1MT6A

Structure of histone h3 k4-specific methyltransferase set7/9 with adohcy
Total Genus 62
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
280
structure length
280
Chain Sequence
b'TLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGY'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords SET9
publication title The active site of the SET domain is constructed on a knot
pubmed rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 62
structure length 280
sequence length 280
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF02493 MORN MORN repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.110.10 Mainly Beta Single Sheet Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 1mt6A01
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1mt6A02
5KJLA 1O9SA 5JJ0A 3MEKA 3OPEA 5KJNA 2O8JA 4QEOA 4C1QA 5CCMA 5CCLA 3M57A 4AU7A 5ARFA 4NVQA 5JINA 3OOIA 3FPDA 1ML9A 3M5AA 3RIBA 5LSZA 1N6AA 4YPAA 5F6LA 3S8PA 5LSXA 2R3AA 3RU0A 4J7FA 3OS5A 5EX0A 5JHNA 3OXLA 5T5GA 5EX3A 3M58A 3DALA 3OXGA 3IHXA 4WUYA 5TEGA 4YNPA 3EP0A 1MUFA 4NJ5A 3VV0A 5KJKA 1MT6A 4JDSA 3SW9A 1N6CA 4O6FA 3MO5A 4Z4PA 5KJMA 3KMJA 3TG5A 3VUZA 3F9WA 1MVXA 5JIYA 3QWPA 3OXFA 3F9ZA 3RJWA 4E47A 4I51A 4J83A 2JV0A 2W5YA 4IJDA 2BQZA 3M53A 2QPWA 4J7IA 4YNMA 3N71A 3DB5A 5CPRB 5T0KA 3PDNA 2G46A 4BUPA 2RFIA 3K5KA 4H12A 5TTFA 4QENA 5EG2A 5HI7A 3M54A 4FMUA 1MVHA 3RQ4A 3QWWA 2F69A 3S7BA 3QWVA 4YPUA 1H3IA 4RZ0A 3S7FA 3KMTA 1N3JA 3HNAA 4LDGA 5F59A 3BO5A 3F9YA 4QEPA 3SWCA 5TH7A 3CBPA 5AYFA 1XQHA 3S7JA 4IJ8A 1PEGA 3M55A 3CBMA 4MI5A 3S7DA 4O30A 4JLGA 5HQ8A 1ZKKA 3RAYA 5F5EA 2IGQA 3MO0A 4YNDA 3CBOA 5ARGA 3MO2A 2W5ZA 4J8OA 5F6KC 3M59A 3F9XA 4MI0A 3M56A 5T0MA 3TG4A 4YPEA 3KMAA
chains in the Genus database with same CATH superfamily
5KJLA 1O9SA 5JJ0A 3MEKA 3OPEA 5KJNA 2O8JA 4QEOA 4C1QA 5CCMA 5CCLA 3M57A 4AU7A 5ARFA 4NVQA 5JINA 3OOIA 3FPDA 1ML9A 3M5AA 3RIBA 5LSZA 1N6AA 4YPAA 5F6LA 3S8PA 5LSXA 2R3AA 3RU0A 4J7FA 3OS5A 5EX0A 5JHNA 3OXLA 5T5GA 5EX3A 3M58A 3DALA 3OXGA 3IHXA 4WUYA 5TEGA 4YNPA 3EP0A 1MUFA 4NJ5A 3VV0A 5KJKA 1MT6A 4JDSA 3SW9A 1N6CA 4O6FA 3MO5A 4Z4PA 5KJMA 3KMJA 3TG5A 3VUZA 3F9WA 1MVXA 5JIYA 3QWPA 3OXFA 3F9ZA 3RJWA 4E47A 4I51A 4J83A 2JV0A 2W5YA 4IJDA 2BQZA 3M53A 2QPWA 4J7IA 4YNMA 3N71A 3DB5A 5CPRB 5T0KA 3PDNA 2G46A 4BUPA 2RFIA 3K5KA 4H12A 5TTFA 4QENA 5EG2A 5HI7A 3M54A 4FMUA 1MVHA 3RQ4A 3QWWA 2F69A 3S7BA 3QWVA 4YPUA 1H3IA 4RZ0A 3S7FA 3KMTA 1N3JA 3HNAA 4LDGA 5F59A 3BO5A 3F9YA 4QEPA 3SWCA 5TH7A 3CBPA 5AYFA 1XQHA 3S7JA 4IJ8A 1PEGA 3M55A 3CBMA 4MI5A 3S7DA 4O30A 4JLGA 5HQ8A 1ZKKA 3RAYA 5F5EA 2IGQA 3MO0A 4YNDA 3CBOA 5ARGA 3MO2A 2W5ZA 4J8OA 5F6KC 3M59A 3F9XA 4MI0A 3M56A 5T0MA 3TG4A 4YPEA 3KMAA
chains in the Genus database with same CATH topology
5KJLA 1O9SA 5JJ0A 3MEKA 3OPEA 5KJNA 2O8JA 4QEOA 4C1QA 5CCMA 5CCLA 3M57A 4AU7A 5ARFA 4NVQA 5JINA 3OOIA 3FPDA 1ML9A 3M5AA 3RIBA 5LSZA 1N6AA 4YPAA 5F6LA 3S8PA 5LSXA 2R3AA 3RU0A 4J7FA 3OS5A 5EX0A 5JHNA 3OXLA 5T5GA 5EX3A 3M58A 3DALA 3OXGA 3IHXA 4WUYA 5TEGA 4YNPA 3EP0A 1MUFA 4NJ5A 3VV0A 5KJKA 1MT6A 4JDSA 3SW9A 1N6CA 4O6FA 3MO5A 4Z4PA 5KJMA 3KMJA 3TG5A 3VUZA 3F9WA 1MVXA 5JIYA 3QWPA 3OXFA 3F9ZA 3RJWA 4E47A 4I51A 4J83A 2JV0A 2W5YA 4IJDA 2BQZA 3M53A 2QPWA 4J7IA 4YNMA 3N71A 3DB5A 5CPRB 5T0KA 3PDNA 2G46A 4BUPA 2RFIA 3K5KA 4H12A 5TTFA 4QENA 5EG2A 5HI7A 3M54A 4FMUA 1MVHA 3RQ4A 3QWWA 2F69A 3S7BA 3QWVA 4YPUA 1H3IA 4RZ0A 3S7FA 3KMTA 1N3JA 3HNAA 4LDGA 5F59A 3BO5A 3F9YA 4QEPA 3SWCA 5TH7A 3CBPA 5AYFA 1XQHA 3S7JA 4IJ8A 1PEGA 3M55A 3CBMA 4MI5A 3S7DA 4O30A 4JLGA 5HQ8A 1ZKKA 3RAYA 5F5EA 2IGQA 3MO0A 4YNDA 3CBOA 5ARGA 3MO2A 2W5ZA 4J8OA 5F6KC 3M59A 3F9XA 4MI0A 3M56A 5T0MA 3TG4A 4YPEA 3KMAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KJL A;  1O9S A;  5JJ0 A;  3MEK A;  3OPE A;  5KJN A;  2O8J A;  4QEO A;  4C1Q A;  5CCM A;  5CCL A;  3M57 A;  4AU7 A;  5ARF A;  4NVQ A;  5JIN A;  3OOI A;  3FPD A;  1ML9 A;  3M5A A;  3RIB A;  5LSZ A;  1N6A A;  4YPA A;  5F6L A;  3S8P A;  5LSX A;  2R3A A;  3RU0 A;  4J7F A;  3OS5 A;  5EX0 A;  5JHN A;  3OXL A;  5T5G A;  5EX3 A;  3M58 A;  3DAL A;  3OXG A;  3IHX A;  4WUY A;  5TEG A;  4YNP A;  3EP0 A;  1MUF A;  4NJ5 A;  3VV0 A;  5KJK A;  1MT6 A;  4JDS A;  3SW9 A;  1N6C A;  4O6F A;  3MO5 A;  4Z4P A;  5KJM A;  3KMJ A;  3TG5 A;  3VUZ A;  3F9W A;  1MVX A;  5JIY A;  3QWP A;  3OXF A;  3F9Z A;  3RJW A;  4E47 A;  4I51 A;  4J83 A;  2JV0 A;  2W5Y A;  4IJD A;  2BQZ A;  3M53 A;  2QPW A;  4J7I A;  4YNM A;  3N71 A;  3DB5 A;  5CPR B;  5T0K A;  3PDN A;  2G46 A;  4BUP A;  2RFI A;  3K5K A;  4H12 A;  5TTF A;  4QEN A;  5EG2 A;  5HI7 A;  3M54 A;  4FMU A;  1MVH A;  3RQ4 A;  3QWW A;  2F69 A;  3S7B A;  3QWV A;  4YPU A;  1H3I A;  4RZ0 A;  3S7F A;  3KMT A;  1N3J A;  3HNA A;  4LDG A;  5F59 A;  3BO5 A;  3F9Y A;  4QEP A;  3SWC A;  5TH7 A;  3CBP A;  5AYF A;  1XQH A;  3S7J A;  4IJ8 A;  1PEG A;  3M55 A;  3CBM A;  4MI5 A;  3S7D A;  4O30 A;  4JLG A;  5HQ8 A;  1ZKK A;  3RAY A;  5F5E A;  2IGQ A;  3MO0 A;  4YND A;  3CBO A;  5ARG A;  3MO2 A;  2W5Z A;  4J8O A;  5F6K C;  3M59 A;  3F9X A;  4MI0 A;  3M56 A;  5T0M A;  3TG4 A;  4YPE A;  3KMA A; 
#chains in the Genus database with same CATH topology
 5KJL A;  1O9S A;  5JJ0 A;  3MEK A;  3OPE A;  5KJN A;  2O8J A;  4QEO A;  4C1Q A;  5CCM A;  5CCL A;  3M57 A;  4AU7 A;  5ARF A;  4NVQ A;  5JIN A;  3OOI A;  3FPD A;  1ML9 A;  3M5A A;  3RIB A;  5LSZ A;  1N6A A;  4YPA A;  5F6L A;  3S8P A;  5LSX A;  2R3A A;  3RU0 A;  4J7F A;  3OS5 A;  5EX0 A;  5JHN A;  3OXL A;  5T5G A;  5EX3 A;  3M58 A;  3DAL A;  3OXG A;  3IHX A;  4WUY A;  5TEG A;  4YNP A;  3EP0 A;  1MUF A;  4NJ5 A;  3VV0 A;  5KJK A;  1MT6 A;  4JDS A;  3SW9 A;  1N6C A;  4O6F A;  3MO5 A;  4Z4P A;  5KJM A;  3KMJ A;  3TG5 A;  3VUZ A;  3F9W A;  1MVX A;  5JIY A;  3QWP A;  3OXF A;  3F9Z A;  3RJW A;  4E47 A;  4I51 A;  4J83 A;  2JV0 A;  2W5Y A;  4IJD A;  2BQZ A;  3M53 A;  2QPW A;  4J7I A;  4YNM A;  3N71 A;  3DB5 A;  5CPR B;  5T0K A;  3PDN A;  2G46 A;  4BUP A;  2RFI A;  3K5K A;  4H12 A;  5TTF A;  4QEN A;  5EG2 A;  5HI7 A;  3M54 A;  4FMU A;  1MVH A;  3RQ4 A;  3QWW A;  2F69 A;  3S7B A;  3QWV A;  4YPU A;  1H3I A;  4RZ0 A;  3S7F A;  3KMT A;  1N3J A;  3HNA A;  4LDG A;  5F59 A;  3BO5 A;  3F9Y A;  4QEP A;  3SWC A;  5TH7 A;  3CBP A;  5AYF A;  1XQH A;  3S7J A;  4IJ8 A;  1PEG A;  3M55 A;  3CBM A;  4MI5 A;  3S7D A;  4O30 A;  4JLG A;  5HQ8 A;  1ZKK A;  3RAY A;  5F5E A;  2IGQ A;  3MO0 A;  4YND A;  3CBO A;  5ARG A;  3MO2 A;  2W5Z A;  4J8O A;  5F6K C;  3M59 A;  3F9X A;  4MI0 A;  3M56 A;  5T0M A;  3TG4 A;  4YPE A;  3KMA A; 
#chains in the Genus database with same CATH homology
 5KJL A;  1O9S A;  5JJ0 A;  3MEK A;  3OPE A;  5KJN A;  2O8J A;  4QEO A;  4C1Q A;  5CCM A;  5CCL A;  3M57 A;  4AU7 A;  5ARF A;  4NVQ A;  5JIN A;  3OOI A;  3FPD A;  1ML9 A;  3M5A A;  3RIB A;  5LSZ A;  1N6A A;  4YPA A;  5F6L A;  3S8P A;  5LSX A;  2R3A A;  3RU0 A;  4J7F A;  3OS5 A;  5EX0 A;  5JHN A;  3OXL A;  5T5G A;  5EX3 A;  3M58 A;  3DAL A;  3OXG A;  3IHX A;  4WUY A;  5TEG A;  4YNP A;  3EP0 A;  1MUF A;  4NJ5 A;  3VV0 A;  5KJK A;  1MT6 A;  4JDS A;  3SW9 A;  1N6C A;  4O6F A;  3MO5 A;  4Z4P A;  5KJM A;  3KMJ A;  3TG5 A;  3VUZ A;  3F9W A;  1MVX A;  5JIY A;  3QWP A;  3OXF A;  3F9Z A;  3RJW A;  4E47 A;  4I51 A;  4J83 A;  2JV0 A;  2W5Y A;  4IJD A;  2BQZ A;  3M53 A;  2QPW A;  4J7I A;  4YNM A;  3N71 A;  3DB5 A;  5CPR B;  5T0K A;  3PDN A;  2G46 A;  4BUP A;  2RFI A;  3K5K A;  4H12 A;  5TTF A;  4QEN A;  5EG2 A;  5HI7 A;  3M54 A;  4FMU A;  1MVH A;  3RQ4 A;  3QWW A;  2F69 A;  3S7B A;  3QWV A;  4YPU A;  1H3I A;  4RZ0 A;  3S7F A;  3KMT A;  1N3J A;  3HNA A;  4LDG A;  5F59 A;  3BO5 A;  3F9Y A;  4QEP A;  3SWC A;  5TH7 A;  3CBP A;  5AYF A;  1XQH A;  3S7J A;  4IJ8 A;  1PEG A;  3M55 A;  3CBM A;  4MI5 A;  3S7D A;  4O30 A;  4JLG A;  5HQ8 A;  1ZKK A;  3RAY A;  5F5E A;  2IGQ A;  3MO0 A;  4YND A;  3CBO A;  5ARG A;  3MO2 A;  2W5Z A;  4J8O A;  5F6K C;  3M59 A;  3F9X A;  4MI0 A;  3M56 A;  5T0M A;  3TG4 A;  4YPE A;  3KMA A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...