2O8JA

Human euchromatic histone methyltransferase 2
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
262
structure length
254
Chain Sequence
KIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDYFTCQCGSEKCKHSAEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural biology of human H3K9 methyltransferases
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
molecule keywords Histone-lysine N-methyltransferase, H3 lysine-9 specific 3
total genus 59
structure length 254
sequence length 262
chains with identical sequence B, C, D
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2006-12-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 2o8jA00
5JHNA 3CBPA 3CBOA 4E47A 3DALA 1O9SA 5AYFA 3VV0A 5CCMA 4JLGA 4LDGA 1ZKKA 3CBMA 5ARGA 3S7JA 3MO0A 5LSZA 5TH7A 5JIYA 3N71A 5LSXA 4Z4PA 4YNDA 1ML9A 4I51A 3FPDA 3M59A 3MEKA 3TG5A 3SWCA 3TG4A 3M53A 3OXGA 4J7FA 4QEOA 5EG2A 3S7DA 3S7FA 4AU7A 5F6LA 3OXLA 3M56A 3QWPA 5EX0A 3OXFA 3HNAA 1H3IA 3RQ4A 4FMUA 4IJDA 2W5YA 4O30A 3MO5A 5T0KA 5KJMA 2QPWA 5T5GA 4J83A 4MI5A 5JJ0A 2R3AA 5KJKA 5F5EA 1N6CA 3RAYA 3OOIA 3OPEA 3F9XA 1MVXA 4NVQA 2JV0A 4QENA 1XQHA 4YNPA 4MI0A 4H12A 3M54A 4QEPA 4NJ5A 1MT6A 5JINA 3BO5A 3RJWA 3EP0A 5F6KC 5KJLA 5CCLA 5HQ8A 5KJNA 4YPAA 5F59A 3MO2A 3KMJA 2BQZA 3QWVA 3S7BA 4YPEA 5CPRB 5EX3A 2W5ZA 3F9WA 4J7IA 5HI7A 3RIBA 4BUPA 2RFIA 3DB5A 2F69A 4YPUA 4JDSA 3S8PA 1PEGA 3OS5A 1MVHA 4J8OA 3PDNA 2O8JA 2IGQA 3QWWA 3M58A 3IHXA 2G46A 3KMAA 3SW9A 3F9ZA 3K5KA 1MUFA 1N3JA 3RU0A 4RZ0A 4IJ8A 4WUYA 5ARFA 3F9YA 3M55A 5TTFA 4O6FA 1N6AA 5T0MA 3KMTA 4C1QA 3VUZA 4YNMA 3M5AA 5TEGA 3M57A
chains in the Genus database with same CATH superfamily
5JHNA 3CBPA 3CBOA 4E47A 3DALA 1O9SA 5AYFA 3VV0A 5CCMA 4JLGA 4LDGA 1ZKKA 3CBMA 5ARGA 3S7JA 3MO0A 5LSZA 5TH7A 5JIYA 3N71A 5LSXA 4Z4PA 4YNDA 1ML9A 4I51A 3FPDA 3M59A 3MEKA 3TG5A 3SWCA 3TG4A 3M53A 3OXGA 4J7FA 4QEOA 5EG2A 3S7DA 3S7FA 4AU7A 5F6LA 3OXLA 3M56A 3QWPA 5EX0A 3OXFA 3HNAA 1H3IA 3RQ4A 4FMUA 4IJDA 2W5YA 4O30A 3MO5A 5T0KA 5KJMA 2QPWA 5T5GA 4J83A 4MI5A 5JJ0A 2R3AA 5KJKA 5F5EA 1N6CA 3RAYA 3OOIA 3OPEA 3F9XA 1MVXA 4NVQA 2JV0A 4QENA 1XQHA 4YNPA 4MI0A 4H12A 3M54A 4QEPA 4NJ5A 1MT6A 5JINA 3BO5A 3RJWA 3EP0A 5F6KC 5KJLA 5CCLA 5HQ8A 5KJNA 4YPAA 5F59A 3MO2A 3KMJA 2BQZA 3QWVA 3S7BA 4YPEA 5CPRB 5EX3A 2W5ZA 3F9WA 4J7IA 5HI7A 3RIBA 4BUPA 2RFIA 3DB5A 2F69A 4YPUA 4JDSA 3S8PA 1PEGA 3OS5A 1MVHA 4J8OA 3PDNA 2O8JA 2IGQA 3QWWA 3M58A 3IHXA 2G46A 3KMAA 3SW9A 3F9ZA 3K5KA 1MUFA 1N3JA 3RU0A 4RZ0A 4IJ8A 4WUYA 5ARFA 3F9YA 3M55A 5TTFA 4O6FA 1N6AA 5T0MA 3KMTA 4C1QA 3VUZA 4YNMA 3M5AA 5TEGA 3M57A
chains in the Genus database with same CATH topology
5JHNA 3CBPA 3CBOA 4E47A 3DALA 1O9SA 5AYFA 3VV0A 5CCMA 4JLGA 4LDGA 1ZKKA 3CBMA 5ARGA 3S7JA 3MO0A 5LSZA 5TH7A 5JIYA 3N71A 5LSXA 4Z4PA 4YNDA 1ML9A 4I51A 3FPDA 3M59A 3MEKA 3TG5A 3SWCA 3TG4A 3M53A 3OXGA 4J7FA 4QEOA 5EG2A 3S7DA 3S7FA 4AU7A 5F6LA 3OXLA 3M56A 3QWPA 5EX0A 3OXFA 3HNAA 1H3IA 3RQ4A 4FMUA 4IJDA 2W5YA 4O30A 3MO5A 5T0KA 5KJMA 2QPWA 5T5GA 4J83A 4MI5A 5JJ0A 2R3AA 5KJKA 5F5EA 1N6CA 3RAYA 3OOIA 3OPEA 3F9XA 1MVXA 4NVQA 2JV0A 4QENA 1XQHA 4YNPA 4MI0A 4H12A 3M54A 4QEPA 4NJ5A 1MT6A 5JINA 3BO5A 3RJWA 3EP0A 5F6KC 5KJLA 5CCLA 5HQ8A 5KJNA 4YPAA 5F59A 3MO2A 3KMJA 2BQZA 3QWVA 3S7BA 4YPEA 5CPRB 5EX3A 2W5ZA 3F9WA 4J7IA 5HI7A 3RIBA 4BUPA 2RFIA 3DB5A 2F69A 4YPUA 4JDSA 3S8PA 1PEGA 3OS5A 1MVHA 4J8OA 3PDNA 2O8JA 2IGQA 3QWWA 3M58A 3IHXA 2G46A 3KMAA 3SW9A 3F9ZA 3K5KA 1MUFA 1N3JA 3RU0A 4RZ0A 4IJ8A 4WUYA 5ARFA 3F9YA 3M55A 5TTFA 4O6FA 1N6AA 5T0MA 3KMTA 4C1QA 3VUZA 4YNMA 3M5AA 5TEGA 3M57A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JHN A;  3CBP A;  3CBO A;  4E47 A;  3DAL A;  1O9S A;  5AYF A;  3VV0 A;  5CCM A;  4JLG A;  4LDG A;  1ZKK A;  3CBM A;  5ARG A;  3S7J A;  3MO0 A;  5LSZ A;  5TH7 A;  5JIY A;  3N71 A;  5LSX A;  4Z4P A;  4YND A;  1ML9 A;  4I51 A;  3FPD A;  3M59 A;  3MEK A;  3TG5 A;  3SWC A;  3TG4 A;  3M53 A;  3OXG A;  4J7F A;  4QEO A;  5EG2 A;  3S7D A;  3S7F A;  4AU7 A;  5F6L A;  3OXL A;  3M56 A;  3QWP A;  5EX0 A;  3OXF A;  3HNA A;  1H3I A;  3RQ4 A;  4FMU A;  4IJD A;  2W5Y A;  4O30 A;  3MO5 A;  5T0K A;  5KJM A;  2QPW A;  5T5G A;  4J83 A;  4MI5 A;  5JJ0 A;  2R3A A;  5KJK A;  5F5E A;  1N6C A;  3RAY A;  3OOI A;  3OPE A;  3F9X A;  1MVX A;  4NVQ A;  2JV0 A;  4QEN A;  1XQH A;  4YNP A;  4MI0 A;  4H12 A;  3M54 A;  4QEP A;  4NJ5 A;  1MT6 A;  5JIN A;  3BO5 A;  3RJW A;  3EP0 A;  5F6K C;  5KJL A;  5CCL A;  5HQ8 A;  5KJN A;  4YPA A;  5F59 A;  3MO2 A;  3KMJ A;  2BQZ A;  3QWV A;  3S7B A;  4YPE A;  5CPR B;  5EX3 A;  2W5Z A;  3F9W A;  4J7I A;  5HI7 A;  3RIB A;  4BUP A;  2RFI A;  3DB5 A;  2F69 A;  4YPU A;  4JDS A;  3S8P A;  1PEG A;  3OS5 A;  1MVH A;  4J8O A;  3PDN A;  2O8J A;  2IGQ A;  3QWW A;  3M58 A;  3IHX A;  2G46 A;  3KMA A;  3SW9 A;  3F9Z A;  3K5K A;  1MUF A;  1N3J A;  3RU0 A;  4RZ0 A;  4IJ8 A;  4WUY A;  5ARF A;  3F9Y A;  3M55 A;  5TTF A;  4O6F A;  1N6A A;  5T0M A;  3KMT A;  4C1Q A;  3VUZ A;  4YNM A;  3M5A A;  5TEG A;  3M57 A; 
#chains in the Genus database with same CATH topology
 5JHN A;  3CBP A;  3CBO A;  4E47 A;  3DAL A;  1O9S A;  5AYF A;  3VV0 A;  5CCM A;  4JLG A;  4LDG A;  1ZKK A;  3CBM A;  5ARG A;  3S7J A;  3MO0 A;  5LSZ A;  5TH7 A;  5JIY A;  3N71 A;  5LSX A;  4Z4P A;  4YND A;  1ML9 A;  4I51 A;  3FPD A;  3M59 A;  3MEK A;  3TG5 A;  3SWC A;  3TG4 A;  3M53 A;  3OXG A;  4J7F A;  4QEO A;  5EG2 A;  3S7D A;  3S7F A;  4AU7 A;  5F6L A;  3OXL A;  3M56 A;  3QWP A;  5EX0 A;  3OXF A;  3HNA A;  1H3I A;  3RQ4 A;  4FMU A;  4IJD A;  2W5Y A;  4O30 A;  3MO5 A;  5T0K A;  5KJM A;  2QPW A;  5T5G A;  4J83 A;  4MI5 A;  5JJ0 A;  2R3A A;  5KJK A;  5F5E A;  1N6C A;  3RAY A;  3OOI A;  3OPE A;  3F9X A;  1MVX A;  4NVQ A;  2JV0 A;  4QEN A;  1XQH A;  4YNP A;  4MI0 A;  4H12 A;  3M54 A;  4QEP A;  4NJ5 A;  1MT6 A;  5JIN A;  3BO5 A;  3RJW A;  3EP0 A;  5F6K C;  5KJL A;  5CCL A;  5HQ8 A;  5KJN A;  4YPA A;  5F59 A;  3MO2 A;  3KMJ A;  2BQZ A;  3QWV A;  3S7B A;  4YPE A;  5CPR B;  5EX3 A;  2W5Z A;  3F9W A;  4J7I A;  5HI7 A;  3RIB A;  4BUP A;  2RFI A;  3DB5 A;  2F69 A;  4YPU A;  4JDS A;  3S8P A;  1PEG A;  3OS5 A;  1MVH A;  4J8O A;  3PDN A;  2O8J A;  2IGQ A;  3QWW A;  3M58 A;  3IHX A;  2G46 A;  3KMA A;  3SW9 A;  3F9Z A;  3K5K A;  1MUF A;  1N3J A;  3RU0 A;  4RZ0 A;  4IJ8 A;  4WUY A;  5ARF A;  3F9Y A;  3M55 A;  5TTF A;  4O6F A;  1N6A A;  5T0M A;  3KMT A;  4C1Q A;  3VUZ A;  4YNM A;  3M5A A;  5TEG A;  3M57 A; 
#chains in the Genus database with same CATH homology
 5JHN A;  3CBP A;  3CBO A;  4E47 A;  3DAL A;  1O9S A;  5AYF A;  3VV0 A;  5CCM A;  4JLG A;  4LDG A;  1ZKK A;  3CBM A;  5ARG A;  3S7J A;  3MO0 A;  5LSZ A;  5TH7 A;  5JIY A;  3N71 A;  5LSX A;  4Z4P A;  4YND A;  1ML9 A;  4I51 A;  3FPD A;  3M59 A;  3MEK A;  3TG5 A;  3SWC A;  3TG4 A;  3M53 A;  3OXG A;  4J7F A;  4QEO A;  5EG2 A;  3S7D A;  3S7F A;  4AU7 A;  5F6L A;  3OXL A;  3M56 A;  3QWP A;  5EX0 A;  3OXF A;  3HNA A;  1H3I A;  3RQ4 A;  4FMU A;  4IJD A;  2W5Y A;  4O30 A;  3MO5 A;  5T0K A;  5KJM A;  2QPW A;  5T5G A;  4J83 A;  4MI5 A;  5JJ0 A;  2R3A A;  5KJK A;  5F5E A;  1N6C A;  3RAY A;  3OOI A;  3OPE A;  3F9X A;  1MVX A;  4NVQ A;  2JV0 A;  4QEN A;  1XQH A;  4YNP A;  4MI0 A;  4H12 A;  3M54 A;  4QEP A;  4NJ5 A;  1MT6 A;  5JIN A;  3BO5 A;  3RJW A;  3EP0 A;  5F6K C;  5KJL A;  5CCL A;  5HQ8 A;  5KJN A;  4YPA A;  5F59 A;  3MO2 A;  3KMJ A;  2BQZ A;  3QWV A;  3S7B A;  4YPE A;  5CPR B;  5EX3 A;  2W5Z A;  3F9W A;  4J7I A;  5HI7 A;  3RIB A;  4BUP A;  2RFI A;  3DB5 A;  2F69 A;  4YPU A;  4JDS A;  3S8P A;  1PEG A;  3OS5 A;  1MVH A;  4J8O A;  3PDN A;  2O8J A;  2IGQ A;  3QWW A;  3M58 A;  3IHX A;  2G46 A;  3KMA A;  3SW9 A;  3F9Z A;  3K5K A;  1MUF A;  1N3J A;  3RU0 A;  4RZ0 A;  4IJ8 A;  4WUY A;  5ARF A;  3F9Y A;  3M55 A;  5TTF A;  4O6F A;  1N6A A;  5T0M A;  3KMT A;  4C1Q A;  3VUZ A;  4YNM A;  3M5A A;  5TEG A;  3M57 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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