2O8JA

Human euchromatic histone methyltransferase 2
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
262
structure length
254
Chain Sequence
KIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDYFTCQCGSEKCKHSAEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Histone-lysine N-methyltransferase, H3 lysine-9 specific 3
publication title Structural biology of human H3K9 methyltransferases
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 59
structure length 254
sequence length 262
chains with identical sequence B, C, D
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2006-12-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 2o8jA00
3F9ZA 3M55A 4O6FA 3M5AA 4J83A 3M53A 3M56A 3BO5A 4E47A 3OPEA 5ARGA 5T0MA 3PDNA 3S7BA 3DALA 1PEGA 3IHXA 3OS5A 1MVHA 1N6CA 4Z4PA 5HI7A 4MI5A 3HNAA 4C1QA 5CCLA 1XQHA 2IGQA 4QEPA 3RAYA 2G46A 3FPDA 5T0KA 2JV0A 3N71A 5F59A 5ARFA 3RQ4A 4QEOA 3KMTA 3QWVA 2BQZA 3S8PA 1ZKKA 5LSXA 1ML9A 2RFIA 5JINA 3S7DA 4QENA 3OXFA 5CPRB 3QWWA 2F69A 5KJMA 3DB5A 3SWCA 3VV0A 2W5ZA 4BUPA 5JHNA 1O9SA 4MI0A 4IJ8A 2W5YA 3M54A 3OXGA 4JLGA 5JJ0A 3F9YA 4LDGA 5CCMA 3OOIA 4I51A 1MT6A 3S7JA 4J7FA 4J7IA 3F9WA 3MO5A 3RIBA 3VUZA 4FMUA 3S7FA 3M59A 5EX3A 4YPAA 2QPWA 4IJDA 5LSZA 3EP0A 3TG4A 3MEKA 3M57A 3KMJA 3OXLA 5F5EA 4YPUA 5KJKA 5EX0A 1N3JA 4NJ5A 4YNPA 5F6KC 1H3IA 5JIYA 3QWPA 5TEGA 3TG5A 3F9XA 1N6AA 5T5GA 4YPEA 2O8JA 4RZ0A 4NVQA 4J8OA 1MVXA 5HQ8A 5TTFA 3MO2A 3SW9A 5KJLA 4JDSA 3CBOA 4WUYA 3RU0A 4YNDA 5EG2A 4AU7A 3MO0A 3K5KA 5AYFA 5TH7A 5F6LA 3M58A 1MUFA 2R3AA 4O30A 4H12A 3KMAA 3CBMA 4YNMA 5KJNA 3RJWA 3CBPA
chains in the Genus database with same CATH superfamily
3F9ZA 3M55A 4O6FA 3M5AA 4J83A 3M53A 3M56A 3BO5A 4E47A 3OPEA 5ARGA 5T0MA 3PDNA 3S7BA 3DALA 1PEGA 3IHXA 3OS5A 1MVHA 1N6CA 4Z4PA 5HI7A 4MI5A 3HNAA 4C1QA 5CCLA 1XQHA 2IGQA 4QEPA 3RAYA 2G46A 3FPDA 5T0KA 2JV0A 3N71A 5F59A 5ARFA 3RQ4A 4QEOA 3KMTA 3QWVA 2BQZA 3S8PA 1ZKKA 5LSXA 1ML9A 2RFIA 5JINA 3S7DA 4QENA 3OXFA 5CPRB 3QWWA 2F69A 5KJMA 3DB5A 3SWCA 3VV0A 2W5ZA 4BUPA 5JHNA 1O9SA 4MI0A 4IJ8A 2W5YA 3M54A 3OXGA 4JLGA 5JJ0A 3F9YA 4LDGA 5CCMA 3OOIA 4I51A 1MT6A 3S7JA 4J7FA 4J7IA 3F9WA 3MO5A 3RIBA 3VUZA 4FMUA 3S7FA 3M59A 5EX3A 4YPAA 2QPWA 4IJDA 5LSZA 3EP0A 3TG4A 3MEKA 3M57A 3KMJA 3OXLA 5F5EA 4YPUA 5KJKA 5EX0A 1N3JA 4NJ5A 4YNPA 5F6KC 1H3IA 5JIYA 3QWPA 5TEGA 3TG5A 3F9XA 1N6AA 5T5GA 4YPEA 2O8JA 4RZ0A 4NVQA 4J8OA 1MVXA 5HQ8A 5TTFA 3MO2A 3SW9A 5KJLA 4JDSA 3CBOA 4WUYA 3RU0A 4YNDA 5EG2A 4AU7A 3MO0A 3K5KA 5AYFA 5TH7A 5F6LA 3M58A 1MUFA 2R3AA 4O30A 4H12A 3KMAA 3CBMA 4YNMA 5KJNA 3RJWA 3CBPA
chains in the Genus database with same CATH topology
3F9ZA 3M55A 4O6FA 3M5AA 4J83A 3M53A 3M56A 3BO5A 4E47A 3OPEA 5ARGA 5T0MA 3PDNA 3S7BA 3DALA 1PEGA 3IHXA 3OS5A 1MVHA 1N6CA 4Z4PA 5HI7A 4MI5A 3HNAA 4C1QA 5CCLA 1XQHA 2IGQA 4QEPA 3RAYA 2G46A 3FPDA 5T0KA 2JV0A 3N71A 5F59A 5ARFA 3RQ4A 4QEOA 3KMTA 3QWVA 2BQZA 3S8PA 1ZKKA 5LSXA 1ML9A 2RFIA 5JINA 3S7DA 4QENA 3OXFA 5CPRB 3QWWA 2F69A 5KJMA 3DB5A 3SWCA 3VV0A 2W5ZA 4BUPA 5JHNA 1O9SA 4MI0A 4IJ8A 2W5YA 3M54A 3OXGA 4JLGA 5JJ0A 3F9YA 4LDGA 5CCMA 3OOIA 4I51A 1MT6A 3S7JA 4J7FA 4J7IA 3F9WA 3MO5A 3RIBA 3VUZA 4FMUA 3S7FA 3M59A 5EX3A 4YPAA 2QPWA 4IJDA 5LSZA 3EP0A 3TG4A 3MEKA 3M57A 3KMJA 3OXLA 5F5EA 4YPUA 5KJKA 5EX0A 1N3JA 4NJ5A 4YNPA 5F6KC 1H3IA 5JIYA 3QWPA 5TEGA 3TG5A 3F9XA 1N6AA 5T5GA 4YPEA 2O8JA 4RZ0A 4NVQA 4J8OA 1MVXA 5HQ8A 5TTFA 3MO2A 3SW9A 5KJLA 4JDSA 3CBOA 4WUYA 3RU0A 4YNDA 5EG2A 4AU7A 3MO0A 3K5KA 5AYFA 5TH7A 5F6LA 3M58A 1MUFA 2R3AA 4O30A 4H12A 3KMAA 3CBMA 4YNMA 5KJNA 3RJWA 3CBPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F9Z A;  3M55 A;  4O6F A;  3M5A A;  4J83 A;  3M53 A;  3M56 A;  3BO5 A;  4E47 A;  3OPE A;  5ARG A;  5T0M A;  3PDN A;  3S7B A;  3DAL A;  1PEG A;  3IHX A;  3OS5 A;  1MVH A;  1N6C A;  4Z4P A;  5HI7 A;  4MI5 A;  3HNA A;  4C1Q A;  5CCL A;  1XQH A;  2IGQ A;  4QEP A;  3RAY A;  2G46 A;  3FPD A;  5T0K A;  2JV0 A;  3N71 A;  5F59 A;  5ARF A;  3RQ4 A;  4QEO A;  3KMT A;  3QWV A;  2BQZ A;  3S8P A;  1ZKK A;  5LSX A;  1ML9 A;  2RFI A;  5JIN A;  3S7D A;  4QEN A;  3OXF A;  5CPR B;  3QWW A;  2F69 A;  5KJM A;  3DB5 A;  3SWC A;  3VV0 A;  2W5Z A;  4BUP A;  5JHN A;  1O9S A;  4MI0 A;  4IJ8 A;  2W5Y A;  3M54 A;  3OXG A;  4JLG A;  5JJ0 A;  3F9Y A;  4LDG A;  5CCM A;  3OOI A;  4I51 A;  1MT6 A;  3S7J A;  4J7F A;  4J7I A;  3F9W A;  3MO5 A;  3RIB A;  3VUZ A;  4FMU A;  3S7F A;  3M59 A;  5EX3 A;  4YPA A;  2QPW A;  4IJD A;  5LSZ A;  3EP0 A;  3TG4 A;  3MEK A;  3M57 A;  3KMJ A;  3OXL A;  5F5E A;  4YPU A;  5KJK A;  5EX0 A;  1N3J A;  4NJ5 A;  4YNP A;  5F6K C;  1H3I A;  5JIY A;  3QWP A;  5TEG A;  3TG5 A;  3F9X A;  1N6A A;  5T5G A;  4YPE A;  2O8J A;  4RZ0 A;  4NVQ A;  4J8O A;  1MVX A;  5HQ8 A;  5TTF A;  3MO2 A;  3SW9 A;  5KJL A;  4JDS A;  3CBO A;  4WUY A;  3RU0 A;  4YND A;  5EG2 A;  4AU7 A;  3MO0 A;  3K5K A;  5AYF A;  5TH7 A;  5F6L A;  3M58 A;  1MUF A;  2R3A A;  4O30 A;  4H12 A;  3KMA A;  3CBM A;  4YNM A;  5KJN A;  3RJW A;  3CBP A; 
#chains in the Genus database with same CATH topology
 3F9Z A;  3M55 A;  4O6F A;  3M5A A;  4J83 A;  3M53 A;  3M56 A;  3BO5 A;  4E47 A;  3OPE A;  5ARG A;  5T0M A;  3PDN A;  3S7B A;  3DAL A;  1PEG A;  3IHX A;  3OS5 A;  1MVH A;  1N6C A;  4Z4P A;  5HI7 A;  4MI5 A;  3HNA A;  4C1Q A;  5CCL A;  1XQH A;  2IGQ A;  4QEP A;  3RAY A;  2G46 A;  3FPD A;  5T0K A;  2JV0 A;  3N71 A;  5F59 A;  5ARF A;  3RQ4 A;  4QEO A;  3KMT A;  3QWV A;  2BQZ A;  3S8P A;  1ZKK A;  5LSX A;  1ML9 A;  2RFI A;  5JIN A;  3S7D A;  4QEN A;  3OXF A;  5CPR B;  3QWW A;  2F69 A;  5KJM A;  3DB5 A;  3SWC A;  3VV0 A;  2W5Z A;  4BUP A;  5JHN A;  1O9S A;  4MI0 A;  4IJ8 A;  2W5Y A;  3M54 A;  3OXG A;  4JLG A;  5JJ0 A;  3F9Y A;  4LDG A;  5CCM A;  3OOI A;  4I51 A;  1MT6 A;  3S7J A;  4J7F A;  4J7I A;  3F9W A;  3MO5 A;  3RIB A;  3VUZ A;  4FMU A;  3S7F A;  3M59 A;  5EX3 A;  4YPA A;  2QPW A;  4IJD A;  5LSZ A;  3EP0 A;  3TG4 A;  3MEK A;  3M57 A;  3KMJ A;  3OXL A;  5F5E A;  4YPU A;  5KJK A;  5EX0 A;  1N3J A;  4NJ5 A;  4YNP A;  5F6K C;  1H3I A;  5JIY A;  3QWP A;  5TEG A;  3TG5 A;  3F9X A;  1N6A A;  5T5G A;  4YPE A;  2O8J A;  4RZ0 A;  4NVQ A;  4J8O A;  1MVX A;  5HQ8 A;  5TTF A;  3MO2 A;  3SW9 A;  5KJL A;  4JDS A;  3CBO A;  4WUY A;  3RU0 A;  4YND A;  5EG2 A;  4AU7 A;  3MO0 A;  3K5K A;  5AYF A;  5TH7 A;  5F6L A;  3M58 A;  1MUF A;  2R3A A;  4O30 A;  4H12 A;  3KMA A;  3CBM A;  4YNM A;  5KJN A;  3RJW A;  3CBP A; 
#chains in the Genus database with same CATH homology
 3F9Z A;  3M55 A;  4O6F A;  3M5A A;  4J83 A;  3M53 A;  3M56 A;  3BO5 A;  4E47 A;  3OPE A;  5ARG A;  5T0M A;  3PDN A;  3S7B A;  3DAL A;  1PEG A;  3IHX A;  3OS5 A;  1MVH A;  1N6C A;  4Z4P A;  5HI7 A;  4MI5 A;  3HNA A;  4C1Q A;  5CCL A;  1XQH A;  2IGQ A;  4QEP A;  3RAY A;  2G46 A;  3FPD A;  5T0K A;  2JV0 A;  3N71 A;  5F59 A;  5ARF A;  3RQ4 A;  4QEO A;  3KMT A;  3QWV A;  2BQZ A;  3S8P A;  1ZKK A;  5LSX A;  1ML9 A;  2RFI A;  5JIN A;  3S7D A;  4QEN A;  3OXF A;  5CPR B;  3QWW A;  2F69 A;  5KJM A;  3DB5 A;  3SWC A;  3VV0 A;  2W5Z A;  4BUP A;  5JHN A;  1O9S A;  4MI0 A;  4IJ8 A;  2W5Y A;  3M54 A;  3OXG A;  4JLG A;  5JJ0 A;  3F9Y A;  4LDG A;  5CCM A;  3OOI A;  4I51 A;  1MT6 A;  3S7J A;  4J7F A;  4J7I A;  3F9W A;  3MO5 A;  3RIB A;  3VUZ A;  4FMU A;  3S7F A;  3M59 A;  5EX3 A;  4YPA A;  2QPW A;  4IJD A;  5LSZ A;  3EP0 A;  3TG4 A;  3MEK A;  3M57 A;  3KMJ A;  3OXL A;  5F5E A;  4YPU A;  5KJK A;  5EX0 A;  1N3J A;  4NJ5 A;  4YNP A;  5F6K C;  1H3I A;  5JIY A;  3QWP A;  5TEG A;  3TG5 A;  3F9X A;  1N6A A;  5T5G A;  4YPE A;  2O8J A;  4RZ0 A;  4NVQ A;  4J8O A;  1MVX A;  5HQ8 A;  5TTF A;  3MO2 A;  3SW9 A;  5KJL A;  4JDS A;  3CBO A;  4WUY A;  3RU0 A;  4YND A;  5EG2 A;  4AU7 A;  3MO0 A;  3K5K A;  5AYF A;  5TH7 A;  5F6L A;  3M58 A;  1MUF A;  2R3A A;  4O30 A;  4H12 A;  3KMA A;  3CBM A;  4YNM A;  5KJN A;  3RJW A;  3CBP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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