1N6CA

Structure of set7/9
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
285
structure length
283
Chain Sequence
GGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYSPPGKSGPEAPEWYQVELKAFQAT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords SET domain-containing protein 7
publication title Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet
pubmed doi rcsb
source organism Homo sapiens
total genus 64
structure length 283
sequence length 285
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF02493 MORN MORN repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.110.10 Mainly Beta Single Sheet Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 1n6cA01
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1n6cA02
2R3AA 4JLGA 4IJDA 2G46A 3N71A 1XQHA 4AU7A 4RZ0A 5JINA 5LSXA 3S7FA 5F6KC 2O8JA 4J7FA 3M54A 5HI7A 4IJ8A 5EX3A 4QEPA 4JDSA 5CPRB 4C1QA 4NVQA 5JIYA 5HQ8A 3KMJA 1MVHA 5CCMA 3OXGA 5TTFA 5KJLA 5T5GA 3F9XA 3RU0A 4MI5A 4E47A 3PDNA 4J83A 3QWWA 1MVXA 5JJ0A 2QPWA 3TG5A 1H3IA 3M53A 3F9YA 5F5EA 5F6LA 3S7DA 2JV0A 5CCLA 3FPDA 1ZKKA 3CBMA 4J8OA 5EG2A 4J7IA 4I51A 4YNMA 3RAYA 3BO5A 4BUPA 5TEGA 5T0KA 3MO2A 1N6CA 3S8PA 3M57A 4YPEA 5ARGA 3M5AA 4YPAA 4H12A 1N6AA 4WUYA 5F59A 3HNAA 4O6FA 3OS5A 4O30A 3K5KA 3F9WA 5KJKA 4YPUA 4QEOA 3OXLA 3OXFA 3VV0A 5KJMA 3KMAA 3MO0A 3RJWA 1N3JA 4MI0A 3VUZA 3RIBA 5LSZA 3SWCA 2W5ZA 3MO5A 4QENA 2RFIA 3MEKA 3TG4A 3IHXA 1PEGA 4YNDA 3S7BA 5JHNA 1MUFA 3SW9A 3DALA 3OPEA 2W5YA 3KMTA 3S7JA 5AYFA 3M58A 3M59A 5EX0A 4Z4PA 5TH7A 2BQZA 3QWPA 1ML9A 5T0MA 3OOIA 1O9SA 2F69A 3DB5A 3EP0A 3QWVA 3CBPA 3RQ4A 4LDGA 5ARFA 3M55A 2IGQA 5KJNA 3F9ZA 3M56A 4FMUA 4YNPA 1MT6A 4NJ5A 3CBOA
chains in the Genus database with same CATH superfamily
2R3AA 4JLGA 4IJDA 2G46A 3N71A 1XQHA 4AU7A 4RZ0A 5JINA 5LSXA 3S7FA 5F6KC 2O8JA 4J7FA 3M54A 5HI7A 4IJ8A 5EX3A 4QEPA 4JDSA 5CPRB 4C1QA 4NVQA 5JIYA 5HQ8A 3KMJA 1MVHA 5CCMA 3OXGA 5TTFA 5KJLA 5T5GA 3F9XA 3RU0A 4MI5A 4E47A 3PDNA 4J83A 3QWWA 1MVXA 5JJ0A 2QPWA 3TG5A 1H3IA 3M53A 3F9YA 5F5EA 5F6LA 3S7DA 2JV0A 5CCLA 3FPDA 1ZKKA 3CBMA 4J8OA 5EG2A 4J7IA 4I51A 4YNMA 3RAYA 3BO5A 4BUPA 5TEGA 5T0KA 3MO2A 1N6CA 3S8PA 3M57A 4YPEA 5ARGA 3M5AA 4YPAA 4H12A 1N6AA 4WUYA 5F59A 3HNAA 4O6FA 3OS5A 4O30A 3K5KA 3F9WA 5KJKA 4YPUA 4QEOA 3OXLA 3OXFA 3VV0A 5KJMA 3KMAA 3MO0A 3RJWA 1N3JA 4MI0A 3VUZA 3RIBA 5LSZA 3SWCA 2W5ZA 3MO5A 4QENA 2RFIA 3MEKA 3TG4A 3IHXA 1PEGA 4YNDA 3S7BA 5JHNA 1MUFA 3SW9A 3DALA 3OPEA 2W5YA 3KMTA 3S7JA 5AYFA 3M58A 3M59A 5EX0A 4Z4PA 5TH7A 2BQZA 3QWPA 1ML9A 5T0MA 3OOIA 1O9SA 2F69A 3DB5A 3EP0A 3QWVA 3CBPA 3RQ4A 4LDGA 5ARFA 3M55A 2IGQA 5KJNA 3F9ZA 3M56A 4FMUA 4YNPA 1MT6A 4NJ5A 3CBOA
chains in the Genus database with same CATH topology
2R3AA 4JLGA 4IJDA 2G46A 3N71A 1XQHA 4AU7A 4RZ0A 5JINA 5LSXA 3S7FA 5F6KC 2O8JA 4J7FA 3M54A 5HI7A 4IJ8A 5EX3A 4QEPA 4JDSA 5CPRB 4C1QA 4NVQA 5JIYA 5HQ8A 3KMJA 1MVHA 5CCMA 3OXGA 5TTFA 5KJLA 5T5GA 3F9XA 3RU0A 4MI5A 4E47A 3PDNA 4J83A 3QWWA 1MVXA 5JJ0A 2QPWA 3TG5A 1H3IA 3M53A 3F9YA 5F5EA 5F6LA 3S7DA 2JV0A 5CCLA 3FPDA 1ZKKA 3CBMA 4J8OA 5EG2A 4J7IA 4I51A 4YNMA 3RAYA 3BO5A 4BUPA 5TEGA 5T0KA 3MO2A 1N6CA 3S8PA 3M57A 4YPEA 5ARGA 3M5AA 4YPAA 4H12A 1N6AA 4WUYA 5F59A 3HNAA 4O6FA 3OS5A 4O30A 3K5KA 3F9WA 5KJKA 4YPUA 4QEOA 3OXLA 3OXFA 3VV0A 5KJMA 3KMAA 3MO0A 3RJWA 1N3JA 4MI0A 3VUZA 3RIBA 5LSZA 3SWCA 2W5ZA 3MO5A 4QENA 2RFIA 3MEKA 3TG4A 3IHXA 1PEGA 4YNDA 3S7BA 5JHNA 1MUFA 3SW9A 3DALA 3OPEA 2W5YA 3KMTA 3S7JA 5AYFA 3M58A 3M59A 5EX0A 4Z4PA 5TH7A 2BQZA 3QWPA 1ML9A 5T0MA 3OOIA 1O9SA 2F69A 3DB5A 3EP0A 3QWVA 3CBPA 3RQ4A 4LDGA 5ARFA 3M55A 2IGQA 5KJNA 3F9ZA 3M56A 4FMUA 4YNPA 1MT6A 4NJ5A 3CBOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R3A A;  4JLG A;  4IJD A;  2G46 A;  3N71 A;  1XQH A;  4AU7 A;  4RZ0 A;  5JIN A;  5LSX A;  3S7F A;  5F6K C;  2O8J A;  4J7F A;  3M54 A;  5HI7 A;  4IJ8 A;  5EX3 A;  4QEP A;  4JDS A;  5CPR B;  4C1Q A;  4NVQ A;  5JIY A;  5HQ8 A;  3KMJ A;  1MVH A;  5CCM A;  3OXG A;  5TTF A;  5KJL A;  5T5G A;  3F9X A;  3RU0 A;  4MI5 A;  4E47 A;  3PDN A;  4J83 A;  3QWW A;  1MVX A;  5JJ0 A;  2QPW A;  3TG5 A;  1H3I A;  3M53 A;  3F9Y A;  5F5E A;  5F6L A;  3S7D A;  2JV0 A;  5CCL A;  3FPD A;  1ZKK A;  3CBM A;  4J8O A;  5EG2 A;  4J7I A;  4I51 A;  4YNM A;  3RAY A;  3BO5 A;  4BUP A;  5TEG A;  5T0K A;  3MO2 A;  1N6C A;  3S8P A;  3M57 A;  4YPE A;  5ARG A;  3M5A A;  4YPA A;  4H12 A;  1N6A A;  4WUY A;  5F59 A;  3HNA A;  4O6F A;  3OS5 A;  4O30 A;  3K5K A;  3F9W A;  5KJK A;  4YPU A;  4QEO A;  3OXL A;  3OXF A;  3VV0 A;  5KJM A;  3KMA A;  3MO0 A;  3RJW A;  1N3J A;  4MI0 A;  3VUZ A;  3RIB A;  5LSZ A;  3SWC A;  2W5Z A;  3MO5 A;  4QEN A;  2RFI A;  3MEK A;  3TG4 A;  3IHX A;  1PEG A;  4YND A;  3S7B A;  5JHN A;  1MUF A;  3SW9 A;  3DAL A;  3OPE A;  2W5Y A;  3KMT A;  3S7J A;  5AYF A;  3M58 A;  3M59 A;  5EX0 A;  4Z4P A;  5TH7 A;  2BQZ A;  3QWP A;  1ML9 A;  5T0M A;  3OOI A;  1O9S A;  2F69 A;  3DB5 A;  3EP0 A;  3QWV A;  3CBP A;  3RQ4 A;  4LDG A;  5ARF A;  3M55 A;  2IGQ A;  5KJN A;  3F9Z A;  3M56 A;  4FMU A;  4YNP A;  1MT6 A;  4NJ5 A;  3CBO A; 
#chains in the Genus database with same CATH topology
 2R3A A;  4JLG A;  4IJD A;  2G46 A;  3N71 A;  1XQH A;  4AU7 A;  4RZ0 A;  5JIN A;  5LSX A;  3S7F A;  5F6K C;  2O8J A;  4J7F A;  3M54 A;  5HI7 A;  4IJ8 A;  5EX3 A;  4QEP A;  4JDS A;  5CPR B;  4C1Q A;  4NVQ A;  5JIY A;  5HQ8 A;  3KMJ A;  1MVH A;  5CCM A;  3OXG A;  5TTF A;  5KJL A;  5T5G A;  3F9X A;  3RU0 A;  4MI5 A;  4E47 A;  3PDN A;  4J83 A;  3QWW A;  1MVX A;  5JJ0 A;  2QPW A;  3TG5 A;  1H3I A;  3M53 A;  3F9Y A;  5F5E A;  5F6L A;  3S7D A;  2JV0 A;  5CCL A;  3FPD A;  1ZKK A;  3CBM A;  4J8O A;  5EG2 A;  4J7I A;  4I51 A;  4YNM A;  3RAY A;  3BO5 A;  4BUP A;  5TEG A;  5T0K A;  3MO2 A;  1N6C A;  3S8P A;  3M57 A;  4YPE A;  5ARG A;  3M5A A;  4YPA A;  4H12 A;  1N6A A;  4WUY A;  5F59 A;  3HNA A;  4O6F A;  3OS5 A;  4O30 A;  3K5K A;  3F9W A;  5KJK A;  4YPU A;  4QEO A;  3OXL A;  3OXF A;  3VV0 A;  5KJM A;  3KMA A;  3MO0 A;  3RJW A;  1N3J A;  4MI0 A;  3VUZ A;  3RIB A;  5LSZ A;  3SWC A;  2W5Z A;  3MO5 A;  4QEN A;  2RFI A;  3MEK A;  3TG4 A;  3IHX A;  1PEG A;  4YND A;  3S7B A;  5JHN A;  1MUF A;  3SW9 A;  3DAL A;  3OPE A;  2W5Y A;  3KMT A;  3S7J A;  5AYF A;  3M58 A;  3M59 A;  5EX0 A;  4Z4P A;  5TH7 A;  2BQZ A;  3QWP A;  1ML9 A;  5T0M A;  3OOI A;  1O9S A;  2F69 A;  3DB5 A;  3EP0 A;  3QWV A;  3CBP A;  3RQ4 A;  4LDG A;  5ARF A;  3M55 A;  2IGQ A;  5KJN A;  3F9Z A;  3M56 A;  4FMU A;  4YNP A;  1MT6 A;  4NJ5 A;  3CBO A; 
#chains in the Genus database with same CATH homology
 2R3A A;  4JLG A;  4IJD A;  2G46 A;  3N71 A;  1XQH A;  4AU7 A;  4RZ0 A;  5JIN A;  5LSX A;  3S7F A;  5F6K C;  2O8J A;  4J7F A;  3M54 A;  5HI7 A;  4IJ8 A;  5EX3 A;  4QEP A;  4JDS A;  5CPR B;  4C1Q A;  4NVQ A;  5JIY A;  5HQ8 A;  3KMJ A;  1MVH A;  5CCM A;  3OXG A;  5TTF A;  5KJL A;  5T5G A;  3F9X A;  3RU0 A;  4MI5 A;  4E47 A;  3PDN A;  4J83 A;  3QWW A;  1MVX A;  5JJ0 A;  2QPW A;  3TG5 A;  1H3I A;  3M53 A;  3F9Y A;  5F5E A;  5F6L A;  3S7D A;  2JV0 A;  5CCL A;  3FPD A;  1ZKK A;  3CBM A;  4J8O A;  5EG2 A;  4J7I A;  4I51 A;  4YNM A;  3RAY A;  3BO5 A;  4BUP A;  5TEG A;  5T0K A;  3MO2 A;  1N6C A;  3S8P A;  3M57 A;  4YPE A;  5ARG A;  3M5A A;  4YPA A;  4H12 A;  1N6A A;  4WUY A;  5F59 A;  3HNA A;  4O6F A;  3OS5 A;  4O30 A;  3K5K A;  3F9W A;  5KJK A;  4YPU A;  4QEO A;  3OXL A;  3OXF A;  3VV0 A;  5KJM A;  3KMA A;  3MO0 A;  3RJW A;  1N3J A;  4MI0 A;  3VUZ A;  3RIB A;  5LSZ A;  3SWC A;  2W5Z A;  3MO5 A;  4QEN A;  2RFI A;  3MEK A;  3TG4 A;  3IHX A;  1PEG A;  4YND A;  3S7B A;  5JHN A;  1MUF A;  3SW9 A;  3DAL A;  3OPE A;  2W5Y A;  3KMT A;  3S7J A;  5AYF A;  3M58 A;  3M59 A;  5EX0 A;  4Z4P A;  5TH7 A;  2BQZ A;  3QWP A;  1ML9 A;  5T0M A;  3OOI A;  1O9S A;  2F69 A;  3DB5 A;  3EP0 A;  3QWV A;  3CBP A;  3RQ4 A;  4LDG A;  5ARF A;  3M55 A;  2IGQ A;  5KJN A;  3F9Z A;  3M56 A;  4FMU A;  4YNP A;  1MT6 A;  4NJ5 A;  3CBO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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