1MVHA

Structure of the set domain histone lysine methyltransferase clr4
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
269
structure length
269
Chain Sequence
KLDSYTHLSFYEKRELFRKKLREIEGPEVTLVNEVDDEPCPSLDFQFISQYRLTQGVIPPDPNFQSGCNCSSLGGCDLNNPSRCECLDDLDEPTHFAYDAQGRVRADTGAVIYECNSFCSCSMECPNRVVQRGRTLPLEIFKTKEKGWGVRSLRFAPAGTFITCYLGEVITSAEAAKRDKNYDDDGITYLFDLDMFDDASEYTVDAQNYGDVSRFFNHSCSPNIAIYSAVRNHGFRTIYDLAFFAIKDIQPLEELTFDYAGAKDFSPVQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the SET domain histone lysine methyltransferase Clr4.
pubmed rcsb
molecule tags Transferase
source organism Schizosaccharomyces pombe
molecule keywords Cryptic loci regulator 4
total genus 60
structure length 269
sequence length 269
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1mvhA00
2JV0A 1ZKKA 4YPEA 2F69A 5KJKA 2O8JA 4QEPA 4C1QA 3F9XA 4JDSA 4Z4PA 5EX0A 4YNDA 3TG5A 5EG2A 3PDNA 3RQ4A 4E47A 3MO2A 5ARFA 5TTFA 3M5AA 3F9YA 3S7BA 3DALA 3KMTA 5LSXA 3S7DA 1XQHA 3S8PA 5CCLA 1MVXA 5T0KA 3M56A 5TH7A 4IJDA 1N6CA 4H12A 3IHXA 4RZ0A 5HI7A 3M55A 3N71A 4J83A 5KJNA 4FMUA 4QENA 1ML9A 3S7FA 4J8OA 3RU0A 3M54A 3TG4A 5EX3A 4YNPA 3CBMA 3VUZA 4NJ5A 1PEGA 4NVQA 2RFIA 2W5ZA 1N6AA 3CBOA 3SWCA 1H3IA 3MO5A 3OXLA 3S7JA 4JLGA 3RIBA 3CBPA 4IJ8A 3OPEA 3HNAA 5F5EA 4WUYA 3M57A 5KJMA 3F9ZA 2W5YA 5F6KC 4J7FA 3MEKA 4QEOA 4I51A 4MI5A 5F59A 3M53A 1N3JA 3RJWA 3SW9A 2BQZA 4YPAA 2QPWA 5F6LA 4YPUA 3M58A 3OXFA 5LSZA 1MUFA 5T0MA 3K5KA 5ARGA 3F9WA 3QWWA 5JHNA 3DB5A 4LDGA 3KMAA 1O9SA 3OXGA 5CCMA 3VV0A 3OOIA 4O6FA 5AYFA 3RAYA 5JIYA 5KJLA 2IGQA 1MT6A 3FPDA 2G46A 5JINA 3BO5A 2R3AA 3OS5A 3EP0A 5HQ8A 4J7IA 3QWPA 3KMJA 3M59A 4AU7A 4BUPA 5TEGA 1MVHA 5JJ0A 4O30A 4YNMA 5T5GA 3QWVA 4MI0A 3MO0A 5CPRB
chains in the Genus database with same CATH superfamily
2JV0A 1ZKKA 4YPEA 2F69A 5KJKA 2O8JA 4QEPA 4C1QA 3F9XA 4JDSA 4Z4PA 5EX0A 4YNDA 3TG5A 5EG2A 3PDNA 3RQ4A 4E47A 3MO2A 5ARFA 5TTFA 3M5AA 3F9YA 3S7BA 3DALA 3KMTA 5LSXA 3S7DA 1XQHA 3S8PA 5CCLA 1MVXA 5T0KA 3M56A 5TH7A 4IJDA 1N6CA 4H12A 3IHXA 4RZ0A 5HI7A 3M55A 3N71A 4J83A 5KJNA 4FMUA 4QENA 1ML9A 3S7FA 4J8OA 3RU0A 3M54A 3TG4A 5EX3A 4YNPA 3CBMA 3VUZA 4NJ5A 1PEGA 4NVQA 2RFIA 2W5ZA 1N6AA 3CBOA 3SWCA 1H3IA 3MO5A 3OXLA 3S7JA 4JLGA 3RIBA 3CBPA 4IJ8A 3OPEA 3HNAA 5F5EA 4WUYA 3M57A 5KJMA 3F9ZA 2W5YA 5F6KC 4J7FA 3MEKA 4QEOA 4I51A 4MI5A 5F59A 3M53A 1N3JA 3RJWA 3SW9A 2BQZA 4YPAA 2QPWA 5F6LA 4YPUA 3M58A 3OXFA 5LSZA 1MUFA 5T0MA 3K5KA 5ARGA 3F9WA 3QWWA 5JHNA 3DB5A 4LDGA 3KMAA 1O9SA 3OXGA 5CCMA 3VV0A 3OOIA 4O6FA 5AYFA 3RAYA 5JIYA 5KJLA 2IGQA 1MT6A 3FPDA 2G46A 5JINA 3BO5A 2R3AA 3OS5A 3EP0A 5HQ8A 4J7IA 3QWPA 3KMJA 3M59A 4AU7A 4BUPA 5TEGA 1MVHA 5JJ0A 4O30A 4YNMA 5T5GA 3QWVA 4MI0A 3MO0A 5CPRB
chains in the Genus database with same CATH topology
2JV0A 1ZKKA 4YPEA 2F69A 5KJKA 2O8JA 4QEPA 4C1QA 3F9XA 4JDSA 4Z4PA 5EX0A 4YNDA 3TG5A 5EG2A 3PDNA 3RQ4A 4E47A 3MO2A 5ARFA 5TTFA 3M5AA 3F9YA 3S7BA 3DALA 3KMTA 5LSXA 3S7DA 1XQHA 3S8PA 5CCLA 1MVXA 5T0KA 3M56A 5TH7A 4IJDA 1N6CA 4H12A 3IHXA 4RZ0A 5HI7A 3M55A 3N71A 4J83A 5KJNA 4FMUA 4QENA 1ML9A 3S7FA 4J8OA 3RU0A 3M54A 3TG4A 5EX3A 4YNPA 3CBMA 3VUZA 4NJ5A 1PEGA 4NVQA 2RFIA 2W5ZA 1N6AA 3CBOA 3SWCA 1H3IA 3MO5A 3OXLA 3S7JA 4JLGA 3RIBA 3CBPA 4IJ8A 3OPEA 3HNAA 5F5EA 4WUYA 3M57A 5KJMA 3F9ZA 2W5YA 5F6KC 4J7FA 3MEKA 4QEOA 4I51A 4MI5A 5F59A 3M53A 1N3JA 3RJWA 3SW9A 2BQZA 4YPAA 2QPWA 5F6LA 4YPUA 3M58A 3OXFA 5LSZA 1MUFA 5T0MA 3K5KA 5ARGA 3F9WA 3QWWA 5JHNA 3DB5A 4LDGA 3KMAA 1O9SA 3OXGA 5CCMA 3VV0A 3OOIA 4O6FA 5AYFA 3RAYA 5JIYA 5KJLA 2IGQA 1MT6A 3FPDA 2G46A 5JINA 3BO5A 2R3AA 3OS5A 3EP0A 5HQ8A 4J7IA 3QWPA 3KMJA 3M59A 4AU7A 4BUPA 5TEGA 1MVHA 5JJ0A 4O30A 4YNMA 5T5GA 3QWVA 4MI0A 3MO0A 5CPRB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JV0 A;  1ZKK A;  4YPE A;  2F69 A;  5KJK A;  2O8J A;  4QEP A;  4C1Q A;  3F9X A;  4JDS A;  4Z4P A;  5EX0 A;  4YND A;  3TG5 A;  5EG2 A;  3PDN A;  3RQ4 A;  4E47 A;  3MO2 A;  5ARF A;  5TTF A;  3M5A A;  3F9Y A;  3S7B A;  3DAL A;  3KMT A;  5LSX A;  3S7D A;  1XQH A;  3S8P A;  5CCL A;  1MVX A;  5T0K A;  3M56 A;  5TH7 A;  4IJD A;  1N6C A;  4H12 A;  3IHX A;  4RZ0 A;  5HI7 A;  3M55 A;  3N71 A;  4J83 A;  5KJN A;  4FMU A;  4QEN A;  1ML9 A;  3S7F A;  4J8O A;  3RU0 A;  3M54 A;  3TG4 A;  5EX3 A;  4YNP A;  3CBM A;  3VUZ A;  4NJ5 A;  1PEG A;  4NVQ A;  2RFI A;  2W5Z A;  1N6A A;  3CBO A;  3SWC A;  1H3I A;  3MO5 A;  3OXL A;  3S7J A;  4JLG A;  3RIB A;  3CBP A;  4IJ8 A;  3OPE A;  3HNA A;  5F5E A;  4WUY A;  3M57 A;  5KJM A;  3F9Z A;  2W5Y A;  5F6K C;  4J7F A;  3MEK A;  4QEO A;  4I51 A;  4MI5 A;  5F59 A;  3M53 A;  1N3J A;  3RJW A;  3SW9 A;  2BQZ A;  4YPA A;  2QPW A;  5F6L A;  4YPU A;  3M58 A;  3OXF A;  5LSZ A;  1MUF A;  5T0M A;  3K5K A;  5ARG A;  3F9W A;  3QWW A;  5JHN A;  3DB5 A;  4LDG A;  3KMA A;  1O9S A;  3OXG A;  5CCM A;  3VV0 A;  3OOI A;  4O6F A;  5AYF A;  3RAY A;  5JIY A;  5KJL A;  2IGQ A;  1MT6 A;  3FPD A;  2G46 A;  5JIN A;  3BO5 A;  2R3A A;  3OS5 A;  3EP0 A;  5HQ8 A;  4J7I A;  3QWP A;  3KMJ A;  3M59 A;  4AU7 A;  4BUP A;  5TEG A;  1MVH A;  5JJ0 A;  4O30 A;  4YNM A;  5T5G A;  3QWV A;  4MI0 A;  3MO0 A;  5CPR B; 
#chains in the Genus database with same CATH topology
 2JV0 A;  1ZKK A;  4YPE A;  2F69 A;  5KJK A;  2O8J A;  4QEP A;  4C1Q A;  3F9X A;  4JDS A;  4Z4P A;  5EX0 A;  4YND A;  3TG5 A;  5EG2 A;  3PDN A;  3RQ4 A;  4E47 A;  3MO2 A;  5ARF A;  5TTF A;  3M5A A;  3F9Y A;  3S7B A;  3DAL A;  3KMT A;  5LSX A;  3S7D A;  1XQH A;  3S8P A;  5CCL A;  1MVX A;  5T0K A;  3M56 A;  5TH7 A;  4IJD A;  1N6C A;  4H12 A;  3IHX A;  4RZ0 A;  5HI7 A;  3M55 A;  3N71 A;  4J83 A;  5KJN A;  4FMU A;  4QEN A;  1ML9 A;  3S7F A;  4J8O A;  3RU0 A;  3M54 A;  3TG4 A;  5EX3 A;  4YNP A;  3CBM A;  3VUZ A;  4NJ5 A;  1PEG A;  4NVQ A;  2RFI A;  2W5Z A;  1N6A A;  3CBO A;  3SWC A;  1H3I A;  3MO5 A;  3OXL A;  3S7J A;  4JLG A;  3RIB A;  3CBP A;  4IJ8 A;  3OPE A;  3HNA A;  5F5E A;  4WUY A;  3M57 A;  5KJM A;  3F9Z A;  2W5Y A;  5F6K C;  4J7F A;  3MEK A;  4QEO A;  4I51 A;  4MI5 A;  5F59 A;  3M53 A;  1N3J A;  3RJW A;  3SW9 A;  2BQZ A;  4YPA A;  2QPW A;  5F6L A;  4YPU A;  3M58 A;  3OXF A;  5LSZ A;  1MUF A;  5T0M A;  3K5K A;  5ARG A;  3F9W A;  3QWW A;  5JHN A;  3DB5 A;  4LDG A;  3KMA A;  1O9S A;  3OXG A;  5CCM A;  3VV0 A;  3OOI A;  4O6F A;  5AYF A;  3RAY A;  5JIY A;  5KJL A;  2IGQ A;  1MT6 A;  3FPD A;  2G46 A;  5JIN A;  3BO5 A;  2R3A A;  3OS5 A;  3EP0 A;  5HQ8 A;  4J7I A;  3QWP A;  3KMJ A;  3M59 A;  4AU7 A;  4BUP A;  5TEG A;  1MVH A;  5JJ0 A;  4O30 A;  4YNM A;  5T5G A;  3QWV A;  4MI0 A;  3MO0 A;  5CPR B; 
#chains in the Genus database with same CATH homology
 2JV0 A;  1ZKK A;  4YPE A;  2F69 A;  5KJK A;  2O8J A;  4QEP A;  4C1Q A;  3F9X A;  4JDS A;  4Z4P A;  5EX0 A;  4YND A;  3TG5 A;  5EG2 A;  3PDN A;  3RQ4 A;  4E47 A;  3MO2 A;  5ARF A;  5TTF A;  3M5A A;  3F9Y A;  3S7B A;  3DAL A;  3KMT A;  5LSX A;  3S7D A;  1XQH A;  3S8P A;  5CCL A;  1MVX A;  5T0K A;  3M56 A;  5TH7 A;  4IJD A;  1N6C A;  4H12 A;  3IHX A;  4RZ0 A;  5HI7 A;  3M55 A;  3N71 A;  4J83 A;  5KJN A;  4FMU A;  4QEN A;  1ML9 A;  3S7F A;  4J8O A;  3RU0 A;  3M54 A;  3TG4 A;  5EX3 A;  4YNP A;  3CBM A;  3VUZ A;  4NJ5 A;  1PEG A;  4NVQ A;  2RFI A;  2W5Z A;  1N6A A;  3CBO A;  3SWC A;  1H3I A;  3MO5 A;  3OXL A;  3S7J A;  4JLG A;  3RIB A;  3CBP A;  4IJ8 A;  3OPE A;  3HNA A;  5F5E A;  4WUY A;  3M57 A;  5KJM A;  3F9Z A;  2W5Y A;  5F6K C;  4J7F A;  3MEK A;  4QEO A;  4I51 A;  4MI5 A;  5F59 A;  3M53 A;  1N3J A;  3RJW A;  3SW9 A;  2BQZ A;  4YPA A;  2QPW A;  5F6L A;  4YPU A;  3M58 A;  3OXF A;  5LSZ A;  1MUF A;  5T0M A;  3K5K A;  5ARG A;  3F9W A;  3QWW A;  5JHN A;  3DB5 A;  4LDG A;  3KMA A;  1O9S A;  3OXG A;  5CCM A;  3VV0 A;  3OOI A;  4O6F A;  5AYF A;  3RAY A;  5JIY A;  5KJL A;  2IGQ A;  1MT6 A;  3FPD A;  2G46 A;  5JIN A;  3BO5 A;  2R3A A;  3OS5 A;  3EP0 A;  5HQ8 A;  4J7I A;  3QWP A;  3KMJ A;  3M59 A;  4AU7 A;  4BUP A;  5TEG A;  1MVH A;  5JJ0 A;  4O30 A;  4YNM A;  5T5G A;  3QWV A;  4MI0 A;  3MO0 A;  5CPR B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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