL A;  5AYF A;  4JLG A;  5TH7 A;  4YNM A;  2R3A A;  4J8O A;  3VV0 A;  5HQ8 A;  3CBP A;  3RIB A;  3RU0 A;  1ZKK A;  3KMJ A;  3KMT A;  4YPE A;  2W5Z A;  4YPA A;  3KMA A;  3RQ4 A;  2IGQ A;  3S7F A;  1H3I A;  4YNP A;  1MT6 A;  3TG4 A;  3SWC A;  5KJK A;  2W5Y A;  3MO5 A;  4AU7 A;  4QEN A;  1MVH A;  4RZ0 A;  1N6A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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