2G46A

Structure of vset in complex with mek27 h3 pept. and cofactor product sah
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
119
structure length
119
Chain Sequence
MFNDRVIVKKSPLGGYGVFARKSFEKGELVEECLCIVRHNDDWGTALEDYLFSRKNMSAMALGFGAIFNHSKDPNARHELTAGLKRMRIFTIKPIAIGEEITISYGDDYWLSRPRLTQN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights of the specificity and catalysis of a viral histone H3 lysine 27 methyltransferase.
pubmed doi rcsb
molecule tags Transferase
source organism Paramecium bursaria chlorella virus 1
molecule keywords PBCV-1 histone H3-Lys 27 methyltransferase
total genus 9
structure length 119
sequence length 119
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-02-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 2g46A01
3RQ4A 1MT6A 4J7FA 3DALA 5EX3A 4LDGA 3OOIA 5EX0A 5EG2A 4YNMA 3M56A 2W5ZA 5F6KC 4IJDA 3DB5A 3RAYA 3TG5A 5CCLA 3QWWA 5T0MA 2O8JA 3MEKA 5HI7A 2IGQA 3FPDA 4WUYA 3TG4A 5ARFA 3CBPA 4J8OA 4NVQA 3F9ZA 3F9YA 5TEGA 3CBOA 5CPRB 3HNAA 1MUFA 5JHNA 5KJNA 3M54A 1MVHA 1MVXA 4YPAA 1XQHA 3K5KA 5JIYA 5F6LA 4H12A 5KJKA 3S7BA 4BUPA 2RFIA 1N6CA 4FMUA 3F9WA 5F59A 3CBMA 4RZ0A 1O9SA 4JLGA 5TTFA 1H3IA 2BQZA 4YNPA 1PEGA 5JJ0A 3VV0A 3S8PA 4YPUA 3M55A 3OS5A 3OXFA 1ZKKA 5T0KA 3KMAA 5LSXA 4O6FA 3PDNA 5AYFA 4I51A 4Z4PA 2G46A 2F69A 3S7FA 3M59A 3RIBA 5HQ8A 4NJ5A 2JV0A 4J7IA 3MO0A 4YPEA 4AU7A 3IHXA 3QWVA 3M57A 3S7JA 1N3JA 4YNDA 4QEPA 1ML9A 3N71A 4O30A 3MO2A 3OXLA 5CCMA 3SW9A 3KMJA 2QPWA 5ARGA 4E47A 5TH7A 3VUZA 5F5EA 2W5YA 4C1QA 4QENA 3M53A 3OPEA 4IJ8A 5KJLA 4JDSA 3OXGA 4MI0A 3RJWA 4J83A 2R3AA 3KMTA 5T5GA 5LSZA 1N6AA 3M5AA 5KJMA 4QEOA 3F9XA 3QWPA 3M58A 3MO5A 3BO5A 3SWCA 5JINA 4MI5A 3RU0A 3S7DA 3EP0A
chains in the Genus database with same CATH superfamily
3RQ4A 1MT6A 4J7FA 3DALA 5EX3A 4LDGA 3OOIA 5EX0A 5EG2A 4YNMA 3M56A 2W5ZA 5F6KC 4IJDA 3DB5A 3RAYA 3TG5A 5CCLA 3QWWA 5T0MA 2O8JA 3MEKA 5HI7A 2IGQA 3FPDA 4WUYA 3TG4A 5ARFA 3CBPA 4J8OA 4NVQA 3F9ZA 3F9YA 5TEGA 3CBOA 5CPRB 3HNAA 1MUFA 5JHNA 5KJNA 3M54A 1MVHA 1MVXA 4YPAA 1XQHA 3K5KA 5JIYA 5F6LA 4H12A 5KJKA 3S7BA 4BUPA 2RFIA 1N6CA 4FMUA 3F9WA 5F59A 3CBMA 4RZ0A 1O9SA 4JLGA 5TTFA 1H3IA 2BQZA 4YNPA 1PEGA 5JJ0A 3VV0A 3S8PA 4YPUA 3M55A 3OS5A 3OXFA 1ZKKA 5T0KA 3KMAA 5LSXA 4O6FA 3PDNA 5AYFA 4I51A 4Z4PA 2G46A 2F69A 3S7FA 3M59A 3RIBA 5HQ8A 4NJ5A 2JV0A 4J7IA 3MO0A 4YPEA 4AU7A 3IHXA 3QWVA 3M57A 3S7JA 1N3JA 4YNDA 4QEPA 1ML9A 3N71A 4O30A 3MO2A 3OXLA 5CCMA 3SW9A 3KMJA 2QPWA 5ARGA 4E47A 5TH7A 3VUZA 5F5EA 2W5YA 4C1QA 4QENA 3M53A 3OPEA 4IJ8A 5KJLA 4JDSA 3OXGA 4MI0A 3RJWA 4J83A 2R3AA 3KMTA 5T5GA 5LSZA 1N6AA 3M5AA 5KJMA 4QEOA 3F9XA 3QWPA 3M58A 3MO5A 3BO5A 3SWCA 5JINA 4MI5A 3RU0A 3S7DA 3EP0A
chains in the Genus database with same CATH topology
3RQ4A 1MT6A 4J7FA 3DALA 5EX3A 4LDGA 3OOIA 5EX0A 5EG2A 4YNMA 3M56A 2W5ZA 5F6KC 4IJDA 3DB5A 3RAYA 3TG5A 5CCLA 3QWWA 5T0MA 2O8JA 3MEKA 5HI7A 2IGQA 3FPDA 4WUYA 3TG4A 5ARFA 3CBPA 4J8OA 4NVQA 3F9ZA 3F9YA 5TEGA 3CBOA 5CPRB 3HNAA 1MUFA 5JHNA 5KJNA 3M54A 1MVHA 1MVXA 4YPAA 1XQHA 3K5KA 5JIYA 5F6LA 4H12A 5KJKA 3S7BA 4BUPA 2RFIA 1N6CA 4FMUA 3F9WA 5F59A 3CBMA 4RZ0A 1O9SA 4JLGA 5TTFA 1H3IA 2BQZA 4YNPA 1PEGA 5JJ0A 3VV0A 3S8PA 4YPUA 3M55A 3OS5A 3OXFA 1ZKKA 5T0KA 3KMAA 5LSXA 4O6FA 3PDNA 5AYFA 4I51A 4Z4PA 2G46A 2F69A 3S7FA 3M59A 3RIBA 5HQ8A 4NJ5A 2JV0A 4J7IA 3MO0A 4YPEA 4AU7A 3IHXA 3QWVA 3M57A 3S7JA 1N3JA 4YNDA 4QEPA 1ML9A 3N71A 4O30A 3MO2A 3OXLA 5CCMA 3SW9A 3KMJA 2QPWA 5ARGA 4E47A 5TH7A 3VUZA 5F5EA 2W5YA 4C1QA 4QENA 3M53A 3OPEA 4IJ8A 5KJLA 4JDSA 3OXGA 4MI0A 3RJWA 4J83A 2R3AA 3KMTA 5T5GA 5LSZA 1N6AA 3M5AA 5KJMA 4QEOA 3F9XA 3QWPA 3M58A 3MO5A 3BO5A 3SWCA 5JINA 4MI5A 3RU0A 3S7DA 3EP0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RQ4 A;  1MT6 A;  4J7F A;  3DAL A;  5EX3 A;  4LDG A;  3OOI A;  5EX0 A;  5EG2 A;  4YNM A;  3M56 A;  2W5Z A;  5F6K C;  4IJD A;  3DB5 A;  3RAY A;  3TG5 A;  5CCL A;  3QWW A;  5T0M A;  2O8J A;  3MEK A;  5HI7 A;  2IGQ A;  3FPD A;  4WUY A;  3TG4 A;  5ARF A;  3CBP A;  4J8O A;  4NVQ A;  3F9Z A;  3F9Y A;  5TEG A;  3CBO A;  5CPR B;  3HNA A;  1MUF A;  5JHN A;  5KJN A;  3M54 A;  1MVH A;  1MVX A;  4YPA A;  1XQH A;  3K5K A;  5JIY A;  5F6L A;  4H12 A;  5KJK A;  3S7B A;  4BUP A;  2RFI A;  1N6C A;  4FMU A;  3F9W A;  5F59 A;  3CBM A;  4RZ0 A;  1O9S A;  4JLG A;  5TTF A;  1H3I A;  2BQZ A;  4YNP A;  1PEG A;  5JJ0 A;  3VV0 A;  3S8P A;  4YPU A;  3M55 A;  3OS5 A;  3OXF A;  1ZKK A;  5T0K A;  3KMA A;  5LSX A;  4O6F A;  3PDN A;  5AYF A;  4I51 A;  4Z4P A;  2G46 A;  2F69 A;  3S7F A;  3M59 A;  3RIB A;  5HQ8 A;  4NJ5 A;  2JV0 A;  4J7I A;  3MO0 A;  4YPE A;  4AU7 A;  3IHX A;  3QWV A;  3M57 A;  3S7J A;  1N3J A;  4YND A;  4QEP A;  1ML9 A;  3N71 A;  4O30 A;  3MO2 A;  3OXL A;  5CCM A;  3SW9 A;  3KMJ A;  2QPW A;  5ARG A;  4E47 A;  5TH7 A;  3VUZ A;  5F5E A;  2W5Y A;  4C1Q A;  4QEN A;  3M53 A;  3OPE A;  4IJ8 A;  5KJL A;  4JDS A;  3OXG A;  4MI0 A;  3RJW A;  4J83 A;  2R3A A;  3KMT A;  5T5G A;  5LSZ A;  1N6A A;  3M5A A;  5KJM A;  4QEO A;  3F9X A;  3QWP A;  3M58 A;  3MO5 A;  3BO5 A;  3SWC A;  5JIN A;  4MI5 A;  3RU0 A;  3S7D A;  3EP0 A; 
#chains in the Genus database with same CATH topology
 3RQ4 A;  1MT6 A;  4J7F A;  3DAL A;  5EX3 A;  4LDG A;  3OOI A;  5EX0 A;  5EG2 A;  4YNM A;  3M56 A;  2W5Z A;  5F6K C;  4IJD A;  3DB5 A;  3RAY A;  3TG5 A;  5CCL A;  3QWW A;  5T0M A;  2O8J A;  3MEK A;  5HI7 A;  2IGQ A;  3FPD A;  4WUY A;  3TG4 A;  5ARF A;  3CBP A;  4J8O A;  4NVQ A;  3F9Z A;  3F9Y A;  5TEG A;  3CBO A;  5CPR B;  3HNA A;  1MUF A;  5JHN A;  5KJN A;  3M54 A;  1MVH A;  1MVX A;  4YPA A;  1XQH A;  3K5K A;  5JIY A;  5F6L A;  4H12 A;  5KJK A;  3S7B A;  4BUP A;  2RFI A;  1N6C A;  4FMU A;  3F9W A;  5F59 A;  3CBM A;  4RZ0 A;  1O9S A;  4JLG A;  5TTF A;  1H3I A;  2BQZ A;  4YNP A;  1PEG A;  5JJ0 A;  3VV0 A;  3S8P A;  4YPU A;  3M55 A;  3OS5 A;  3OXF A;  1ZKK A;  5T0K A;  3KMA A;  5LSX A;  4O6F A;  3PDN A;  5AYF A;  4I51 A;  4Z4P A;  2G46 A;  2F69 A;  3S7F A;  3M59 A;  3RIB A;  5HQ8 A;  4NJ5 A;  2JV0 A;  4J7I A;  3MO0 A;  4YPE A;  4AU7 A;  3IHX A;  3QWV A;  3M57 A;  3S7J A;  1N3J A;  4YND A;  4QEP A;  1ML9 A;  3N71 A;  4O30 A;  3MO2 A;  3OXL A;  5CCM A;  3SW9 A;  3KMJ A;  2QPW A;  5ARG A;  4E47 A;  5TH7 A;  3VUZ A;  5F5E A;  2W5Y A;  4C1Q A;  4QEN A;  3M53 A;  3OPE A;  4IJ8 A;  5KJL A;  4JDS A;  3OXG A;  4MI0 A;  3RJW A;  4J83 A;  2R3A A;  3KMT A;  5T5G A;  5LSZ A;  1N6A A;  3M5A A;  5KJM A;  4QEO A;  3F9X A;  3QWP A;  3M58 A;  3MO5 A;  3BO5 A;  3SWC A;  5JIN A;  4MI5 A;  3RU0 A;  3S7D A;  3EP0 A; 
#chains in the Genus database with same CATH homology
 3RQ4 A;  1MT6 A;  4J7F A;  3DAL A;  5EX3 A;  4LDG A;  3OOI A;  5EX0 A;  5EG2 A;  4YNM A;  3M56 A;  2W5Z A;  5F6K C;  4IJD A;  3DB5 A;  3RAY A;  3TG5 A;  5CCL A;  3QWW A;  5T0M A;  2O8J A;  3MEK A;  5HI7 A;  2IGQ A;  3FPD A;  4WUY A;  3TG4 A;  5ARF A;  3CBP A;  4J8O A;  4NVQ A;  3F9Z A;  3F9Y A;  5TEG A;  3CBO A;  5CPR B;  3HNA A;  1MUF A;  5JHN A;  5KJN A;  3M54 A;  1MVH A;  1MVX A;  4YPA A;  1XQH A;  3K5K A;  5JIY A;  5F6L A;  4H12 A;  5KJK A;  3S7B A;  4BUP A;  2RFI A;  1N6C A;  4FMU A;  3F9W A;  5F59 A;  3CBM A;  4RZ0 A;  1O9S A;  4JLG A;  5TTF A;  1H3I A;  2BQZ A;  4YNP A;  1PEG A;  5JJ0 A;  3VV0 A;  3S8P A;  4YPU A;  3M55 A;  3OS5 A;  3OXF A;  1ZKK A;  5T0K A;  3KMA A;  5LSX A;  4O6F A;  3PDN A;  5AYF A;  4I51 A;  4Z4P A;  2G46 A;  2F69 A;  3S7F A;  3M59 A;  3RIB A;  5HQ8 A;  4NJ5 A;  2JV0 A;  4J7I A;  3MO0 A;  4YPE A;  4AU7 A;  3IHX A;  3QWV A;  3M57 A;  3S7J A;  1N3J A;  4YND A;  4QEP A;  1ML9 A;  3N71 A;  4O30 A;  3MO2 A;  3OXL A;  5CCM A;  3SW9 A;  3KMJ A;  2QPW A;  5ARG A;  4E47 A;  5TH7 A;  3VUZ A;  5F5E A;  2W5Y A;  4C1Q A;  4QEN A;  3M53 A;  3OPE A;  4IJ8 A;  5KJL A;  4JDS A;  3OXG A;  4MI0 A;  3RJW A;  4J83 A;  2R3A A;  3KMT A;  5T5G A;  5LSZ A;  1N6A A;  3M5A A;  5KJM A;  4QEO A;  3F9X A;  3QWP A;  3M58 A;  3MO5 A;  3BO5 A;  3SWC A;  5JIN A;  4MI5 A;  3RU0 A;  3S7D A;  3EP0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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