1N6CA

Structure of set7/9
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
285
structure length
283
Chain Sequence
GGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYSPPGKSGPEAPEWYQVELKAFQAT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords SET domain-containing protein 7
total genus 64
structure length 283
sequence length 285
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF02493 MORN MORN repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.110.10 Mainly Beta Single Sheet Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 1n6cA01
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1n6cA02
3SWCA 3S7DA 4YNDA 4IJDA 3RQ4A 4IJ8A 4BUPA 4WUYA 5ARGA 4AU7A 5F59A 3MO2A 3EP0A 3FPDA 3KMJA 1O9SA 5TTFA 3K5KA 2RFIA 3KMAA 5AYFA 2O8JA 5JIYA 4RZ0A 1MUFA 4NJ5A 3F9YA 5CPRB 5EG2A 4I51A 2G46A 3M59A 3S7BA 3TG4A 1PEGA 4JDSA 2W5ZA 4J8OA 4O30A 3QWPA 4FMUA 4O6FA 3OXLA 5T0MA 3OXFA 4QENA 1N6AA 5T0KA 3M56A 3KMTA 4YNMA 5LSZA 4QEOA 5JJ0A 3CBOA 3M58A 3CBMA 4J7FA 5CCLA 3M53A 5HI7A 5ARFA 5EX3A 3RIBA 2QPWA 4JLGA 3OXGA 3MO5A 4Z4PA 4QEPA 4J83A 4H12A 3MO0A 1ZKKA 5KJMA 5TEGA 5LSXA 3QWVA 4E47A 3DB5A 4NVQA 3F9XA 3OS5A 3OOIA 4C1QA 3F9ZA 3RJWA 3M5AA 1MT6A 1N6CA 4YPEA 5CCMA 5F6KC 3BO5A 5F6LA 1H3IA 3PDNA 2JV0A 3MEKA 2BQZA 5F5EA 3IHXA 4MI0A 5KJLA 2F69A 2R3AA 3DALA 4YPAA 4YNPA 3QWWA 4MI5A 2IGQA 3OPEA 5JINA 3SW9A 1N3JA 4YPUA 1ML9A 5KJNA 1MVXA 4LDGA 4J7IA 3S7JA 3S8PA 3M57A 5HQ8A 1XQHA 2W5YA 5EX0A 3RU0A 3M54A 3S7FA 1MVHA 3TG5A 5KJKA 3RAYA 5TH7A 3VUZA 3CBPA 3M55A 5T5GA 5JHNA 3HNAA 3VV0A 3N71A 3F9WA
chains in the Genus database with same CATH superfamily
3SWCA 3S7DA 4YNDA 4IJDA 3RQ4A 4IJ8A 4BUPA 4WUYA 5ARGA 4AU7A 5F59A 3MO2A 3EP0A 3FPDA 3KMJA 1O9SA 5TTFA 3K5KA 2RFIA 3KMAA 5AYFA 2O8JA 5JIYA 4RZ0A 1MUFA 4NJ5A 3F9YA 5CPRB 5EG2A 4I51A 2G46A 3M59A 3S7BA 3TG4A 1PEGA 4JDSA 2W5ZA 4J8OA 4O30A 3QWPA 4FMUA 4O6FA 3OXLA 5T0MA 3OXFA 4QENA 1N6AA 5T0KA 3M56A 3KMTA 4YNMA 5LSZA 4QEOA 5JJ0A 3CBOA 3M58A 3CBMA 4J7FA 5CCLA 3M53A 5HI7A 5ARFA 5EX3A 3RIBA 2QPWA 4JLGA 3OXGA 3MO5A 4Z4PA 4QEPA 4J83A 4H12A 3MO0A 1ZKKA 5KJMA 5TEGA 5LSXA 3QWVA 4E47A 3DB5A 4NVQA 3F9XA 3OS5A 3OOIA 4C1QA 3F9ZA 3RJWA 3M5AA 1MT6A 1N6CA 4YPEA 5CCMA 5F6KC 3BO5A 5F6LA 1H3IA 3PDNA 2JV0A 3MEKA 2BQZA 5F5EA 3IHXA 4MI0A 5KJLA 2F69A 2R3AA 3DALA 4YPAA 4YNPA 3QWWA 4MI5A 2IGQA 3OPEA 5JINA 3SW9A 1N3JA 4YPUA 1ML9A 5KJNA 1MVXA 4LDGA 4J7IA 3S7JA 3S8PA 3M57A 5HQ8A 1XQHA 2W5YA 5EX0A 3RU0A 3M54A 3S7FA 1MVHA 3TG5A 5KJKA 3RAYA 5TH7A 3VUZA 3CBPA 3M55A 5T5GA 5JHNA 3HNAA 3VV0A 3N71A 3F9WA
chains in the Genus database with same CATH topology
3SWCA 3S7DA 4YNDA 4IJDA 3RQ4A 4IJ8A 4BUPA 4WUYA 5ARGA 4AU7A 5F59A 3MO2A 3EP0A 3FPDA 3KMJA 1O9SA 5TTFA 3K5KA 2RFIA 3KMAA 5AYFA 2O8JA 5JIYA 4RZ0A 1MUFA 4NJ5A 3F9YA 5CPRB 5EG2A 4I51A 2G46A 3M59A 3S7BA 3TG4A 1PEGA 4JDSA 2W5ZA 4J8OA 4O30A 3QWPA 4FMUA 4O6FA 3OXLA 5T0MA 3OXFA 4QENA 1N6AA 5T0KA 3M56A 3KMTA 4YNMA 5LSZA 4QEOA 5JJ0A 3CBOA 3M58A 3CBMA 4J7FA 5CCLA 3M53A 5HI7A 5ARFA 5EX3A 3RIBA 2QPWA 4JLGA 3OXGA 3MO5A 4Z4PA 4QEPA 4J83A 4H12A 3MO0A 1ZKKA 5KJMA 5TEGA 5LSXA 3QWVA 4E47A 3DB5A 4NVQA 3F9XA 3OS5A 3OOIA 4C1QA 3F9ZA 3RJWA 3M5AA 1MT6A 1N6CA 4YPEA 5CCMA 5F6KC 3BO5A 5F6LA 1H3IA 3PDNA 2JV0A 3MEKA 2BQZA 5F5EA 3IHXA 4MI0A 5KJLA 2F69A 2R3AA 3DALA 4YPAA 4YNPA 3QWWA 4MI5A 2IGQA 3OPEA 5JINA 3SW9A 1N3JA 4YPUA 1ML9A 5KJNA 1MVXA 4LDGA 4J7IA 3S7JA 3S8PA 3M57A 5HQ8A 1XQHA 2W5YA 5EX0A 3RU0A 3M54A 3S7FA 1MVHA 3TG5A 5KJKA 3RAYA 5TH7A 3VUZA 3CBPA 3M55A 5T5GA 5JHNA 3HNAA 3VV0A 3N71A 3F9WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SWC A;  3S7D A;  4YND A;  4IJD A;  3RQ4 A;  4IJ8 A;  4BUP A;  4WUY A;  5ARG A;  4AU7 A;  5F59 A;  3MO2 A;  3EP0 A;  3FPD A;  3KMJ A;  1O9S A;  5TTF A;  3K5K A;  2RFI A;  3KMA A;  5AYF A;  2O8J A;  5JIY A;  4RZ0 A;  1MUF A;  4NJ5 A;  3F9Y A;  5CPR B;  5EG2 A;  4I51 A;  2G46 A;  3M59 A;  3S7B A;  3TG4 A;  1PEG A;  4JDS A;  2W5Z A;  4J8O A;  4O30 A;  3QWP A;  4FMU A;  4O6F A;  3OXL A;  5T0M A;  3OXF A;  4QEN A;  1N6A A;  5T0K A;  3M56 A;  3KMT A;  4YNM A;  5LSZ A;  4QEO A;  5JJ0 A;  3CBO A;  3M58 A;  3CBM A;  4J7F A;  5CCL A;  3M53 A;  5HI7 A;  5ARF A;  5EX3 A;  3RIB A;  2QPW A;  4JLG A;  3OXG A;  3MO5 A;  4Z4P A;  4QEP A;  4J83 A;  4H12 A;  3MO0 A;  1ZKK A;  5KJM A;  5TEG A;  5LSX A;  3QWV A;  4E47 A;  3DB5 A;  4NVQ A;  3F9X A;  3OS5 A;  3OOI A;  4C1Q A;  3F9Z A;  3RJW A;  3M5A A;  1MT6 A;  1N6C A;  4YPE A;  5CCM A;  5F6K C;  3BO5 A;  5F6L A;  1H3I A;  3PDN A;  2JV0 A;  3MEK A;  2BQZ A;  5F5E A;  3IHX A;  4MI0 A;  5KJL A;  2F69 A;  2R3A A;  3DAL A;  4YPA A;  4YNP A;  3QWW A;  4MI5 A;  2IGQ A;  3OPE A;  5JIN A;  3SW9 A;  1N3J A;  4YPU A;  1ML9 A;  5KJN A;  1MVX A;  4LDG A;  4J7I A;  3S7J A;  3S8P A;  3M57 A;  5HQ8 A;  1XQH A;  2W5Y A;  5EX0 A;  3RU0 A;  3M54 A;  3S7F A;  1MVH A;  3TG5 A;  5KJK A;  3RAY A;  5TH7 A;  3VUZ A;  3CBP A;  3M55 A;  5T5G A;  5JHN A;  3HNA A;  3VV0 A;  3N71 A;  3F9W A; 
#chains in the Genus database with same CATH topology
 3SWC A;  3S7D A;  4YND A;  4IJD A;  3RQ4 A;  4IJ8 A;  4BUP A;  4WUY A;  5ARG A;  4AU7 A;  5F59 A;  3MO2 A;  3EP0 A;  3FPD A;  3KMJ A;  1O9S A;  5TTF A;  3K5K A;  2RFI A;  3KMA A;  5AYF A;  2O8J A;  5JIY A;  4RZ0 A;  1MUF A;  4NJ5 A;  3F9Y A;  5CPR B;  5EG2 A;  4I51 A;  2G46 A;  3M59 A;  3S7B A;  3TG4 A;  1PEG A;  4JDS A;  2W5Z A;  4J8O A;  4O30 A;  3QWP A;  4FMU A;  4O6F A;  3OXL A;  5T0M A;  3OXF A;  4QEN A;  1N6A A;  5T0K A;  3M56 A;  3KMT A;  4YNM A;  5LSZ A;  4QEO A;  5JJ0 A;  3CBO A;  3M58 A;  3CBM A;  4J7F A;  5CCL A;  3M53 A;  5HI7 A;  5ARF A;  5EX3 A;  3RIB A;  2QPW A;  4JLG A;  3OXG A;  3MO5 A;  4Z4P A;  4QEP A;  4J83 A;  4H12 A;  3MO0 A;  1ZKK A;  5KJM A;  5TEG A;  5LSX A;  3QWV A;  4E47 A;  3DB5 A;  4NVQ A;  3F9X A;  3OS5 A;  3OOI A;  4C1Q A;  3F9Z A;  3RJW A;  3M5A A;  1MT6 A;  1N6C A;  4YPE A;  5CCM A;  5F6K C;  3BO5 A;  5F6L A;  1H3I A;  3PDN A;  2JV0 A;  3MEK A;  2BQZ A;  5F5E A;  3IHX A;  4MI0 A;  5KJL A;  2F69 A;  2R3A A;  3DAL A;  4YPA A;  4YNP A;  3QWW A;  4MI5 A;  2IGQ A;  3OPE A;  5JIN A;  3SW9 A;  1N3J A;  4YPU A;  1ML9 A;  5KJN A;  1MVX A;  4LDG A;  4J7I A;  3S7J A;  3S8P A;  3M57 A;  5HQ8 A;  1XQH A;  2W5Y A;  5EX0 A;  3RU0 A;  3M54 A;  3S7F A;  1MVH A;  3TG5 A;  5KJK A;  3RAY A;  5TH7 A;  3VUZ A;  3CBP A;  3M55 A;  5T5G A;  5JHN A;  3HNA A;  3VV0 A;  3N71 A;  3F9W A; 
#chains in the Genus database with same CATH homology
 3SWC A;  3S7D A;  4YND A;  4IJD A;  3RQ4 A;  4IJ8 A;  4BUP A;  4WUY A;  5ARG A;  4AU7 A;  5F59 A;  3MO2 A;  3EP0 A;  3FPD A;  3KMJ A;  1O9S A;  5TTF A;  3K5K A;  2RFI A;  3KMA A;  5AYF A;  2O8J A;  5JIY A;  4RZ0 A;  1MUF A;  4NJ5 A;  3F9Y A;  5CPR B;  5EG2 A;  4I51 A;  2G46 A;  3M59 A;  3S7B A;  3TG4 A;  1PEG A;  4JDS A;  2W5Z A;  4J8O A;  4O30 A;  3QWP A;  4FMU A;  4O6F A;  3OXL A;  5T0M A;  3OXF A;  4QEN A;  1N6A A;  5T0K A;  3M56 A;  3KMT A;  4YNM A;  5LSZ A;  4QEO A;  5JJ0 A;  3CBO A;  3M58 A;  3CBM A;  4J7F A;  5CCL A;  3M53 A;  5HI7 A;  5ARF A;  5EX3 A;  3RIB A;  2QPW A;  4JLG A;  3OXG A;  3MO5 A;  4Z4P A;  4QEP A;  4J83 A;  4H12 A;  3MO0 A;  1ZKK A;  5KJM A;  5TEG A;  5LSX A;  3QWV A;  4E47 A;  3DB5 A;  4NVQ A;  3F9X A;  3OS5 A;  3OOI A;  4C1Q A;  3F9Z A;  3RJW A;  3M5A A;  1MT6 A;  1N6C A;  4YPE A;  5CCM A;  5F6K C;  3BO5 A;  5F6L A;  1H3I A;  3PDN A;  2JV0 A;  3MEK A;  2BQZ A;  5F5E A;  3IHX A;  4MI0 A;  5KJL A;  2F69 A;  2R3A A;  3DAL A;  4YPA A;  4YNP A;  3QWW A;  4MI5 A;  2IGQ A;  3OPE A;  5JIN A;  3SW9 A;  1N3J A;  4YPU A;  1ML9 A;  5KJN A;  1MVX A;  4LDG A;  4J7I A;  3S7J A;  3S8P A;  3M57 A;  5HQ8 A;  1XQH A;  2W5Y A;  5EX0 A;  3RU0 A;  3M54 A;  3S7F A;  1MVH A;  3TG5 A;  5KJK A;  3RAY A;  5TH7 A;  3VUZ A;  3CBP A;  3M55 A;  5T5G A;  5JHN A;  3HNA A;  3VV0 A;  3N71 A;  3F9W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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