1N6CA

Structure of set7/9
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
285
structure length
283
Chain Sequence
b'GGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYSPPGKSGPEAPEWYQVELKAFQAT'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords SET domain-containing protein 7
publication title Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 64
structure length 283
sequence length 285
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF02493 MORN MORN repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.110.10 Mainly Beta Single Sheet Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 1n6cA01
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1n6cA02
3M59A 3KMJA 5HQ8A 3S7FA 3PDNA 4O30A 3TG4A 4IJ8A 1N6CA 2R3AA 3MEKA 3RAYA 5CCMA 5KJLA 4J7IA 5KJMA 3BO5A 3M5AA 1ML9A 4E47A 3TG5A 3DB5A 5JINA 2IGQA 1PEGA 5AYFA 4J83A 5JJ0A 3MO5A 4FMUA 3F9YA 5CPRB 3S7JA 3OXGA 2QPWA 3EP0A 5F5EA 4MI5A 5T5GA 1ZKKA 5HI7A 3RU0A 3MO2A 4MI0A 2JV0A 5ARGA 1O9SA 1XQHA 4J8OA 5EX0A 2W5YA 5TEGA 5JHNA 2O8JA 3OXFA 3RQ4A 2BQZA 4J7FA 3IHXA 2RFIA 4LDGA 4BUPA 4YPEA 3M53A 4NJ5A 4JDSA 5ARFA 4YPAA 5EG2A 3OXLA 5CCLA 3DALA 3S8PA 2F69A 5EX3A 2G46A 5F59A 4H12A 1MUFA 4RZ0A 3FPDA 3OPEA 4QEPA 2W5ZA 4WUYA 3M57A 4IJDA 3F9XA 4I51A 4YNDA 3N71A 5TTFA 4YNPA 3SW9A 1MT6A 1MVXA 4YPUA 3VUZA 3OS5A 4QEOA 4YNMA 5LSZA 5KJKA 3S7DA 3CBOA 5TH7A 3QWVA 3SWCA 4O6FA 4Z4PA 3CBPA 3F9WA 3M55A 3M56A 3S7BA 3OOIA 3QWWA 3KMTA 4NVQA 5F6KC 3M54A 3CBMA 1MVHA 3RIBA 4QENA 4AU7A 3K5KA 1N6AA 4C1QA 3M58A 5KJNA 5F6LA 4JLGA 5T0KA 3KMAA 3HNAA 5JIYA 1N3JA 5LSXA 3MO0A 3QWPA 3VV0A 3F9ZA 3RJWA 5T0MA 1H3IA
chains in the Genus database with same CATH superfamily
3M59A 3KMJA 5HQ8A 3S7FA 3PDNA 4O30A 3TG4A 4IJ8A 1N6CA 2R3AA 3MEKA 3RAYA 5CCMA 5KJLA 4J7IA 5KJMA 3BO5A 3M5AA 1ML9A 4E47A 3TG5A 3DB5A 5JINA 2IGQA 1PEGA 5AYFA 4J83A 5JJ0A 3MO5A 4FMUA 3F9YA 5CPRB 3S7JA 3OXGA 2QPWA 3EP0A 5F5EA 4MI5A 5T5GA 1ZKKA 5HI7A 3RU0A 3MO2A 4MI0A 2JV0A 5ARGA 1O9SA 1XQHA 4J8OA 5EX0A 2W5YA 5TEGA 5JHNA 2O8JA 3OXFA 3RQ4A 2BQZA 4J7FA 3IHXA 2RFIA 4LDGA 4BUPA 4YPEA 3M53A 4NJ5A 4JDSA 5ARFA 4YPAA 5EG2A 3OXLA 5CCLA 3DALA 3S8PA 2F69A 5EX3A 2G46A 5F59A 4H12A 1MUFA 4RZ0A 3FPDA 3OPEA 4QEPA 2W5ZA 4WUYA 3M57A 4IJDA 3F9XA 4I51A 4YNDA 3N71A 5TTFA 4YNPA 3SW9A 1MT6A 1MVXA 4YPUA 3VUZA 3OS5A 4QEOA 4YNMA 5LSZA 5KJKA 3S7DA 3CBOA 5TH7A 3QWVA 3SWCA 4O6FA 4Z4PA 3CBPA 3F9WA 3M55A 3M56A 3S7BA 3OOIA 3QWWA 3KMTA 4NVQA 5F6KC 3M54A 3CBMA 1MVHA 3RIBA 4QENA 4AU7A 3K5KA 1N6AA 4C1QA 3M58A 5KJNA 5F6LA 4JLGA 5T0KA 3KMAA 3HNAA 5JIYA 1N3JA 5LSXA 3MO0A 3QWPA 3VV0A 3F9ZA 3RJWA 5T0MA 1H3IA
chains in the Genus database with same CATH topology
3M59A 3KMJA 5HQ8A 3S7FA 3PDNA 4O30A 3TG4A 4IJ8A 1N6CA 2R3AA 3MEKA 3RAYA 5CCMA 5KJLA 4J7IA 5KJMA 3BO5A 3M5AA 1ML9A 4E47A 3TG5A 3DB5A 5JINA 2IGQA 1PEGA 5AYFA 4J83A 5JJ0A 3MO5A 4FMUA 3F9YA 5CPRB 3S7JA 3OXGA 2QPWA 3EP0A 5F5EA 4MI5A 5T5GA 1ZKKA 5HI7A 3RU0A 3MO2A 4MI0A 2JV0A 5ARGA 1O9SA 1XQHA 4J8OA 5EX0A 2W5YA 5TEGA 5JHNA 2O8JA 3OXFA 3RQ4A 2BQZA 4J7FA 3IHXA 2RFIA 4LDGA 4BUPA 4YPEA 3M53A 4NJ5A 4JDSA 5ARFA 4YPAA 5EG2A 3OXLA 5CCLA 3DALA 3S8PA 2F69A 5EX3A 2G46A 5F59A 4H12A 1MUFA 4RZ0A 3FPDA 3OPEA 4QEPA 2W5ZA 4WUYA 3M57A 4IJDA 3F9XA 4I51A 4YNDA 3N71A 5TTFA 4YNPA 3SW9A 1MT6A 1MVXA 4YPUA 3VUZA 3OS5A 4QEOA 4YNMA 5LSZA 5KJKA 3S7DA 3CBOA 5TH7A 3QWVA 3SWCA 4O6FA 4Z4PA 3CBPA 3F9WA 3M55A 3M56A 3S7BA 3OOIA 3QWWA 3KMTA 4NVQA 5F6KC 3M54A 3CBMA 1MVHA 3RIBA 4QENA 4AU7A 3K5KA 1N6AA 4C1QA 3M58A 5KJNA 5F6LA 4JLGA 5T0KA 3KMAA 3HNAA 5JIYA 1N3JA 5LSXA 3MO0A 3QWPA 3VV0A 3F9ZA 3RJWA 5T0MA 1H3IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M59 A;  3KMJ A;  5HQ8 A;  3S7F A;  3PDN A;  4O30 A;  3TG4 A;  4IJ8 A;  1N6C A;  2R3A A;  3MEK A;  3RAY A;  5CCM A;  5KJL A;  4J7I A;  5KJM A;  3BO5 A;  3M5A A;  1ML9 A;  4E47 A;  3TG5 A;  3DB5 A;  5JIN A;  2IGQ A;  1PEG A;  5AYF A;  4J83 A;  5JJ0 A;  3MO5 A;  4FMU A;  3F9Y A;  5CPR B;  3S7J A;  3OXG A;  2QPW A;  3EP0 A;  5F5E A;  4MI5 A;  5T5G A;  1ZKK A;  5HI7 A;  3RU0 A;  3MO2 A;  4MI0 A;  2JV0 A;  5ARG A;  1O9S A;  1XQH A;  4J8O A;  5EX0 A;  2W5Y A;  5TEG A;  5JHN A;  2O8J A;  3OXF A;  3RQ4 A;  2BQZ A;  4J7F A;  3IHX A;  2RFI A;  4LDG A;  4BUP A;  4YPE A;  3M53 A;  4NJ5 A;  4JDS A;  5ARF A;  4YPA A;  5EG2 A;  3OXL A;  5CCL A;  3DAL A;  3S8P A;  2F69 A;  5EX3 A;  2G46 A;  5F59 A;  4H12 A;  1MUF A;  4RZ0 A;  3FPD A;  3OPE A;  4QEP A;  2W5Z A;  4WUY A;  3M57 A;  4IJD A;  3F9X A;  4I51 A;  4YND A;  3N71 A;  5TTF A;  4YNP A;  3SW9 A;  1MT6 A;  1MVX A;  4YPU A;  3VUZ A;  3OS5 A;  4QEO A;  4YNM A;  5LSZ A;  5KJK A;  3S7D A;  3CBO A;  5TH7 A;  3QWV A;  3SWC A;  4O6F A;  4Z4P A;  3CBP A;  3F9W A;  3M55 A;  3M56 A;  3S7B A;  3OOI A;  3QWW A;  3KMT A;  4NVQ A;  5F6K C;  3M54 A;  3CBM A;  1MVH A;  3RIB A;  4QEN A;  4AU7 A;  3K5K A;  1N6A A;  4C1Q A;  3M58 A;  5KJN A;  5F6L A;  4JLG A;  5T0K A;  3KMA A;  3HNA A;  5JIY A;  1N3J A;  5LSX A;  3MO0 A;  3QWP A;  3VV0 A;  3F9Z A;  3RJW A;  5T0M A;  1H3I A; 
#chains in the Genus database with same CATH topology
 3M59 A;  3KMJ A;  5HQ8 A;  3S7F A;  3PDN A;  4O30 A;  3TG4 A;  4IJ8 A;  1N6C A;  2R3A A;  3MEK A;  3RAY A;  5CCM A;  5KJL A;  4J7I A;  5KJM A;  3BO5 A;  3M5A A;  1ML9 A;  4E47 A;  3TG5 A;  3DB5 A;  5JIN A;  2IGQ A;  1PEG A;  5AYF A;  4J83 A;  5JJ0 A;  3MO5 A;  4FMU A;  3F9Y A;  5CPR B;  3S7J A;  3OXG A;  2QPW A;  3EP0 A;  5F5E A;  4MI5 A;  5T5G A;  1ZKK A;  5HI7 A;  3RU0 A;  3MO2 A;  4MI0 A;  2JV0 A;  5ARG A;  1O9S A;  1XQH A;  4J8O A;  5EX0 A;  2W5Y A;  5TEG A;  5JHN A;  2O8J A;  3OXF A;  3RQ4 A;  2BQZ A;  4J7F A;  3IHX A;  2RFI A;  4LDG A;  4BUP A;  4YPE A;  3M53 A;  4NJ5 A;  4JDS A;  5ARF A;  4YPA A;  5EG2 A;  3OXL A;  5CCL A;  3DAL A;  3S8P A;  2F69 A;  5EX3 A;  2G46 A;  5F59 A;  4H12 A;  1MUF A;  4RZ0 A;  3FPD A;  3OPE A;  4QEP A;  2W5Z A;  4WUY A;  3M57 A;  4IJD A;  3F9X A;  4I51 A;  4YND A;  3N71 A;  5TTF A;  4YNP A;  3SW9 A;  1MT6 A;  1MVX A;  4YPU A;  3VUZ A;  3OS5 A;  4QEO A;  4YNM A;  5LSZ A;  5KJK A;  3S7D A;  3CBO A;  5TH7 A;  3QWV A;  3SWC A;  4O6F A;  4Z4P A;  3CBP A;  3F9W A;  3M55 A;  3M56 A;  3S7B A;  3OOI A;  3QWW A;  3KMT A;  4NVQ A;  5F6K C;  3M54 A;  3CBM A;  1MVH A;  3RIB A;  4QEN A;  4AU7 A;  3K5K A;  1N6A A;  4C1Q A;  3M58 A;  5KJN A;  5F6L A;  4JLG A;  5T0K A;  3KMA A;  3HNA A;  5JIY A;  1N3J A;  5LSX A;  3MO0 A;  3QWP A;  3VV0 A;  3F9Z A;  3RJW A;  5T0M A;  1H3I A; 
#chains in the Genus database with same CATH homology
 3M59 A;  3KMJ A;  5HQ8 A;  3S7F A;  3PDN A;  4O30 A;  3TG4 A;  4IJ8 A;  1N6C A;  2R3A A;  3MEK A;  3RAY A;  5CCM A;  5KJL A;  4J7I A;  5KJM A;  3BO5 A;  3M5A A;  1ML9 A;  4E47 A;  3TG5 A;  3DB5 A;  5JIN A;  2IGQ A;  1PEG A;  5AYF A;  4J83 A;  5JJ0 A;  3MO5 A;  4FMU A;  3F9Y A;  5CPR B;  3S7J A;  3OXG A;  2QPW A;  3EP0 A;  5F5E A;  4MI5 A;  5T5G A;  1ZKK A;  5HI7 A;  3RU0 A;  3MO2 A;  4MI0 A;  2JV0 A;  5ARG A;  1O9S A;  1XQH A;  4J8O A;  5EX0 A;  2W5Y A;  5TEG A;  5JHN A;  2O8J A;  3OXF A;  3RQ4 A;  2BQZ A;  4J7F A;  3IHX A;  2RFI A;  4LDG A;  4BUP A;  4YPE A;  3M53 A;  4NJ5 A;  4JDS A;  5ARF A;  4YPA A;  5EG2 A;  3OXL A;  5CCL A;  3DAL A;  3S8P A;  2F69 A;  5EX3 A;  2G46 A;  5F59 A;  4H12 A;  1MUF A;  4RZ0 A;  3FPD A;  3OPE A;  4QEP A;  2W5Z A;  4WUY A;  3M57 A;  4IJD A;  3F9X A;  4I51 A;  4YND A;  3N71 A;  5TTF A;  4YNP A;  3SW9 A;  1MT6 A;  1MVX A;  4YPU A;  3VUZ A;  3OS5 A;  4QEO A;  4YNM A;  5LSZ A;  5KJK A;  3S7D A;  3CBO A;  5TH7 A;  3QWV A;  3SWC A;  4O6F A;  4Z4P A;  3CBP A;  3F9W A;  3M55 A;  3M56 A;  3S7B A;  3OOI A;  3QWW A;  3KMT A;  4NVQ A;  5F6K C;  3M54 A;  3CBM A;  1MVH A;  3RIB A;  4QEN A;  4AU7 A;  3K5K A;  1N6A A;  4C1Q A;  3M58 A;  5KJN A;  5F6L A;  4JLG A;  5T0K A;  3KMA A;  3HNA A;  5JIY A;  1N3J A;  5LSX A;  3MO0 A;  3QWP A;  3VV0 A;  3F9Z A;  3RJW A;  5T0M A;  1H3I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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