2IGQA

Human euchromatic histone methyltransferase 1
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
260
structure length
251
Chain Sequence
ERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDCSSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELISDSEADVREEDSYLFDLVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYGERFWDIKGSCRCGSPKCRHS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural biology of human H3K9 methyltransferases
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords euchromatic histone methyltransferase 1
total genus 62
structure length 251
sequence length 260
chains with identical sequence B
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2006-09-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 2igqA00
3CBPA 3S8PA 3DALA 4YPEA 2IGQA 3DB5A 3K5KA 4YNPA 3M56A 4J7FA 1MUFA 3SW9A 4YNDA 3M5AA 5ARGA 5EX3A 4WUYA 5F59A 5KJMA 3QWWA 3OXFA 3RQ4A 3M59A 5HQ8A 3OXGA 5EX0A 3F9WA 5KJKA 3MO0A 4LDGA 4NVQA 5JJ0A 5EG2A 4MI5A 5LSZA 1ML9A 4QEOA 3N71A 5TTFA 1N6CA 4YNMA 4YPUA 5JINA 2QPWA 4J7IA 3OOIA 1XQHA 4O30A 5ARFA 3RU0A 4QEPA 3M57A 3OXLA 3FPDA 3M53A 5LSXA 2BQZA 3TG5A 3MEKA 5CPRB 3OS5A 2R3AA 3QWVA 4JLGA 5T0KA 5TH7A 3BO5A 2G46A 1MVHA 3VV0A 3S7BA 3F9XA 5KJLA 5KJNA 4IJ8A 5T5GA 1MVXA 3KMJA 1N3JA 4H12A 4FMUA 1ZKKA 2O8JA 3M54A 1PEGA 3M58A 4I51A 2RFIA 4RZ0A 5TEGA 2W5YA 3CBMA 3OPEA 3S7DA 3QWPA 4J83A 3F9ZA 4Z4PA 4QENA 3TG4A 4IJDA 3RIBA 5AYFA 4YPAA 5F5EA 1O9SA 2JV0A 5F6LA 3KMAA 3CBOA 3HNAA 5CCLA 3MO2A 3IHXA 4C1QA 3SWCA 5CCMA 1N6AA 3RJWA 5JIYA 3EP0A 4NJ5A 5F6KC 3S7FA 4J8OA 3M55A 3KMTA 4MI0A 4JDSA 1H3IA 3RAYA 4AU7A 1MT6A 5T0MA 2F69A 4E47A 3MO5A 2W5ZA 3F9YA 4O6FA 3PDNA 5HI7A 3S7JA 5JHNA 4BUPA 3VUZA
chains in the Genus database with same CATH superfamily
3CBPA 3S8PA 3DALA 4YPEA 2IGQA 3DB5A 3K5KA 4YNPA 3M56A 4J7FA 1MUFA 3SW9A 4YNDA 3M5AA 5ARGA 5EX3A 4WUYA 5F59A 5KJMA 3QWWA 3OXFA 3RQ4A 3M59A 5HQ8A 3OXGA 5EX0A 3F9WA 5KJKA 3MO0A 4LDGA 4NVQA 5JJ0A 5EG2A 4MI5A 5LSZA 1ML9A 4QEOA 3N71A 5TTFA 1N6CA 4YNMA 4YPUA 5JINA 2QPWA 4J7IA 3OOIA 1XQHA 4O30A 5ARFA 3RU0A 4QEPA 3M57A 3OXLA 3FPDA 3M53A 5LSXA 2BQZA 3TG5A 3MEKA 5CPRB 3OS5A 2R3AA 3QWVA 4JLGA 5T0KA 5TH7A 3BO5A 2G46A 1MVHA 3VV0A 3S7BA 3F9XA 5KJLA 5KJNA 4IJ8A 5T5GA 1MVXA 3KMJA 1N3JA 4H12A 4FMUA 1ZKKA 2O8JA 3M54A 1PEGA 3M58A 4I51A 2RFIA 4RZ0A 5TEGA 2W5YA 3CBMA 3OPEA 3S7DA 3QWPA 4J83A 3F9ZA 4Z4PA 4QENA 3TG4A 4IJDA 3RIBA 5AYFA 4YPAA 5F5EA 1O9SA 2JV0A 5F6LA 3KMAA 3CBOA 3HNAA 5CCLA 3MO2A 3IHXA 4C1QA 3SWCA 5CCMA 1N6AA 3RJWA 5JIYA 3EP0A 4NJ5A 5F6KC 3S7FA 4J8OA 3M55A 3KMTA 4MI0A 4JDSA 1H3IA 3RAYA 4AU7A 1MT6A 5T0MA 2F69A 4E47A 3MO5A 2W5ZA 3F9YA 4O6FA 3PDNA 5HI7A 3S7JA 5JHNA 4BUPA 3VUZA
chains in the Genus database with same CATH topology
3CBPA 3S8PA 3DALA 4YPEA 2IGQA 3DB5A 3K5KA 4YNPA 3M56A 4J7FA 1MUFA 3SW9A 4YNDA 3M5AA 5ARGA 5EX3A 4WUYA 5F59A 5KJMA 3QWWA 3OXFA 3RQ4A 3M59A 5HQ8A 3OXGA 5EX0A 3F9WA 5KJKA 3MO0A 4LDGA 4NVQA 5JJ0A 5EG2A 4MI5A 5LSZA 1ML9A 4QEOA 3N71A 5TTFA 1N6CA 4YNMA 4YPUA 5JINA 2QPWA 4J7IA 3OOIA 1XQHA 4O30A 5ARFA 3RU0A 4QEPA 3M57A 3OXLA 3FPDA 3M53A 5LSXA 2BQZA 3TG5A 3MEKA 5CPRB 3OS5A 2R3AA 3QWVA 4JLGA 5T0KA 5TH7A 3BO5A 2G46A 1MVHA 3VV0A 3S7BA 3F9XA 5KJLA 5KJNA 4IJ8A 5T5GA 1MVXA 3KMJA 1N3JA 4H12A 4FMUA 1ZKKA 2O8JA 3M54A 1PEGA 3M58A 4I51A 2RFIA 4RZ0A 5TEGA 2W5YA 3CBMA 3OPEA 3S7DA 3QWPA 4J83A 3F9ZA 4Z4PA 4QENA 3TG4A 4IJDA 3RIBA 5AYFA 4YPAA 5F5EA 1O9SA 2JV0A 5F6LA 3KMAA 3CBOA 3HNAA 5CCLA 3MO2A 3IHXA 4C1QA 3SWCA 5CCMA 1N6AA 3RJWA 5JIYA 3EP0A 4NJ5A 5F6KC 3S7FA 4J8OA 3M55A 3KMTA 4MI0A 4JDSA 1H3IA 3RAYA 4AU7A 1MT6A 5T0MA 2F69A 4E47A 3MO5A 2W5ZA 3F9YA 4O6FA 3PDNA 5HI7A 3S7JA 5JHNA 4BUPA 3VUZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CBP A;  3S8P A;  3DAL A;  4YPE A;  2IGQ A;  3DB5 A;  3K5K A;  4YNP A;  3M56 A;  4J7F A;  1MUF A;  3SW9 A;  4YND A;  3M5A A;  5ARG A;  5EX3 A;  4WUY A;  5F59 A;  5KJM A;  3QWW A;  3OXF A;  3RQ4 A;  3M59 A;  5HQ8 A;  3OXG A;  5EX0 A;  3F9W A;  5KJK A;  3MO0 A;  4LDG A;  4NVQ A;  5JJ0 A;  5EG2 A;  4MI5 A;  5LSZ A;  1ML9 A;  4QEO A;  3N71 A;  5TTF A;  1N6C A;  4YNM A;  4YPU A;  5JIN A;  2QPW A;  4J7I A;  3OOI A;  1XQH A;  4O30 A;  5ARF A;  3RU0 A;  4QEP A;  3M57 A;  3OXL A;  3FPD A;  3M53 A;  5LSX A;  2BQZ A;  3TG5 A;  3MEK A;  5CPR B;  3OS5 A;  2R3A A;  3QWV A;  4JLG A;  5T0K A;  5TH7 A;  3BO5 A;  2G46 A;  1MVH A;  3VV0 A;  3S7B A;  3F9X A;  5KJL A;  5KJN A;  4IJ8 A;  5T5G A;  1MVX A;  3KMJ A;  1N3J A;  4H12 A;  4FMU A;  1ZKK A;  2O8J A;  3M54 A;  1PEG A;  3M58 A;  4I51 A;  2RFI A;  4RZ0 A;  5TEG A;  2W5Y A;  3CBM A;  3OPE A;  3S7D A;  3QWP A;  4J83 A;  3F9Z A;  4Z4P A;  4QEN A;  3TG4 A;  4IJD A;  3RIB A;  5AYF A;  4YPA A;  5F5E A;  1O9S A;  2JV0 A;  5F6L A;  3KMA A;  3CBO A;  3HNA A;  5CCL A;  3MO2 A;  3IHX A;  4C1Q A;  3SWC A;  5CCM A;  1N6A A;  3RJW A;  5JIY A;  3EP0 A;  4NJ5 A;  5F6K C;  3S7F A;  4J8O A;  3M55 A;  3KMT A;  4MI0 A;  4JDS A;  1H3I A;  3RAY A;  4AU7 A;  1MT6 A;  5T0M A;  2F69 A;  4E47 A;  3MO5 A;  2W5Z A;  3F9Y A;  4O6F A;  3PDN A;  5HI7 A;  3S7J A;  5JHN A;  4BUP A;  3VUZ A; 
#chains in the Genus database with same CATH topology
 3CBP A;  3S8P A;  3DAL A;  4YPE A;  2IGQ A;  3DB5 A;  3K5K A;  4YNP A;  3M56 A;  4J7F A;  1MUF A;  3SW9 A;  4YND A;  3M5A A;  5ARG A;  5EX3 A;  4WUY A;  5F59 A;  5KJM A;  3QWW A;  3OXF A;  3RQ4 A;  3M59 A;  5HQ8 A;  3OXG A;  5EX0 A;  3F9W A;  5KJK A;  3MO0 A;  4LDG A;  4NVQ A;  5JJ0 A;  5EG2 A;  4MI5 A;  5LSZ A;  1ML9 A;  4QEO A;  3N71 A;  5TTF A;  1N6C A;  4YNM A;  4YPU A;  5JIN A;  2QPW A;  4J7I A;  3OOI A;  1XQH A;  4O30 A;  5ARF A;  3RU0 A;  4QEP A;  3M57 A;  3OXL A;  3FPD A;  3M53 A;  5LSX A;  2BQZ A;  3TG5 A;  3MEK A;  5CPR B;  3OS5 A;  2R3A A;  3QWV A;  4JLG A;  5T0K A;  5TH7 A;  3BO5 A;  2G46 A;  1MVH A;  3VV0 A;  3S7B A;  3F9X A;  5KJL A;  5KJN A;  4IJ8 A;  5T5G A;  1MVX A;  3KMJ A;  1N3J A;  4H12 A;  4FMU A;  1ZKK A;  2O8J A;  3M54 A;  1PEG A;  3M58 A;  4I51 A;  2RFI A;  4RZ0 A;  5TEG A;  2W5Y A;  3CBM A;  3OPE A;  3S7D A;  3QWP A;  4J83 A;  3F9Z A;  4Z4P A;  4QEN A;  3TG4 A;  4IJD A;  3RIB A;  5AYF A;  4YPA A;  5F5E A;  1O9S A;  2JV0 A;  5F6L A;  3KMA A;  3CBO A;  3HNA A;  5CCL A;  3MO2 A;  3IHX A;  4C1Q A;  3SWC A;  5CCM A;  1N6A A;  3RJW A;  5JIY A;  3EP0 A;  4NJ5 A;  5F6K C;  3S7F A;  4J8O A;  3M55 A;  3KMT A;  4MI0 A;  4JDS A;  1H3I A;  3RAY A;  4AU7 A;  1MT6 A;  5T0M A;  2F69 A;  4E47 A;  3MO5 A;  2W5Z A;  3F9Y A;  4O6F A;  3PDN A;  5HI7 A;  3S7J A;  5JHN A;  4BUP A;  3VUZ A; 
#chains in the Genus database with same CATH homology
 3CBP A;  3S8P A;  3DAL A;  4YPE A;  2IGQ A;  3DB5 A;  3K5K A;  4YNP A;  3M56 A;  4J7F A;  1MUF A;  3SW9 A;  4YND A;  3M5A A;  5ARG A;  5EX3 A;  4WUY A;  5F59 A;  5KJM A;  3QWW A;  3OXF A;  3RQ4 A;  3M59 A;  5HQ8 A;  3OXG A;  5EX0 A;  3F9W A;  5KJK A;  3MO0 A;  4LDG A;  4NVQ A;  5JJ0 A;  5EG2 A;  4MI5 A;  5LSZ A;  1ML9 A;  4QEO A;  3N71 A;  5TTF A;  1N6C A;  4YNM A;  4YPU A;  5JIN A;  2QPW A;  4J7I A;  3OOI A;  1XQH A;  4O30 A;  5ARF A;  3RU0 A;  4QEP A;  3M57 A;  3OXL A;  3FPD A;  3M53 A;  5LSX A;  2BQZ A;  3TG5 A;  3MEK A;  5CPR B;  3OS5 A;  2R3A A;  3QWV A;  4JLG A;  5T0K A;  5TH7 A;  3BO5 A;  2G46 A;  1MVH A;  3VV0 A;  3S7B A;  3F9X A;  5KJL A;  5KJN A;  4IJ8 A;  5T5G A;  1MVX A;  3KMJ A;  1N3J A;  4H12 A;  4FMU A;  1ZKK A;  2O8J A;  3M54 A;  1PEG A;  3M58 A;  4I51 A;  2RFI A;  4RZ0 A;  5TEG A;  2W5Y A;  3CBM A;  3OPE A;  3S7D A;  3QWP A;  4J83 A;  3F9Z A;  4Z4P A;  4QEN A;  3TG4 A;  4IJD A;  3RIB A;  5AYF A;  4YPA A;  5F5E A;  1O9S A;  2JV0 A;  5F6L A;  3KMA A;  3CBO A;  3HNA A;  5CCL A;  3MO2 A;  3IHX A;  4C1Q A;  3SWC A;  5CCM A;  1N6A A;  3RJW A;  5JIY A;  3EP0 A;  4NJ5 A;  5F6K C;  3S7F A;  4J8O A;  3M55 A;  3KMT A;  4MI0 A;  4JDS A;  1H3I A;  3RAY A;  4AU7 A;  1MT6 A;  5T0M A;  2F69 A;  4E47 A;  3MO5 A;  2W5Z A;  3F9Y A;  4O6F A;  3PDN A;  5HI7 A;  3S7J A;  5JHN A;  4BUP A;  3VUZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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