1MT6A

Structure of histone h3 k4-specific methyltransferase set7/9 with adohcy
Total Genus 62
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
280
structure length
280
Chain Sequence
TLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The active site of the SET domain is constructed on a knot
pubmed rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords SET9
total genus 62
structure length 280
sequence length 280
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF02493 MORN MORN repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.110.10 Mainly Beta Single Sheet Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 1mt6A01
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1mt6A02
4C1QA 2QPWA 3KMAA 4IJDA 2G46A 5F5EA 3S7FA 4NVQA 3FPDA 4QEOA 4FMUA 3DB5A 1MVHA 3F9ZA 5F6KC 3OXFA 4YNDA 5ARGA 3QWPA 3SW9A 1XQHA 2R3AA 5T0MA 4RZ0A 4O6FA 4QENA 1N3JA 4I51A 4Z4PA 4O30A 5JIYA 3S8PA 2W5YA 3MEKA 4JLGA 5KJMA 5CPRB 4QEPA 5JJ0A 1MT6A 5JHNA 3BO5A 4YPEA 3TG4A 2BQZA 5HQ8A 2RFIA 3CBPA 5TH7A 5LSXA 3DALA 3KMJA 4MI0A 5CCMA 5TTFA 3MO0A 4NJ5A 1MUFA 3CBMA 5ARFA 2IGQA 4WUYA 3VV0A 3KMTA 5F59A 3M54A 3M55A 1H3IA 3F9WA 3SWCA 3M56A 5JINA 1O9SA 3RJWA 3CBOA 4MI5A 3S7DA 4J8OA 3OS5A 3PDNA 5T0KA 5F6LA 1ML9A 3M57A 4BUPA 3MO2A 5EX0A 3N71A 1N6CA 3MO5A 3OXGA 1ZKKA 3S7JA 3OOIA 3HNAA 3RAYA 5T5GA 3RQ4A 5KJKA 5TEGA 5EG2A 4JDSA 1MVXA 3VUZA 5EX3A 4IJ8A 4LDGA 3M5AA 5HI7A 4AU7A 5KJNA 3F9XA 3OPEA 5CCLA 2F69A 3EP0A 5LSZA 3RU0A 3RIBA 3M59A 4YNMA 5KJLA 4J83A 3M53A 3QWWA 5AYFA 2W5ZA 2JV0A 1PEGA 4J7FA 3S7BA 3F9YA 3TG5A 3IHXA 3OXLA 4H12A 3K5KA 4J7IA 2O8JA 4YNPA 4YPUA 3M58A 4YPAA 3QWVA 4E47A 1N6AA
chains in the Genus database with same CATH superfamily
4C1QA 2QPWA 3KMAA 4IJDA 2G46A 5F5EA 3S7FA 4NVQA 3FPDA 4QEOA 4FMUA 3DB5A 1MVHA 3F9ZA 5F6KC 3OXFA 4YNDA 5ARGA 3QWPA 3SW9A 1XQHA 2R3AA 5T0MA 4RZ0A 4O6FA 4QENA 1N3JA 4I51A 4Z4PA 4O30A 5JIYA 3S8PA 2W5YA 3MEKA 4JLGA 5KJMA 5CPRB 4QEPA 5JJ0A 1MT6A 5JHNA 3BO5A 4YPEA 3TG4A 2BQZA 5HQ8A 2RFIA 3CBPA 5TH7A 5LSXA 3DALA 3KMJA 4MI0A 5CCMA 5TTFA 3MO0A 4NJ5A 1MUFA 3CBMA 5ARFA 2IGQA 4WUYA 3VV0A 3KMTA 5F59A 3M54A 3M55A 1H3IA 3F9WA 3SWCA 3M56A 5JINA 1O9SA 3RJWA 3CBOA 4MI5A 3S7DA 4J8OA 3OS5A 3PDNA 5T0KA 5F6LA 1ML9A 3M57A 4BUPA 3MO2A 5EX0A 3N71A 1N6CA 3MO5A 3OXGA 1ZKKA 3S7JA 3OOIA 3HNAA 3RAYA 5T5GA 3RQ4A 5KJKA 5TEGA 5EG2A 4JDSA 1MVXA 3VUZA 5EX3A 4IJ8A 4LDGA 3M5AA 5HI7A 4AU7A 5KJNA 3F9XA 3OPEA 5CCLA 2F69A 3EP0A 5LSZA 3RU0A 3RIBA 3M59A 4YNMA 5KJLA 4J83A 3M53A 3QWWA 5AYFA 2W5ZA 2JV0A 1PEGA 4J7FA 3S7BA 3F9YA 3TG5A 3IHXA 3OXLA 4H12A 3K5KA 4J7IA 2O8JA 4YNPA 4YPUA 3M58A 4YPAA 3QWVA 4E47A 1N6AA
chains in the Genus database with same CATH topology
4C1QA 2QPWA 3KMAA 4IJDA 2G46A 5F5EA 3S7FA 4NVQA 3FPDA 4QEOA 4FMUA 3DB5A 1MVHA 3F9ZA 5F6KC 3OXFA 4YNDA 5ARGA 3QWPA 3SW9A 1XQHA 2R3AA 5T0MA 4RZ0A 4O6FA 4QENA 1N3JA 4I51A 4Z4PA 4O30A 5JIYA 3S8PA 2W5YA 3MEKA 4JLGA 5KJMA 5CPRB 4QEPA 5JJ0A 1MT6A 5JHNA 3BO5A 4YPEA 3TG4A 2BQZA 5HQ8A 2RFIA 3CBPA 5TH7A 5LSXA 3DALA 3KMJA 4MI0A 5CCMA 5TTFA 3MO0A 4NJ5A 1MUFA 3CBMA 5ARFA 2IGQA 4WUYA 3VV0A 3KMTA 5F59A 3M54A 3M55A 1H3IA 3F9WA 3SWCA 3M56A 5JINA 1O9SA 3RJWA 3CBOA 4MI5A 3S7DA 4J8OA 3OS5A 3PDNA 5T0KA 5F6LA 1ML9A 3M57A 4BUPA 3MO2A 5EX0A 3N71A 1N6CA 3MO5A 3OXGA 1ZKKA 3S7JA 3OOIA 3HNAA 3RAYA 5T5GA 3RQ4A 5KJKA 5TEGA 5EG2A 4JDSA 1MVXA 3VUZA 5EX3A 4IJ8A 4LDGA 3M5AA 5HI7A 4AU7A 5KJNA 3F9XA 3OPEA 5CCLA 2F69A 3EP0A 5LSZA 3RU0A 3RIBA 3M59A 4YNMA 5KJLA 4J83A 3M53A 3QWWA 5AYFA 2W5ZA 2JV0A 1PEGA 4J7FA 3S7BA 3F9YA 3TG5A 3IHXA 3OXLA 4H12A 3K5KA 4J7IA 2O8JA 4YNPA 4YPUA 3M58A 4YPAA 3QWVA 4E47A 1N6AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C1Q A;  2QPW A;  3KMA A;  4IJD A;  2G46 A;  5F5E A;  3S7F A;  4NVQ A;  3FPD A;  4QEO A;  4FMU A;  3DB5 A;  1MVH A;  3F9Z A;  5F6K C;  3OXF A;  4YND A;  5ARG A;  3QWP A;  3SW9 A;  1XQH A;  2R3A A;  5T0M A;  4RZ0 A;  4O6F A;  4QEN A;  1N3J A;  4I51 A;  4Z4P A;  4O30 A;  5JIY A;  3S8P A;  2W5Y A;  3MEK A;  4JLG A;  5KJM A;  5CPR B;  4QEP A;  5JJ0 A;  1MT6 A;  5JHN A;  3BO5 A;  4YPE A;  3TG4 A;  2BQZ A;  5HQ8 A;  2RFI A;  3CBP A;  5TH7 A;  5LSX A;  3DAL A;  3KMJ A;  4MI0 A;  5CCM A;  5TTF A;  3MO0 A;  4NJ5 A;  1MUF A;  3CBM A;  5ARF A;  2IGQ A;  4WUY A;  3VV0 A;  3KMT A;  5F59 A;  3M54 A;  3M55 A;  1H3I A;  3F9W A;  3SWC A;  3M56 A;  5JIN A;  1O9S A;  3RJW A;  3CBO A;  4MI5 A;  3S7D A;  4J8O A;  3OS5 A;  3PDN A;  5T0K A;  5F6L A;  1ML9 A;  3M57 A;  4BUP A;  3MO2 A;  5EX0 A;  3N71 A;  1N6C A;  3MO5 A;  3OXG A;  1ZKK A;  3S7J A;  3OOI A;  3HNA A;  3RAY A;  5T5G A;  3RQ4 A;  5KJK A;  5TEG A;  5EG2 A;  4JDS A;  1MVX A;  3VUZ A;  5EX3 A;  4IJ8 A;  4LDG A;  3M5A A;  5HI7 A;  4AU7 A;  5KJN A;  3F9X A;  3OPE A;  5CCL A;  2F69 A;  3EP0 A;  5LSZ A;  3RU0 A;  3RIB A;  3M59 A;  4YNM A;  5KJL A;  4J83 A;  3M53 A;  3QWW A;  5AYF A;  2W5Z A;  2JV0 A;  1PEG A;  4J7F A;  3S7B A;  3F9Y A;  3TG5 A;  3IHX A;  3OXL A;  4H12 A;  3K5K A;  4J7I A;  2O8J A;  4YNP A;  4YPU A;  3M58 A;  4YPA A;  3QWV A;  4E47 A;  1N6A A; 
#chains in the Genus database with same CATH topology
 4C1Q A;  2QPW A;  3KMA A;  4IJD A;  2G46 A;  5F5E A;  3S7F A;  4NVQ A;  3FPD A;  4QEO A;  4FMU A;  3DB5 A;  1MVH A;  3F9Z A;  5F6K C;  3OXF A;  4YND A;  5ARG A;  3QWP A;  3SW9 A;  1XQH A;  2R3A A;  5T0M A;  4RZ0 A;  4O6F A;  4QEN A;  1N3J A;  4I51 A;  4Z4P A;  4O30 A;  5JIY A;  3S8P A;  2W5Y A;  3MEK A;  4JLG A;  5KJM A;  5CPR B;  4QEP A;  5JJ0 A;  1MT6 A;  5JHN A;  3BO5 A;  4YPE A;  3TG4 A;  2BQZ A;  5HQ8 A;  2RFI A;  3CBP A;  5TH7 A;  5LSX A;  3DAL A;  3KMJ A;  4MI0 A;  5CCM A;  5TTF A;  3MO0 A;  4NJ5 A;  1MUF A;  3CBM A;  5ARF A;  2IGQ A;  4WUY A;  3VV0 A;  3KMT A;  5F59 A;  3M54 A;  3M55 A;  1H3I A;  3F9W A;  3SWC A;  3M56 A;  5JIN A;  1O9S A;  3RJW A;  3CBO A;  4MI5 A;  3S7D A;  4J8O A;  3OS5 A;  3PDN A;  5T0K A;  5F6L A;  1ML9 A;  3M57 A;  4BUP A;  3MO2 A;  5EX0 A;  3N71 A;  1N6C A;  3MO5 A;  3OXG A;  1ZKK A;  3S7J A;  3OOI A;  3HNA A;  3RAY A;  5T5G A;  3RQ4 A;  5KJK A;  5TEG A;  5EG2 A;  4JDS A;  1MVX A;  3VUZ A;  5EX3 A;  4IJ8 A;  4LDG A;  3M5A A;  5HI7 A;  4AU7 A;  5KJN A;  3F9X A;  3OPE A;  5CCL A;  2F69 A;  3EP0 A;  5LSZ A;  3RU0 A;  3RIB A;  3M59 A;  4YNM A;  5KJL A;  4J83 A;  3M53 A;  3QWW A;  5AYF A;  2W5Z A;  2JV0 A;  1PEG A;  4J7F A;  3S7B A;  3F9Y A;  3TG5 A;  3IHX A;  3OXL A;  4H12 A;  3K5K A;  4J7I A;  2O8J A;  4YNP A;  4YPU A;  3M58 A;  4YPA A;  3QWV A;  4E47 A;  1N6A A; 
#chains in the Genus database with same CATH homology
 4C1Q A;  2QPW A;  3KMA A;  4IJD A;  2G46 A;  5F5E A;  3S7F A;  4NVQ A;  3FPD A;  4QEO A;  4FMU A;  3DB5 A;  1MVH A;  3F9Z A;  5F6K C;  3OXF A;  4YND A;  5ARG A;  3QWP A;  3SW9 A;  1XQH A;  2R3A A;  5T0M A;  4RZ0 A;  4O6F A;  4QEN A;  1N3J A;  4I51 A;  4Z4P A;  4O30 A;  5JIY A;  3S8P A;  2W5Y A;  3MEK A;  4JLG A;  5KJM A;  5CPR B;  4QEP A;  5JJ0 A;  1MT6 A;  5JHN A;  3BO5 A;  4YPE A;  3TG4 A;  2BQZ A;  5HQ8 A;  2RFI A;  3CBP A;  5TH7 A;  5LSX A;  3DAL A;  3KMJ A;  4MI0 A;  5CCM A;  5TTF A;  3MO0 A;  4NJ5 A;  1MUF A;  3CBM A;  5ARF A;  2IGQ A;  4WUY A;  3VV0 A;  3KMT A;  5F59 A;  3M54 A;  3M55 A;  1H3I A;  3F9W A;  3SWC A;  3M56 A;  5JIN A;  1O9S A;  3RJW A;  3CBO A;  4MI5 A;  3S7D A;  4J8O A;  3OS5 A;  3PDN A;  5T0K A;  5F6L A;  1ML9 A;  3M57 A;  4BUP A;  3MO2 A;  5EX0 A;  3N71 A;  1N6C A;  3MO5 A;  3OXG A;  1ZKK A;  3S7J A;  3OOI A;  3HNA A;  3RAY A;  5T5G A;  3RQ4 A;  5KJK A;  5TEG A;  5EG2 A;  4JDS A;  1MVX A;  3VUZ A;  5EX3 A;  4IJ8 A;  4LDG A;  3M5A A;  5HI7 A;  4AU7 A;  5KJN A;  3F9X A;  3OPE A;  5CCL A;  2F69 A;  3EP0 A;  5LSZ A;  3RU0 A;  3RIB A;  3M59 A;  4YNM A;  5KJL A;  4J83 A;  3M53 A;  3QWW A;  5AYF A;  2W5Z A;  2JV0 A;  1PEG A;  4J7F A;  3S7B A;  3F9Y A;  3TG5 A;  3IHX A;  3OXL A;  4H12 A;  3K5K A;  4J7I A;  2O8J A;  4YNP A;  4YPU A;  3M58 A;  4YPA A;  3QWV A;  4E47 A;  1N6A A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...