5JJ0A

Structure of g9a set-domain with histone h3k9m peptide and excess sah
Total Genus 76
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
273
structure length
273
Chain Sequence
IRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQSR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
molecule keywords Histone-lysine N-methyltransferase EHMT2
total genus 76
structure length 273
sequence length 273
chains with identical sequence B
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2016-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 5jj0A00
3OOIA 5F5EA 3S7FA 3F9XA 5JINA 5CCMA 5AYFA 5KJKA 3N71A 5JHNA 3S7DA 5ARGA 1N6AA 1O9SA 3MEKA 3F9YA 5JIYA 3S8PA 4YPEA 3TG4A 3M5AA 4J8OA 4YNDA 4IJDA 3VV0A 5KJLA 4IJ8A 2R3AA 1MVXA 3EP0A 3BO5A 5TH7A 2W5YA 4WUYA 4I51A 1ZKKA 4Z4PA 3CBPA 5HI7A 2QPWA 4QEPA 5F6LA 3KMJA 2IGQA 4JLGA 4BUPA 3CBMA 3CBOA 3K5KA 2W5ZA 4O30A 5TTFA 3MO2A 5ARFA 1ML9A 4J7FA 3F9WA 3QWPA 3RU0A 3SWCA 5F6KC 5LSXA 1MT6A 3QWWA 4QEOA 5LSZA 1XQHA 3DB5A 5HQ8A 5CCLA 3QWVA 3RQ4A 5KJMA 4QENA 5CPRB 2JV0A 5T0KA 3OS5A 4H12A 2O8JA 3KMAA 3DALA 3FPDA 3S7JA 4YPAA 3TG5A 3VUZA 3M59A 4J7IA 4E47A 5EX3A 4JDSA 3M58A 1H3IA 5EX0A 3OXFA 3PDNA 3M57A 4NJ5A 3RJWA 5T0MA 3RAYA 5JJ0A 3F9ZA 4C1QA 3MO0A 4YNMA 4LDGA 5KJNA 4MI0A 1N3JA 3M54A 3OPEA 3M56A 3IHXA 3SW9A 2G46A 3HNAA 3S7BA 5F59A 2RFIA 3RIBA 1PEGA 1MVHA 3OXLA 4FMUA 4YPUA 4O6FA 4RZ0A 4AU7A 3M53A 2BQZA 4NVQA 4YNPA 5EG2A 3KMTA 3M55A 3MO5A 4J83A 2F69A 5T5GA 4MI5A 5TEGA 3OXGA 1N6CA 1MUFA
chains in the Genus database with same CATH superfamily
3OOIA 5F5EA 3S7FA 3F9XA 5JINA 5CCMA 5AYFA 5KJKA 3N71A 5JHNA 3S7DA 5ARGA 1N6AA 1O9SA 3MEKA 3F9YA 5JIYA 3S8PA 4YPEA 3TG4A 3M5AA 4J8OA 4YNDA 4IJDA 3VV0A 5KJLA 4IJ8A 2R3AA 1MVXA 3EP0A 3BO5A 5TH7A 2W5YA 4WUYA 4I51A 1ZKKA 4Z4PA 3CBPA 5HI7A 2QPWA 4QEPA 5F6LA 3KMJA 2IGQA 4JLGA 4BUPA 3CBMA 3CBOA 3K5KA 2W5ZA 4O30A 5TTFA 3MO2A 5ARFA 1ML9A 4J7FA 3F9WA 3QWPA 3RU0A 3SWCA 5F6KC 5LSXA 1MT6A 3QWWA 4QEOA 5LSZA 1XQHA 3DB5A 5HQ8A 5CCLA 3QWVA 3RQ4A 5KJMA 4QENA 5CPRB 2JV0A 5T0KA 3OS5A 4H12A 2O8JA 3KMAA 3DALA 3FPDA 3S7JA 4YPAA 3TG5A 3VUZA 3M59A 4J7IA 4E47A 5EX3A 4JDSA 3M58A 1H3IA 5EX0A 3OXFA 3PDNA 3M57A 4NJ5A 3RJWA 5T0MA 3RAYA 5JJ0A 3F9ZA 4C1QA 3MO0A 4YNMA 4LDGA 5KJNA 4MI0A 1N3JA 3M54A 3OPEA 3M56A 3IHXA 3SW9A 2G46A 3HNAA 3S7BA 5F59A 2RFIA 3RIBA 1PEGA 1MVHA 3OXLA 4FMUA 4YPUA 4O6FA 4RZ0A 4AU7A 3M53A 2BQZA 4NVQA 4YNPA 5EG2A 3KMTA 3M55A 3MO5A 4J83A 2F69A 5T5GA 4MI5A 5TEGA 3OXGA 1N6CA 1MUFA
chains in the Genus database with same CATH topology
3OOIA 5F5EA 3S7FA 3F9XA 5JINA 5CCMA 5AYFA 5KJKA 3N71A 5JHNA 3S7DA 5ARGA 1N6AA 1O9SA 3MEKA 3F9YA 5JIYA 3S8PA 4YPEA 3TG4A 3M5AA 4J8OA 4YNDA 4IJDA 3VV0A 5KJLA 4IJ8A 2R3AA 1MVXA 3EP0A 3BO5A 5TH7A 2W5YA 4WUYA 4I51A 1ZKKA 4Z4PA 3CBPA 5HI7A 2QPWA 4QEPA 5F6LA 3KMJA 2IGQA 4JLGA 4BUPA 3CBMA 3CBOA 3K5KA 2W5ZA 4O30A 5TTFA 3MO2A 5ARFA 1ML9A 4J7FA 3F9WA 3QWPA 3RU0A 3SWCA 5F6KC 5LSXA 1MT6A 3QWWA 4QEOA 5LSZA 1XQHA 3DB5A 5HQ8A 5CCLA 3QWVA 3RQ4A 5KJMA 4QENA 5CPRB 2JV0A 5T0KA 3OS5A 4H12A 2O8JA 3KMAA 3DALA 3FPDA 3S7JA 4YPAA 3TG5A 3VUZA 3M59A 4J7IA 4E47A 5EX3A 4JDSA 3M58A 1H3IA 5EX0A 3OXFA 3PDNA 3M57A 4NJ5A 3RJWA 5T0MA 3RAYA 5JJ0A 3F9ZA 4C1QA 3MO0A 4YNMA 4LDGA 5KJNA 4MI0A 1N3JA 3M54A 3OPEA 3M56A 3IHXA 3SW9A 2G46A 3HNAA 3S7BA 5F59A 2RFIA 3RIBA 1PEGA 1MVHA 3OXLA 4FMUA 4YPUA 4O6FA 4RZ0A 4AU7A 3M53A 2BQZA 4NVQA 4YNPA 5EG2A 3KMTA 3M55A 3MO5A 4J83A 2F69A 5T5GA 4MI5A 5TEGA 3OXGA 1N6CA 1MUFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OOI A;  5F5E A;  3S7F A;  3F9X A;  5JIN A;  5CCM A;  5AYF A;  5KJK A;  3N71 A;  5JHN A;  3S7D A;  5ARG A;  1N6A A;  1O9S A;  3MEK A;  3F9Y A;  5JIY A;  3S8P A;  4YPE A;  3TG4 A;  3M5A A;  4J8O A;  4YND A;  4IJD A;  3VV0 A;  5KJL A;  4IJ8 A;  2R3A A;  1MVX A;  3EP0 A;  3BO5 A;  5TH7 A;  2W5Y A;  4WUY A;  4I51 A;  1ZKK A;  4Z4P A;  3CBP A;  5HI7 A;  2QPW A;  4QEP A;  5F6L A;  3KMJ A;  2IGQ A;  4JLG A;  4BUP A;  3CBM A;  3CBO A;  3K5K A;  2W5Z A;  4O30 A;  5TTF A;  3MO2 A;  5ARF A;  1ML9 A;  4J7F A;  3F9W A;  3QWP A;  3RU0 A;  3SWC A;  5F6K C;  5LSX A;  1MT6 A;  3QWW A;  4QEO A;  5LSZ A;  1XQH A;  3DB5 A;  5HQ8 A;  5CCL A;  3QWV A;  3RQ4 A;  5KJM A;  4QEN A;  5CPR B;  2JV0 A;  5T0K A;  3OS5 A;  4H12 A;  2O8J A;  3KMA A;  3DAL A;  3FPD A;  3S7J A;  4YPA A;  3TG5 A;  3VUZ A;  3M59 A;  4J7I A;  4E47 A;  5EX3 A;  4JDS A;  3M58 A;  1H3I A;  5EX0 A;  3OXF A;  3PDN A;  3M57 A;  4NJ5 A;  3RJW A;  5T0M A;  3RAY A;  5JJ0 A;  3F9Z A;  4C1Q A;  3MO0 A;  4YNM A;  4LDG A;  5KJN A;  4MI0 A;  1N3J A;  3M54 A;  3OPE A;  3M56 A;  3IHX A;  3SW9 A;  2G46 A;  3HNA A;  3S7B A;  5F59 A;  2RFI A;  3RIB A;  1PEG A;  1MVH A;  3OXL A;  4FMU A;  4YPU A;  4O6F A;  4RZ0 A;  4AU7 A;  3M53 A;  2BQZ A;  4NVQ A;  4YNP A;  5EG2 A;  3KMT A;  3M55 A;  3MO5 A;  4J83 A;  2F69 A;  5T5G A;  4MI5 A;  5TEG A;  3OXG A;  1N6C A;  1MUF A; 
#chains in the Genus database with same CATH topology
 3OOI A;  5F5E A;  3S7F A;  3F9X A;  5JIN A;  5CCM A;  5AYF A;  5KJK A;  3N71 A;  5JHN A;  3S7D A;  5ARG A;  1N6A A;  1O9S A;  3MEK A;  3F9Y A;  5JIY A;  3S8P A;  4YPE A;  3TG4 A;  3M5A A;  4J8O A;  4YND A;  4IJD A;  3VV0 A;  5KJL A;  4IJ8 A;  2R3A A;  1MVX A;  3EP0 A;  3BO5 A;  5TH7 A;  2W5Y A;  4WUY A;  4I51 A;  1ZKK A;  4Z4P A;  3CBP A;  5HI7 A;  2QPW A;  4QEP A;  5F6L A;  3KMJ A;  2IGQ A;  4JLG A;  4BUP A;  3CBM A;  3CBO A;  3K5K A;  2W5Z A;  4O30 A;  5TTF A;  3MO2 A;  5ARF A;  1ML9 A;  4J7F A;  3F9W A;  3QWP A;  3RU0 A;  3SWC A;  5F6K C;  5LSX A;  1MT6 A;  3QWW A;  4QEO A;  5LSZ A;  1XQH A;  3DB5 A;  5HQ8 A;  5CCL A;  3QWV A;  3RQ4 A;  5KJM A;  4QEN A;  5CPR B;  2JV0 A;  5T0K A;  3OS5 A;  4H12 A;  2O8J A;  3KMA A;  3DAL A;  3FPD A;  3S7J A;  4YPA A;  3TG5 A;  3VUZ A;  3M59 A;  4J7I A;  4E47 A;  5EX3 A;  4JDS A;  3M58 A;  1H3I A;  5EX0 A;  3OXF A;  3PDN A;  3M57 A;  4NJ5 A;  3RJW A;  5T0M A;  3RAY A;  5JJ0 A;  3F9Z A;  4C1Q A;  3MO0 A;  4YNM A;  4LDG A;  5KJN A;  4MI0 A;  1N3J A;  3M54 A;  3OPE A;  3M56 A;  3IHX A;  3SW9 A;  2G46 A;  3HNA A;  3S7B A;  5F59 A;  2RFI A;  3RIB A;  1PEG A;  1MVH A;  3OXL A;  4FMU A;  4YPU A;  4O6F A;  4RZ0 A;  4AU7 A;  3M53 A;  2BQZ A;  4NVQ A;  4YNP A;  5EG2 A;  3KMT A;  3M55 A;  3MO5 A;  4J83 A;  2F69 A;  5T5G A;  4MI5 A;  5TEG A;  3OXG A;  1N6C A;  1MUF A; 
#chains in the Genus database with same CATH homology
 3OOI A;  5F5E A;  3S7F A;  3F9X A;  5JIN A;  5CCM A;  5AYF A;  5KJK A;  3N71 A;  5JHN A;  3S7D A;  5ARG A;  1N6A A;  1O9S A;  3MEK A;  3F9Y A;  5JIY A;  3S8P A;  4YPE A;  3TG4 A;  3M5A A;  4J8O A;  4YND A;  4IJD A;  3VV0 A;  5KJL A;  4IJ8 A;  2R3A A;  1MVX A;  3EP0 A;  3BO5 A;  5TH7 A;  2W5Y A;  4WUY A;  4I51 A;  1ZKK A;  4Z4P A;  3CBP A;  5HI7 A;  2QPW A;  4QEP A;  5F6L A;  3KMJ A;  2IGQ A;  4JLG A;  4BUP A;  3CBM A;  3CBO A;  3K5K A;  2W5Z A;  4O30 A;  5TTF A;  3MO2 A;  5ARF A;  1ML9 A;  4J7F A;  3F9W A;  3QWP A;  3RU0 A;  3SWC A;  5F6K C;  5LSX A;  1MT6 A;  3QWW A;  4QEO A;  5LSZ A;  1XQH A;  3DB5 A;  5HQ8 A;  5CCL A;  3QWV A;  3RQ4 A;  5KJM A;  4QEN A;  5CPR B;  2JV0 A;  5T0K A;  3OS5 A;  4H12 A;  2O8J A;  3KMA A;  3DAL A;  3FPD A;  3S7J A;  4YPA A;  3TG5 A;  3VUZ A;  3M59 A;  4J7I A;  4E47 A;  5EX3 A;  4JDS A;  3M58 A;  1H3I A;  5EX0 A;  3OXF A;  3PDN A;  3M57 A;  4NJ5 A;  3RJW A;  5T0M A;  3RAY A;  5JJ0 A;  3F9Z A;  4C1Q A;  3MO0 A;  4YNM A;  4LDG A;  5KJN A;  4MI0 A;  1N3J A;  3M54 A;  3OPE A;  3M56 A;  3IHX A;  3SW9 A;  2G46 A;  3HNA A;  3S7B A;  5F59 A;  2RFI A;  3RIB A;  1PEG A;  1MVH A;  3OXL A;  4FMU A;  4YPU A;  4O6F A;  4RZ0 A;  4AU7 A;  3M53 A;  2BQZ A;  4NVQ A;  4YNP A;  5EG2 A;  3KMT A;  3M55 A;  3MO5 A;  4J83 A;  2F69 A;  5T5G A;  4MI5 A;  5TEG A;  3OXG A;  1N6C A;  1MUF A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...