1MT6A

Structure of histone h3 k4-specific methyltransferase set7/9 with adohcy
Total Genus 62
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
280
structure length
280
Chain Sequence
TLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The active site of the SET domain is constructed on a knot
pubmed rcsb
source organism Homo sapiens
molecule tags Transferase
molecule keywords SET9
total genus 62
structure length 280
sequence length 280
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF02493 MORN MORN repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.110.10 Mainly Beta Single Sheet Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 1mt6A01
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1mt6A02
3MO5A 3IHXA 3RU0A 2W5YA 2G46A 4E47A 5CCLA 3S7BA 4NVQA 5F6LA 1ZKKA 3QWPA 4AU7A 3M58A 3K5KA 4YPUA 3DB5A 5LSXA 3S7JA 3SWCA 3M57A 3M54A 2F69A 4LDGA 3M56A 2RFIA 4J7FA 3FPDA 3OXFA 3QWWA 4QEPA 5CCMA 5HQ8A 2W5ZA 4IJ8A 3M53A 5EX0A 4RZ0A 5F6KC 4JLGA 1N6CA 2BQZA 3EP0A 4Z4PA 4QENA 4O30A 3S8PA 5KJKA 1MUFA 3OXLA 4QEOA 3VUZA 3CBOA 3SW9A 3KMJA 1N3JA 1MVXA 5ARGA 5AYFA 1ML9A 4C1QA 3M59A 3OPEA 4YNPA 3QWVA 4IJDA 1O9SA 3BO5A 1MVHA 3F9YA 5EX3A 4H12A 5T5GA 3VV0A 3F9XA 3DALA 3M5AA 3KMTA 5JHNA 5JINA 1N6AA 3F9ZA 3HNAA 3PDNA 4J7IA 4JDSA 3TG4A 4I51A 2IGQA 1XQHA 4NJ5A 5TTFA 3CBMA 4FMUA 3OOIA 5EG2A 5T0MA 3N71A 3RQ4A 3OS5A 3M55A 1H3IA 5F5EA 5KJMA 3MO2A 5T0KA 3S7DA 4YNDA 4YNMA 2O8JA 4J83A 3CBPA 3S7FA 3MO0A 4YPAA 4YPEA 3RAYA 5HI7A 1PEGA 3RIBA 5KJNA 4MI0A 5LSZA 3MEKA 4MI5A 5JIYA 4WUYA 5TEGA 5JJ0A 5ARFA 5F59A 4O6FA 4BUPA 2JV0A 5TH7A 3RJWA 1MT6A 2QPWA 4J8OA 3TG5A 2R3AA 3F9WA 5KJLA 3KMAA 5CPRB 3OXGA
chains in the Genus database with same CATH superfamily
3MO5A 3IHXA 3RU0A 2W5YA 2G46A 4E47A 5CCLA 3S7BA 4NVQA 5F6LA 1ZKKA 3QWPA 4AU7A 3M58A 3K5KA 4YPUA 3DB5A 5LSXA 3S7JA 3SWCA 3M57A 3M54A 2F69A 4LDGA 3M56A 2RFIA 4J7FA 3FPDA 3OXFA 3QWWA 4QEPA 5CCMA 5HQ8A 2W5ZA 4IJ8A 3M53A 5EX0A 4RZ0A 5F6KC 4JLGA 1N6CA 2BQZA 3EP0A 4Z4PA 4QENA 4O30A 3S8PA 5KJKA 1MUFA 3OXLA 4QEOA 3VUZA 3CBOA 3SW9A 3KMJA 1N3JA 1MVXA 5ARGA 5AYFA 1ML9A 4C1QA 3M59A 3OPEA 4YNPA 3QWVA 4IJDA 1O9SA 3BO5A 1MVHA 3F9YA 5EX3A 4H12A 5T5GA 3VV0A 3F9XA 3DALA 3M5AA 3KMTA 5JHNA 5JINA 1N6AA 3F9ZA 3HNAA 3PDNA 4J7IA 4JDSA 3TG4A 4I51A 2IGQA 1XQHA 4NJ5A 5TTFA 3CBMA 4FMUA 3OOIA 5EG2A 5T0MA 3N71A 3RQ4A 3OS5A 3M55A 1H3IA 5F5EA 5KJMA 3MO2A 5T0KA 3S7DA 4YNDA 4YNMA 2O8JA 4J83A 3CBPA 3S7FA 3MO0A 4YPAA 4YPEA 3RAYA 5HI7A 1PEGA 3RIBA 5KJNA 4MI0A 5LSZA 3MEKA 4MI5A 5JIYA 4WUYA 5TEGA 5JJ0A 5ARFA 5F59A 4O6FA 4BUPA 2JV0A 5TH7A 3RJWA 1MT6A 2QPWA 4J8OA 3TG5A 2R3AA 3F9WA 5KJLA 3KMAA 5CPRB 3OXGA
chains in the Genus database with same CATH topology
3MO5A 3IHXA 3RU0A 2W5YA 2G46A 4E47A 5CCLA 3S7BA 4NVQA 5F6LA 1ZKKA 3QWPA 4AU7A 3M58A 3K5KA 4YPUA 3DB5A 5LSXA 3S7JA 3SWCA 3M57A 3M54A 2F69A 4LDGA 3M56A 2RFIA 4J7FA 3FPDA 3OXFA 3QWWA 4QEPA 5CCMA 5HQ8A 2W5ZA 4IJ8A 3M53A 5EX0A 4RZ0A 5F6KC 4JLGA 1N6CA 2BQZA 3EP0A 4Z4PA 4QENA 4O30A 3S8PA 5KJKA 1MUFA 3OXLA 4QEOA 3VUZA 3CBOA 3SW9A 3KMJA 1N3JA 1MVXA 5ARGA 5AYFA 1ML9A 4C1QA 3M59A 3OPEA 4YNPA 3QWVA 4IJDA 1O9SA 3BO5A 1MVHA 3F9YA 5EX3A 4H12A 5T5GA 3VV0A 3F9XA 3DALA 3M5AA 3KMTA 5JHNA 5JINA 1N6AA 3F9ZA 3HNAA 3PDNA 4J7IA 4JDSA 3TG4A 4I51A 2IGQA 1XQHA 4NJ5A 5TTFA 3CBMA 4FMUA 3OOIA 5EG2A 5T0MA 3N71A 3RQ4A 3OS5A 3M55A 1H3IA 5F5EA 5KJMA 3MO2A 5T0KA 3S7DA 4YNDA 4YNMA 2O8JA 4J83A 3CBPA 3S7FA 3MO0A 4YPAA 4YPEA 3RAYA 5HI7A 1PEGA 3RIBA 5KJNA 4MI0A 5LSZA 3MEKA 4MI5A 5JIYA 4WUYA 5TEGA 5JJ0A 5ARFA 5F59A 4O6FA 4BUPA 2JV0A 5TH7A 3RJWA 1MT6A 2QPWA 4J8OA 3TG5A 2R3AA 3F9WA 5KJLA 3KMAA 5CPRB 3OXGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MO5 A;  3IHX A;  3RU0 A;  2W5Y A;  2G46 A;  4E47 A;  5CCL A;  3S7B A;  4NVQ A;  5F6L A;  1ZKK A;  3QWP A;  4AU7 A;  3M58 A;  3K5K A;  4YPU A;  3DB5 A;  5LSX A;  3S7J A;  3SWC A;  3M57 A;  3M54 A;  2F69 A;  4LDG A;  3M56 A;  2RFI A;  4J7F A;  3FPD A;  3OXF A;  3QWW A;  4QEP A;  5CCM A;  5HQ8 A;  2W5Z A;  4IJ8 A;  3M53 A;  5EX0 A;  4RZ0 A;  5F6K C;  4JLG A;  1N6C A;  2BQZ A;  3EP0 A;  4Z4P A;  4QEN A;  4O30 A;  3S8P A;  5KJK A;  1MUF A;  3OXL A;  4QEO A;  3VUZ A;  3CBO A;  3SW9 A;  3KMJ A;  1N3J A;  1MVX A;  5ARG A;  5AYF A;  1ML9 A;  4C1Q A;  3M59 A;  3OPE A;  4YNP A;  3QWV A;  4IJD A;  1O9S A;  3BO5 A;  1MVH A;  3F9Y A;  5EX3 A;  4H12 A;  5T5G A;  3VV0 A;  3F9X A;  3DAL A;  3M5A A;  3KMT A;  5JHN A;  5JIN A;  1N6A A;  3F9Z A;  3HNA A;  3PDN A;  4J7I A;  4JDS A;  3TG4 A;  4I51 A;  2IGQ A;  1XQH A;  4NJ5 A;  5TTF A;  3CBM A;  4FMU A;  3OOI A;  5EG2 A;  5T0M A;  3N71 A;  3RQ4 A;  3OS5 A;  3M55 A;  1H3I A;  5F5E A;  5KJM A;  3MO2 A;  5T0K A;  3S7D A;  4YND A;  4YNM A;  2O8J A;  4J83 A;  3CBP A;  3S7F A;  3MO0 A;  4YPA A;  4YPE A;  3RAY A;  5HI7 A;  1PEG A;  3RIB A;  5KJN A;  4MI0 A;  5LSZ A;  3MEK A;  4MI5 A;  5JIY A;  4WUY A;  5TEG A;  5JJ0 A;  5ARF A;  5F59 A;  4O6F A;  4BUP A;  2JV0 A;  5TH7 A;  3RJW A;  1MT6 A;  2QPW A;  4J8O A;  3TG5 A;  2R3A A;  3F9W A;  5KJL A;  3KMA A;  5CPR B;  3OXG A; 
#chains in the Genus database with same CATH topology
 3MO5 A;  3IHX A;  3RU0 A;  2W5Y A;  2G46 A;  4E47 A;  5CCL A;  3S7B A;  4NVQ A;  5F6L A;  1ZKK A;  3QWP A;  4AU7 A;  3M58 A;  3K5K A;  4YPU A;  3DB5 A;  5LSX A;  3S7J A;  3SWC A;  3M57 A;  3M54 A;  2F69 A;  4LDG A;  3M56 A;  2RFI A;  4J7F A;  3FPD A;  3OXF A;  3QWW A;  4QEP A;  5CCM A;  5HQ8 A;  2W5Z A;  4IJ8 A;  3M53 A;  5EX0 A;  4RZ0 A;  5F6K C;  4JLG A;  1N6C A;  2BQZ A;  3EP0 A;  4Z4P A;  4QEN A;  4O30 A;  3S8P A;  5KJK A;  1MUF A;  3OXL A;  4QEO A;  3VUZ A;  3CBO A;  3SW9 A;  3KMJ A;  1N3J A;  1MVX A;  5ARG A;  5AYF A;  1ML9 A;  4C1Q A;  3M59 A;  3OPE A;  4YNP A;  3QWV A;  4IJD A;  1O9S A;  3BO5 A;  1MVH A;  3F9Y A;  5EX3 A;  4H12 A;  5T5G A;  3VV0 A;  3F9X A;  3DAL A;  3M5A A;  3KMT A;  5JHN A;  5JIN A;  1N6A A;  3F9Z A;  3HNA A;  3PDN A;  4J7I A;  4JDS A;  3TG4 A;  4I51 A;  2IGQ A;  1XQH A;  4NJ5 A;  5TTF A;  3CBM A;  4FMU A;  3OOI A;  5EG2 A;  5T0M A;  3N71 A;  3RQ4 A;  3OS5 A;  3M55 A;  1H3I A;  5F5E A;  5KJM A;  3MO2 A;  5T0K A;  3S7D A;  4YND A;  4YNM A;  2O8J A;  4J83 A;  3CBP A;  3S7F A;  3MO0 A;  4YPA A;  4YPE A;  3RAY A;  5HI7 A;  1PEG A;  3RIB A;  5KJN A;  4MI0 A;  5LSZ A;  3MEK A;  4MI5 A;  5JIY A;  4WUY A;  5TEG A;  5JJ0 A;  5ARF A;  5F59 A;  4O6F A;  4BUP A;  2JV0 A;  5TH7 A;  3RJW A;  1MT6 A;  2QPW A;  4J8O A;  3TG5 A;  2R3A A;  3F9W A;  5KJL A;  3KMA A;  5CPR B;  3OXG A; 
#chains in the Genus database with same CATH homology
 3MO5 A;  3IHX A;  3RU0 A;  2W5Y A;  2G46 A;  4E47 A;  5CCL A;  3S7B A;  4NVQ A;  5F6L A;  1ZKK A;  3QWP A;  4AU7 A;  3M58 A;  3K5K A;  4YPU A;  3DB5 A;  5LSX A;  3S7J A;  3SWC A;  3M57 A;  3M54 A;  2F69 A;  4LDG A;  3M56 A;  2RFI A;  4J7F A;  3FPD A;  3OXF A;  3QWW A;  4QEP A;  5CCM A;  5HQ8 A;  2W5Z A;  4IJ8 A;  3M53 A;  5EX0 A;  4RZ0 A;  5F6K C;  4JLG A;  1N6C A;  2BQZ A;  3EP0 A;  4Z4P A;  4QEN A;  4O30 A;  3S8P A;  5KJK A;  1MUF A;  3OXL A;  4QEO A;  3VUZ A;  3CBO A;  3SW9 A;  3KMJ A;  1N3J A;  1MVX A;  5ARG A;  5AYF A;  1ML9 A;  4C1Q A;  3M59 A;  3OPE A;  4YNP A;  3QWV A;  4IJD A;  1O9S A;  3BO5 A;  1MVH A;  3F9Y A;  5EX3 A;  4H12 A;  5T5G A;  3VV0 A;  3F9X A;  3DAL A;  3M5A A;  3KMT A;  5JHN A;  5JIN A;  1N6A A;  3F9Z A;  3HNA A;  3PDN A;  4J7I A;  4JDS A;  3TG4 A;  4I51 A;  2IGQ A;  1XQH A;  4NJ5 A;  5TTF A;  3CBM A;  4FMU A;  3OOI A;  5EG2 A;  5T0M A;  3N71 A;  3RQ4 A;  3OS5 A;  3M55 A;  1H3I A;  5F5E A;  5KJM A;  3MO2 A;  5T0K A;  3S7D A;  4YND A;  4YNM A;  2O8J A;  4J83 A;  3CBP A;  3S7F A;  3MO0 A;  4YPA A;  4YPE A;  3RAY A;  5HI7 A;  1PEG A;  3RIB A;  5KJN A;  4MI0 A;  5LSZ A;  3MEK A;  4MI5 A;  5JIY A;  4WUY A;  5TEG A;  5JJ0 A;  5ARF A;  5F59 A;  4O6F A;  4BUP A;  2JV0 A;  5TH7 A;  3RJW A;  1MT6 A;  2QPW A;  4J8O A;  3TG5 A;  2R3A A;  3F9W A;  5KJL A;  3KMA A;  5CPR B;  3OXG A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...