1MT6A

Structure of histone h3 k4-specific methyltransferase set7/9 with adohcy
Total Genus 62
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
280
structure length
280
Chain Sequence
TLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords SET9
publication title The active site of the SET domain is constructed on a knot
pubmed rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 62
structure length 280
sequence length 280
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF02493 MORN MORN repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.110.10 Mainly Beta Single Sheet Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 1mt6A01
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1mt6A02
5EG2A 4WUYA 3TG5A 3M57A 4NJ5A 3M55A 2O8JA 4YPEA 3RJWA 1MVHA 5HI7A 2QPWA 5KJLA 3M56A 3OXFA 3CBPA 5F6KC 4YPUA 5T0MA 1MUFA 5KJMA 3MO5A 3QWVA 5ARFA 5T0KA 5AYFA 4IJ8A 2JV0A 1XQHA 3S7BA 5F6LA 5CCMA 3OS5A 3M5AA 5LSXA 1MVXA 2RFIA 1N6AA 3M53A 1ZKKA 5CCLA 3N71A 4JLGA 5KJNA 3BO5A 3S7FA 2W5ZA 1N6CA 4YPAA 4I51A 4J83A 3MEKA 4NVQA 4E47A 5CPRB 4QENA 3VV0A 4Z4PA 4C1QA 2W5YA 4J8OA 4MI5A 3QWWA 5TEGA 2R3AA 4BUPA 1MT6A 4YNPA 4QEPA 4O30A 3RAYA 4O6FA 3KMTA 3RIBA 3HNAA 3M58A 3MO0A 4QEOA 3F9WA 2F69A 4YNMA 3KMJA 4YNDA 1N3JA 3F9ZA 3VUZA 3IHXA 3F9YA 2BQZA 5ARGA 3SWCA 3S7DA 3OXGA 5EX0A 3S8PA 4RZ0A 5TTFA 3OXLA 5JJ0A 4J7FA 3MO2A 3CBMA 5TH7A 3M54A 3RQ4A 5T5GA 5JIYA 3QWPA 3M59A 4H12A 3F9XA 5LSZA 3DALA 3OPEA 1ML9A 2IGQA 4AU7A 3PDNA 3KMAA 1O9SA 3CBOA 5EX3A 3RU0A 3S7JA 5KJKA 5JINA 1PEGA 1H3IA 5HQ8A 5F5EA 4FMUA 3SW9A 4JDSA 4J7IA 3K5KA 4LDGA 3TG4A 4MI0A 2G46A 4IJDA 3DB5A 3EP0A 5JHNA 5F59A 3FPDA 3OOIA
chains in the Genus database with same CATH superfamily
5EG2A 4WUYA 3TG5A 3M57A 4NJ5A 3M55A 2O8JA 4YPEA 3RJWA 1MVHA 5HI7A 2QPWA 5KJLA 3M56A 3OXFA 3CBPA 5F6KC 4YPUA 5T0MA 1MUFA 5KJMA 3MO5A 3QWVA 5ARFA 5T0KA 5AYFA 4IJ8A 2JV0A 1XQHA 3S7BA 5F6LA 5CCMA 3OS5A 3M5AA 5LSXA 1MVXA 2RFIA 1N6AA 3M53A 1ZKKA 5CCLA 3N71A 4JLGA 5KJNA 3BO5A 3S7FA 2W5ZA 1N6CA 4YPAA 4I51A 4J83A 3MEKA 4NVQA 4E47A 5CPRB 4QENA 3VV0A 4Z4PA 4C1QA 2W5YA 4J8OA 4MI5A 3QWWA 5TEGA 2R3AA 4BUPA 1MT6A 4YNPA 4QEPA 4O30A 3RAYA 4O6FA 3KMTA 3RIBA 3HNAA 3M58A 3MO0A 4QEOA 3F9WA 2F69A 4YNMA 3KMJA 4YNDA 1N3JA 3F9ZA 3VUZA 3IHXA 3F9YA 2BQZA 5ARGA 3SWCA 3S7DA 3OXGA 5EX0A 3S8PA 4RZ0A 5TTFA 3OXLA 5JJ0A 4J7FA 3MO2A 3CBMA 5TH7A 3M54A 3RQ4A 5T5GA 5JIYA 3QWPA 3M59A 4H12A 3F9XA 5LSZA 3DALA 3OPEA 1ML9A 2IGQA 4AU7A 3PDNA 3KMAA 1O9SA 3CBOA 5EX3A 3RU0A 3S7JA 5KJKA 5JINA 1PEGA 1H3IA 5HQ8A 5F5EA 4FMUA 3SW9A 4JDSA 4J7IA 3K5KA 4LDGA 3TG4A 4MI0A 2G46A 4IJDA 3DB5A 3EP0A 5JHNA 5F59A 3FPDA 3OOIA
chains in the Genus database with same CATH topology
5EG2A 4WUYA 3TG5A 3M57A 4NJ5A 3M55A 2O8JA 4YPEA 3RJWA 1MVHA 5HI7A 2QPWA 5KJLA 3M56A 3OXFA 3CBPA 5F6KC 4YPUA 5T0MA 1MUFA 5KJMA 3MO5A 3QWVA 5ARFA 5T0KA 5AYFA 4IJ8A 2JV0A 1XQHA 3S7BA 5F6LA 5CCMA 3OS5A 3M5AA 5LSXA 1MVXA 2RFIA 1N6AA 3M53A 1ZKKA 5CCLA 3N71A 4JLGA 5KJNA 3BO5A 3S7FA 2W5ZA 1N6CA 4YPAA 4I51A 4J83A 3MEKA 4NVQA 4E47A 5CPRB 4QENA 3VV0A 4Z4PA 4C1QA 2W5YA 4J8OA 4MI5A 3QWWA 5TEGA 2R3AA 4BUPA 1MT6A 4YNPA 4QEPA 4O30A 3RAYA 4O6FA 3KMTA 3RIBA 3HNAA 3M58A 3MO0A 4QEOA 3F9WA 2F69A 4YNMA 3KMJA 4YNDA 1N3JA 3F9ZA 3VUZA 3IHXA 3F9YA 2BQZA 5ARGA 3SWCA 3S7DA 3OXGA 5EX0A 3S8PA 4RZ0A 5TTFA 3OXLA 5JJ0A 4J7FA 3MO2A 3CBMA 5TH7A 3M54A 3RQ4A 5T5GA 5JIYA 3QWPA 3M59A 4H12A 3F9XA 5LSZA 3DALA 3OPEA 1ML9A 2IGQA 4AU7A 3PDNA 3KMAA 1O9SA 3CBOA 5EX3A 3RU0A 3S7JA 5KJKA 5JINA 1PEGA 1H3IA 5HQ8A 5F5EA 4FMUA 3SW9A 4JDSA 4J7IA 3K5KA 4LDGA 3TG4A 4MI0A 2G46A 4IJDA 3DB5A 3EP0A 5JHNA 5F59A 3FPDA 3OOIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EG2 A;  4WUY A;  3TG5 A;  3M57 A;  4NJ5 A;  3M55 A;  2O8J A;  4YPE A;  3RJW A;  1MVH A;  5HI7 A;  2QPW A;  5KJL A;  3M56 A;  3OXF A;  3CBP A;  5F6K C;  4YPU A;  5T0M A;  1MUF A;  5KJM A;  3MO5 A;  3QWV A;  5ARF A;  5T0K A;  5AYF A;  4IJ8 A;  2JV0 A;  1XQH A;  3S7B A;  5F6L A;  5CCM A;  3OS5 A;  3M5A A;  5LSX A;  1MVX A;  2RFI A;  1N6A A;  3M53 A;  1ZKK A;  5CCL A;  3N71 A;  4JLG A;  5KJN A;  3BO5 A;  3S7F A;  2W5Z A;  1N6C A;  4YPA A;  4I51 A;  4J83 A;  3MEK A;  4NVQ A;  4E47 A;  5CPR B;  4QEN A;  3VV0 A;  4Z4P A;  4C1Q A;  2W5Y A;  4J8O A;  4MI5 A;  3QWW A;  5TEG A;  2R3A A;  4BUP A;  1MT6 A;  4YNP A;  4QEP A;  4O30 A;  3RAY A;  4O6F A;  3KMT A;  3RIB A;  3HNA A;  3M58 A;  3MO0 A;  4QEO A;  3F9W A;  2F69 A;  4YNM A;  3KMJ A;  4YND A;  1N3J A;  3F9Z A;  3VUZ A;  3IHX A;  3F9Y A;  2BQZ A;  5ARG A;  3SWC A;  3S7D A;  3OXG A;  5EX0 A;  3S8P A;  4RZ0 A;  5TTF A;  3OXL A;  5JJ0 A;  4J7F A;  3MO2 A;  3CBM A;  5TH7 A;  3M54 A;  3RQ4 A;  5T5G A;  5JIY A;  3QWP A;  3M59 A;  4H12 A;  3F9X A;  5LSZ A;  3DAL A;  3OPE A;  1ML9 A;  2IGQ A;  4AU7 A;  3PDN A;  3KMA A;  1O9S A;  3CBO A;  5EX3 A;  3RU0 A;  3S7J A;  5KJK A;  5JIN A;  1PEG A;  1H3I A;  5HQ8 A;  5F5E A;  4FMU A;  3SW9 A;  4JDS A;  4J7I A;  3K5K A;  4LDG A;  3TG4 A;  4MI0 A;  2G46 A;  4IJD A;  3DB5 A;  3EP0 A;  5JHN A;  5F59 A;  3FPD A;  3OOI A; 
#chains in the Genus database with same CATH topology
 5EG2 A;  4WUY A;  3TG5 A;  3M57 A;  4NJ5 A;  3M55 A;  2O8J A;  4YPE A;  3RJW A;  1MVH A;  5HI7 A;  2QPW A;  5KJL A;  3M56 A;  3OXF A;  3CBP A;  5F6K C;  4YPU A;  5T0M A;  1MUF A;  5KJM A;  3MO5 A;  3QWV A;  5ARF A;  5T0K A;  5AYF A;  4IJ8 A;  2JV0 A;  1XQH A;  3S7B A;  5F6L A;  5CCM A;  3OS5 A;  3M5A A;  5LSX A;  1MVX A;  2RFI A;  1N6A A;  3M53 A;  1ZKK A;  5CCL A;  3N71 A;  4JLG A;  5KJN A;  3BO5 A;  3S7F A;  2W5Z A;  1N6C A;  4YPA A;  4I51 A;  4J83 A;  3MEK A;  4NVQ A;  4E47 A;  5CPR B;  4QEN A;  3VV0 A;  4Z4P A;  4C1Q A;  2W5Y A;  4J8O A;  4MI5 A;  3QWW A;  5TEG A;  2R3A A;  4BUP A;  1MT6 A;  4YNP A;  4QEP A;  4O30 A;  3RAY A;  4O6F A;  3KMT A;  3RIB A;  3HNA A;  3M58 A;  3MO0 A;  4QEO A;  3F9W A;  2F69 A;  4YNM A;  3KMJ A;  4YND A;  1N3J A;  3F9Z A;  3VUZ A;  3IHX A;  3F9Y A;  2BQZ A;  5ARG A;  3SWC A;  3S7D A;  3OXG A;  5EX0 A;  3S8P A;  4RZ0 A;  5TTF A;  3OXL A;  5JJ0 A;  4J7F A;  3MO2 A;  3CBM A;  5TH7 A;  3M54 A;  3RQ4 A;  5T5G A;  5JIY A;  3QWP A;  3M59 A;  4H12 A;  3F9X A;  5LSZ A;  3DAL A;  3OPE A;  1ML9 A;  2IGQ A;  4AU7 A;  3PDN A;  3KMA A;  1O9S A;  3CBO A;  5EX3 A;  3RU0 A;  3S7J A;  5KJK A;  5JIN A;  1PEG A;  1H3I A;  5HQ8 A;  5F5E A;  4FMU A;  3SW9 A;  4JDS A;  4J7I A;  3K5K A;  4LDG A;  3TG4 A;  4MI0 A;  2G46 A;  4IJD A;  3DB5 A;  3EP0 A;  5JHN A;  5F59 A;  3FPD A;  3OOI A; 
#chains in the Genus database with same CATH homology
 5EG2 A;  4WUY A;  3TG5 A;  3M57 A;  4NJ5 A;  3M55 A;  2O8J A;  4YPE A;  3RJW A;  1MVH A;  5HI7 A;  2QPW A;  5KJL A;  3M56 A;  3OXF A;  3CBP A;  5F6K C;  4YPU A;  5T0M A;  1MUF A;  5KJM A;  3MO5 A;  3QWV A;  5ARF A;  5T0K A;  5AYF A;  4IJ8 A;  2JV0 A;  1XQH A;  3S7B A;  5F6L A;  5CCM A;  3OS5 A;  3M5A A;  5LSX A;  1MVX A;  2RFI A;  1N6A A;  3M53 A;  1ZKK A;  5CCL A;  3N71 A;  4JLG A;  5KJN A;  3BO5 A;  3S7F A;  2W5Z A;  1N6C A;  4YPA A;  4I51 A;  4J83 A;  3MEK A;  4NVQ A;  4E47 A;  5CPR B;  4QEN A;  3VV0 A;  4Z4P A;  4C1Q A;  2W5Y A;  4J8O A;  4MI5 A;  3QWW A;  5TEG A;  2R3A A;  4BUP A;  1MT6 A;  4YNP A;  4QEP A;  4O30 A;  3RAY A;  4O6F A;  3KMT A;  3RIB A;  3HNA A;  3M58 A;  3MO0 A;  4QEO A;  3F9W A;  2F69 A;  4YNM A;  3KMJ A;  4YND A;  1N3J A;  3F9Z A;  3VUZ A;  3IHX A;  3F9Y A;  2BQZ A;  5ARG A;  3SWC A;  3S7D A;  3OXG A;  5EX0 A;  3S8P A;  4RZ0 A;  5TTF A;  3OXL A;  5JJ0 A;  4J7F A;  3MO2 A;  3CBM A;  5TH7 A;  3M54 A;  3RQ4 A;  5T5G A;  5JIY A;  3QWP A;  3M59 A;  4H12 A;  3F9X A;  5LSZ A;  3DAL A;  3OPE A;  1ML9 A;  2IGQ A;  4AU7 A;  3PDN A;  3KMA A;  1O9S A;  3CBO A;  5EX3 A;  3RU0 A;  3S7J A;  5KJK A;  5JIN A;  1PEG A;  1H3I A;  5HQ8 A;  5F5E A;  4FMU A;  3SW9 A;  4JDS A;  4J7I A;  3K5K A;  4LDG A;  3TG4 A;  4MI0 A;  2G46 A;  4IJD A;  3DB5 A;  3EP0 A;  5JHN A;  5F59 A;  3FPD A;  3OOI A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...