2R3AA

Methyltransferase domain of human suppressor of variegation 3-9 homolog 2
Total Genus 81
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
287
structure length
270
Chain Sequence
AEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVTFGCSCTDCFFQKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGRVRTVCKCGAVTCRGYLN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural biology of human H3K9 methyltransferases
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Histone-lysine N-methyltransferase SUV39H2
total genus 81
structure length 270
sequence length 287
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2007-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 2r3aA00
4NVQA 5F5EA 4QENA 1XQHA 3SW9A 5EX3A 4MI0A 2O8JA 4J7FA 3KMAA 3VV0A 2G46A 4C1QA 3M54A 5T0KA 5TEGA 3S7FA 3RAYA 1N6CA 4J8OA 3RU0A 3DB5A 4QEOA 5CPRB 3BO5A 5EX0A 2QPWA 3MO5A 3OXFA 2F69A 4YNDA 4FMUA 3M56A 2W5YA 5HQ8A 3HNAA 4QEPA 3MO2A 3M53A 3PDNA 5AYFA 5EG2A 1MUFA 4WUYA 4YPUA 5TTFA 3RIBA 5F59A 3CBPA 1N6AA 3KMTA 3F9YA 1MVHA 5KJMA 2W5ZA 4IJDA 5ARFA 1O9SA 4YNMA 4BUPA 5CCMA 3OPEA 3IHXA 3QWVA 3F9ZA 3F9XA 2JV0A 3S8PA 1N3JA 1PEGA 5F6LA 5JHNA 4JLGA 3M59A 4YNPA 5CCLA 3S7JA 4AU7A 3SWCA 3CBMA 3TG4A 3KMJA 3K5KA 3MO0A 1MT6A 4YPAA 4Z4PA 1ZKKA 3VUZA 5KJLA 5JINA 3TG5A 3F9WA 1ML9A 4LDGA 4MI5A 5HI7A 5LSZA 3FPDA 3OOIA 4O6FA 3RJWA 3MEKA 3M57A 3M58A 5F6KC 3M5AA 4I51A 4O30A 3OS5A 4J7IA 4J83A 5LSXA 4H12A 3CBOA 2IGQA 3M55A 5TH7A 4IJ8A 3RQ4A 3DALA 4JDSA 4NJ5A 3N71A 3QWPA 5T0MA 2BQZA 4YPEA 2RFIA 5ARGA 3OXLA 1H3IA 4RZ0A 3EP0A 3S7BA 5KJNA 2R3AA 5T5GA 5KJKA 3QWWA 5JJ0A 4E47A 5JIYA 1MVXA 3S7DA 3OXGA
chains in the Genus database with same CATH superfamily
4NVQA 5F5EA 4QENA 1XQHA 3SW9A 5EX3A 4MI0A 2O8JA 4J7FA 3KMAA 3VV0A 2G46A 4C1QA 3M54A 5T0KA 5TEGA 3S7FA 3RAYA 1N6CA 4J8OA 3RU0A 3DB5A 4QEOA 5CPRB 3BO5A 5EX0A 2QPWA 3MO5A 3OXFA 2F69A 4YNDA 4FMUA 3M56A 2W5YA 5HQ8A 3HNAA 4QEPA 3MO2A 3M53A 3PDNA 5AYFA 5EG2A 1MUFA 4WUYA 4YPUA 5TTFA 3RIBA 5F59A 3CBPA 1N6AA 3KMTA 3F9YA 1MVHA 5KJMA 2W5ZA 4IJDA 5ARFA 1O9SA 4YNMA 4BUPA 5CCMA 3OPEA 3IHXA 3QWVA 3F9ZA 3F9XA 2JV0A 3S8PA 1N3JA 1PEGA 5F6LA 5JHNA 4JLGA 3M59A 4YNPA 5CCLA 3S7JA 4AU7A 3SWCA 3CBMA 3TG4A 3KMJA 3K5KA 3MO0A 1MT6A 4YPAA 4Z4PA 1ZKKA 3VUZA 5KJLA 5JINA 3TG5A 3F9WA 1ML9A 4LDGA 4MI5A 5HI7A 5LSZA 3FPDA 3OOIA 4O6FA 3RJWA 3MEKA 3M57A 3M58A 5F6KC 3M5AA 4I51A 4O30A 3OS5A 4J7IA 4J83A 5LSXA 4H12A 3CBOA 2IGQA 3M55A 5TH7A 4IJ8A 3RQ4A 3DALA 4JDSA 4NJ5A 3N71A 3QWPA 5T0MA 2BQZA 4YPEA 2RFIA 5ARGA 3OXLA 1H3IA 4RZ0A 3EP0A 3S7BA 5KJNA 2R3AA 5T5GA 5KJKA 3QWWA 5JJ0A 4E47A 5JIYA 1MVXA 3S7DA 3OXGA
chains in the Genus database with same CATH topology
4NVQA 5F5EA 4QENA 1XQHA 3SW9A 5EX3A 4MI0A 2O8JA 4J7FA 3KMAA 3VV0A 2G46A 4C1QA 3M54A 5T0KA 5TEGA 3S7FA 3RAYA 1N6CA 4J8OA 3RU0A 3DB5A 4QEOA 5CPRB 3BO5A 5EX0A 2QPWA 3MO5A 3OXFA 2F69A 4YNDA 4FMUA 3M56A 2W5YA 5HQ8A 3HNAA 4QEPA 3MO2A 3M53A 3PDNA 5AYFA 5EG2A 1MUFA 4WUYA 4YPUA 5TTFA 3RIBA 5F59A 3CBPA 1N6AA 3KMTA 3F9YA 1MVHA 5KJMA 2W5ZA 4IJDA 5ARFA 1O9SA 4YNMA 4BUPA 5CCMA 3OPEA 3IHXA 3QWVA 3F9ZA 3F9XA 2JV0A 3S8PA 1N3JA 1PEGA 5F6LA 5JHNA 4JLGA 3M59A 4YNPA 5CCLA 3S7JA 4AU7A 3SWCA 3CBMA 3TG4A 3KMJA 3K5KA 3MO0A 1MT6A 4YPAA 4Z4PA 1ZKKA 3VUZA 5KJLA 5JINA 3TG5A 3F9WA 1ML9A 4LDGA 4MI5A 5HI7A 5LSZA 3FPDA 3OOIA 4O6FA 3RJWA 3MEKA 3M57A 3M58A 5F6KC 3M5AA 4I51A 4O30A 3OS5A 4J7IA 4J83A 5LSXA 4H12A 3CBOA 2IGQA 3M55A 5TH7A 4IJ8A 3RQ4A 3DALA 4JDSA 4NJ5A 3N71A 3QWPA 5T0MA 2BQZA 4YPEA 2RFIA 5ARGA 3OXLA 1H3IA 4RZ0A 3EP0A 3S7BA 5KJNA 2R3AA 5T5GA 5KJKA 3QWWA 5JJ0A 4E47A 5JIYA 1MVXA 3S7DA 3OXGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NVQ A;  5F5E A;  4QEN A;  1XQH A;  3SW9 A;  5EX3 A;  4MI0 A;  2O8J A;  4J7F A;  3KMA A;  3VV0 A;  2G46 A;  4C1Q A;  3M54 A;  5T0K A;  5TEG A;  3S7F A;  3RAY A;  1N6C A;  4J8O A;  3RU0 A;  3DB5 A;  4QEO A;  5CPR B;  3BO5 A;  5EX0 A;  2QPW A;  3MO5 A;  3OXF A;  2F69 A;  4YND A;  4FMU A;  3M56 A;  2W5Y A;  5HQ8 A;  3HNA A;  4QEP A;  3MO2 A;  3M53 A;  3PDN A;  5AYF A;  5EG2 A;  1MUF A;  4WUY A;  4YPU A;  5TTF A;  3RIB A;  5F59 A;  3CBP A;  1N6A A;  3KMT A;  3F9Y A;  1MVH A;  5KJM A;  2W5Z A;  4IJD A;  5ARF A;  1O9S A;  4YNM A;  4BUP A;  5CCM A;  3OPE A;  3IHX A;  3QWV A;  3F9Z A;  3F9X A;  2JV0 A;  3S8P A;  1N3J A;  1PEG A;  5F6L A;  5JHN A;  4JLG A;  3M59 A;  4YNP A;  5CCL A;  3S7J A;  4AU7 A;  3SWC A;  3CBM A;  3TG4 A;  3KMJ A;  3K5K A;  3MO0 A;  1MT6 A;  4YPA A;  4Z4P A;  1ZKK A;  3VUZ A;  5KJL A;  5JIN A;  3TG5 A;  3F9W A;  1ML9 A;  4LDG A;  4MI5 A;  5HI7 A;  5LSZ A;  3FPD A;  3OOI A;  4O6F A;  3RJW A;  3MEK A;  3M57 A;  3M58 A;  5F6K C;  3M5A A;  4I51 A;  4O30 A;  3OS5 A;  4J7I A;  4J83 A;  5LSX A;  4H12 A;  3CBO A;  2IGQ A;  3M55 A;  5TH7 A;  4IJ8 A;  3RQ4 A;  3DAL A;  4JDS A;  4NJ5 A;  3N71 A;  3QWP A;  5T0M A;  2BQZ A;  4YPE A;  2RFI A;  5ARG A;  3OXL A;  1H3I A;  4RZ0 A;  3EP0 A;  3S7B A;  5KJN A;  2R3A A;  5T5G A;  5KJK A;  3QWW A;  5JJ0 A;  4E47 A;  5JIY A;  1MVX A;  3S7D A;  3OXG A; 
#chains in the Genus database with same CATH topology
 4NVQ A;  5F5E A;  4QEN A;  1XQH A;  3SW9 A;  5EX3 A;  4MI0 A;  2O8J A;  4J7F A;  3KMA A;  3VV0 A;  2G46 A;  4C1Q A;  3M54 A;  5T0K A;  5TEG A;  3S7F A;  3RAY A;  1N6C A;  4J8O A;  3RU0 A;  3DB5 A;  4QEO A;  5CPR B;  3BO5 A;  5EX0 A;  2QPW A;  3MO5 A;  3OXF A;  2F69 A;  4YND A;  4FMU A;  3M56 A;  2W5Y A;  5HQ8 A;  3HNA A;  4QEP A;  3MO2 A;  3M53 A;  3PDN A;  5AYF A;  5EG2 A;  1MUF A;  4WUY A;  4YPU A;  5TTF A;  3RIB A;  5F59 A;  3CBP A;  1N6A A;  3KMT A;  3F9Y A;  1MVH A;  5KJM A;  2W5Z A;  4IJD A;  5ARF A;  1O9S A;  4YNM A;  4BUP A;  5CCM A;  3OPE A;  3IHX A;  3QWV A;  3F9Z A;  3F9X A;  2JV0 A;  3S8P A;  1N3J A;  1PEG A;  5F6L A;  5JHN A;  4JLG A;  3M59 A;  4YNP A;  5CCL A;  3S7J A;  4AU7 A;  3SWC A;  3CBM A;  3TG4 A;  3KMJ A;  3K5K A;  3MO0 A;  1MT6 A;  4YPA A;  4Z4P A;  1ZKK A;  3VUZ A;  5KJL A;  5JIN A;  3TG5 A;  3F9W A;  1ML9 A;  4LDG A;  4MI5 A;  5HI7 A;  5LSZ A;  3FPD A;  3OOI A;  4O6F A;  3RJW A;  3MEK A;  3M57 A;  3M58 A;  5F6K C;  3M5A A;  4I51 A;  4O30 A;  3OS5 A;  4J7I A;  4J83 A;  5LSX A;  4H12 A;  3CBO A;  2IGQ A;  3M55 A;  5TH7 A;  4IJ8 A;  3RQ4 A;  3DAL A;  4JDS A;  4NJ5 A;  3N71 A;  3QWP A;  5T0M A;  2BQZ A;  4YPE A;  2RFI A;  5ARG A;  3OXL A;  1H3I A;  4RZ0 A;  3EP0 A;  3S7B A;  5KJN A;  2R3A A;  5T5G A;  5KJK A;  3QWW A;  5JJ0 A;  4E47 A;  5JIY A;  1MVX A;  3S7D A;  3OXG A; 
#chains in the Genus database with same CATH homology
 4NVQ A;  5F5E A;  4QEN A;  1XQH A;  3SW9 A;  5EX3 A;  4MI0 A;  2O8J A;  4J7F A;  3KMA A;  3VV0 A;  2G46 A;  4C1Q A;  3M54 A;  5T0K A;  5TEG A;  3S7F A;  3RAY A;  1N6C A;  4J8O A;  3RU0 A;  3DB5 A;  4QEO A;  5CPR B;  3BO5 A;  5EX0 A;  2QPW A;  3MO5 A;  3OXF A;  2F69 A;  4YND A;  4FMU A;  3M56 A;  2W5Y A;  5HQ8 A;  3HNA A;  4QEP A;  3MO2 A;  3M53 A;  3PDN A;  5AYF A;  5EG2 A;  1MUF A;  4WUY A;  4YPU A;  5TTF A;  3RIB A;  5F59 A;  3CBP A;  1N6A A;  3KMT A;  3F9Y A;  1MVH A;  5KJM A;  2W5Z A;  4IJD A;  5ARF A;  1O9S A;  4YNM A;  4BUP A;  5CCM A;  3OPE A;  3IHX A;  3QWV A;  3F9Z A;  3F9X A;  2JV0 A;  3S8P A;  1N3J A;  1PEG A;  5F6L A;  5JHN A;  4JLG A;  3M59 A;  4YNP A;  5CCL A;  3S7J A;  4AU7 A;  3SWC A;  3CBM A;  3TG4 A;  3KMJ A;  3K5K A;  3MO0 A;  1MT6 A;  4YPA A;  4Z4P A;  1ZKK A;  3VUZ A;  5KJL A;  5JIN A;  3TG5 A;  3F9W A;  1ML9 A;  4LDG A;  4MI5 A;  5HI7 A;  5LSZ A;  3FPD A;  3OOI A;  4O6F A;  3RJW A;  3MEK A;  3M57 A;  3M58 A;  5F6K C;  3M5A A;  4I51 A;  4O30 A;  3OS5 A;  4J7I A;  4J83 A;  5LSX A;  4H12 A;  3CBO A;  2IGQ A;  3M55 A;  5TH7 A;  4IJ8 A;  3RQ4 A;  3DAL A;  4JDS A;  4NJ5 A;  3N71 A;  3QWP A;  5T0M A;  2BQZ A;  4YPE A;  2RFI A;  5ARG A;  3OXL A;  1H3I A;  4RZ0 A;  3EP0 A;  3S7B A;  5KJN A;  2R3A A;  5T5G A;  5KJK A;  3QWW A;  5JJ0 A;  4E47 A;  5JIY A;  1MVX A;  3S7D A;  3OXG A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...