1N6CA

Structure of set7/9
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
285
structure length
283
Chain Sequence
GGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYSPPGKSGPEAPEWYQVELKAFQAT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords SET domain-containing protein 7
publication title Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 64
structure length 283
sequence length 285
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF02493 MORN MORN repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.110.10 Mainly Beta Single Sheet Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 1n6cA01
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1n6cA02
3F9YA 1ML9A 3RAYA 5T0MA 4AU7A 3DALA 4C1QA 4J7IA 5JJ0A 5KJMA 5KJKA 3M5AA 4QENA 3F9WA 5KJNA 1MT6A 4J7FA 2JV0A 3SWCA 1N6AA 1O9SA 3RQ4A 3KMAA 5T5GA 3MO5A 5TH7A 3M57A 3QWVA 5F6LA 1N6CA 4QEOA 3S7FA 5LSZA 3OXFA 4J8OA 3M55A 2RFIA 3VUZA 3BO5A 3KMTA 5F5EA 3MO0A 4I51A 4YPUA 4O30A 3MEKA 3FPDA 3S7BA 1H3IA 4NJ5A 4YPAA 4O6FA 1MVXA 4YPEA 3IHXA 3KMJA 4J83A 5LSXA 3M59A 4IJDA 1MVHA 3EP0A 5CCMA 5KJLA 2G46A 5AYFA 3M56A 5HQ8A 2W5ZA 3MO2A 5ARGA 3N71A 5JIYA 3S7DA 3HNAA 3QWWA 3OOIA 5ARFA 3K5KA 4JDSA 3TG4A 4YNDA 5HI7A 4WUYA 4MI0A 3DB5A 3PDNA 2QPWA 1MUFA 3RU0A 1N3JA 3OXLA 5EX3A 5TTFA 4YNPA 5TEGA 4H12A 3QWPA 3OS5A 3S8PA 5T0KA 2R3AA 3CBOA 3TG5A 3CBMA 3M58A 4FMUA 4NVQA 1XQHA 3RIBA 4E47A 2BQZA 5JHNA 3VV0A 2W5YA 4IJ8A 1PEGA 2IGQA 3M54A 5CPRB 4LDGA 4RZ0A 3RJWA 4JLGA 4YNMA 5F6KC 3SW9A 4BUPA 5EX0A 3OXGA 1ZKKA 4Z4PA 4MI5A 2F69A 5EG2A 3CBPA 2O8JA 5F59A 3S7JA 4QEPA 3F9XA 5CCLA 3M53A 5JINA 3F9ZA 3OPEA
chains in the Genus database with same CATH superfamily
3F9YA 1ML9A 3RAYA 5T0MA 4AU7A 3DALA 4C1QA 4J7IA 5JJ0A 5KJMA 5KJKA 3M5AA 4QENA 3F9WA 5KJNA 1MT6A 4J7FA 2JV0A 3SWCA 1N6AA 1O9SA 3RQ4A 3KMAA 5T5GA 3MO5A 5TH7A 3M57A 3QWVA 5F6LA 1N6CA 4QEOA 3S7FA 5LSZA 3OXFA 4J8OA 3M55A 2RFIA 3VUZA 3BO5A 3KMTA 5F5EA 3MO0A 4I51A 4YPUA 4O30A 3MEKA 3FPDA 3S7BA 1H3IA 4NJ5A 4YPAA 4O6FA 1MVXA 4YPEA 3IHXA 3KMJA 4J83A 5LSXA 3M59A 4IJDA 1MVHA 3EP0A 5CCMA 5KJLA 2G46A 5AYFA 3M56A 5HQ8A 2W5ZA 3MO2A 5ARGA 3N71A 5JIYA 3S7DA 3HNAA 3QWWA 3OOIA 5ARFA 3K5KA 4JDSA 3TG4A 4YNDA 5HI7A 4WUYA 4MI0A 3DB5A 3PDNA 2QPWA 1MUFA 3RU0A 1N3JA 3OXLA 5EX3A 5TTFA 4YNPA 5TEGA 4H12A 3QWPA 3OS5A 3S8PA 5T0KA 2R3AA 3CBOA 3TG5A 3CBMA 3M58A 4FMUA 4NVQA 1XQHA 3RIBA 4E47A 2BQZA 5JHNA 3VV0A 2W5YA 4IJ8A 1PEGA 2IGQA 3M54A 5CPRB 4LDGA 4RZ0A 3RJWA 4JLGA 4YNMA 5F6KC 3SW9A 4BUPA 5EX0A 3OXGA 1ZKKA 4Z4PA 4MI5A 2F69A 5EG2A 3CBPA 2O8JA 5F59A 3S7JA 4QEPA 3F9XA 5CCLA 3M53A 5JINA 3F9ZA 3OPEA
chains in the Genus database with same CATH topology
3F9YA 1ML9A 3RAYA 5T0MA 4AU7A 3DALA 4C1QA 4J7IA 5JJ0A 5KJMA 5KJKA 3M5AA 4QENA 3F9WA 5KJNA 1MT6A 4J7FA 2JV0A 3SWCA 1N6AA 1O9SA 3RQ4A 3KMAA 5T5GA 3MO5A 5TH7A 3M57A 3QWVA 5F6LA 1N6CA 4QEOA 3S7FA 5LSZA 3OXFA 4J8OA 3M55A 2RFIA 3VUZA 3BO5A 3KMTA 5F5EA 3MO0A 4I51A 4YPUA 4O30A 3MEKA 3FPDA 3S7BA 1H3IA 4NJ5A 4YPAA 4O6FA 1MVXA 4YPEA 3IHXA 3KMJA 4J83A 5LSXA 3M59A 4IJDA 1MVHA 3EP0A 5CCMA 5KJLA 2G46A 5AYFA 3M56A 5HQ8A 2W5ZA 3MO2A 5ARGA 3N71A 5JIYA 3S7DA 3HNAA 3QWWA 3OOIA 5ARFA 3K5KA 4JDSA 3TG4A 4YNDA 5HI7A 4WUYA 4MI0A 3DB5A 3PDNA 2QPWA 1MUFA 3RU0A 1N3JA 3OXLA 5EX3A 5TTFA 4YNPA 5TEGA 4H12A 3QWPA 3OS5A 3S8PA 5T0KA 2R3AA 3CBOA 3TG5A 3CBMA 3M58A 4FMUA 4NVQA 1XQHA 3RIBA 4E47A 2BQZA 5JHNA 3VV0A 2W5YA 4IJ8A 1PEGA 2IGQA 3M54A 5CPRB 4LDGA 4RZ0A 3RJWA 4JLGA 4YNMA 5F6KC 3SW9A 4BUPA 5EX0A 3OXGA 1ZKKA 4Z4PA 4MI5A 2F69A 5EG2A 3CBPA 2O8JA 5F59A 3S7JA 4QEPA 3F9XA 5CCLA 3M53A 5JINA 3F9ZA 3OPEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F9Y A;  1ML9 A;  3RAY A;  5T0M A;  4AU7 A;  3DAL A;  4C1Q A;  4J7I A;  5JJ0 A;  5KJM A;  5KJK A;  3M5A A;  4QEN A;  3F9W A;  5KJN A;  1MT6 A;  4J7F A;  2JV0 A;  3SWC A;  1N6A A;  1O9S A;  3RQ4 A;  3KMA A;  5T5G A;  3MO5 A;  5TH7 A;  3M57 A;  3QWV A;  5F6L A;  1N6C A;  4QEO A;  3S7F A;  5LSZ A;  3OXF A;  4J8O A;  3M55 A;  2RFI A;  3VUZ A;  3BO5 A;  3KMT A;  5F5E A;  3MO0 A;  4I51 A;  4YPU A;  4O30 A;  3MEK A;  3FPD A;  3S7B A;  1H3I A;  4NJ5 A;  4YPA A;  4O6F A;  1MVX A;  4YPE A;  3IHX A;  3KMJ A;  4J83 A;  5LSX A;  3M59 A;  4IJD A;  1MVH A;  3EP0 A;  5CCM A;  5KJL A;  2G46 A;  5AYF A;  3M56 A;  5HQ8 A;  2W5Z A;  3MO2 A;  5ARG A;  3N71 A;  5JIY A;  3S7D A;  3HNA A;  3QWW A;  3OOI A;  5ARF A;  3K5K A;  4JDS A;  3TG4 A;  4YND A;  5HI7 A;  4WUY A;  4MI0 A;  3DB5 A;  3PDN A;  2QPW A;  1MUF A;  3RU0 A;  1N3J A;  3OXL A;  5EX3 A;  5TTF A;  4YNP A;  5TEG A;  4H12 A;  3QWP A;  3OS5 A;  3S8P A;  5T0K A;  2R3A A;  3CBO A;  3TG5 A;  3CBM A;  3M58 A;  4FMU A;  4NVQ A;  1XQH A;  3RIB A;  4E47 A;  2BQZ A;  5JHN A;  3VV0 A;  2W5Y A;  4IJ8 A;  1PEG A;  2IGQ A;  3M54 A;  5CPR B;  4LDG A;  4RZ0 A;  3RJW A;  4JLG A;  4YNM A;  5F6K C;  3SW9 A;  4BUP A;  5EX0 A;  3OXG A;  1ZKK A;  4Z4P A;  4MI5 A;  2F69 A;  5EG2 A;  3CBP A;  2O8J A;  5F59 A;  3S7J A;  4QEP A;  3F9X A;  5CCL A;  3M53 A;  5JIN A;  3F9Z A;  3OPE A; 
#chains in the Genus database with same CATH topology
 3F9Y A;  1ML9 A;  3RAY A;  5T0M A;  4AU7 A;  3DAL A;  4C1Q A;  4J7I A;  5JJ0 A;  5KJM A;  5KJK A;  3M5A A;  4QEN A;  3F9W A;  5KJN A;  1MT6 A;  4J7F A;  2JV0 A;  3SWC A;  1N6A A;  1O9S A;  3RQ4 A;  3KMA A;  5T5G A;  3MO5 A;  5TH7 A;  3M57 A;  3QWV A;  5F6L A;  1N6C A;  4QEO A;  3S7F A;  5LSZ A;  3OXF A;  4J8O A;  3M55 A;  2RFI A;  3VUZ A;  3BO5 A;  3KMT A;  5F5E A;  3MO0 A;  4I51 A;  4YPU A;  4O30 A;  3MEK A;  3FPD A;  3S7B A;  1H3I A;  4NJ5 A;  4YPA A;  4O6F A;  1MVX A;  4YPE A;  3IHX A;  3KMJ A;  4J83 A;  5LSX A;  3M59 A;  4IJD A;  1MVH A;  3EP0 A;  5CCM A;  5KJL A;  2G46 A;  5AYF A;  3M56 A;  5HQ8 A;  2W5Z A;  3MO2 A;  5ARG A;  3N71 A;  5JIY A;  3S7D A;  3HNA A;  3QWW A;  3OOI A;  5ARF A;  3K5K A;  4JDS A;  3TG4 A;  4YND A;  5HI7 A;  4WUY A;  4MI0 A;  3DB5 A;  3PDN A;  2QPW A;  1MUF A;  3RU0 A;  1N3J A;  3OXL A;  5EX3 A;  5TTF A;  4YNP A;  5TEG A;  4H12 A;  3QWP A;  3OS5 A;  3S8P A;  5T0K A;  2R3A A;  3CBO A;  3TG5 A;  3CBM A;  3M58 A;  4FMU A;  4NVQ A;  1XQH A;  3RIB A;  4E47 A;  2BQZ A;  5JHN A;  3VV0 A;  2W5Y A;  4IJ8 A;  1PEG A;  2IGQ A;  3M54 A;  5CPR B;  4LDG A;  4RZ0 A;  3RJW A;  4JLG A;  4YNM A;  5F6K C;  3SW9 A;  4BUP A;  5EX0 A;  3OXG A;  1ZKK A;  4Z4P A;  4MI5 A;  2F69 A;  5EG2 A;  3CBP A;  2O8J A;  5F59 A;  3S7J A;  4QEP A;  3F9X A;  5CCL A;  3M53 A;  5JIN A;  3F9Z A;  3OPE A; 
#chains in the Genus database with same CATH homology
 3F9Y A;  1ML9 A;  3RAY A;  5T0M A;  4AU7 A;  3DAL A;  4C1Q A;  4J7I A;  5JJ0 A;  5KJM A;  5KJK A;  3M5A A;  4QEN A;  3F9W A;  5KJN A;  1MT6 A;  4J7F A;  2JV0 A;  3SWC A;  1N6A A;  1O9S A;  3RQ4 A;  3KMA A;  5T5G A;  3MO5 A;  5TH7 A;  3M57 A;  3QWV A;  5F6L A;  1N6C A;  4QEO A;  3S7F A;  5LSZ A;  3OXF A;  4J8O A;  3M55 A;  2RFI A;  3VUZ A;  3BO5 A;  3KMT A;  5F5E A;  3MO0 A;  4I51 A;  4YPU A;  4O30 A;  3MEK A;  3FPD A;  3S7B A;  1H3I A;  4NJ5 A;  4YPA A;  4O6F A;  1MVX A;  4YPE A;  3IHX A;  3KMJ A;  4J83 A;  5LSX A;  3M59 A;  4IJD A;  1MVH A;  3EP0 A;  5CCM A;  5KJL A;  2G46 A;  5AYF A;  3M56 A;  5HQ8 A;  2W5Z A;  3MO2 A;  5ARG A;  3N71 A;  5JIY A;  3S7D A;  3HNA A;  3QWW A;  3OOI A;  5ARF A;  3K5K A;  4JDS A;  3TG4 A;  4YND A;  5HI7 A;  4WUY A;  4MI0 A;  3DB5 A;  3PDN A;  2QPW A;  1MUF A;  3RU0 A;  1N3J A;  3OXL A;  5EX3 A;  5TTF A;  4YNP A;  5TEG A;  4H12 A;  3QWP A;  3OS5 A;  3S8P A;  5T0K A;  2R3A A;  3CBO A;  3TG5 A;  3CBM A;  3M58 A;  4FMU A;  4NVQ A;  1XQH A;  3RIB A;  4E47 A;  2BQZ A;  5JHN A;  3VV0 A;  2W5Y A;  4IJ8 A;  1PEG A;  2IGQ A;  3M54 A;  5CPR B;  4LDG A;  4RZ0 A;  3RJW A;  4JLG A;  4YNM A;  5F6K C;  3SW9 A;  4BUP A;  5EX0 A;  3OXG A;  1ZKK A;  4Z4P A;  4MI5 A;  2F69 A;  5EG2 A;  3CBP A;  2O8J A;  5F59 A;  3S7J A;  4QEP A;  3F9X A;  5CCL A;  3M53 A;  5JIN A;  3F9Z A;  3OPE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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