1N6CA

Structure of set7/9
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
285
structure length
283
Chain Sequence
b'GGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYSPPGKSGPEAPEWYQVELKAFQAT'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords SET domain-containing protein 7
molecule tags Transferase
source organism Homo sapiens
publication title Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet
pubmed doi rcsb
total genus 64
structure length 283
sequence length 285
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF02493 MORN MORN repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.110.10 Mainly Beta Single Sheet Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 1n6cA01
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1n6cA02
5KJKA 3MEKA 3M55A 5HQ8A 1N3JA 3F9XA 4RZ0A 4H12A 3FPDA 4QEOA 3RIBA 3BO5A 2G46A 1N6AA 3S7FA 3S7JA 3CBMA 4J7IA 5JINA 1MT6A 3M59A 3M53A 4YPEA 4QEPA 4I51A 4MI5A 5JJ0A 5CPRB 3OPEA 2RFIA 3OXGA 1H3IA 1N6CA 3KMAA 1MVHA 3OOIA 4NJ5A 2F69A 4QENA 2R3AA 3KMJA 5F6LA 1XQHA 3QWPA 3MO5A 3DB5A 3F9ZA 4BUPA 3M56A 4MI0A 3M57A 3MO0A 4IJDA 4YNPA 3S7DA 1ZKKA 3N71A 3S8PA 5T0KA 2W5YA 5CCMA 5KJNA 5F6KC 4YPAA 4IJ8A 3IHXA 1PEGA 4WUYA 5F59A 3VUZA 5LSZA 5T5GA 4NVQA 3DALA 4YNDA 3M5AA 1ML9A 2O8JA 3KMTA 2BQZA 4O6FA 2QPWA 3VV0A 5ARFA 5EX0A 3M54A 5JIYA 3EP0A 1MVXA 3RJWA 3RQ4A 4JDSA 3CBPA 3F9WA 5JHNA 4YPUA 2JV0A 5F5EA 3HNAA 4C1QA 3RU0A 1MUFA 5TH7A 3SW9A 3S7BA 4YNMA 4LDGA 5KJMA 4J7FA 2W5ZA 4AU7A 3CBOA 3PDNA 5HI7A 5EG2A 5AYFA 5ARGA 5KJLA 3RAYA 3TG4A 3OS5A 3SWCA 4J8OA 4O30A 4E47A 3OXLA 1O9SA 5EX3A 5TEGA 3K5KA 4Z4PA 3TG5A 3QWWA 5LSXA 3OXFA 3M58A 5CCLA 5TTFA 5T0MA 4JLGA 3MO2A 3QWVA 3F9YA 4FMUA 4J83A 2IGQA
chains in the Genus database with same CATH superfamily
5KJKA 3MEKA 3M55A 5HQ8A 1N3JA 3F9XA 4RZ0A 4H12A 3FPDA 4QEOA 3RIBA 3BO5A 2G46A 1N6AA 3S7FA 3S7JA 3CBMA 4J7IA 5JINA 1MT6A 3M59A 3M53A 4YPEA 4QEPA 4I51A 4MI5A 5JJ0A 5CPRB 3OPEA 2RFIA 3OXGA 1H3IA 1N6CA 3KMAA 1MVHA 3OOIA 4NJ5A 2F69A 4QENA 2R3AA 3KMJA 5F6LA 1XQHA 3QWPA 3MO5A 3DB5A 3F9ZA 4BUPA 3M56A 4MI0A 3M57A 3MO0A 4IJDA 4YNPA 3S7DA 1ZKKA 3N71A 3S8PA 5T0KA 2W5YA 5CCMA 5KJNA 5F6KC 4YPAA 4IJ8A 3IHXA 1PEGA 4WUYA 5F59A 3VUZA 5LSZA 5T5GA 4NVQA 3DALA 4YNDA 3M5AA 1ML9A 2O8JA 3KMTA 2BQZA 4O6FA 2QPWA 3VV0A 5ARFA 5EX0A 3M54A 5JIYA 3EP0A 1MVXA 3RJWA 3RQ4A 4JDSA 3CBPA 3F9WA 5JHNA 4YPUA 2JV0A 5F5EA 3HNAA 4C1QA 3RU0A 1MUFA 5TH7A 3SW9A 3S7BA 4YNMA 4LDGA 5KJMA 4J7FA 2W5ZA 4AU7A 3CBOA 3PDNA 5HI7A 5EG2A 5AYFA 5ARGA 5KJLA 3RAYA 3TG4A 3OS5A 3SWCA 4J8OA 4O30A 4E47A 3OXLA 1O9SA 5EX3A 5TEGA 3K5KA 4Z4PA 3TG5A 3QWWA 5LSXA 3OXFA 3M58A 5CCLA 5TTFA 5T0MA 4JLGA 3MO2A 3QWVA 3F9YA 4FMUA 4J83A 2IGQA
chains in the Genus database with same CATH topology
5KJKA 3MEKA 3M55A 5HQ8A 1N3JA 3F9XA 4RZ0A 4H12A 3FPDA 4QEOA 3RIBA 3BO5A 2G46A 1N6AA 3S7FA 3S7JA 3CBMA 4J7IA 5JINA 1MT6A 3M59A 3M53A 4YPEA 4QEPA 4I51A 4MI5A 5JJ0A 5CPRB 3OPEA 2RFIA 3OXGA 1H3IA 1N6CA 3KMAA 1MVHA 3OOIA 4NJ5A 2F69A 4QENA 2R3AA 3KMJA 5F6LA 1XQHA 3QWPA 3MO5A 3DB5A 3F9ZA 4BUPA 3M56A 4MI0A 3M57A 3MO0A 4IJDA 4YNPA 3S7DA 1ZKKA 3N71A 3S8PA 5T0KA 2W5YA 5CCMA 5KJNA 5F6KC 4YPAA 4IJ8A 3IHXA 1PEGA 4WUYA 5F59A 3VUZA 5LSZA 5T5GA 4NVQA 3DALA 4YNDA 3M5AA 1ML9A 2O8JA 3KMTA 2BQZA 4O6FA 2QPWA 3VV0A 5ARFA 5EX0A 3M54A 5JIYA 3EP0A 1MVXA 3RJWA 3RQ4A 4JDSA 3CBPA 3F9WA 5JHNA 4YPUA 2JV0A 5F5EA 3HNAA 4C1QA 3RU0A 1MUFA 5TH7A 3SW9A 3S7BA 4YNMA 4LDGA 5KJMA 4J7FA 2W5ZA 4AU7A 3CBOA 3PDNA 5HI7A 5EG2A 5AYFA 5ARGA 5KJLA 3RAYA 3TG4A 3OS5A 3SWCA 4J8OA 4O30A 4E47A 3OXLA 1O9SA 5EX3A 5TEGA 3K5KA 4Z4PA 3TG5A 3QWWA 5LSXA 3OXFA 3M58A 5CCLA 5TTFA 5T0MA 4JLGA 3MO2A 3QWVA 3F9YA 4FMUA 4J83A 2IGQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KJK A;  3MEK A;  3M55 A;  5HQ8 A;  1N3J A;  3F9X A;  4RZ0 A;  4H12 A;  3FPD A;  4QEO A;  3RIB A;  3BO5 A;  2G46 A;  1N6A A;  3S7F A;  3S7J A;  3CBM A;  4J7I A;  5JIN A;  1MT6 A;  3M59 A;  3M53 A;  4YPE A;  4QEP A;  4I51 A;  4MI5 A;  5JJ0 A;  5CPR B;  3OPE A;  2RFI A;  3OXG A;  1H3I A;  1N6C A;  3KMA A;  1MVH A;  3OOI A;  4NJ5 A;  2F69 A;  4QEN A;  2R3A A;  3KMJ A;  5F6L A;  1XQH A;  3QWP A;  3MO5 A;  3DB5 A;  3F9Z A;  4BUP A;  3M56 A;  4MI0 A;  3M57 A;  3MO0 A;  4IJD A;  4YNP A;  3S7D A;  1ZKK A;  3N71 A;  3S8P A;  5T0K A;  2W5Y A;  5CCM A;  5KJN A;  5F6K C;  4YPA A;  4IJ8 A;  3IHX A;  1PEG A;  4WUY A;  5F59 A;  3VUZ A;  5LSZ A;  5T5G A;  4NVQ A;  3DAL A;  4YND A;  3M5A A;  1ML9 A;  2O8J A;  3KMT A;  2BQZ A;  4O6F A;  2QPW A;  3VV0 A;  5ARF A;  5EX0 A;  3M54 A;  5JIY A;  3EP0 A;  1MVX A;  3RJW A;  3RQ4 A;  4JDS A;  3CBP A;  3F9W A;  5JHN A;  4YPU A;  2JV0 A;  5F5E A;  3HNA A;  4C1Q A;  3RU0 A;  1MUF A;  5TH7 A;  3SW9 A;  3S7B A;  4YNM A;  4LDG A;  5KJM A;  4J7F A;  2W5Z A;  4AU7 A;  3CBO A;  3PDN A;  5HI7 A;  5EG2 A;  5AYF A;  5ARG A;  5KJL A;  3RAY A;  3TG4 A;  3OS5 A;  3SWC A;  4J8O A;  4O30 A;  4E47 A;  3OXL A;  1O9S A;  5EX3 A;  5TEG A;  3K5K A;  4Z4P A;  3TG5 A;  3QWW A;  5LSX A;  3OXF A;  3M58 A;  5CCL A;  5TTF A;  5T0M A;  4JLG A;  3MO2 A;  3QWV A;  3F9Y A;  4FMU A;  4J83 A;  2IGQ A; 
#chains in the Genus database with same CATH topology
 5KJK A;  3MEK A;  3M55 A;  5HQ8 A;  1N3J A;  3F9X A;  4RZ0 A;  4H12 A;  3FPD A;  4QEO A;  3RIB A;  3BO5 A;  2G46 A;  1N6A A;  3S7F A;  3S7J A;  3CBM A;  4J7I A;  5JIN A;  1MT6 A;  3M59 A;  3M53 A;  4YPE A;  4QEP A;  4I51 A;  4MI5 A;  5JJ0 A;  5CPR B;  3OPE A;  2RFI A;  3OXG A;  1H3I A;  1N6C A;  3KMA A;  1MVH A;  3OOI A;  4NJ5 A;  2F69 A;  4QEN A;  2R3A A;  3KMJ A;  5F6L A;  1XQH A;  3QWP A;  3MO5 A;  3DB5 A;  3F9Z A;  4BUP A;  3M56 A;  4MI0 A;  3M57 A;  3MO0 A;  4IJD A;  4YNP A;  3S7D A;  1ZKK A;  3N71 A;  3S8P A;  5T0K A;  2W5Y A;  5CCM A;  5KJN A;  5F6K C;  4YPA A;  4IJ8 A;  3IHX A;  1PEG A;  4WUY A;  5F59 A;  3VUZ A;  5LSZ A;  5T5G A;  4NVQ A;  3DAL A;  4YND A;  3M5A A;  1ML9 A;  2O8J A;  3KMT A;  2BQZ A;  4O6F A;  2QPW A;  3VV0 A;  5ARF A;  5EX0 A;  3M54 A;  5JIY A;  3EP0 A;  1MVX A;  3RJW A;  3RQ4 A;  4JDS A;  3CBP A;  3F9W A;  5JHN A;  4YPU A;  2JV0 A;  5F5E A;  3HNA A;  4C1Q A;  3RU0 A;  1MUF A;  5TH7 A;  3SW9 A;  3S7B A;  4YNM A;  4LDG A;  5KJM A;  4J7F A;  2W5Z A;  4AU7 A;  3CBO A;  3PDN A;  5HI7 A;  5EG2 A;  5AYF A;  5ARG A;  5KJL A;  3RAY A;  3TG4 A;  3OS5 A;  3SWC A;  4J8O A;  4O30 A;  4E47 A;  3OXL A;  1O9S A;  5EX3 A;  5TEG A;  3K5K A;  4Z4P A;  3TG5 A;  3QWW A;  5LSX A;  3OXF A;  3M58 A;  5CCL A;  5TTF A;  5T0M A;  4JLG A;  3MO2 A;  3QWV A;  3F9Y A;  4FMU A;  4J83 A;  2IGQ A; 
#chains in the Genus database with same CATH homology
 5KJK A;  3MEK A;  3M55 A;  5HQ8 A;  1N3J A;  3F9X A;  4RZ0 A;  4H12 A;  3FPD A;  4QEO A;  3RIB A;  3BO5 A;  2G46 A;  1N6A A;  3S7F A;  3S7J A;  3CBM A;  4J7I A;  5JIN A;  1MT6 A;  3M59 A;  3M53 A;  4YPE A;  4QEP A;  4I51 A;  4MI5 A;  5JJ0 A;  5CPR B;  3OPE A;  2RFI A;  3OXG A;  1H3I A;  1N6C A;  3KMA A;  1MVH A;  3OOI A;  4NJ5 A;  2F69 A;  4QEN A;  2R3A A;  3KMJ A;  5F6L A;  1XQH A;  3QWP A;  3MO5 A;  3DB5 A;  3F9Z A;  4BUP A;  3M56 A;  4MI0 A;  3M57 A;  3MO0 A;  4IJD A;  4YNP A;  3S7D A;  1ZKK A;  3N71 A;  3S8P A;  5T0K A;  2W5Y A;  5CCM A;  5KJN A;  5F6K C;  4YPA A;  4IJ8 A;  3IHX A;  1PEG A;  4WUY A;  5F59 A;  3VUZ A;  5LSZ A;  5T5G A;  4NVQ A;  3DAL A;  4YND A;  3M5A A;  1ML9 A;  2O8J A;  3KMT A;  2BQZ A;  4O6F A;  2QPW A;  3VV0 A;  5ARF A;  5EX0 A;  3M54 A;  5JIY A;  3EP0 A;  1MVX A;  3RJW A;  3RQ4 A;  4JDS A;  3CBP A;  3F9W A;  5JHN A;  4YPU A;  2JV0 A;  5F5E A;  3HNA A;  4C1Q A;  3RU0 A;  1MUF A;  5TH7 A;  3SW9 A;  3S7B A;  4YNM A;  4LDG A;  5KJM A;  4J7F A;  2W5Z A;  4AU7 A;  3CBO A;  3PDN A;  5HI7 A;  5EG2 A;  5AYF A;  5ARG A;  5KJL A;  3RAY A;  3TG4 A;  3OS5 A;  3SWC A;  4J8O A;  4O30 A;  4E47 A;  3OXL A;  1O9S A;  5EX3 A;  5TEG A;  3K5K A;  4Z4P A;  3TG5 A;  3QWW A;  5LSX A;  3OXF A;  3M58 A;  5CCL A;  5TTF A;  5T0M A;  4JLG A;  3MO2 A;  3QWV A;  3F9Y A;  4FMU A;  4J83 A;  2IGQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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