1MUFA

Structure of histone h3 k4-specific methyltransferase set7/9
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
257
structure length
257
Chain Sequence
VLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The active site of the SET domain is constructed on a knot
pubmed rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords SET9
total genus 57
structure length 257
sequence length 257
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-09-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF02493 MORN MORN repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.110.10 Mainly Beta Single Sheet Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 1mufA01
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1mufA02
3F9YA 3PDNA 4J8OA 2G46A 4MI5A 4YNMA 3OS5A 4JDSA 5ARFA 5KJKA 1ZKKA 3SW9A 3KMAA 3CBOA 2R3AA 3OXLA 3OXFA 3DALA 3KMJA 3S7FA 1MT6A 1MVHA 3IHXA 3M5AA 3OOIA 5JJ0A 2F69A 3M53A 4YPUA 4O6FA 3M58A 3OXGA 4QEPA 5KJLA 2IGQA 5F6KC 1H3IA 3BO5A 3RAYA 4NVQA 3QWVA 3M54A 1MVXA 3TG5A 5CCMA 3N71A 5EX0A 5CPRB 4H12A 2RFIA 5T0MA 3S7JA 2BQZA 4Z4PA 3F9XA 4YNPA 4I51A 3M56A 3FPDA 5CCLA 5TEGA 3DB5A 4E47A 3S7DA 3F9ZA 4LDGA 5EX3A 5HI7A 3EP0A 3RU0A 4WUYA 3VUZA 4NJ5A 5AYFA 3OPEA 1XQHA 5F5EA 3MO2A 5T5GA 3SWCA 1PEGA 3K5KA 3M59A 5JINA 3CBPA 3S7BA 5F59A 5TH7A 4QEOA 3MO5A 5KJMA 4YNDA 4O30A 1O9SA 4C1QA 5EG2A 5JIYA 3RIBA 5JHNA 4J7IA 4FMUA 1ML9A 4J7FA 4JLGA 5KJNA 4AU7A 1N6AA 5LSZA 5HQ8A 3M57A 3KMTA 3QWWA 2O8JA 2QPWA 3S8PA 1N3JA 3MEKA 5F6LA 3F9WA 3CBMA 5LSXA 5ARGA 3HNAA 4QENA 5T0KA 3VV0A 4IJ8A 3RJWA 2W5YA 4J83A 4MI0A 4BUPA 5TTFA 1N6CA 4RZ0A 3TG4A 2W5ZA 3QWPA 4YPEA 4YPAA 1MUFA 2JV0A 3M55A 3MO0A 4IJDA 3RQ4A
chains in the Genus database with same CATH superfamily
3F9YA 3PDNA 4J8OA 2G46A 4MI5A 4YNMA 3OS5A 4JDSA 5ARFA 5KJKA 1ZKKA 3SW9A 3KMAA 3CBOA 2R3AA 3OXLA 3OXFA 3DALA 3KMJA 3S7FA 1MT6A 1MVHA 3IHXA 3M5AA 3OOIA 5JJ0A 2F69A 3M53A 4YPUA 4O6FA 3M58A 3OXGA 4QEPA 5KJLA 2IGQA 5F6KC 1H3IA 3BO5A 3RAYA 4NVQA 3QWVA 3M54A 1MVXA 3TG5A 5CCMA 3N71A 5EX0A 5CPRB 4H12A 2RFIA 5T0MA 3S7JA 2BQZA 4Z4PA 3F9XA 4YNPA 4I51A 3M56A 3FPDA 5CCLA 5TEGA 3DB5A 4E47A 3S7DA 3F9ZA 4LDGA 5EX3A 5HI7A 3EP0A 3RU0A 4WUYA 3VUZA 4NJ5A 5AYFA 3OPEA 1XQHA 5F5EA 3MO2A 5T5GA 3SWCA 1PEGA 3K5KA 3M59A 5JINA 3CBPA 3S7BA 5F59A 5TH7A 4QEOA 3MO5A 5KJMA 4YNDA 4O30A 1O9SA 4C1QA 5EG2A 5JIYA 3RIBA 5JHNA 4J7IA 4FMUA 1ML9A 4J7FA 4JLGA 5KJNA 4AU7A 1N6AA 5LSZA 5HQ8A 3M57A 3KMTA 3QWWA 2O8JA 2QPWA 3S8PA 1N3JA 3MEKA 5F6LA 3F9WA 3CBMA 5LSXA 5ARGA 3HNAA 4QENA 5T0KA 3VV0A 4IJ8A 3RJWA 2W5YA 4J83A 4MI0A 4BUPA 5TTFA 1N6CA 4RZ0A 3TG4A 2W5ZA 3QWPA 4YPEA 4YPAA 1MUFA 2JV0A 3M55A 3MO0A 4IJDA 3RQ4A
chains in the Genus database with same CATH topology
3F9YA 3PDNA 4J8OA 2G46A 4MI5A 4YNMA 3OS5A 4JDSA 5ARFA 5KJKA 1ZKKA 3SW9A 3KMAA 3CBOA 2R3AA 3OXLA 3OXFA 3DALA 3KMJA 3S7FA 1MT6A 1MVHA 3IHXA 3M5AA 3OOIA 5JJ0A 2F69A 3M53A 4YPUA 4O6FA 3M58A 3OXGA 4QEPA 5KJLA 2IGQA 5F6KC 1H3IA 3BO5A 3RAYA 4NVQA 3QWVA 3M54A 1MVXA 3TG5A 5CCMA 3N71A 5EX0A 5CPRB 4H12A 2RFIA 5T0MA 3S7JA 2BQZA 4Z4PA 3F9XA 4YNPA 4I51A 3M56A 3FPDA 5CCLA 5TEGA 3DB5A 4E47A 3S7DA 3F9ZA 4LDGA 5EX3A 5HI7A 3EP0A 3RU0A 4WUYA 3VUZA 4NJ5A 5AYFA 3OPEA 1XQHA 5F5EA 3MO2A 5T5GA 3SWCA 1PEGA 3K5KA 3M59A 5JINA 3CBPA 3S7BA 5F59A 5TH7A 4QEOA 3MO5A 5KJMA 4YNDA 4O30A 1O9SA 4C1QA 5EG2A 5JIYA 3RIBA 5JHNA 4J7IA 4FMUA 1ML9A 4J7FA 4JLGA 5KJNA 4AU7A 1N6AA 5LSZA 5HQ8A 3M57A 3KMTA 3QWWA 2O8JA 2QPWA 3S8PA 1N3JA 3MEKA 5F6LA 3F9WA 3CBMA 5LSXA 5ARGA 3HNAA 4QENA 5T0KA 3VV0A 4IJ8A 3RJWA 2W5YA 4J83A 4MI0A 4BUPA 5TTFA 1N6CA 4RZ0A 3TG4A 2W5ZA 3QWPA 4YPEA 4YPAA 1MUFA 2JV0A 3M55A 3MO0A 4IJDA 3RQ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F9Y A;  3PDN A;  4J8O A;  2G46 A;  4MI5 A;  4YNM A;  3OS5 A;  4JDS A;  5ARF A;  5KJK A;  1ZKK A;  3SW9 A;  3KMA A;  3CBO A;  2R3A A;  3OXL A;  3OXF A;  3DAL A;  3KMJ A;  3S7F A;  1MT6 A;  1MVH A;  3IHX A;  3M5A A;  3OOI A;  5JJ0 A;  2F69 A;  3M53 A;  4YPU A;  4O6F A;  3M58 A;  3OXG A;  4QEP A;  5KJL A;  2IGQ A;  5F6K C;  1H3I A;  3BO5 A;  3RAY A;  4NVQ A;  3QWV A;  3M54 A;  1MVX A;  3TG5 A;  5CCM A;  3N71 A;  5EX0 A;  5CPR B;  4H12 A;  2RFI A;  5T0M A;  3S7J A;  2BQZ A;  4Z4P A;  3F9X A;  4YNP A;  4I51 A;  3M56 A;  3FPD A;  5CCL A;  5TEG A;  3DB5 A;  4E47 A;  3S7D A;  3F9Z A;  4LDG A;  5EX3 A;  5HI7 A;  3EP0 A;  3RU0 A;  4WUY A;  3VUZ A;  4NJ5 A;  5AYF A;  3OPE A;  1XQH A;  5F5E A;  3MO2 A;  5T5G A;  3SWC A;  1PEG A;  3K5K A;  3M59 A;  5JIN A;  3CBP A;  3S7B A;  5F59 A;  5TH7 A;  4QEO A;  3MO5 A;  5KJM A;  4YND A;  4O30 A;  1O9S A;  4C1Q A;  5EG2 A;  5JIY A;  3RIB A;  5JHN A;  4J7I A;  4FMU A;  1ML9 A;  4J7F A;  4JLG A;  5KJN A;  4AU7 A;  1N6A A;  5LSZ A;  5HQ8 A;  3M57 A;  3KMT A;  3QWW A;  2O8J A;  2QPW A;  3S8P A;  1N3J A;  3MEK A;  5F6L A;  3F9W A;  3CBM A;  5LSX A;  5ARG A;  3HNA A;  4QEN A;  5T0K A;  3VV0 A;  4IJ8 A;  3RJW A;  2W5Y A;  4J83 A;  4MI0 A;  4BUP A;  5TTF A;  1N6C A;  4RZ0 A;  3TG4 A;  2W5Z A;  3QWP A;  4YPE A;  4YPA A;  1MUF A;  2JV0 A;  3M55 A;  3MO0 A;  4IJD A;  3RQ4 A; 
#chains in the Genus database with same CATH topology
 3F9Y A;  3PDN A;  4J8O A;  2G46 A;  4MI5 A;  4YNM A;  3OS5 A;  4JDS A;  5ARF A;  5KJK A;  1ZKK A;  3SW9 A;  3KMA A;  3CBO A;  2R3A A;  3OXL A;  3OXF A;  3DAL A;  3KMJ A;  3S7F A;  1MT6 A;  1MVH A;  3IHX A;  3M5A A;  3OOI A;  5JJ0 A;  2F69 A;  3M53 A;  4YPU A;  4O6F A;  3M58 A;  3OXG A;  4QEP A;  5KJL A;  2IGQ A;  5F6K C;  1H3I A;  3BO5 A;  3RAY A;  4NVQ A;  3QWV A;  3M54 A;  1MVX A;  3TG5 A;  5CCM A;  3N71 A;  5EX0 A;  5CPR B;  4H12 A;  2RFI A;  5T0M A;  3S7J A;  2BQZ A;  4Z4P A;  3F9X A;  4YNP A;  4I51 A;  3M56 A;  3FPD A;  5CCL A;  5TEG A;  3DB5 A;  4E47 A;  3S7D A;  3F9Z A;  4LDG A;  5EX3 A;  5HI7 A;  3EP0 A;  3RU0 A;  4WUY A;  3VUZ A;  4NJ5 A;  5AYF A;  3OPE A;  1XQH A;  5F5E A;  3MO2 A;  5T5G A;  3SWC A;  1PEG A;  3K5K A;  3M59 A;  5JIN A;  3CBP A;  3S7B A;  5F59 A;  5TH7 A;  4QEO A;  3MO5 A;  5KJM A;  4YND A;  4O30 A;  1O9S A;  4C1Q A;  5EG2 A;  5JIY A;  3RIB A;  5JHN A;  4J7I A;  4FMU A;  1ML9 A;  4J7F A;  4JLG A;  5KJN A;  4AU7 A;  1N6A A;  5LSZ A;  5HQ8 A;  3M57 A;  3KMT A;  3QWW A;  2O8J A;  2QPW A;  3S8P A;  1N3J A;  3MEK A;  5F6L A;  3F9W A;  3CBM A;  5LSX A;  5ARG A;  3HNA A;  4QEN A;  5T0K A;  3VV0 A;  4IJ8 A;  3RJW A;  2W5Y A;  4J83 A;  4MI0 A;  4BUP A;  5TTF A;  1N6C A;  4RZ0 A;  3TG4 A;  2W5Z A;  3QWP A;  4YPE A;  4YPA A;  1MUF A;  2JV0 A;  3M55 A;  3MO0 A;  4IJD A;  3RQ4 A; 
#chains in the Genus database with same CATH homology
 3F9Y A;  3PDN A;  4J8O A;  2G46 A;  4MI5 A;  4YNM A;  3OS5 A;  4JDS A;  5ARF A;  5KJK A;  1ZKK A;  3SW9 A;  3KMA A;  3CBO A;  2R3A A;  3OXL A;  3OXF A;  3DAL A;  3KMJ A;  3S7F A;  1MT6 A;  1MVH A;  3IHX A;  3M5A A;  3OOI A;  5JJ0 A;  2F69 A;  3M53 A;  4YPU A;  4O6F A;  3M58 A;  3OXG A;  4QEP A;  5KJL A;  2IGQ A;  5F6K C;  1H3I A;  3BO5 A;  3RAY A;  4NVQ A;  3QWV A;  3M54 A;  1MVX A;  3TG5 A;  5CCM A;  3N71 A;  5EX0 A;  5CPR B;  4H12 A;  2RFI A;  5T0M A;  3S7J A;  2BQZ A;  4Z4P A;  3F9X A;  4YNP A;  4I51 A;  3M56 A;  3FPD A;  5CCL A;  5TEG A;  3DB5 A;  4E47 A;  3S7D A;  3F9Z A;  4LDG A;  5EX3 A;  5HI7 A;  3EP0 A;  3RU0 A;  4WUY A;  3VUZ A;  4NJ5 A;  5AYF A;  3OPE A;  1XQH A;  5F5E A;  3MO2 A;  5T5G A;  3SWC A;  1PEG A;  3K5K A;  3M59 A;  5JIN A;  3CBP A;  3S7B A;  5F59 A;  5TH7 A;  4QEO A;  3MO5 A;  5KJM A;  4YND A;  4O30 A;  1O9S A;  4C1Q A;  5EG2 A;  5JIY A;  3RIB A;  5JHN A;  4J7I A;  4FMU A;  1ML9 A;  4J7F A;  4JLG A;  5KJN A;  4AU7 A;  1N6A A;  5LSZ A;  5HQ8 A;  3M57 A;  3KMT A;  3QWW A;  2O8J A;  2QPW A;  3S8P A;  1N3J A;  3MEK A;  5F6L A;  3F9W A;  3CBM A;  5LSX A;  5ARG A;  3HNA A;  4QEN A;  5T0K A;  3VV0 A;  4IJ8 A;  3RJW A;  2W5Y A;  4J83 A;  4MI0 A;  4BUP A;  5TTF A;  1N6C A;  4RZ0 A;  3TG4 A;  2W5Z A;  3QWP A;  4YPE A;  4YPA A;  1MUF A;  2JV0 A;  3M55 A;  3MO0 A;  4IJD A;  3RQ4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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