1PEGA

Structural basis for the product specificity of histone lysine methyltransferases
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
293
structure length
266
Chain Sequence
b'LPISIVNREDDAFLNPNFRFIDHSIIGKNVPVADQSFRVGCSCASDEECMYSTCQCLDEMAPDPYTRKKRFAYYSQGAKKGLLRDRVLQSQEPIYECHQGCACSKDCPNRVVERGRTVPLQIFRTKDRGWGVKCPVNIKRGQFVDRYLGEIITSEEADRRRAESTIARRKDVYLFALDKFSDPDSLDPLLAGPLEVDGEYMSGPTRFINHSCDPNMAIFARVGDHADKHIHDLALFAIKDIPKGTELTFDYVNCLCGTAKCRGYLW'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords histone H3 methyltransferase DIM-5
molecule tags Transferase
source organism Neurospora crassa
publication title Structural basis for the product specificity of histone lysine methyltransferases
pubmed doi rcsb
total genus 44
structure length 266
sequence length 293
chains with identical sequence B
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2003-05-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1pegA00
3RU0A 3OXLA 4YNPA 2IGQA 5KJKA 4FMUA 4NJ5A 5JHNA 2JV0A 5F6LA 3FPDA 5CCLA 3QWPA 4J83A 4MI5A 3M59A 3SWCA 5TTFA 1H3IA 3EP0A 3OOIA 4LDGA 3M54A 3TG5A 5T5GA 5TEGA 3S7FA 3CBOA 4YPAA 2W5YA 3TG4A 4YNMA 3F9YA 4QEOA 3VUZA 3BO5A 5HI7A 5JJ0A 3MEKA 3M53A 3S8PA 4QENA 5T0MA 2RFIA 5F5EA 4MI0A 3QWVA 3RJWA 1N3JA 1MUFA 1PEGA 2F69A 1ML9A 4AU7A 3S7BA 3KMJA 3DALA 1ZKKA 5KJNA 1XQHA 5LSXA 3RQ4A 3M58A 3IHXA 4NVQA 3OXGA 3OXFA 5ARFA 1MT6A 5EX3A 3MO0A 2G46A 5T0KA 4E47A 5AYFA 4J7FA 1O9SA 4H12A 3CBPA 1MVHA 3CBMA 3MO5A 3OPEA 3PDNA 4J8OA 4RZ0A 4JDSA 4YNDA 5LSZA 3VV0A 5EX0A 3N71A 3MO2A 4I51A 3M55A 3QWWA 4IJDA 5F59A 1N6AA 3RIBA 4O6FA 4Z4PA 5JINA 2QPWA 4WUYA 2W5ZA 3KMTA 3M5AA 4YPUA 5CPRB 3M56A 5TH7A 5CCMA 3RAYA 3KMAA 3S7JA 5JIYA 2O8JA 3F9ZA 4BUPA 5HQ8A 3SW9A 5ARGA 3DB5A 1N6CA 3OS5A 3HNAA 4IJ8A 2BQZA 4QEPA 3F9WA 4JLGA 3F9XA 5F6KC 5KJMA 5EG2A 3K5KA 4YPEA 2R3AA 1MVXA 5KJLA 3S7DA 3M57A 4O30A 4C1QA 4J7IA
chains in the Genus database with same CATH superfamily
3RU0A 3OXLA 4YNPA 2IGQA 5KJKA 4FMUA 4NJ5A 5JHNA 2JV0A 5F6LA 3FPDA 5CCLA 3QWPA 4J83A 4MI5A 3M59A 3SWCA 5TTFA 1H3IA 3EP0A 3OOIA 4LDGA 3M54A 3TG5A 5T5GA 5TEGA 3S7FA 3CBOA 4YPAA 2W5YA 3TG4A 4YNMA 3F9YA 4QEOA 3VUZA 3BO5A 5HI7A 5JJ0A 3MEKA 3M53A 3S8PA 4QENA 5T0MA 2RFIA 5F5EA 4MI0A 3QWVA 3RJWA 1N3JA 1MUFA 1PEGA 2F69A 1ML9A 4AU7A 3S7BA 3KMJA 3DALA 1ZKKA 5KJNA 1XQHA 5LSXA 3RQ4A 3M58A 3IHXA 4NVQA 3OXGA 3OXFA 5ARFA 1MT6A 5EX3A 3MO0A 2G46A 5T0KA 4E47A 5AYFA 4J7FA 1O9SA 4H12A 3CBPA 1MVHA 3CBMA 3MO5A 3OPEA 3PDNA 4J8OA 4RZ0A 4JDSA 4YNDA 5LSZA 3VV0A 5EX0A 3N71A 3MO2A 4I51A 3M55A 3QWWA 4IJDA 5F59A 1N6AA 3RIBA 4O6FA 4Z4PA 5JINA 2QPWA 4WUYA 2W5ZA 3KMTA 3M5AA 4YPUA 5CPRB 3M56A 5TH7A 5CCMA 3RAYA 3KMAA 3S7JA 5JIYA 2O8JA 3F9ZA 4BUPA 5HQ8A 3SW9A 5ARGA 3DB5A 1N6CA 3OS5A 3HNAA 4IJ8A 2BQZA 4QEPA 3F9WA 4JLGA 3F9XA 5F6KC 5KJMA 5EG2A 3K5KA 4YPEA 2R3AA 1MVXA 5KJLA 3S7DA 3M57A 4O30A 4C1QA 4J7IA
chains in the Genus database with same CATH topology
3RU0A 3OXLA 4YNPA 2IGQA 5KJKA 4FMUA 4NJ5A 5JHNA 2JV0A 5F6LA 3FPDA 5CCLA 3QWPA 4J83A 4MI5A 3M59A 3SWCA 5TTFA 1H3IA 3EP0A 3OOIA 4LDGA 3M54A 3TG5A 5T5GA 5TEGA 3S7FA 3CBOA 4YPAA 2W5YA 3TG4A 4YNMA 3F9YA 4QEOA 3VUZA 3BO5A 5HI7A 5JJ0A 3MEKA 3M53A 3S8PA 4QENA 5T0MA 2RFIA 5F5EA 4MI0A 3QWVA 3RJWA 1N3JA 1MUFA 1PEGA 2F69A 1ML9A 4AU7A 3S7BA 3KMJA 3DALA 1ZKKA 5KJNA 1XQHA 5LSXA 3RQ4A 3M58A 3IHXA 4NVQA 3OXGA 3OXFA 5ARFA 1MT6A 5EX3A 3MO0A 2G46A 5T0KA 4E47A 5AYFA 4J7FA 1O9SA 4H12A 3CBPA 1MVHA 3CBMA 3MO5A 3OPEA 3PDNA 4J8OA 4RZ0A 4JDSA 4YNDA 5LSZA 3VV0A 5EX0A 3N71A 3MO2A 4I51A 3M55A 3QWWA 4IJDA 5F59A 1N6AA 3RIBA 4O6FA 4Z4PA 5JINA 2QPWA 4WUYA 2W5ZA 3KMTA 3M5AA 4YPUA 5CPRB 3M56A 5TH7A 5CCMA 3RAYA 3KMAA 3S7JA 5JIYA 2O8JA 3F9ZA 4BUPA 5HQ8A 3SW9A 5ARGA 3DB5A 1N6CA 3OS5A 3HNAA 4IJ8A 2BQZA 4QEPA 3F9WA 4JLGA 3F9XA 5F6KC 5KJMA 5EG2A 3K5KA 4YPEA 2R3AA 1MVXA 5KJLA 3S7DA 3M57A 4O30A 4C1QA 4J7IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RU0 A;  3OXL A;  4YNP A;  2IGQ A;  5KJK A;  4FMU A;  4NJ5 A;  5JHN A;  2JV0 A;  5F6L A;  3FPD A;  5CCL A;  3QWP A;  4J83 A;  4MI5 A;  3M59 A;  3SWC A;  5TTF A;  1H3I A;  3EP0 A;  3OOI A;  4LDG A;  3M54 A;  3TG5 A;  5T5G A;  5TEG A;  3S7F A;  3CBO A;  4YPA A;  2W5Y A;  3TG4 A;  4YNM A;  3F9Y A;  4QEO A;  3VUZ A;  3BO5 A;  5HI7 A;  5JJ0 A;  3MEK A;  3M53 A;  3S8P A;  4QEN A;  5T0M A;  2RFI A;  5F5E A;  4MI0 A;  3QWV A;  3RJW A;  1N3J A;  1MUF A;  1PEG A;  2F69 A;  1ML9 A;  4AU7 A;  3S7B A;  3KMJ A;  3DAL A;  1ZKK A;  5KJN A;  1XQH A;  5LSX A;  3RQ4 A;  3M58 A;  3IHX A;  4NVQ A;  3OXG A;  3OXF A;  5ARF A;  1MT6 A;  5EX3 A;  3MO0 A;  2G46 A;  5T0K A;  4E47 A;  5AYF A;  4J7F A;  1O9S A;  4H12 A;  3CBP A;  1MVH A;  3CBM A;  3MO5 A;  3OPE A;  3PDN A;  4J8O A;  4RZ0 A;  4JDS A;  4YND A;  5LSZ A;  3VV0 A;  5EX0 A;  3N71 A;  3MO2 A;  4I51 A;  3M55 A;  3QWW A;  4IJD A;  5F59 A;  1N6A A;  3RIB A;  4O6F A;  4Z4P A;  5JIN A;  2QPW A;  4WUY A;  2W5Z A;  3KMT A;  3M5A A;  4YPU A;  5CPR B;  3M56 A;  5TH7 A;  5CCM A;  3RAY A;  3KMA A;  3S7J A;  5JIY A;  2O8J A;  3F9Z A;  4BUP A;  5HQ8 A;  3SW9 A;  5ARG A;  3DB5 A;  1N6C A;  3OS5 A;  3HNA A;  4IJ8 A;  2BQZ A;  4QEP A;  3F9W A;  4JLG A;  3F9X A;  5F6K C;  5KJM A;  5EG2 A;  3K5K A;  4YPE A;  2R3A A;  1MVX A;  5KJL A;  3S7D A;  3M57 A;  4O30 A;  4C1Q A;  4J7I A; 
#chains in the Genus database with same CATH topology
 3RU0 A;  3OXL A;  4YNP A;  2IGQ A;  5KJK A;  4FMU A;  4NJ5 A;  5JHN A;  2JV0 A;  5F6L A;  3FPD A;  5CCL A;  3QWP A;  4J83 A;  4MI5 A;  3M59 A;  3SWC A;  5TTF A;  1H3I A;  3EP0 A;  3OOI A;  4LDG A;  3M54 A;  3TG5 A;  5T5G A;  5TEG A;  3S7F A;  3CBO A;  4YPA A;  2W5Y A;  3TG4 A;  4YNM A;  3F9Y A;  4QEO A;  3VUZ A;  3BO5 A;  5HI7 A;  5JJ0 A;  3MEK A;  3M53 A;  3S8P A;  4QEN A;  5T0M A;  2RFI A;  5F5E A;  4MI0 A;  3QWV A;  3RJW A;  1N3J A;  1MUF A;  1PEG A;  2F69 A;  1ML9 A;  4AU7 A;  3S7B A;  3KMJ A;  3DAL A;  1ZKK A;  5KJN A;  1XQH A;  5LSX A;  3RQ4 A;  3M58 A;  3IHX A;  4NVQ A;  3OXG A;  3OXF A;  5ARF A;  1MT6 A;  5EX3 A;  3MO0 A;  2G46 A;  5T0K A;  4E47 A;  5AYF A;  4J7F A;  1O9S A;  4H12 A;  3CBP A;  1MVH A;  3CBM A;  3MO5 A;  3OPE A;  3PDN A;  4J8O A;  4RZ0 A;  4JDS A;  4YND A;  5LSZ A;  3VV0 A;  5EX0 A;  3N71 A;  3MO2 A;  4I51 A;  3M55 A;  3QWW A;  4IJD A;  5F59 A;  1N6A A;  3RIB A;  4O6F A;  4Z4P A;  5JIN A;  2QPW A;  4WUY A;  2W5Z A;  3KMT A;  3M5A A;  4YPU A;  5CPR B;  3M56 A;  5TH7 A;  5CCM A;  3RAY A;  3KMA A;  3S7J A;  5JIY A;  2O8J A;  3F9Z A;  4BUP A;  5HQ8 A;  3SW9 A;  5ARG A;  3DB5 A;  1N6C A;  3OS5 A;  3HNA A;  4IJ8 A;  2BQZ A;  4QEP A;  3F9W A;  4JLG A;  3F9X A;  5F6K C;  5KJM A;  5EG2 A;  3K5K A;  4YPE A;  2R3A A;  1MVX A;  5KJL A;  3S7D A;  3M57 A;  4O30 A;  4C1Q A;  4J7I A; 
#chains in the Genus database with same CATH homology
 3RU0 A;  3OXL A;  4YNP A;  2IGQ A;  5KJK A;  4FMU A;  4NJ5 A;  5JHN A;  2JV0 A;  5F6L A;  3FPD A;  5CCL A;  3QWP A;  4J83 A;  4MI5 A;  3M59 A;  3SWC A;  5TTF A;  1H3I A;  3EP0 A;  3OOI A;  4LDG A;  3M54 A;  3TG5 A;  5T5G A;  5TEG A;  3S7F A;  3CBO A;  4YPA A;  2W5Y A;  3TG4 A;  4YNM A;  3F9Y A;  4QEO A;  3VUZ A;  3BO5 A;  5HI7 A;  5JJ0 A;  3MEK A;  3M53 A;  3S8P A;  4QEN A;  5T0M A;  2RFI A;  5F5E A;  4MI0 A;  3QWV A;  3RJW A;  1N3J A;  1MUF A;  1PEG A;  2F69 A;  1ML9 A;  4AU7 A;  3S7B A;  3KMJ A;  3DAL A;  1ZKK A;  5KJN A;  1XQH A;  5LSX A;  3RQ4 A;  3M58 A;  3IHX A;  4NVQ A;  3OXG A;  3OXF A;  5ARF A;  1MT6 A;  5EX3 A;  3MO0 A;  2G46 A;  5T0K A;  4E47 A;  5AYF A;  4J7F A;  1O9S A;  4H12 A;  3CBP A;  1MVH A;  3CBM A;  3MO5 A;  3OPE A;  3PDN A;  4J8O A;  4RZ0 A;  4JDS A;  4YND A;  5LSZ A;  3VV0 A;  5EX0 A;  3N71 A;  3MO2 A;  4I51 A;  3M55 A;  3QWW A;  4IJD A;  5F59 A;  1N6A A;  3RIB A;  4O6F A;  4Z4P A;  5JIN A;  2QPW A;  4WUY A;  2W5Z A;  3KMT A;  3M5A A;  4YPU A;  5CPR B;  3M56 A;  5TH7 A;  5CCM A;  3RAY A;  3KMA A;  3S7J A;  5JIY A;  2O8J A;  3F9Z A;  4BUP A;  5HQ8 A;  3SW9 A;  5ARG A;  3DB5 A;  1N6C A;  3OS5 A;  3HNA A;  4IJ8 A;  2BQZ A;  4QEP A;  3F9W A;  4JLG A;  3F9X A;  5F6K C;  5KJM A;  5EG2 A;  3K5K A;  4YPE A;  2R3A A;  1MVX A;  5KJL A;  3S7D A;  3M57 A;  4O30 A;  4C1Q A;  4J7I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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