5JJ0A

Structure of g9a set-domain with histone h3k9m peptide and excess sah
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
273
structure length
273
Chain Sequence
b'IRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQSR'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Histone-lysine N-methyltransferase EHMT2
publication title S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 76
structure length 273
sequence length 273
chains with identical sequence B
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2016-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 5jj0A00
3MO5A 4LDGA 2RFIA 3QWVA 1MT6A 3KMTA 5F59A 5TH7A 3OS5A 2W5YA 4YNMA 5ARGA 3MO2A 5HQ8A 5T0KA 3S7BA 3TG4A 4J7FA 3F9XA 3CBMA 2BQZA 3BO5A 4RZ0A 2W5ZA 5KJLA 4IJDA 1ML9A 5F6KC 3DB5A 3CBOA 3DALA 4I51A 3M57A 1MVHA 2O8JA 5LSXA 1N6CA 3F9YA 4YPEA 4WUYA 3IHXA 3HNAA 4MI5A 2QPWA 3PDNA 5LSZA 4QEOA 4QENA 3CBPA 5EX3A 3MO0A 1ZKKA 4J8OA 5CCMA 1MVXA 4C1QA 4YNDA 1N3JA 2R3AA 5TTFA 3M53A 3M54A 2IGQA 5ARFA 4JLGA 4YPUA 3TG5A 3KMJA 4O30A 4FMUA 3OXGA 2F69A 3OXLA 5EG2A 4Z4PA 3QWWA 1H3IA 5EX0A 3N71A 5AYFA 3KMAA 4JDSA 2G46A 3QWPA 1MUFA 3S8PA 5JIYA 5KJKA 3RJWA 3RIBA 5JJ0A 3RAYA 4QEPA 3S7DA 3S7JA 3M59A 5KJNA 4NVQA 3MEKA 3VV0A 5F5EA 5T5GA 5T0MA 4YPAA 3K5KA 4H12A 3F9ZA 3OPEA 4J83A 3M5AA 4MI0A 4NJ5A 3M56A 5CPRB 3M58A 5CCLA 3OOIA 3RQ4A 5JINA 3OXFA 3F9WA 4BUPA 5KJMA 4J7IA 5TEGA 3M55A 3FPDA 4IJ8A 3S7FA 4O6FA 1O9SA 3SW9A 1PEGA 3VUZA 3RU0A 4AU7A 5HI7A 1N6AA 4YNPA 5F6LA 3SWCA 2JV0A 4E47A 3EP0A 5JHNA 1XQHA
chains in the Genus database with same CATH superfamily
3MO5A 4LDGA 2RFIA 3QWVA 1MT6A 3KMTA 5F59A 5TH7A 3OS5A 2W5YA 4YNMA 5ARGA 3MO2A 5HQ8A 5T0KA 3S7BA 3TG4A 4J7FA 3F9XA 3CBMA 2BQZA 3BO5A 4RZ0A 2W5ZA 5KJLA 4IJDA 1ML9A 5F6KC 3DB5A 3CBOA 3DALA 4I51A 3M57A 1MVHA 2O8JA 5LSXA 1N6CA 3F9YA 4YPEA 4WUYA 3IHXA 3HNAA 4MI5A 2QPWA 3PDNA 5LSZA 4QEOA 4QENA 3CBPA 5EX3A 3MO0A 1ZKKA 4J8OA 5CCMA 1MVXA 4C1QA 4YNDA 1N3JA 2R3AA 5TTFA 3M53A 3M54A 2IGQA 5ARFA 4JLGA 4YPUA 3TG5A 3KMJA 4O30A 4FMUA 3OXGA 2F69A 3OXLA 5EG2A 4Z4PA 3QWWA 1H3IA 5EX0A 3N71A 5AYFA 3KMAA 4JDSA 2G46A 3QWPA 1MUFA 3S8PA 5JIYA 5KJKA 3RJWA 3RIBA 5JJ0A 3RAYA 4QEPA 3S7DA 3S7JA 3M59A 5KJNA 4NVQA 3MEKA 3VV0A 5F5EA 5T5GA 5T0MA 4YPAA 3K5KA 4H12A 3F9ZA 3OPEA 4J83A 3M5AA 4MI0A 4NJ5A 3M56A 5CPRB 3M58A 5CCLA 3OOIA 3RQ4A 5JINA 3OXFA 3F9WA 4BUPA 5KJMA 4J7IA 5TEGA 3M55A 3FPDA 4IJ8A 3S7FA 4O6FA 1O9SA 3SW9A 1PEGA 3VUZA 3RU0A 4AU7A 5HI7A 1N6AA 4YNPA 5F6LA 3SWCA 2JV0A 4E47A 3EP0A 5JHNA 1XQHA
chains in the Genus database with same CATH topology
3MO5A 4LDGA 2RFIA 3QWVA 1MT6A 3KMTA 5F59A 5TH7A 3OS5A 2W5YA 4YNMA 5ARGA 3MO2A 5HQ8A 5T0KA 3S7BA 3TG4A 4J7FA 3F9XA 3CBMA 2BQZA 3BO5A 4RZ0A 2W5ZA 5KJLA 4IJDA 1ML9A 5F6KC 3DB5A 3CBOA 3DALA 4I51A 3M57A 1MVHA 2O8JA 5LSXA 1N6CA 3F9YA 4YPEA 4WUYA 3IHXA 3HNAA 4MI5A 2QPWA 3PDNA 5LSZA 4QEOA 4QENA 3CBPA 5EX3A 3MO0A 1ZKKA 4J8OA 5CCMA 1MVXA 4C1QA 4YNDA 1N3JA 2R3AA 5TTFA 3M53A 3M54A 2IGQA 5ARFA 4JLGA 4YPUA 3TG5A 3KMJA 4O30A 4FMUA 3OXGA 2F69A 3OXLA 5EG2A 4Z4PA 3QWWA 1H3IA 5EX0A 3N71A 5AYFA 3KMAA 4JDSA 2G46A 3QWPA 1MUFA 3S8PA 5JIYA 5KJKA 3RJWA 3RIBA 5JJ0A 3RAYA 4QEPA 3S7DA 3S7JA 3M59A 5KJNA 4NVQA 3MEKA 3VV0A 5F5EA 5T5GA 5T0MA 4YPAA 3K5KA 4H12A 3F9ZA 3OPEA 4J83A 3M5AA 4MI0A 4NJ5A 3M56A 5CPRB 3M58A 5CCLA 3OOIA 3RQ4A 5JINA 3OXFA 3F9WA 4BUPA 5KJMA 4J7IA 5TEGA 3M55A 3FPDA 4IJ8A 3S7FA 4O6FA 1O9SA 3SW9A 1PEGA 3VUZA 3RU0A 4AU7A 5HI7A 1N6AA 4YNPA 5F6LA 3SWCA 2JV0A 4E47A 3EP0A 5JHNA 1XQHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MO5 A;  4LDG A;  2RFI A;  3QWV A;  1MT6 A;  3KMT A;  5F59 A;  5TH7 A;  3OS5 A;  2W5Y A;  4YNM A;  5ARG A;  3MO2 A;  5HQ8 A;  5T0K A;  3S7B A;  3TG4 A;  4J7F A;  3F9X A;  3CBM A;  2BQZ A;  3BO5 A;  4RZ0 A;  2W5Z A;  5KJL A;  4IJD A;  1ML9 A;  5F6K C;  3DB5 A;  3CBO A;  3DAL A;  4I51 A;  3M57 A;  1MVH A;  2O8J A;  5LSX A;  1N6C A;  3F9Y A;  4YPE A;  4WUY A;  3IHX A;  3HNA A;  4MI5 A;  2QPW A;  3PDN A;  5LSZ A;  4QEO A;  4QEN A;  3CBP A;  5EX3 A;  3MO0 A;  1ZKK A;  4J8O A;  5CCM A;  1MVX A;  4C1Q A;  4YND A;  1N3J A;  2R3A A;  5TTF A;  3M53 A;  3M54 A;  2IGQ A;  5ARF A;  4JLG A;  4YPU A;  3TG5 A;  3KMJ A;  4O30 A;  4FMU A;  3OXG A;  2F69 A;  3OXL A;  5EG2 A;  4Z4P A;  3QWW A;  1H3I A;  5EX0 A;  3N71 A;  5AYF A;  3KMA A;  4JDS A;  2G46 A;  3QWP A;  1MUF A;  3S8P A;  5JIY A;  5KJK A;  3RJW A;  3RIB A;  5JJ0 A;  3RAY A;  4QEP A;  3S7D A;  3S7J A;  3M59 A;  5KJN A;  4NVQ A;  3MEK A;  3VV0 A;  5F5E A;  5T5G A;  5T0M A;  4YPA A;  3K5K A;  4H12 A;  3F9Z A;  3OPE A;  4J83 A;  3M5A A;  4MI0 A;  4NJ5 A;  3M56 A;  5CPR B;  3M58 A;  5CCL A;  3OOI A;  3RQ4 A;  5JIN A;  3OXF A;  3F9W A;  4BUP A;  5KJM A;  4J7I A;  5TEG A;  3M55 A;  3FPD A;  4IJ8 A;  3S7F A;  4O6F A;  1O9S A;  3SW9 A;  1PEG A;  3VUZ A;  3RU0 A;  4AU7 A;  5HI7 A;  1N6A A;  4YNP A;  5F6L A;  3SWC A;  2JV0 A;  4E47 A;  3EP0 A;  5JHN A;  1XQH A; 
#chains in the Genus database with same CATH topology
 3MO5 A;  4LDG A;  2RFI A;  3QWV A;  1MT6 A;  3KMT A;  5F59 A;  5TH7 A;  3OS5 A;  2W5Y A;  4YNM A;  5ARG A;  3MO2 A;  5HQ8 A;  5T0K A;  3S7B A;  3TG4 A;  4J7F A;  3F9X A;  3CBM A;  2BQZ A;  3BO5 A;  4RZ0 A;  2W5Z A;  5KJL A;  4IJD A;  1ML9 A;  5F6K C;  3DB5 A;  3CBO A;  3DAL A;  4I51 A;  3M57 A;  1MVH A;  2O8J A;  5LSX A;  1N6C A;  3F9Y A;  4YPE A;  4WUY A;  3IHX A;  3HNA A;  4MI5 A;  2QPW A;  3PDN A;  5LSZ A;  4QEO A;  4QEN A;  3CBP A;  5EX3 A;  3MO0 A;  1ZKK A;  4J8O A;  5CCM A;  1MVX A;  4C1Q A;  4YND A;  1N3J A;  2R3A A;  5TTF A;  3M53 A;  3M54 A;  2IGQ A;  5ARF A;  4JLG A;  4YPU A;  3TG5 A;  3KMJ A;  4O30 A;  4FMU A;  3OXG A;  2F69 A;  3OXL A;  5EG2 A;  4Z4P A;  3QWW A;  1H3I A;  5EX0 A;  3N71 A;  5AYF A;  3KMA A;  4JDS A;  2G46 A;  3QWP A;  1MUF A;  3S8P A;  5JIY A;  5KJK A;  3RJW A;  3RIB A;  5JJ0 A;  3RAY A;  4QEP A;  3S7D A;  3S7J A;  3M59 A;  5KJN A;  4NVQ A;  3MEK A;  3VV0 A;  5F5E A;  5T5G A;  5T0M A;  4YPA A;  3K5K A;  4H12 A;  3F9Z A;  3OPE A;  4J83 A;  3M5A A;  4MI0 A;  4NJ5 A;  3M56 A;  5CPR B;  3M58 A;  5CCL A;  3OOI A;  3RQ4 A;  5JIN A;  3OXF A;  3F9W A;  4BUP A;  5KJM A;  4J7I A;  5TEG A;  3M55 A;  3FPD A;  4IJ8 A;  3S7F A;  4O6F A;  1O9S A;  3SW9 A;  1PEG A;  3VUZ A;  3RU0 A;  4AU7 A;  5HI7 A;  1N6A A;  4YNP A;  5F6L A;  3SWC A;  2JV0 A;  4E47 A;  3EP0 A;  5JHN A;  1XQH A; 
#chains in the Genus database with same CATH homology
 3MO5 A;  4LDG A;  2RFI A;  3QWV A;  1MT6 A;  3KMT A;  5F59 A;  5TH7 A;  3OS5 A;  2W5Y A;  4YNM A;  5ARG A;  3MO2 A;  5HQ8 A;  5T0K A;  3S7B A;  3TG4 A;  4J7F A;  3F9X A;  3CBM A;  2BQZ A;  3BO5 A;  4RZ0 A;  2W5Z A;  5KJL A;  4IJD A;  1ML9 A;  5F6K C;  3DB5 A;  3CBO A;  3DAL A;  4I51 A;  3M57 A;  1MVH A;  2O8J A;  5LSX A;  1N6C A;  3F9Y A;  4YPE A;  4WUY A;  3IHX A;  3HNA A;  4MI5 A;  2QPW A;  3PDN A;  5LSZ A;  4QEO A;  4QEN A;  3CBP A;  5EX3 A;  3MO0 A;  1ZKK A;  4J8O A;  5CCM A;  1MVX A;  4C1Q A;  4YND A;  1N3J A;  2R3A A;  5TTF A;  3M53 A;  3M54 A;  2IGQ A;  5ARF A;  4JLG A;  4YPU A;  3TG5 A;  3KMJ A;  4O30 A;  4FMU A;  3OXG A;  2F69 A;  3OXL A;  5EG2 A;  4Z4P A;  3QWW A;  1H3I A;  5EX0 A;  3N71 A;  5AYF A;  3KMA A;  4JDS A;  2G46 A;  3QWP A;  1MUF A;  3S8P A;  5JIY A;  5KJK A;  3RJW A;  3RIB A;  5JJ0 A;  3RAY A;  4QEP A;  3S7D A;  3S7J A;  3M59 A;  5KJN A;  4NVQ A;  3MEK A;  3VV0 A;  5F5E A;  5T5G A;  5T0M A;  4YPA A;  3K5K A;  4H12 A;  3F9Z A;  3OPE A;  4J83 A;  3M5A A;  4MI0 A;  4NJ5 A;  3M56 A;  5CPR B;  3M58 A;  5CCL A;  3OOI A;  3RQ4 A;  5JIN A;  3OXF A;  3F9W A;  4BUP A;  5KJM A;  4J7I A;  5TEG A;  3M55 A;  3FPD A;  4IJ8 A;  3S7F A;  4O6F A;  1O9S A;  3SW9 A;  1PEG A;  3VUZ A;  3RU0 A;  4AU7 A;  5HI7 A;  1N6A A;  4YNP A;  5F6L A;  3SWC A;  2JV0 A;  4E47 A;  3EP0 A;  5JHN A;  1XQH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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