2O8JA

Human euchromatic histone methyltransferase 2
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
262
structure length
254
Chain Sequence
b'KIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDYFTCQCGSEKCKHSAEA'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Histone-lysine N-methyltransferase, H3 lysine-9 specific 3
publication title Structural biology of human H3K9 methyltransferases
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 59
structure length 254
sequence length 262
chains with identical sequence B, C, D
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2006-12-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 2o8jA00
3RAYA 4JDSA 3S7BA 3KMAA 4E47A 3TG5A 5JJ0A 3VUZA 3CBMA 3K5KA 2BQZA 3M5AA 3VV0A 2IGQA 2G46A 5HQ8A 3BO5A 4LDGA 4YNDA 1O9SA 4H12A 1XQHA 4O6FA 4C1QA 5CCMA 4NVQA 5ARGA 1MVHA 2W5ZA 4J7FA 4BUPA 5JINA 3N71A 5CPRB 3CBOA 3KMJA 3F9YA 3MO0A 5JHNA 4Z4PA 3M55A 5LSXA 5T0MA 5F59A 3MO5A 3M56A 3OXLA 3OS5A 5CCLA 1MT6A 3RJWA 3S7JA 1MUFA 5KJMA 4JLGA 4NJ5A 4IJDA 1ZKKA 5TEGA 4J8OA 3KMTA 1N6AA 2R3AA 1ML9A 4WUYA 3M57A 3MO2A 3M53A 5TH7A 4YNPA 1N6CA 3FPDA 3S8PA 4O30A 2F69A 1MVXA 4IJ8A 3EP0A 3QWPA 3DALA 4I51A 3S7DA 3S7FA 3F9WA 3OXFA 1H3IA 4J83A 3SW9A 5F6KC 3QWWA 4YNMA 5EX0A 3HNAA 5LSZA 5F5EA 5T5GA 3SWCA 3M59A 4QEOA 3OPEA 3F9XA 2O8JA 1PEGA 2JV0A 4YPEA 4YPUA 3RIBA 5ARFA 1N3JA 4MI0A 4FMUA 3M54A 5KJLA 3OOIA 5EG2A 3DB5A 4RZ0A 5TTFA 4QEPA 3CBPA 5AYFA 5T0KA 3M58A 3TG4A 5HI7A 3F9ZA 3IHXA 4QENA 2W5YA 4YPAA 5EX3A 5KJNA 5F6LA 4J7IA 3RU0A 3OXGA 4MI5A 3PDNA 4AU7A 5KJKA 5JIYA 3RQ4A 3QWVA 2RFIA 2QPWA 3MEKA
chains in the Genus database with same CATH superfamily
3RAYA 4JDSA 3S7BA 3KMAA 4E47A 3TG5A 5JJ0A 3VUZA 3CBMA 3K5KA 2BQZA 3M5AA 3VV0A 2IGQA 2G46A 5HQ8A 3BO5A 4LDGA 4YNDA 1O9SA 4H12A 1XQHA 4O6FA 4C1QA 5CCMA 4NVQA 5ARGA 1MVHA 2W5ZA 4J7FA 4BUPA 5JINA 3N71A 5CPRB 3CBOA 3KMJA 3F9YA 3MO0A 5JHNA 4Z4PA 3M55A 5LSXA 5T0MA 5F59A 3MO5A 3M56A 3OXLA 3OS5A 5CCLA 1MT6A 3RJWA 3S7JA 1MUFA 5KJMA 4JLGA 4NJ5A 4IJDA 1ZKKA 5TEGA 4J8OA 3KMTA 1N6AA 2R3AA 1ML9A 4WUYA 3M57A 3MO2A 3M53A 5TH7A 4YNPA 1N6CA 3FPDA 3S8PA 4O30A 2F69A 1MVXA 4IJ8A 3EP0A 3QWPA 3DALA 4I51A 3S7DA 3S7FA 3F9WA 3OXFA 1H3IA 4J83A 3SW9A 5F6KC 3QWWA 4YNMA 5EX0A 3HNAA 5LSZA 5F5EA 5T5GA 3SWCA 3M59A 4QEOA 3OPEA 3F9XA 2O8JA 1PEGA 2JV0A 4YPEA 4YPUA 3RIBA 5ARFA 1N3JA 4MI0A 4FMUA 3M54A 5KJLA 3OOIA 5EG2A 3DB5A 4RZ0A 5TTFA 4QEPA 3CBPA 5AYFA 5T0KA 3M58A 3TG4A 5HI7A 3F9ZA 3IHXA 4QENA 2W5YA 4YPAA 5EX3A 5KJNA 5F6LA 4J7IA 3RU0A 3OXGA 4MI5A 3PDNA 4AU7A 5KJKA 5JIYA 3RQ4A 3QWVA 2RFIA 2QPWA 3MEKA
chains in the Genus database with same CATH topology
3RAYA 4JDSA 3S7BA 3KMAA 4E47A 3TG5A 5JJ0A 3VUZA 3CBMA 3K5KA 2BQZA 3M5AA 3VV0A 2IGQA 2G46A 5HQ8A 3BO5A 4LDGA 4YNDA 1O9SA 4H12A 1XQHA 4O6FA 4C1QA 5CCMA 4NVQA 5ARGA 1MVHA 2W5ZA 4J7FA 4BUPA 5JINA 3N71A 5CPRB 3CBOA 3KMJA 3F9YA 3MO0A 5JHNA 4Z4PA 3M55A 5LSXA 5T0MA 5F59A 3MO5A 3M56A 3OXLA 3OS5A 5CCLA 1MT6A 3RJWA 3S7JA 1MUFA 5KJMA 4JLGA 4NJ5A 4IJDA 1ZKKA 5TEGA 4J8OA 3KMTA 1N6AA 2R3AA 1ML9A 4WUYA 3M57A 3MO2A 3M53A 5TH7A 4YNPA 1N6CA 3FPDA 3S8PA 4O30A 2F69A 1MVXA 4IJ8A 3EP0A 3QWPA 3DALA 4I51A 3S7DA 3S7FA 3F9WA 3OXFA 1H3IA 4J83A 3SW9A 5F6KC 3QWWA 4YNMA 5EX0A 3HNAA 5LSZA 5F5EA 5T5GA 3SWCA 3M59A 4QEOA 3OPEA 3F9XA 2O8JA 1PEGA 2JV0A 4YPEA 4YPUA 3RIBA 5ARFA 1N3JA 4MI0A 4FMUA 3M54A 5KJLA 3OOIA 5EG2A 3DB5A 4RZ0A 5TTFA 4QEPA 3CBPA 5AYFA 5T0KA 3M58A 3TG4A 5HI7A 3F9ZA 3IHXA 4QENA 2W5YA 4YPAA 5EX3A 5KJNA 5F6LA 4J7IA 3RU0A 3OXGA 4MI5A 3PDNA 4AU7A 5KJKA 5JIYA 3RQ4A 3QWVA 2RFIA 2QPWA 3MEKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RAY A;  4JDS A;  3S7B A;  3KMA A;  4E47 A;  3TG5 A;  5JJ0 A;  3VUZ A;  3CBM A;  3K5K A;  2BQZ A;  3M5A A;  3VV0 A;  2IGQ A;  2G46 A;  5HQ8 A;  3BO5 A;  4LDG A;  4YND A;  1O9S A;  4H12 A;  1XQH A;  4O6F A;  4C1Q A;  5CCM A;  4NVQ A;  5ARG A;  1MVH A;  2W5Z A;  4J7F A;  4BUP A;  5JIN A;  3N71 A;  5CPR B;  3CBO A;  3KMJ A;  3F9Y A;  3MO0 A;  5JHN A;  4Z4P A;  3M55 A;  5LSX A;  5T0M A;  5F59 A;  3MO5 A;  3M56 A;  3OXL A;  3OS5 A;  5CCL A;  1MT6 A;  3RJW A;  3S7J A;  1MUF A;  5KJM A;  4JLG A;  4NJ5 A;  4IJD A;  1ZKK A;  5TEG A;  4J8O A;  3KMT A;  1N6A A;  2R3A A;  1ML9 A;  4WUY A;  3M57 A;  3MO2 A;  3M53 A;  5TH7 A;  4YNP A;  1N6C A;  3FPD A;  3S8P A;  4O30 A;  2F69 A;  1MVX A;  4IJ8 A;  3EP0 A;  3QWP A;  3DAL A;  4I51 A;  3S7D A;  3S7F A;  3F9W A;  3OXF A;  1H3I A;  4J83 A;  3SW9 A;  5F6K C;  3QWW A;  4YNM A;  5EX0 A;  3HNA A;  5LSZ A;  5F5E A;  5T5G A;  3SWC A;  3M59 A;  4QEO A;  3OPE A;  3F9X A;  2O8J A;  1PEG A;  2JV0 A;  4YPE A;  4YPU A;  3RIB A;  5ARF A;  1N3J A;  4MI0 A;  4FMU A;  3M54 A;  5KJL A;  3OOI A;  5EG2 A;  3DB5 A;  4RZ0 A;  5TTF A;  4QEP A;  3CBP A;  5AYF A;  5T0K A;  3M58 A;  3TG4 A;  5HI7 A;  3F9Z A;  3IHX A;  4QEN A;  2W5Y A;  4YPA A;  5EX3 A;  5KJN A;  5F6L A;  4J7I A;  3RU0 A;  3OXG A;  4MI5 A;  3PDN A;  4AU7 A;  5KJK A;  5JIY A;  3RQ4 A;  3QWV A;  2RFI A;  2QPW A;  3MEK A; 
#chains in the Genus database with same CATH topology
 3RAY A;  4JDS A;  3S7B A;  3KMA A;  4E47 A;  3TG5 A;  5JJ0 A;  3VUZ A;  3CBM A;  3K5K A;  2BQZ A;  3M5A A;  3VV0 A;  2IGQ A;  2G46 A;  5HQ8 A;  3BO5 A;  4LDG A;  4YND A;  1O9S A;  4H12 A;  1XQH A;  4O6F A;  4C1Q A;  5CCM A;  4NVQ A;  5ARG A;  1MVH A;  2W5Z A;  4J7F A;  4BUP A;  5JIN A;  3N71 A;  5CPR B;  3CBO A;  3KMJ A;  3F9Y A;  3MO0 A;  5JHN A;  4Z4P A;  3M55 A;  5LSX A;  5T0M A;  5F59 A;  3MO5 A;  3M56 A;  3OXL A;  3OS5 A;  5CCL A;  1MT6 A;  3RJW A;  3S7J A;  1MUF A;  5KJM A;  4JLG A;  4NJ5 A;  4IJD A;  1ZKK A;  5TEG A;  4J8O A;  3KMT A;  1N6A A;  2R3A A;  1ML9 A;  4WUY A;  3M57 A;  3MO2 A;  3M53 A;  5TH7 A;  4YNP A;  1N6C A;  3FPD A;  3S8P A;  4O30 A;  2F69 A;  1MVX A;  4IJ8 A;  3EP0 A;  3QWP A;  3DAL A;  4I51 A;  3S7D A;  3S7F A;  3F9W A;  3OXF A;  1H3I A;  4J83 A;  3SW9 A;  5F6K C;  3QWW A;  4YNM A;  5EX0 A;  3HNA A;  5LSZ A;  5F5E A;  5T5G A;  3SWC A;  3M59 A;  4QEO A;  3OPE A;  3F9X A;  2O8J A;  1PEG A;  2JV0 A;  4YPE A;  4YPU A;  3RIB A;  5ARF A;  1N3J A;  4MI0 A;  4FMU A;  3M54 A;  5KJL A;  3OOI A;  5EG2 A;  3DB5 A;  4RZ0 A;  5TTF A;  4QEP A;  3CBP A;  5AYF A;  5T0K A;  3M58 A;  3TG4 A;  5HI7 A;  3F9Z A;  3IHX A;  4QEN A;  2W5Y A;  4YPA A;  5EX3 A;  5KJN A;  5F6L A;  4J7I A;  3RU0 A;  3OXG A;  4MI5 A;  3PDN A;  4AU7 A;  5KJK A;  5JIY A;  3RQ4 A;  3QWV A;  2RFI A;  2QPW A;  3MEK A; 
#chains in the Genus database with same CATH homology
 3RAY A;  4JDS A;  3S7B A;  3KMA A;  4E47 A;  3TG5 A;  5JJ0 A;  3VUZ A;  3CBM A;  3K5K A;  2BQZ A;  3M5A A;  3VV0 A;  2IGQ A;  2G46 A;  5HQ8 A;  3BO5 A;  4LDG A;  4YND A;  1O9S A;  4H12 A;  1XQH A;  4O6F A;  4C1Q A;  5CCM A;  4NVQ A;  5ARG A;  1MVH A;  2W5Z A;  4J7F A;  4BUP A;  5JIN A;  3N71 A;  5CPR B;  3CBO A;  3KMJ A;  3F9Y A;  3MO0 A;  5JHN A;  4Z4P A;  3M55 A;  5LSX A;  5T0M A;  5F59 A;  3MO5 A;  3M56 A;  3OXL A;  3OS5 A;  5CCL A;  1MT6 A;  3RJW A;  3S7J A;  1MUF A;  5KJM A;  4JLG A;  4NJ5 A;  4IJD A;  1ZKK A;  5TEG A;  4J8O A;  3KMT A;  1N6A A;  2R3A A;  1ML9 A;  4WUY A;  3M57 A;  3MO2 A;  3M53 A;  5TH7 A;  4YNP A;  1N6C A;  3FPD A;  3S8P A;  4O30 A;  2F69 A;  1MVX A;  4IJ8 A;  3EP0 A;  3QWP A;  3DAL A;  4I51 A;  3S7D A;  3S7F A;  3F9W A;  3OXF A;  1H3I A;  4J83 A;  3SW9 A;  5F6K C;  3QWW A;  4YNM A;  5EX0 A;  3HNA A;  5LSZ A;  5F5E A;  5T5G A;  3SWC A;  3M59 A;  4QEO A;  3OPE A;  3F9X A;  2O8J A;  1PEG A;  2JV0 A;  4YPE A;  4YPU A;  3RIB A;  5ARF A;  1N3J A;  4MI0 A;  4FMU A;  3M54 A;  5KJL A;  3OOI A;  5EG2 A;  3DB5 A;  4RZ0 A;  5TTF A;  4QEP A;  3CBP A;  5AYF A;  5T0K A;  3M58 A;  3TG4 A;  5HI7 A;  3F9Z A;  3IHX A;  4QEN A;  2W5Y A;  4YPA A;  5EX3 A;  5KJN A;  5F6L A;  4J7I A;  3RU0 A;  3OXG A;  4MI5 A;  3PDN A;  4AU7 A;  5KJK A;  5JIY A;  3RQ4 A;  3QWV A;  2RFI A;  2QPW A;  3MEK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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