3SWCA

Glp (g9a-like protein) set domain in complex with dnmt3ak44me2 peptide
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
261
structure length
261
Chain Sequence
VERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDCSSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELISDSEADVREEDSYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYGERFWDIKGKLFSCRCGSPKCRHS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
molecule keywords Histone-lysine N-methyltransferase EHMT1
total genus 69
structure length 261
sequence length 261
chains with identical sequence B
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2011-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 3swcA00
3F9YA 3QWWA 3KMTA 5CCMA 5JINA 3OPEA 1XQHA 5KJKA 5LSXA 4QEPA 2R3AA 3M53A 5F5EA 3MO5A 3F9ZA 4YPUA 2W5YA 5KJMA 3PDNA 5KJNA 3M55A 2W5ZA 3M57A 3EP0A 3HNAA 1ZKKA 3S8PA 4C1QA 3BO5A 3SWCA 4WUYA 3TG4A 5ARGA 3CBMA 3QWVA 1MVXA 3MEKA 3F9XA 2G46A 3QWPA 5HI7A 3VUZA 3RU0A 4NJ5A 4RZ0A 3S7BA 4JDSA 3K5KA 5ARFA 3CBPA 2IGQA 3FPDA 4J8OA 1ML9A 3RQ4A 2F69A 5AYFA 3M56A 3M5AA 3RIBA 4BUPA 4I51A 5T5GA 4IJDA 5CCLA 2JV0A 5TH7A 3OXGA 4J7IA 4J7FA 4YNDA 3CBOA 4J83A 2O8JA 5T0MA 1N3JA 3KMJA 5JIYA 5JJ0A 1MT6A 4YNPA 4Z4PA 3OOIA 3SW9A 3OS5A 4JLGA 3M59A 5T0KA 5JHNA 4MI5A 5F6LA 3RAYA 3DB5A 5CPRB 4YPEA 5F59A 3OXFA 4LDGA 3N71A 4NVQA 4H12A 3VV0A 1MVHA 1H3IA 4QEOA 4AU7A 4MI0A 5F6KC 4O30A 4YNMA 5TTFA 3M58A 3DALA 2RFIA 4YPAA 5EG2A 4FMUA 3S7DA 4E47A 3S7FA 2QPWA 1MUFA 3KMAA 3TG5A 2BQZA 3MO0A 5LSZA 5HQ8A 1N6CA 3IHXA 3OXLA 4O6FA 3MO2A 3S7JA 1N6AA 5EX3A 5KJLA 4QENA 3M54A 1O9SA 5EX0A 3F9WA 3RJWA 5TEGA 1PEGA 4IJ8A
chains in the Genus database with same CATH superfamily
3F9YA 3QWWA 3KMTA 5CCMA 5JINA 3OPEA 1XQHA 5KJKA 5LSXA 4QEPA 2R3AA 3M53A 5F5EA 3MO5A 3F9ZA 4YPUA 2W5YA 5KJMA 3PDNA 5KJNA 3M55A 2W5ZA 3M57A 3EP0A 3HNAA 1ZKKA 3S8PA 4C1QA 3BO5A 3SWCA 4WUYA 3TG4A 5ARGA 3CBMA 3QWVA 1MVXA 3MEKA 3F9XA 2G46A 3QWPA 5HI7A 3VUZA 3RU0A 4NJ5A 4RZ0A 3S7BA 4JDSA 3K5KA 5ARFA 3CBPA 2IGQA 3FPDA 4J8OA 1ML9A 3RQ4A 2F69A 5AYFA 3M56A 3M5AA 3RIBA 4BUPA 4I51A 5T5GA 4IJDA 5CCLA 2JV0A 5TH7A 3OXGA 4J7IA 4J7FA 4YNDA 3CBOA 4J83A 2O8JA 5T0MA 1N3JA 3KMJA 5JIYA 5JJ0A 1MT6A 4YNPA 4Z4PA 3OOIA 3SW9A 3OS5A 4JLGA 3M59A 5T0KA 5JHNA 4MI5A 5F6LA 3RAYA 3DB5A 5CPRB 4YPEA 5F59A 3OXFA 4LDGA 3N71A 4NVQA 4H12A 3VV0A 1MVHA 1H3IA 4QEOA 4AU7A 4MI0A 5F6KC 4O30A 4YNMA 5TTFA 3M58A 3DALA 2RFIA 4YPAA 5EG2A 4FMUA 3S7DA 4E47A 3S7FA 2QPWA 1MUFA 3KMAA 3TG5A 2BQZA 3MO0A 5LSZA 5HQ8A 1N6CA 3IHXA 3OXLA 4O6FA 3MO2A 3S7JA 1N6AA 5EX3A 5KJLA 4QENA 3M54A 1O9SA 5EX0A 3F9WA 3RJWA 5TEGA 1PEGA 4IJ8A
chains in the Genus database with same CATH topology
3F9YA 3QWWA 3KMTA 5CCMA 5JINA 3OPEA 1XQHA 5KJKA 5LSXA 4QEPA 2R3AA 3M53A 5F5EA 3MO5A 3F9ZA 4YPUA 2W5YA 5KJMA 3PDNA 5KJNA 3M55A 2W5ZA 3M57A 3EP0A 3HNAA 1ZKKA 3S8PA 4C1QA 3BO5A 3SWCA 4WUYA 3TG4A 5ARGA 3CBMA 3QWVA 1MVXA 3MEKA 3F9XA 2G46A 3QWPA 5HI7A 3VUZA 3RU0A 4NJ5A 4RZ0A 3S7BA 4JDSA 3K5KA 5ARFA 3CBPA 2IGQA 3FPDA 4J8OA 1ML9A 3RQ4A 2F69A 5AYFA 3M56A 3M5AA 3RIBA 4BUPA 4I51A 5T5GA 4IJDA 5CCLA 2JV0A 5TH7A 3OXGA 4J7IA 4J7FA 4YNDA 3CBOA 4J83A 2O8JA 5T0MA 1N3JA 3KMJA 5JIYA 5JJ0A 1MT6A 4YNPA 4Z4PA 3OOIA 3SW9A 3OS5A 4JLGA 3M59A 5T0KA 5JHNA 4MI5A 5F6LA 3RAYA 3DB5A 5CPRB 4YPEA 5F59A 3OXFA 4LDGA 3N71A 4NVQA 4H12A 3VV0A 1MVHA 1H3IA 4QEOA 4AU7A 4MI0A 5F6KC 4O30A 4YNMA 5TTFA 3M58A 3DALA 2RFIA 4YPAA 5EG2A 4FMUA 3S7DA 4E47A 3S7FA 2QPWA 1MUFA 3KMAA 3TG5A 2BQZA 3MO0A 5LSZA 5HQ8A 1N6CA 3IHXA 3OXLA 4O6FA 3MO2A 3S7JA 1N6AA 5EX3A 5KJLA 4QENA 3M54A 1O9SA 5EX0A 3F9WA 3RJWA 5TEGA 1PEGA 4IJ8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F9Y A;  3QWW A;  3KMT A;  5CCM A;  5JIN A;  3OPE A;  1XQH A;  5KJK A;  5LSX A;  4QEP A;  2R3A A;  3M53 A;  5F5E A;  3MO5 A;  3F9Z A;  4YPU A;  2W5Y A;  5KJM A;  3PDN A;  5KJN A;  3M55 A;  2W5Z A;  3M57 A;  3EP0 A;  3HNA A;  1ZKK A;  3S8P A;  4C1Q A;  3BO5 A;  3SWC A;  4WUY A;  3TG4 A;  5ARG A;  3CBM A;  3QWV A;  1MVX A;  3MEK A;  3F9X A;  2G46 A;  3QWP A;  5HI7 A;  3VUZ A;  3RU0 A;  4NJ5 A;  4RZ0 A;  3S7B A;  4JDS A;  3K5K A;  5ARF A;  3CBP A;  2IGQ A;  3FPD A;  4J8O A;  1ML9 A;  3RQ4 A;  2F69 A;  5AYF A;  3M56 A;  3M5A A;  3RIB A;  4BUP A;  4I51 A;  5T5G A;  4IJD A;  5CCL A;  2JV0 A;  5TH7 A;  3OXG A;  4J7I A;  4J7F A;  4YND A;  3CBO A;  4J83 A;  2O8J A;  5T0M A;  1N3J A;  3KMJ A;  5JIY A;  5JJ0 A;  1MT6 A;  4YNP A;  4Z4P A;  3OOI A;  3SW9 A;  3OS5 A;  4JLG A;  3M59 A;  5T0K A;  5JHN A;  4MI5 A;  5F6L A;  3RAY A;  3DB5 A;  5CPR B;  4YPE A;  5F59 A;  3OXF A;  4LDG A;  3N71 A;  4NVQ A;  4H12 A;  3VV0 A;  1MVH A;  1H3I A;  4QEO A;  4AU7 A;  4MI0 A;  5F6K C;  4O30 A;  4YNM A;  5TTF A;  3M58 A;  3DAL A;  2RFI A;  4YPA A;  5EG2 A;  4FMU A;  3S7D A;  4E47 A;  3S7F A;  2QPW A;  1MUF A;  3KMA A;  3TG5 A;  2BQZ A;  3MO0 A;  5LSZ A;  5HQ8 A;  1N6C A;  3IHX A;  3OXL A;  4O6F A;  3MO2 A;  3S7J A;  1N6A A;  5EX3 A;  5KJL A;  4QEN A;  3M54 A;  1O9S A;  5EX0 A;  3F9W A;  3RJW A;  5TEG A;  1PEG A;  4IJ8 A; 
#chains in the Genus database with same CATH topology
 3F9Y A;  3QWW A;  3KMT A;  5CCM A;  5JIN A;  3OPE A;  1XQH A;  5KJK A;  5LSX A;  4QEP A;  2R3A A;  3M53 A;  5F5E A;  3MO5 A;  3F9Z A;  4YPU A;  2W5Y A;  5KJM A;  3PDN A;  5KJN A;  3M55 A;  2W5Z A;  3M57 A;  3EP0 A;  3HNA A;  1ZKK A;  3S8P A;  4C1Q A;  3BO5 A;  3SWC A;  4WUY A;  3TG4 A;  5ARG A;  3CBM A;  3QWV A;  1MVX A;  3MEK A;  3F9X A;  2G46 A;  3QWP A;  5HI7 A;  3VUZ A;  3RU0 A;  4NJ5 A;  4RZ0 A;  3S7B A;  4JDS A;  3K5K A;  5ARF A;  3CBP A;  2IGQ A;  3FPD A;  4J8O A;  1ML9 A;  3RQ4 A;  2F69 A;  5AYF A;  3M56 A;  3M5A A;  3RIB A;  4BUP A;  4I51 A;  5T5G A;  4IJD A;  5CCL A;  2JV0 A;  5TH7 A;  3OXG A;  4J7I A;  4J7F A;  4YND A;  3CBO A;  4J83 A;  2O8J A;  5T0M A;  1N3J A;  3KMJ A;  5JIY A;  5JJ0 A;  1MT6 A;  4YNP A;  4Z4P A;  3OOI A;  3SW9 A;  3OS5 A;  4JLG A;  3M59 A;  5T0K A;  5JHN A;  4MI5 A;  5F6L A;  3RAY A;  3DB5 A;  5CPR B;  4YPE A;  5F59 A;  3OXF A;  4LDG A;  3N71 A;  4NVQ A;  4H12 A;  3VV0 A;  1MVH A;  1H3I A;  4QEO A;  4AU7 A;  4MI0 A;  5F6K C;  4O30 A;  4YNM A;  5TTF A;  3M58 A;  3DAL A;  2RFI A;  4YPA A;  5EG2 A;  4FMU A;  3S7D A;  4E47 A;  3S7F A;  2QPW A;  1MUF A;  3KMA A;  3TG5 A;  2BQZ A;  3MO0 A;  5LSZ A;  5HQ8 A;  1N6C A;  3IHX A;  3OXL A;  4O6F A;  3MO2 A;  3S7J A;  1N6A A;  5EX3 A;  5KJL A;  4QEN A;  3M54 A;  1O9S A;  5EX0 A;  3F9W A;  3RJW A;  5TEG A;  1PEG A;  4IJ8 A; 
#chains in the Genus database with same CATH homology
 3F9Y A;  3QWW A;  3KMT A;  5CCM A;  5JIN A;  3OPE A;  1XQH A;  5KJK A;  5LSX A;  4QEP A;  2R3A A;  3M53 A;  5F5E A;  3MO5 A;  3F9Z A;  4YPU A;  2W5Y A;  5KJM A;  3PDN A;  5KJN A;  3M55 A;  2W5Z A;  3M57 A;  3EP0 A;  3HNA A;  1ZKK A;  3S8P A;  4C1Q A;  3BO5 A;  3SWC A;  4WUY A;  3TG4 A;  5ARG A;  3CBM A;  3QWV A;  1MVX A;  3MEK A;  3F9X A;  2G46 A;  3QWP A;  5HI7 A;  3VUZ A;  3RU0 A;  4NJ5 A;  4RZ0 A;  3S7B A;  4JDS A;  3K5K A;  5ARF A;  3CBP A;  2IGQ A;  3FPD A;  4J8O A;  1ML9 A;  3RQ4 A;  2F69 A;  5AYF A;  3M56 A;  3M5A A;  3RIB A;  4BUP A;  4I51 A;  5T5G A;  4IJD A;  5CCL A;  2JV0 A;  5TH7 A;  3OXG A;  4J7I A;  4J7F A;  4YND A;  3CBO A;  4J83 A;  2O8J A;  5T0M A;  1N3J A;  3KMJ A;  5JIY A;  5JJ0 A;  1MT6 A;  4YNP A;  4Z4P A;  3OOI A;  3SW9 A;  3OS5 A;  4JLG A;  3M59 A;  5T0K A;  5JHN A;  4MI5 A;  5F6L A;  3RAY A;  3DB5 A;  5CPR B;  4YPE A;  5F59 A;  3OXF A;  4LDG A;  3N71 A;  4NVQ A;  4H12 A;  3VV0 A;  1MVH A;  1H3I A;  4QEO A;  4AU7 A;  4MI0 A;  5F6K C;  4O30 A;  4YNM A;  5TTF A;  3M58 A;  3DAL A;  2RFI A;  4YPA A;  5EG2 A;  4FMU A;  3S7D A;  4E47 A;  3S7F A;  2QPW A;  1MUF A;  3KMA A;  3TG5 A;  2BQZ A;  3MO0 A;  5LSZ A;  5HQ8 A;  1N6C A;  3IHX A;  3OXL A;  4O6F A;  3MO2 A;  3S7J A;  1N6A A;  5EX3 A;  5KJL A;  4QEN A;  3M54 A;  1O9S A;  5EX0 A;  3F9W A;  3RJW A;  5TEG A;  1PEG A;  4IJ8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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