2QPWA

Methyltransferase domain of human pr domain-containing protein 2
Total Genus 31
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
147
structure length
147
Chain Sequence
NQNTTEPVAATETLAEVPEHVLRGLPEEVRLFPSAVDKTRIGVWATKPILKGKKFGPFVGDKKKRSQVKNNVYMWEVYYPNLGWMCIDATDPEKGNWLRYVNWACSGEEQNLFPLEINRAIYYKTLKPIAPGEELLVWYNGEDNPEI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural biology of human H3K9 methyltransferases
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords PR domain zinc finger protein 2
total genus 31
structure length 147
sequence length 147
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2007-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 2qpwA01
5CPRB 3M58A 2O8JA 5F6KC 3N71A 5KJNA 5LSZA 5F59A 3M5AA 1PEGA 4JLGA 5EX3A 5CCMA 3S7JA 2F69A 3M55A 3QWPA 4IJ8A 5F6LA 3SW9A 1XQHA 4YPAA 3F9YA 3TG4A 3F9XA 3QWWA 1H3IA 4YNPA 3MO2A 3M57A 4YPEA 4J8OA 1ZKKA 4YPUA 3S7DA 4NVQA 5T0MA 2BQZA 4LDGA 3S8PA 4BUPA 4FMUA 3M59A 4YNMA 3F9ZA 4WUYA 4MI0A 2R3AA 3M56A 4YNDA 5TH7A 3RQ4A 3PDNA 2G46A 1N6CA 5JINA 4AU7A 3BO5A 4O30A 3CBMA 4NJ5A 3VUZA 5CCLA 2JV0A 3EP0A 2W5ZA 3SWCA 4O6FA 5JIYA 4MI5A 3FPDA 3RJWA 4E47A 3OOIA 1N3JA 3OPEA 5TTFA 5ARGA 3K5KA 4Z4PA 3HNAA 3QWVA 5HI7A 4QENA 2IGQA 1MT6A 3CBOA 3F9WA 5ARFA 4JDSA 4RZ0A 5EG2A 5EX0A 5AYFA 4J7IA 4I51A 5KJLA 3S7FA 1MVXA 1MVHA 4J83A 3CBPA 1ML9A 3MO0A 3KMJA 4H12A 3KMAA 4J7FA 3RU0A 5T0KA 4QEOA 5LSXA 3TG5A 3DB5A 3OS5A 3M54A 3OXLA 3S7BA 2RFIA 5F5EA 1N6AA 5TEGA 3VV0A 5HQ8A 3MEKA 3DALA 3RAYA 1MUFA 4QEPA 5T5GA 2W5YA 3IHXA 3M53A 5JJ0A 5KJKA 3RIBA 5KJMA 1O9SA 3KMTA 4C1QA 5JHNA 2QPWA 3OXGA 3OXFA 3MO5A 4IJDA
chains in the Genus database with same CATH superfamily
5CPRB 3M58A 2O8JA 5F6KC 3N71A 5KJNA 5LSZA 5F59A 3M5AA 1PEGA 4JLGA 5EX3A 5CCMA 3S7JA 2F69A 3M55A 3QWPA 4IJ8A 5F6LA 3SW9A 1XQHA 4YPAA 3F9YA 3TG4A 3F9XA 3QWWA 1H3IA 4YNPA 3MO2A 3M57A 4YPEA 4J8OA 1ZKKA 4YPUA 3S7DA 4NVQA 5T0MA 2BQZA 4LDGA 3S8PA 4BUPA 4FMUA 3M59A 4YNMA 3F9ZA 4WUYA 4MI0A 2R3AA 3M56A 4YNDA 5TH7A 3RQ4A 3PDNA 2G46A 1N6CA 5JINA 4AU7A 3BO5A 4O30A 3CBMA 4NJ5A 3VUZA 5CCLA 2JV0A 3EP0A 2W5ZA 3SWCA 4O6FA 5JIYA 4MI5A 3FPDA 3RJWA 4E47A 3OOIA 1N3JA 3OPEA 5TTFA 5ARGA 3K5KA 4Z4PA 3HNAA 3QWVA 5HI7A 4QENA 2IGQA 1MT6A 3CBOA 3F9WA 5ARFA 4JDSA 4RZ0A 5EG2A 5EX0A 5AYFA 4J7IA 4I51A 5KJLA 3S7FA 1MVXA 1MVHA 4J83A 3CBPA 1ML9A 3MO0A 3KMJA 4H12A 3KMAA 4J7FA 3RU0A 5T0KA 4QEOA 5LSXA 3TG5A 3DB5A 3OS5A 3M54A 3OXLA 3S7BA 2RFIA 5F5EA 1N6AA 5TEGA 3VV0A 5HQ8A 3MEKA 3DALA 3RAYA 1MUFA 4QEPA 5T5GA 2W5YA 3IHXA 3M53A 5JJ0A 5KJKA 3RIBA 5KJMA 1O9SA 3KMTA 4C1QA 5JHNA 2QPWA 3OXGA 3OXFA 3MO5A 4IJDA
chains in the Genus database with same CATH topology
5CPRB 3M58A 2O8JA 5F6KC 3N71A 5KJNA 5LSZA 5F59A 3M5AA 1PEGA 4JLGA 5EX3A 5CCMA 3S7JA 2F69A 3M55A 3QWPA 4IJ8A 5F6LA 3SW9A 1XQHA 4YPAA 3F9YA 3TG4A 3F9XA 3QWWA 1H3IA 4YNPA 3MO2A 3M57A 4YPEA 4J8OA 1ZKKA 4YPUA 3S7DA 4NVQA 5T0MA 2BQZA 4LDGA 3S8PA 4BUPA 4FMUA 3M59A 4YNMA 3F9ZA 4WUYA 4MI0A 2R3AA 3M56A 4YNDA 5TH7A 3RQ4A 3PDNA 2G46A 1N6CA 5JINA 4AU7A 3BO5A 4O30A 3CBMA 4NJ5A 3VUZA 5CCLA 2JV0A 3EP0A 2W5ZA 3SWCA 4O6FA 5JIYA 4MI5A 3FPDA 3RJWA 4E47A 3OOIA 1N3JA 3OPEA 5TTFA 5ARGA 3K5KA 4Z4PA 3HNAA 3QWVA 5HI7A 4QENA 2IGQA 1MT6A 3CBOA 3F9WA 5ARFA 4JDSA 4RZ0A 5EG2A 5EX0A 5AYFA 4J7IA 4I51A 5KJLA 3S7FA 1MVXA 1MVHA 4J83A 3CBPA 1ML9A 3MO0A 3KMJA 4H12A 3KMAA 4J7FA 3RU0A 5T0KA 4QEOA 5LSXA 3TG5A 3DB5A 3OS5A 3M54A 3OXLA 3S7BA 2RFIA 5F5EA 1N6AA 5TEGA 3VV0A 5HQ8A 3MEKA 3DALA 3RAYA 1MUFA 4QEPA 5T5GA 2W5YA 3IHXA 3M53A 5JJ0A 5KJKA 3RIBA 5KJMA 1O9SA 3KMTA 4C1QA 5JHNA 2QPWA 3OXGA 3OXFA 3MO5A 4IJDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CPR B;  3M58 A;  2O8J A;  5F6K C;  3N71 A;  5KJN A;  5LSZ A;  5F59 A;  3M5A A;  1PEG A;  4JLG A;  5EX3 A;  5CCM A;  3S7J A;  2F69 A;  3M55 A;  3QWP A;  4IJ8 A;  5F6L A;  3SW9 A;  1XQH A;  4YPA A;  3F9Y A;  3TG4 A;  3F9X A;  3QWW A;  1H3I A;  4YNP A;  3MO2 A;  3M57 A;  4YPE A;  4J8O A;  1ZKK A;  4YPU A;  3S7D A;  4NVQ A;  5T0M A;  2BQZ A;  4LDG A;  3S8P A;  4BUP A;  4FMU A;  3M59 A;  4YNM A;  3F9Z A;  4WUY A;  4MI0 A;  2R3A A;  3M56 A;  4YND A;  5TH7 A;  3RQ4 A;  3PDN A;  2G46 A;  1N6C A;  5JIN A;  4AU7 A;  3BO5 A;  4O30 A;  3CBM A;  4NJ5 A;  3VUZ A;  5CCL A;  2JV0 A;  3EP0 A;  2W5Z A;  3SWC A;  4O6F A;  5JIY A;  4MI5 A;  3FPD A;  3RJW A;  4E47 A;  3OOI A;  1N3J A;  3OPE A;  5TTF A;  5ARG A;  3K5K A;  4Z4P A;  3HNA A;  3QWV A;  5HI7 A;  4QEN A;  2IGQ A;  1MT6 A;  3CBO A;  3F9W A;  5ARF A;  4JDS A;  4RZ0 A;  5EG2 A;  5EX0 A;  5AYF A;  4J7I A;  4I51 A;  5KJL A;  3S7F A;  1MVX A;  1MVH A;  4J83 A;  3CBP A;  1ML9 A;  3MO0 A;  3KMJ A;  4H12 A;  3KMA A;  4J7F A;  3RU0 A;  5T0K A;  4QEO A;  5LSX A;  3TG5 A;  3DB5 A;  3OS5 A;  3M54 A;  3OXL A;  3S7B A;  2RFI A;  5F5E A;  1N6A A;  5TEG A;  3VV0 A;  5HQ8 A;  3MEK A;  3DAL A;  3RAY A;  1MUF A;  4QEP A;  5T5G A;  2W5Y A;  3IHX A;  3M53 A;  5JJ0 A;  5KJK A;  3RIB A;  5KJM A;  1O9S A;  3KMT A;  4C1Q A;  5JHN A;  2QPW A;  3OXG A;  3OXF A;  3MO5 A;  4IJD A; 
#chains in the Genus database with same CATH topology
 5CPR B;  3M58 A;  2O8J A;  5F6K C;  3N71 A;  5KJN A;  5LSZ A;  5F59 A;  3M5A A;  1PEG A;  4JLG A;  5EX3 A;  5CCM A;  3S7J A;  2F69 A;  3M55 A;  3QWP A;  4IJ8 A;  5F6L A;  3SW9 A;  1XQH A;  4YPA A;  3F9Y A;  3TG4 A;  3F9X A;  3QWW A;  1H3I A;  4YNP A;  3MO2 A;  3M57 A;  4YPE A;  4J8O A;  1ZKK A;  4YPU A;  3S7D A;  4NVQ A;  5T0M A;  2BQZ A;  4LDG A;  3S8P A;  4BUP A;  4FMU A;  3M59 A;  4YNM A;  3F9Z A;  4WUY A;  4MI0 A;  2R3A A;  3M56 A;  4YND A;  5TH7 A;  3RQ4 A;  3PDN A;  2G46 A;  1N6C A;  5JIN A;  4AU7 A;  3BO5 A;  4O30 A;  3CBM A;  4NJ5 A;  3VUZ A;  5CCL A;  2JV0 A;  3EP0 A;  2W5Z A;  3SWC A;  4O6F A;  5JIY A;  4MI5 A;  3FPD A;  3RJW A;  4E47 A;  3OOI A;  1N3J A;  3OPE A;  5TTF A;  5ARG A;  3K5K A;  4Z4P A;  3HNA A;  3QWV A;  5HI7 A;  4QEN A;  2IGQ A;  1MT6 A;  3CBO A;  3F9W A;  5ARF A;  4JDS A;  4RZ0 A;  5EG2 A;  5EX0 A;  5AYF A;  4J7I A;  4I51 A;  5KJL A;  3S7F A;  1MVX A;  1MVH A;  4J83 A;  3CBP A;  1ML9 A;  3MO0 A;  3KMJ A;  4H12 A;  3KMA A;  4J7F A;  3RU0 A;  5T0K A;  4QEO A;  5LSX A;  3TG5 A;  3DB5 A;  3OS5 A;  3M54 A;  3OXL A;  3S7B A;  2RFI A;  5F5E A;  1N6A A;  5TEG A;  3VV0 A;  5HQ8 A;  3MEK A;  3DAL A;  3RAY A;  1MUF A;  4QEP A;  5T5G A;  2W5Y A;  3IHX A;  3M53 A;  5JJ0 A;  5KJK A;  3RIB A;  5KJM A;  1O9S A;  3KMT A;  4C1Q A;  5JHN A;  2QPW A;  3OXG A;  3OXF A;  3MO5 A;  4IJD A; 
#chains in the Genus database with same CATH homology
 5CPR B;  3M58 A;  2O8J A;  5F6K C;  3N71 A;  5KJN A;  5LSZ A;  5F59 A;  3M5A A;  1PEG A;  4JLG A;  5EX3 A;  5CCM A;  3S7J A;  2F69 A;  3M55 A;  3QWP A;  4IJ8 A;  5F6L A;  3SW9 A;  1XQH A;  4YPA A;  3F9Y A;  3TG4 A;  3F9X A;  3QWW A;  1H3I A;  4YNP A;  3MO2 A;  3M57 A;  4YPE A;  4J8O A;  1ZKK A;  4YPU A;  3S7D A;  4NVQ A;  5T0M A;  2BQZ A;  4LDG A;  3S8P A;  4BUP A;  4FMU A;  3M59 A;  4YNM A;  3F9Z A;  4WUY A;  4MI0 A;  2R3A A;  3M56 A;  4YND A;  5TH7 A;  3RQ4 A;  3PDN A;  2G46 A;  1N6C A;  5JIN A;  4AU7 A;  3BO5 A;  4O30 A;  3CBM A;  4NJ5 A;  3VUZ A;  5CCL A;  2JV0 A;  3EP0 A;  2W5Z A;  3SWC A;  4O6F A;  5JIY A;  4MI5 A;  3FPD A;  3RJW A;  4E47 A;  3OOI A;  1N3J A;  3OPE A;  5TTF A;  5ARG A;  3K5K A;  4Z4P A;  3HNA A;  3QWV A;  5HI7 A;  4QEN A;  2IGQ A;  1MT6 A;  3CBO A;  3F9W A;  5ARF A;  4JDS A;  4RZ0 A;  5EG2 A;  5EX0 A;  5AYF A;  4J7I A;  4I51 A;  5KJL A;  3S7F A;  1MVX A;  1MVH A;  4J83 A;  3CBP A;  1ML9 A;  3MO0 A;  3KMJ A;  4H12 A;  3KMA A;  4J7F A;  3RU0 A;  5T0K A;  4QEO A;  5LSX A;  3TG5 A;  3DB5 A;  3OS5 A;  3M54 A;  3OXL A;  3S7B A;  2RFI A;  5F5E A;  1N6A A;  5TEG A;  3VV0 A;  5HQ8 A;  3MEK A;  3DAL A;  3RAY A;  1MUF A;  4QEP A;  5T5G A;  2W5Y A;  3IHX A;  3M53 A;  5JJ0 A;  5KJK A;  3RIB A;  5KJM A;  1O9S A;  3KMT A;  4C1Q A;  5JHN A;  2QPW A;  3OXG A;  3OXF A;  3MO5 A;  4IJD A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...