2O8JA

Human euchromatic histone methyltransferase 2
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
262
structure length
254
Chain Sequence
b'KIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDYFTCQCGSEKCKHSAEA'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Histone-lysine N-methyltransferase, H3 lysine-9 specific 3
publication title Structural biology of human H3K9 methyltransferases
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 59
structure length 254
sequence length 262
chains with identical sequence B, C, D
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2006-12-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 2o8jA00
3OPEA 2F69A 3S7FA 4I51A 3M54A 4J8OA 3SWCA 3MO0A 3M55A 5EX0A 5ARFA 3SW9A 5HI7A 5ARGA 5KJNA 3S7DA 3MO5A 3EP0A 3OXGA 4YNMA 5KJLA 3F9XA 5TEGA 3F9ZA 4Z4PA 4QEPA 5JJ0A 5F5EA 3F9WA 3M57A 4NVQA 4NJ5A 4YNDA 2W5ZA 4H12A 3RU0A 2G46A 4O30A 3TG4A 2IGQA 4FMUA 4MI0A 5HQ8A 4J83A 5CPRB 5CCLA 3HNAA 1O9SA 3OXLA 5F59A 1ZKKA 5T5GA 2R3AA 3IHXA 5KJKA 5JINA 5CCMA 3RJWA 3K5KA 2W5YA 2O8JA 4JDSA 3FPDA 4QENA 3VV0A 3CBPA 1N3JA 1ML9A 3M53A 3RQ4A 4YPAA 4J7IA 5LSXA 5KJMA 1PEGA 3VUZA 3BO5A 4YPEA 3CBOA 4BUPA 1N6AA 2RFIA 3OXFA 4QEOA 3S8PA 1XQHA 5EG2A 5F6KC 3RAYA 4MI5A 4IJ8A 4AU7A 5TTFA 3M59A 3OS5A 4E47A 4O6FA 1H3IA 3CBMA 2BQZA 3S7JA 3KMJA 4WUYA 3S7BA 4IJDA 3PDNA 4C1QA 1MUFA 4YNPA 5AYFA 3QWVA 3N71A 4YPUA 5JIYA 5TH7A 3OOIA 4LDGA 3M5AA 2JV0A 3TG5A 5F6LA 5EX3A 5T0MA 3RIBA 1MVXA 3MO2A 3MEKA 2QPWA 1MVHA 3M58A 1MT6A 4JLGA 3QWWA 3DALA 1N6CA 5T0KA 4RZ0A 5LSZA 3KMTA 3QWPA 3M56A 3KMAA 5JHNA 3F9YA 4J7FA 3DB5A
chains in the Genus database with same CATH superfamily
3OPEA 2F69A 3S7FA 4I51A 3M54A 4J8OA 3SWCA 3MO0A 3M55A 5EX0A 5ARFA 3SW9A 5HI7A 5ARGA 5KJNA 3S7DA 3MO5A 3EP0A 3OXGA 4YNMA 5KJLA 3F9XA 5TEGA 3F9ZA 4Z4PA 4QEPA 5JJ0A 5F5EA 3F9WA 3M57A 4NVQA 4NJ5A 4YNDA 2W5ZA 4H12A 3RU0A 2G46A 4O30A 3TG4A 2IGQA 4FMUA 4MI0A 5HQ8A 4J83A 5CPRB 5CCLA 3HNAA 1O9SA 3OXLA 5F59A 1ZKKA 5T5GA 2R3AA 3IHXA 5KJKA 5JINA 5CCMA 3RJWA 3K5KA 2W5YA 2O8JA 4JDSA 3FPDA 4QENA 3VV0A 3CBPA 1N3JA 1ML9A 3M53A 3RQ4A 4YPAA 4J7IA 5LSXA 5KJMA 1PEGA 3VUZA 3BO5A 4YPEA 3CBOA 4BUPA 1N6AA 2RFIA 3OXFA 4QEOA 3S8PA 1XQHA 5EG2A 5F6KC 3RAYA 4MI5A 4IJ8A 4AU7A 5TTFA 3M59A 3OS5A 4E47A 4O6FA 1H3IA 3CBMA 2BQZA 3S7JA 3KMJA 4WUYA 3S7BA 4IJDA 3PDNA 4C1QA 1MUFA 4YNPA 5AYFA 3QWVA 3N71A 4YPUA 5JIYA 5TH7A 3OOIA 4LDGA 3M5AA 2JV0A 3TG5A 5F6LA 5EX3A 5T0MA 3RIBA 1MVXA 3MO2A 3MEKA 2QPWA 1MVHA 3M58A 1MT6A 4JLGA 3QWWA 3DALA 1N6CA 5T0KA 4RZ0A 5LSZA 3KMTA 3QWPA 3M56A 3KMAA 5JHNA 3F9YA 4J7FA 3DB5A
chains in the Genus database with same CATH topology
3OPEA 2F69A 3S7FA 4I51A 3M54A 4J8OA 3SWCA 3MO0A 3M55A 5EX0A 5ARFA 3SW9A 5HI7A 5ARGA 5KJNA 3S7DA 3MO5A 3EP0A 3OXGA 4YNMA 5KJLA 3F9XA 5TEGA 3F9ZA 4Z4PA 4QEPA 5JJ0A 5F5EA 3F9WA 3M57A 4NVQA 4NJ5A 4YNDA 2W5ZA 4H12A 3RU0A 2G46A 4O30A 3TG4A 2IGQA 4FMUA 4MI0A 5HQ8A 4J83A 5CPRB 5CCLA 3HNAA 1O9SA 3OXLA 5F59A 1ZKKA 5T5GA 2R3AA 3IHXA 5KJKA 5JINA 5CCMA 3RJWA 3K5KA 2W5YA 2O8JA 4JDSA 3FPDA 4QENA 3VV0A 3CBPA 1N3JA 1ML9A 3M53A 3RQ4A 4YPAA 4J7IA 5LSXA 5KJMA 1PEGA 3VUZA 3BO5A 4YPEA 3CBOA 4BUPA 1N6AA 2RFIA 3OXFA 4QEOA 3S8PA 1XQHA 5EG2A 5F6KC 3RAYA 4MI5A 4IJ8A 4AU7A 5TTFA 3M59A 3OS5A 4E47A 4O6FA 1H3IA 3CBMA 2BQZA 3S7JA 3KMJA 4WUYA 3S7BA 4IJDA 3PDNA 4C1QA 1MUFA 4YNPA 5AYFA 3QWVA 3N71A 4YPUA 5JIYA 5TH7A 3OOIA 4LDGA 3M5AA 2JV0A 3TG5A 5F6LA 5EX3A 5T0MA 3RIBA 1MVXA 3MO2A 3MEKA 2QPWA 1MVHA 3M58A 1MT6A 4JLGA 3QWWA 3DALA 1N6CA 5T0KA 4RZ0A 5LSZA 3KMTA 3QWPA 3M56A 3KMAA 5JHNA 3F9YA 4J7FA 3DB5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OPE A;  2F69 A;  3S7F A;  4I51 A;  3M54 A;  4J8O A;  3SWC A;  3MO0 A;  3M55 A;  5EX0 A;  5ARF A;  3SW9 A;  5HI7 A;  5ARG A;  5KJN A;  3S7D A;  3MO5 A;  3EP0 A;  3OXG A;  4YNM A;  5KJL A;  3F9X A;  5TEG A;  3F9Z A;  4Z4P A;  4QEP A;  5JJ0 A;  5F5E A;  3F9W A;  3M57 A;  4NVQ A;  4NJ5 A;  4YND A;  2W5Z A;  4H12 A;  3RU0 A;  2G46 A;  4O30 A;  3TG4 A;  2IGQ A;  4FMU A;  4MI0 A;  5HQ8 A;  4J83 A;  5CPR B;  5CCL A;  3HNA A;  1O9S A;  3OXL A;  5F59 A;  1ZKK A;  5T5G A;  2R3A A;  3IHX A;  5KJK A;  5JIN A;  5CCM A;  3RJW A;  3K5K A;  2W5Y A;  2O8J A;  4JDS A;  3FPD A;  4QEN A;  3VV0 A;  3CBP A;  1N3J A;  1ML9 A;  3M53 A;  3RQ4 A;  4YPA A;  4J7I A;  5LSX A;  5KJM A;  1PEG A;  3VUZ A;  3BO5 A;  4YPE A;  3CBO A;  4BUP A;  1N6A A;  2RFI A;  3OXF A;  4QEO A;  3S8P A;  1XQH A;  5EG2 A;  5F6K C;  3RAY A;  4MI5 A;  4IJ8 A;  4AU7 A;  5TTF A;  3M59 A;  3OS5 A;  4E47 A;  4O6F A;  1H3I A;  3CBM A;  2BQZ A;  3S7J A;  3KMJ A;  4WUY A;  3S7B A;  4IJD A;  3PDN A;  4C1Q A;  1MUF A;  4YNP A;  5AYF A;  3QWV A;  3N71 A;  4YPU A;  5JIY A;  5TH7 A;  3OOI A;  4LDG A;  3M5A A;  2JV0 A;  3TG5 A;  5F6L A;  5EX3 A;  5T0M A;  3RIB A;  1MVX A;  3MO2 A;  3MEK A;  2QPW A;  1MVH A;  3M58 A;  1MT6 A;  4JLG A;  3QWW A;  3DAL A;  1N6C A;  5T0K A;  4RZ0 A;  5LSZ A;  3KMT A;  3QWP A;  3M56 A;  3KMA A;  5JHN A;  3F9Y A;  4J7F A;  3DB5 A; 
#chains in the Genus database with same CATH topology
 3OPE A;  2F69 A;  3S7F A;  4I51 A;  3M54 A;  4J8O A;  3SWC A;  3MO0 A;  3M55 A;  5EX0 A;  5ARF A;  3SW9 A;  5HI7 A;  5ARG A;  5KJN A;  3S7D A;  3MO5 A;  3EP0 A;  3OXG A;  4YNM A;  5KJL A;  3F9X A;  5TEG A;  3F9Z A;  4Z4P A;  4QEP A;  5JJ0 A;  5F5E A;  3F9W A;  3M57 A;  4NVQ A;  4NJ5 A;  4YND A;  2W5Z A;  4H12 A;  3RU0 A;  2G46 A;  4O30 A;  3TG4 A;  2IGQ A;  4FMU A;  4MI0 A;  5HQ8 A;  4J83 A;  5CPR B;  5CCL A;  3HNA A;  1O9S A;  3OXL A;  5F59 A;  1ZKK A;  5T5G A;  2R3A A;  3IHX A;  5KJK A;  5JIN A;  5CCM A;  3RJW A;  3K5K A;  2W5Y A;  2O8J A;  4JDS A;  3FPD A;  4QEN A;  3VV0 A;  3CBP A;  1N3J A;  1ML9 A;  3M53 A;  3RQ4 A;  4YPA A;  4J7I A;  5LSX A;  5KJM A;  1PEG A;  3VUZ A;  3BO5 A;  4YPE A;  3CBO A;  4BUP A;  1N6A A;  2RFI A;  3OXF A;  4QEO A;  3S8P A;  1XQH A;  5EG2 A;  5F6K C;  3RAY A;  4MI5 A;  4IJ8 A;  4AU7 A;  5TTF A;  3M59 A;  3OS5 A;  4E47 A;  4O6F A;  1H3I A;  3CBM A;  2BQZ A;  3S7J A;  3KMJ A;  4WUY A;  3S7B A;  4IJD A;  3PDN A;  4C1Q A;  1MUF A;  4YNP A;  5AYF A;  3QWV A;  3N71 A;  4YPU A;  5JIY A;  5TH7 A;  3OOI A;  4LDG A;  3M5A A;  2JV0 A;  3TG5 A;  5F6L A;  5EX3 A;  5T0M A;  3RIB A;  1MVX A;  3MO2 A;  3MEK A;  2QPW A;  1MVH A;  3M58 A;  1MT6 A;  4JLG A;  3QWW A;  3DAL A;  1N6C A;  5T0K A;  4RZ0 A;  5LSZ A;  3KMT A;  3QWP A;  3M56 A;  3KMA A;  5JHN A;  3F9Y A;  4J7F A;  3DB5 A; 
#chains in the Genus database with same CATH homology
 3OPE A;  2F69 A;  3S7F A;  4I51 A;  3M54 A;  4J8O A;  3SWC A;  3MO0 A;  3M55 A;  5EX0 A;  5ARF A;  3SW9 A;  5HI7 A;  5ARG A;  5KJN A;  3S7D A;  3MO5 A;  3EP0 A;  3OXG A;  4YNM A;  5KJL A;  3F9X A;  5TEG A;  3F9Z A;  4Z4P A;  4QEP A;  5JJ0 A;  5F5E A;  3F9W A;  3M57 A;  4NVQ A;  4NJ5 A;  4YND A;  2W5Z A;  4H12 A;  3RU0 A;  2G46 A;  4O30 A;  3TG4 A;  2IGQ A;  4FMU A;  4MI0 A;  5HQ8 A;  4J83 A;  5CPR B;  5CCL A;  3HNA A;  1O9S A;  3OXL A;  5F59 A;  1ZKK A;  5T5G A;  2R3A A;  3IHX A;  5KJK A;  5JIN A;  5CCM A;  3RJW A;  3K5K A;  2W5Y A;  2O8J A;  4JDS A;  3FPD A;  4QEN A;  3VV0 A;  3CBP A;  1N3J A;  1ML9 A;  3M53 A;  3RQ4 A;  4YPA A;  4J7I A;  5LSX A;  5KJM A;  1PEG A;  3VUZ A;  3BO5 A;  4YPE A;  3CBO A;  4BUP A;  1N6A A;  2RFI A;  3OXF A;  4QEO A;  3S8P A;  1XQH A;  5EG2 A;  5F6K C;  3RAY A;  4MI5 A;  4IJ8 A;  4AU7 A;  5TTF A;  3M59 A;  3OS5 A;  4E47 A;  4O6F A;  1H3I A;  3CBM A;  2BQZ A;  3S7J A;  3KMJ A;  4WUY A;  3S7B A;  4IJD A;  3PDN A;  4C1Q A;  1MUF A;  4YNP A;  5AYF A;  3QWV A;  3N71 A;  4YPU A;  5JIY A;  5TH7 A;  3OOI A;  4LDG A;  3M5A A;  2JV0 A;  3TG5 A;  5F6L A;  5EX3 A;  5T0M A;  3RIB A;  1MVX A;  3MO2 A;  3MEK A;  2QPW A;  1MVH A;  3M58 A;  1MT6 A;  4JLG A;  3QWW A;  3DAL A;  1N6C A;  5T0K A;  4RZ0 A;  5LSZ A;  3KMT A;  3QWP A;  3M56 A;  3KMA A;  5JHN A;  3F9Y A;  4J7F A;  3DB5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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