The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
64
|
sequence length |
285
|
structure length |
283
|
Chain Sequence |
GGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYSPPGKSGPEAPEWYQVELKAFQAT
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet
pubmed doi rcsb |
| molecule keywords |
SET domain-containing protein 7
|
| molecule tags |
Transferase
|
| source organism |
Homo sapiens
|
| total genus |
64
|
| structure length |
283
|
| sequence length |
285
|
| ec nomenclature |
ec
2.1.1.43: Histone-lysine N-methyltransferase. |
| pdb deposition date | 2002-11-09 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00856 | SET | SET domain |
| A | PF02493 | MORN | MORN repeat |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Single Sheet | Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | ||
| Mainly Beta | Beta Complex | Beta-clip-like | SET domain |
#chains in the Genus database with same CATH superfamily 1MVX A; 5JIN A; 3RQ4 A; 3F9W A; 5LSX A; 5F6L A; 3FPD A; 3S8P A; 5JHN A; 5EX0 A; 5KJL A; 3F9Z A; 3OXF A; 3OOI A; 5ARF A; 4YPE A; 3IHX A; 2F69 A; 5ARG A; 5TEG A; 3SW9 A; 4J83 A; 3RAY A; 4J7I A; 3RJW A; 1H3I A; 4YNP A; 5KJN A; 5TH7 A; 3VV0 A; 5KJK A; 3DB5 A; 1ML9 A; 4WUY A; 1MUF A; 5T5G A; 3KMJ A; 4IJ8 A; 3M58 A; 4JDS A; 3S7F A; 1N3J A; 3F9Y A; 5TTF A; 4AU7 A; 1MVH A; 1XQH A; 3S7J A; 3M57 A; 3RU0 A; 2W5Y A; 3DAL A; 4NJ5 A; 3F9X A; 4QEP A; 5KJM A; 5T0M A; 1MT6 A; 4J7F A; 4RZ0 A; 3BO5 A; 3EP0 A; 3MO0 A; 2G46 A; 5T0K A; 2JV0 A; 3OPE A; 4YPA A; 3VUZ A; 3TG5 A; 2O8J A; 3QWW A; 3K5K A; 1PEG A; 5HI7 A; 2RFI A; 4H12 A; 1ZKK A; 3CBM A; 4NVQ A; 4Z4P A; 3S7B A; 3KMA A; 3MEK A; 2IGQ A; 3OXL A; 5EG2 A; 2QPW A; 4YND A; 4LDG A; 3M59 A; 4O6F A; 1N6C A; 2BQZ A; 2W5Z A; 3M56 A; 3M54 A; 4E47 A; 3KMT A; 3QWV A; 3OXG A; 4JLG A; 5F6K C; 4YPU A; 5JJ0 A; 3M5A A; 3MO2 A; 4MI0 A; 4QEO A; 4YNM A; 4QEN A; 3PDN A; 3TG4 A; 3MO5 A; 5F59 A; 4BUP A; 1N6A A; 3S7D A; 3CBO A; 4I51 A; 5AYF A; 4C1Q A; 3SWC A; 5HQ8 A; 5LSZ A; 5CCM A; 3M55 A; 4MI5 A; 4FMU A; 3QWP A; 4J8O A; 5EX3 A; 2R3A A; 4IJD A; 4O30 A; 3RIB A; 5CCL A; 3M53 A; 5JIY A; 5CPR B; 1O9S A; 3CBP A; 3N71 A; 5F5E A; 3OS5 A; 3HNA A; #chains in the Genus database with same CATH topology 1MVX A; 5JIN A; 3RQ4 A; 3F9W A; 5LSX A; 5F6L A; 3FPD A; 3S8P A; 5JHN A; 5EX0 A; 5KJL A; 3F9Z A; 3OXF A; 3OOI A; 5ARF A; 4YPE A; 3IHX A; 2F69 A; 5ARG A; 5TEG A; 3SW9 A; 4J83 A; 3RAY A; 4J7I A; 3RJW A; 1H3I A; 4YNP A; 5KJN A; 5TH7 A; 3VV0 A; 5KJK A; 3DB5 A; 1ML9 A; 4WUY A; 1MUF A; 5T5G A; 3KMJ A; 4IJ8 A; 3M58 A; 4JDS A; 3S7F A; 1N3J A; 3F9Y A; 5TTF A; 4AU7 A; 1MVH A; 1XQH A; 3S7J A; 3M57 A; 3RU0 A; 2W5Y A; 3DAL A; 4NJ5 A; 3F9X A; 4QEP A; 5KJM A; 5T0M A; 1MT6 A; 4J7F A; 4RZ0 A; 3BO5 A; 3EP0 A; 3MO0 A; 2G46 A; 5T0K A; 2JV0 A; 3OPE A; 4YPA A; 3VUZ A; 3TG5 A; 2O8J A; 3QWW A; 3K5K A; 1PEG A; 5HI7 A; 2RFI A; 4H12 A; 1ZKK A; 3CBM A; 4NVQ A; 4Z4P A; 3S7B A; 3KMA A; 3MEK A; 2IGQ A; 3OXL A; 5EG2 A; 2QPW A; 4YND A; 4LDG A; 3M59 A; 4O6F A; 1N6C A; 2BQZ A; 2W5Z A; 3M56 A; 3M54 A; 4E47 A; 3KMT A; 3QWV A; 3OXG A; 4JLG A; 5F6K C; 4YPU A; 5JJ0 A; 3M5A A; 3MO2 A; 4MI0 A; 4QEO A; 4YNM A; 4QEN A; 3PDN A; 3TG4 A; 3MO5 A; 5F59 A; 4BUP A; 1N6A A; 3S7D A; 3CBO A; 4I51 A; 5AYF A; 4C1Q A; 3SWC A; 5HQ8 A; 5LSZ A; 5CCM A; 3M55 A; 4MI5 A; 4FMU A; 3QWP A; 4J8O A; 5EX3 A; 2R3A A; 4IJD A; 4O30 A; 3RIB A; 5CCL A; 3M53 A; 5JIY A; 5CPR B; 1O9S A; 3CBP A; 3N71 A; 5F5E A; 3OS5 A; 3HNA A; #chains in the Genus database with same CATH homology 1MVX A; 5JIN A; 3RQ4 A; 3F9W A; 5LSX A; 5F6L A; 3FPD A; 3S8P A; 5JHN A; 5EX0 A; 5KJL A; 3F9Z A; 3OXF A; 3OOI A; 5ARF A; 4YPE A; 3IHX A; 2F69 A; 5ARG A; 5TEG A; 3SW9 A; 4J83 A; 3RAY A; 4J7I A; 3RJW A; 1H3I A; 4YNP A; 5KJN A; 5TH7 A; 3VV0 A; 5KJK A; 3DB5 A; 1ML9 A; 4WUY A; 1MUF A; 5T5G A; 3KMJ A; 4IJ8 A; 3M58 A; 4JDS A; 3S7F A; 1N3J A; 3F9Y A; 5TTF A; 4AU7 A; 1MVH A; 1XQH A; 3S7J A; 3M57 A; 3RU0 A; 2W5Y A; 3DAL A; 4NJ5 A; 3F9X A; 4QEP A; 5KJM A; 5T0M A; 1MT6 A; 4J7F A; 4RZ0 A; 3BO5 A; 3EP0 A; 3MO0 A; 2G46 A; 5T0K A; 2JV0 A; 3OPE A; 4YPA A; 3VUZ A; 3TG5 A; 2O8J A; 3QWW A; 3K5K A; 1PEG A; 5HI7 A; 2RFI A; 4H12 A; 1ZKK A; 3CBM A; 4NVQ A; 4Z4P A; 3S7B A; 3KMA A; 3MEK A; 2IGQ A; 3OXL A; 5EG2 A; 2QPW A; 4YND A; 4LDG A; 3M59 A; 4O6F A; 1N6C A; 2BQZ A; 2W5Z A; 3M56 A; 3M54 A; 4E47 A; 3KMT A; 3QWV A; 3OXG A; 4JLG A; 5F6K C; 4YPU A; 5JJ0 A; 3M5A A; 3MO2 A; 4MI0 A; 4QEO A; 4YNM A; 4QEN A; 3PDN A; 3TG4 A; 3MO5 A; 5F59 A; 4BUP A; 1N6A A; 3S7D A; 3CBO A; 4I51 A; 5AYF A; 4C1Q A; 3SWC A; 5HQ8 A; 5LSZ A; 5CCM A; 3M55 A; 4MI5 A; 4FMU A; 3QWP A; 4J8O A; 5EX3 A; 2R3A A; 4IJD A; 4O30 A; 3RIB A; 5CCL A; 3M53 A; 5JIY A; 5CPR B; 1O9S A; 3CBP A; 3N71 A; 5F5E A; 3OS5 A; 3HNA A;
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